Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of...

41
Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery

TAGS:

Transcript of Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of...

Page 1: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

Drug Coated Balloons for PAD

William B. Newton III, MDAssistant Professor of Surgery

Department of Vascular and Endovascular Surgery

Page 2: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

Contents

Introduction PAD Burden Anatomy of a Drug

Coated Balloon LUTONIX® 035 Device

Overview Product Offering

Procedure Steps

LUTONIX® 035 Treatment Algorithm

LUTONIX® 035 Pre-Clinical Evidence

LEVANT2ClinicalTrial LEVANT2ClinicalCase

Studies Resources

Page 3: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

Introduction

DCB available: LUTONIX® 035 Drug Coated Balloon is the first and

ONLY of its kind technology in the U.S. that can advance our treatment algorithm for SFA/Popliteal disease.

Others are in the process of obtaining FDA approval.

Page 4: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

Peripheral Artery Disease Impact

Page 5: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

Anatomy of DCB

Page 6: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Formulation

Page 7: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Development

Page 8: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Design

Page 9: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCD Carriers

Page 10: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Coating Integrity

Page 11: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Coating Integrity

Page 12: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Coating Uniformity

Page 13: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Coating Uniformity

Page 14: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Mechanism of Action

Page 15: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Preclinical Safety Data

Page 16: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Preclinical Safety Data

Page 17: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: LEVANT 2

Page 18: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: LEVANT 2

Page 19: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: LEVANT 2

Page 20: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: LEVANT 2

Page 21: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: LEVANT 2

Page 22: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: LEVANT 2

Page 23: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: LEVANT 2

Page 24: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: LEVANT 2

Page 25: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: LEVANT 2

Page 26: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB IFU

Page 27: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Offering

Page 28: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Treatment Considerations

Page 29: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Procedure

Page 30: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Procedure Steps

Page 31: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Procedure Steps

Page 32: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB Procedure Steps

Page 33: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: Antiplatelet Regimen

Page 34: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: Summary

Page 35: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: Case 1

Page 36: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: Case 2

Page 37: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: Case 3

Page 38: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: Case 4

Page 39: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: Case 5

Page 40: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: Case 6

Page 41: Drug Coated Balloons for PAD William B. Newton III, MD Assistant Professor of Surgery Department of Vascular and Endovascular Surgery.

DCB: Questions

?


Vascular and Endovascular Surgery Fellowship Programassets.cooperhealth.org/pdf/VascularSurgeryFellowship_Final_2.pdf · 2015 / 2016 Vascular and Endovascular Surgery Fellowship Program

Vascular and Endovascular Surgery Fellowship Programassets.cooperhealth.org/pdf/VascularSurgeryFellowship_Final_2.pdf · 2015 / 2016 Vascular and Endovascular Surgery Fellowship Program

Vascular and Endovascular Surgery - NYP.org · 2019-05-22 · and Endovascular Surgery. We perform both minimally invasive endovascular procedures and traditional open surgery based

Vascular and Endovascular Surgery - NYP.org · 2019-05-22 · and Endovascular Surgery. We perform both minimally invasive endovascular procedures and traditional open surgery based

Frank R. Arko, III, MD Director, Endovascular Surgery … · Frank R. Arko, III, MD Director, Endovascular Surgery Co-Director Aortic Institute Sanger Heart and Vascular Institute

Frank R. Arko, III, MD Director, Endovascular Surgery … · Frank R. Arko, III, MD Director, Endovascular Surgery Co-Director Aortic Institute Sanger Heart and Vascular Institute

CIRUGÍA ENDOVASCULAR NTERNATIONAL CONGRESS ENDOVASCULAR CHAPTER SURGERY · 2019-11-09 · Congress of the Endovascular Surgery Chapter, which will take place in Oviedo from November

CIRUGÍA ENDOVASCULAR NTERNATIONAL CONGRESS ENDOVASCULAR CHAPTER SURGERY · 2019-11-09 · Congress of the Endovascular Surgery Chapter, which will take place in Oviedo from November

and Endovascular Surgery Hellenic Journal of Vascular and ......Hellenic Journal of Vascular and Endovascular Surgery Volume 1 Issue 2 April 2019 ISSN 1106-7237 Hellenic Society of

and Endovascular Surgery Hellenic Journal of Vascular and ......Hellenic Journal of Vascular and Endovascular Surgery Volume 1 Issue 2 April 2019 ISSN 1106-7237 Hellenic Society of

Vascular Surgery Back to Basics Dr. George E. Hajjar Vascular and Endovascular Surgery The Ottawa Hospital.

Vascular Surgery Back to Basics Dr. George E. Hajjar Vascular and Endovascular Surgery The Ottawa Hospital.

Mid- and Long-Term Effects of Endovascular Surgery and ...downloads.hindawi.com/journals/bmri/2019/3247615.pdf · Mid- and Long-Term Effects of Endovascular Surgery and Hybrid Procedures

Mid- and Long-Term Effects of Endovascular Surgery and ...downloads.hindawi.com/journals/bmri/2019/3247615.pdf · Mid- and Long-Term Effects of Endovascular Surgery and Hybrid Procedures

Prasad Jetty MD* * Division of Vascular and Endovascular Surgery

Prasad Jetty MD* * Division of Vascular and Endovascular Surgery

Endovascular Surgery

Endovascular Surgery

Endovascular Surgery and Devices978-981-10-8270... · 2018. 8. 8. · v This book is a much-needed and excellent addition to the fields of endovascular treatments, vascular surgery,

Endovascular Surgery and Devices978-981-10-8270... · 2018. 8. 8. · v This book is a much-needed and excellent addition to the fields of endovascular treatments, vascular surgery,

Endovascular Treatment of the Ascending Aorta: is this the Last … · 2019-11-28 · Endovascular Surgery. Thoracic Endovascular Repair. DOI: 10.21470/1678-9741-2019-0317 1Departamento

Endovascular Treatment of the Ascending Aorta: is this the Last … · 2019-11-28 · Endovascular Surgery. Thoracic Endovascular Repair. DOI: 10.21470/1678-9741-2019-0317 1Departamento

Endovascular and Hybrid Therapies for Structural Heart and ... › download › 0003 › 7447 › ... · – Hybrid Endovascular Aortic Arch Surgery – Technique of Thoracic Endografting

Endovascular and Hybrid Therapies for Structural Heart and ... › download › 0003 › 7447 › ... · – Hybrid Endovascular Aortic Arch Surgery – Technique of Thoracic Endografting

Starting endovascular surgery in third world countries

Starting endovascular surgery in third world countries

Anatomy of the Callosomarginal Artery Applications to Microsurgery and Endovascular Surgery

Anatomy of the Callosomarginal Artery Applications to Microsurgery and Endovascular Surgery

Mid- and Long-Term Effects of Endovascular Surgery and ...

Mid- and Long-Term Effects of Endovascular Surgery and ...

Branched Endovascular Repair for Thoracoabdominal ... · Branched endovascular aneurysm repair (BEVAR) is the endoluminal alternative to conventional surgery for thoraco-abdominal

Branched Endovascular Repair for Thoracoabdominal ... · Branched endovascular aneurysm repair (BEVAR) is the endoluminal alternative to conventional surgery for thoraco-abdominal

University of Massachusetts Vascular and Endovascular ... · PDF fileUniversity of Massachusetts Vascular and Endovascular Surgery Integrated Residency Program 2012

University of Massachusetts Vascular and Endovascular ... · PDF fileUniversity of Massachusetts Vascular and Endovascular Surgery Integrated Residency Program 2012

CURRICULUM VITA - mvasrc.mums.ac.ir · 2010 Fellowship of Endovascular Interventions Leipzig –Germany. 2004 Traveling Observership in Vascular Surgery and Endovascular Interventions

CURRICULUM VITA - mvasrc.mums.ac.ir · 2010 Fellowship of Endovascular Interventions Leipzig –Germany. 2004 Traveling Observership in Vascular Surgery and Endovascular Interventions

Louis L. Nguyen, MD, MBA, MPH Division of Vascular & Endovascular Surgery

Louis L. Nguyen, MD, MBA, MPH Division of Vascular & Endovascular Surgery

Vascular Program - Vascular & Endovascular Surgery

Vascular Program - Vascular & Endovascular Surgery