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DRUG STUDY

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ASSESSMENT CLASSIFICATION ACTION DOSAGE

NURSING

CONSIDERATION EVALUATION

Generic Name:Acetylcysteine

Brand Name:

Mucomyst

Pharmacologic:Amino acid (L cysteine)derivative

Therapeutic:

Mucolytic, antidote for

acetaminophen overdose

Increase respiratory

tract fluid to help

liquefy tenacioussecretions. Restoresglutathione in liver

to treat

acetaminophentoxicity

600mg 1 tabin 200 ml ofwater, OD

Assess patients

respiratory secretionsbefore and often during

therapy.

Be alert for adverse

reactions and drug

interactions.

drug is incompatible

with tetracyclines,

erythromycinlactobionate,

amphotericin B and

ampicillin sodium.

Have suction equipment

available in case patientcant effectively clear air

passages.

Alert prescriber isrespiratory secretions

thickens or become

purulent or if bronchospasmoccur.

Activated charcoal may

limit acetylcyteineseffectiveness. Avoid use

together.

Patient has clear

lung sounds,decrease respiratory

secretions, reduced

frequency and

severity of cough.

patient and family

state understanding

of drug therapy.

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ASSESSMENT CLASSIFICATION ACTION DOSAGE

NURSING

CONSIDERATION EVALUATION

Generic Name:

Ampicillin sodiumand sulbactam sodium

(Ampi-sulbactam)

Brand Name:Unasyn

Pharmacologic:

Aminopenicillin and beta

lactamase inhibitor.

Therapeutic:

Antibiotic

Ampicillin inhibitscell wall synthesis

duringmicroorganism

multiplication.

Sulbactaminactivates bacterial

beta-lactamase theenzymes that

inactivates

ampicillin andprovides bacterial

resistance to it.

105 g TIV as

loading dose 1hour prior

then 750 mg

TIV q6h, (-)ANST

Obtain history of patientsinfection before therapy and

observe throughout therapyto determine improvement.

Ask patient about previous

allergic reactions topenicillin.

Obtain specimen forculture and sensitivity.

Be alert for adverse

reaction and drug interaction May increase BUN,

creatinine, AST, ALT,Alkaline phosphatase,

bilirubin, LDH, CK andGGT level.

May decrease Hgb and Hct

level.Probenecid increases

ampicillin level.Tell patient to call

prescriber if rash, fever or

chills develop.If adverse GI reaction

occurs, monitor patientshydration.

Monitor liver function test

Patient is free frominfection.

Patient and familystate understanding of

drug therapy.

Patient decreased themultiplication of

bacteria or lessen theproduction of bacteria

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result during therapy,especially in patients with

impaired liver function.

ASSESSMENT CLASSIFICATION ACTION DOSAGE

NURSING

CONSIDERATION EVALUATION

Generic Name:Metoprolol

Pharmacologic:

Selective beta1 bloker

Known to depress

rennin secretion.Reduces Bp,

decreases

50 mg, I tabBID

Assess patients condition

before starting therapy andregularly thereafter to

monitor drug effectiveness.

Patient responds well

to therapy.Patient does not

experience injury from

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Brand Name:Neobloc

Thereapeutic: anti-

hypertensive, adjunct

therapy of acute MI.

myocardialcontractility, HR

and cardiac output

Monitor blood pressureoften.

Always monitor apicalpulse rate before giving.

Below 60 beats/ min. do notgive drug and call theprescriber.

If P.O give drug withmeals because food may

increase absorption.

Be alert for adversereaction and drug

interactions. Instruct patientto report these reactions.

Warn patient to avoidperforming hazardous

activities until drugs CNS

effects are known.

adverse CNs reactions.Patient and family

state understanding ofdrug therapy.

ASSESSMENT CLASSIFICATION ACTION DOSAGE

NURSING

CONSIDERATION EVALUATION

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Generic Name:Atorvastatin sodium

Brand Name:lipitor

Pharmacologic:

HMG-COA reductase

inhibitor

Therapeutic:

Anti-lipemic

Selectively

inhibits HMG-CoA reductase

which convertsHMG-CoA tomevalonate- a

precursor ofsterols.

Lowers

cholesterol andlipoprotein levels.

80 mg, 1 tab.OD/Hs

Monitor patients lipid and

liver function levels atbaseline and periodically

thereafter. Drug can be given as asingle dose with or without

food. Teach patient about proper

diet, weight control and

explain their role incontrolling lipid levels.

Tell patient to informprescriber of adverse

reactions such as musclepain, tenderness, or

weakness esp. if patient

accompanied by fever ormalaise.

May increase digoxinlevel. Monitor level.

Warfarin may increaseanti-coagulant effect.

Antacids may decreasebio-availability.

Patients cholesterol

level is within normallevels.

http://general-medicine.jwatch.org/cgi/content/full/2011/505/3

http://general-medicine.jwatch.org/cgi/content/full/2011/505/3http://general-medicine.jwatch.org/cgi/content/full/2011/505/3

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http://general-medicine.jwatch.org/cgi/content/full/2011/621/2

http://general-medicine.jwatch.org/cgi/content/full/2011/621/2http://general-medicine.jwatch.org/cgi/content/full/2011/621/2