Drug Literature on Osteoporosis

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    Strengthens bone health & leads to a dynamic life!

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    Forms Healthy

    Cartilage and Collagen

    Increases Bone Mineral

    Density

    Reduces the Risk of

    Bone Fracture

    (Titan Biosciences, 2010)

    (National Institute of Health, 2011)

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    Abbreviated Prescribing InformationComposition: each tablet contains calcium carbonate USP equivalent to 500 mg elemental Calcium. Therapeutic

    indication: 1. raised calcium requirement, e.g. during pregnancy and lactation and in children and adolescents at times of

    rapid growth. 2.inadequate intake of calcium in the diet due to malnutrition. 3.prevention and treatment of osteoporosis.

    4. disorders of osteogenesis. Dosage and administration: for adult one tablet (500 mg elemental calcium) daily or as

    directed by the physician. For children 250 mg elemental calcium daily or as directed by the physician. For adolescents250-500 mg elemental calcium daily or as directed by the physician. Contraindication: hypersensitivity to the calcium

    carbonate or any inactive ingredient of the medication. Hypercalcaemia (e.g. in hyperparathyroidism, demineralizing

    tumours such as plasmacytomas and bone metastases). Severe hypercalciuria. Severe renal insufficiency. Pregnancy and

    Lactation: During pregnancy and lactation treatment should always be under the direction of a physician. During

    pregnancy and lactation, requirements for calcium and vitamin D are increased but in deciding on the required

    supplementation allowances should be made for availability of these agents from other sources. Side effects: flatulence,

    diarrhea or constipation in rare cases. Drug interaction: oral calcium can reduce the eternal absorption of tetracycline and

    oral fluoride preparations. An interval of at least 3 hours should therefore be allowed between ingestion of these

    medications. Vitamin D increases enteral absorption of calcium. The intestinal uptake of calcium from the tablet may be

    reduced by concomitant ingestion of certain foods (e.g. spinach, rhubarb, bran, and other cereal products, milk and milk

    products). At high doses and in combination with vitamin D, calcium may decrease the response of verapamil andpossibly to other calcium antagonists. In digitalized patients, high doses of calcium may increase the risk of cardiac

    arrhythmias (ACI Limited, 2014).

    Raises Calcium Requirement

    Provides a Complete Treatment in Disorders

    of Osteogenesis & Tooth Formation

    Calviteo

    1. ACI Limited (2014) Acical 500: Calcium carbonate tablet Available from: http://www.aci-bd.com/Brand/Acical.pdf [Accessed 31st March 2014]

    2. International Osteoporosis Foundation (2014) Treating Osteoporosis Available from: http://www.iofbonehealth.org/treating-osteoporosis

    [Accessed 31st March 2014]

    3. National Institute of Health (2011) Dont Let Osteoporosis Slow You Down MedlinePlusVolume 5 Number 4 Page 15

    4. Sina Pharm (2011) OsteoCalVit, OsteoCalVitFort Available from: http://www.sinapharm.com/?page_id=36 *Accessed 31st March 2014+

    5. Titan Biosciences (2010) CALLICOR FOR BONES Available from: http://titanbio.com/about_callicor.html *Accessed 31st March 2014+

    Calviteo