Dustin Borg, ME Patrick Henley, BME Ali Husain, BME Nick Stroeher, BME Advisor: Dr. Paul King

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Dustin Borg, ME Patrick Henley, BME Ali Husain, BME Nick Stroeher, BME Advisor: Dr. Paul King. Our Dutch Team Members. Willem-Jan van Harskamp, Applied Physics Vivian Roode, BME Gijs Snieders, BME M. van Vlimmeren, BME Advisor: Dr. Eva Adamowicz. Relevance. Dental applications: - PowerPoint PPT Presentation

Transcript of Dustin Borg, ME Patrick Henley, BME Ali Husain, BME Nick Stroeher, BME Advisor: Dr. Paul King

  • Dustin Borg, MEPatrick Henley, BMEAli Husain, BMENick Stroeher, BME

    Advisor: Dr. Paul King

  • Our Dutch Team MembersWillem-Jan van Harskamp, Applied PhysicsVivian Roode, BMEGijs Snieders, BMEM. van Vlimmeren, BME

    Advisor: Dr. Eva Adamowicz

  • RelevanceDental applications:Clean cavitiesLess painfulTreat irregular surfaces

  • Skin treatmenthealing of various lesions and ulcers of skin, intestines and larynx

  • Current Level of Development of Plasma Needle TechnologyEvaluation of the electrical characteristics of the plasma needleSensing the gap width by monitoring the discharge power consumptionControl of the gap width with robotic actuation

  • What We Will ContributeEindhoven Students:Correct gap width by implementing electro-mechanical actuators and control algorithms

    Vanderbilt Students:Design a plasma needle catheter that will be better suited for medical use than the existing prototypePossibly testing on cell cultures

  • Our Progress So FarResearchLiterature from Eindhoven

    CoordinationOverseas communication issuesNetMeeting

  • What is Plasma?Plasma is a state of matter with enough free charged particles so that its dynamics are heavily influenced by electromagnetic forces. gaseous fluid-like mixture of ions, free electrons,radicals and excited atoms and moleculesThe Plasma Needle uses Low-Temperature Plasma (LTP) small fraction of neutral particles in gas are ionized electrons are high energy; ions are ambient temp. retains neutral charge

    http://solar.physics.montana.edu/martens/plasma/

  • Composition of the Needle

    ____The AC source produces Radio Frequent (RF) discharges on the order of 1-100 MHz____This design uses Capacitively Coupled Plasma to create E field from voltage difference____In the middle is a metal wire with a sharp point electrode for the E field____The coaxial metal tube is grounded Helium gas is moved into space between____Wire is insulated so that plasma is generated only at tip; it appears like a ball 1 mm in diameter____The Development of a Smart-Scanning Probe for the Plasma Needle, Ewout van der Laan

  • The Plasma NeedleThe Development of a Smart-Scanning Probe for the Plasma Needle, Ewout van der Laan

  • Current Known EffectsMain effect is the dissolution of tissue

    Most likely Plasma Needle damages CAM proteins and causes breakup of tissue without accidentally killing cells

    Destruction of CAM proliferation of free radicals (O, OH)The Development of a Smart-Scanning Probe for the Plasma Needle, Ewout van der Laan

  • Gas Plasma CatheterBasic DefinitionPlastic tube confining thin wire containing plasma electrode for insertion into the body (bloodstream, lungs, etc.). General Design GoalsBiocompatibleThinFlexibleCapable of separating gas from tissue and fluidsPorous MembraneMaintain plasma operation under closedconditionsPermit sufficient active plasma particles to escape through membrane

  • Immediate Goals(through end of semester)Construction of plasma needle prototypeAcquire current schematics Arrange for financingIdentify and select manufacturing contactFocused research efforts CatheterMaterialsSpecificationsSelectively Porous MembranesSolidify CoordinationMaintain contact with our counterpartsExpand and improve lines of communication

  • TimelineDecember

    January

    February

    March

    April

    Catheter ResearchConstruction of Functioning Plasma Needle SetupMaterial Selection and Design of CatheterCatheter ConstructionPhysical Testing of Plasma Needle Catheter CombinationTherapeutic Testing on Tissue Cultures