Diagnostic Strategy and Risk Assessment …540525,en.pdf · Diagnostic Strategy and Risk Assessment...
1
REMEDIATE Diagnostic Strategy and Risk Assessment Framework for Complex Chemical Mixtures Sabrina Cipullo School of Energy, Environment and Agrifood, Cranfield University Supervisors: Dr Frederic Coulon, Dr George Prpich 1. Background Environmental contaminations often comprise a complex of chemical contaminants both organic and inorganic. Understanding the distribution, behaviour and interaction of these mixtures provides the necessary evidence for supporting a robust remediation strategy. Risk assessments are used to guide management strategies, however the exposure assessments embedded within them do not explicitly address the partitioning and bioavailability of chemical mixtures. This inability may contribute to an overestimation of both the eco toxicological effects of the fractions and their mobility, leading to an overestimation of health effects. 2. Aims of the research project 1. Investigating factors affecting contaminants concentration 2. Predicting fate and persistence of complex chemical mixtures 3. Defining end point and linking bioavailability to toxicity changes 4. Connect all the findings to deliver an integrated risk assessment framework 3. Objectives • Study the effects of different environmental conditions on the recovery of contaminants in soil • Predict the fate of complex chemical mixtures in soil • Study the transport of complex chemical mixtures (e.g. leaching, co-solvency) • Investigate toxicity changes through different bioassay techniques 4. Experimental design 5. Project deliverables and novelty • Provide a correct estimation of the likely presence of contaminants in soil • Moving forward in respect to total contaminant concentration approach • Develop a fugacity based environmental fate model • Investigate metals transport model • Provide better evaluation of the bioavailable fractions • Improve assumptions about bioavailability/toxicity over time based on initial evaluations For further details please free to contact us at: s.cipullo f.coulon or g.prpich (@cranfield.ac.uk)
Transcript of Diagnostic Strategy and Risk Assessment …540525,en.pdf · Diagnostic Strategy and Risk Assessment...
REMEDIATE
Diagnostic Strategy and Risk Assessment Framework for Complex Chemical Mixtures
Sabrina Cipullo School of Energy, Environment and Agrifood, Cranfield University Supervisors: Dr Frederic Coulon, Dr George Prpich
1. Background
Environmental contaminations often comprise a complex of chemical contaminants both organic and inorganic. Understanding the distribution, behaviour and interaction of these mixtures provides the necessary evidence for supporting a robust remediation strategy. Risk assessments are used to guide management strategies, however the exposure assessments embedded within them do not explicitly address the partitioning and bioavailability of chemical mixtures. This inability may contribute to an overestimation of both the eco toxicological effects of the fractions and their mobility, leading to an overestimation of health effects.
2. Aims of the research project
1. Investigating factors affecting contaminants concentration 2. Predicting fate and persistence of complex chemical mixtures 3. Defining end point and linking bioavailability to toxicity changes 4. Connect all the findings to deliver an integrated risk assessment
framework
3. Objectives
• Study the effects of different environmental conditions on the recovery of contaminants in soil
• Predict the fate of complex chemical mixtures in soil • Study the transport of complex chemical mixtures (e.g.
leaching, co-solvency) • Investigate toxicity changes through different bioassay
techniques 4. Experimental design
5. Project deliverables and novelty
• Provide a correct estimation of the likely presence of contaminants in soil
• Moving forward in respect to total contaminant concentration approach
• Develop a fugacity based environmental fate model • Investigate metals transport model • Provide better evaluation of the bioavailable fractions • Improve assumptions about bioavailability/toxicity
over time based on initial evaluations
For further details please free to contact us at: s.cipullo f.coulon or g.prpich (@cranfield.ac.uk)
