Drug List #1

Pharmacology Mod 400

Lasixfurosemide

• Diuretic• Loop diuretic (loop of Henel)• Inhibits reabsorption of sodium.• Increases water excretion• Most potent diuretic• Warnings

• Replace K• Take with food or milk

Lasix cont.• Photosensitivity• Watch for dehydration• Interacts with Digoxin, anticoagulants,

Nsaids, and aminoglycosides.

Microzidehydrochlorothiazide

• Diuretic• Action

• Inhibits reabsorption of NaCl• Increases water elimination• Inhibits reabsorption of K and CA

• Indication• Edema• HTN

HCTZ Cont. • Warnings

• Replace K• Take with food or milk• Photosensitivity• Watch for dehydration• Drugs are related to sulfa

HCTZ Cont.Also know as Hctz most commonly

referred to by DR’s

Aldactonespironolactone

• Diuretic• Aldosterone receptor blocker• Indications

• Edema• Htn

• Action• Inhibits reabsorption of sodium and

water by competitively inhibiting aldosterone.

Aldactone cont.• Causes less K loss

• Warnings• D/D• Take with food or milk• May reduce serum testosterone levels

resulting in gynecomastia and reduced sex drive

Aldactone cont.• Drug interactions

• Digoxin• Anticoagulants• Ace inhibitors

Maxzide/Dyazidetriamterne/

hydrochlorothiazide• See Hctz

K-Durpotassium chloride

• Indication• hypokalemia

• Warnings• replaces potassium

• Interactions• Take with food/milk• Take with plenty of water

EPOGEN/PROCRITepoetin alfa recombinant

• Indication• anemia associated with renal failure,

treatment induced anemia in HIV or cancer chemotherapy

• Action• mimics natural erythropoietin

stimulating RBC production

Epogen/Procrit cont.• Warning

• keep refrigerated.• For SC or IV use only.• Do not shake..

•  procrit - Google Videos

Neupogenfilgrastim

• Indication: • decrease infections in persons

receiving chemotherapy• Action:

• mimics natural G-CSF stimulating neutrophil production

Neupogen cont.• Warnings:

• refrigerate,• do not shake.• For SC or IV use.• May cause n/v, • bone pain.

Pyridiumphenazopyridine

• Indication: • relief of pain, discomfort caused by

UTI• Action:

• unknown.• Local analgesic effect.

Pyridium cont.• Warnings:

• may discolor urine,• take with food. • Drink 2-3l of fluid daily. • For short term use only

Ciprociprofloxacin

• Fluoroquinolone antibiotic• Indication:

• UTIs• Action:

• interferes with DNA gyrase in bacteria. Effective against gram-positive and gram-negative.

Cipro cont.• Warnings:

• do not take with milk or antacids, • photosensitivity,• D/D, • increase water intake,• may decrease effectiveness of BCPs. • Avoid use in children,• may damage cartilage and surrounding tissues

Macrodantin/Macrobid

nitrofurantoin• Indication:

• prevention and treatment of UTIs• Action:

• inhibits protein, DNA, RNA and cell wall synthesis

• Warnings: • take w/food or milk, may discolor

urine, avoid alcohol•  

Osmitrolmannitol

• Indications: • promote diuresis in acute renal

failure, intracranial edema, promote urinary excretion of toxins, GU irrigant

• Action:• increases urinary output by

increasing osmotic pressure of glomerular filtrate

Osmitrol

• Warnings:• protect from low temperatures, • this may cause crystallization. • These crystals may be dissolved with

heat and shaking—follow instructions. Exposure to pvc may cause white flocculent precipitate.

Calcium Chloridecalcium chloride

• Replacement therapy• Indications:

• to replace or augment bodies nutrients due to disease or treatments

• Electrolytes are essential for body’s function.

• Diuretics for example can detrimentally deplete supply affecting body function. May be used in TPN

• Care must be taken that patient does not develop a hyper state of these chemicals

•  

CA CONT.• Diuretics for example can

detrimentally deplete supply affecting body function. May be used in TPN

• Care must be taken that patient does not develop a hyper state of these chemicals

MagOxmagnesium oxide