DISCONTOOLS- a method to prioritize animal health research in the E.U.
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DISCONTOOLS- a method to prioritize animal health research in the E.U.
Johannes Charlier, DISCONTOOLS Project Manager
4th September, 2014
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Summary• DISCONTOOLS
– Origin– Questions tackled– The database– Global hub for disease prioritisation in terms of
research needs– Work Programme
• Conclusions
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ETPGAH – Vision to Action Plan
August 2005 May 2006 July 2007
Stakeholders, led by industry, come together
to agree on a common
vision for the technology
Stakeholders, define a
Strategic Research Agenda setting the necessary
mid- to longterm objectives
Stakeholders, implement the
Strategic ResearchAgenda with the mobilisation of
significant humanand financial
resources
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Framework Programme 7
Coordination of Funding
April 2008 - 45 months €997,218
Feb 2011 - 48 months €999,130
Jan 2012 - 48 months €2m
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Background• DISCONTOOLS was a Stakeholder driven project
– All European & Global Stakeholders welcomed to join
• 5 Year Project - March, 2008 to February, 2013• Output
– Disease database – 52 diseases– Gap analysis for each disease– Prioritisation model on public website– Methodology to identify & deploy new research
technologies in the animal health research world
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Questions Tackled• How do we decide where to spend scarce
research resources?• Which diseases?• Which gap(s) in each disease?• Priority of whom?
– Research community?– Funders of research?– People at coal face – CVO, Vet, Farmer?– Industry?
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www.discontools.eu
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The disease database
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View disease info – control tools
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Disease scoring criteria
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Gap analysis – Diagnostics, vaccines, pharmaceuticals
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Sample report – all diseases ranked by score
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Prioritisation of Epizootic diseases
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Prioritisation of Zoonotic diseases
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Prioritisation of Food producing diseases
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Achievements & Economics• DISCONTOOLS finished on February 28th, 2013• Built consensus across stakeholders• Focus on critical gaps• Agreement on need to continue• Make best use of €400m from public sector &
€400m from private sector • Hasten the arrival of new diagnostics, vaccines &
pharmaceuticals• Disease burden of 20% on animal production
valued at €141b (in EU) – reduce cost by €28b!
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Continuing DISCONTOOLS Work!• Business case made – need € 100,000 per year• Need 14 countries to fund at € 7000 each• 10 countries/funders have committed to date -
others considering• Held meeting of funders in February, 2014• Sufficient funds to re-launch DISCONTOOLS!
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DISCONTOOLS Work in 2014• Commenced DISCONTOOLS work in June, 2014
– Update existing diseases over time– Add new diseases– Refine & further develop model
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12 diseases in focus - 2014• Existing - AI, ASF, BT, Campylobacter,
Cysticercosis, E. coli, FMD, Nematodes, ParaTB, PRRS, SIV
• New – PEDV• List determined by funders with offer to work on
Cysticercosis & PEDV
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Logistics• Expert Groups formed or being formed ideally
including:– laboratory expertise, an epidemiologist, an
industry representative, a diagnostics expert and an individual with economic/trade expertise
• Documents to be updated:– Disease & Product analysis– Gap Analysis– Prioritisation– 2 page summary
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Conclusions - 1• Public website with searchable database• Stakeholder agreed prioritised research gaps• Research agenda for the future has been
established!• Focus funding on prioritised research gaps
– ANIHWA, Horizon 2020, Countries, Industry, Trusts, Foundations, Charities, etc.
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Conclusions - 2• The work of DISCONTOOLS will continue & evolve
driven especially by funders to meet their needs• We should organise the deployment of € 800
million (3 billion globally) in the best way possible!• The prize of hastening the development of new or
better disease control tools is enormous - €28 billion per year in the EU alone!
• We should make DISCONTOOLS our global hub where we pool our resources
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For more information please consult:
www.discontools.eu
Rue Defacqz, 11000 Brussels, BelgiumTel.: +32 (0)2 543 7570Fax: +32 (0)2 537 0049