DIGITAL PATHOLOGY PLATFORM DEVOTED TO LYMPHOMA · Networking of Digital Microscope Slides •...
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• A State-of-the-Art Equipment for Scanning, Analysis and Networking of Digital Microscope Slides • Platform of the Mondor Institute of Biomedical Research (IMRB) shared between LYSA-LYSARC, IMRB Inserm teams (teams 7 - Pr. Allory and 9 - Pr. Gaulard) and the Medical School of Paris-Est Créteil University • High-capacity slide scanner (loader of 120 slides - ScanScope XT, Aperio –LEICA) • Internet and intranet servers • Software suite for the management of microscope imaging (CalopixWorkstation - TRIBVN): visualization of slides, imaging analyses, morphometry, colorimetry, tissue micro-array analysis, annotations • Collaborative platform of virtual slides sharing with web access (Teleslide – Multimédia and TéléMédecine TRIBVN) • A Platform of Digital Pathology at the Service of LYSA Pathologists, with Varied Applications • Diagnosis: slide review of protocol cases by digital pathology. Requests for advice and prescription of complementary techniques remotely. • Translational research works: high-throughput analysis of tissue micro-array, morphometry, exchanges of results, scientific publications… • Ongoing training of pathologists: collection of slides for sharing and analysis of tough or difficult cases, publications for congresses. DIGITAL PATHOLOGY PLATFORM DEVOTED TO LYMPHOMA A platform developed with funding and means of:
Transcript of DIGITAL PATHOLOGY PLATFORM DEVOTED TO LYMPHOMA · Networking of Digital Microscope Slides •...
• A State-of-the-Art Equipment for Scanning, Analysis and Networking of Digital Microscope Slides • Platform of the Mondor Institute of Biomedical Research (IMRB) shared between LYSA-LYSARC,
IMRB Inserm teams (teams 7 - Pr. Allory and 9 - Pr. Gaulard) and the Medical School of Paris-Est Créteil University
• High-capacity slide scanner (loader of 120 slides - ScanScope XT, Aperio –LEICA)
• Internet and intranet servers
• Software suite for the management of microscope imaging (CalopixWorkstation - TRIBVN): visualization of slides, imaging analyses, morphometry, colorimetry, tissue micro-array analysis, annotations
• Collaborative platform of virtual slides sharing with web access (Teleslide – Multimédia and TéléMédecine TRIBVN)
• A Platform of Digital Pathology at the Service of LYSA Pathologists, with Varied Applications
• Diagnosis: slide review of protocol cases by digital pathology. Requests for advice and prescription of complementary techniques remotely.
• Translational research works: high-throughput analysis of tissue micro-array, morphometry, exchanges of results, scientific publications…
• Ongoing training of pathologists: collection of slides for sharing and analysis of tough or difficult cases, publications for congresses.
DIGITAL PATHOLOGY PLATFORM DEVOTED TO LYMPHOMA
A platform developed with funding and means of:
Automated analysis of nuclear, cytoplasmic or membrane biomarkers (morphometry / colorimetry)
Reading with synchronization of spots
HES CD20 CD5
CD163 immunohistochemistry (in brown)
Automated analysis of CD163 expression on a whole tissue section of Hodgkin lymphoma In blue: not-labelled cells In red: CD163+ cells
Result of automated detection of CD163+ cells (in red)
LYSA Scientific Managers Christiane Copie, Bettina Fabiani, Peggy DartiguesLYSARC Operational Contact Maryse Baia, [email protected], +33(0)1 49 81 37 48 (LYSA-P)
• High-Throughput Analysis on Large Patient CohortsTissue micro-array (TMA) analysis
• Quick antibody screening on a whole cohort• Identification of TMA spots and data associated to virtual
slide (patient identifier, sample location, fixative used…)• Continuous analysis, synchronization of spots allowing
to analyze for the same sample, different biomarkers and to answer a form of interpretation which can be exported to Excel
DIGITAL PATHOLOGY
PLATFORM
DEVOTED
TO LYMPHOMA
HES stained TMA slide
