Doctor, I am depressed, and sad. What do I have doctor ? Please tell me.

Doctor I am depressed and sad What do I have doctor Please tell me

You have depression

Gee ndash isnrsquot that what I just told you


Canrsquot you give me any added value

Doctor my stomach hurts What do I have doctor Please tell me

You have gastritis


You have gastritis

Doctor I am depressed and sad What do I have doctorPlease tell me

You have depression

Doctor my stomach hurts What do I have doctorPlease tell me

You have gastritis


You have depression

Place in the body

What happened to it

It is infected

How to treat itAntibiotics


You have gastritis


You have depression

Place in the body

What happened to itIt is infected


Gastroenteritis

Gastroenterologist

Mitral Valve Prolapse

Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis

Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis

Medicine = Etiological DiagnosisPsychiatry = Descriptive Diagnosis

SPACE

PsychosisMoodAnxiety

Psychosisdue to injuries etc

Negative symptomsDeficiency

Positive symptoms

delirium

Schizophrenia

Depression Mania

Reactive Secondary

Endogenous Major

Mixed anxiety and depression

Psychosis Depression

ManiaPsychosis

Schizoaffective disorder

Generalized

Phobia

Personality disorders

Learning disability

OCD

PTSD

Eating disorders

ldquo hellip

we are at the epicycle stage of psychiatry

where astronomy was before Copernicus

and biology before Darwin

helliprdquo

Neuroscience Phenomenology

Enormous gapThe clinician sees a patient

not neuronal networks or neurotransmitters

Why we failed

Proposed RDoC

Clinical Brain ProfilingCBP


Explanatory power


Translation matrix

Neuroscience Phenomenology Sign 1Sign 2Sign 3Sign 4Sign 5Sign 6Sign N

Symptom 1Symptom 2Symptom 3Symptom 4Symptom 5Symptom N

Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization

Constrain frustration

Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN

Psychosis Disconnection

Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN

Clinical Brain Profiling

CBP

Based on Literature Publications

Based on Neural

network simulations

Based on 20 years of

theoretical work

Sign 1Sign 2Sign 3Sign 4Sign 5Sign 6Sign N


Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP

Predicted disturbance

CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5

Cardiac Insufficiency

Brain Insufficiency

Diagnose

Diagnose

Algorithm of Disturbance

Correct with Pacemaker


Correct with Brain Pacemaker


Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties

One neuron has no awareness or feelings but many organized neurons do

The whole is more than the sum of its parts

1010)107(

Emergent Properties



1010)107(

Marcel Mesulam

From sensation to cognition Mesulam 1998

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Stanislav Dehene 2006

1010)107(

Marcel Mesulam



Giulio Tononi

UnitaryUndividable 2-3s

Taps into large repertoireStatistical combinations

One of billion others thus dramatically reduces uncertainty

Information = reduction of uncertainty (entropy) thus Can be quantified with Information measurements

Ф = (info in whole) measures

complexes

Bernard Baars 1980s

Emergent Properties



To make as perfect or effective as possible

Optimization

To find the best compromise among several often conflicting requirements


Optimization


Small World Network

Clustering Coefficient = Measure of density of connections between nearest neighbors

Path length = inversely related to global efficacy of parallel information transfer

Small-worldness = high clustering small path lengthcomparable to random graph

Hierarchy = Hubs with many long distance connections and few local connections

Rent exponent = topo-physical embedment in physical space of the network scaling relationships

Mean connection distance = Euclidean distance between centers in stereotactic space

Assortativity = measures the preference of a node to connect to other nodes of similar degree

Node = cortical region or neuron

Edge = statistical measure of association

Degree = the number of edges connecting a node

Specific

Neuroscientific

consideration

[DDMN]

Disturbance to the default mode network

[DMDd]

Disturbance to Matching dynamics Deoptimization type

[DMDo]

Disturbance to Matching dynamics Optimization type

[DMCO]

Disturbance to Multiple constrain organization

[ibDMCO]

Input bound Disturbance to Multiple constrain organization

[DD]

Disconnection Dynamics

[OD]

Over-connection Dynamics

[TDS]

Top down shift

[BUI]

Bottom-upInsufficiency

Signs Signs Signs Signs Signs Signs Signs Signs Signs Signs Signs Signs Signs Signs

Symptoms Symptoms Symptoms Symptoms Symptoms Symptoms Symptoms Symptoms Symptoms Symptoms Symptoms History History History History History History History History History History

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




Theodore Meynert(1833-1892)

EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

EGO Experience dependent plasticity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

EGO=Default mode network


Internal Representations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers

Otto Kernberg1928 1990

Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

Personality amp Personality Disorders

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

De-optimization Optimization

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

Multiple constraint frustration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis Negative (restriction)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations

History of delusions

depressed

Complains of depressed mood

History of depression

Complains of Confused thoughts

Signs

Symptoms

History

Translation of signs and

symptoms to presumed

brain disturbances

Testable predictions

Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History

Is it as good as scales

Is it good as consensual

current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




Wolf RC Sambataro F Vasic N

Schmid M Thomann PA

Bienentreu SD Wolf ND Aberrant connectivity of resting-

state networks in borderline

personality disorder J Psychiatry

Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

Congdon E Mumford JA Cohen JR Galvan A

Aron AR Xue G Miller E Poldrack RA

Engagement of large-scale networks is

related to individual differences in inhibitory

control Neuroimage 2010 Nov 153(2)653-

63 Epub 2010 Jun 30

Monk CS Nelson EE Woldehawariat G

Montgomery LA Zarahn E McClure EB

Guyer AE Leibenluft E Charney DS Ernst M

Pine DS Experience-dependent plasticity for

attention to threat Behavioral and neurophysiological evidence in humans Biol

Psychiatry 2004 Oct 1556(8)607-10

Volkow ND Tomasi D Wang GJ

Fowler JS Telang F Goldstein RZ

Alia-Klein N Woicik P Wong C Logan

J Millard J Alexoff D

Positive emotionality is associated

with baseline metabolism in

orbitofrontal cortex and in regions of

the default network

Mol Psychiatry 2011 Apr 12

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




J Neurosci 2010 Nov 2430(47)15915-26Aberrant frontal and temporal complex network structure in

schizophrenia a graph theoretical analysisvan den Heuvel MP Mandl RC Stam CJ Kahn RS Hulshoff Pol HE our findings suggest that schizophrenia patients have a less strongly globally integrated structural brain network with a reduced central role for key frontal hubs resulting in a limited structural capacity to integrate information across brain regions



Yu Q Sui J Rachakonda S He H Pearlson G Calhoun VD Altered small-world brain networks in temporal lobe in patients with schizophrenia performing an auditory oddball task Front Syst Neurosci 2011 Feb 857

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









Pettersson-Yeo W Allen P Benetti S McGuire P

Mechelli A Dysconnectivity in schizophrenia

Where are we now Neurosci Biobehav Rev

2011 Apr35(5)1110-24 Epub 2010 Nov

27Review

Jones MW Errant ensembles dysfunctional neuronal network dynamics in schizophrenia Biochem Soc Trans 2010 Apr38(2)516-21 Review

Bassett DS Bullmore E Verchinski BA Mattay VS Weinberger DR Meyer-Lindenberg A Hierarchical organization of human cortical networks in health and schizophrenia J Neurosci 2008 Sep 1028(37)9239-48

Bodnar M Harvey PO Malla AK Joober R

Lepage M The parahippocampal gyrus as a

neural marker of early remission in first-

episode psychosis a voxel-based

morphometry study Clin Schizophr Relat

Psychoses 2011 Jan4(4)217-28

Guye M Bettus G Bartolomei F

Cozzone PJ Theoretical analysis of

structural and functional connectivity

MRI in normal and pathological brain

networks MAGMA 2010 Dec23(5-

6)409-21 Epub 2010 Mar 27Graph

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




Nissen C Holz J Blechert J Feige B Riemann D Voderholzer U Normann C Learning as a model for neural plasticity in major depression Biol Psychiatry 2010 Sep 1568(6)544-52

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


Central Executive Network

DefaultModeNetwork

SalienceNetwork

[DD]Disconnection Dynamics

[OD]Over-connection Dynamics

[BUI]Bottom-up

Insufficiency

[TDS]Top down shift

[DMDd]Disturbance to Matching dynamics

Deoptimization type

[DMDo]Disturbance to Matching dynamics

Optimization type

[DDMN]Disturbance to the default mode

network

NeuroAnalysis Validation

Clinical phenomena

Network disturbances How to detect diagnose amp monitor


Disturbances to development of default mode network

Age-related changes resting-state functional connectivity MRI (rs-fcMRI) (Van Dijk KR et al 2010) Age related Matching complexity Free energy estimations Entropy measurements integrated information theory

Mood amp AnxietyDisturbances to Optimization dynamics

Short-term over time Dynamics of Matching complexity Free energy estimations Entropy measurements integrated information theory

Schizophrenia delusions and abolition

Hierarchal (top-down bottom-up) disorders

Small world network analysis for hub composition Estimating hierarchy k-shell decomposition percolation theory and fractal geometry

Schizophrenia Disorganization deficiency

Connectivity imbalancesDisconnection over-connection

Correlations Synchrony Granger causality Mutual information Dimension estimation Bayesian statistics Dynamic Causal Modeling Independent components analysis Neural complexity (Correlation matrix) overall Small world network analysis


Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

N e u r o A n a l y s I sneuroanalysisorgil

Slide 1

Slide 2

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Slide 81

You have depression





You have gastritis


You have gastritis


You have depression


You have gastritis


You have depression

Place in the body

What happened to it

It is infected



You have gastritis


You have depression

Place in the body



Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis

Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis


SPACE




Positive symptoms

delirium

Schizophrenia

Depression Mania

Reactive Secondary

Endogenous Major



ManiaPsychosis


Generalized

Phobia


Learning disability

OCD

PTSD

Eating disorders

ldquo hellip




helliprdquo




Why we failed

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81





You have gastritis


You have gastritis


You have depression


You have gastritis


You have depression

Place in the body

What happened to it

It is infected



You have gastritis


You have depression

Place in the body



Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis

Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis


SPACE




Positive symptoms

delirium

Schizophrenia

Depression Mania

Reactive Secondary

Endogenous Major



ManiaPsychosis


Generalized

Phobia


Learning disability

OCD

PTSD

Eating disorders

ldquo hellip




helliprdquo




Why we failed

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81


You have gastritis


You have depression


You have gastritis


You have depression

Place in the body

What happened to it

It is infected



You have gastritis


You have depression

Place in the body



Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis

Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis


SPACE




Positive symptoms

delirium

Schizophrenia

Depression Mania

Reactive Secondary

Endogenous Major



ManiaPsychosis


Generalized

Phobia


Learning disability

OCD

PTSD

Eating disorders

ldquo hellip




helliprdquo




Why we failed

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81


You have gastritis


You have depression

Place in the body

What happened to it

It is infected



You have gastritis


You have depression

Place in the body



Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis

Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis


SPACE




Positive symptoms

delirium

Schizophrenia

Depression Mania

Reactive Secondary

Endogenous Major



ManiaPsychosis


Generalized

Phobia


Learning disability

OCD

PTSD

Eating disorders

ldquo hellip




helliprdquo




Why we failed

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81


You have gastritis


You have depression

Place in the body



Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis

Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis


SPACE




Positive symptoms

delirium

Schizophrenia

Depression Mania

Reactive Secondary

Endogenous Major



ManiaPsychosis


Generalized

Phobia


Learning disability

OCD

PTSD

Eating disorders

ldquo hellip




helliprdquo




Why we failed

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis

Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis


SPACE




Positive symptoms

delirium

Schizophrenia

Depression Mania

Reactive Secondary

Endogenous Major



ManiaPsychosis


Generalized

Phobia


Learning disability

OCD

PTSD

Eating disorders

ldquo hellip




helliprdquo




Why we failed

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

Gastroenteritis

Gastroenterologist


Cardiologist

Urologist

Depression

Psychiatrist

Glomerulonephritis


SPACE




Positive symptoms

delirium

Schizophrenia

Depression Mania

Reactive Secondary

Endogenous Major



ManiaPsychosis


Generalized

Phobia


Learning disability

OCD

PTSD

Eating disorders

ldquo hellip




helliprdquo




Why we failed

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81


SPACE




Positive symptoms

delirium

Schizophrenia

Depression Mania

Reactive Secondary

Endogenous Major



ManiaPsychosis


Generalized

Phobia


Learning disability

OCD

PTSD

Eating disorders

ldquo hellip




helliprdquo




Why we failed

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81




Positive symptoms

delirium

Schizophrenia

Depression Mania

Reactive Secondary

Endogenous Major



ManiaPsychosis


Generalized

Phobia


Learning disability

OCD

PTSD

Eating disorders

ldquo hellip




helliprdquo




Why we failed

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

ldquo hellip




helliprdquo




Why we failed

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81




Why we failed

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

Proposed RDoC



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81



Explanatory power


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81


Translation matrix



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


Syndrome



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


Based on Neural

network simulations


theoretical work



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81



Cs Disconnection

Ci Over connection

De-optimization

Hyper-optimization


Disturbed DMN


CBP


CF(b) = 2

DMN =5

Cs =10

Ci =3

Hbu =7

Htd =1

D = 13

O =0

CF =5


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81


Brain Insufficiency

Diagnose

Diagnose






Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

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Slide 20

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Slide 30

Slide 31

Slide 32

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Slide 38

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Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

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Slide 65

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Slide 67

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Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81


Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

General

Neuroscientific

consideration

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

Emergent Properties



1010)107(

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

Emergent Properties



1010)107(

Marcel Mesulam


Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

Emergent Properties



1010)107(

Marcel Mesulam


Bernard Baars 1980s


1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

1010)107(

Marcel Mesulam



Giulio Tononi






complexes

Bernard Baars 1980s

Emergent Properties




Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81


Optimization



Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81


Optimization


Small World Network











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81











Specific

Neuroscientific

consideration

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





EGO

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

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Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

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Slide 23

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Slide 25

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Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations

Psychosis

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Donald Hebb 1948

Carl Rogers


Hinz Kohut1913-1981




Object relations

psychology


Karl Friston

FreeEnergy

Giulio Tononi

Matching complexity


Depression

Elevated moodMania


Anxiety

Herbert Simon

1962

Marcel Mesulam

Negative

symptoms

Loosening

associations

Perseverations

Delusions


Negative (volition)

Delusional

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



brain disturbances


Validation

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]


Delusions

Hallucinations


depressed




Signs

Symptoms

History



current descriptive

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81


Donald Hebb 1948




[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network


[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

Slide 6

Slide 7

Slide 8

Slide 9

Slide 10

Slide 11

Slide 12

Slide 13

Slide 14

Slide 15

Slide 16

Slide 17

Slide 18

Slide 19

Slide 20

Slide 21

Slide 22

Slide 23

Slide 24

Slide 25

Slide 26

Slide 27

Slide 28

Slide 29

Slide 30

Slide 31

Slide 32

Slide 33

Slide 34

Slide 35

Slide 36

Slide 37

Slide 38

Slide 39

Slide 40

Slide 41

Slide 42

Slide 43

Slide 44

Slide 45

Slide 46

Slide 47

Slide 48

Slide 49

Slide 50

Slide 51

Slide 52

Slide 53

Slide 54

Slide 55

Slide 56

Slide 57

Slide 58

Slide 59

Slide 60

Slide 61

Slide 62

Slide 63

Slide 64

Slide 65

Slide 66

Slide 67

Slide 68

Slide 69

Slide 70

Slide 71

Slide 72

Slide 73

Slide 74

Slide 75

Slide 76

Slide 77

Slide 78

Slide 79

Slide 80

Slide 81

[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]









[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

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[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]












2011 Apr35(5)1110-24 Epub 2010 Nov

27Review















[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


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[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]





[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

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[DDMN]


[DMDd]


[DMDo]


[DMCO]


[ibDMCO]


[DD]


[OD]


[TDS]

Top down shift

[BUI]













2011 Apr35(5)1110-24 Epub 2010 Nov

27Review
















Schmid M Thomann PA




Neurosci 2011 Mar

136(2)100150






63 Epub 2010 Jun 30






Psychiatry 2004 Oct 1556(8)607-10








the default network



DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

Slide 4

Slide 5

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Slide 81


DefaultModeNetwork

SalienceNetwork



[BUI]Bottom-up

Insufficiency

[TDS]Top down shift


Deoptimization type


Optimization type


network


Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

Slide 2

Slide 3

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Clinical phenomena














Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


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Brain Insufficiency

Diagnose

Diagnose





Phenomenology

Brain disturbance


Slide 1

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Doctor, I am depressed, and sad. What do I have doctor ? Please tell me.

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Transcript of Doctor, I am depressed, and sad. What do I have doctor ? Please tell me.