Table 1. Top 100 Drugs by Sales Rank Drug (brand name) Sales, 2013 1 Abilify $6,460,215,3942 Nexium $6,135,667,6143 Humira $5,549,996,8554 Crestor $5,310,818,8895 Cymbalta $5,219,860,4186 Advair Diskus $5,121,312,6687 Enbrel $4,681,201,6458 Remicade $4,098,233,2429 Copaxone $3,697,182,23810 Neulasta $3,580,364,75811 Rituxan $3,288,614,04512 Lantus Solostar $3,005,681,66313 Spiriva Handihaler $2,998,207,54214 Atripla $2,856,818,55715 Januvia $2,843,496,90716 Avastin $2,688,414,93817 Lantus $2,556,825,61918 Oxycontin $2,534,909,67519 Lyrica $2,415,254,83520 Epogen $2,280,696,83421 Celebrex $2,237,658,76422 Truvada $2,235,712,14523 Diovan $2,169,819,48224 Herceptin $1,938,804,85725 Gleevec $1,896,982,61426 Lucentis $1,859,463,48427 Namenda $1,856,822,75028 Vyvanse $1,743,115,52129 Zetia $1,710,526,47630 Symbicort $1,563,242,16131 Levemir $1,547,629,74532 Suboxone $1,450,554,13033 Novolog Flexpen $1,377,221,61434 Novolog $1,349,403,12235 Avonex $1,240,754,13636 Seroquel Xr $1,226,532,01937 Viagra $1,196,812,38538 Alimta $1,192,134,81339 Humalog $1,184,189,48740 Nasonex $1,137,402,45541 Victoza 3-Pak $1,104,811,63742 Cialis $1,086,355,58343 Gilenya $1,059,346,32344 Flovent Hfa $1,050,009,900

45 Procrit $1,030,419,95846 Isentress $1,014,678,05547 Xarelto $996,441,09148 Prezista $992,087,94049 Janumet $987,663,59850 Stelara $965,072,89251 Neupogen $958,807,37252 Orencia $957,680,50053 Renvela $955,330,19954 Reyataz $934,879,38855 Vesicare $933,311,25456 Dexilant $916,401,20457 Tecfidera $879,673,48358 Humalog Kwikpen $879,632,96259 Synthroid $858,725,70860 Vytorin $858,576,11261 Lunesta $851,791,22662 Pradaxa $836,573,80563 Benicar $832,276,97064 Evista $823,647,43365 Xolair $821,783,47166 Aranesp $809,245,70067 Prevnar 13 $806,129,34668 Sensipar $786,320,94269 Xgeva $785,725,43670 Invega Sustenna $779,834,17271 Zytiga $775,269,24972 Avonex Pen $768,655,14073 Synagis $767,786,42274 Betaseron $767,648,29075 Xeloda $754,133,78776 Ventolin Hfa $745,629,47077 Zyvox $726,184,20578 Afinitor $721,629,71979 Gardasil $710,208,85680 Zostavax $705,140,72981 Incivek $701,317,40882 Sandostatin Lar $697,961,26583 Aciphex $683,359,95184 Benicar Hct $681,353,71985 Bystolic $681,318,22786 Treanda $679,052,25087 Focalin Xr $660,161,20288 Erbitux $648,984,40589 Tamiflu $641,134,79990 Tarceva $640,597,157

91 Pristiq $632,619,54292 Complera $630,039,31293 Cubicin $628,034,43994 Velcade $621,800,82395 Strattera $616,604,04296 Viread $599,074,19797 Stribild $598,844,15398 Welchol $573,939,71099 Combivent Respimat$573,179,772100 Xifaxan $569,762,570

 

RankProduct Manufacturer Sales ($) RankProduct Manufacturer Sales ($)

1 Nexium AstraZeneca$5,989,000,000

11 SingulairMerck & Company

$3,300,000,000

2 Abilify Otsuka America$5,870,000,000

12 Rituxan Genentech $3,197,000,000

3 Crestor AstraZeneca$5,092,000,000

13 PlavixBristol-Myers Squibb/sanofi-aventis

$2,971,000,000

4Advair Diskus

GlaxoSmithKline

$4,889,000,000

14 AtriplaBristol-Myers Squibb Gilead

$2,899,000,000

5 Cymbalta Lilly$4,720,000,000

15Spiriva Handihaler

Boehringer Ingelheim

$2,833,000,000

6 Humira Abbvie$4,609,000,000

16 OxycontinPurdue Pharma

$2,808,000,000

7 Enbrel Amgen$4,337,000,000

17 JanuviaMerck & Company

$2,670,000,000

8 RemicadeCentocor$3,876,000,000

18 Avastin Genentech $2,661,000,000

9 CopaxoneTeva CNS$3,581,000,000

19 Lantus sanofi-aventis $2,327,000,000

10 Neulasta Amgen$3,460,000,000

20 TruvadaGilead Sciences

$2,305,000,000

 

Rank

ProductManufacturer

Rank

ProductManufacturer

Rank

ProductManufacturer

21Lantus Solostar

sanofi-aventis 81 Lexapro Forest 141Risperdal Consta

Janssen

22 Epogen Amgen 82 Synagis Medimmune 142 Premarin Pfizer

23 Diovan Novartis Rx 83 BenicarDaiichi Sankyo

143 Zytiga Centocor

24 Lyrica Pfizer 84 Lunesta Sunovion 144 WelcholDaiichi Sankyo

25 Lipitor Pfizer 85 Evista Lilly 145Metoprolol Succinate

Par Pharm

26 Celebrex Pfizer 86 Prevnar 13 Pfizer 146 OnglyzaBristol-Myers Squibb

27 Herceptin Genentech 87Enoxaparin Sodium

Sandoz 147 Xifaxan Salix

28 Gleevec Novartis Rx 88 Synthroid Abbvie 148 Byetta Amylin

29 Namenda Forest 89 Renvela Genzyme 149 AggrenoxBoehringer Ingelheim

30 Actos Takeda USA 90Atorvastatin Calcium

Actavis 150 Opana Er Endo Labs

31 Avonex Biogen 91 Xeloda Roche 151 Aloxi Eisai

32 Lucentis Genentech 92 Zyvox Pfizer 152 Privigen CSL Behring

33 Vyvanse Shire Us Inc 93Ventolin HFA

GlaxoSmithKline

153 Lumigan Allergan

34 SuboxoneReckitt Benckiser

94 Velcade Millennium 154 Intuniv Shire US

35 Seroquel AstraZeneca 95 Xolair Genentech 155 Travatan ZNovartis Vision

36 ZetiaMerck/Schering-Plough

96 Sensipar Amgen 156 PulmozymeGenentech

37Methylphenidate ER

Actavis 97 ErbituxImclone Systems

157Pneumovax 23

Merck & Company

38 Androgel Abbvie 98Humalog Kwikpen

Lilly 158 Zyprexa Lilly

39 Incivek Vertex 99 Stelara Centocor 159HYCD/APAP

Actavis

40 Diovan HCT Novartis Rx 100 Xgeva Amgen 160 AngiomaxThe Medicines Co

41 Lidoderm Endo Labs 101Benicar HCT

Daiichi Sankyo

161 Lialda Shire US

42Atorvastatin Calcium

Ranbaxy 102Sandostatin LAR

Novartis Rx 162 Cimzia UCB Pharma

43 Symbicort AstraZeneca 103 MirenaBayer Healthcare

163 Geodon Pfizer

44 Rebif EMD Serono 104 ZostavaxMerck & Company

164 ActonelWarner-Chilcott

45 Novolog Novo Nordisk 105Focalin XR

Novartis Rx 165 Prograf Astellas

46 Seroquel XR AstraZeneca 106 Tarceva Genentech 166 Fentanyl Mylan

47 Tricor Abbvie 107 Cubicin Cubist 167Ortho-Tri-cyclen Lo 28

Ortho

48 Alimta Lilly 108 Detrol LA Pfizer 168Novolog Flxpen Mix

Novo Nordisk

49 Eloxatin sanofi-aventis 109 Zometa Novartis Rx 169 RanexaGilead Sciences

50 Levemir Novo Nordisk 110 TreandaTeva Oncology

170 QvarTeva Respiratory

51 CombiventBoehringer Ingelheim

111 Colcrys Takeda USA 171 Afinitor Novartis Rx

52 Viagra Pfizer 112 Solodyn Medicis 172 Invega Janssen

53 Proair HFATeva Respiratory

113Escitalopram Oxalate

Teva 173 Tysabri Elan

54 Procrit Ortho Biotech 114 GardasilMerck & Company

174 Temodar Schering

55 Niaspan Abbvie 115 Pristiq Pfizer 175 Nuvigil Teva CNS

56 Nasonex Schering 116Pegasys Convenience Pack

Roche 176 SprycelBristol-Myers Squibb

57Novolog Flexpen

Novo Nordisk 117Invega Sustenna

Janssen Pharm177 Tasigna Novartis Rx

58 LovazaGlaxoSmithKline

118 Strattera Lilly 178 Adacel sanofi-aventis

59 Humalog Lilly 119 Trilipix Abbvie 179 Valcyte Roche

60 Flovent HFAGlaxoSmithKline

120 Revlimid Celgene 180 Exforge Novartis Rx

61 Neupogen Amgen 121 AsacolWarner-Chilcott

181Nutropin AQ

Genentech

62 ReyatazBristol-Myers Squibb HIV

122 Bystolic Forest 182 Zosyn Pfizer

63 VytorinMerck & Company

123 VireadGilead Sciences

183Amphetamine Salts

Teva

64 IsentressMerck & Company

124Enoxaparin Sodium

Winthrop 184 Effient Lilly

65 Budesonide Teva 125Loestrin 24 Fe

Warner-Chilcott

185 Claravis Teva

66 JanumetMerck & Company

126 YervoyBristol-Myers Squibb

186Advair HFA

GlaxoSmithKline

67 Aranesp Amgen 127 AvodartGlaxoSmithKline

187 Chantix Pfizer

68 Cialis Lilly 128 Lexiscan Astellas 188 Reclast Novartis Rx

69 Aciphex Eisai 129 Lovenox sanofi-aventis 189 Vidaza Celgene

70 Adderall XR Shire US 130 EpzicomViiv Healthcare

190 Abraxane Celgene

71 Restasis Allergan 131 Exelon Novartis Rx 191Gammagard Liquid

Baxter Hyland

72 PradaxaBoehringer Ingelheim

132Amphetamin Salt ER

Global 192 Tamiflu Roche

73 Gilenya Novartis Rx 133Gamunex-C

Grifols USA 193 CompleraGilead Sciences

74 Prezista Ortho Biotech 134 Nuvaring Organon 194 MaxaltMerck & Company

75 BetaseronBayer Healthcare

135Amphetamin Salt Er

Teva 195 CiprodexNovartis Vision

76 OrenciaBristol-Myers Squibb

136Escitalopram Oxal

Mylan 196 Activase Genentech

77 VarivaxMerck & Company

137 Provigil Teva CNS 197 Vimpat Schwarz

78 Vesicare Astellas 138 Norvir Abbvie 198 Simponi Centocor

79 Victoza 3-PakNovo Nordisk 139Epipen 2-Pak

Mylan Specialty

199Synvisc-One

Genzyme Corp

80 Dexilant Takeda USA 140 Forteo Lilly 200 Sutent Pfizer