Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a...

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Transcript of Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a...

Page 1: Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.
Page 2: Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.
http://www.bbc.co.uk/education/asguru/biology/02biologicalmolecules/01proteins/11enzymes/03enzymes_b/index.shtml
Page 3: Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.
Page 4: Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.
Page 5: Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.
Page 6: Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.

Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.

Page 7: Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.
Page 8: Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.
Page 9: Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.

AB

CD

Enzyme-substrate reactionCompetitive inhibitionNon-competitive inhibitionCo-factor

Page 10: Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.

What would the effect of each of these conditions be on the activity of an enzyme?Increasing temperature within the normal rangeDecreasing pHDecreasing substrate concentrationIncreasing enzyme concentrationIncreasing concentration of a non-competitive inhibitorIncrease in the surface area of substrateDecreasing concentration of a competitive inhibitorAn increase of temperature above normal limitsAn increase in product concentrationThe activity of a different enzyme

Page 11: Draw sketch graphs for enzyme activity with a competitive inhibitor present and for a non-competitive inhibitor present.

dysregulated in checkpoint inhibitor...is termed checkpoint inhibitor pneumonitis (CIP) (4, 5). Clinical-ly, patients with CIP present with acute to subacute onset of dys-pnea, hypoxemia,

dysregulated in checkpoint inhibitor...is termed checkpoint inhibitor pneumonitis (CIP) (4, 5). Clinical-ly, patients with CIP present with acute to subacute onset of dys-pnea, hypoxemia,

The BTK Inhibitor ARQ 531 Targets Ibrutinib-Resistant CLL ... · ARQ 531 Is a Potent Inhibitor of BCR Signaling ARQ 531 was designed as a reversible, orally bioavailable, ATP-competitive

The BTK Inhibitor ARQ 531 Targets Ibrutinib-Resistant CLL ... · ARQ 531 Is a Potent Inhibitor of BCR Signaling ARQ 531 was designed as a reversible, orally bioavailable, ATP-competitive

Agent Banking Operations as a Competitive Strategy of ... · International Journal of Business ... advantage since the changes present both opportunities and challenges, ... Competitive

Agent Banking Operations as a Competitive Strategy of ... · International Journal of Business ... advantage since the changes present both opportunities and challenges, ... Competitive

Drug Delivery Systems Understanding the Competitive …fletchercsi.com/wp-content/uploads/2018/03/Drug...•Dual chamber pen injectors •Insulin pens •First TNF inhibitor auto-injectors

Drug Delivery Systems Understanding the Competitive …fletchercsi.com/wp-content/uploads/2018/03/Drug...•Dual chamber pen injectors •Insulin pens •First TNF inhibitor auto-injectors

New Anesthesia Drugs - MemberClicks era... · 2017. 7. 21. · New to Ortho World A competitive inhibitor of plasminogen, and in high concentrations a non-competitive inhibitor of

New Anesthesia Drugs - MemberClicks era... · 2017. 7. 21. · New to Ortho World A competitive inhibitor of plasminogen, and in high concentrations a non-competitive inhibitor of

Essentials of Biology - Green River Collegeinstruction.greenriver.edu/kmarr/Biology100/Lectures/1_Student... · 4/21/2011 7 Another kind of inhibitor Competitive Inhibitors • Attach

Essentials of Biology - Green River Collegeinstruction.greenriver.edu/kmarr/Biology100/Lectures/1_Student... · 4/21/2011 7 Another kind of inhibitor Competitive Inhibitors • Attach

Examples of Competitive Inhibitors - BIOLOGY FOR · PDF fileExamples of a Non-competitive Inhibitor (Allosteric) Strychnine Is a colorless highly toxic alkaloid that causes muscular

Examples of Competitive Inhibitors - BIOLOGY FOR · PDF fileExamples of a Non-competitive Inhibitor (Allosteric) Strychnine Is a colorless highly toxic alkaloid that causes muscular

Module Three Analyzing a Company’s Resources and Competitive Position Evaluating a Company’s present strategy. 1.

Module Three Analyzing a Company’s Resources and Competitive Position Evaluating a Company’s present strategy. 1.

Types of Inhibition: Competitive Noncompetitive ...hcchm001/5enzyme.pdf · This reaction with the suicide inhibitor removes active enzyme from the system; this removal is measured

Types of Inhibition: Competitive Noncompetitive ...hcchm001/5enzyme.pdf · This reaction with the suicide inhibitor removes active enzyme from the system; this removal is measured

Naphthoquinone-mediatedInhibitionofLysine ...Conclusion: PTK1 is a reversible, non-competitive inhibitor of p300 KAT activity with reduced toxicity. Significance: These studies provide

Naphthoquinone-mediatedInhibitionofLysine ...Conclusion: PTK1 is a reversible, non-competitive inhibitor of p300 KAT activity with reduced toxicity. Significance: These studies provide

Study on the Present Competitive Performance and Future ... on the Present Competitive Performance... · Study on the Present Competitive Performance and ... Survey the RBS alumni

Study on the Present Competitive Performance and Future ... on the Present Competitive Performance... · Study on the Present Competitive Performance and ... Survey the RBS alumni

SK-216, an Inhibitor of Plasminogen Activator Inhibitor-1 ... · Small Molecule Therapeutics SK-216, an Inhibitor of Plasminogen Activator Inhibitor-1, Limits Tumor Progression and

SK-216, an Inhibitor of Plasminogen Activator Inhibitor-1 ... · Small Molecule Therapeutics SK-216, an Inhibitor of Plasminogen Activator Inhibitor-1, Limits Tumor Progression and

Mechanisms of enzyme inhibition Competitive inhibition: the inhibitor (I) binds only to the active site. EI ↔ E + I Non-competitive inhibition: binds to.

Mechanisms of enzyme inhibition Competitive inhibition: the inhibitor (I) binds only to the active site. EI ↔ E + I Non-competitive inhibition: binds to.

Calbiochem Inhibitor Sourcebook - Merck No Pricewolfson.huji.ac.il/purification/PDF/Protease_Inhibitors/CALBIOCHEM... · Calbiochem Inhibitor SourceBook Inhibitor SourceBook™ Your

Calbiochem Inhibitor Sourcebook - Merck No Pricewolfson.huji.ac.il/purification/PDF/Protease_Inhibitors/CALBIOCHEM... · Calbiochem Inhibitor SourceBook Inhibitor SourceBook™ Your

Kelompok 3. Enzyme Inhibitor Pengertian ; Inhibitor Inhibitor

Kelompok 3. Enzyme Inhibitor Pengertian ; Inhibitor Inhibitor

Competitive Inhibitor of3-hydroxy-3-methylglutarl

Competitive Inhibitor of3-hydroxy-3-methylglutarl

Inhibition of renin activity by aliskiren ameliorates diabetic ... · the first renin inhibitor approved for clinical use, is a small molecule competitive inhibitor that specifically

Inhibition of renin activity by aliskiren ameliorates diabetic ... · the first renin inhibitor approved for clinical use, is a small molecule competitive inhibitor that specifically

Cox inhibitor

Cox inhibitor

Strategic R&D Management as Competitive Strength With Respect to Present and Future Perspective.

Strategic R&D Management as Competitive Strength With Respect to Present and Future Perspective.

Amiloride Is a Competitive Inhibitor of Coxsackievirus B3 RNA Polymerase

Amiloride Is a Competitive Inhibitor of Coxsackievirus B3 RNA Polymerase