Drug Literature on Osteoporosis
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Transcript of Drug Literature on Osteoporosis
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8/12/2019 Drug Literature on Osteoporosis
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Strengthens bone health & leads to a dynamic life!
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8/12/2019 Drug Literature on Osteoporosis
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Forms Healthy
Cartilage and Collagen
Increases Bone Mineral
Density
Reduces the Risk of
Bone Fracture
(Titan Biosciences, 2010)
(National Institute of Health, 2011)
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8/12/2019 Drug Literature on Osteoporosis
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Abbreviated Prescribing InformationComposition: each tablet contains calcium carbonate USP equivalent to 500 mg elemental Calcium. Therapeutic
indication: 1. raised calcium requirement, e.g. during pregnancy and lactation and in children and adolescents at times of
rapid growth. 2.inadequate intake of calcium in the diet due to malnutrition. 3.prevention and treatment of osteoporosis.
4. disorders of osteogenesis. Dosage and administration: for adult one tablet (500 mg elemental calcium) daily or as
directed by the physician. For children 250 mg elemental calcium daily or as directed by the physician. For adolescents250-500 mg elemental calcium daily or as directed by the physician. Contraindication: hypersensitivity to the calcium
carbonate or any inactive ingredient of the medication. Hypercalcaemia (e.g. in hyperparathyroidism, demineralizing
tumours such as plasmacytomas and bone metastases). Severe hypercalciuria. Severe renal insufficiency. Pregnancy and
Lactation: During pregnancy and lactation treatment should always be under the direction of a physician. During
pregnancy and lactation, requirements for calcium and vitamin D are increased but in deciding on the required
supplementation allowances should be made for availability of these agents from other sources. Side effects: flatulence,
diarrhea or constipation in rare cases. Drug interaction: oral calcium can reduce the eternal absorption of tetracycline and
oral fluoride preparations. An interval of at least 3 hours should therefore be allowed between ingestion of these
medications. Vitamin D increases enteral absorption of calcium. The intestinal uptake of calcium from the tablet may be
reduced by concomitant ingestion of certain foods (e.g. spinach, rhubarb, bran, and other cereal products, milk and milk
products). At high doses and in combination with vitamin D, calcium may decrease the response of verapamil andpossibly to other calcium antagonists. In digitalized patients, high doses of calcium may increase the risk of cardiac
arrhythmias (ACI Limited, 2014).
Raises Calcium Requirement
Provides a Complete Treatment in Disorders
of Osteogenesis & Tooth Formation
Calviteo
1. ACI Limited (2014) Acical 500: Calcium carbonate tablet Available from: http://www.aci-bd.com/Brand/Acical.pdf [Accessed 31st March 2014]
2. International Osteoporosis Foundation (2014) Treating Osteoporosis Available from: http://www.iofbonehealth.org/treating-osteoporosis
[Accessed 31st March 2014]
3. National Institute of Health (2011) Dont Let Osteoporosis Slow You Down MedlinePlusVolume 5 Number 4 Page 15
4. Sina Pharm (2011) OsteoCalVit, OsteoCalVitFort Available from: http://www.sinapharm.com/?page_id=36 *Accessed 31st March 2014+
5. Titan Biosciences (2010) CALLICOR FOR BONES Available from: http://titanbio.com/about_callicor.html *Accessed 31st March 2014+
Calviteo