Diastereoselective Synthesis of Glycosylated Prolines as α-Glucosidase Inhibitors and...

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2007 Carbohydrates U 0500 Diastereoselective Synthesis of Glycosylated Prolines as α-Glucosidase Inhibitors and Organocatalyst in Asymmetric Aldol Reaction. — Tetrasubstituted glycosyl pyrrolidines are diastereoselectively synthesized by 1,3-dipolar cycloaddition of azomethine ylides and glycosyl olefins. The compounds (III), especially derivative (IIIa), show α-glucosidase inhibitory activity. Their catalytic potential in the asymmet- ric aldol reaction is demonstrated. — (PANDEY, J.; DWIVEDI, N.; SINGH, N.; SRIVASTAVA, A. K.; TAMARKAR, A.; TRIPATHI*, R. P.; Bioorg. Med. Chem. Lett. 17 (2007) 5, 1321-1325; Med. Process Chem. Div., Cent. Drug Res. Inst., Lucknow 226 001, India; Eng.) — H. Toeppel 29- 171

Transcript of Diastereoselective Synthesis of Glycosylated Prolines as α-Glucosidase Inhibitors and...

Page 1: Diastereoselective Synthesis of Glycosylated Prolines as α-Glucosidase Inhibitors and Organocatalyst in Asymmetric Aldol Reaction.

2007

CarbohydratesU 0500 Diastereoselective Synthesis of Glycosylated Prolines as α-Glucosidase Inhibitors

and Organocatalyst in Asymmetric Aldol Reaction. — Tetrasubstituted glycosyl pyrrolidines are diastereoselectively synthesized by 1,3-dipolar cycloaddition of azomethine ylides and glycosyl olefins. The compounds (III), especially derivative(IIIa), show α-glucosidase inhibitory activity. Their catalytic potential in the asymmet-ric aldol reaction is demonstrated. — (PANDEY, J.; DWIVEDI, N.; SINGH, N.; SRIVASTAVA, A. K.; TAMARKAR, A.; TRIPATHI*, R. P.; Bioorg. Med. Chem. Lett. 17 (2007) 5, 1321-1325; Med. Process Chem. Div., Cent. Drug Res. Inst., Lucknow 226 001, India; Eng.) — H. Toeppel

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A Highly Diastereoselective ‘Super Silyl’ Governed …...A Highly Diastereoselective ‘Super Silyl’ Governed Aldol Reaction: Synthesis of α,β-Dioxyaldehydes and 1,2,3-Triols

A Highly Diastereoselective ‘Super Silyl’ Governed …...A Highly Diastereoselective ‘Super Silyl’ Governed Aldol Reaction: Synthesis of α,β-Dioxyaldehydes and 1,2,3-Triols

Single multifunctional organocatalyst

Single multifunctional organocatalyst

A concise and diastereoselective total synthesis of cis ... · A concise and diastereoselective total synthesis of cis and trans-pterocarpans Electronic Supplementary Information

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Pyridine is an organocatalyst for the reductive ozonolysis ...

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Enantio- and Diastereoselective Addition of Cyclohexyl ...Enantio- and Diastereoselective Addition of Cyclohexyl ... prior to use. Cyclopentyl methyl ether was additionally ... The

Enantio- and Diastereoselective Addition of Cyclohexyl ...Enantio- and Diastereoselective Addition of Cyclohexyl ... prior to use. Cyclopentyl methyl ether was additionally ... The

Chiral Biphenylamide Derivative: An Efficient Organocatalyst ...Chiral Biphenylamide Derivative: An Efficient Organocatalyst for the Enantioselective Synthesis of ... (C) General procedure

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Organocatalytic Enantio- and Diastereoselective Synthesis ... · PDF fileSI-1 Organocatalytic Enantio- and Diastereoselective Synthesis of 3,5-Disubstituted Prolines Iker Riaño, Estibaliz

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Diastereoselective Construction of Remote Stereocenters ...evans.rc.fas.harvard.edu/pdf/smnr_2001-2002_Peterson_Scott.pdf · Diastereoselective Construction of Remote Stereocenters:

Diastereoselective Construction of Remote Stereocenters ...evans.rc.fas.harvard.edu/pdf/smnr_2001-2002_Peterson_Scott.pdf · Diastereoselective Construction of Remote Stereocenters:

1,3‐Diamine‐Derived Bifunctional Organocatalyst Prepared ... · 1,3-Diamine-Derived Bifunctional Organocatalyst Prepared from Camphor ... [12f] Camphor is one of ... These are

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Heterogeneously Catalyzed Diastereoselective Synthesis of 2 ...work-up and leads to the diastereoselective formation of the (R,R)-and (S,S)-isomers. Thesolid-state structures of 4a,

Heterogeneously Catalyzed Diastereoselective Synthesis of 2 ...work-up and leads to the diastereoselective formation of the (R,R)-and (S,S)-isomers. Thesolid-state structures of 4a,

ONE-POT DIASTEREOSELECTIVE SYNTHESIS OF CHIRAL … · Vol. 43, No. 1 One-pot diastereoselective synthesis of chiral tricyclic l-cysteine and d-penicillamine derivatives 125 The purpose

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Prolines Profile : Web Design & Graphic Design in Saudi Arabia

Prolines Profile : Web Design & Graphic Design in Saudi Arabia

Introduction of two prolines and removal of the polybasic ...Sep 16, 2020  · 1 1 Introduction of two prolines and removal of the polybasic cleavage site leads to 2 optimal efficacy

Introduction of two prolines and removal of the polybasic ...Sep 16, 2020  · 1 1 Introduction of two prolines and removal of the polybasic cleavage site leads to 2 optimal efficacy

Concise strategy for diastereoselective annulation to ...

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Diastereoselective synthesis of novel aza ...

Diastereoselective synthesis of novel aza ...

Diastereoselective Synthesis of Protected Syn 1,3-Diols by ...evans.rc.fas.harvard.edu/pdf/evans166.pdf · Diastereoselective Synthesis of Protected Syn 1,3-Diols by Base-Catalyzed

Diastereoselective Synthesis of Protected Syn 1,3-Diols by ...evans.rc.fas.harvard.edu/pdf/evans166.pdf · Diastereoselective Synthesis of Protected Syn 1,3-Diols by Base-Catalyzed

Diastereoselective Piperidine Synthesis through DDQ ...d-scholarship.pitt.edu/8895/1/Brizgys_Gediminas_J... · Diastereoselective Piperidine Synthesis through DDQ-Mediated Oxidative

Diastereoselective Piperidine Synthesis through DDQ ...d-scholarship.pitt.edu/8895/1/Brizgys_Gediminas_J... · Diastereoselective Piperidine Synthesis through DDQ-Mediated Oxidative

6 Copper-mediated Diastereoselective Conjugate Addition ...traxanh.free.fr/Download/Modern Organocopper Chemistry/Chapter6... · Copper-mediated Diastereoselective Conjugate Addition

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Highly Diastereoselective and Enantioselective Olefin ...

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Diastereoselective synthesis of chiral 1,3 …...When using a non-chiral organocatalyst, such as pyrrolidine, 5, cyclohexadienal 4 was obtained in low yields, although without diastereoselectivity

Diastereoselective synthesis of chiral 1,3 …...When using a non-chiral organocatalyst, such as pyrrolidine, 5, cyclohexadienal 4 was obtained in low yields, although without diastereoselectivity