Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben...

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Serving Today and Building Foundations for the Future Annual Report DEPARTMENT OF PAEDIATRICS

Transcript of Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben...

Page 1: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Serving Today and

Building Foundations

for the Future

Annual ReportDepartment of paeDiatrics

Page 2: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

February 2014

This reports includes data and events from the calendar year 2013, and academic year July 2012 – June 2013

Respectfully submitted by: James D. Kellner MD, FRCPC Professor and Head, Department of Paediatrics, University of Calgary and Alberta Health Services – Calgary Zone

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics

Table of Contents

Introduction

Vission, Mission, Values

Department Organization and Leadership

Description of Department Members

Zone Paediatric Executive Committee 2013 Admin, Support and Research Staff

Overview of Clinical Sections and Divisions and Research Units SeCTIONS

Adolescent Medicine

PROGUT

Paediatric Update Conference

Cardiology

Community Peadiatrics

Critical Care

Developmental Peadiatrics

Emergency Medicine

Paediatric Emergency Medicine at the South Health Campus

Endocrinology

Gastroenterology

Hematology

Hospital Pediatrics

KidSIM™ Pediatric Simulation

Infectious Diseases

Medical Genetics

Neonatology

ACH Neonatal Intensive Care Unit (NICU) update | November 2013

Nephrology

Transition Symposium

Neurology

Calgary Childhood Traumatic Brain Injury Program

Oncology

Palliative Medicine

Respiratory

Asthma Program

2

5

6

8

9

10

13 Rheumatology

reSearCH uNITSBehavioural Research Unit

Global Child Health Unit

Research Methods Team

Sleep-Epilepsy Research Project

Dr. Suzanne Tough

Paediatric Clinical Activity in Calgary Zone Facilities

Education and Training ProgramsOvervIew

uNdergraduaTe MedICal eduCaTION (uMe)

POST graduaTe MedICal eduCaTION (PgMe)

PGME Programs and Trainees

General Paediatrics

Medical Genetics

Neurology

Developmental Paediatrics

Emergency Medicine

Endocrinology

Gastroenterology

Hematology

Infectious Diseases

58

77

1

91

99

103

119

Neonatal/Perinatial

Nephrology

Respiratory Medicine

CONTINuINg MedICal eduCaTION (CMe)

CME

Undergraduate Health Sciences

Paediatric Simulation Education

Mentorship Program

Awards and RecognitionsMission Possible App

New Department Faculty Members

Research Funding

Peer-Reviewed Research Publications

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Department of paeDiatrics | annual report 20132

Introduction

Welcome to the combined academic

and clinical Department of Paediatrics

for the University of Calgary and

Alberta Health Services – Calgary Zone.

ucalgary.ca/paed/

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 3

Introduction

The Department has four fundamental activities:

1. Provision of all levels of clinical services to infants, children and adolescents in Calgary, throughout Alberta and other provinces;

2. Training the next generation of healthcare professionals caring for children and their families, and continued training for current healthcare professionals;

3. Knowledge generation and innovation in clinical care and education through the conduct, dissemination and translation of research;

4. Provision of leadership throughout clinical and academic health systems.

We have grown to over 300 clinical and academic faculty members in 20 clinical sections and divisions, and 2 academic units. The hub of our clinical services is the 135 bed Alberta Children’s Hospital (www.albertahealthservices.ca/facilities.asp?pid=facility&rid=1010904) which last year (2012-13) received over 296,000 outpatient clinic visits, nearly 73,000 emergency department visits and nearly 7900 admissions. We provide neonatal intensive care unit (NICU) care at the Alberta Children’s Hospital, Foothills Medical Centre, Peter Lougheed Centre, Rockyview General Hospital and, since the autumn of 2013, the new South Health Campus. Last year, over 3000 babies were admitted

to our NICUs. We also provide paediatric inpatient service at the Peter Lougheed Centre (with over 1200 admissions in 2012-13), as well as general paediatric and subspecialty ambulatory clinical services throughout Calgary. We provide palliative and respite care at the Rotary Flames House, located beside ACH. Our physicians travel to provide hundreds of outreach clinics throughout southern Alberta.

The population we serve continues to grow. Last year there were nearly 18,500 births in the Calgary zone. The Government of Alberta estimates that the number of births will continue to increase to nearly 20,000 per year by 2021 and that the number of infants, children and youth aged 19 and under will increase by 20% from 2012 to 2021 (“Alberta Population Projection 2012-2041”). In 2012, there were 356,588 persons aged 19 years and under in the Calgary zone. While we do not have a count of all children cared for by members of the Department of Paediatrics in all facilities and offices across Calgary and southern Alberta, we know that 87,066 children were cared for at the Alberta Children’s Hospital in 2012-13, which represents a 17% increase over the last 4 years. The proportion of admitted children coming from the Calgary zone, other zones in Alberta and outside Alberta was 83%, 14% and 3%, respectively.

We teach health professionals at all levels throughout the University of Calgary, as well as the Southern Alberta

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Department of paeDiatrics | annual report 20134

Institute for Technology (SAIT) and Mount Royal University. There are 12 Royal College of Physicians and Surgeons of Canada Paediatric Residency Training Programs in Calgary (http://medicine.ucalgary.ca/postgrad). In 2012-13, 93 medical residents and fellows were being trained.

Department members initiate or participate in biomedical, clinical, health services and population/public health research. Our main research partner is the ACH Research Institute for Child and Maternal Health (ACHRI, www.ucalgary.ca/research4kids/).

The Alberta Children’s Hospital Foundation provides generous support to services in the hospital and to research (www.childrenshospital.ab.ca).

Funding of faculty in the Department of Paediatrics is complex. Fee-for-service funding remains the main source of funding. The Paediatric Academic Alternate Relationship Plan (Academic ARP, AARP) supports about 100 FTEs. There are separate Clinical ARPs for each of Neonatology and the Paediatric Intensive Care Unit. The Sections of Hospital Paediatrics and Medical Genetics each have an Alternate Payment Plan (APP). Several PhD members of the Department are supported by the ACH Research Institute (ACHRI) and several department members have salary awards from external research agencies.

In 2013, I completed a five year term as Department Head and, after a rigorous internal and external review, have now been re-appointed for a second term. The first term from 2008 to 2013 was marked by considerable increases in the population served, clinical services and teaching provided and research productivity. During this time, we had a large

growth in both clinical and academic faculty, with 92 new members (37% net increase).

This growth occurred during a time of disruptive changes particularly in the health delivery system (dissolution of Calgary Health Region and formation of Alberta Health Services in 2008-09), provincial research institutions (dissolution of Alberta Heritage Foundation for Medical Research and formation of Alberta Innovates-Health Services in 2010) and academic faculty funding systems (elimination of Department-specific AARPs and currently stalled development of a province-wide AARP). There have also been increasing budgetary restrictions with annual reductions in all sources of funding since 2010. Finally, the large growth in the population of children that we serve has put considerable strain on the limited capacity of available hospital and community facilities.

Despite these serious challenges, the Department of Paediatrics has continued its growth and development as a clinical and academic department with numerous established and emerging areas of excellence. As described throughout this annual report our dynamic, expert and committed Department members, working with their colleagues and partners throughout Alberta Health Services, the University of Calgary and beyond, continue to make notable achievements and advances that are improving the care of children and their families. It is a privilege to serve in this Department and I am thankful for the opportunity to continue to provide leadership.

James D. Kellner MD, FRCPC Professor and Head

���

� James D. Kellner MD, FRCPC Professor and Head

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 5

Vision, Mission, Values

the University of calgary's Department of paediatrics and aHs, calgary Zone, provides care at all levels to infants, children and adolescents from calgary and throughout alberta, as well as our extended referral areas in British columbia and saskatchewan. We are defined by our vision, mission and guiding values. these statements define who we are, how we conduct ourselves, and our purpose as a Department and as individuals.

VisionExcellence in Clinical Service, Advocacy & Leadership,

Research & Education (C.A.R.E.)

missionTo promote, maintain and restore health in children by:• Delivering high quality evidence-based clinical care• Training care givers at all levels• Innovation and Dissemination of new knowledge

VaLUes • Compassion • Respect • Integrity • Collaboration • Leadership • Innovation

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Department of paeDiatrics | annual report 20136

• Behavioral Research Unit – Dr. Deb Dewey• Cardiology – Dr. Frank Dicke• Critical Care – Dr. Simon Parsons• Community Paediatrics – Dr. Stephen Wainer

• Child Abuse – Dr. Neil Cooper• Developmental Paediatrics – Dr. JF LeMay

• Adolescent – Dr. April Elliot• Emergency Medicine – Dr. Angelo Mikrogianakis• Endocrinology – Dr. Daniele Pacaud• Gastroenterology – Dr. Steve Martin• Genetics – Dr. Francois Bernier• Hematology – Dr. Michael Leaker• Hospital Paediatrics – Dr. Michelle Bailey• Infectious Diseases – Dr. Susan Kuhn• Neonatology – Co-Chiefs Dr. Albert Akierman and Dr. Anne Tierney• Nephrology – Dr. Julian Midgley • Neurology – Dr. Jong Rho• Oncology/Bone Marrow Transplant – Dr. Doug Strother• Palliative Care – Dr. Marli Robertson• Respirology – Dr. Mark Anselmo

• Sleep Medicine – Dr. Valerie Kirk• Rheumatology – Dr. Susanne Benseler• Research Methods Team – Dr. Gillian Currie

SECTIONS, DIvISIONS, UNITS

DEPARTMENT HEADPAEDIATRICS

DR. JIM KELLNER

DEPARTMENT MANAGERWES SCHREIBER

SAfETy LEADERDR. SHARRON SPICER

DEPUTy HEADEDUCATION

DR. RON ANDERSON

DEPUTy HEADPROfESSIONAL AffAIRS

DR. vAL KIRK

DEPUTy HEADCLINICAL & STRATEGIC AffAIRS

DR. MIKE LEAKER

DEANfACULTy Of MEDICINE

UNIvERSITy Of CALGARy

AARP CONTROLLERMARCO ROMANzIN

PHySICIAN AffAIRS COORDINATORKELLIE MCKEIL

COORDINATOR PHySICIANREMUNERATION AND CONTRACTS

KAREN RUDD

MANAGER Of ADMINISTRATIvE SERvICES

ALANISE fEATHERSTONE

NEONATOLOGy ARP fINANCIAL ANALySTvACANT

BILLING COORDINATORTAMMy BOUCHARD

Department Organization and Leadership

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zONE MEDICAL DIRECTORCALGARy

ALBERTA HEALTH SERvICES

• Undergraduate Medical Education – Dr. Susan Bannister

• Post-Graduate Medical Education• General Paediatrics – Dr. Kathy Tobler• General Paediatrics – Dr. Deb Fruitman • Developmental Paediatrics – Dr. Ben Gibbard• Emergency Medicine – Dr. Izabella Sztukowski• Endocrinology – Dr. Jonathan Dawrant• Gastroenterology – Dr. Leanna McKenzie• Hematology/Bone Marrow Transplant – Dr. MacGregor Steele• Infectious Diseases – Dr. Rupesh Chawla• Medical Genetics – Dr. Mary Ann Thomas• Neonatology/Perinatology – Dr. Majeeda Kamaluddeen• Nephrology – Dr. Lorraine Hamiwka• Neurology – Dr. Michael Esser • Respirology – Dr. Marielena DiBartolo

• Continuing Medical Education – Dr. Julian Midgley

• Paediatrics• FMC – Dr. Chris Lever• PLC – Dr. Kelleigh Klym• RGH – Dr. Darryl Palmer• SHC – Dr. Harish Amin

• Neonatology • ACH – Dr. Alixe Howlett• FMC – Dr. Anne Tierney• PLC – Dr. Essa El Awad• RGH – Dr. Deborah Clark• SHC – Dr. Harish Amin

UME, PGME, CME PROGRAMS AND DIRECTORS SITE CHIEfS

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Department of paeDiatrics | annual report 20138

Description of Department Members

Within the 18 Clinical Sections, 3 Clinical Divisions and 3 Academic Units, there were 285 members as of September 2013. Of these, 242 had primary academic appointments to Paediatrics and 43 had cross-appointments. This slightly reduced number from 2012 reflects a more precise count and the interim status of several new members. Most members are MDs (or equivalent), while 25 members are PhDs.

The median age in the Department is 46 years and the range is 29 to 81 years. The female/male ratio in the Department is now approximately 50%/50%. Amongst members less than 50 years old, 65% are female, while amongst members 50 years or older, 35% are female.

The largest 4 sections, comprising 56% of all members, include:

• Community Paediatrics (55 members)

• Emergency Medicine (52 members)

• Hospital Pediatrics (30 members)

• Neonatology (24 members)

The other sections, divisions and units have 3 to 15 members.

Members of the Clinical Section of Genetics are also primary Academic members of the Faculty of Medicine Department of Medical Genetics. Members of the Clinical Section of Oncology are also primary Academic members of the Faculty of Medicine Department of Oncology.

ACADEMIC STATUS

Status Primary appointments (242)  Cross appointments (51)

  Clinical Faculty

adjunct/research Faculty

gFT Faculty

Clinical Faculty

adjunct/research Faculty

gFT Faculty

Lecturer 15 2  0 0   0  0

Assistant Professor 107 8 22 6 2 10

Associate Professor 35 4 26 4 0  10

Full 4 3 16 2 1 8

Totals 161 17 64 12 3 28

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 9

Zone Paediatric Executive Committee 2013

� FRONT ROW, SEATED: Drs. Susan Kuhn (Infectious Diseases), Sharron Spicer (Safety), Marli Robertson (Palliative Care), Val Kirk (Deputy Head, Professional Affairs), Jim Kellner (Department Head), April Elliott (Adolescent Medicine), Frank Dicke (Cardiology)

MIDDLE ROW: Drs. Bill Hyndman (Surgery, guest), Angelo Mikrogianakis (Emergency), Jong Rho (Neurology), Deb Dewey (Behavioural Research Unit), Deb Fruitman (General Paediatrics PGME Program), Albert Akierman (Neonatology), Abdul Rahman (Child Psychiatry, guest), David Chaulk (Facility Medical Director, guest), Daniele Pacaud (Endocrinology), Gillian Currie (Research Methods Team), Julian Midgely (Nephrology and Continuing Medical Education), Jean-Francois Lemay (Developmental Paediatrics)

BACK ROW: Mr. Wes Schreiber (Department Manager), Drs. Stephen Wainer (Community Paediatrics), Simon Parsons (Critical Care), Michelle Bailey (Hospital Paediatrics), Susa Benseler (Rheumatology), Mike Leaker (Deputy Head, Clinical and Strategic Affairs, and Hematology), Steven Martin (Gastroenterology), Mark Anselmo (Respirology), Ron Anderson (Deputy Head, Education), Susan Bannister (Undergraduate Medical Eduction), Doug Strother (Oncology)

MISSING: Ms. Margaret Fullerton (ACH VP, guest), Drs. Harish Amin (Site Leader, South Health Campus), Francois Bernier (Medical Genetics, Jeremy Luntley (Anaesthesia, guest).

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Department of paeDiatrics | annual report 201310

Administrative, Support and Research Staff

DEPARTMENT ADMINISTRATIVE OFFICES

WES SCHREIBER - Department Manager

ALANISE FEATHERSTONE - Office Manager

MARCO ROMANZIN - AARP Controller

KAREN RUDD - Physician Contracts and Remuneration Coordinator

KELLIE MCKEIL – Physician Affairs Coordinator

TRACEy BOyLE - Administrative Assistant

KAREN CROUCHER - Administrative Assistant (Drs. Kellner and Leaker)

CLAIRE TROjAN - Administrative Assistant (Drs. Anderson and Kirk)

SHAHIN HASSAM – Administrative Assistant

KARI SPENCER – Administrative Assistant

TAMMy BOUCHARD - Billing Coordinator

KELLy CRAIG - Billing Clerk

PATRICIA ROyLE - Billing Clerk

NICK HEAZELL – Website and Design Admin

There are over 75 administrative assistants, other support and research staff who support the department at all Alberta Health Services and University of Calagary sites.

���

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Overview of Clinical Sections and Divisions, and Research Units

sections & DiVisions

Adolescent Medicine

Cardiology

Community Peadiatrics

Critical Care

Developmental Peadiatrics

Emergency Medicine

Endocrinology

Gastroenterology

Hematology

Hospital Pediatrics

Infectious Diseases

Medical Genetics

Neonatology

Nephrology

Neurology

Oncology

Palliative Medicine

Respiratory

Rheumatology

ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 13

researcH Units

Behavioural Research Unit

Research Methods Team

Maternal and Child Team: Dr. Suzanne Tough

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Department of paeDiatrics | annual report 201314

HIGHLIGHTS

In 2012 Community Outreach of Pediatrics and Psychiatry in Education (COPE) expanded to include junior and high school youth, continuing with the same underlying principles that marked the success of the original COPE service: school based identification of youth struggling with medical or emotional issues impacting success at school, comprehensive pediatric or psychiatric consultation, medical treatment, case management by COPE family liaisons, family therapy as appropriate by the COPE therapist, and referral to appropriate resources.

Ms R. Wadman (CNS) and Dr Pinzon, adolescent medicine specialist, joined the COPE physician team in the 2012-2013 school year to provide services to the referred adolescents. The youth presented with multiple complex issues including learning difficulties, mental health issues, drug use, family system problems, social issues, and behaviour problems. Through COPE 43 youth received physician consultation in a variety of schools in Calgary and area. Due to the complex nature of their issues, many youth needed to be seen on multiple occasions.

youth, families, and school personnel have reported successes as a result of the adolescent COPE initiative, for example, medication management of mental health concerns, improved school attendance, referrals for counselling, and increased motivation to engage with school.

PHySICIaN/FaCulTy lISTINg:

Dr. April Elliott – Division Chief

Dr. Jorge Pinzon

Dr. Ellie Vyver

Photo courtesy of Bill Longstaff via Flickr’s Creative Commons-licensed content

Section of adolescent medicine

One of the challenges that both families and youth face is that they are not connected to family physicians. This is one of the critical roles that schools play; they are able to connect families to physicians through their partnership with COPE. One role of the family liaisons is to then help the family to access a family physician.

COPE is a partnership between Alberta Health Services, school jurisdictions in Calgary and area, and Child and Family Services. COPE is a true example of an interasectoral collaboration that benefits youth and their families across the multiple systems they are in contact with. ���

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ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 15

every year over 6000 children present to the alberta Children’s Hospital emergency department because of vomiting or diarrhea (usually referred to as gastroenteritis). Typical treatment involves ensuring the children maintain adequate hydration; however, physicians have little to off er to help symptoms resolve sooner. Times are changing - a team of researchers, led by Dr. Freedman, from the Alberta Children’s Hospital Emergency Department, are conducting a national study (PROGUT – Probiotic Regimen for Outpatient Gastroenteritis Utility of Treatment) evaluating the use of a novel therapy – probiotics – in children with diarrhea and vomiting. With funding provided by the Canadian Institutes of Health Research, nearly 900 children will be enrolled over the next 3 years in 5 Canadian Paediatric emergency departments to determine if probiotics should be used to help aff ected children feel better sooner.

Interest in this work is not limited to Canada; the National Institutes of Health in the United States is funding a similar probiotic study (using a diff erent product), which is being co-led by Dr. Freedman and will include 8 Paediatric emergency departments. The latter study is being conducted concurrently and will also include nearly 900 children.

PROGUT(Probiotic Regimen for Outpatient Gastroenteritis Utility of Treatment)

Together these landmark studies will clarify the role of probiotics in children with gastroenteritis. These endeavours build on Dr. Freedman’s prior innovations in the fi eld of gastroenteritis which includes the introduction into routine use of a medication which helps expedite the resolution of vomiting and the development of a severity of disease score which is being used as a standardized outcome in gastroenteritis research. Additionally, his research program has expanded to include developing countries such as Pakistan, where he is now evaluating the use of anti-vomiting medications with funding provided by the Bill & Melinda Gates Foundation and the Thrasher Research Fund. ���

s p e c i a l f e a t u r e

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DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201316

Paediatric Update Conference

The inaugural aCH Paediatric update Conference took place in the Kinsmen learning Centre of the alberta Children's Hospital on the 10th and 11th of May 2013.

The main objective of the conference was to gain new knowledge to improve management of patients and optimise referrals to tertiary care. The conference attracted over 100 physicians and health care workers from Alberta, British Columbia and Saskatchewan who had a mix of plenary and breakout sessions on a wide variety of medical and surgical topics relevant to presented by faculty from the Alberta Children's Hospital.

The key note speaker was Dr Harriet MacMillan from the Offord Centre for Child Studies at McMaster University who gave a stimulating address on "Responding to Child Maltreatment: Lessons Learned and Where from Here?" The conference ended with a lively and interactive Provocative Panel that debated “Is childhood obesity a social problem or a medical problem?”. A post conference Simulation Course took place with a hands on experience for "Paediatric Acute Care in the Office: The first few minutes". The conference received excellent evaluations from the attendees and a second Paediatric Update Conference is planned for 2014.

Further details on the Conference can be seen by visiting this URL: http://medicine.ucalgary.ca/files/med/FINAL_ACHPaedUpdate_13.pdf ���

s p e c i a l f e a t u r e

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 17

HIGHLIGHTS

Our latest staff additions include:

�Dr. steven Greenway - Sept 2012 - expertise in heart failure, heart transplant and cardiac genomics

�Dr. erika Vorhies - Sept 2013 - expertise in pulmonary hypertension and cardiac critical care

The section of Cardiology continues with its excellence in cardiac imaging including cardiac MRI, CT, and echocardiography performance, teaching, and research, driven by Drs. patton and myers.

Over the past year we have also instituted a home defibrillator program for at risk arrhythmia patients spearheaded by Dr. robin clegg.

Dr. Joyce Harder in association with Dr. Pam Veale have initiated a developmental screening protocol in clinic.

Dr. Greenway has initiated a home and ward milrinone protocol to keep patients out of the ICU.

Dr. Giuffre has served as AMA president and Dr. Fruitman has been fully active as paediatric program director while continuing her expertise in fetal echocardiography.

Section of cardiology

Drs. Dicke and myers are also involved with global health and the initiation of projects to help improve paediatric cardiac care in Georgetown Guyana in association with the Libin Cardiovascular Institute. ���

Dr. Robin Clegg and Clinic Nurse Patty Knox of the Home Defibrillator Program with their home defibrillator.

PHySICIaN/FaCulTy lISTINg:

Dr. Frank Dicke - Section Chief

Dr. Robin Clegg

Dr. Deb Fruitman

Dr. Michael Giuffre

Dr. Steven Greenway

Dr. Joyce Harder

Dr. Kim Myers

Dr. David Patton

Dr. Erika Vorhies

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Department of paeDiatrics | annual report 201318

Section of community paediatrics

HIGHLIGHTS

The Section of Community Paediatrics (SCP) continues to focus on enhancing the quality of medical care being provided in the community. This is being achieved through programs that improve communication and collaboration with primary care providers, enable easier access to community paediatric consultation services, promote and support shared-care models for complex patients and address the lack of resources that community paediatricians face in office practice. Examples of these initiatives include:

�paedlink telephone consultation service: provides family physicians with easy and immediate access to telephone consultations from community paediatricians. This service enhances paediatric care in the community, reduces the need for emergency room visits and specialist referral, and promotes collegiality and communication between community paediatricians and family physicians.

�community paediatric resource Website (calgarypaeds.org): the myriad and ever-changing landscape of community agencies, websites and other resources is a constant challenge for paediatricians and families and this growing website focuses on providing up to date and relevant information for a very wide range of conditions and services.

�primary care network (pcn) affiliations: in order to provide a greater range of services a number of clinics have joined PCNs. These novel partnerships have facilitated dietitian, resource navigation and other resources and have greatly improved the ability of community paediatricians to provide comprehensive and quality care.

� Dr. Kristin Evashuk from the Paedlink Telephone Consultation Service.

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 19

PHySICIaN/FaCulTy lISTINg:

Dr. Stephen Wainer - Section Chief

Dr. Kelleigh Klym - PLC Site Chief

Dr. Christopher Lever - FMC Site Chief

Dr. Darrell Palmer - RGH Site Chief

Dr. Jennifer Macpherson - Medical Lead, Child Abuse Program

Dr. Susan Aitken

Dr. Hilda Angeles

Dr. Rachel Bond

Dr. Starr Cardwell

Dr. Nathaniel Chan

Dr. Neil Cooper

Dr. Kate Culman

Dr. Alfred Dei-Baning

Dr. Amanda Evans

Dr. Kristin Evashuk

Dr. Natalie Forbes

Dr. Frank Friesen

Dr. Cara Gilman

Dr. Roxanne Goldade

Dr. Sivalingum Govender

Dr. Janice Heard

Dr. Hardally Hegde

Dr. Della Ho

Dr. Keith Jorgenson

Dr. Michele Kalny

Dr. Cham-Pion Kao

Dr. Lori Kardal

Dr. Suba Karthikeyan

Dr. Brian Kelly

Dr. Victoria Kendrick

Dr. Alexander Leung

Dr. Linda Loovere

Dr. Roderick Mackenzie

Dr. Kathleen Mitchell

Dr. Danielle Nelson

Dr. Jane Ng

Dr. Peter Nieman

Dr. Steven Olliver

Dr. Lane Racher

Dr. Swait Rastogi

Dr. Swoti Rastogi

Dr. Lauren Redgate

Dr. Lioba Redel

Dr. Novak Michele

Dr. Daniel Ross

Dr. Heidemarie Schroter

Dr. Elizabeth Shyleyko

Dr. Cheri Stanzeleit

Dr. Pamela Stone

Dr. Tracy Taylor

Dr. Byron Wong

Dr. Monique Wright

Dr. John Wu

Dr. Douglas Yeung

Dr. Desiree Yow

�central consultation service: will allow “one-stop” access to community paediatrician consultation. This service will ensure that family physicians, in-patient units, emergency rooms and other referring agencies are able to obtain the “first available” paediatrician appointment at a clinic convenient to the parent. It is anticipated that this will substantially reduce the frustration and complexity of connecting a child with a paediatrician, greater parent satisfaction and timelier access to specialist medical care.

�neurology shared-care project: a collaboration with the Section of Paediatric Neurology to support community paediatric care of children with seizures and other neurologic concerns. This project aims to ensure greater communication and collaboration between neurologists and community paediatricians. An immediate goal is the development of share-care models for epilepsy management.

This year Dr. Starr Cardwell, Dr. Kathleen Mitchell, Dr. Cheri Stanzeleit and Dr. Vicki Kendrick retired from clinical practice. These physicians have provided exemplary service over many years in practice and their commitment, advocacy, expertise and service to Community Paediatrics will be sorely missed. We wish them all the best for the future. ���

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Department of paeDiatrics | annual report 201320

HIGHLIGHTS

The Paediatric Intensive Care Extra Corporeal Life Support (ECLS) Program

What is ECLS?

ECLS is a temporary lung and/or heart support system which can be used on newborns, children and adults. This treatment is used in our Paediatric Intensive Care Unit for children with acute life-threatening reversible respiratory or cardiac failure who are not responding to maximal ventilator, medical and surgical treatment. Our new ECLS program provides these infants and children another chance at survival.

Why we are unique?

Unlike other paediatric hospitals with ECLS programs, the Alberta Children’s hospital does not have a Paediatric Cardiac Surgery program. There are no cardiac surgeons or perfusionists located in our hospital to provide support in the initiation of ECLS therapy and/or care after therapy is started. In addition, we currently do not have 24 hour access to in-house general surgeons to respond to emergency issues related to ECLS therapy.

How did this impact our new program?

In order to launch this important new treatment program

Section of critical care

� Logan Borthwick

was the first ECLS cannulation patient.

Logan is now happy and healty.

PHySICIaN/FaCulTy lISTINg:

Dr. Simon Parsons – Section Chief

Dr. Kathleen Tobler – General Paediatric PGME Program Director

Dr. Jaime Blackwood

Dr. Shauna Burkholder

Dr. Robin Cox

Dr. Tanya Drews

Dr. Jonathan Gamble

Dr. Elyahu Gilad

Dr. Elaine Gilfoyle

Dr. Jeremy Luntley

Dr. Meagan Mahoney

Dr. Barbara Catherine Ross

Dr. Terry Stewart

for our critically ill population, we had to train all our team members for a brand new program.

Starting the Program

Our extensive training process included the General Surgeons, Cardiologists, OR nurses, Paediatric Intensivists, Nurses and Respiratory Therapists. In addition we needed to train a perfusionist and an ECLS specialist. Thanks to support from the Alberta Children’s Hospital Foundation, we were also able to secure the specialized equipment needed for the ECLS program.

How many children have needed ECLS?

The ECLS team has been activated for potential initiation of therapy a total of 39 times to date. In 18 of these cases, ECLS has been initiated with an overall survival rate of 83%

• 14 of these children are currently healthy and back in their homes

How are we doing compared with other centers?

• The Extra Corporeal Life Support Organization (ELSO) has a database that tracks children put on ECLS internationally.

• The survival rate for children to be discharged home who have received ECLS is between 41% and 57% according to ELSO.

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 21

• ACH has a current survival rate for children to be discharged home of 83% with full neurological recovery in all by one.

• It is certainly our belief that all fifteen survivors would have died without ECLS.

• In some cases (4) the heart had actually stopped beating effectively or completely – half of children in this group survived.

• Most children we have treated with ECLS at the Alberta Children’s Hospital had serious infections including septic shock.

• Most ECLS centers do not treat septic shock with ECLS, believing it will not be successful.

• Death from infection remains one of the most significant challenges of Intensive Care Medicine today but our ACH PICU mortality rate for severe infections (non-neurological) is now approaching zero.

We Are Very Proud of

• The efforts of our community that helped to fund this program.

• Our hard work to implement the program.

• A success rate that is second to none.

• A reduction in our overall PICU mortality by 20-30%

• We are saving the lives of an additional 6-10 children per year. ���

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Department of paeDiatrics | annual report 201322

HIGHLIGHTS

The Developmental Paediatric Section is a group of developmental pediatricians, child psychiatrists and child neurologist. We are a service of excellence for Neurodevelopmental Disorders. Our section members offer expertise in Autism, ADHD, developmental disabilities, paediatric rehabilitation, child psychiatry and abuse, and paediatric neurology.

The section of Developmental Paediatrics and the ACH/Child Development Service, located at the Child Development Centre, is working closely in an ongoing significant service model with changes to meet the growing demand, change in demographics and complexity of the paediatric population we serve.

Two key areas under development include:

• Emphasis on the early recognition of social risk factors associated with complex neurobehavioral disorders that contribute to secondary and tertiary prevention initiatives.

• Development of an effective testing modality for Autism Spectrum Disorder which would support Level I screening in partnership with community providers and referral of the more ‘difficult to diagnose’ children to our tertiary service.

Section of Developmental paediatrics

Innovative Project Highlights

Following two major donations made to Alberta Children’s Hospital Foundation, 2 members of our section are significantly involved in the following:

• Dr. ted prince is the Interim Medical Lead for Rehabilitation in the Vi Riddell Pain and Rehabilitation Center (work in collaboration with the ACH Foundation and AHS). The goals of this rehabilitation program include:

1. Expanding assessment services to develop meaningful, motivating goals with families and the rehabilitative team.

2. Creating additional programming that fosters independence and meaningful participation by disabled children and youth.

3. Fostering a support network for disabled children and youth, and their families.

4. Expanding opportunities for care providers to develop advanced skills related to pediatric rehabilitation.

• Dr. Jean-françois Lemay was the Chair of the Brain Health, Neurodevelopmental Disorders Working Group who worked on the vision and roadmap of the future

PHySICIaN/FaCulTy lISTINg:

Dr. Dr. Jean-François Lemay – Section Chief

Dr. Ben Gibbard – PGME Program Director

Dr. Jennifer Fisher

Dr. John McLennan

Dr. Alison Moore

Dr. Ted Prince

Dr. Heidi Schroter

Dr. Pamela Veale

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 23

� Dr. Jean-Francois Lemay at the Child Development Centre

Alberta Children’s Hospital Centre of Excellence in Neurodevelopmental Disorders (work in collaboration with the ACH Foundation and AHS).

Clinical Services Provided

• Ambulatory Clinics and Services offered at the ACH/Child Development Services include:

a. Developmental Paediatric Clinics

b. Developmental Psychiatry Clinics

c. Consultative Clinics (Phone) for Community Pediatricians

d. Developmental Neurology Clinics

e. Child Development Medication Assessment Services

f. Fetal Alcohol Spectrum Disorder Clinics

• Our section does not offer 24/7 Inpatient or Admitting Services. However, we are offering on-call and emergency outpatient consultation services if required and consultation to Child Abuse Services is provided when needed. ���

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DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201324

HIGHLIGHTS – CLINICAL CARE, EDUCATION AND RESEARCH

Delivering high quality evidence-based clinical care

• Annual census of 72,000 ED visits (increase of 10% over previous year)

• 85% of all paediatric ED visits in Calgary are seen at ACH• Highest percent of ED patients discharged within 4

hours (Calgary Zone target time interval)• Continuous innovation in patient care strategies for

effi cient clinical fl ow• january 2013 began 12 hr/day PEM coverage at the

South Health Campus• Leaders in regional/provincial/national clinical care

pathway development• Asthma, Gastroenteritis, Appendicitis, Status

Epilepticus, Sepsis• New initiatives in quality improvement and patient safety

Training caregivers at all levels

• Paediatric Emergency Medicine Training Program (2012/13):

• PEM Residency: 7 PEM subspecialty trainees• 186 Mandatory rotations for residents from

other programs

Section of emergency medicine

• 67 Clinical Clerks UofC• 54 Visiting Learners• 81 fi rst year Family Medicine Residents at the SHC• 4 Nurse Practitioner trainees

• PEACH - Hosted 2nd Paediatric Emergency Medicine CME Conference

• 120 community physicians and nurses attended from across Alberta, western Canada and internationally

• PALS (Paediatric Advanced Life Support) Training and certifi cation courses

• Paediatric Resident Quality Improvement Curriculum• Paediatric Simulation

• Interprofessional team training with allied health professionals (RN and RRT) and all levels of medical trainees (UME, PGME, Fellowship, Attending Physicians)

• Simulation leaders at ACH, U of C, provincially, nationally and internationally

• Mobile (Outreach) Simulation educating around acute care paediatrics to community partners in their local settings across Southern Alberta and Southeastern British Columbia

• 20-24 rural and regional centres per year

• Over 500 health care professionals per year

85%

of all paediatric eD visits in calgary are seen at the alberta children’s hospital

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 25

PHySICIaN/FaCulTy lISTINg:

Dr. Angelo Mikrogianakis – Section Chief

Dr. Kelly Millar – PGME Program Director

Dr. Graham Thompson – Acting PGME Program Director

Dr. Ed Les – ACH Clinical Lead (to Sept 2012)

Dr. Mary-Louise O’Byrne – ACH Clinical Lead (from Sept 2012)

Dr. Francois Belanger

Dr. Donald Bethune

Dr. Michele Bjornson

Dr. Andrea Boone

Dr. Mark Bromley

Dr. Gavin Burgess

Dr. David Chaulk

Dr. Adam Cheng

Dr. Seen Chung

Dr. Shawn Dowling

Dr. Jenn D’Mello

Dr. Marc Francis

Dr. Stephen Freedman

Dr. Roger Galbraith

Dr. Jennifer Graham

Dr. Jeffrey Grant

Dr. Vince Grant

Dr. Jonathan Guilfoyle

Dr. Carey Johnson

Dr. David Johnson

Dr. Kevin Johnson

Dr. Kristen Johnson

Dr. Christine Kennedy

Dr. Tanuja Kodeeswaran

Dr. Verna Krisik

Dr. Russell Lam

Dr. Kerri Landry

Dr. Lorraine Mabon

Dr. Gordon Mcneil

Dr. Andre Michalchuk

Dr. Sarah McPherson

Dr. Patrick Milhalicz

Dr. Cheri Nijssen-Jordan

Dr. Lisa Odendal

Dr. Adam Oster

Dr. Naminder Sandhu

Dr. Katharine Smart

Dr. Derrick Smith

Dr. Antonia Stang

Dr. Izabela Sztukowski

Dr. Margaret Thomson

Dr. Jennifer Thull-Freedman

Dr. Hussein Unwala

Dr. Philip Ukrainetz

Dr. Ping Wei Chen

Dr. Ian Wishart

Dr. Bryan Young

Innovation, Research and Dissemination of new knowledge

ACH clinician scientists and educators are national and international leaders at:

1. Generating best evidence for the care of severely ill and injured children,

• PROGUT: Probiotic Regimen for Outpatient Gastroenteritis Utility of Treatment study

• Concussion

2. Determining the best ways to teach health care professionals to incorporate new knowledge into their practice,

• National Centre of Excellence - Knowledge Mobilization: TRanslating Emergency Knowledge for Kids (TREKK)

3. Developing collaborative educational and research programs using Simulation:

• Providing clinicians the skills and confidence to care for sick children

• Assessing and improving the quality of CardioPulmonary Resuscitation (CPR)

• Examining Paediatric Resuscitation Education using Simulation and Scripted Debriefing (EXPRESS)

• International Network for Simulation-based Innovation, Research and Education (INSPIRE network)

• Trauma Resuscitation in Kids (TRIK) national trauma course

4. Developing clinical indicators for determining if severely ill and injured children receive optimal care.

• The Development of Quality Indicators for High Acuity Paediatric Conditions Requiring Emergency Care. ���

4hourshighest percent of eD patients DischargeD within (Calgary Zone target time interval)

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Paediatric Emergency Medicine at the South Health Campus

On January 13, 2013 the pediatric emergency physicians of the alberta Children’s Hospital (aCH) embarked on a new initiative to better serve the children and families of Calgary and the surrounding area.

Pediatric Emergency Medicine physicians would provide twelve hours of pediatric coverage per day at the new South Health Campus Emergency Department. This model of a satellite Pediatric Emergency Department was a first in Calgary, as well as in all of Canada. It made sense for the following reasons:

• TheAlbertaChildren’sHospitalwasverybusyseeingover200 patients per day, for a total of 72,000 visits per year;

• Manyyoungfamiliesliveinthesoutheast;

• Calgary’sgrowthwouldjustifytwositesforfamiliestoreceive high level pediatric emergency care.

The South Health Campus Emergency Department provides options and convenience for families and their children. Approximately 1,200 pediatric patients are cared for at the South Health Campus Emergency Department each month. Both the South Health Campus Emergency Department and the Alberta Children’s Hospital Pediatric Emergency Medicine physicians should be commended for this new partnership that benefits the children and families of Calgary by ensuring high-level pediatric care across the city. ���

DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201326

s p e c i a l f e a t u r e

� Dr. Cheri Nijssen-Jordan in action with a family at the SHC Paediatric Emergency Department

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Department of paeDiatrics | annual report 201328

HIGHLIGHTS

For the Section of Paediatric Endocrinology, this past year has been mark by the launch of two new programs: 1) Implementation of the Provincial Insulin Pump Therapy Program at the ACH diabetes clinic and 2) the Paediatric centre for Weight and Health: Calgary Site.

Implementation of the Provincial Insulin Pump Therapy Program at the ACH Diabetes clinic:

Management of type 1 diabetes involves subcutaneous delivery of insulin either through multiple daily injections or through a continuous insulin infusion pump. Use of a pump requires special knowledge and significant extra costs to the families choosing this mode of treatment. However, it is the most physiologic way to deliver insulin providing better diabetes control and more flexibility with daily routines.

In june of 2013, the Provincial Insulin Pump Program was launched. Our clinic has been a key player in setting up the eligibility criteria and standard of care for the paediatric part of this program. Further, our clinic has continued to provide education and support for those already using this therapy and for those wishing to start using it. Currently in our clinic, ~60 children are switch to this therapy each year and about 20% of children affected by type 1 diabetes are managed with an insulin pump.

Section of endocrinology

Visit the webpage to keep up to date on services and hours: http://ow.ly/rcijY

The new Provincial Program has significantly lessened the financial burden of this form of therapy for individuals with type 1 diabetes as illustrated by this mother’s testimony:

“The insulin pump significantly improved our quality of life by giving back to us some sense of normalcy and it also gave us the ability to achieve significantly better glycemic control. We paid out-of-pocket for 10 years to continue using it. We calculated that by the time the insulin pump program came into effect, that we had sacrificed close to $85,000 on three insulin pumps and all the monthly supplies.Having the Alberta Pump Program provide coverage for insulin pumps and supplies was a very positive turning point in our lives. We could now use this amazing medical device that had been responsible for increasing our quality of life and achieving excellent glycemic control without having to make huge financial sacrifices in return.”

The Paediatric Centre for Weight and Health: Calgary Site

Childhood obesity is major health concern since it is increasing in prevalence and has significant associated co-morbidities which can have a large impact on quality of life and future health. The goal of the Alberta Health Services pediatric provincial weight management initiative was

PHySICIaN/FaCulTy lISTINg:

Dr. Danièle Pacaud - Section Chief

Dr. Jonathan Dawrant - PGME Program Director

Dr. Paola Luca

Dr. Josephine Ho

Dr. Carol Huang

Dr. Rebecca Perry

Dr. David Stephure

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 29

to develop a coordinated and comprehensive approach to preventing and managing childhood obesity and an expansion of services for children and families in order to reduce the burden of disease in Alberta. As a part of this, a specialty care clinic for pediatric obesity was started at the Alberta Children’s Hospital (ACH) and has been operating fully for approximately one year.

The ACH specialty clinic is comprised of paediatric endocrinologists, pediatricians, registered dietitians, nurses, exercise physiologist, social worker and psychologist. The goal of this clinic is to help overweight and obese children and their families by focusing on achieving healthy lifestyle changes. The first clinicians at PCWH started in May 2012 with a few patients seen and the clinic was officially launched in October 2012. Currently, there are approximately 138 active patients in the clinic and we will be expanding services to include the South Health Campus with clinics starting November 27, 2013. In addition, we hope to continue expanding services to include group teaching sessions such as healthy cooking classes in the near future.

Visit the webpage to keep up to date on services and hours: http://ow.ly/rcGt6 ���

� From Left to right: Dr. Rebecca Perry, Dr. Paola Luca, Dr. Jonathan Dawrant, Dr. Danièle Pacaud, Dr. Josephine Ho, Dr. Carol Huang

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Department of paeDiatrics | annual report 201330

HIGHLIGHTS

Alberta Children’s Hospital re-establishes a state-of-the- art gastrointestinal motility laboratory.

The recruitment of Dr Alfred yeung to the section of Gastroenterology, Hepatology and Nutrition has re-established Alberta Children’s Hospital as a national leader in the evaluation and management of children with gastrointestinal motility disorders.

With the generous support of the Alberta Children’s Hospital Foundation, the purchase of technologically advanced manometry and pH/MII equipment now enables us to provide specialty GI motility services including high resolution esophageal and ano-rectal manometry, water-perfused small intestinal and colonic manometry, and comprehensive motility testing for children.

Dr yeung completed a sub-specialty fellowship in Paediatric Gastrointestinal Motility at Nationwide Children’s Hospital in Columbus Ohio and together with his team has been working hard since his arrival in August of 2012 to establish the operating procedures for the Motility Laboratory. With the recent approval to begin operations, ACH will evolve into the paediatric GI motility referral centre for Western Canada as this expertise is currently available in only two centres in Canada and in only a dozen centres across the United States. ���

Section of Gastroenterology

PHySICIaN/FaCulTy lISTINg:

Dr. Steven Martin – Section Chief

Dr. Dana Boctor

Dr. J. Decker Butzner

Dr. Jennifer deBruyn

Dr. Helen Machida

Dr. Leanna McKenzie – Program Director

Dr. Brent Scott

Dr. Chris Waterhouse

Dr. Iwona Wrobel

Dr. Alfred Yeung

� Pictured are Dr. Alfred Yeung, along with Kristine Thannhauser and Doreen Reid.

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 31

HIGHLIGHTS

The Section of Hematology provides care for children with a wide variety of diseases of the blood and bone marrow, bleeding and thrombotic disorders and immune deficiency syndromes, both congenital and acquired.

A new initiative for the Section over the past year has been the establishment of a formal, multidisciplinary clinic for children with hemoglobinopathies such as sickle cell disease and various thalassemia syndromes. Migration into our referral area over the past several years has resulted in a rapid expansion of this population from approximately 20 in 2009 to more than 80 in 2013.

Section of Hematology

PHySICIaN/FaCulTy lISTINg:

Dr. Doan Le

Dr. Michael Leaker - Section Chief, Deputy Department Head

Dr. MacGregor Steele – Hermatology and Oncology PGME Program Director

Dr. Nicola Wright

These patients learn to manage a lifelong condition and many will develop multisystem involvement during their years in the pediatric clinic. By focusing on providing multiple services in a single visit, we hope to optimize the care for these patients and decrease the number of visits their families must make. At present, as part of each clinic visit, we are able to offer assessment and treatment by:

• Specialized primary nursing• Advanced practice nursing• Dietician• Neuropsychology• Specialized diagnostic services (eg, transcranial

Doppler, pulmonary function testing)• Social work• Hematologist• Respirology

In an ongoing effort to reduce the burden of care for these families, we are working to add additional services such as a dedicated pain management physician to our team. We also hope to increase the resources available to our patients through the creation of a patient and family support group. This clinic is an example of how social factors such as migration can, in a very short timeframe, move a group of disorders from relatively rare to a major focus for our Section. ���

establishment of the formal multiDisciplinary hemoglobinopathies clinic

Migration into our referral area has resulted in a rapid

expansion of this population from approximately

20 IN 2009

80+ IN 2013

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Department of paeDiatrics | annual report 201332

Section of Hospital paediatrics

HIGHLIGHTS

Simulation Education Programs: The Human Patient Simulation (HPS) Program

Paediatricians in the Section of Hospital Paediatrics (SHP) at the Alberta Children’s Hospital have a unique responsibility to provide acute and complex care to 85% of the medical in-patients as well as provide leadership to the ACH “Code Blue” team (responding to a patient experiencing a respiratory or cardiac arrest) on a 24/7 basis. In response to the need to maintain, practice and acquire new knowledge and skills needed to provide these front-line medical in-patient services, a professional development initiative called the Human Patient Simulation (HPS) program was created and launched in 2005.

HPS sessions are 3.5 hours in duration and sessions are conducted twice per month. Each hospital pediatrician participates in 2 half-day sessions per year. Sessions are multi-disciplinary in nature and include hospital paediatricians, unit nurses, respiratory therapists and the STEP team. Each session consists of an orientation followed by three in-patient case scenarios with dedicated time for debriefing. The HPS curriculum for any given year is based on an annual “needs assessment”

conducted by collecting feedback from all participating multi-disciplinary groups and consultation with clinical leaders in the Section. Scenarios are designed to simulate the types of patients (both acute and complex) and common urgent/emergent situations (i;e: respiratory distress or arrest, sepsis, anaphylaxis, seizure, etc) that may be typically experienced on the in-patient units. Specific curricular emphasis is placed on code team roles, quality improvement initiatives, patient safety issues, technical skills, introduction and practice of “institution specific” clinical care guidelines and protocols, orientation to new medical equipment, response to communication challenges (including disclosure of adverse events) and inter-disciplinary team building.

The HPS program was created and is directed by Dr. Suzette Cooke. HPS session leaders, Drs. Sarah Hall, Lindsay Long and Suzette Cooke are all certified simulation instructors. Nursing educators from Units 2, 3 and 4 co-lead these sessions and support debriefing of the nursing staff.

The HPS program at ACH is the only known multi-disciplinary staff pediatric simulation continuing professional development program in North America. The HPS program is one of the many unique and innovative programs found under the ACH KidSim umbrella!

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 33

PHySICIaN/FaCulTy lISTINg:

FULL AARP POSITIONS

Dr. Michelle Bailey (Section Chief)

Dr. Suzette Cooke (Section HPS Lead, U of C Faculty Education)

Dr. Gemma Vomiero (Deputy Section Chief)

Dr. Susan Bannister (Clerkship Lead for Paediatrics)

Dr. Preet Sandhu (Section Clerkship Lead/ Educational Research)

Dr. Chantelle Barnard (Family Centered Care/ Clinical Lead/Research)

PARTIAL AARP POSITIONS

Dr. Julie Fisher (Complex Care Lead)

Dr. Sarah Hall (Section Resident Lead/ Staff Education)

Dr. Aaliya Sabir (Quality Improvement)

Dr. Hani Hadi (IT and Informatics/ Scheduling)

Dr. Jenn Brenner (International Health)

CLINICAL/EDUCATION POSITIONS

Dr. Lindsay Long (JIT lead)

Dr. Gary Chow

Dr. Laura Davies

Dr. Dominique Eustace

Dr. Barbara Grueger

Dr. Renee Jackson

Dr. Quyen Lam

Dr. Lisa Lemieux

Dr. Catherine Macneil

Dr. Cristina Stoian

Dr. Sidd Thakore (Followup Clinic Lead)

Dr. Mike Vila

Dr. Chris Andrews

Dr. Michelle Jackman

Dr. Lori Walker

Dr. Theresa Wu

Dr. Mary Fras (locum)

PART TIME

Dr. Melissa Gross

Dr. Kevin Levere

Here are some examples of what our participants have to say about HPS:

“Real – life scenario’s practiced in a safe learning environment” RN

“I love that these sessions are multi-disciplinary – this helps make it real!” R.T/ STEP Team

“The scenarios were very representative of what we see on our unit. Practicing both the medicine and the teamwork and communication was awesome! Learned a lot in the debriefing too!” - RN

“Excellent hands-on experience! This helps me maintain my readiness for the real thing.” M.D

The “just in Time” (jIT) Program

just In Time (jIT) training is a high fidelity simulation program designed to efficiently teach and evaluate acute care skills and teamwork. The Section of Hospital Paediatrics initiated the jIT program in 2012 with support from the KidSim program. jIT sessions are designed and led by the CTU teaching fellow with mentorship from a hospital pediatrician. Sessions are especially brief and dynamic consisting of a 5 minute orientation, 10 minute

� Group shot of several

members of the Section of Hospital Paediatrics

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Department of paeDiatrics | annual report 201334

scenario and 15 minute debriefing period. jIT scenarios are based on current in-patients who are at highest risk for deterioration. The patient’s very own inter-disciplinary healthcare team (including the senior resident, junior residents, medical students and the patient’s nurse) form the participants for the session. jIT gives the multi-disciplinary team the opportunity to simulate the anticipated pattern of deterioration (i.e.: respiratory distress, decreased LOC, hypovolemic shock, septic shock, seizure, etc) of a high-risk current in-patient. The team is therefore able to rehearse targeted assessment and specific management strategies for the real in-patient thus bringing simulation education to the point of care!

� Group shot of several members of the Section of Hospital Paediatrics

� Dr. Lindsay Long – Intubating a simulation subject. The team from the JIT (Just in Time) program

Here are some examples of what jIT participants say about the sessions …

“Our learning was so relevant because the scenario was based on one of our real patients.” CTU Resident

“It is helpful to practice as a multidisciplinary team because this is how we perform in real life. I also like that the sessions are very brief – this makes it possible to integrate this valuable learning into our regular work day.” RN

���

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s p e c i a l f e a t u r e

ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 35

The KidSIM Pediatric Simulation Program has been training health care professionals both as individuals and as part of interprofessional teams since October of 2005. Since that time, the KidSIM Program has grown significantly and is responsible for the training of approximately 3,500 learners per year. These learners come from all levels of training, from undergraduate learners all the way through to practicing health professionals. They come from diverse backgrounds, everything from rural EMS providers to operating room nurses to attending pediatric intensivists, among many others. The KidSIM program works to provide learners surrogate clinical experience with pediatric patients in as close to a ‘real-life’ situation as possible through the use of high-fidelity mannequins as well as teaching space that mimics the clinical setting as closely as possible. In doing so, it is hoped that the learners experience the pressure and stressors of the real situation, as they work as individuals and in teams, in order to learn more about the assessment and management of these cases. This realism is further enhanced by moulage of the patients, providing the real results of tests and adding personnel to the case to act in various roles (parent, consultant, etc). Evaluation of the scenarios and of the program as a whole are overwhelmingly positive, with a common theme being the request for more and more sessions. In the first 6 years of the program, there has been incredible growth in the number and diversity of learners, as well as growth in the number of areas incorporating simulation into their overall education plan.

KidSIM™ Pediatric Simulation Program at Alberta Children’s Hospital

The mission of the KidSIM Program is to support interprofessional education by working together with physicians, nurses and allied health care providers to ensure optimal accessibility, innovation, leadership and excellence in pediatric experiential learning and simulation education. Simulation is an essential component to meet current and future demands related to healthcare education, experiential learning, team crisis resource management, patient safety, workforce utilization, and clinical research.

Since 2005, the program has grown from one mannequin, one basement laboratory at the former ACH site, and a handful of trained educators to one of the broadest and busiest pediatric simulation programs in the world. Through on-going support from the Department of Pediatrics and the ACHF, the program now boasts greater than 80 trained simulation education facilitators, 10 high-fidelity mannequins spanning infancy to adolescence, two simulation laboratories in the new ACH, and very soon a 3,600 square foot simulation centre on the 4th floor of the new ACH. The KidSIM Program has been involved in the delivery of high quality interprofessional pediatric simulation education to over 3,500 learners per year, from undergraduate learners to practicing health care professionals, both at the Alberta Children’s Hospital site, as well as via mobile education to providers in the broader Calgary community, and regional and rural healthcare providers in Southern Alberta and Southeastern British Columbia. ���

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DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201336

was recruited specifi cally for its strength in centralized tertiary care of children with tropical diseases as a result of immigration and travel. Currently there is only one other GeoSentinel site in the global network with a pediatric specialist as director.

One of the most notable related clinical highlights was something that didn’t make the news: the successful prevention of a measles outbreak through the quick recognition of an imported case, rapid organization and implementation of screening of over 500 exposed persons (patients, staff, healthcare workers, and others), and appropriate intervention strategies for those determined susceptible. The latter highlight illustrates how the biggest success stories are the ones no one knows about! ���

Section of infectious Diseases

HIGHLIGHTS

The highlight of the past year for the Section of ID is the expansion and increased profi le of our research and clinical activities related to vaccine preventable diseases. The Alberta Children’s Hospital Infectious Diseases, Epidemiology and Vaccine Evaluation Research Team (ACHIEVE; http://www.ucalgary.ca/achieve/), has added a multicentre clinical trial of pertussis vaccine in pregnant women, a Canadian study of HPV vaccine effi cacy in young women, in addition to its ongoing projects in pneumococcus (CASPER), infl uenza (PCIRN), meningococcus, and the work of section members studying hospitalized patients with various vaccine-preventable diseases through IMPACT .

As a result, ACHIEVE is increasingly recognized as an important contributor to knowledge in vaccine preventable diseases both nationally and internationally. The research team is also steadily building partnerships with colleagues in specialties such as emergency medicine, gastroenterology, and rheumatology in order to address common concerns in vaccine-preventable diseases.

A new component of the research portfolio in 2012 was the addition of imported infectious diseases, when Calgary became the newest site of GeoSentinel Global Surveillance Network (www.istm.org/geosentinel/main.html). As the sixth site in Canada (one of 57 around the world), Calgary

PHySICIaN/FaCulTy lISTINg:

Dr. Susan Kuhn*- Section Chief

Dr. Rupesh Chawla*- PGME Program Director

Dr. Taj Jadavji

Dr. James Kellner- Department Head

Dr. Mireille LeMay

Dr. Otto Vanderkooi

Dr. Joseph Vayalumkal

� The faculty of Infectious Diseases left to right: Dr. Rupesh Chawla, Dr. Mireille LeMay, Dr. Jim Kellner, Dr. Taj Jadavji, Dr. Joseph Vayalumkal, Dr. Susan Kuhn,Dr. Otto Vanderkooi

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 37

HIGHLIGHTS

35 years of genetics at ACH, and over 55,000 families seen.

The Genetics Clinic was started in 1977 by Dr. R. B. Lowry as an integral part of the Alberta Hereditary Diseases Program (AHDP). The staff consisted of himself, a nurse and a medical secretary. The clinic was originally housed in the Kinsmen Research Building at the old Alberta Children’s Hospital site. In an era where genetic testing consisted of a mere karyotype and molecular analysis had yet to be developed, patient charts were tracked using rolodex cards. These cards are now archived although still require occasional consultation as subsequent generations seek our services. The rapid rate of gene discovery and the development of new genomic technologies are being accompanied by an increasing number of referrals. Our clinic now has a comprehensive scope of genetics services from prenatal genetics, pediatric genetics and metabolic genetics to adult clinics including neurogenetic, oncogenetic and cardiogenetic patients. A key component of the original AHDP was the outreach service, which has provided uninterrupted clinics to Lethbridge, Medicine Hat and Red Deer for over 30 years.

Our clinics are now staffed by over 60 individuals including physicians, genetic counsellors, nurses, dieticians, psychologists and administrative support personnel. In 2013 we saw our 59, 000th family from Southern Alberta!

PHySICIaN/FaCulTy lISTINg:

Dr. Francois Bernier – Section Chief Department of Paediatrics, Faculty of Medicine, Department of Genetics

Dr. Mary Ann Thomas – PGME Program Director

Dr. Aneal Khan – Medical Director, Metabolic Clinic

Dr. Robin Casey

Dr. Patrick Ferreira

Dr. Michael Innes

Dr. Julie Lauzon

Dr. Brian Lowry

Dr. Ross Mcleod

Dr. Renee Perrier

Dr. Rebecca Sparkes

� Dr. Brian Lowry ca. 1980 and now December 2013.

Section of medical Genetics Department of Paediatrics, Faculty of Medicine, Department of Genetics

We are now on the brink of a revolutionary change in genetics as whole genome sequencing begins to be implemented into clinic care, ushering in the era of genomic medicine. None of us can predict what the next 35 years will bring. ���

� Section of Medical Genetics ca. 1992 and now December 2013.

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Department of paeDiatrics | annual report 201338

Section of neonatology

HIGHLIGHTS

Select Clinical Services stats

• Mean length of stay (LOS) for NICU’s = 10.7.

• Total admission to Calgary NICU’s = 3157.

• Responsible for 34 Level III beds at the Alberta Children’s Hospital (ACH) and Foothills Medical Center (FMC), and 89 Level II beds at the FMC, Peter Lougheed Center (PLC), South Health Campus (SHC), and Rockyview General Hospital (RGH).

• Total transports and transfers within the Southern Alberta Network = 708.

Clinical Care

• Construction for the new 14 bed Edwards Family NICU continues to progress. you can see the full update on this in the feature on page XX.

• The functional program for the PLC Women’s Health Redevelopment Project which includes a new Family Centered 30 room Level II NICU with a capacity for 36 babies was completed; our thanks to Maciej Burzynski, Senior Project Manager, Alberta Infrastructure, Capital Projects, Health Facilities Branch.

• Dr. Deborah Clark, Chair, Neonatal Coordinating Committee: this committee has expanded its membership in the last year to ensure a more multidisciplinary review of all items brought forward for discussion. Membership now includes: 7 neonatologists each of whom chairs a Clinical Working Group; 1 neonatologist who chairs the Quality Improvement Committee; 1 Quality Improvement nurse; 1 webmaster (RN); 1 clinical nurse manager; 1 clinical nurse educator; 2 Neonatal Nurse Practitioners (both are representatives on Provincial Working Groups); One NNP is responsible for monitoring/guiding the development of suitable parent handouts where required; 1 Registered Respiratory Therapist

Clinical Working Groups: The number of these has also expanded and the chair of each provides a report of current activities to the Coordinating Committee. Original Clinical Working Groups struck were for CNS, CVS, Respiratory, Surgery and GI issues. This year, we have added an Infection Prevention Group, a Palliative Care Group, a Discharge Planning/Parent Education Group and an Oral Feeding Group

Clinical Practice Guidelines Reviewed and Approved = 13.

Educational Handouts Reviewed and Approved = 5

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 39

PHySICIaN/FaCulTy lISTINg:

Dr. Ayman Abou Mehrem

Dr. Albert Akierman – Interim Section Chief

Dr. Essa Al Awad – PLC NICU Site Leader/Under-Grad. Education

Dr. Belal Alshaikh – Locum Neonatologist

Dr. Harish Amin – SHC NICU Site Leader and Paediatric Medical Site Lead

Dr. Jill Boulton – Quality Assurance Lead

Dr. Deborah Clark – RGH NICU Site Leader

Dr. Carlos Fajardo - Data Coordinator

Dr. Andrei Harabor – Functional Echo Lead

Dr. Shabih Hasan

Dr. Leonora Hendson

Dr. Alixe Howlett – ACH NICU Site Leader

Dr. Majeeda Kamaluddeen – Program Director, Neonatal Perinatal Medicine

Dr. Abhay Lodha – Chairman, Continuing Medical Education

Dr. Jack Rabi – Chair, Finance Committee/SCM

Dr. Nadira Rashid – Locum Neonatologist

Dr. Reg Sauve – Director, Neonatal Follow Up Clinic

Dr. Nalini Singhal

Dr. Amuchou Soraisham –

Coordinator, Post -Graduate Education (Paediatric Residents)

Dr. Amelie Stritzke

Dr. Sumesh Thomas – Medical Director, Neonatal Transport Team

Dr. Anne Tierney – FMC NICU Site Leader/Interim Deputy Chief

Dr. Wendy Yee – Quality Assurance Coordinator

Dr. Kamran Yusuf – Director, Neonatal Research

� Group photograph of several members

of the Section of Neonatology

Quality Improvement:

The Neonatal Quality Improvement Committee (NQIC) meets monthly, co-chaired by Stacey Dalgleish BN NNP and Wendy yee MD. Quality improvement initiatives have continued in the areas of infection prevention, respiratory management of VLBW infants, supporting breast milk/human milk feeding in NICU infants, supporting skin-to-skin care for NICU infants, developmentally appropriate feeding advancement, age-appropriate developmental care of NICU infants and discharge planning. A multi-disciplinary delegation of providers from the regional NICUs attended a Quality Improvement Conference (Evidence-based Practice for Improving Quality – EPIQ Conference) in Toronto, Ontario in February 2013, with funding support from the Section of Neonatology. The group presented several invited talks. ���

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ACH Neonatal Intensive Care Unit (NICU) update November 2013

Construction for the new 14 bed edwards Family NICu continues to progress. After a design process which involved all the stakeholders, including the Edwards family, past families of NICU babies, ACH and FMC staff and AHS, construction began in January 2013.

As the construction progressed, a mock up NICU room was made to allow for patient care simulations to occur with the help of KidSim and Human Factors. These simulations provided valuable information about the function of the new space and small modifications were made as construction progressed. Portions of the administrative space have been completed and have opened.

Construction completion and operational commissioning of the clinical space will occur simultaneously in the beginning of 2014, followed by staff orientation. The NICU is expected to be open for patient care at the end of February 2014. ���

DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201340

s p e c i a l f e a t u r e

� �

NICU Mock Up Room and main corridor.

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 41

Section of nephrology

200+ children in Southern alberta coping with moderate or severe kidney insufficiency, those on dialysis or those who have received kidney transplants. although this is only about 15% of the children seen it reflects well over 35% of the physician and clinic resources.

HIGHLIGHTS

The Section of Nephrology has undergone some workforce challenges this past year with the start of Dr Silviu Grisaru's sabbaticals coinciding with the departure of Dr Tee to Halifax at the end of june. However the section has still been able to continue providing important clinical care to children and their families.

Like many of the clinical sub-specialities at the Alberta Children’s Hospital, the vast majority of clinical work is provided in the nephrology outpatient clinic.

This clinic attends to approximately 1500 families per year with over 3000 clinic visits.

Of highest complexity are the 200+ children in Southern Alberta from families coping with moderate or severe kidney insufficiency, those on dialysis or those who have received kidney transplants. Although this is only about 15% of the children seen it reflects well over 35% of the physician and clinic resources.

Monitoring progress with regular clinic visits, blood pressure control and blood chemistry analyses together with attention to growth helps to delay or even prevent dialysis or transplantation. In 2013 four children received a kidney transplant, the youngest being just 2 years of age, bringing the total transplanted at the Alberta Children's

PHySICIaN/FaCulTy lISTINg:

Dr. Julian Midgley - Section Chief, CME director and UME Deputy Program Director

Dr. Lorraine Hamwika - PGME Program Director

Dr. Silviu Grisaru

Dr. Susan Samuel

Dr. James Tee

Dr. Andrew Wade

Hospital over several years to 56 with the majority receiving living donor kidneys (most from a parent). The care of these patients now extends into adulthood as the section actively participates in the young Adult Transplant Clinic at the Foothills Hospital. This represents a significant improvement in transition to adult medical care which has been championed by the section with the organisation of the Transition Symposium.

The nephrology team are proud of the work they do and the difference they make to children and families with kidney disease. ���

Dr. Susan Samuel

� From left to right: STAFF: Dr. Wade, Dr. Samuel, Dr. Midgley, Dr. Hamiwka, Dr. Grisaru (back row) NEPHROLOGY RESIDENTS: Dr. Alsaidi, Dr. Banks, Dr. Alghamdi (front row)

85%15%

Children withmoderate

to severe kidneydisease or those

on dialysis orwith renal

insu�ciency

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Increasing numbers of youth with special health care needs are transferred from pediatric health care to adult oriented health care settings each year. It is well recognized that the process of transitioning and transferring to adult-centered care is challenging for adolescents, young adults and their families. While some patients transition well, too many cope poorly and fail to access quality care - leading to devastating consequences.

Provision of uninterrupted, developmentally appropriate and coordinated care is necessary to ensure best health outcomes in transitioning youth. We convened a one-day symposium to discuss challenges and opportunities to improve transitional care within the Calgary zone in November 2012. A wide range of clinical groups caring for youth and young adults with special health care needs participated in the symposium and registrants totalled over 170 clinicians, researchers and administrators. We prepared and distributed a report summarizing the outcomes of the symposium and recommendations for improving transitional care for youth with special health care needs in Alberta. Visit this page for the entire Transition Symposium report: http://issuu.com/ach_paediatric_department/docs/transition_symposium_report_oct_29_

The most significant recommendations in the symposium report are as follows:

1. Youth with special health care needs should have a family physician identified well before transfer of care.

Transition Symposium

2. Youth with special health care needs should have individualized transition plans which incorporate elements of successful intervention strategies (improved education and self-management skills, access to transition coordinator in pediatric care, transition clinics, system navigator support in adult care).

3. A method for evaluating the outcomes of patients transferring from pediatric care should be developed.

4. Ensure consistency of transitional care across disciplines and, in particular, provide support for programs which are in desperate need of better transitional care (e.g. mental health services for youth and young adults with special health care needs).

Alberta Health Services needs a coordinated strategy to improve transitional care. A smooth coordinated transition will ensure that all children have the best opportunity to achieve their full potential in adulthood. Best transition practice encourages graded medical independence and self-management skills. A well planned and executed transition strategy will reduce health systems costs by decreasing complications and improving health outcomes. Implementing recommendations in the symposium report will require commitment from Alberta Health Services, Alberta Health and all front line clinical programs. ���

s p e c i a l f e a t u r e

DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201342

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 43

Section of neurology

OVERVIEW: The Section of Pediatric Neurology based at the Alberta Children’s Hospital (ACH) provides neurological care to the children of southern Alberta and neighbouring Saskatchewan/British Columbia. Dr. jong Rho leads a dozen faculty child neurologists and an extensive team of trainees and allied health professionals. Excellence in clinical care and research spans all elements of child neurology including: Epilepsy, Neurotrauma and Stroke, Headache, Demyelinating & other Neuro-immune Conditions, Neonatal Neurology & Brain Malformations, Neuromuscular & Movement Disorders, as well as Developmental & Cognitive, Neurogenetic & Metabolic Disorders.

CLINICAL CARE: Round-the-clock urgent care is provided through inpatient on-call service and outpatient urgent neurology clinics. Integrated collaborations across multiple paediatric specialities provide comprehensive, cross-disciplinary care. ACH Pediatric Neurology cares for over 700 inpatient consults annually. Outpatient clinics have increased to nearly 5,000 family visits per year including general neurology and numerous subspecialty clinics. Multiple clinical innovation projects and quality improvement/assurance initiatives have been regularly implemented.

EDUCATION: Our RCPSC Residency Training Program remains fully accredited, has grown to 7 residents (among the largest in Canada) and continues to maintain a

PHySICIaN/FaCulTy lISTINg:

Dr. Jong M. Rho - Section Chief

Dr. Karen Barlow

Dr. Luis Bello-Espinosa

Dr. Anita Datta

Dr. Michael Esser - PGME Program Director”

Dr. Laura Flores-Sarnat

Dr. Heather Graham

Dr. Robert Haslam

Dr. Alice Ho

Dr. Adam Kirton

Dr. Jean Mah

Dr. Aleksandra Mineyko

Dr. Alison Moore

Dr. Harvey Sarnat

Dr. Morris Scantlebury

Dr. Kim Smyth

� FromFaculty from left-to-right: Jeffrey Buchhalter, Morris Scantlebury, Harvey Sarnat, Karen Barlow, Adam Kirton, Laura Flores-Sarnat, Luis Bello-Espinosa, Alice Ho, Michael Esser, Jong Rho; not pictured: Jean Mah, Alison Moore

100% success rate on the Royal College exam. All section members are actively engaged in teaching through undergraduate, medical school, residency, graduate student, and post-doctoral fellowship levels. A rich educational environment now includes >10 academic rounds and conferences per week.

RESEARCH: Supported by the Alberta Children’s Hospital Research Institute (ACHRI) for Child and Maternal Health and the Hotchkiss Brain Institute (HBI), our Section continues to experience significant academic growth. Major operating and program grants are held from agencies including CIHR, NIH/NINDS, AIHS, HSFC, NeuroDevNet, CPIRF, and ACHRI. Further, multiple knowledge translation initiatives have directly impacted the clinical care of families.

HIGHLIGHTS INCLUDE:

• >$1.5million in active external funding (brain metabolism, neurotrauma & stroke programs)

• >40 peer-reviewed original papers, >12 book chapters, and >80 scientific abstracts

• >30 invited presentations at major national / international meetings

• >200% growth in research trainees across diverse levels and disciplines

���

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DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201344

HIGHLIGHTS

The Calgary Childhood Traumatic Brain Injury Program is a comprehensive clinical assessment, treatment and rehabilitation program. Our mission is to provide exceptional care for children with Traumatic Brain Injury and Complex Concussion. Our goals are to facilitate access to health care, enhance community and educational integration and ultimately improve long-term outcomes.

Traumatic Brain Injury is the commonest cause of neurological disability and aff ects as many as one in fi ve children before the age of 16. Every year the Alberta Children’s Hospital treats over 1500 children with TBI. Many of these children have a mild TBI, often called concussion. A brain injury is often called a “silent” injury, as usually there are few external signs of an injury or trauma and motor recovery is relatively good. This means that they look the same as everyone else. However, many children have severe and frequent headaches, mood and personality changes, diffi culties at school (often with an odd mix of abilities and disabilities) and perhaps most importantly they have great diffi culty making and sustaining friendships.

Our program spans from the Emergency Room, Inpatient Unit, Gordon Townsend Rehabilitation School, to the Traumatic Brain

Injury and Calgary Complex Concussion Clinic (TBI and 4C clinic). We also have an outreach component that extends to schools and the community. We are a multidisciplinary inpatient and outpatient team of health care professionals, clinicians, educational consultants and researchers. This allows us to provide the necessary complex care to this highly variable group of children and their families.

As with many programs, the bulk of our work is in the outpatient clinic and we run 3-4 outpatient clinics and one neuropsychological diagnostic clinic per week. Our outpatient team includes neurologists Dr. Karen Barlow and Dr. Mike Esser, Dr. Vithya Gnanakumar (physiatry), Lisette Lockyer and Sarah Shantz (nurse practitioners), Lisa Bodell (TBI clinic nurse), Carol Johnson (school liaison) and Brian Brooks (neuropsychology). We collaborate with schools, university sport medicine clinics, mental health services and community professionals so that over time children can integrate into society to their fullest potential.

In addition to an extensive clinical program, we believe that research is crucial to improve outcomes for children and families. At the very heart of this program lies clinically meaningful translational research and education.

Dr. Karen Barlow is the operations and research director of the clinical program at the Alberta Children’s Hospital. Our

Calgary Childhood Traumatic Brain Injury Program

s p e c i a l f e a t u r e

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ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 45

research focuses on several areas including the assessment and management of complex concussions and TBI, including social functioning, the exploration of novel biomarkers, as well as outcomes from pharmaceutical and non-pharmaceutical treatment trials. In this regard, Dr. Barlow has recently been awarded a CIHR team grant to perform a randomized placebo-controlled treatment trial for children who have persistent post-concussion symptoms at one month post-injury called the Play Game Trial (Post Concussion Syndrome in Youth: the GABAergic effects of Melatonin).

Computerized and novel assessment methods are also being explored in the TBI 4C clinic. These assessments include rapid neuropsychological testing (especially for children complaining of memory impairment), and vestibular and balance testing with a view to providing easy and rapid assessment tools for community practitioners.

With the recent appointment of Dr. Michael Esser as a clinician-researcher in Neurotrauma we not only enhanced clinical capacity for the TBI program but also now have an established translational TBI laboratory in ACHRI. This laboratory is focused on gaining a better understanding of the fundamental factors that affects outcomes in pediatric brain injury using the principle of basic science modeling linked to clinical biodiagnostics. This is

Dr. Karen Barlow, photo courtesy of Riley Brandtl

an exciting expansion of our program as the laboratory is the first of its kind in Western Canada and one of only a few in Canada, which allows us to bring true bedside-bench-bedside research to pediatric TBI in Calgary. ���

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Department of paeDiatrics | annual report 201346

Section of oncology

HIGHLIGHTS

The Division provides compassionate and comprehensive care to general- and neuro-oncology patients, to children undergoing hematopoietic stem cell transplant (SCT), and to long-term survivors of childhood cancer and SCT therapy. In the academic year 2012-2013 we were well staffed, and advanced our clinical, education and research programs. All of our work is in partnership with the multidisciplinary, multiprofessional Hematology, Oncology and Blood and Marrow Transplant Program of Alberta Children’s Hospital. We are generously supported by the Alberta Children’s Hospital Foundation, the Childhood Cancer Collaborative and Kids Cancer Care Foundation of Alberta.

The research lab or Dr Aru Narendran was officially designated as the POETIC Lab for Pre-Clinical and Drug Discovery at the University of Calgary. It plays a fundamental role in most of the POETIC clinical trials of new agents.

Members of the Division hold several leadership roles in national and international consortia: Drs Lafay-Cousin, Guilcher, Strother and Lewis in the Children’s Oncology Group; Drs Strother and Lewis in C17; Dr Narendran in POETIC. As well, within administration, Dr Anderson

PHySICIaN/FaCulTy lISTINg:

Dr. Doug Strother – Section Chief

Dr. Ron Anderson

Dr. Greg Guilcher

Dr. Lucie Lafay-Cousin

Dr. Victor Lewis

Dr. Aru Narendran

Dr. Kathy Reynolds – Long-term/Follow up clinic

Dr. Tony Truong

holds the position as Deputy Director, Education, Department of Pediatrics.

We welcomed Dr Gurpreet Singh as a Paediatric oncology clinical associate. Dr Singh completed Paediatric heme/onc training with us in june 2012.

An pilot initiative with Alberta Health Services called Hospital at Home was initiated to provide selected outpatient clinic care in patients’ homes. This program was funded through the Childhood Cancer Collaborative (CCC). Hospital at Home is meant to reduce the costs of care that families accumulate during months’ long cancer care, and to reduce the burden of care within our limited clinic space. Evaluation of the pilot project is underway.

Current Issues

Challenges for the year included 1) our limited outpatient clinic and day-treatment area spaces within the clinic space that we share with Paediatric hematology, immunology and allergy; 2) evaluation of programs newly instituted or augmented through the Childhood Cancer Collaborative; and 3) transition of support of CCC initiatives to Alberta Health Services in an environment of limited resources.

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 47

Research Highlights

Division members contributed to a record number of peer-reviewed publications. The number of research studies onto which we accrue patients is also at an all-time high. The 3rd Annual Paediatric Oncology Research Day was held in November in at Hotel Alma. This year the day incorporated oral presentations of research proposals that competed for funding by the Kids Cancer Care Research Chair.

Dr Narendran is a member of the Conjoint Health Research Ethics Board, a duty that involves considerable time for scientific and ethical review of research proposals.

Program

We provide care to patients in four broad areas: general oncology, neuro-oncology, blood and marrow transplant and long-term survivorship.

University of Calgary Endowed Chair

Under the Kids Cancer Care/ Alberta Children’s Hospital Foundation Chair in Paediatric Oncology, a competition was held for research grant funding. Drs. Carol Schuurmans, Kathy Reynolds, Nancy Moules

and Nicole Culos-Reed were awarded funding for their respective proposals.

Education Programs

All of the physicians in the Division provide teaching to medical students and Paediatric residents in the in- and outpatient oncology settings. Undergraduate honours students and candidates for Master’s and Doctoral degrees are supervised by members of the Division. Dr Narendran supervises postdoctoral students in his laboratory. As well, all members contribute to the education and evaluation of subspecialty residents in the Paediatric Hematology Oncology Training Program at Alberta Children’s Hospital. Drs Ravi Shah and Anjali Kamra commenced training on july 1, 2012. ���

� From left to right: Dr. Tony Truong, Dr. Ron Anderson, Dr. Lucie Lafay-Cousin, Dr. Greg Guilcher, Dr. Doug Strother, Dr. Victor Lewis

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Department of paeDiatrics | annual report 201348

Section of palliative care

HIGHLIGHTS

The Children’s Hospice and Palliative Care Service (CHaPS) continues to provide comprehensive palliative care to children with serious illnesses and their families, at all the acute care sites in Calgary Zone, in the community and at Rotary Flames House. We also provide respite stays at Rotary Flames House to give parents short breaks from the intensive medical care they need to provide to their children 24/7 in their own homes. A new initiative has been the development of day programming specifically designed for children with progressive life threatening conditions. This includes pet visits, music groups, day trips and many other recreational opportunities. Such activities are readily available for healthy children and their siblings but much less accessible to children who are medically fragile.

We have continued to care for many dying children and their families. Our grief support coordination and bereavement service has been particularly active this year with the development of new bereaved parent groups as well as continuing to provide one on one counselling for many. The bereavement service is offered to all parents who have suffered the death of a child who has in any way been connected with ACH during their life time.

Section Members provided service on many committees at ACH and have been increasingly involved in providing

PHySICIaN/FaCulTy lISTINg:

Dr. Marli Robertson - Section Chief

Dr. Mala Arasu

Dr. Leonie Herx

Dr. Kevin Levere

Dr. Sharron Spicer

leadership to increase awareness and understanding of palliative care for children and to improve the care of children with life threatening medical complexity at a Provincial and National level.

• Department of Paediatrics Residency Training Committee ( Member)

• ACH Ethics Committee ( Member)

• ACH Safety committee ( Member)

• ACH Quality Committee (Chair)

• AHS Provincial Steering Committee for Palliative and End of Life Care

• AHS Advanced Care Planning Policy and Process Committee

• Canadian Network of Palliative Care for Children ( Executive member)

• Canadian Network of Pediatric Hospices (Executive Member)

• CAPH-C Community of Practice for Children with Medical complexity – Member

• Canadian Society of Palliative Care Physicians ( Executive)

• Royal College Conjoint Advisory Committee for Palliative Medicine ( Members). ���

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 49

Our own Dr. Ian Mitchell accepted both the Calgary Medical Students’ Association Gold Star Award for Exceptional Classroom Instruction in Ethics as well as the prestigious William Marsden Award from the Canadian Medical Association for his legacy in medical ethics.

The Section continues to provide comprehensive Sleep testing and Pulmonary Function Testing to most of the Southern Sector. ���

Section of respirology

HIGHLIGHTS

The Section of Respiratory Medicine had a great 2013 with major changes either completed or newly implemented in almost all of our clinics.

The Asthma team continues to roll through 2013 with a new clinic at the South Health Campus.

The Sleep team has developed internally an innovative model in clinic to allow the allied health professionals, (nurses, respiratory therapists and sleep technologists) direct interaction with patients under supervision of the Sleep Physician. This model has had a tremendous effect on our clinic waiting list.

The Pulmonary clinic is now re-booking patients in “real-time” decreasing missed return appointments and increasing clerical efficiency.

The Cystic Fibrosis clinic underwent successful accreditation from CF Canada.

The Respiratory Home Care Clinic has continued to provide excellent care to the most complex and fragile patients.

The Section has initiated a joint venture in having a respirologist attend Sickle Cell Clinic to minimize the number of visits for those families.

PHySICIaN/FaCulTy lISTINg:

Dr. Mark Anselmo – Section Chief

Dr. Marielena DiBartolo – PGME Program Director

Dr. Michelle Bailey (Primary appointment in Hospital Paediatrics)

Dr. Candice Bjornson

Dr. Glenda Bendiak

Dr. Valarie Kirk – Deputy Department Head

Dr. Ian Mitchell

Dr. Mary Noseworthy

� Mahir Ahmed Abdulla undergoing spirometry testing, a type of pulmonary function testing that is particularly useful for diagnosing asthma.

polysomnography

500+ overnight studies,

in children, in one of 4 bed laboratories

Pulmonary Function Tests

3452 per year in the areas of

Spirometry, Lung Volumes etc.

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DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201350

Asthma Program

s p e c i a l f e a t u r e

DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201350

Pediatric asthma in the Calgary Zone (with >45,000 affected) is a collaboration between the Community Pediatric Asthma Service (CPAS), Asthma Specialty Clinic (ASC), Pulmonary Function Testing Lab at Alberta Children’s Hospital (ACH), the Department of Family Medicine (DFM), Community Pediatrics and the Respiratory Clinical Network (RCN) (“the TEAM”). Asthma is the most common chronic disease of childhood.

TEAM Improvements:

• Onlinedevelopment/implementationofRCNprovincialpediatric asthma pathways

• NewreferralformfortheZone(triage,transferanddischarge guidelines)

• DFMresidentasthmaeducationwithCPASpartnership(2012-2013)

• PediatricAsthmawebsitewitheducationinformation/tools/demos in 13 languages and 100,000 hits in 2010

• Asthmadatabasecapacityforrealtimedeliveryofpersonlaized action plans and prescriptions

TEAM Outcomes:

• Reduction to #9th reason for emergency visit and #7th reason for admission (Annual Child Heath Report

2011/2012) despite a 13% increase in the Zone pediatric population since 2005

• RCNasthmapathwayImplementationresultedina90%increase at ACH and 60% in all other facilities in MDI/Spacer use – a best practice implementation

• ASCappointmentsbookedinrealtime(atendofcurrent visit), enchancing clinic efficiency and family satisfaction

TEAM Achievements - Provincially, Nationally and Internationally:

• RCN received the Alberta Health Services Presidents Excellence Award in Research 2013

• Sixoralpresentationsatthe21stWorldCongressofAsthma in Quebec City

• Zonepediatricasthmapathways(RCN)developmentledtothe first provincial pediatric pathway for ER implemented online across pilot Alberta Emergency Departments in 2013 – the first in Canada

• CPAScoordinator,ShirleyvandeWeteringBScMBA,was one of only 2 recipients of the Alberta Medical Association’s 2012 Medal of Honor, its highest honor for non-physicians. ���

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 51

Section of rheumatology

HIGHLIGHTS

The Section of Rheumatology had an outstanding academic year.

We are very proud to report that we increased our (wo)man power and have grown to five physicians.

Early this fall, we had a very successful retreat resulting in an innovative care model for in and outpatients in Rheumatology, which we are aiming to implement along with the nursing team in january 2014.

Furthermore, we successfully completed the first important step of University of Calgary approval for our urgently needed Paediatric Rheumatology Residency Program. A huge thanks to all of you in the different sections, to Pam and Allison our fearless admin team and the leadership at ACH for guidance and support.

We have and will continue to reach out to the many brilliant clinicians, educators and researchers at ACH for joint care models, cross-disciplinary educational events and collaborative research endeavors. Our

PHySICIaN/FaCulTy lISTINg:

Dr. Susa Benseler

Dr. Nicole Johnson

Dr. Heinrike Schmeling

Dr. Tommy Gerschman (locum tenens)

Dr. Nadia Luca

Dr. Paivi Miettunenclinical and translational research programs including neuroinflammation, morphea, systemic vasculitis and lupus, transition, early arthritis and autoinflammation are a tremendous source of learning hopefully resulting in patient outcomes.

We are also closely aligned with our fantastic adult rheumatology colleagues led by Dianne Mosher. For years, we have worked together with young adults who have rheumatic diseases at the (yARD) clinic. More recently seed for new joint initiatives have been laid. Together, we hold superb educational rounds and are engaged in important research in rheumatic disease. ���

� Dr. Nadia Luca, Dr. Paivi Miettunen, Dr. Heinrike Schmeling, Dr. Nicole Johnson, Dr. Susa Benseler

Page 54: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201352

Research Unit - Behavioural research Unit

HIGHLIGHTS

Dr. Gerald Giesbrecht - Alberta Pregnancy Outcomes and Nutrition (APrON)

What a pregnant woman eats and drinks and the chemicals she is exposed to have direct effects on her baby’s development. That much seems obvious. But what about the impact of her psychological and social experiences? Do feelings of depression and anxiety or the secure feeling of being loved and supported somehow become incorporated into a baby’s biology? If so, how are these ‘stress signals’ transduced from a woman’s experiences into her baby’s development and why are not all babies affected equally? These are the kinds of questions that Dr. Gerry Giesbrecht is investigating in a series of studies based on the Alberta Pregnancy Outcomes and Nutrition (APrON) cohort. So far the results have provided crucial evidence linking pregnancy stress to increases in cortisol which then seems to put baby’s stress systems into overdrive.

It has been widely reported that pregnant women become less reactive to stress as pregnancy progresses and that this reduction in stress reactivity is a protective mechanism that shields the baby from maternal cortisol. Dr. Giesbrecht’s recent work shows that this is not the case: stress-related increases in cortisol are maintained throughout pregnancy. Fortunately, however, there are

FaCulTy lISTINg:

Dr. Deborah Dewey – Unit Chief

Dr. Gerald Giesbrecht

Dr. Bonnie Kaplan

ways to help shield the baby from maternal stress. We know, for example, that social relationships can buffer the effects of stress on child development. Indeed, a recent study conducted in Dr. Giesbrecht’s lab found that women who have highly supportive partners have smaller increases in cortisol when they experience a stressor compared to women with less supportive partners. These changes in maternal stress physiology have implications for the development of her baby. The ultimate aim of this research is to determine both the mechanisms by which maternal stress during pregnancy gets ‘under the skin of babies’ and the ways that we can interrupt or buffer these effects. ���

Page 55: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 53

s p e c i a l f e a t u r e

Global child Health Unit

The creation of the global Child Health unit (gCHu) is a new addition within the department of Paediatrics under the current leadership of co-directors drs. Jean-Francois lemay and dr. Nalini Singhal.

Approximately 65-70 members of the Department have joined the Unit. The first meeting of the GCHU was all about getting the Unit off the ground and as such one of the first orders of business was to resolve the unit’s Mission and Vision.

The goal of the GCHU is to discuss and share ideas about current and future international projects. Provide a venue for likeminded individuals to work together to support clinical, education and research activities.. In addition, the GCHU increase knowledge dissemination in the area of international health. And assist in training the future leaders in global child health.

There is a lot of interest within the Department of Paediatrics amongst GFT, as well as clinical members including Community Paediatricians and Residents.

Currently short and long-term objectives are being developed with input from all interested individuals and there is support to develop some new programs that would involve a cross section of members. A mechanism to support ongoing programs will be developed. The GCHU will work closely with Global Health & International Partners at the Faculty of Medicine and University of Calgary. ���

PHySICIaN/FaCulTy lISTINg:

Dr. Susa Benseler

Dr. Dana Boctor

Dr. Carrah Bouma

Dr. Jenn Brenner

Dr. Adeline Brimacombe

Dr. Jeffrey Buchhalter

Dr. Decker Butzner

Dr. Ciara Chamberlain

Dr. David Chaulk

Dr. Caroline Chee

Dr. Adam Cheng

Dr. Amy Chow

Dr. Suzette Cooke

Dr. Deborah Dewey

Dr. Frank Dicke

Dr. Meagan Doyle

Dr. Julie Fisher

Dr. Charlotte Foulston

Dr. Janis Friesen

Dr. Ben Gibbard

Dr. Vithya Gnanakumar

Dr. Roxanne Goldade

Dr. Jennifer Graham Wedel

Dr. Barbara Grueger

Dr. Anne Hicks

Dr. Matt Hicks

Dr. Sara Jassemi

Dr. Kristen Johnson

Dr. Majeeda Kamaluddeen

Dr. Gurpreet Khaira

Dr. Susan Kuhn

Dr. Linda Loovere

Dr. Paola Luca

Dr. Jennifer MacPherson

Dr. Jean K. Mah

Dr. Danielle Nelson

Dr. Polya Ninova

Dr. Alberto Nettel-Aguirre

Dr. Cheri Nijssen-Jordan

Dr. David Patton

Dr. Bev Prieur

Dr. Ted Prince

Dr. Jack Rabi

Dr. Nipunie Rajapakse

Dr. Dan Ross

Dr. Amonpreet (Preet) Sandhu

Dr. Reg Sauve

Dr. Anna Serebrin

Dr. Gurpreet Singh

Dr. Nalini Singhal

Dr. Amuchou Soraisham

Dr. Amelie Stritzke

Dr. Heather Thompson

Dr. Joseph Vayalumkal

Dr. Andrew Wade John Wu

Dr. Melanie Willimann

Dr. Karin Winston

vISION: A World Where

Children Can

Survive And Thrive

MISSION: Collaborating To

Promote Global

Child Health Through

Innovative Clinical,

Educational And

Research Activities

Page 56: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201354

Research Team - research methods team

HIGHLIGHTS

A key accomplishment for the Research Methods Team this year is the successful funding in April 2013 of the “Alberta Program in youth Sport and Recreational Injury Program” through the highly competitive Alberta Innovates Health Solutions (AIHS) Collaborative Research Opportunity (CRIO) Program grant competition. We have selected this as a highlight because it is an effort involving all members of the Research Methods Team in collaboration with researchers in other Faculties at the University of Calgary, as well as across Canada. This program is co-led by Dr. Hagel from the Research Methods Team, and Dr. Carolyn Emery (Kinesiology and cross appointed in Paediatrics as well). Drs. Currie and Nettel-Aguirre are also collaborative members of the team. Dr. Hagel’s former trainees also are playing important roles in this CRIO - Former PhD student Dr. Kelly Russell from University of Manitoba is a team member and former MSc student, and RMT research assistant, Nicole Romanow is playing a critical role as Research Coordinator.

About the research program:

In children and adolescents, participation in sport and recreational activity is a key part of maintaining a healthy lifestyle. Childhood physical activity promotes healthy growth and development and prevents chronic disease.

FaCulTy lISTINg:

Dr. Gillian Currie – Unit Chief

Dr. Brent Hagel

Dr. Alberto Nettel-Aguirre

On the other hand, sport and recreation is the leading cause of injury in youth, and many of these injuries require medical attention. The ultimate goal of the Alberta Program in youth Sport and Recreational Injury Program is to reduce the burden of sport and recreational injuries in youth in Alberta.

The specific objectives of the research program are:

1. to develop and evaluate programs and policies in injury prevention in youth sports and recreation focusing on activities with high participation and high burden of injury in Alberta

a. evaluate body checking policy changes in youth ice hockey

b. evaluate age-related participation policies in school ski and snowboard programs and develop and evaluate an injury prevention component to accompany these programs

c. evaluat the effectiveness of a curriculum-based injury prevention program in the junior high school setting.

2. To build research and KT capacity in youth sports and recreational injury prevention. ���

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ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 55

As part of the overall project, we felt it was essential to include a research component by which knowledge would be created regarding the interactions of sleep and epilepsy. To this end, two studies are proposed.

¡ How frequently is epileptiform activity found in small children w ho are referred for a routine sleep study, polysomnogram (PSG)? Does abnormal brain electrical activity or seizures contribute to sleep problems?

¡ How does the sleep cycle relate to abnormal electroencephalographic (EEG) activity and seizures in children that are admitted to the Pediatric Epilepsy Monitoring Unit (PEMU) with regard to respiratory and cardiac function? What are the implications of these relationships to Sudden Unexplained Death In Epilepsy Patients (SUDEP) – an uncommon but devastating complication of epilepsy?

FIRST STEPS: We are systematically reviewing all the polysomnogram studies that we have performed in infants in the

Sleep-Epilepsy Research Project

the sleep-epilepsy integration pilot project was created to test the feasibility of combining the pediatric sleep Diagnostic service and the epilepsy seizure monitoring Unit into an integrated effort for selected children. our hope is to demonstrate more effective and efficient patient care delivery through an innovative approach to the clinical/biological overlap between sleep and epilepsy disorders.

past few years and taking special attention to quantify what sort of sleep problems they were found to have, as well as looking for evidence of EEG abnormalities. Very little is known about sleep physiology in infants and we plan to build on this knowledge.

IMPACT: Our collaborative work will provide further training to both sleep and EEG laboratory physicians and technicians. It will allow for a more systematic process of identifying epileptiform discharge that may prompt referral to the neurology department for further evaluation. It will help us to identify children who may benefit from a combined sleep/EEG diagnostic study from those who need only one of these investigations. The information acquired during these projects could have a direct and immediate effect on the children of Alberta as the rate of SUDEP in those with intractable epilepsy is approximately 1 in 100. Our results could serve as the basis for a trans-Canadian study funded by a CIHR and establish ACH as a world leader in pediatric SUDEP research. ���

s p e c i a l f e a t u r e

THE SLEEP EPILEPSY PROGRAM TEAM: Dr.Alice Ho, Silvia Kozlik, Leah Schmalz, Elizabeth Bourque, Dr. Glenda Bendiak, Adetayo Adeleye, Dr. Valerie Kirk and Jeff Buchhalter (not shown).

Page 58: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201356

Maternal and Child Team - Dr. suzanne tough

HIGHLIGHTS

Education, Research and Service to Society

• Principal Investigator of the All Our Babies Study, a multidisciplinary, collaborative longitudinal cohort of 3,200 maternal child pairs investigating the causes and implications of preterm birth and the early influences of child health and family well-being.

• Completed data collection for AOB participants at age 24 months and completed extensive collaborations and preparation of a new questionnaire for follow-up at 5 years of age, as well as a follow-up questionnaire to investigate the impact of the june floods in southern Alberta.

• Supervised the successful defence of one PhD and one Master’s students, in addition to continued supervision of 5 post-doctoral fellows as well as one new PhD and one new Master’s students, contributing to the training of the next generation of innovative researchers in maternal and child health.

• Continuing as the Scientific Director of the Alberta Centre for Child, Family and Community Research to

FaCulTy lISTINg:

Dr. Suzanne Tough

oversee the development of research and knowledge dissemination activities, ensuring scientific excellence and community relevance, as well as facilitating dialog and partnerships between researchers, policy makers and service providers to promote relevant research and evidence informed decision making.

• Published the Preterm Birth and Healthy Outcomes Team (PreHOT) supplement in BMC Pregnancy and Childbirth featuring 5 articles from the All Our Babies team and an additional 8 articles from other members of the PreHOT tem, representing the culmination of 5 years of team research.

Services Provided:

Dr. Tough has provided service to the University of Calgary, Alberta Health Services, the academic community and the broader community in several significant ways. She participated in a variety of committees that contribute to the knowledge and operations of the Alberta Children's Hospital (n=1), the University of Calgary (n=1) and Alberta Health Services (n=3), including the Alberta Health Services' Women's Reproductive/ Preconception Health Committee.

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 57

Further, Suzanne serves on a variety of international, national and local committees, including: PREBIC (World Health Organization), the Institute Advisory Board for the Institute of Aboriginal Peoples' Health (Canadian Institutes of Health Research, Frontiers of Innovation (a cross-sector, cross-disciplinary collaboration with the Alberta Family Wellness Initiative and the Harvard Center on the Developing Child), the Canadian Child Health Clinician Scientist Program, the Upstart Council of Champions (United Way of Calgary), and the Scientific Advisory Panel for Assisted Human Reproduction Canada Board. She participated as a peer reviewer for professional and salary applications, and for both external and internal grant applications, including the Alberta Innovates Health Solutions Post-Graduate Fellowship Review Committee. Suzanne also serves the health community through ongoing peer reviews of manuscripts submitted to a variety of journals in relevant areas.

Further, Suzanne contributed to the continuing education of investigators, policy makers and the public via invited addresses and workshops (n=5), book chapters (n=3), and peer-reviewed publications (n=19). ���

Page 60: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201358

Paediatric Clinical Activity in Calgary Zone Facilities

Excerpts from Child Health Annual Report 2012/13

Child Health Annual Report 2012/13

ACH Activity - 5 Year Trends

Fiscal Yr 08/09 09/10 10/11 11/12 12/13Discharges 7,075 6,909 7,341 7,344 7,872Total Days Stay (LOS) 38,424 36,897 38,981 40,680 43,902PICU Cases 791 733 780 760 855ED Visits 55,954 59,170 59,639 65,016 72,719Day Surgery 7,050 6,832 6,760 6,960 6,902Ambulatory face to face 225,037 228,531 223,840 238,172 216,146Unique Patients (Inpt & Outpt)* 74,172 76,821 79,863 82,512 87,066Unique patients based on ULI.

April 1, 2012 - March 31, 2013April 1, 2010 - March 31, 2011

7,075 6,909

7,341 7,344

7,872

6,6006,8007,0007,2007,4007,6007,8008,000

Dis

char

ges

ACH Inpatient Discharges

6,0006,2006,400

08/09 09/10 10/11 11/12 12/13

UQIAnnual_F1213_10439.xlsxPage 23

8,000

7,800

7,600

7,400

7,200

7,000

6,800

6,600

6,400

6,200

6,000

08/0

9

09/1

0

10/1

1

11/12

12/1

3

Dis

ch

arg

es

acH inpatient Discharges

7,0756,909

7,341 7,344

7,872

acH activity - 5 year trends

303,610

53%

of the ACH Inpatients Activity by Most Responsible

Physician were under the Department of Paediatrics

Page 61: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 59

Medical Divisions 08/09 09/10 10/11 11/12 12/13

Discharges Total Days ALOS Discharges Total

Days ALOS Discharges Total Days ALOS Discharges Total

Days ALOS Discharges Total Days ALOS

Anesthesiology 1 4 4.0 1 9 9.0 8 25 3.1 6 20 3.3 2 5 2.5Cardiology 49 663 13.5 41 310 7.6 34 345 10.1 44 306 7.0 59 532 9.0Diagnostic Radiology 35 36 1.0 21 31 1.5 14 14 1.0 16 17 1.1 26 27 1.0Endocrinology 54 115 2.1 43 100 2.3 52 118 2.3 88 243 2.8 103 287 2.8Family Medicine 4 133 33.3 3 8 2.7 3 4 1.3 1 3 3.0 5 15 3.0Gastroenterology 141 845 6.0 136 1,014 7.5 145 1,010 7.0 155 973 6.3 140 1,090 7.8Hospitalist/Pediatrics 2,305 14,237 6.2 2,237 14,340 6.4 2,489 16,479 6.6 2,353 15,221 6.5 2,502 15,244 6.1Infectious Disease 15 52 3.5 5 25 5.0 4 26 6.5 8 22 2.8 2 26 13.0Intensivist 249 1,940 7.8 230 1,635 7.1 237 2,992 12.6 184 2,180 11.8 259 2,911 11.2Medical Genetics 12 59 4.9 1 1 1.0 8 12 1.5 1 1 1.0 5 29 5.8Neonatology 69 1,380 20.0 93 2,324 25.0Nephrology 119 589 4.9 109 522 4.8 80 375 4.7 70 378 5.4 133 720 5.4Neurology 93 291 3.1 122 418 3.4 177 473 2.7 223 665 3.0 260 767 3.0Oncology/Hematology 517 4,776 9.2 436 4,230 9.7 480 4,039 8.4 526 4,314 8.2 487 4,023 8.3Psychiatry 355 3,684 10.4 423 4,455 10.5 483 4,203 8.7 433 4,754 11.0 528 6,008 11.4Respirology 91 740 8.1 74 754 10.2 64 669 10.5 48 515 10.7 70 745 10.6Rheumatology 5 9 1.8 11 25 2.3 0 0 4 5 1.3Total - Medical 4,045 28,173 7.0 3,893 27,877 7.2 4,278 30,784 7.2 4,225 30,992 7.3 4,678 34,758 7.4

Department of paediatrics inpatient activity at acH by most responsible physician section

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Department of paeDiatrics | annual report 201360

total paediatric admissions in calgary Zone

08/0

9

09/1

0

10/1

1

11/12

12/1

3

10,000

8,000

6,000

4,000

2,000

ACH-Total (Peds, Sx, MH)

ACH-Pediatrics

PLC-Pediatrics

NICU-Total

Calgary Total Pediatric & NICU

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 61

total Length of stay (Los) Days fo paediatric admissions in calgary Zone

80,000

70,000

60,000

50,000

40,000

20,000

10,000

08/0

9

09/1

0

10/1

1

11/12

12/1

3

ACH-Total (Peds, Sx, MH)

ACH-Pediatrics

PLC-Pediatrics

Calgary-NICU-Total

Calgary Total Pediatric & NICU

Page 64: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201362

< 12 Hr 1 Day (12+ Hr) 2 Days 3 Days 4 Days 5 Days 6 Days 7 Days 8 Days 9 Days 10 - 14

Days 15 - 19 Days

20 - 24 Days

25 - 29 Days

30 - 34 Days

35 - 39 Days

40 - 49 Days

50 - 99 Days

100+ Days

08/09 477 1,931 1,258 819 651 431 286 190 116 87 307 165 92 70 28 59 37 54 17

09/10 452 1,921 1,200 869 560 362 265 229 152 123 338 134 74 58 36 30 31 51 24

10/11 477 2,157 1,284 856 577 400 268 212 171 125 351 174 83 58 30 26 24 42 26

11/12 520 2,110 1,201 857 538 416 287 234 164 109 388 174 103 60 43 25 33 51 31

12/13 520 2,285 1,336 864 600 468 285 254 167 142 403 174 111 65 38 36 28 66 30

0

500

1,000

1,500

2,000

2,500

Dis

char

ges

Length of Stay

ACH Inpatient Length of Stay Trends

Days stay is total number of accumulated inpatient days for patients discharged (including deaths) . The day of admission is counted but not the day of discharge. LOS < 12 hours includes patients in and out the same day or the next calender day.

acH inpatient Length of stay trends

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 63

Code Most Responsible Diagnosis Discharges Total Days ALOSK35 Acute Appendicitis 339 908 2.7J21 Acute Bronchiolitis 309 1479 4.8Z51 Other Medical Care 296 1200 4.1J35 Chronic Diseases Of Tonsils And Adenoids 248 253 1.0G40 Epilepsy 211 932 4.4J45 Asthma 208 545 2.6F32 Depressive Episode 190 2066 10.9Z54 Convalescence 177 535 3.0J18 Pneumonia, Organism Unspecified 149 582 3.9S42 Fracture Of Shoulder And Upper Arm 138 175 1.3R10 Abdominal And Pelvic Pain 131 227 1.7E10 Type 1 Diabetes Mellitus 106 277 2.6G47 Other Sleep Disorders 98 106 1.1T81 Complications Of Procedures, Not Elsewhere Classified 89 400 4.5F43 Reaction To Severe Stress, And Adjustment Disorders 87 595 6.8S82 Fracture Of Lower Leg, Including Ankle 74 137 1.9R56 Convulsions, Not Elsewhere Classified 71 181 2.5Z53 Persons Encountering Health Services For Specific Procedures, Not Carried Out 71 74 1.0F90 Hyperkinetic Disorders 69 960 13.9S52 Fracture Of Forearm 66 89 1.3A09 Other Gastroenteritis And Colitis Of Infectious And Unspecified Origin 62 145 2.3D70 Agranulocytosis 61 311 5.1K56 Paralytic Ileus And Intestinal Obstruction Without Hernia 59 453 7.7N39 Other Disorders Of Urinary System 57 335 5.9A08 Viral And Other Specified Intestinal Infections 56 215 3.8M41 Scoliosis 54 329 6.1S72 Fracture Of Femur 54 126 2.3R50 Fever Of Other And Unknown Origin 52 181 3.5Q54 Hypospadias 51 78 1.5T18 Foreign Body In Alimentary Tract 50 78 1.6S06 Intracranial Injury 50 237 4.7J05 Acute Obstructive Laryngitis [Croup] And Epiglottitis 49 119 2.4E84 Cystic Fibrosis 49 744 15.2A41 Other Sepsis 49 420 8.6R62 Lack Of Expected Normal Physiological Development 47 457 9.7J06 Acute Upper Respiratory Infections Of Multiple And Unspecified Sites 46 170 3.7

Top 50% Diagnoses 3973 16119 4.1

acH inpatient

most responsible

Diagnoses

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Department of paeDiatrics | annual report 201364

pLc inpatient most responsible Diagnoses - top 10 Diagnoses

Code Most Responsible Diagnosis Discharges Total Days ALOS

P59 Neonatal Jaundice From Other And Unspecified Causes 277 326 1.2

J21 Acute Bronchiolitis 160 478 3.0

P07 Disorders Related To Short Gestation And Low Birth Weight, NEC 95 1862 19.6

J18 Pneumonia, Organism Unspecified 88 211 2.4

Top 10 Diagnoses 620 2877 4.6

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ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 65

Code Most Responsible Diagnosis Discharges Total Days ALOS

P59 Neonatal Jaundice From Other And Unspecifi ed Causes 277 326 1.2

J21 Acute Bronchiolitis 160 478 3.0

P07 Disorders Related To Short Gestation And Low Birth Weight, NEC 95 1862 19.6

J18 Pneumonia, Organism Unspecifi ed 88 211 2.4

Top 10 Diagnoses 620 2877 4.6

Unit ACH PLC

Fiscal Year Unit 1 Unit 2 24HR Unit 3 Unit 4 MHINPAT NICU PICU Total Unit 31

200809 86.0% 93.6% 72.8% 92.7% 89.5% 86.5% 65.8% 89.5% 73.9%

200910 71.4% 93.7% 61.5% 91.8% 89.4% 94.9% 59.1% 87.1% 73.1%

201011 73.8% 94.1% 57.1% 92.7% 91.8% 89.1% 62.1% 84.0% 72.4%

201112 83.5% 94.2% 63.8% 96.1% 94.7% 92.9% 84.7% 67.3% 88.1% 75.5%

201213 85.2% 93.7% 69.7% 95.8% 92.4% 95.6% 82.4% 75.5% 90.0% 74.0%

85.2%  

93.7%  

69.7%  

95.8%  

92.4%  

95.6%  

82.4%  

75.5%  

0.0%   20.0%   40.0%   60.0%   80.0%   100.0%   120.0%  

Unit  1  

Unit  2  

24HR  

Unit  3  

Unit  4  

MHINPAT  

NICU  

PICU  

ACH  Unit  Occupancy  Fiscal  2012/13  

annual paediatric Unit occupancy at acH and pLc (excluding nicUs)

Page 68: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201366

acH picU activity

Fiscal Yr 08/09 09/10 10/11 11/12 12/13

PICU Cases 791 733 780 760 855

Admissions to PICU* 493 465 445 397 435

Transfers Into PICU from Units* 249 235 248 279 294

Transfers Into PICU from ADOP/PACU* 125 138 161 150 156

Discharge from PICU 198 161 150 115 119

Transfers Out of PICU to Units* 609 580 643 664 715

PICU Unit LOS 3326 2856 3831 3038 3771

Hospital LOS - PICU Cases 11,681 11,088 12,989 11,554 13,423

Extra-Corporal Life Support cases* n/a 1 0 4 9

* fi scal year based on hospital admission date, others based on hospital discharge date.Patients may have more than 1 admission, transfer into PICU, and transfers out of PICU on a hospital stayExtra-Corporal Life Support cases* are collected if the the following CIHI criteria are met, effective Apr 2012:- performance in an operati ng/interventi on room (e.g. endoscopy room, cardiac catheterizati on room) or;- performance in the presence of an anestheti st (i.e. anestheti c record on the chart) or;- performance using the following approaches: open, endoscopic, percutaneous transluminal/transarterial or."

791 733

780 760 855

0 100 200 300 400 500 600 700 800 900

1000

08/09 09/10 10/11 11/12 12/13

Cas

es

ACH PICU Cases

Page 69: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 67

NICu Indicators aCH FMC PlC* rgH Total

11/12 12/13 08/09 09/10 10/11 11/12 12/13 08/09 09/10 10/11 11/12 12/13 08/09 09/10 10/11 11/12 12/13 08/09 09/10 10/11 11/12 12/13

Discharges 86 122 1091 1184 1175 1132 1173 782 790 798 809 778 990 1007 1010 1000 1046 2863 2981 2983 3027 3119

Total Days Stay 2317 3913 11573 13356 13678 12789 12620 8833 9209 9505 10009 9736 10349 10814 11047 10306 10306 30755 33379 34230 35421 36575

Average Length of Stay (ALOS) 26.9 32.1 10.6 11.3 11.6 11.3 10.8 11.3 11.7 11.9 12.4 12.5 10.5 10.7 10.9 10.3 9.9 10.7 11.2 11.5 11.7 11.7

Intracity Transfer 21 27 529 586 647 689 671 53 62 53 45 53 80 64 50 53 58 662 712 750 808 809

Total Days in NICU Unit 1442 2365 10750 12427 13369 11889 11780 7639 8099 8525 8738 8760 9740 10150 10679 9562 9494 28129 30676 32573 31631 32399

Average Case Weight (ARIW) 9.82 10.59 3.43 3.62 3.66 3.41 3.39 2.22 2.28 2.30 2.36 2.32 2.08 2.03 2.13 2.02 1.91 2.63 2.73 2.78 2.86 2.91

Unique Patients 2300 2358 2360 2315 2390

Average Neonatal Length of Stay per Patient (Days)

13.4 14.2 14.5 15.3 15.3

nicU activity at all Hospitals

Page 70: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201368 DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 2013

CANADIAN NEONATAL NETWORK

We have the highest number of admissions amongst 30 sites and we have the 3rd highest acuity scores (SNAPPE II). With adjustment, our standardized mortality is 1.4% (3.3% mean), our standardized morbidity rate is 33.9% (32.8% mean). Using adjusted odds ratios we are at the mean for ROP, to the left of centre for other outcomes, except for BPD (AOR 1.8) and IVH with an AOR of 1.2. We are reviewing all the cases of IVH from 2012, however in a preliminary review of the first 6 months of 2013, it looks like the IVH rates are coming back to our previous baseline. Our AOR for BPD is 1.8, we are no longer the site at the extreme right. Overall, we are at 21.8% compared to the CNN mean of 15.4%.

¢ Inborn

¢ Outborn

¢ Readmission

admissions to canadian neonatal network participating centers

Number of admissions

CN

N S

ite

s

²D

ata

co

lle

cte

d o

n s

ele

cte

d c

oh

ort

of

elig

ible

ad

mis

sio

ns

on

ly.

Foothills Medical Centre (#30) with highest number of admission among centre in Canadian Neonatal Network (CNN) 2012

Excerpts from Canadian Neonatal Network (CNN) Annual Report 2012

Data collected on selected cohort of eligible admissions only.

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 69ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 69

¢ SNAPPEII Score

¢ SNAPII Score

admissions illness severity scores (snap-ii and snap-iipe) by site

(only for sites that contributed data on all eligible admissions)(n=25 sites, 14 247 admissions, 363 missing data on SNAPP score)

Sit

e

Mean Scores

0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18

A

C

E

F

G

H

I

j

K

L

M

N

O

P

Q

S

T

U

W

X

y

Z

AA

AB

AD

Foothills Medical Centre (site X) with 3rd highest severity

of illness scores among centres in

CNN 2012

snap-iipe sandardized site mortality rates

¢ Crude mortality rate

¢ SNAPIIPE standarized

mortality rate

Sit

e

Per 100 admitted infants0 1 2 3 4 5 6 7 8 9 10

A

B

C

D

E

F

G

H

I

j

K

L

M

N

O

P

Q

R

S

T

U

V

W

X

y

Z

AA

AB

AC

AD

Foothills Medical Centre (site X),

comparison of crude and

adjusted mortality in CNN 2012

‡ Site R has a crude mortality rate of 18.9% and site AC has a crude mortality rate of 17.5%, but they are not shown completely in the graph. Please refer to table

on page 42 for actual persentages for sites R and AC.

Page 72: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201370

Necrotizing enterocolitis ≥ stage 2) among neonates with ga, 33 weeks among centres in CNN 2012

Oxygen use at 36 weeks post-menstrual age in neonates with ga, 33 weeks at birth in CNN 2012

Number of neonates: 3 846

Reference site: M

Inclusion criteria: GA<33 weeks Age at admission less than 4 days

Significant predictors identified by multivariate analysis and adjusted for: GA Maternal diabetes

*Sites significantly different from reference site (P<0.05)

Number of neonates: 3 742

Reference site: Q

Inclusion criteria: GA<33 weeks Age at admission less than 4 days Survival to 36 week post-menstrual age or discharee

Significant predictors identified by multivariate analysis and adjusted for: GA Male Apgar at 5 minutes SNAP-II Score SGA (BW <10* percentile for GA)

*Sites significantly different from reference site (P<0.05)

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 71

retinopathy of prematurity stage 3 and higher among centres in CNN 2012

Number of neonates: 1 562

Reference site: X

Inclusion criteria: GA<33 weeks Screende for ROP Age at admission less than 4 days

Site Z was not included in thes analysis due to the small number of neonate who meet the includion criteria

Significant predictors identified by multivariate analysis and adjusted for: GA SGA(BW<10* centile for GA)

*Sites significantly different from reference site (P<0.05)

Outcome is attributed to the network site of first admission

Page 74: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201372 DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201372

acH eD tier 1 measures - fisical 2012/13

Child Health Annual Report 2012/13

ACH Emergency Department Visits

Fiscal Yr 08/09 09/10 10/11 11/12 12/13ED Visits 55,954 59,170 59,639 65,016 72,719

ACH ED Tier 1 Measures - Fiscal 2012/13:

55,95459,170 59,639

65,016

72,719

40,000

45,000

50,000

55,000

60,000

65,000

70,000

75,000

80,000

08/09 09/10 10/11 11/12 12/13

Visi

ts

ACH Emergency Department Visits

# Met TargetED Visits

(Den) % Met Target Avg Time Median TimeAdmitted (target: within 8 hours) 3128 4839 64.6% 8.5 hours 6.5 hours

64699 65695 98.5% 2.8 hours 2.3 hoursTriage to Physician for CTAS 2 patients (target: 30 minutes) 4264 7038 60.6% 33 min. 25 min.Triage to Physician for CTAS 3 patients (target: 60 minutes) 12930 32452 39.8% 90 min. 74 min.

2059 4587 44.9% 218 min. 99 min.1445 4838 29.9% 58 min. 45 min.

Tier 1 Measures

Discharged (target: within 4 hours)

Admission Request to Admission (target: 90 minutes)Bed Allocation to ED Departure (target: 30 minutes)

UQIAnnual_F1213_10439.xlsx Page 67

80,000

75,000

70,000

65,000

60,000

55,000

50,000

45,000

40,00008

/09

09/1

0

10/1

1

11/12

12/1

3

ED

Vis

its

acH emergency Department Visits

55.95459,170 59,639

65,016

72,719

Child Health Annual Report 2012/13

ACH Emergency Department Visits

Fiscal Yr 08/09 09/10 10/11 11/12 12/13ED Visits 55,954 59,170 59,639 65,016 72,719

ACH ED Tier 1 Measures - Fiscal 2012/13:

55,95459,170 59,639

65,016

72,719

40,000

45,000

50,000

55,000

60,000

65,000

70,000

75,000

80,000

08/09 09/10 10/11 11/12 12/13

Visi

ts

ACH Emergency Department Visits

# Met TargetED Visits

(Den) % Met Target Avg Time Median TimeAdmitted (target: within 8 hours) 3128 4839 64.6% 8.5 hours 6.5 hours

64699 65695 98.5% 2.8 hours 2.3 hoursTriage to Physician for CTAS 2 patients (target: 30 minutes) 4264 7038 60.6% 33 min. 25 min.Triage to Physician for CTAS 3 patients (target: 60 minutes) 12930 32452 39.8% 90 min. 74 min.

2059 4587 44.9% 218 min. 99 min.1445 4838 29.9% 58 min. 45 min.

Tier 1 Measures

Discharged (target: within 4 hours)

Admission Request to Admission (target: 90 minutes)Bed Allocation to ED Departure (target: 30 minutes)

UQIAnnual_F1213_10439.xlsx Page 67

acH emergency Demartment Visits

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ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 73ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 73

Child Health Annual Report 2012/13

ACH ED Visits by CTAS ScoreCTAS Triage Level ED Visits % Total1 - Resusc 349 0.5%2 - Emergent 7548 10.4%3 - Urgent 34574 47.5%4 - Semi-Urgent 28556 39.3%5 - Non-Urgent 1673 2.3%9 - Unknown 19 0.0%Total 72719 100.0%

1%

10%

39%

2% 0%

ED Visits by CTAS Score

1 ‐ Resusc

2 ‐ Emergent

3 ‐ Urgent

4 ‐ Semi‐Urgent

48%

5 ‐ Non‐Urgent

9 ‐ Unknown

UQIAnnual_F1213_10439.xlsxPage 71

acH emergency Demartment Visits by ctas score

acH eD Visits by ctas score

Resusc   Emergent   Urgent   Semi-­‐Urgent   Non-­‐Urgent   Unknown  

48%

39%

10%

0%1%2%

Resusc

Emergent

Urgent

Semi-Urgent

Non-Urgent

Unknown

Page 76: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201374

acH paediatric ambulatory care Visits

ACH Paediatric Ambulatory Care Visits All Visits Unique Patients

# Program Supported Description F1213 F1213

218 (Ach) Youth Health Program Adolescents 577 173

994 Aboriginal Liaison 0 0

178 Acets Program 884 178

92 Ambulatory Services On Tcluster 0 0

22 Asthma Clinic 6277 1553

933 Bereavement And Palliative Care 551 163

126 Brain Injury 671 277

29 Cardiology Clinic 6881 4323

29 Cardiology Clinic (by program_no) 2823 2286

103 Child Abuse Program (Ach) 1985 401

138 Cope Program 202 44

34 Cystic Fibrosis Clinic 3778 156

12 Diabetes Clinic (Ach) 8236 974

139 Eating Disorders Program 22936 374

23 Endocrinology Clinic 3685 1064

171 Fetal Alcohol Syndrome 178 77

4 Gastroenterology 12896 2809

4 Gastroenterology (by program_no) 118 112

110 Genetics 3571 2804

117 Hematology Clinic 1373 461

25 Hemophilia Clinic 269 86

58 Infectious Disease Clinic 299 235

99 Medical Day Treatment (Ach) 0 0

190 Metabolic Disease Clinic Ach 2289 472

41 Nephrology Clinic 10156 4672

821 Neuro Oncology Clinic 427 60

18 Neurology Clinic 6642 2412

54 Neuromotor Clinic 4506 716

49 Neuromuscular Clinic 1148 185

31 Oncology 9611 677

939 Parenteral Therapy Program 205 127

156 Pediatric Centre For Weight And Health (Ach) 1093 163

14 Pediatric Neuro Developmental Clinic 2974 1207

818 Pediatric Sleep Lab 1895 844

134 Peds Behavioral And Development Clinic 0 0

19 Perinatal Clinic 4547 772

33 Pulmonary Clinic 1634 560

204 Renal Ach Hemodialysis 1 1

204 Renal Ach Hemodialysis (by program_no) 416 4

56 Respiratory Home Care 4339 526

80 Respiratory Services 2610 901

27 Rheumatology Clinic 1028 351

Total 133711 52666

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 75

Page 78: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201376

Page 79: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 77

Education and Training Programs

ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS

OVERVIEW

Education at all levels is a fundamental priority for the Department of Paediatrics and all members are expected to participate in direct teaching and/or education leadership throughout the Department, within the Faculty of Medicine, AHS and in the broader community. The Department of Paediatrics is very proud of the accomplishments of its members in paediatric education. Many educational innovations are occurring and being recognized locally as well as nationally and internationally.

Paediatric undergraduate medical education is woven throughout the three years of the University of Calgary medical school curriculum, with a combination of didactic and clinical teaching. Post Graduate Medical Education is delivered primarily through the General Paediatrics Residency Training Program, as well as through eleven other Royal College affiliated Residency Training Programs. All programs received full Royal College accreditation at the last RCPSC external review in 2009.

Continuing Medical Education is a vital part of paediatric education and contributes to paediatric learning not only within Calgary, but also to physicians via telehealth throughout southern Alberta and south-eastern British Columbia.

Some faculty members participate in undergraduate education though the O’Brien Bachelor of Health Science program at the University of Calgary. Numerous faculty members participate as supervisors and committee members for MSc, PhD and post-doctoral programs throughout the Faculty of Medicine.

In recent years, Paediatric Simulation education has been especially important in providing hands-on learning to all levels of learners as well as practicing health care professionals. A new simulation centre is opening january 8th 2014 at ACH (KidSIM, Pediatric Patient Simulation Program) to further assist in this area of paediatric education. ���

overview

Undergraduate medical education (Ume)

post Graduate medical education (pGme)

continuing medical education (cme)

Page 80: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201378

Undergraduate Medical Education (UME)

Paediatrics is taught throughout years 1 and 2 of the University of Calgary medical school curriculum (which is three years in duration). The largest amount of paediatric teaching occurs in the Women’s and Child Health course. This course, co-chaired by Dr. Marielena DiBartolo, introduced paediatric clinical skill training for all students since 2012. This Course allows students early exposure to paediatric clinical skills for patients of all ages.

In year 3, the clerkship year, students rotate through different rotations and spend six weeks learning paediatrics. Our curriculum, based on the national undergraduate paediatrics curriculum, is highly regarded by most students. Most students will complete a three-week rotation in general paediatrics in one of the three locations:

• Outreach sites in Lethbridge, Medicine Hat, or Red Deer (inpatients, outpatients, emergency department, neonatology)

• Peter Lougheed Hospital (inpatients, outpatients, emergency department, neonatology)

• Alberta Children’s Hospital (inpatients)

UME Director and Clerkship Director: dr. Susan bannister

UME Deputy Director and Clerkship Deputy Director: dr. Julian Midgley

Clerkship Evaluation Coordinator: dr. Nicole Johnson

The other three weeks will be a combination of (usually) two of the following:

• Community Paediatrics

• ACH Emergency Department

• Neonatology

• ACH subspecialties

• The ACH subspecialties available are

Cardiology

Developmental / Adolescent Medicine

Endocrinology

Gastroenterology

Infectious Disease

Nephrology

Neurology

Oncology

Respiratory

Rheumatology

���

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 79

post Graduate Medical Education

PGME PROGRAMS AND TRAINEES

There are three paediatric-affiliated PGME programs that being in the PGy1 year:

• General Paediatrics

• Paediatric Neurology

• Medical Genetics

(Note that Medical Genetics is a Section of the AHS Department of Paediatrics but is a Department in the Faculty of Medicine.)

In addition, there are nine subspecialty paediatric programs that start at the PGy4 level or later:

• Developmental Paediatrics

• Emergency Medicine

• Endocrinology and Metabolism

• Gastroenterology

• Hematology/Oncology

• Infectious Diseases

• Neonatology/Perinatology

• Nephrology

• Respiratory Medicine

���

201

2-13

2011-

12

20

10-11

89trainees

93trainees

117trainees

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Department of paeDiatrics | annual report 201380

GeneraL paeDiatrics

Program Co-Directors: Dr. Deborah Fruitman & Dr. Kathy Tobler

Like all paediatric training programs in Canada, ours is of four years duration. The first three years cover core training in general paediatrics. The first year provides a breadth of exposure to general paediatrics.

The second year facilitates career options by exposing residents to subspecialties in greater depth.

The third year is designed to consolidate the education acquired in core rotations and to provide opportunities for more elective rotations to deepen knowledge and experience in selected areas.

The final year is flexible, with residents able to pursue subspecialty training, or spend more time training as a community or hospital based general paediatrician.

trainees: 2012/2013: 45

meDicaL Genetics

Program Director: Dr. Mary Ann Thomas

The first two years of the program involve training in paediatrics, internal medicine, high risk obstetrics, and crisis counselling, with on-going communication with the Medical Genetics program director. The third year of the program is devoted to clinical metabolic service and laboratory experience with rotations in cytogenetics, molecular genetics and biochemical genetics. It is possible to begin some clinical genetics rotations in the third year and participation in genetics outreach clinics and resident clinic starts in this year.

Attendance at clinical genetic reviews and weekly genetics seminars is recommended. A core month of genetics occurs each year for all residents (R1-R5).

The clinical component during the 4th and 5th years of training is based at the Alberta Children's Hospital. There is an active consulting service in clinical genetics for both in-patients and out-patients through the Alberta Children's Hospital. In addition, there is an extensive outreach program with clinics in Lethbridge, Medicine Hat, and Red Deer.

trainees: 2013/2014: 5

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 81

neUroLoGY

Program Director: Dr. Michael Esser

The Paediatric Neurology Program at the University of Calgary is education driven.

During the first year of the program, Residents attend the weekly Paediatric Grand Rounds, and participate in other General Paediatric teaching rounds and Paediatric academic half day seminars one half day per week. During the first year, the Residents also take part in a 4-week Research Methods Course, which enables them to prepare a clinical or basic science research project to be completed within the next two to three years of their training.

Most of the 5-year Paediatric Neurology Residency Training Program is spent at the Alberta Children's Hospital with the exception of the rotations in Neonatal Intensive Care, which take place at the Foothills Medical Centre, and rotations in Adult Neurology, which occur at the Foothills Medical Centre, the Peter Lougheed Centre, the Rockyview General Hospital, and the newly constructed South Health Campus Hospital in Calgary.

trainees: 2012/2013: 9

DeVeLopmentaL paeDiatrics

Program Director: Dr. Ben Gibbard

The University of Calgary offers a two-year training program in Developmental Paediatrics accredited by the Royal College of Physicians and Surgeons of Canada. The program is designed for 1-2 residents per year. The training program's goal is the development of trainees with excellent clinical skills in an atmosphere of academic inquiry.

trainees:2012/2013: 1

Page 84: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201382

emerGencY meDicine

Program Director: Dr. Izabela Sztukowski

The Paediatric Emergency Medicine Program is of two years duration. In the first year, there is an emphasis on significant exposure to the paediatric emergency department experience, as well as exposure to critical care and anaesthesia subspecialties for residents coming from both the Paediatric and Emergency Medicine tracks. Additional training ensures exposure to surgical and emergency subspecialties or paediatric subspecialties, depending on where the resident's core training was. There is also an emphasis on the initiation of research and this is carried through in both first and second years with dedicated blocks. The second year of fellowship continues to provide varied clinical experiences, as well as exposure to administrative and leadership responsibilities.

In the junior year of fellowship, the resident would participate in the Paediatric or Emergency Medicine preparation program for the Royal College examination, i.e., OSCE, written examination, oral examination, and observation of clinical skills, to help ensure successful outcome in the core specialty.

trainees: 2012/2013: 7

enDocrinoLoGY anD metaBoLism

Program Director: Dr. Jonathan Dawrant

The Residency Program in Paediatric Endocrinology and Metabolism was established in November 2002. It is a two-year subspecialty post-graduate program located at the Alberta Children’s Hospital and University of Calgary Faculty of Medicine. Residents receive clinical and academic training in the principles of endocrine and metabolic disease as they apply to children and adolescents and acquire the knowledge and skills necessary to fulfill the essential roles and key competencies of an Endocrinologist as defined by the Royal College of Physicians and Surgeons of Canada. Usually only one or two Residents are enrolled in the program per year and accordingly, individualized teaching and training is provided by our faculty. Upon completion of the program, trainees are equipped to function as consultants in Paediatric Endocrinology either in an independent private practice or in an academic teaching or research program within a university setting.

trainees: 2011/2012: 2

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 83

GastroenteroLoGY

Program Director: Dr. Leanna McKenzie

The Section of Paediatric Gastroenterology and Nutrition offers two types of subspecialty residency training:

• A two-year fellowship for trainees wishing to develop clinical skills in paediatric clinical gastroenterology and nutrition; and

• A three-year fellowship combined with Master’s degree or research project for those interested in pursuing a career in academic paediatric gastroenterology and nutrition.

The first year of training is primarily clinical, and residents spend approximately half the year on clinical inpatient service performing supervised consultations at the inpatient units and emergency department of Alberta Children’s Hospital. When not performing inpatient service, trainees participate in outpatient clinics, endoscopy, research, electives and education sessions.

The second and third years are similar to the first, but with less inpatient service. Clinical electives are encouraged, and residents are encouraged to arrange electives in nutrition, hepatology (within Canada or international), and pathology. Electives in motility, metabolics, radiology,

and research may also be arranged. Trainees pursuing an academic career with a three year residency may enter a basic or clinical science research fellowship, or may pursue a Master’s degree in Clinical Epidemiology, Public Health or Medical Education, with a focus on Gastroenterology.

Education time is protected, and residents participate and contribute to the weekly paediatric gastroenterology academic half-day as well as other scheduled teaching sessions. Residents are expected to submit a small research project in their first year, and develop a more substantial research project during their second and third year (if applicable).

The ten faculty members at Alberta Children’s Hospital demonstrate a commitment to education and have a wide variety of clinical and research interests including Mucosal Immunology, Inflammatory Bowel Disease, Celiac disease, Hepatology, Intestinal Failure, Cystic Fibrosis, Medical Education and Motility.

trainees: 2012/2013: 4

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84 DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 2013

infectioUs Diseases

Program Director: Dr. Rupesh Chawla

Training incorporates the principle of increasing responsibility. It includes one year of clinical residency in the entire spectrum of acute, chronic and recurrent infectious diseases in hospitalized and ambulatory patients, with opportunities to participate in epidemiologic studies of infections in the hospital and community. Two months of the one-year experience is spent in adult infectious diseases.

Trainees will receive six months of full time laboratory residency in medical microbiology including virology, bacteriology, mycology and parasitology. At least one of these six months is committed to virology. One month is spent in Infection Prevention and Control. Five months of approved residency in infectious diseases, or microbiology, or in research is offered, relevant to the goals of the trainee, the objectives of infectious diseases, and acceptable to the program director. Elective experiences outside of Calgary are possible.

The Infectious Diseases clinical service at Alberta Children’s Hospital consists of daily ambulatory clinics and inpatient consultations. The program includes academic rounds with the paediatric infectious disease group as well as city-wide combined adult and paediatric infectious diseases. An academic half-day is organized for ID trainees in both the paediatric and adult programs with a two year cycle of seminar topics.

trainees: 2012/2013: 2

neonatoLoGY

Program Director: Dr. Majeeda Kamaluddeen

Neonatal/Perinatal Medicine residency program is a two-year program with an optional third year for research. The curriculum includes a minimum of 12 months of clinical rotation. Six months of this is at the Level 3 NICU at Foothills Medical Centre, a tertiary care centre with high risk obstetric and perinatology services and, three months is at the Alberta Children’s Hospital NICU which provides care for surgical, cardiac and complex care neonates. Rotations in Level 2 nursery and paediatric critical care may be counted towards these 12 months. Participation in research is strongly recommended with time and mentorship allocated for research activity. Research pursuits of the mentors encompass clinical, epidemiological and medical education. Other academic activities include rotations in Maternal-Fetal Medicine, Perinatal follow-up clinic and, participation in academic half-day sessions, clinical rounds, grand rounds and journal club etc.

trainees: 2012/2013: 12

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 85

paeDiatric nepHroLoGY

Program Director: Dr. Lorraine Hamiwka

The University of Calgary offers a two to three-year training program in Paediatric nephrology approved by the Royal College of Physicians and Surgeons of Canada. The program is designed for 1-2 trainees per year.

During the first clinical year, the trainee will perform supervised inpatient, outpatient, and emergency department clinical consultations at the Alberta Children's Hospital. The trainee will develop skills in all aspects of chronic and acute care in paediatric nephrology including the management of general nephrology, chronic kidney disease, dialysis and transplant patients. Trainees participate in and contribute to the nephrology academic half day, literature reviews/journal clubs, and nephrology teaching rounds. The development of a research proposal will be initiated in the first year, the majority of which will be carried out during the second and/or third year of training. Three blocks are available for either research or elective time during the first year of training.

During the second and third year, trainees continue to attend outpatient clinics and perform call duties. Up to eight months of research or elective rotations are available. Trainees intending to focus on a clinical paediatric nephrology residency will continue to enhance their clinical experience but at a more advanced and specialized level.

Trainees pursuing an academic career may complete basic or clinical science research training including entering into a graduate program (M.Sc. or Ph.D) or a medical education fellowship, all with an emphasis on paediatric nephrology.

trainees: 2012/2013: 3

respiratorY meDicine

Program Director: Dr. Marielena DiBartolo

We have a 2-year, RCPSC-accredited subspecialty residency program, which can be extended towards a research career or further clinical training if desired. There is space for 2 fellows per program year. Most of the core Pediatric Respiratory Medicine clinical work is accomplished in the first year, although there is an expectation that the primary research project will be developed and initiated during this time as well. The main focus of the second year of training is broadening of expertise through clinical electives, and completion of the scholarly project. There are components of the program that can be tailored to each individual interest.

Rotations are on a 4 weekly basis (13/year). One month in Adult Respirology and 2 months in intensive care (PICU and/or NICU) are mandatory. Electives are chosen from disciplines relevant to Respiratory Medicine including Radiology, Otolaryngology, Infectious Disease, and Allergy/immunology. These months are planned according to the objectives of the fellow in conjunction with the respiratory residency training director and in collaboration with other associated programs.

trainees: 2012/2013: 3

Page 88: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201386

continuing Medical Education (CME)

The Department conducts weekly Paediatric Grand Rounds from September to june of each academic year. These rounds are held in the Auditorium at ACH but are also broadcast via telehealth to other hospitals and offices throughout Calgary, Alberta and south-eastern British Columbia. The audience comes from all the disciplines involved in the care of children.

Throughout the year, several special named rounds are held including the Dr. Donald Clogg Lecture in Paediatric Emergency Medicine and the Dr. Sam Darwish Lecture in Paediatric Neurology. Of the 40 Grand Rounds in 2013 speakers from outside ACH, including 8 from various cities in the US, presented on 15 occasions.

Most sections conduct regular continuing education rounds, often in conjunction with adult specialty colleagues. These include evening rounds organized by Community Paediatricians often with speakers from ACH paediatric subspecialty sections.

Director: dr. Julian Midgely

The Department of Paediatrics contributes to various Faculty of Medicine CME courses including the Practical Pediatrics Course (held in june), the Evening Course Program for family physicians and the Calgary Therapeutics Course.

In February 2013, the 22nd International Paediatric Infectious Diseases Course was held in Banff. Dr. Taj jadavji founded and still directs this longstanding and successful course. In March 2012, the second “PEACH” (Pediatrics Emergencies ACH) conference was held at ACH. Dr. Angelo Mikrogianakis is the director of this exciting new course. In May 2013 the first “Paediatric Update Conference” for family physicians, paediatricians and other paediatric health care workers was held with good attendance and excellent reviews.

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 87

HUman simULation eDUcation

Program Director: Dr. Vincent Grant

An internationally-recognized simulation-based education program is located at the ACH, with medical leadership through the Department of Paediatrics. The ACH KidSIM™ Program (www.kidsim.ca) provides hands-on learning in paediatric acute care to undergraduate and postgraduate learners, as well as to practicing healthcare professionals, with a focus on team training, interprofessional education and patient safety. Novel programs include a Family Centred Care initiative to use simulation to teach families via simulation, a mobile outreach program that provides interprofessional education to the rural and regional centres in Southern Alberta and South-eastern British Columbia, and a just-in-time Education Program aimed at preparing care providers in real time for patients most likely to deteriorate during their care, among many others. The KidSIM™ Program has also developed a reputation for high quality faculty development through its’ leadership of the nationally-recognized WISE (Workshops In Simulation Education) curriculum and invitations to present faculty development workshops at both national and international meetings.

The KidSIM™-ASPIRE (Assessing Simulation in Paediatrics:

Improving Resuscitation Education) Paediatric Research Program has become an emerging international leader in simulation-based research, with a significant number of competitive grants, publications, and abstracts accepted at national and international conferences. KidSIM™ Faculty Members are also in significant leadership roles in the Faculty of Medicine at the University of Calgary, the eSIM Provincial Simulation Program, the Canadian Paediatric Simulation Network, the Canadian Network for Simulation in Healthcare, the Society for Simulation in Healthcare and the International Paediatric Simulation Society.

The program, currently in its’ 9th year of existence, held approximately 400 sessions (60% of which were interprofessional in nature) and taught 3,500 learners in 2012/13, adding up to almost 1,000 hours of simulation-based education. A total of 85 educators provide training using simulators from neonatal to adolescent mannequins. A new $2.4 million dollar simulation suite is officially opening in january 2014.

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Page 90: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201388

PATIENT NUMBER OF ORIGINS PATIENTSAirdrie ......................................................................2,699Banff ............................................................................. 121Bragg Creek ................................................................ 107Brooks ......................................................................... 295Calgary................................................................... 63,332Canmore ..................................................................... 296Carstairs ...................................................................... 200Chestermere .............................................................. 940Cochrane .................................................................1,164Drumheller ................................................................. 176Edmonton ................................................................... 151Fort McMurray............................................................. 63Grande Prairie ............................................................. 45High River ................................................................... 453Innisfail ......................................................................... 121Irricana ........................................................................... 68Lethbridge ................................................................... 742Medicine Hat .............................................................. 626Morley .......................................................................... 339Nanton .......................................................................... 98Okotoks ...................................................................1,258Olds .............................................................................. 239Red Deer .................................................................... 612Rocky Mountain House ...........................................120Siksika .......................................................................... 155Strathmore ................................................................. 699Sundre .......................................................................... 119Other Alberta Locations ......................................5,566ALBERTA TOTAL 80,804

British Columbia ........................................................732Saskatchewan ............................................................. 374Manitoba ....................................................................... 16Ontario .......................................................................... 20Quebec .............................................................................5Atlantic Canada ..............................................................8Canadian Territories ................................................... 26TOTAL OTHER PROVINCES& TERRITORIES 1,181

OUTSIDE CANADA 35 *OVERALL PATIENT TOTAL 82,020

*represents the number of individual patients who visited the Alberta Children’s Hospital in 2011-2012

Children who relyon care from the

Alberta Children’s Hospital

PATIE

NT

NUM

BER O

F

ORIG

INS

PATIE

NTS

Airdrie

.......

........

........

........

........

........

........

........

.......2

,699

Banff

.......

........

........

........

........

........

........

........

........

......1

21

Brag

g Cre

ek ....

........

........

........

........

........

........

........

....10

7

Broo

ks ...

........

........

........

........

........

........

........

........

......2

95

Calgar

y......

........

........

........

........

........

........

........

.....6

3,332

Canmor

e .....

........

........

........

........

........

........

........

........

296

Carsta

irs ....

........

........

........

........

........

........

........

........

..200

Cheste

rmer

e ......

........

........

........

........

........

........

........

940

Cochr

ane .

........

........

........

........

........

........

........

........

1,164

Drumhe

ller ..

........

........

........

........

........

........

........

.......1

76

Edmon

ton .

........

........

........

........

........

........

........

........

..151

Fort

McMur

ray....

........

........

........

........

........

........

........

.63

Grand

e Pra

irie .

........

........

........

........

........

........

........

....45

High R

iver ..

........

........

........

........

........

........

........

........

.453

Innisf

ail ....

........

........

........

........

........

........

........

........

.....1

21

Irrica

na ....

........

........

........

........

........

........

........

........

.......

68

Leth

bridg

e ......

........

........

........

........

........

........

........

.....7

42

Medici

ne H

at ....

........

........

........

........

........

........

........

..626

Morley

........

........

........

........

........

........

........

........

........

..339

Nanto

n .....

........

........

........

........

........

........

........

........

.....9

8

Oko

toks

.......

........

........

........

........

........

........

........

....1,2

58

Olds

........

........

........

........

........

........

........

........

........

......2

39

Red D

eer .

........

........

........

........

........

........

........

........

...612

Rock

y Mou

ntain

Hou

se ....

........

........

........

........

.......1

20

Siksik

a .....

........

........

........

........

........

........

........

........

.....1

55

Strath

more .

........

........

........

........

........

........

........

........

699

Sund

re ....

........

........

........

........

........

........

........

........

......1

19

Oth

er A

lberta

Loca

tions

.......

........

........

........

.......5

,566

ALBER

TA TOTA

L

80,80

4

Britis

h Colu

mbia ....

........

........

........

........

........

........

....73

2

Sask

atche

wan ...

........

........

........

........

........

........

........

..374

Manito

ba ...

........

........

........

........

........

........

........

........

....16

Ont

ario

........

........

........

........

........

........

........

........

........

..20

Que

bec ..

........

........

........

........

........

........

........

........

........

...5

Atlant

ic Can

ada .

........

........

........

........

........

........

........

.....8

Canad

ian Te

rrito

ries ..

........

........

........

........

........

........

.26

TOTAL

OTHER P

ROVINCES

& TER

RITO

RIES

1,181

OUTSI

DE CAN

ADA

35

*O

VERALL

PATIE

NT TOTA

L

82,02

0

*repre

sents

the nu

mber o

f indiv

idual

patie

nts w

ho vi

sited

the

Albert

a Chil

dren’s

Hos

pital

in 20

11-20

12

Childre

n who re

ly

on care

from

the

Alberta

Child

ren’s

Hospita

l

Page 91: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 89

Mentorship Program

A committee was struck in 2011 to design a mentorship program, and it was launched in Fall 2012 with its first intake of participants. The mentorship begins with coaching mentee participants to define a project that they are passionate about, is part of their usual job activities in one of the clinical, education, service or research domains, is achievable within the program time-frame and will result in a defined scholarly output.

There are two components to the program: a structured curriculum and a formal mentee-mentor pairing to facilitate the project completion. The curriculum in 2012-2013 consisted of 8 monthly half-day sessions on a wide variety of topics presented by speakers both external and internal to the department. Mentees and mentors also met regularly throughout the program to ensure support and progress on the projects.

The list of Mentees and Mentors last year and their subjects:

MeNTOr MeNTee

Dr. Suzette Cooke Dr. Leonie Herx Developing & validating a set of entrustable professional activities for palliative medicine: Phase One in designing a summative postgraduate learner assessment

Dr. Pam Veale Dr. Doan Le Mission Possible: Teaching students CanMEDS using missions sent from website or iPhone App

Dr. Karen Barlow Dr. Rebecca Sparkes Development of a proposal & business case for a newborn metabolic screening follow-up clinic at ACH

Dr. Karen Barlow Dr. Ellie Vyver Planning and development of a proposal for a new Sexual Health Clinic for ACH

Dr. Doug Strother Dr. Adam Spencer Validation of sonographic assessment of gastric volume in the paediatric patient by gastroscopic examination

Dr. Deb Dewey Dr. Tony Truong Predictive factors for Stem Cell Infusion Reactions in Paediatric Patients Undergoing Stem Cell Transplantation

Dr. Steve Martin Dr. Joseph Vayalumkal Communicating Infection Control Data Effectively. Are We Meeting the Needs of ACH Staff?

s p e c i a l f e a t u r e

Communicating Infection Control data effectively - are we Meeting the Needs of aCH Staff? a Quality Improvement Initiative

Dr. Joseph Vayalumkal (Infectious Diseases) was paired with Dr. Steven Martin (Gastroenterology) for the inaugural Department of Pediatrics mentorship program. The team embarked on a quality improvement project related to effective communication of data. The project revolved around the recognition that Infection Prevention and Control programs generate data that can be useful to front-line healthcare workers. However, these data are usually not easily accessible and their format may not be considered user-friendly to most healthcare workers. The objective of this project was to survey healthcare workers about the types of data they would find useful and how it should be shared. The pair met regularly to plan and discuss the implementation of the project. Although there were a few delays in meeting proposed deadlines, the survey was successfully completed. In total, 418 ACH staff took part in the survey. The project is now in the data analysis stage. ACH staff can look forward to easier access to infection prevention and control data which should hopefully lead to improved staff engagement/education regarding infection prevention practice and ultimately safer care for patients. ���

� Dr. Steven Martin – Mentor and Dr. Joseph Vayalumkal – Mentee

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 91

Awards and Recognitions

DEPARTMENT OF PAEDIATRICS ACADEMIC LEADERSHIP AWARD

Dr. Jong rho

DEPARTMENT OF PAEDIATRICS HUMANITARIAN AWARD

Dr. nalini singhal

DEPARTMENT OF PAEDIATRICS CLINICAL/ EDUCATOR AWARD

Dr. suzette cooke

DEPARTMENT OF PAEDIATRICS COMMUNITy PAEDIATRICS AWARD

Dr. thiru Govender

Dr. frank Dicke CCPE (Canadian Certified Physician Executive)

Dr. Vince Grant University of Calgary, Faculty of Medicine Full Time Faculty McLeod Award for Distinguished Achievement in Education

Dr. nicola WrightTop 40 Under 40 Avenue Magazine

Dr. ian mitchellCanadian Medical Association William Marsden Award in Medical Ethics

Dr. roxanne GoldadeUniversity of Calgary, Faculty of Medicine Alumnus of Distinction Award

Dr. Jean-francois LemayUniversity of Calgary, Faculty of Medicine Full Time Faculty Guenter Award for Distinguished Achievement in International Health

Dr. Julian midgley Queen Elizabeth II Diamond Jubilee Medal and Harold W. Ashenmil Award The Kidney Foundation of Canada

Dr. albert akieme Queen Elizabeth II Diamond Jubilee Medal

Dr. David stephure The Alberta Children’s Hospital Medical Staff Association Annual Award of Excellence

Page 94: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

Department of paeDiatrics | annual report 201392

GENERAL PAEDIATRICS PGME PROGRAM TEACHING AWARDS

Dr. Linda Bakovic Dr. George Prieur Paediatric Scholarship

Dr. Kathy tobler Dr. Husam Zaki (Sam) Darwish Clinical Teacher of the year Award — Subspecialty Paediatrics

Dr. Heidi angelesDr. Husam Zaki (Sam) Darwish Clinical Teacher of the year Award —Community Paediatrics

Dr. Dominique eustace Dr. Husam Zaki (Sam) Darwish Clinical Teacher of the year Award — Hospital Paediatrics

Dr. Jason silvermanClinical Teacher of the year Awarded to Subspecialty Fellows In Recognition of Outstanding and Dedicated

Teaching to the Paediatric Residents

Ume aWarDs

ASSOCIATE DEAN’S LETTER OF EXCELLENCE AWARD

Dr. Anke Banks

Dr. jonathan Darwant

Dr. Deborah Dewe

Dr. jonathan Darwant

Dr. Marielena DiBartolo

Dr. Estee Grant

Dr. josephine Ho

Dr. Nicole johnson

Dr. Charlene Kennedy

Dr. Leanna McKenzie

Dr. julian Midgley

Dr. Ian Mitchell

Dr. Danièle Pacaud

Dr. Doan Le

Dr. Lisa Lemieux

Dr. Amonpreet Sandhu

Dr. Kim Smyth

Dr. David Stephure

Dr. Pamela Veale

Dr. Andrew Wade

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 93

LETTERS OF EXCELLENCE AWARDS

Dr. Mark Anselmo

Dr. Candice Bjornson

Dr. Marielena DiBartolo

Dr. Estee Grant

Dr. Doan Le

Dr. Amonpreet Sandhu

GOLD AWARDS

Dr. Estee Grant

Dr. Doan Le

Dr. Lisa Lemieux

Dr. Marielena DiBartolo

Dr. Nicole johnson

BRONZE STAR AWARDS

Dr. Essa Al-Awad

Dr. Mark Anselmo

Dr. Candice Bjornson

Dr. jonathan Darwant

Dr. Marielena DiBartolo

Dr. jennifer D’Mello

Dr. Estee Grant

Dr. Charlene Kennedy

Dr. Doan Le

Dr. jean Mah

Dr. Leanna McKenzie

Dr. Ian Mitchell

Dr. Danièle Pacaude

Dr. Rebecca Perry

Dr. Amonpreet Sandhu

Dr. Kim Smyth

Dr. David Stephure

Dr. Pamela Veale

GOLD STAR AWARD

Dr. Lisa B. Lemieux

SILVER STAR AWARDS

Dr. Deborah Dewey

Dr. Doan Le

Dr. Lisa Lemieux

Dr. julian Midgley

Dr. Andrew Wade

STAFF AWARD

Dr. Hani Had

TEACHING 80+ HOURS

Dr. Adam Kirton

Dr. Lucie Lafay-Cousin

Dr. Victor Lewis

Dr. jean Mah

Dr. julian Midgley

Dr. Peter Nieman

Dr. Cheri Nijssen-jordan

Dr. Izabela Sztukowski

Dr. Graham Thompson

Dr. Pamela Veale

Dr. Christopher Waterhouse

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 95

The Department of Paediatrics Innovation Award

SUCCESSFUL PROjECTS FOR 2012

• Dr. susan Bannister and colleagues: “Strengthening Paediatric Undergraduate Education at the University of Calgary by Contributing to the National Undergraduate Paediatric Curriculum” (Education)

• Dr. stephen freedman and colleagues: “Assessing Dehydration at Triage Employing End Tidal CO2 Monitoring in Children with Gastroenteritis” (Research)

• Dr. adam Kirton and colleagues: “Healthy Infants and Children Clinical Research Program (HICCUP)” (Research)

• Dr. antonia stang and colleagues: “Traditional Research Nurses versus an Innovative Undergraduate Research Assistant Program: the Parent Perspective (the TRAIN study)” (Research)

this year, the Department of paediatrics introduced a new funding initiative to support an individual or group engaged in innovative projects related to provision of clinical care, education or research within the Department of pediatrics.

• Dr. Graham thompson and colleagues: “Heal Education and Literacy (Project HEAL); a Multi-Modal Educational Platform for Parents” (Education)

• Dr. alfred Yeung and colleagues: “The Effects of Cognitive Behavioural Therapy with Adjunctive Hypnotherapy on the Neurobiology of Adolescent Irritable Bowel Syndrome: A Pilot Study” (Clinical)

• Dr. Doan Le, Mike Paget, Pamela Veale. Hematology/Oncology Section Members: Mike Leaker, Nicola Wright, MacGregor Steele, Douglas Strother, Victor Lewis, Ronald Anderson, Lucie Lafay-Cousin, Tony Truong, Greg Guilcher: “The Mission Possible CanMEDS team”

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Page 98: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

DEPARTMENT OF PAEDIATRICS | ANNUAL REPORT 201396

Mission Possible App

Highlighted from this year’s recipients is dr. doan le and colleagues who have collaborated on an app in an innovative way to engage preceptors to teach roles and medical trainees to learn them.

The Mission Possible CanMEDS team

doan le, Mike Paget, Pamela Veale. Hematology/Oncology Section Members: Mike Leaker, Nicola Wright, MacGregor Steele, Douglas Strother, Victor Lewis, Ronald Anderson, Lucie Lafay-Cousin, Tony Truong, Greg Guilcher

Background

It is the expectation from the Royal College that trainees be taught and evaluated based on all CanMEDS roles: Medical expert, Communicator, Collaborator, Manager, Health advocate, Professional, and Scholar. Explicit teaching of all CanMEDS roles during a clinical rotation can be challenging.

Methods

Trainees are tasked with completing “missions” based on CanMEDS roles and then review with preceptors.

s p e c i a l f e a t u r e

During the Paediatric Hematology/Oncology Elective, agents will:

• CompleteeachandeveryMissionsafely

• RevieweachandeveryMissionwithaPreceptor

• Claimprize

• InitialpilotoftheMissionsonpaperbasedformat during student electives

• Collectfeedbackfromfacultyandtrainees

• Developanappforportabilityandeaseofuse “in the moment”

Mission Samples

• MEDICAL EXPERT: Observe bone marrow aspirate

• COMMUNICATOR: Take a history on how chronic disease has a effected child’s life

• COLLABORATOR: Meet the members of multidisciplinary team

• PROFESSIONAL: Reflect back on a circumstance that caused you distress or you felt unprepared to handle including what you would do differently or who can help next time

Page 99: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

• SCHOLAR: Describe a case in which the management plan was unclear and how you would look in the literature

• HEALTH ADVOCATE: List how you could advocate for resources for a patient seen in the clinic

• MANAGER: How would you plan your day if you have two consults in the ward, one in ER, a drop-in clinic patient, and presentation

Results

A total of 7 trainees (clerks or residents) were included in the pilot project. Trainees completed 4-7 missions during their rotation and made the following comments:

• “Reflectionisespeciallyimportantfordifficultcases.Good to debrief with others.”

• “Onlineaccessmightmakeiteasiertoremember.”

• “Ireallyenjoyedthemissionsbecauseitforcedmetopushmyself to look for opportunities to practice or watch others practice these roles.”

• “EmphasizedCanMedsRolesthatwedon’talwaysgetteaching on.”

• “Staffenthusiastictoengageinthe“Missions.”

The Future

Mission Possible can be used by other sections within the Alberta Children’s Hospital to connect with one another and to engage multiple trainees simultaneously.

In development is a website and iPhone App that would permit Missions to be distributed. The website or App will also be capable of tracking CanMEDS teaching in a variety of rotations.

For more information on the Innovation Award Program or the CanMEDS app visit this address link.http://www.ucalgary.ca/paed/Special_Feature-CanMEDS_App

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ANNUAL REPORT 2013 | DEPARTMENT OF PAEDIATRICS 97

�The CanMEDS app was presented as a poster at ICRE

(International Residency Conference); this is an image

element from the poster.

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Department of paeDiatrics | annual report 201398

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 99

New Department Faculty Members

Dr. susanne BenselerSection of Rheumatology

Dr. ping Wei chenSection of Emergency Medicine

Dr. seen chungSection of Emergency Medicine

Dr. Kristin evashukSection of Community Paediatrics

Dr. natalie forbesSection of Community Paediatrics

Dr. cara GilmanSection of Community Paediatrics

Dr. Leonora HendsonSection of Neonatology

Dr. russell LamSection of Emergency Medicine

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Department of paeDiatrics | annual report 2013100

Dr. Linda LoovereSection of Community Paediatrics

Dr. nadia LucaSection of Rheumatology

Dr. paola LucaSection of Endocrinology

Dr. ayman abou mehremSection of Neonatology

Dr. aleksandra mineykoSection of Neurology

Dr. Jane ngSection of Community Paediatrics

Dr. Laine racherSection of Community Paediatrics

Dr. swati rastogiSection of Community Paediatrics

Page 103: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 101

Dr. Lioba redelSection of Community Paediatrics

Dr. Lauren redgateSection of Community Paediatrics

Dr. naminder sandhuSection of Emergency Medicine

Dr. amelie stritzkeSection of Section of Neonatology

Dr. sumesh thomasSection of Neonatology

Dr. erika VorhiesSection of Cardiology

Dr. theresa WuSection of Hospital Paediatrics

Dr. Desiree YowSection of Community Paediatrics

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AnnuAl RepoRt 2013 | DepARtment of pAeDiAtRics 103

Research Funding

1. *2011-13 Impact of simulation-based skill acquisition instruction (SSAI) on competence in performing effective manual mask ventilation (MMV) in a randomized group of Neonatal Resuscitation Program (NRP) providers Amount: (Total): $ 25,000.00 Sponsor: Neonatal Resuscitation Program, Canadian Paediatric Society Role: Primary Investigator Harish amin

2. *2012-2014 An Internet-based Psycho-educational Game for Children with Juvenile Idiopathic Arthritis (JIA) and their Parents: A Randomized Controlled Trial Amount: $692,988 Source: Canadian Institutes of Health Research Role: Co-Applicants Stinson J, benseler S, Berard R, Campillo S, Dancey P, Duffy C, Feldman B, Huber A, Johnson N, luca N, McGrath P, Shiff N, Spiegel L, Tse S, Tucker L, Victor C. 

3. **2012-2017 Chronic Childhood Vasculitis: Characterizing The Individual Rare Diseases To Improve Patient Outcome.  Amount: $2,500,000 Source: Canadian Institutes of Health Role: Co-Primary Investigator benseler SM. Co Investigators: Cabral D, Foell D, Hancock R, Ross C.

4. **2010-2015 Team in Linking Exercise, Physical Activity and Pathophysiology in Childhood Arthritis a Canadian Collaborative Team (LEAP) Amount: $3,500,000 Source: Canadian Institutes of Health Research Role: Local Co-Investigator benseler SM. Co Investigators: C. Duffy, L. Tucker, R. Yeung, H. Mackay, A Baxter-Jones

5. *2012-2014 Canadian Malnutrition Task Force Amount: $40,050

Source: Funding through Canadian Nutrition Society Role: Primary Investigator: dr. dana boctor

6. *2012-2013 Development of a Patient Education Prototype in Intestinal Failure NAPSGHAN I Amount: $2,000 Source: In-Office Member Grant for Development of Patient Education Prototypes Primary Investigator: dr. dana boctor

7. *2010-2013 AHSI can Village health volunteers trained in integrated case management of childhood illness improve access to care for Africa’s most valuable children Funding (Total): $ 350,000.00 Sponsor: Canadian International Development Agency Primary-Investigator: Jen brenner, Co Investigator N Singhal

8. *2012-2013 Prognosticators of persistent concussion symptoms following paediatric minor traumatic head injury Amount: $17,700 Source: The Canadian Institutes of Health Research Role: Primary Investigator: R. Zemek RL , Freedman Sb (Co-Investigators), Osmond M, Vassilyadi M.

9. *2012-2013 Management of Acute Gastroenteritis: Synthesizing Evidence to Inform North American Practice Amount: $100,000 Source: The Canadian Institutes of Health Research (CIHR; funding reference #: 119808) Role: Primary Investigator: r. Freedman Sb Co-Primary investigators, Hartling L, Johnson D, Gouin S, Black K, Fitzpatrick E, Bialy L, Klassen T, Belanger F, Hilliard B, Jabbour M.

10. *2012-2013 Abdominal X-Ray Use and

EXTERNAL PEER-REVIEWED RESEARCH GRANTS

* Existing funding in 2012-13 ** New funding in 2012-13

All grant funding data shown below is based on submissions from Department of Paediatrics members. Grant funding obtained after June 30, 2013 is not included in this report.

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Department of paeDiatrics | annual report 2013104

Role: Primary-Investigator: R Bahm A, CO-SRA: Freedman Sb, Co-SRA: Guttmann A

14. *2011-2013 Inhaled Magnesium in Refractory Paediatric Acute Asthma Amount: $500,920 Source: Thrasher Research Fund Role: Primary Investigator: r Schuh S, Co- Investigator Freedman Sb, Co- Investigator Ducharme F, Co- Investigator Black K, Co- Investigator Johnson D, Co- Investigator Beer D, Co- Investigator Plint A, Co- Investigator Zemek R, Co- Investigator Guimont C, Co-Investigator Willan A, Co-Investigator Thompson G, Co-Investigator Coates A

15. *2010-2012 Isotonic versus hypotonic IV maintenance fluids in children: a randomized controlled trial Amount: $46,742 Source: Physicians' Services Incorporated Role: Co-Investigator r Geary D, Co- Primary Investigator, Co-Investigator Freedman Sb, Co-Investigator Beck C, Co-Primary-Investigator Freidman JN

16. *2010-2012 Electrolyte Maintenance Solution Administration Required in Low-Risk Children with Gastroenteritis?

Amount: $169,200 Source: Physicians' Services Incorporated Role: Primary- Investigator: r. Freedman Sb, Co- Investigator Boutis K, Co- Investigator Parkin P, Co-Investigator Goia C, Co- Investigator Atchison D, Co-Investigator Schuh S

17. *2012-2014 Ondansetron Use in Children with Dehydration in a Developing Country Amount: $100,000 Source: Bill and Melinda Gates Foundation Grand Challenges Explorations Grant Role: Primary Investigator: r. Freedman Sb, Bhutta Z.

18. **2013-2018 Ondansetron administration to children with gastroenteritis associated vomiting in EDs in Pakistan Amount: $446,956 Source: Thrasher Research Foundation  Role: Freedman Sb (PI), Willan A, Razzak J, Siddiqui E, Bhutta Z.

19. *2010-07 to 2013-07 Perioperative Ischemic Evaluation-2 (POISE-2) Amount: $7,800,000 Total: $3,600,000.00 Source: Canadian Institutes of Health Research Role: Site Investigator (University of Saskatchewan): gamble J

20. *2012-05 to 2012-08. Endotracheal Tube Palpation To Assess Endotracheal Depth In Paediatric Patients Amount Total: $4,250.00 Source: Deans Summer Research Project College of Medicine - University of Saskatchewan. Role: Principal Investigator: gamble J

21. *2008-2013 Early Life Experience and Child Development at 8 Years. Source: Calgary Children’s Imitative Amount: $40,000.00 (January 1, 2008 - December 31, 2013) Co-Investigators gibbard wb

22. *2008- 2013 Developmental Coordination Disorder: From Genes to Behaviour Amount: $1,135,866.00 Source: Canadian Institutes of Health Research Role: Co-Investigators lemay J-F; Collaborator: gibbard wb

23. *2010-2012 Little Movements - Lots To Learn: Validation Of A Parent Questionnaire To Screen For Developmental Coordination Disorder In Preschool Children Amount: $40,000.00 Source: Alberta Centre for Child, Family and Community Research Role: Co-Investigator: gibbard wb

24. *2010-2013 Can Adherence to PALS Guidelines be Improved by Team Training of Paediatric Resuscitation Team Members? Amount: $474 000 Source: Funding obtained from Heart and Stroke Foundation of Canada and Canadian Institutes of Health Research, 3 years, Principal-Investigator: gilfoyle, e

25. *2012 Canadian Hospital Injury Reporting and Prevention Program Source (CHIRPP) Amount: $398,077.87 Source: Public Health Agency of Canada Primary Investigator: dr. Jonathan guilfoyle

26. *2010-2014 Assessing and Improving the Quality of Cardiopulmonary Resuscitation (CPR) Delivered During Simulated Paediatric Cardiac Arrest using a Novel CPR Feedback Device Amount: $450,000 CAD Source: Heart and Stroke Foundation of Canada and Canadian Institutes of Health Research Role: Primary Investigators: dr. vincent grant, a Cheng Alberta Children’s Hospital, Dr. Jonathan Duff, Stollery Chldren’s Hospital, Dr. Farhan Bhanji, Dr. Ronald Gottesman, Montreal Children’s Hospital, Dr. Vinay

the Misdiagnosis Rate in Children with Constipation. Amount: $7,298 Source: The Hospital for Sick Children, Paediatric Emergency Medicine, Research Fund Role: Primary Investigator: r. Freedman Sb, Thull-Freedman J, Manson D, Schuh S, Rumantir M.

11. *2011-2015 Translating Emergency Knowledge for Kids (TREKK) Amount: $1,200,000 Source: Networks of Centres of Excellence (NCE) Program - Knowledge Mobilization Role: Co-Investigators: r. Klassen T, Hartling L, Jabbour M, Johnson D, Scott S, Sinclair D, Lang E, Freedman Sb, Black B, Gouin S, Stang A.

12. *2011-2013 Children with Acute Gastroenteritis: Predictors of increased length of stay in the emergency department Amount: $2,000 Source: IWK Health Centre Role: Primary-Investigator: r Schindler N, Freedman Sb (Co-Sra), Black, K

13. *2011-2013 Population Based Cohort to Determine Effect of ED Paediatric Gastroenteritis Strategies on Admission and Return Visit Rates Amount: $20,000 Source: Physicians Services Incorporated

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Nadkarni, Children’s Hospital of Philadelphia and Dr. Betsy Hunt, Johns Hopkins Children’s Hospital and the EXPRESS Investigators.

27. *1994-2013 Adverse Event Study, Laboratory of Diseases Control Amount: $10,0000 Source: Canadian Pediatric Society, IMPACT (Immunization Monitoring Program, Active) Role: Local-Primary- Investigator T Jadavji

28. *2009-2014 Stemming the epidemic of liver related morbidity and mortality in HIV-HCV co-infection: Is ART enough? Amount: $1,924,155.00 Source: Canadian Institutes for Health Research Role: Co-Investigator T Jadavji

29. *2011-2014 The Implementation and Evaluation of an Alberta Childhood Asthma Clinical Pathway Amount: $149,980.00 Source: AIHS Primary Investigator: dr. david Johnson Co-Investigator g Currie, Co-Investigator a Nettel-aguirre, Co-Investigator S Spier

30. *2011-2014 Combined Glucocorticoid Adrenergic Therapy

Amount: $150,000.00 Source: Husky Energy Chair in Child & Maternal Health Primary-Investigator: dr. david Johnson

31. *2012-2016 The Alberta Perinatal Stroke Project Amount: $750,000, Direct (during 2012-2013): $20,000 Source: Alberta Innovates Health Solutions Collaborative Research and Innovation Opportunities Project Role: Primary Investigator: Kirton a; Co-leads: Yager J, Andersen J, Collaborators: Brooks B, Dukelow S, Kosior J, Hagel B, Buchhalter J, Nettel-aguirre a, O’Grady K, Hill MD.

32. *2011-2014 Pathophysiology of Perinatal Stroke Amount Total: $150,000 Source: NeuroDev Net Role: Principal Investigator a Kirton, Co-Investigator K yusuf

33. *2008-2015 Natural History Study Of The Development Of Type 1 Diabetes; Sub-Study: Oral Insulin For Prevention Of Diabetes In Relatives At Risk For Type 1 Diabetes Mellitus Source: NIH, NIDDK Role: Site Primary-Investigators C Huang, Co-Investigator d Pacaud, Co-Investigator d Stephure, Co-Investigator J Ho

34. **2013-2016 Enhanced Care for Rare Genetic Diseases in Canada Amount: $11,853,890 Source: Genome Canada Role: Co-Applicant: M Innes

35. *2009-2014 Vascular effects of infection in paediatric stroke (VIPS) Amount: Direct (during 2012-2013): $18,000 Source: NIH Co-Investigators: a Kirton, Primary Investigator: H Fullerton, University of California at San Francisco

36. *2011-2015 Thrombolysis in paediatric stroke (TIPS) A safety study of tPA in acute childhood stroke Amount: Direct (during 2012-2013): $11,000 Source: NIH Role: Co-Investigator a Kirton, Primary Investigator: G deVeber, University of Toronto

37. *2011-2013 Diffusion tensor imaging of corticospinal tract integrity in perinatal stroke Amount: Direct (during 2012-2013): $10,000 Total: $40,000 Source: Canadian Institutes of Health Research Training Program in Genetics, Child Health, and Development. Graduate studentship (Ms. Jacquie Hodge) Primary-Investigator: a Kirton

38. *2011-2013 Expansion of a Canadian Multi-Regional Population-Based Cerebral Palsy Registry Amount: Direct (during 2012-2013): $20,000 Source: Public Health Agency of Canada Co-Investigators: a Kirton, M Shevell McGill University Z

39. *2010-2013 Pathophysiology of perinatal stroke Amount: Direct (during 2012-2013): $36,000 Total: $150,000 Source: NeuroDevNet Role: Principal Investigator a Kirton, Co-Principal Investigator a Nettel-aguirre

40. *2006/06-Present AML Risk of Infection Study Amount: $1,700 Source: Hospital for Sick Children, Toronto, ON Local Primary-Investigator: lewis, v

41. *2009-2013 Corneal Confocal Microscopy to detect Diabetic Neuropathy in Children Amount: Direct (during 2012-13): $45,000 Source: Juvenile Diabetes Research Foundation Total: $362,358 Co-Investigators: JK Mah, daniele Pacaud

42. *2009-2014 Phase 2 Study on the Clinical-Demographic, Epidemiology, Pathobiology, Neuroimaging Features And Outcome Of Acute Demyelination In Canadian Children Amount: Total: $460,000, Direct (during 2012-13): $125,000 Source: US FSH Society and Muscular Dystrophy Canada Local Primary Investigator: J K Mah, Primary Investigator: B Banwell , Hospital for Sick Children

43. *2009-2017 Longitudinal Study of the Relationship between Impairment, Activity, Limitation, Participation and Quality of Life in Persons with Confirmed Duchenne Muscular Dystrophy Amount: Direct (during 2012-13): $25,000 Total: $125,000 Source: US Department of Defense and Cooperative International Neuromuscular Research Group Primary Investigator: JK Mah Site, C MacDonald, University of California at Davis

44. *2011-2014 A Multicenter Collaborative Study on the , Expression Profiling, and Quality of Life in Paediatric Fascioscapulchumeral Muscular Dystrophy Amount: Direct (during

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site collaborator for Rheumatology Amount: Total Award Nationally: $3,733,300.00—with portion to ACH Source: Canadian Institutes of Health Research Role: Site collaborator for Rheumatology PM Miettunen

48. *2008-12 AHFMR Interdisciplinary Team Grant in Vaccine Design and Implementation Amount: $5,000,000.00 Source: Alberta Heritage Foundation for Medical Research Interdisciplinary Team Grant Competition. Role: Co-Investigator Jd Kellner, Collaborator Og vanderkooi

49. *2009-2014 Evaluation of Meningococcal C Conjugate Vaccine Programs in Canadian Children Amount: $699,655.00 Source: Canadian Institutes of Health Research Institute of Population and Public Health Operating Grant Role: Co-Investigator Jd Kellner, Co- Investigator Og vanderkooi

50. *2010-2015 Canadian Microbiome Initiative Amount: $2,484,542.00 Source: Canadian Institutes Of Health Research Emerging Team Grant Canadian Institutes for

Health Research. Role: Co- Investigator Jd Kellner

51. *2009-2012 PHAC/ Canadian Institutes of Health Research Influenza Research Network Amount: $10,800,000.00 Source: Canadian Institutes of Health Research Institute of Infection and Immunity & Public Health Agency of Canada. Role: Co-Investigator: S Kuhn, Co- Investigator O vanderkooi Co-Investigator Jd Kellner

52. *2008-present Hospital for Sick Children, Toronto, On Weekly Vinblastine for Chemotherapy Native Children with Progressive Low Grade Glioma Amount: $1,230 Role: Co-Investigators: lafay-Cousin L, Narendran A

53. *2011-13 Metformin in women with type 2 diabetes in pregnancy trial Amount: (Total): $1.78 million Source: Canadian Institutes of Health Research Role: Local-Co-Investigator a lodha, Site Primary Investigator L Donovan Primary Investigator: Denice S. Feig, University of Toronto

54. **2012 MiTy Kids: Metformin in Women with Type 2 Diabetes in Pregnancy Kids Trial Amount: $650 per patient) -2012 Source: Canadian Institutes of Health Role: Principal Investigator: Feig, D. (University of Toronto) Site collaborator: J Ho

55. *2010-2014 Metabolic Mechanisms of Functional Neuroprotection in Epileptic Brain Amount: Direct (during 2012-2013):$56,500 Total $300,000 Source: NINDS, NIH Co-Primary-Investigators: JM rho, DY Kim Barrow Neurological Institute, Phoenix, Arizona

56. *2006-12 Efficacy and safety of targeting lower arterial oxygen saturations to reduce oxygen toxicity and oxidative stress in very preterm infants: Canadian Oxygen Trial Amount: $3,691,500 Source: Canadian Institutes of Health Research Role: Schmidt, B.K., Roberts, R.S., Whyte, R.K., Asztalos, E.V., Shah, P., Solimano, A.J., Bairam, A., Seshia, M., Moddeman, D.M., Chiu, A., Roukema, H.W., Sauve, r.S., rabi, y., Harrold, J.E., Clarke, M.C.W., Kumar, M., Peliowski

57. *2008-13 CIHR Team in Maternal-Infant Care – Translating knowledge into improved care Amount (Total): $4,902,135.00 Source: Canadian Institutes Of Health Research Role: SitePrimary Investigator r Sauve, Project Lead) Primary Investigator: S. Lee, University of Toronto

58. *2010-15 CAP 11 years outcomes Amount (Total): $407,627.00 Source: Canadian Institutes Of Health Research Role: Site Primary Investigator r Sauve, Primary Investigator: B Schmidt, McMaster University

59. *2009-14 Alberta Sepsis Network Amount: $5,000,000.00 Sponsor: AHFMR Role: Co-Investigator r Sauve, Primary Investigator P Kubes, Site Lead Thomson gC (Team Members): gilfoyle, e and blackwood, J

60. *2011 – 2014 The Canadian Kidney Knowledge Translation and Generation Network (CANN-NET) Amount: $543,542 Source: Canadian Institutes of Health Research

2012-13): $ 65,000 Total: $96,669 Source: US FSH Society and Muscular Dystrophy Canada Local Primary Investigator: JK Mah

45. *2011-2016 Duchenne Muscular Dystrophy: Double –blinded, Randomized Trial to find Optimum Steroid Regimen Amount: Direct (during 2012-13): $2,500 Total: $50,000 Source US NIH Site Primary Investigator: JK Mah, R Griggs Co-Primary Investigators University of Rochester and Kate Busby, Newcastle upon Tyne

46. *2011-2012 Partners with Schools (COMPASS) – A Collaborative Mental Health Services Model Source: Funded by Canadian Institutes of Health Research Amount: $15,000.00 (September 1, 2011 - August 31, 2012) Co-Investigators: Mclennan J

47. *2006-2014 Steroid-associated Osteoporosis in the Paediatric Population Details: This is a multisite study, run from Ottawa with Dr Leanne Ward as the Principal investigator. It is CIHR funded for 5 years. I am a principal

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Co-Investigator– S Samuel, Principal Investigator: B Manns

61. *2011 – 2014 A Health Services Research Program for Paediatric Nephrology Amount: $50,000 (Infrastructure amount with matching funds from the Department of Pediatrics) Source: Kidney Foundation of Canada/ Canadian Institutes of Health Research /Canadian Society of Nephrology Role: Primary Investigator: S Samuel

62. *04/2010-03/2013 Pharmacogenetics of juvenile idiopathic arthritis – A genome wide association study on the efficacy and toxicity of methotrexate therapy Amount: $240,000 Source: Canadian Arthritis Network Role: Principal-Investigator H Schmeling, Co-Investigator P Miettunen

63. *2008-2013 Impact of (ACoRN) Acute Care of at Risk Newborn Education Program in Rural China Amount (Total): $180,000.00 Source: China joint Canadian Institutes of Health Research Role: Primary Investigator N Singhal

64. *2008-2014 The Impact of Maternal Nutrient Status during Pregnancy on Maternal Mental Health and Child Development Funding (Total): $4,999,998.00 Sponsor: AFHMR Role: Co-Investigator N Singhal

65. *2013 Charting the Territory – Determining and Documenting Trajectories For Families Where A Child Has a Life-threatening Condition Amount: funded for $23,000 per year, ending in 2013 Source: Canadian Institutes Of Health Research Role: Site Principal Investigator: Sharron Spicer

66. *2011-2021 Quality Indicators of ED Overcrowding Amount: $18,000.00 Source: NSERC Primary Investigator: dr. antonia Stang

67. *2011-2015 Translating Emergency Knowledge for Kids TREKK Amount: $86,801.89 Source: University of Manitoba Role: Principal-Investigator: Dr. antonia Stang Co-Director Johnson d, Co-Investigator Currie g, Co-Investigator

Freedman Sb, Co-Investigator Stang a

68. *2011-2013 Different Corticosteroid Dosing Strategies At Discharge For Acute Asthma Primary Amount: $5,000.00 Source: CAEP Investigator: dr. antonia Stang

69. *2011-2014 A randomized control trial to evaluate the efficacy of a social skills intervention group for childhood survivors of brain tumours Amount: $44,164 Source: Canadian Cancer Society Research Institute Co-Investigator: Barrera M, Strother d

70. *2010 Evaluating Processes of Care & the Outcomes of Children in Hospital (EPOCH) Amount: $3,266,764. Source: Grant awarded by Canadian Institutes Of Health Research, 4 years, Site Investigator Tobler, K

71. *2011–2013 Umbilical cord blood levels of angiogenic and antiangiogenic factors and risk of bronchopulmonary dysplasia in preterm neonates Amount: (Total): $25,000 Source: Angela Jone Memorial Clinical Research Award – The Lung

Association Role: Primary Investigator K yusuf

72. *2011-2014 Pathophysiology of Perinatal Stroke Amount Total: $150,000 Sponsor: NeuroDev Net Role: Primary Investigator a Kirton, Co-Investigator K yusuf

73. *2011-2013 Umbilical cord blood levels of angiogenic and anti-angiogenic factors and risk of retinopathy of prematurity Amount:  (Total):  $20, 259 Source: The Lions Sight Center Fund Role: Primary Investigator K yusuf

74. **2013-14 Paediatric Procedural Skills – Re-evaluating the Competencies Co-Investigator H amin Amount Total: $ 4,085.00 Source: Paediatric Consultants Education Grants, University of Toronto

75. **2012-2017 Predicting Persistent Postconcussive Problems in Pediatrics (5P) Amount: $1,273,705 Source: The Canadian Institute for Health Research (CIHR) Role: Primary Investigators: Zemek R, Osmond M, Anderson P, barlow K,

Barrowman N, Boutis K, DeMatteo C, Farion K, Freedman Sb, Gagnon I, Gravel J, Hoshizaki B, Keightley M, Klassen T, Meeuwisse W, Meehan W, Mikrogianakis a, Vassilyadi M, Johnson d, Plint A

76. ** 2013 –2018 Post-concussion syndrome affecting Youth: GABAergic effects of melatonin Amount: $875,392 Source: Canadian Institutes of Health Research Role: Primary Investigator barlow, KM, Co-Primary Investigator dewey, d. Co-Investigators: Brooks, B., Crawford, S., esser, M., Johnson, d.w., Kirk, v., Kirton, a. MacMaster F, Mikrogianakis, a. Nettel a

77. ** Development of a uniform histology scoring systems for Small Vessel CNS Vasculitis in adulthood and childhood. Amount: $40,128.10 US Source: Vasculitis foundation. Role: Primary Investigator: benseler SM, Twilt M, Hawkins C.

78. **2012-2015 An internet-based psycho-educational program for children with juvenile idiopathic arthritis (JIA) and their parents: A randomized controlled trial Amount: $614,303

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Yeung R, Harvey E, Paresh R, Tomlinson C, Sochett E, Howard A, Sung L, Stinson J, Furlan A, Grynpas M, Gahunia H.

81. **2012 What matters the most for parents, patients and clinicians in predicting the course of juvenile idiopathic arthritis? Amount: $54,366 Source: Canadian Initiative for Outcomes in Rheumatology Care Awareness/Advocacy/Education Grant. Role: Co-Primary Investigator: benseler SM. Co-Investigators: Guzman J, Berard R, Duffy C, Jurencak R, Oen K), Petty R, Shiff N, Tucker L.

82. **2009-2014 Linking Exercise, Physical Activity and pathophysiology in Juvenile Arthritis Source: A Canadian Collaborative Team grant CHIR funded grant Amount: $2,448,419 Role: Local Investigator: benseler S, Principal Investigator: Duffy C, Ottawa

83. **2013-2016 Treatment of cholesterol-dependent pulmonary surfactant dysfunction Amount total: $700,000 over 3 years 2013: $233,333

Source: Alberta Innovates Health Solutions Role: Collaborating scientist bjornson, C Primary Investigator: M. Amrein

84. **2012-2013 The Evolution of a Pulmonary Exacerbation: A Preliminary Analysis of Bacterial Population Dynamics Culminating in Acute Respiratory Perturbations Amount: Recruitment phase. $30,000 Source: Cystic Fibrosis Canada Role: Primary Investigator: M. Parkins, Co-investigator C. bjornson

85. **2013-2016 Learning and reinforcement in adolescents with Autism Spectrum Disorders Source: SickKids Foundation Amount: New Investigator Award, 2013-2016, Amount: $100k/annum, Role: Primary Investigator: Signe bray

86. **2013 Structure-function relationships in healthy brain development Amount: 2017, $29k/annum Source: NSERC Discovery Grant, 2013 Role: Primary Investigator: Signe bray

87. **2013 Sustaining child health

improvements in rural Uganda through a new Institute for Maternal, Newborn and Child Health Amount: $28 250 Source: CIDA/University Partnerships in Cooperation and Development Program Role: Primary Investigator Jennifer brenner

88. **2012 - 2014 Healthy Child Uganda (HCU); Scaling up comprehensive MNCH Programming to create a model District in Bushenyi, Uganda Amount Total: $4,666,574.00 Source: Canadian Institutes of Health Research Role: Primary Investigators Jen brenner Co-Investigator N Singhal

89. **2013-Present Canadian Children Inflammatory Bowel Disease Network: A Joint Partnership of CIHR and CH.I.L.D. Foundation $5,000,000.00 Source: Foundation for Children with Intestinal and Liver Disorders (CH.I.L.D.) and the CIHR Institute of Nutrition, Metabolism and Diabetes (INMD) Co-applicant, site director: dr. Jennifer debruyn

90. **2012-2013 General Operating Grant

Amount: $8083.00 Source: IDRU Primary Investigator: Jd butzner

91. **2009-2014 EXPRESS Paediatric Simulation Research Amount: $450,000 USD Source: Laerdal Foundation for Acute Medicine, Infrastructure Grant Role: a. Cheng, With: Dr. Elizabeth Hunt, Division of Critical Care Medicine, Johns Hopkins University and Dr. Vinay Nadkarni, Division of Critical Care Medicine, Children’s Hospital of Philadelphia

92. **2012 Research Fellowship Amount: $45 000 Source: Royal College of Physicians and Surgeons of Canada Role: Primary Investigator: Suzette Cooke

93. **2013-2018 Mild Traumatic Brain Injury in Children and Youth: Best Practices in Early Diagnosis and Treatment Amount: Amount: $2,148,468 Source: Canadian Institutes of Health Research & Hotchkiss Brain Institute - Team Grant Role: Principal Investigator: emery Ca Co-investigators: Meeuwisse WH, Dukelow S, Debert C, Brooks B,

Source: Canadian Institutes of Health Research Role: Co-Investigator. benseler SM. Principal Investigator: Stinson J. Collaborators: Campillo S, Duffy C, Feldman B, Hetherington R, Huber A, McGrath P, Palermo T, Spiegel L, Tse S, Tucker L, Victor C, Shiff N, Johnson N, Dancy P, Berard R.

79. ** 2012-2013 Towards developing MR imaging guidelines and outcome measures in juvenile idiopathic arthritis: a special interest pediatric research group. Amount: $24,954 Source: Canadian Institutes of Health Research (CIHR). Role: Co-Primary Investigator benseler SM, Principal Investigator: Doria A. Collaborators: Van Rossum M, Miller E, Rosenberg A, Roth J, Stinson J, Tse S, Yeung R.

80. **2012–2013 Diagnostic accuracy of peripheral quantitative computed tomography (pQCT) in pediatric osteoporosis Amount: $199,000 CAD. Source: Canadian Institutes of Health Research (CIHR). Role: Principal Investigators: Doria AS, Cheung A, Gordon C, Beyene J. Co-I. benseler SM Co-Investigators: Feldman B, Laxer R, Silverman E,

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Shneider K, Benson B, McKay C, Kang J, Barlow K, Babul S, Macpherson A, Hagel be, Iverson GL, Scott Iry CA

94. ** 2012-2013 Improving Patient Safety During Anesthesia: Inserting the Catheter Directly into the Lumbar Space Amount Total: $6,245.00 for 2012 to 2013-06-28 Source: Research Trust Fund Role: Primary Investigator: gamble J

95. **2013-2015 A Prospective Randomized Double Blinded Control Trial using Ketamine or Propofol for Electroconvulsive Therapy: Improving Treatment-Resistant Depression Amount: Total: $25,000.00 for 2013-09-02 to 2015-12-31 Source: Schulman Medical Research Fund Foundation Amount Total: $25,000.00 for 2013-03 to 2015-03 Source: Royal University Hospital Role: Primary Investigator gamble J

96. **2012 An Assessment of Prevalence and Clinical Care of Type 2 Diabetes in Albertan Children Amount: $50,000 Source: Women & Children’s Health Research Institute Role: Primary Investigator Toth, E. (University of

Alberta) Co-investigators: Ho, J. and Jetha, M.

97. **2012 Cerebral diaschisis in neonatal arterial ischemic stroke Amount Total: $7000, Direct (during 2012-2013): $7000 Source: Canadian Stroke Network Role: Primary Investigator: a Kirton

98. **2012 Impact of perinatal stroke on parents and families Amount Total: $12,000, Direct (during 2012-2013): $12,000 Source: AIHS and HBI Role: Primary Investigator: a Kirton

99. **2012 Quantification of gliosis in perinatal stroke and relationship to outcome Source: Alberta Innovates-Health Solutions Amount Total: $5200, Direct (during 2012-2013): $5200 Role: Primary Investigator: a Kirton

100. **2012 Time course of cerebral diaschisis in childhood arterial ischemic stroke Amount Total: $5200, Direct (during 2012-2013): $5200 Source: AIHS Role: Primary Investigator: a Kirton

101. **2012-2014 Understanding the neurophysiology of paediatric migraine with TMS Amount Total: $136,000, Direct (during 2012-2013): $68,000 Source: CIHR Training Program in Genetics, Child Health, and Development. Clinical Research Fellowship (Dr. Thilinie Rajapakse) Primary Investigator: a Kirton, Co-Investigator K barlow

102. **2012-2015 Enhancement of developmental motor plasticity in perinatal stroke with Transcranial Direct Current Stimulation Amount Total: $270,000, Direct (during 2012-2013): $90,000 Source: Heart and Stroke Foundation Role: Primary Investigator: a Kirton, Co-Investigator: d dewey

103. **2013 Cerebrovascular complications of bacterial meningitis in children Total: $5200, Direct (during 2012-2013): $5200 Source: Alberta Innovates-Health Solutions Role: Primary Investigator: a Kirton

104. **2013 Resting state fMRI motor network analysis in perinatal stroke Role: Primary Investigator: a Kirton Source: NSERC Create IT3 Graduate Studentship Direct (during 2012-2013): $12,000 Total $12,000.

105. **2013-2015 Robotic assessment of proprioceptive dysfunction in children with perinatal stroke Role: Primary Investigator: a Kirton Source: Cerebral Palsy International Research Foundation Direct (during 2012-2013): $50,000 Total: $100,000

106. **2013 BDNF genetics of neuroplasticity in cerebral palsy Source: Robertson Fund for Cerebral Palsy, Hotchkiss Brain Institute Amount: 1 year, $30000 CDN (July 2013 – June 2014) Role: Primary Investigator: Kirton a, Hill M

107. *2012 International Maternal Newborn Stroke Registry Amount: 2 years, $40000 Source: World Federation of Neurology Role: Primary Investigators:

Bushnell C, deVeber G, Kirton a

108. **2013 GeoSentinel Surveillance program Amount: $6600 estimate based on enrolment projections Source: PHAC provided a grant to the CDC/ISTM Role: Local Primary Investigator S Kuhn

109. **2013-2014 Travellers Who Visit Friends and Relatives and Their Acceptance of Specific Preventive Measures - Substudy. Amount: $1,200.00 Source: Substudy of PHAC Grant Role: Local Primary Investigator S Kuhn

110. **2013-2014 Travellers Who Visit Friends and Relatives and Their Acceptance of Specific Preventive Measures Amount: $10,000.00 Source: PHAC Role: Local Primary Investigator S Kuhn

111. **2012-2013 Programme Intégré de formation clinique chirurgicale de base (CCB) aux étudiants de médecine en stage de chirurgie de la FSSA pour répondre aux besoins sanitaires haïtiens de première ligne. Amount: $24,750.00

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Source: CBIE Govt Canada Role: Primary Investigator lemay J-F

112. **2012-2013 Programme Intégré de formation neurologique de base pour les étudiants de médecine de la FSSA afin de répondre aux besoins sanitaires haïtiens de première ligne. Amount: $24,780.00 Source: CBIE Govt Canada Role: Primary Investigator lemay J-F

113. **2012-2013 Education médicale pour les professeurs d’Haïti: nouvelle approche Source: CBIE Govt Canada Amount: $24,650.00 Role: Primary Investigator lemay J-F

114. **2012-14 Seminal Canadian Recommendations for Evidence–Based Examination of Neonates for Retinopathy of Prematurity (SCREEN–ROP) Study Amount Total: $455,000.000 Source: Canadian Institutes of Health Research Role: Site Primary investigator: a lodha, Site Co investigator: A Ells Primary Investigators: Kourosh Sabri, McMaster University

115. **2012-13 Caring for late preterm infants: public health nurses’ and Parents’ experiences Premji Amount Total: $40,000.00 Source: Alberta Centre for Child, Family and Community Research Role: Co Investigators: a lodha, Shahirose

116. **2012-17 Enhancing Breast Milk Production Domperidone in Mothers of Preterm Neonates (EMPOWER Study) Amount Total: $999,454.00 Source: CIHR Role: Site Primary investigator: a lodha, Co Investigator: J Boulton Primary Investigators: Elizabeth Asztalos, University of Toronto

117. **2014-2015 Trends in Oxygen Saturation in Healthy Term Infants in the First Few Days of Life: The “TOST” study Amount: $10,000 Source: Sandra Schmirler Foundation Grant Role: Loganathan P, Al Awad E, Fajardo C, Lefebvre C, lodha a, Nair V, Nettel-aguirre, Ratslaf K, wainer S, Young M, rabi y

118. **2012-2013 Validation of The Standardized Universal Pain Evaluations For Rheumatology Providers For Children And Youth (Super-Kidz) Amount: $49,992 Source : Canadian Arthritis Network, Discovery Advancement Program Role: Principal Investigator: Stinson J Co-Investigators: Luca N, Feldman B, Benseler S, Bayoumi A, Beaton D, Campillo S, Leblanc C

119. **2013–2018 Alberta Program in Youth Sport and Recreational Injury Prevention Amount: $2,425,000 Source: Alberta Innovates Health Solutions Collaborative Research and Innovation Program Role: Collaborative Co-Leads: emery Ca, Hagel be Collaborative Members: Meeuwisse WH, McCormack G, Rowe BH, Nettel-Aguirre A, Voaklander D, Finch C, Verhagen E, Macpherson A, Groff P, Goulet C, Kang J, McKay C, Richmond SA, Schneider K, Russell K, Doyle-Baker PK, Babul S, Marshall D, Currie gr, Ferber R.

120. **2013 Collaborative Team - Letter of Intent, Alberta Provincial Paediatric EnTeric Infection

Team (APPETITE): Moving into the Future - Epidemiology, Emerging Organisms, and Economics Amount: $24,783 Source: Alberta Innovates – Health Solutions Role: Primary Investigators Freedman Sb, Chuck A, Lee B, Johnson d, Currie g, Talbot J, Jiang J, Dickinson J, Kellner J, MacDonald J, Svenson L, Chui L, Louie M, Lavoie M, Eltorki M, vanderkooi O, Tarr P, Tellier R, Ali S, Drews S, graham T, Pang X.

121. **2013-2018 Magnesium Nebulization in Management of Paediatric Asthma – MagNUM PA Trial Amount: $2,137,058 Source: The Canadian Institute for Health Research Role: Primary Investigator: Schuh S, Co-Investigators: Freedman Sb, Zemek R, Plint A, Johnson d, Thompson g, Ducharme F, Gravel J, Klassen T, Curtis S, Beer D, Black K, Coates A, Willan A.

122. **2013-2014 Prenatal Cigarette Smoke Exposure and Neonatal Control Amount: PER YEAR: $30,000 Source: The Lung Association, Alberta and NW Territories Role: Primary Investigator Su Hasan

123. **2013-2014 Infant Car Safety Seats and Cardiorespiratory Events in Preterm Infants Amount: PER YEAR: $30,000 Source: The Lung Association, Alberta and NW Territories Role: Primary Investigator Su Hasan

124. **2013-2014 Virtual Peer-to-Peer (VP2P) Support Mentoring for Adolescents with Juvenile Idiopathic Arthritis: A Feasibility Pilot Randomized Controlled Trial Amount: $99,987 Source: Canadian Institutes of Health Research Role: Principal Investigators: Stinson J & Bell M, Co-investigators: Ahola Kohut S, Junkin L, Spiegel L, Amaria K, Kaufman M, Victor J, Cooper D, luca N, Forgeron P, Marcinko

125. ** 2013-2016 Paediatric obesity program evaluation Amount: $300, 000 Source: BMO Research Prize in Healthy Living Role: Principal Investigator: Reimer, R. Co-investigators: Elliott, C., MacMaster, F., Ho, J., Jelinski, S., Edwards, A.

126. **2013 The Canadian Neuromuscular Disease

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Registry Amount Total: $30,000, Direct (during 2012-2013):$6000 Role: Primary local Investigator: JK Mah, Primary Investigator L Korngut

127. **2013-2014 STEADFAST: A pilot randomized clinical trial on Stacking Exercises Attenuate the Decline in Forced Vital Capacity and Sick Time. Amount: $30,000, Direct (during 2012-13): $3000 Source: Children’s Hospital of Eastern Ontario Role: Site Primary Investigator: JK Mah, Primary Investigator: Sheeri Katz

128. **2013-2017 Ontario Child Health Study Sequel. Amount: $5,312,446.00 Source: Canadian Institutes of Health Research Role: Co-Investigator Mclennan J

129. **2012-2013 Ontario Child Health Study Sequel preparation grant Amount: $100,000.00 Source: Canadian Institutes of Health Research Role: Co-Investigator Mclennan J

130. **2012-2013 Suicide Prevention in Canada Youth: Options and

Evidence. Amount: $100,000.00 Source: Canadian Institutes of Health Research Role: Co-Investigator Mclennan J

131. **2012-2013 Improving the mental health of Canadian children and adolescents: A research synthesis Amount: $100,000.00 Source: Canadian Institutes of Health Research Knowledge Synthesis Grant Role: Co-Investigator Mclennan J

132. **2012-2013 Canadian Pediatric Society’s Surveillance Program on Periodic Fevers Amount: $ 5000 Source: Canadian Pediatric Society Role: Principal investigator Paul Dancey, Co-investigators Marco Gattorno, Anne Junker, Ronald Laxer, Paivi Miettunen

133. **2012-2017 Neurodevelopment of preschoolers exposed perinatally to bisphenol A and phthalates: Interactions with diet and neurotoxicant co-exposures. Amount: $1,271,880 Source: Canadian Institutes of Health Research Role: Primary Investigator Martin JW, Co-Investigators: Dewey D,

Dinu I, Field C, Giesbrecht GF, Kaplan B, Kinniburgh D, Letourneau L., Yasui Y

134. **2012-2013 Clinical Trials Support Amount: $1,823.19 (USD) Source: 2NCI (US), Children’s Oncology Group Chair Grant Primary Site Investigator: Strother, D

135. **2013-present Children’s Oncology Group, Chair Amount: $11,100 Source: NIH / COG Role: lafay-Cousin, l

136. **2012-2020 POETIC A Phase I Study Using Plerixafor as a Chemosensitizing agent for Relapsed Acute Leukemia and MDS in Pediatric Patients Amount: $4,074.80 Role: Primary Investigator Narendran, a

137. **2012-2017 Modulation of Brain-Specific ATP-Sensitive Potassium Channels by Physiological Stereoisomers of the Primary Ketone Body Beta-Hydroxybutyrate Amount Total: $712,613, Direct (during 2012-2013): $109,832 Source: Canadian Institutes for Health Research Role: Primary Investigator: JM rho

138. **2013 – 2018 Canadian National Transplant Research Program: Increasing Donation and Improving Transplantation Outcomes Amount: $14,270,000 Source: Canadian Institutes of Health Research Role: Co-Applicant– Susan Samuel

139. **2012-13 Optimizing Outcomes of Children who Require Live-saving Complex Interventions Amount Total: $10,000.00 Source: Alberta Innovates-Health Solutions Role: Site Primary investigator: r Sauve PI: CMT Robertson, University of Alberta

140. **2013 Preclinical validation and optimization of the ketogenic diet in the treatment of infantile spasms. Amount Total: $5000, Direct (during 2012-13): $5000 Source: University of Alberta studentship-Patricia Baccus Role: Primary Investigator: MH Scantlebury

141. **2013 Preclinical validation and optimization of the ketogenic diet in the treatment of infantile spasms.

Amount: Total: $7250, Direct (during 2012-13):$7250 Source: Branch Out Neurological Foundation-Patricia Baccus Role: Primary Investigator: MH Scantlebury

142. **2012 - 2014 Identification of Barriers and Facilitators for Education of Nurses in Care of Sick and At-Risk Newborn Babies in India Amount Total: $ 16,000.00 Source: Indo-Canadian Shashtri Institute and WHO Role: Co Investigator N Singhal

143. **2013 - 2014 Beta Testing of Helping Babies Survive Program Amount Total: $20,000.00 Source: American Academy of Pediatrics/Laerdal Foundation Role: Co Investigator: N Singhal

**2012-14 A family integrated care model for neonatal intensive care units Amount Total: $349,982.00 Source: Canadian Institute of Health Role: Co Investigator: a Soraisham Primary Investigator: S Lee, University of Toronto

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INTERNAL RESEARCH GRANTS

* Existing funding in 2012-13 ** New funding in 2012-13

All grant funding data shown below is based on submissions from Department of Paediatrics members. Grant funding obtained after June 30, 2013 is not included in this report.

12. *2011-2013 Immunity and History to Routine Childhood Vaccinations in Children with Inflammatory Bowel Disease Amount: $49,026.00 Source: Alberta Children's Hospital Foundation Role: Co- Primary-Investigator S Kuhn, Co- Primary-Investigator J debruyn

13. *2011-2014 Biological Markers Of Paediatric Cerebrovascular Inflammation And Stroke Amount: $36,095 Source: Alberta’s Children’s Hospital Research Institute Principal Investigator: Kirton a. Collaborators: Mineyko a. DeVeber G, Narendran a, Schmeling H. Collaborator. benseler SM

14. *2006-13 Long-Term Outcomes Of Infants With Chronic Lung Disease Amount: (total) $ 20,000.00 Source: Alberta Children’s Hospital Foundation Role: PRINCIPAL-INVESTIGATOR: a lodha, Co-Investigator: r Sauve

15. *2011-13 Meta Analysis: Metformin Exposure and Immediate Neonatal Outcomes Amount: (Total): $ 3,000.00 Source: Alberta Children’s Hospital Research Institute Role: Principal-Investigator: a lodha

1. *2011–2013 Oxidant And Anti-Oxidant Levels In Preterm Infants Before And After A Blood Transfusion Amount (Total): $43,554 Source: Alberta Children’s Hospital Research Institute Role: Co-Investigator: albert akierman, Richard Krause

2. *2011-2015 Impact of Emergency Department Probiotic Treatment of Pediatric Gastroenteritis on Daycare Attendance: Randomized Controlled Trial and Economic Analysis. Amount: $46,673 Source: Alberta Children’s Hospital Foundation Role: Co- Primary-Investigator Johnson D, Co- Investigator Sherman P, Co-Investigator Willan A, Co-Investigator Mittmann N, Co- Investigator Schuh S, Co-Primary- Investigator Freedman Sb

3. *2012 Simulation for Family Centered Care: Improving Caregiver Skills, Self-Efficacy and Quality of Life using a Practice-Until-Perfect Intervention for Seizure Management in the Home Environment Amount: $91,337 Source: Alberta Children’s Hospital Foundation

4. Role: Site Investigator with:

Primary Investigator Dr. vincent grant, Dr. Elaine Sigalet, Dr. Tyrone Donnon, University of Calgary.

5. *2009-2012 Can Umbilical Cord Blood Levels Of Angiogenic Factors And Endothelial Progenitor Cells (Epcs) Predict Risk Of Bronchopulmonary Dysplasia In Preterm Neonates? Amount (Total): $9958 Source: 2008 CLS (Calgary Laboratory Services) Health Services Research Funding Competition Role: Co-Investigator: Noureddine Berka and Faisal Khan, Immunogenetics and Histocomapatibility Lab, Calgary Laboratory

6. *2010-2013 A Study Of Endothelial Progenitor Cells And Factors Affecting Their Levels In Pregnant Women Who Smoke And Preeclampsia Amount (Total): $30,000 Source: Alberta Children’s Hospital Research Institute Role: Co-Investigator: Sue Ross, Noureddine Berka, Faisal Khan

7. *2011-2015 Non-HLA Immunogenetic Biomarkers Important for Pathogenesis and Therapy of Complications of Paediatric Hematopoietic

Cell Transplantation Amount: $19,440 Source: Alberta Children’s Hospital Foundation, Childhood Cancer Collaborative Role: Co-Investigator: Khan F, lewis, v

8. *2009-2013 Transcranial Magnetic Stimulation: Study and treatment of Childhood Neurological disorders Amount: $500,000 Direct (during 2012-2013): $100,000 Source: Alberta Children’s Hospital Foundation Role: Principal-Investigator a Kirton

9. *2011-2014 Biological Markers of Perinatal Stroke Amount (Total): $50,000 Source: ACHRI/Alberta Children’s Hospital Foundation Role: Primary Investigator a Kirton, Co-Investigator K yusuf

10. *2011-2013 Clinical Review and Cost Evaluation of a Paediatric Home Parenteral Therapy Program Amount: $25,000.00 Source: Department of Paediatrics Emerging Needs Fund

11. Role: Principal-Investigator: S Kuhn (Co-Principal-Investigator)

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Involved In Metabolism On The Efficacy And Toxicity Of Methotrexate Source: Alberta Children’s Hospital Research Institute Amount: $45,217 Role: Primary Investigator H Schmeling, Co-Investigator P Miettunen, Co-Investigator N Johnson

23. *2009-2012 Effect of Fluid Boluses on Cardiac Output and Heart Rate Variability in Newborns. A prospective Observational Study Amount (Total): $16,240.00 Source: Alberta Children's Hospital Foundation Role: Co-Investigator: N Singhal

24. *2011-13 Impact Of Central Line Bundle (A Quality Improvement Initiative) On The Incidence Of Central Line Associated Blood Stream Infection (CLA-BSI) In The Neonates Admitted To Neonatal Intensive Care Unit (NICU) Amount: (Total): $3,000.00 Source: Alberta Children’s Hospital Research Institute Role: Principal-Investigator: a Soraisham

25. *2011-2021 Quality Indicators of ED Overcrowding Amount: $15,000.00

Source: AHS Role: Principal-Investigator Dr. antonia Stang

26. *2012-13 Establishing N-Telepeptide Reference Ranges in Health Children in Calgary Amount: $44 000 Source: Alberta Children’s Hospital Research Institute Role: Principal-Investigator Cristina Stoian

27. *2011-2012 Appendicitis in the Canadian Paediatric Population: An Analysis Using National Administrative Data Amount: $3,000.00 Source: Alberta Children’s Hospital Research Institute Principal-Investigator: dr. graham Thompson

28. *2010-2013 Immunity and History to Routine Childhood Vaccinations in Children with Inflammatory Bowel Disease. Amount: $49,026.00 Source: Alberta Children’s Hospital Research Institute Role: Co-Investigator: Og vanderkooi

29. *2012 AMA's Emerging Leaders in Health Promotion grant provided to Jonathan Seto, Medical Student, University of Calgary  Amount: $1000.00 Source: University of

Calgary Role: Physician mentor: dr. J. vayalumkal

30. *2012 IBD Research Support Amount Balance: ($5,484.55) Source: Department of Paediatrics Role: Principal-Investigator: dr. Iwona wrobel

31. *2011-2013 Can Changes In Pulmonary Function After A Loading Dose Of Caffeine Predict Extubation Outcome In Preterm Infants? Amount (Total): $3000 Source: Alberta Children’s Hospital Research Institute Role: Primary Investigator: K yusuf

32. **2012 – 2014 The Canadian Childhood Nephrotic Syndrome Project Amount: $20,000 Source: University of Calgary – Non-competitive funding Role: Principal Applicant: Roy vi baay Chair for Kidney Research

33. **2012 Strengthening Paediatric Undergraduate Education at The University Of Calgary By Contributing To The National Undergraduate Paediatric Curriculum. Amount: $25 000

Concussion Symptoms? A Pilot Study To Refine A Clinical Prediction Rule, The 4C Tool Amount: $47,780 Source: Alberta Children’s Hospital Research Institute Co-Primary Investigator: a Mikrogianakis, Co Primary-Investigator K barlow

20. ** 2012 –2013 Determining the Effect of a Targeted Video on Satisfaction with Transition from Paediatric to Adult Endocrine Care for Patients with Type 1 Diabetes Mellitus Amount: $2,199.00 Funding source: Alberta Children’s Hospital Research Institute Role: Principal Investigator d Pacaud, Co-Investigator J Ho, K Winston

21. *2011 – 2014 Screening for Markers of Kidney Disease among Aboriginal Children and Youth: A Pilot Project Amount: $18,800 Source: University of Calgary, Petro Canada Community Innovator Award Role: Co-Investigator: S Samuel

22. *06/2009-03/2013 Pharmacogenetics of Juvenile Idiopathic Arthritis and Juvenile Dermatomyositis – The Influence Of Polymorphisms In Genes Of Enzymes

16. *2011-13 Overcoming Surfactant Inhabitation In Neonates And Infants – A Clinical Prospective Cohort Study With An Animal Model Correlate Role: Principal-Investigator: a lodha Amount: $49,200.00 Source: Alberta Children’s Hospital Research Institute

17. *2012-2013 Peak Serum Bilirubin As An Indicator Of Hypoxic Ischemic Amount: $3000 Source: Alberta Children’s Hospital Research Institute Investigators: Loganathan P, Al Awad E, Fajardo C, Lefebvre C, lodha a, Nair V, Nettel-aguirre, Ratslaf K, wainer S, Young M, rabi y

18. *2009-2013 Paediatric Neurology Residents and Faculty Professional Development Grant Amount: Direct (during 2012-13): $15,600 Total: $60,000 Source: University of Calgary Local sub-Investigator: JK Mah

19. *2011-12 Can We Foresee Which Children Will Have A Favourable Recovery Following A Mild Traumatic Brain Injury And Which Will Go On To Have Post-

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Source: Department of Paediatrics Innovation Award, University of Calgary Role: Co-applicants: Primary Investigator - Susan bannister, David Topps, Nicole Johnson, glenda bendiak, Julian Midgley

34. **2012-13 The Use Of Computerized Cognitive Testing In The ED To Predict Recovery Following A Mild Traumatic Brain Injury? A Study To Refine A Clinical Prediction Rule, The 4C Tool Amount: $43,500 Source: Alberta Children’s Hospital Foundation Role: Co-Principal-Investigator K barlow

35. **2012-14 Optical Imaging in Post-Concussion Syndrome In Children Amount: $63,500 Source: Alberta Children’s Hospital Foundation Role: Co-Principal-Investigator K barlow

36. **2012-14 Novel Neuroimaging Strategies To Detect Biomarkers Of Recovery Following Treatment With Melatonin In Post-Concussion Syndrome Amount: $33,500 Source: University of Calgary (U of C) Role: Principal-Investigator K barlow

37. **2012-14 Paediatric Brain Injury Catalyst Grant Amount: $100,000 Source: Alberta Children’s Hospital Foundation Role: Principal-Investigator K barlow

38. **2013 Learning And Reinforcement in Adolescents with Autism Spectrum Disorders Amount: $18k Source: University of Calgary, University Research Grants Committee (URGC) seed grant Role: Principal-Investigator Signe bray

39. **2012 In support of Serologic Protection to Routine Vaccinations in Children with Inflammatory Bowel Disease Amount: $10,000.00 Source: Alberta Children’s Hospital Department of Paediatrics Emerging Needs Fund Role: Principal-Investigator: JC debruyn

40. **2012 – Present An Evaluation of the Role of Paediatric Transient Elastography in Assessing Cystic Fibrosis Associated Liver Disease in Children with Cystic Fibrosis. Amount: $3,000 Source: Alberta Children’s Hospital Research Institute Small Research Grant

Role: Principal-Investigator: JC debruyn; Co- Investigators: Simon lam, Helen Machida, Robert Myers, Clara Ortiz, S Martin.

41. **2012/2013 Assessing Dehydration at Triage Employing End Tidal CO2 Monitoring in Children with Gastroenteritis Source: Department of Paediatrics Innovation Award, University of Calgary Amount: $24,925 Co-Investigators: dr. Stephen Freedman, david Johnson, angelo Mikrogianakis

42. **2012-2013 Neurodevelopment Of Children Perinatally Exposed To Environmental Neurotoxicants: A Pilot Project In Support Of A CIHR Proposal. Amount: $3,000 Source: small grants competition, Alberta Children’s Hospital Research Institute Role: PRINCIPAL-INVESTIGATOR: giesbrecht g, Co-Investigators: dewey d, Martin J, letourneau N, Kaplan bJ.

43. **June 2013 – June 2013 Psychological Distress and Cortisol Among Pregnant Women With Inflammatory Bowel Disease Amount: $17,883 Source: University of

Calgary Role: PI: giesbrecht, g.F., Seow, C & leung, y

44. **2011-2014 Combined Glucocorticoid Andrenergic Therapy (Conjugate) Team Amount: $150,000.00 Source: U of C/AHS New Emerging Team grant Role: Principal-Investigators: d Johnson, a Stang

45. **2013-2014 HICCUP: Healthy infants and Children Clinical Research Program Amount: $25,000 Source: Dept of Paediatrics Innovation Award, Direct (during 2012-2013): $12,000 Role: Principal-Investigator: Kirton a; CI: Johnson d, Herpinger L, Denys J

46. **2012 – June 2013 Is Salivary Useful In Predicting Serum Cortisol for The Diagnosis Of Adrenal Insufficiency In Preterm Neonates Of 32 Weeks Of Gestation Or Less Amount: $49, 981.00 Source: Alberta Children’s Hospital Foundation Role: Principal-Investigator: d Pacaud, Co-Investigator H amin

47. **10/2012-09/2014 Novel Diagnostic Approaches in Childhood Granulomatosis With

Polyangiitis Source: $20,000 Source: ACH Foundation/Dawson Jarock Award Role: Principal-Investigator Co-Investigator: Marvin Fritzler, Susan Samuel, Paivi Miettunen, Aurora Fifi-Mah

48. **2012 Traditional Research Nurses versus an Innovative Undergraduate Research Assistant Program: the Parent Perspective (the TRAIN study) Amount: $24,662 Source: Department of Paediatrics Innovation Award, University of Calgary Role: Principal-Investigator r. Stang A, Thompson g, Johnson D, Freedman Sb, Mikrogianakis a, Williamson J.

49. **2012 Teaching CanMEDS Roles Using Mission Impossible In Paediatric Hematology/Oncology. Amount: $5470.00 Source: Department Of Paediatrics Innovation Award, University of Calgary Principal-Investigator: veale PM

50. **Multimedia Educational Platform In The Paediatric Emergency Department Amount: $44,894.00 Source: ACHF

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Role: Principal-Investigator: dr. graham Thompson

51. **Chronic Abdominal Pain of Childhood: Evaluation in the Emergency Department Amount: $3,000.00 Source: Alberta Children’s Hospital Research Institute Role: Principal Investigator: dr. graham Thompson

52. **2011-Ongoing Test Characteristics of The Alvarado Score, The Paediatric Appendicitis Score And The Lintula Score Based Amount: $3,000.00 Source: Alberta Children’s Hospital Research Institute Role: Principal Investigator: dr. graham Thompson

53. **2013-2015 Hematological profile of appropriate for gestational age infants born to mothers with early onset preeclampsia Amount (Total): $2985 Source: Alberta Children’s Hospital Foundation, Alberta Children’s Hospital Research Institute. Co-Investigators: Mountasser Al-Mouqdad, Adnan Mansoor

54. **2012 The Effects of Cognitive Behavioural Therapy with Adjunctive Hypnotherapy on the Neurobiology of Adolescent Irritable Bowel

Syndrome: A Pilot Study Amount: $25,000 Source: Department of Paediatrics Innovation Award Role: alfred yeung, Kathleen Schwartzenberger, Frank McMaster, adam Kirton

55. *2009–2013 Profile Of Cytokines And Angiogenic Factors In Preeclampsia And Pregnant Women Who Smoke Amount: (Total): $45,000 Sponsor: Calgary Health Region (CHR) perinatal funding competition Role: Primary-Investigator: K yusuf, Co-Investigator: Majeeda Kamaluddeen

56. **2012- 2013 Impact of Growth Hormone on Adult Bone Quality in Turner Syndrome – A retrospective Cohort Study Using High Resolution Peripheral Quantitative Computed Tomography Amount: $12,481 Source: Alberta Children’s Hospital Research Institute Role: Primary Investigator d Stephure, Co-Investigator d Pacaud

57. **2013-2015 Umbilical Cord Blood Levels Of Cortisol and Hemodynamic Status On Day 1 In Preterm Infants < 31 Weeks Gestation: A

Prospective Observational Study Amount (Total): $3000 Source: Alberta Children’s Hospital Research Institute Role: Co -Investigator: Saranya Manickaraj

**2013-2015 Neonatal Outcomes in preterm infants less than 34 weeks gestation born to preeclamptic mothers who smoke Amount (Total): $2962 Source: Alberta Children’s Hospital Research Institute. Co -Investigator: vrinda Nair

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OTHER EXTERNAL RESEARCH GRANTS

* Existing funding in 2012-13 ** New funding in 2012-13

All grant funding data shown below is based on submissions from Department of Paediatrics members. Grant funding obtained after June 30, 2013 is not included in this report.

1. *2010-2014 Inhaled Nitric Oxide for the Prevention of Bronchopulmonary Dysplasia in Preterm Infants Requiring Mechanical Ventilation or Positive Pressure Support on Day 5-14 after Birth Amount: Received to-date (November 2013), $997,435.04 Currently (November 2013) available: $525,052.94 Excluding encumbrances: $435,382.10 Source: INO Therapeutics/Ikari Role: Site Principal-Investigator Su Hasan

2. *2012-2013 Use of trio-based whole exome sequencing to identify the causes of sporadic syndromic intellectural disability: a pilot study with implications for the investigation for de novo Paediatric Disease Amount: $49,384.00 Source: Role: Principal Investigator M Innes

3. *2010-2013 CASPER-PCV (Calgary Area Streptococcus pneumoniae Epidemiology Research – Pneumococcal Conjugate Vaccine) Study: Continuation of Evaluation of Trends in Nasopharyngeal Colonization in Canada. Amount: $123,736.00 Source: Wyeth Pharmaceuticals (Grant-

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in-aid) Role: Primary Investigator Jd Kellner, Co-Investigator O vanderkooi *2011-2013 CASPER-PCV (Calgary Area Streptococcus pneumoniae Epidemiology Research-Pneumococcal Conjugate Vaccine) Study IV – Continuation of Surveillance and Analysis of Invasive Pneumococcal Disease (IPD) and Pneumococcal Related Disease (PRD) in Canada Amount: $649.146.00 Source: Pfizer Pharmaceuticals (Investigator Initiated Research) Role: Primary Investigator Jd Kellner, Co-Investigator O vanderkooi

4. *2011-2013 The Importance of International Travel in the Spread of Extended-Spectrum beta-Lactamase Producing E.Coli Amount: $75,000.00 Source: Merck Canada (Grant in Aid) Role: Co-Investigators O vanderkooi, S Kuhn

5. *2010-2015 PITT0908: Clinical Trial of Coenzyme Q10 and Lisinopril in Muscular Dystrophies Amount Direct (during 2012-13): $4,500 Total: $25,000 Source: US Department of Defense and

Cooperative International Neuromuscular Research Group Role: Local Primary Investigator JK Mah, Site Primary Investigator P Clemens, University of Pittsburgh

6. *2010-2012 An open-label study to assess the safety, tolerability and efficacy of canakinumab (ACZ885) in patients aged 4 years or older diagnosed with cryopyrin-associated periodic syndromes in Canada Amount: $13,299 Source: Novartis Role: Site Primary Investigator P Miettunen, Co Investigators H Schmeling, N Johnson

7. *2010-2012 A randomized, double-blind, placebo controlled, withdrawal study of flare prevention of canakinumab (ACZ885) in patients with Systemic Juvenile Idiopathic Arthritis (SJIA) and active systemic manifestations Award: $ 6,310.00 Source: NovartisDetails: Protocol #CACZ885G2301 Role: Site Principal Investigator P Miettunen, Co-Investigators: H Schmeling, N Johnson

8. *2010-2012 An Open-Label Extension Study Of Canakinumab (ACZ885) In Patients With

Systemic Juvenile Idiopathic Arthritis (SJIA) And Active Systemic Manifestations. Amount total award: $4,450.00 Source: Novartis Details: Protocol # CACZ885G2301E1 Role: Site Principal Investigator P Miettunen, Co-Investigators: H Schmeling, N Johnson

9. *2010-2012 An Open-Label Study To Assess The Safety, Tolerability And Efficacy Of Canakinumab (ACZ885) In Patients Aged 4 Years Or Older Diagnosed With Cryopyrin-Associated Periodic Syndromes In Canada. Amount total: $13,299.00 Details: Protocol # CACZ885DCA01 Source: Novartis Role: Site Principal Investigator P Miettunen, Co-Investigators: H Schmeling, N Johnson

10. * 2010-2012 A Randomized, Double-Blind, Placebo Controlled, Single-Dose Study To Assess The Initial Efficacy Of Canakinumab (ACZ885) With Respect To The Adapted ACR Pediatric 30 Criteria In Patients With Systemic Juvenile Idiopathic Arthritis (SJIA) And Active Systemic Manifestations. Amount total: $6,403.00 Details: Protocol

#CACZ885G2305 Source: Novartis Role: Site Principal Investigator P Miettunen, Co-Investigators: H Schmeling, N Johnson

11. *2012-2014 Canadian Pediatric Society Surveillance study: Periodic fever syndromes Co-investigator for Canadian Pediatric Society’s Surveillance Program on Periodic Fevers. Amount total: $40,000 Source: Novartis Role: Principal investigator P Dancey, Memorial University, Co-Investigators: P Miettunen, H Schmeling, N Johnson Co-investigators Susanne benseler, MD, University of Toronto

12. *06/2009-06/2013 Pharmacogenetics Of Juvenile Idiopathic Arthritis – The Influence Of Single-Nucleotide Polymorphisms In Candidate Genes On The Efficacy And Toxicity Of Etanercept. Amount: $72,000 Source: Pfitzer (Wyeth) Germany Role: Primary Investigator H Schmeling, Co-Investigator P Miettunen

13. *2012-2014 A phase I pharmacokinetic and safety study of tocilizumab in sJIA patients less than 2 years old Amount: $22,013

Source: Hoffman-la Roche Role: Site Primary Investigator H Schmeling, Co investigators: P Miettunen, N Johnson

14. *2012-2013 Parental Burden of RSV Amount: $15,975.67 Source: Abbott International Role: Principal Investigator I Mitchell

15. *2004-2013 Canadian Study of Palivizumab Amount: $6,275,0000 Source: AbbVie, Canada Role: Principal Investigator I Mitchell, Co Investigators B Paes, K Lanctot

16. *1999-Ongoing RSV Prevention in Calgary Amount: $ 639,175.00 Source: AbbVie Canada Role: Principal Investigator I Mitchell

17. *2009-2013 Randomized double-blind, placebo controlled withdrawal trial to evaluate the efficacy and safety of tocilizumab in polyarticular juvenile idiopathic arthritis Amount: $137,442 Source: Hoffman-la Roche Role: Site Primary Investigator H Schmeling, Co investigators: P Miettunen, N Johnson

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18. *2011-2014 Pertussis Vaccine in Pregnancy Amount: $213,683.00 Source: Sanofi Pasteur Role: Site Primary Investigator O vanderkooi, S Kuhn, Jd Kellner Co- Investigator

19. *2007-2012 The Epidemiology of Pediatric Inflammatory Bowel Disease in the Western Region of North America (IBD Study) Amount balance: (3,667.44) General Classification: Grant General Operating Sponsor: Cedars-Sinai Medical Centre Role: Principal Investigator: wrobel I

20. *2008-Ongoing Adalimumab in Pediatric Subjects with Moderate to Severe Crohn’s Disease General Classification: Contract Clinical Trials Amount balance: $11,875.54 Source: Abbott Laboratories Role: Primary Investigator wrobel I

21. **2012-Present Infliximab IBD Influenza Vaccine Study: Effect of Influenza Vaccination Timing on Immune Response in Patients with Inflammatory Bowel Disease on Infliximab Amount: $107,006.40 Source: Janssen Inc.

Primary Investigator: debruyn J

22. **2012-Present Serum infliximab levels and pharmacokinetics following first infliximab dose for induction of remission in children with moderate to severely-active ulcerative Source: Future Leaders in IBD (Janssen Inc) & Prometheus Amount: $375,000.00 Role: Primary Investigator debruyn J

23. **2012-2013 Fetal Programming of Infant Stress Reactivity and Atopic Disease Amount: $35,000 Source: AllerGen Initiative Role: Primary Investigator giesbrecht, gF, Co-Investigators: Letourneau, N., Kozyrskyj Kaplan b, Field C, Manhane P, Wynne-Edwards K, Campbell T, Soares C

24. ** 2012-present A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination with Metformin IR or Metformin XR in Pediatric Patients with Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone Amount: $14 365.52 per patient Source: Bristol Myers

Squibb, Inc. Role: Site Primary Investigator J Ho, Co-Investigators d Pacaud, C. Huang, r. Perry

25. **2012-Present Human Heterologous Liver Cells for Infusion in Children with Urea Cycle Disorders (SELICA III) Amount: $166,000/patient Source: Cytonet Local Primary Investigator: aneal Khan, Co-investigator S Martin

26. **2013 Strategies to enhance stem cell mediated mitochondrial transfer: potential for the treatment of mitochondrial disease. Amount: $50,000 Source: MitoCanada Role: Primary Investigator: Shearer J; Co-Investigators: rho J, Martin S, Khan a

27. **2012-2015 An Open-Label Study for previously Treated Ataluren (PTC124) Patients with Nonsense Mutation Dystrophinopathy Amount: $2500 (during 2012-13): $2500 Total: $10,000 Source: PTC Therapeutics Role: Primary Local Investigator JK Mah

28. **2012-2013 RSV Prevention in Calgary Amount: $ 147,340

Source: AbbVie Canada Role: Principal investigator I Mitchell

29. **12/2012-03/201 A Phase IV study to evaluate decreased dose frequency in patients with systemic juvenile idiopathic arthritis (sJIA) who experience laboratory abnormalities during treatment with Tocilizumab Amount: $32,534

30. Source: Hoffman-la Roche Role: Site Primary Investigator H Schmeling

31. **2013-2015 A phase Ib, open-label, multicenter study to investigate the pharmacokinetics, pharmacodynamics, and safety of tocilizumab following subcutaneous administration to patients with systemic juvenile idiopathic arthritis. Amount: $56,954 Source: Hoffman-la Roche Role: Site Primary Investigator H Schmeling

32. **2012-2023 A Multi-center, Randomized Parallel Group, Placebo-Controlled Double-Blind Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of Belimumab, a Human Monoclonal Anti-BLyS

Antibody, Plus Standard Therapy in Pediatric Patients with Systemic Lupus Erythematosus (SLE) Amount: $335,870 Source: GlaxoSmithKline/HGS Role: Site Co Investigator H Schmeling

33. **2013-2015 A phase Ib, open-label, multi-center study to investigate the pharmacokinetics, pharmacodynamics, and safety of tocilizumab following subcutaneous administration to patients with polyarticular course juvenile idiopathic arthritis Amount: $49,194 Source: Hoffman-la Roche Role: Site Primary Investigator H Schmeling

**2012-2015 A multi-center, open-label study to assess the pharmacokinetics, safety, and efficacy of certolizumab pegol in children and adolescents with moderately to severely active polyarticular-course juvenile idiopathic arthritis Amount: $278,680 Source: UCB Biosciences Inc Role: Site Primary Investigator H Schmeling

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Peer-Reviewed Research Publications

1. Smyth D, Al Awad E, akierman a, Remington T, Barber D, vayalumkal J. Eosinophilic Pustular Folliculitis In A Premature Infant: Case Report And Literature Review.       Journal Of Neonatal-Perinatal Medicine 2012(5):179-182

2. Alshaikh B, Dersch Mills D, Taylor R, akierman ar, yusuf K. Extended Interval Dosing Of Gentamicin In Premature Neonates ≤ 28-Week Gestation. Acta Paediatr 2012 Nov; 101(11):1134-9.

3. Dersch-Mills D, Alshaikh B, akierman ar, yusuf K. Validation Of A Dosage Individualization Table For Extended Interval Gentamicin In Neonates.

4. Annals of Pharmacotherapy 2012 Jul-Aug; 46(7-8): 935-42.

5. amin HJ, Aziz K, Halamek L, beran T. Simulation-Based Learning Combined

with Debriefing: Trainers Satisfaction with a New Approach to Training the Trainers to Teach Neonatal Resuscitation. BMC Research Notes 2013; 6:251.

6. Li K, Thomas Ma, Haber rM. Ulerythema Ophryogenes: A Rarely Reported Cutaneous Manifestation Of Noonan Syndrome. Case Report And Review Of The Literature. Journal of Cutaneous Medicine and Surgery Med Surg. 2013 May-Jun;17(3):212-8

7. Myers KA, Thomas Ma, Wei XC and Scantlebury MH. Case Report: Cleidocranial Dysplasia In A Neonate With Apneas And Tonsillar Herniation. Journal of Pediatrics 2013 Jul; (Accepted)

8. Zucker M, Clarke M, vanWylick R, Bernstein S, Au H, Talarico S, McKassey K, Grimmer J, Baron T, Moddemann D, Hyman J, McConnell A, bannister S, Johnson N, Midgley J,

Lewis M, Forbes K, Lee J, Virji M, Aitkenson V et al. Canuc-paeds: Canadian Undergraduate Curriculum in Paediatrics developed by PUPDOC (thePaediatric Undergraduate Program Directors of Canada) http://canucpaeds.pbworks.com/w/page/54470748/canuc-paeds%20homepage

9. barlow KM. Characteristics Of Post-Traumatic Headaches In Children Following Mild Traumatic Brain Injury And Their Response To Treatment: A Prospective Cohort. Dev Med Child Neurol. 2013 Jul;55(7):636-41. Epub 2013 Apr 5.

10. Hamilton M , Genge A, Johnston M, Lam D, Mobach T, Marriott J, Steeves T, Donner E, Wysocki J, barlow K, Shevell M, Marrie RA, Casha S, Mackean G, Casselman L, Korngut L, Pringsheim , Jette N, "Patient Recruitment By Neurological Registries.", The Canadian Journal of

Neurological Sciences. 2013;40(4 Suppl 2)

11. barlow K. Weight Gain After Childhood Traumatic Brain Injury. Dev Med Child Neurol. 2012;54(7):583.

12. Macciocchi S, Seel RT, Warshowsky A, Thompson N, barlow K. Co-Occurring Traumatic Brain Injury And Acute Spinal Cord Injury Rehabilitation Outcomes. Arch Phys Med Rehabil. 2012;93(10):1788-94.

13. Girotto F, Scott L, Avchalumov Y, Harris J, Iannattone S, Drummond-Main C, Tobias R, bello-espinosa l, rho JM, Davidsen J, Teskey GC, Colicos MA. High Dose Folic Acid Supplementation Of Rats Alters Synaptic Transmission And Seizure Susceptibility In Offspring. Sci Rep. 2013;3:1465.

14. Hrabok M, Sherman EM, bello-espinosa L, Hader W. Memory And

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Health-Related Quality Of Life In Severe Pediatric Epilepsy. Pediatrics. 2013Feb;131(2):e525-32.

15. Verhey LH, Branson HM, Laughlin S, Shroff MM, benseler SM, Feldman BM, Streiner DL, Sled JG, Banwell B. Development of a Standardized MRI Scoring Tool for CNS Demyelination in Children. Am J Neuroradiol. 2013 Jun;34(6):1271-7.

16. Kuemmerle-Deschner JB, Wittkowski H, Tyrrell PN, Koetter I, Lohse P, Ummenhofer K, Rees F, Hansmann S, Koitschev A, Deuter C, Bialkowski A, Foell D, benseler SM. Treatment Of Muckle-Wells Syndrome: Analysis Of Two Il-1-Blocking Regimens. Arthritis Res Ther. 2013 May 29;15(3):R64.

17. Jones KC, benseler SM, Moharir M. Anti-NMDA Receptor Encephalitis. Neuroimaging Clin N Am. 2013 May;23(2):309-20..

18. Moharir M, Shroff M, benseler SM. Childhood Central Nervous System Vasculitis. Neuroimaging Clin N Am. 2013 May;23(2):293-308.

19. Lim LS, Lefebvre A, benseler SM, Silverman ED. Longterm Outcomes And Damage Accrual In Patients With Childhood Systemic

Lupus Erythematosus With Psychosis And Severe Cognitive Dysfunction. J Rheumatol. 2013 Apr;40(4):513-9.

20. Lim LSH, Lefebvre A, benseler SM, Peralta M, Silverman ED. Psychiatric Illness Of Systemic Lupus Erythematosus In Childhood: Spectrum Of Clinically Important Manifestations. J Rheumatol. 2013 Apr;40(4):506-12.

21. Kuemmerle-Deschner J, Koitchev A, Gramlich K, Hansmann S, Plontke S, Koitchev C, Koetter I, Angermair E, benseler SM. Hearing Loss In Muckle-Wells Syndrome. Arthritis Rheum. 2013 Mar;65(3):824-31.

22. Titulaer M, McCracken L, Gabilondo I, Armangué T, Glaser C, Iizuka T, Honig L, benseler SM, Kawachi I, Martinez-Hernandez E, Aguilar E, Gresa-Arribas N, Ryan-Florance N, Torrents A, Saiz A, Rosenfeld M, Balice-Gordon R, Graus F, Dalmau J. Treatment And Prognostic Factors For Long-Term Outcome In Patients With Anti-N-Methyl-D-Aspartate (Nmda) Receptor Encephalitis: A Cohort Study. Lancet Neurol. Lancet Neurol. 2013 Feb;12(2):157-65.

23. Hugle B, Haas JP, benseler SM. Treatment Preference In

Juvenile Idiopathic Arthritis – A Comparative Analysis In Two Health Care Systems. Pediatr Rheumatol Online J. 2013 Jan 15;11(1):3.

24. Moran CJ, Walters TD, Guo CH, Kugathasan S, Klein C, Turner D, Wolters VM, Bandsma RH, Mouzaki M, Zachos M; NEOPICS, Langer JC, Cutz E, benseler SM, Roifman CM, Silverberg MS, Griffiths AM, Snapper SB, Muise AM.IL-10R Polymorphisms Are Associated With Very-Early-Onset Ulcerative Colitis. Inflamm Bowel Dis. 2013 Jan;19(1):115-123.

25. Batthish M, Banwell B, Laughlin S, Halliday W, Peschken C, Paras E, benseler SM. Refractory Primary CNS Vasculitis of Childhood: Successful Treatment with Infliximab. The Journal of Rheumatology 2012 Nov;39(11):2227-9.

26. Gowdie P, Twilt M, benseler SM. Primary And Secondary Central Nervous System Vasculitis. Journal of Child Neurology 2012 Nov;27(11):1448-59.

27. Cellucci T, Tyrrell PN, Pullenayegum E, benseler SM.von Willebrand Factor Antigen--A Possible Biomarker Of Disease Activity In Childhood Central Nervous System Vasculitis?

Rheumatology (Oxford). 2012 Oct;51(10):1838-45.

28. Morishita K, Guzman J, Chira P, Zeft AS, Klein-Gitelman M, Uribe AG, Abramson L, Ballinger S, benseler SM, Campillo S, Eberhard A, Eichenfield A, Hashkes PJ, Hersh AO, Higgins G, Jerath R, Jung L, Kim S, Kingsbury DJ, Li SC, Lovell DJ, Mason T, McCurdy D, Muscal E, Nassi L, O’Neil KM, Onel K, Rabinovich E, Ramsey S, Reiff A, Rosenkranz M, Schikler K, Singer N, Spalding S, Stevens A, Wahezi D, Zemel L, Cabral DA. Do Adult Disease Severity Subclassifications Predict Use Of Cyclophosphamide In Children With Anca-Associated Vasculitis? An Analysis of ARChiVe Study Treatment Decisions. Journal of Rheumatology. 2012 Oct;39(10):2012-20.

29. Lim LS, benseler SM, Tyrrell PN, Harvey E, Herbert D, Charron M, Silverman ED. Predicting Longitudinal Trajectory Of Bone Mineral Density In Paediatric Systemic Lupus Erythematosus Patients. Ann Rheum Dis. 2012 Oct;71(10):1686-91.

30. Soon GS, Rodan LH, Laughlin S, Laxer RM, benseler SM, Silverman ED. reversible splenial lesion syndrome in

Pediatric Systemic Lupus Erythematosus. J Rheumatol. 2012 Aug;39(8): 1698-9.

31. Dolezalova P, Price-Kuehne FE, Ozen S, benseler SM, Cabral DA, Anton J, Brunner J, Cimaz R, O'Neil KM, Wallace CA, Wilkinson N, Eleftheriou D, Demirkaya E, Böhm M, Krol P, Luqmani RA, Brogan PA. Disease Activity Assessment In Childhood Vasculitis: Development And Preliminary Validation Of The Paediatric Vasculitis Activity Score (Pvas). Ann Rheum Dis. 2012 Oct 25.

32. Uribe AG, Huber AM, Kim S, O'Neil KM, Wahezi DM, Abramson L, Baszis K, benseler SM, Bowyer SL, Campillo S, Chira P, Hersh AO, Higgins GC, Eberhard A, Ede K, Imundo LF, Jung L, Kingsbury DJ, Klein-Gitelman M, Lawson EF, Li SC, Lovell DJ, Mason T, McCurdy D, Muscal E, Nassi L, Rabinovich E, Reiff A, Rosenkranz M, Schikler KN, Singer NG, Spalding S, Stevens AM, Cabral DA. Increased Sensitivity Of The European Medicines Agency Algorithm For Classification Of Childhood Granulomatosis With Polyangiitis.J Rheumatol. 2012 Aug:39(8):1687-97.

33. Koitschev A, Gramlich K,

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Hansmann S, benseler S, Plontke SK, Koitschev C, Koetter I, Kuemmerle-Deschner JB. Progressive Familial Hearing Loss In Muckle-Wells Syndrome. Acta Otolaryngol. 2012 Jul;132(7):756-62.

34. benseler S, Pohl D. Childhood Central Nervous System Vasculitis. Handb Clin Neurol. 2013;112:1065-78.

35. Pohl D, benseler S. Systemic Inflammatory And Autoimmune Disorders. Handb Clin Neurol. 2013;112:1243-52.

36. Lynch DC, Dyment DA, Huang L, Nikkel SM, Lacombe D, Campeau PM, Lee B, Bacino CA, Michaud JL, bernier FP. FORGE Canada Consortium, Parboosingh JS, Innes AM. Identification Of Novel Mutations Confirms Pde4d As A Major Gene Causing Acrodysostosis. Hum Mutat. 2012;34(4):667.

37. Letourneau N, giesbrecht gF, bernier FP, Joschko J. How Do Interactions Between Early Caregiving Environment and Genes Influence Health and Behavior? Biol Res Nurs. 2012 Oct 24. [Epub ahead of print]

38. Bouchard S, bernier F, Boivin É, Dumoulin S, Laforest M, Guitard T,

Robillard Monthuy-Blanc J, Renaud P. Empathy Toward Virtual Humans Depicting A Known Or Unknown Person Expressing Pain. Cyberpsychol Behav Soc Netw. 2013 Jan;16(1):61-71.

39. Kaplan BJ, Leung BM, Giesbrecht GF, Field CJ, bernier FP, Tough S, Cui X, Dewey D; APrON Study Team. Increasing The Quality Of Life From Womb To Grave: The Importance Of Pregnancy And Birth Cohorts. Appl Physiol Nutr Metab. 2013 Jan; 38(1):85-9.

40. Sawyer SL, dicke F, Kirton a, Rajapkse T, Rebeyka IM, McInnes B, Parboosingh JS, bernier FP. Longer Term Survival Of A Child With Autosomal Recessive Cutis Laxa Due To A Mutation In Fbln4. Am J Med Genet 2013 Mar 26. Epub ahead of print.

41. Sawyer S, dickie F, Kirton a, Parboosingh J,bernier FP. Longer Term Survival Of A Child With Autosomal Recessive Cutis Laxa Due To A Novel Fibulin 4 Mutation. Am J Med Genet 2013 May;161(5):1148-53.

42. MetcalfeA, Currie g, Johnson JA, bernier F, Lix LM, Lyon AW, Tough SC. Impact Of Observed Versus Hypothesized Service Utilization On The Incremental Cost Of First

Trimester Screening And Prenatal Diagnosis For Trisomy 21 In A Canadian Province. Prenat Diagn 2013;33(5):429-35.

43. Metcalfe A, Lix LM, Johnson JA, bernier F, Currie g, Lyon AW, Tough SC. Assessing the Impact of the Sogc Recommendations to Increase Access to Prenatal Screening on Overall Use of Health Resources in Pregnancy.. J Obstet Gynaecol Can 2013;35(5):444-53.

44. bjornson Cl, Johnson dw. Introduction to Clinical Answers: Croup. Evid.-Based Child Health 2012; 7: 883-885.

45. Paes B, Mitchell I, Li A, Lanctôt KL, CARESS investigators (Allen U, Bacheyie G, Bayliss A, bjornson C, Blayney M, Canakis AM, Canning R, Caouette G, Chang K, Chang L, Chiu A, DiGravio B, Doray JP, Dumas ME, Ho V, Hui C, Jagdis F, Lebel M, Lee D, Majaesic C, Margolis I, Mitchell M, O'Brien K, Ojah C, Papageorgiou A, Popovich J, Sankaran K, Simmons B, Stinson D, Bjornson C, Caouette G, Lebel M, Dumas ME, Hui C, Bayliss A, DiGravio B, Doray JP, Stinson D, Papageorgiou A, Mitchell M, Chiu A, Paes B, Canning R, Canakis AM, O'Brien

K, Chang K, Sankaran K, Ho V, Allen U, Chang L, Ojah C, Lee D, Majaesic C, Blayney M, Popovich J, Jagdis F, Margolis I, Osler W, Bacheyie G, Simmons B). A Comparative Study Of Respiratory Syncytial Virus (Rsv) Prophylaxis In Premature Infants Within The Canadian Registry Of Palivizumab (Caress). Eur J Clin Microbiol Infect Dis. 2012 Oct;31(10):2703-11. Epub 2012 May 1.

46. Lynch DC, Dyment DA, Huang L, Nikkel SM, Lacombe D, Campeau PM, Lee B, Bacino CA, Michaud JL, bernier FP; FORGE Canada Consortium, Parboosing JS, Innes aM. 2013. Identification Of Noel Mutations Confirms Pde4d As A Major Gene Causing Acrodysostosis. Hum Mutat.  34:97-102.

47. bray S, Arnold A, Iaria G, MacQueen G. Structural Connectivity Of Visuotopic Intra-Parietal Sulcus. NeuroImage 2013;82:137-45.

48. bray S, Hoeft F, Hong DS, Dunkin B, Reiss A. Aberrant Functional Network Recruitment Of Parietal Cortex In Turner Syndrome. Human Brain Mapping 2013; 34(12):3117-28.

49. Ludwick T, brenner Jl, Kyomuhangi T, Wotton KA, Kabakyenga JK. Poor

Retention Does Not Have To Be The Rule: Retention Of Volunteer Community Health Workers In Uganda Health Policy Plan. 2013 May 6. Epub ahead of print

50. buchhalter Jr. The Relationship Between Nocturnal Discharges And Language Dysfunction In Rolandic Epilepsy: Treat The Child, Not The Adage. Epilepsy Curr. 2012 Sep;12(5):192-3.

51. buchhalter J. Diagnostic Coding For Epilepsy. Continuum (Minneap Minn). Epilepsy 2013;19(3):806-12.

52. Morgan LA, Dvorchik I, Williams KL, Jarrar RG, buchhalter Jr. Parental Ranking Of Terms Describing Nonepileptic Events. Pediatr Neurol. 2013;48(5):378-82.

53. buchhalter J, Stang a. Commentary On ‘Propofol Versus Thiopental Sodium For The Treatment Of Refractory Status Epilepticus-Still No Answer. Evid. Based Child Health 8: 1509-1510 (2013)

54. Al-Hussaini A, butzner d. Therapeutic Applications of Octreotide in Pediatric Gastroenterology. Saudi J Gastroenterol. 18: 87-94, 2012.

55. Soon IS, butzner Jd,

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Department of paeDiatrics | annual report 2013122

Kaplan GG, deBruyn JC. Incidence and Prevalence of Eosinophilic Esophagitis in Children: Systemic Review and Meta-Analysis. J Pediatr Gastroenterol Nutr. 57: 72-80, 2013.

56. Sigalet DL, Kravarusic D, butzner d, Hartmann B, Holst JJ, Meddings J. A pilot study examining the relationship among Crohn disease activity, glucagon-like peptide-2 signalling and intestinal function in pediatric patients. Can J Gastroenterol. 27: 587-92, 2013.

57. Sigalet E, Donnon T, Cheng a, Cooke S, Robinson T, Bissett W, grant v. Development of a team performance scale to assess undergraduate health professionals. Acad Med 2013;88(7):989-96.

58. Lancsar E, Louviere J, Donaldson C, Currie g, Burgess L. Best worst discrete choice experiments in health: Methods and an application, Social Science & Medicine, Volume 76, January 2013, Pages 74-82.

59. Metcalfe A, Lix LM, Johnson J, bernier F, Currie g, Lyon AW, Tough SC. Assessing the impact of the SOGC recommendations to increase access to prenatal screening on overall

health resource utilization in pregnancy. J Obstet Gynaecol Can 2013; 35(5): 444-453.

60. Metcalfe A, Currie g, Johnson J, bernier F, Lix LM, Lyon AW, Tough SC. Impact of observed versus hypothesized service utilization on the incremental cost of first trimester screening and prenatal diagnosis in a Canadian province. Prenat Diagn 2013; 33(5): 429-35.

61. Cheng a, Hunt EA, Donoghue A, Nelson-McMillan K, Nishisaki A, LeFlore J, Eppich W, Moyer M, Brett-Fleegler M, Kleinman M, Anderson J, Adler M, Braga M, Kost S, Stryjewski G, Min S, Podraza J, Lopreiato J, Fiedor Hamilton M, Stone K, Reid J, Hopkins J, Manos J, Duff J, Richard M, Nadkarni V, for the EXPRESS Investigators. Examining Pediatric Resuscitation Education Using Simulation and Scripting (EXPRESS): A Multicenter, Randomized-Controlled Trial. JAMA Pediatrics, epub ahead of print, April 22, 2013. PI

62. Duff J, Cheng a, Bahry L, Hopkins J, Richard M, Schexnayder S, Carbonaro M. Development and Validation of a Multiple Choice Examination Assessing Cognitive and

Behavioural Knowledge of Pediatric Resuscitation: A Report from the EXPRESS Pediatric Research Collaborative. Resuscitation, July 25, 2012 epub ahead of print.

63. Hung G, Bialy L, Cheng a. Pediatric Emergency Medicine Fellows Education Day: Addressing CanMEDS Objectives in a National Forum. Peds Child Health. 2012. 17(10):544-548. SI

64. Cheng a, Rodgers D, Van Der Jagt E, Eppich W, O’Donnell J for the American Heart Association Pediatric Subcommittee. Evolution of the Pediatric Advanced Life Support Course: Enhanced Learning with a New Debriefing Tool and Web-based Module for Pedaitric Advanced Life Support Instructors. Pediatric Critical Care Medicine. 2012; 13(5): 589-595. Pa

65. Grant E, Grant VJ, Bhanji F, Duff J, Cheng a, Lockyer J. The Development and Assessment of an Evaluation Tool for Pediatric Resident Competence in Leading Simulated Pediatric Resuscitations. Resuscitation. 2012; 83(7):887-893. C

66. Qayumi K, Donn S, Zheng B, Young L, Dutton J, Adamack M, Bowles R, Cheng a. British Columbia Interprofessional

Model for Simulation-Based Education in Healthcare – A Network of Simulation Sites. Simulation in Healthcare. 2012; 7:295-307. SI

67. Brett-Fleegler M, Rudolph J, Eppich W, Fleegler E, Cheng a, Simon R. Debriefing Assessment for Simulation in Healthcare (DASH) : Development and Psychometric Properties. Simulation in Healthcare. 2012; 7:288-294. C

68. Bretholz A, Doan Q, Lauder G, Cheng a. A Pre and Post Survey of a Web and Simulation-Based Course of Ultrasound-Guided Nerve Blocks for Pediatric Emergency Medicine. Pediatric Emergency Care. 2012; 28:506-509. SI

69. Cheng a, Donoghue A, Gilfoyle E, Eppich W. Simulation-based crisis resource management training for pediatric critical care medicine: A review for instructors. Ped Crit Care Med. 2012. 13(2):197-203. Pa

70. Ortiz-Alvarez O, Mikrogianakis M, Cheng a et al. Management of the Pediatric Patient with an Acute Asthma Exacerbation. Pediatr Child Health. 2012. 17(5):251-256. C (National Guideline)

71. Sam J, Pierse M, Al-

Qahtani Q, Cheng a. Implementation and Evaluation of a Simulation Curriculum for Pediatric Residency Programs including Just in Time In-Situ Mock Codes. Pediatrics and Child Health. Pediatr Child Health. 2012, 17(1):1-5. SI

72. Soon Is, debruyn JC, wrobel I. Immunization History of Children with Inflammatory Bowel Disease. Can J Gastroenterol. 2013 Apr; 27(4): 213-6

73. debruyn JC, Hilsden R, Fonseca K, Russell ML, Kaplan GG, vanderkooi O, Wrobel I. Immunogenicity and Safety of Influenza Vaccination in Children with Inflammatory Bowel Disease. Inflammatory Bowel Diseases 2012;18(1):25-33.

74. Charles, E., Thomas, D.S., dewey d., Davey, M., Ngallaba, S.E., & Konje E. (January 2013). A cross-sectional survey on knowledge and perceptions of health risks associated with arsenic and mercury contamination from artisanal gold mining in Tanzania, BMC Public Health, 13, 74.

75. Ray, M., dewey. d., Kooistra, L., & Welsh, T.N. (June 2013). The relationship between the motor system activation during action observation

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and adaptation in the motor system following repeated action observation. Human Movement Science, 32, 400-411.

76. Kuczynski A, Crawford S, Bodell L, dewey d, barlow KM. Characteristics of post-traumatic headaches in children following mild traumatic brain injury and their response to treatment: a prospective cohort. Dev Med Child Neurol. 2013;55(7):636-41.

77. Ouellette-Kuntz H, Coo H, Lam M, Breitenbach MM, Hennessey PE, Jackman PD, Lewis ME, dewey d, bernier FP, Chung AM."The Changing Prevalence of Autism in Three Regions of Canada." [In Eng]. J Autism Dev Disord (Jun 16 2013) 23771514.

78. SL, dicke F, Kirton a, Rajapkse T, Rebeyka IM, McInnes B, Parboosingh JS, bernier FP. llevterm survival of a child with autosomal recessive cutislaxa due to a mutation in FBLN4. Am J Med Genet A. 2013;161A(5):1148-53.

79. Meeting the Health Care Needs of Street Involved Youth. april S elliott; Canadian Paediatric Society, Adolescent Health Committee . Paediatr Child Health 2013;18(6):317-21

80. Myers KA, Payne ET, esser MJ, Kirton a, Howard JJ. Thoracic myelopathy secondary to seizure following scoliosis surgery. J Child Neurol. 2012;27(7):914-6.

81. Gamble C, gamble J, Ali S, Wright B, Seal R. Bispectral Analysis During Procedural Sedation in the Pediatric Emergency Department. Pediatric Emergency Care. 2012 Oct;28(10):1003-1008.

82. giesbrecht g, Letournaeau N, Campbell T, Kaplan B J & the APrON Study Team (Dec 2012). Affective experience in ecologically relevant contexts is dynamic, and not progressively attenuated. Archives of Women’s Mental Health. 15(6):481-485

83. giesbrecht gF, Granger D, Campbell T, Kaplan bJ & the APrON Study Team (March 2013). Salivary alpha-amylase during pregnancy: Diurnal course and associations with obstetric history, maternal characteristics and mood. Developmental Psychobiology. 55, 156-167

84. Sigalet E, Donnon T, grant v. Undergraduate students' perceptions of and attitudes toward a simulation-based interprofessional curriculum: The KidSIM ATTITUDES questionnaire. Simul Healthc 2012;7(6):353-8.

Epub 2012 Aug 16.

85. grisaru S, Watson-Jarvis K, McKenna C, Ho J, Harder J, Trussell b. Development of a Simple Tool for Diagnosis and Initial Approach to Hypertension and Pre-hypertension in Children and Youth. Open Journal of Pediatrics. June 2012; 2(2):106-110

86. Decloe M, emery Ca, Hagel be, Meeuwisse WH. Injury rates, types, mechanisms and risk factors of injury in female youth ice hockey. British Journal of Sports Medicine. 2014;48(1):51-6. Epub 2013 Feb 27.

87. Romanow NTR, Hagel be, Nguyen M, Embree T, Rowe BH. Mountain bike terrain park injuries: an emerging cause of morbidity. International Journal of Injury Control and Safety Promotion. 2012 Dec 18. [Epub ahead of print]

88. Morrongiello BA, Sandomierski M, Hagel be, Schwebel DC. Are parents just treading water? The impact of participation in swim lessons on parents’ judgments of children’s drowning risk, swimming ability, and supervision needs. Accident Analysis & Prevention 2013; 50:1169-75.

89. Blake T, Hagel be, emery

Ca. Sport Medicine Journal Club: “Does Intentional or Unintentional Contact in Youth Ice Hockey Result in More Injuries?” [Commentary] Clinical Journal of Sport Medicine 2012;22(4): 377–378.

90. Davison K, Kaplan bJ . Nutrient- and non-nutrient-based natural health product (NHP) use in adults with mood disorders: prevalence, characteristics and potential for exposure to adverse events. BMC Complementary and Alternative Medicine 2013;13(1):80.

91. Kaplan bJ, geisbrecht gF, Leung BMY, Field CJ, dewey d, Bell RC, Manca DP, O’Beirne M, Johnston dw, Pop VJ, Singhal N, Gagnon L, bernier FP, Eliasziw M, McCargar LJ, Kooistra L, Farmer A, Cantell M, Goonewardene L, Casey LM, letourneau N, Martin JW. (July 17 2012). The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study: Rationale and Methods. Maternal and Child Nutrition Matern Child Nutr. 2014 Jan;10(1):44-60. Epub 2012 Jul 17.

92. giesbrecht g, Campbell T, letourneau N, Kaplan b, and the APrON Study Team (April 2013). Advancing gestation does not attenuate biobehavioural coherence

between psychological distress and cortisol. Biological Psychology 93: 45– 51.

93. Miller M, giesbrecht gF, McInerney J, Kerns K, & Müller, U. (2012). A latent variable approach to determining the structure of executive function in preschool children. Journal of Cognition and Development, 13, 395-423.

94. Chamorro-Viña C, guilcher gM, Khan FM, Mazil K, Schulte F, Wurz A, Williamson T, Reimer RA, Culos-Reed SN. EXERCISE in pediatric autologous stem cell transplant patients: a randomized controlled trial protocol. BMC Cancer Sep 10;12:401. 2012.

95. Sigalet E, Donnon T, grant v. Undergraduate Students' Perceptions of and Attitudes Toward a Simulation-Based Interprofessional Curriculum: The KidSIM ATTITUDES Questionnaire. Simulation in Healthcare 2012;7(6):353-8.

96. grant eC, grant vJ, Bhanji F, Duff JP, Cheng a, Lockyer JM. The development and assessment of an evaluation tool for pediatric resident competence in leading simulated pediatric resuscitations. Resuscitation 2012;83(7):887-93.

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97. grueger b and Canadian Paediatric Society Community Paediatrics Committee. Weaning from the breast.

98. Pediatrics & Child Health 2013;18(4):210-11.

99. gross Ml, Tenenbein M, Sellers EAC. Severe vitamin D deficiency in 6 Canadian First Nation formula-fed infants. Int J Circumpolar Health 2013;72: 20244

100. Harabor a, Fruitman d. Comparison between a suprasternal or high parasternal approach and an abdominal approach for measuring superior vena cava Doppler velocity in neonates. J Ultrasound Med. 2012 Dec; 31(12):1901-7.

101. Hasan Su, yusuf K. Rat homologues to the human post neonatal period: Modes for vulnerability to the sudden infant death syndrome. Pediatr Pulmonol 2012 July; 47:731.

102. Nair V, Hasan Su, Romanchuk K, Al Awad E, Mansoor A, yusuf K. Bilateral Cataracts Associated with Glucose-6-Phosphate Dehydrogenase Deficiency. J Perinatol, 2013 Jul; 33(7):574-575.

103. M. van Manen, l. Hendson, M Wiley, M. Evans, S. Taghaddos, I. Dinu. Early childhood outcomes of infants born with gastroschisis. J Ped Surg 2013;48:1682-1687.

104. Pepper D, Rempel G, Austin W, Ceci C, Hendson l. More than Information: A Qualitative Study of Parents' Perspectives on Neonatal Intensive Care at the Extremes of Prematurity. Advances in Neonatal Care 2012;12: 303-309.

105. Carney JA, Ho J, Kitsuda K, Stratakis CA, Young, WF. Massive neonatal adrenal enlargement due to cytomegaly, persistence of the transient cortex, and hyperplasia of the permanent cortex: Findings in Cushing Syndrome associated with hemihypertrophy. American Journal of Surgical Pathology. 2012;36(10):1452-1463.

106. Akierman S, Skappak C, Girgis R, Ho J. Turner Syndrome and apparent absent uterus: case report and review of literature. Journal of Paediatric Endocrinology and Metabolism February 2013; 26(5-6):587-589.

107. Nelson D, Ho J., Pacaud d., Stephure d. Virilization in

Two Pre-pubertal Children Exposed to Topical Androgen. Journal of Paediatric Endocrinology and Metabolism 2013 May 24:1-5. [Epub ahead of print]

108. Mameli C, Scaramuzza AE, Ho J, Cardona-Hernandez R, Suarez-Ortega L, Zuccotti G. A 7-year follow-up retrospective, international, multicenter study of insulin pump therapy in children and adolescents with type 1 diabetes. Acta Diabetologica 2013 May 17. [Epub ahead of print]

109. Huang C. Wild type offspring of heterozygous prolactin receptor null female mice have maladaptive beta-cell responses during pregnancy. Journal of Physiology 2013; 591 (Pt5): 1325-38.

110. Wiltshire KM, Hegele RA, Innes aM, Brownell KW. Homozygous Lamin A/C familial lipodystrophy R482Q mutation in autosomal recessive Emery Dreifuss Muscular Dystrophy. Neuromuscul Disord. 2013;23(3):265-8.

111. Beaulieu CL, Huang L, Innes, aM, Akimenko MA, Puffenberger EG, Schwartz C, Jerry P, Ober C, Hegele RA, Mcleod dr,

Schwartzentruber J, FORGE Canada Consortium, Majewski J, Bulman DE, Parboosingh JS, Boycott KM. 2013. Intellectual Disability Associated with a Homozygous Missense Mutation in THOC6. Orphanet J Rare Dis. 2013 Apr 26;8(1):62. [Epub ahead of print]

112. Bögershausen N, Shahrzad N, Chong JX, von Kleist-Retzow J-C, Stanga D, Li Y, Bernier FP, Loucks CM, Wirth R, Puffenberger EG, Hegele R, Schreml J, Lapointe G, Keupp K,, Brett CL, Anderson R, Hahn A,, Innes aM, Suchowersky O, Mets MB, Nürnberg G, McLeod DR, Thiele H, Waggoner D, Altmüller J, Boycott KM, Schoser B, Nürnberg P, Ober C, Heller R, Parboosingh JS, Wollnik B, Sacher M, Lamont RE 2013.  Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with infantile hyperkinetic movements and intellectual disability.  Am. J. Hum. Genet. 93:181-90.

113. Dyment DA, Smith AC, Alcantara D, Schwartzentruber J, Basel-Vanagaite L, Curry CJ, Temple IK, Reardon W, Mansour S, Haq MR, Gilbert R, Lehmann OJ, Vanstone MR, Beaulieu CL, FORGE

Canada Consortium, Majewski J, Bulman DE, O’Driscoll M, Boycott KM, Innes aM. 2013. Mutations in PIK3R1 Cause SHORT Syndrome. Am J Hum Genet 93: 158-66.

114. Doherty D, Chudley AE, Coghlan G, Ishak GE, Innes aM, Lemire EG, Rogers RC, Mhanni AA, Phelps IG, Jones SJ, Zhan SH, Fejes AP, Shahin H, Kanaan M, Akay H, Tekin M; FORGE Canada Consortium, Triggs-Raine B, Zelinski T. GPSM2 mutations cause the brain malformations and hearing loss in Chudley-McCullough syndrome. Am J Hum Genet. 2012 Jun 8;90(6):1088-93. Epub 2012 May 10. Erratum in: Am J Hum Genet. 2012 Jul 13;91(1):209. PubMed PMID: 22578326; PubMed Central PMCID:PMC3370271.

115. Bettinger JA, Scheifele DW, Le Saux N, Halperin SA, Vaudry W, Tsang R; Members of Canadian Immunization Monitoring Program, Active (IMPACT). (Jadavji, T Member) The disease burden of invasive meningococcal serogroup B disease in Canada. Pediatr Infect Dis J. 2013 Jan;32(1):e20-5.

116. Bettinger JA, Scheifele DW, Halperin SA, Vaudry W, Findlow J, Borrow R, Medini D, Tsang R;

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For the members of the Canadian Immunization Monitoring Program, Active (IMPACT). (Jadavji, T Member). Diversity of Canadian meningococcal serogroup B isolates and estimated coverage by an investigational meningococcal serogroup B vaccine (4CMenB). Vaccine. 12 April 2013.

117. Coyle D, Coyle K, Bettinger JA, Halperin SA, Vaudry W, Scheifele DW, Le Saux N. Members of Canadian Immunization Monitoring Program, Active (IMPACT) (Jadavji, T; vanderkooi, Og - Members) Cost effectiveness of infant vaccination for rotavirus in Canada. Canadian Journal of Infectious Diseases & Medical Microbiology 2012; 23(2): 71-77

118. Forbes JC, Alimenti AM, Singer J, Brophy JC, Bitnun A, Samson LM, Money DM, Lee TC, Lapointe ND, Read SE; Canadian Pediatric AIDS Research Group (CPARG). Collaborators: A AM, B A, Bortolussi B, Boucher F, B JC, Bullard J, Cohen J, Cooper R, Ellis M, Embree J, Forbes J, Hanley B, Jadavji T, Karatzios C, Lamarre V, L ND, Moore D, Onyett H, R SE, S LM, Sandre R, Siegel S, Smaill F, Sobol I, Sweet L, Tan

B, Vaudry W, Young M. A national review of vertical HIV transmission. AIDS. 2012 Mar 27;26(6):757-63.

119. McDermid A, Le Saux N, Grudeski E, Bettinger JA, Manguiat K, Halperin SA, Macdonald L, Déry P, Embree J, Vaudry W, Booth TF; Members of the Canadian Immunization Monitoring Program, Active. Collaborators: Morris R, Halperin S, Déry P, Moore D, Lebel M, Le Saux N, Tran D, Embree J, Tan B, Jadavji T, Vaudry W, Sauvé L. Molecular characterization of rotavirus isolates from select Canadian pediatric hospitals. BMC Infect Dis. 2012 Nov 15;12:306.

120. Top KA, Constantinescu CM, Lafleche J, Bettinger JA, Scheifele DW, Vaudry W, Halperin SA, Law BJ, (IMPACT). (Jadavji, T Member).. Applicability of the Brighton Collaboration Case Definition for seizure after immunization in active and passive surveillance in Canada. Vaccine. 2013;31(48):5700-5.

121. Tran D, Vaudry W, Moore DL, Bettinger JA, Halperin SA, Scheifele DW, Aziz S; IMPACT investigators. Collaborators: Morris R, Halperin S, Déry P, Moore D, Lebel M, Saux N, Tran D, Embree J, Tan B, Jadavji

T, Vaudry W, Sauvé L. Comparison of children hospitalized with seasonal versus pandemic influenza A, 2004-2009. Pediatrics. 2012 Sep;130(3): 397-406.

122. Manca DP, O’Beirne M, Lightbody T, Johnston dw, Dymianiw D-L, Nastalska K, Anis L, Loehr S, Gilbert A, Kaplan bJ, and the APrON Study Team (March 2013). The most effective strategy for recruiting a pregnancy cohort: A tale of two cities. BMC Pregnancy and Childbirth, 13:75.

123. Cellot S, Johnston d, Dix D, Ethier MC, Gillmeister B, Mitchell D, Yanofsky R, lewis v, Portwine C, Price V, Zelcer S, Silva M, Bowes L, Michon B, Stobart K, Brossard J, Beyene J, Sung L. Infections in pediatric acute promyelocytic leukemia: from the canadian infections in acute myeloid leukemia research group. BMC Cancer Jun 4;13(1):276. 2013.

124. Rodway M, Vance A, Watters A, Lee H, Bos E, Kaplan BJ (2012 Nov 9), Efficacy and cost of micronutrient treatment of childhood psychosis. BMJ Case Reports 2012 Nov 9; 2012.

125. Kaplan bJ, Leung BM, giesbrecht gF, Field CJ, bernier FP, Tough S, Cui X, dewey d, and the APrON Study Team (Jan 2013). Increasing the quality of life from womb to grave: The importance of pregnancy and birth cohorts. Appl Physiol Nutr Metab, 38(1):85-89.

126. Rucklidge JJ, Kaplan bJ (Jan 2013). Broad-spectrum micronutrient formulas for the treatment of psychiatric symptoms: A systematic review. Expert Reviews in Neurotherapeutics, 13(1):49-73.

127. Leung BMY, Kaplan bJ, Field CJ, Tough S, Eliasziw M, Gomez MF, McCargar LJ, Gagnon L, and the APrON Study Team (Jan 2013). Prenatal micronutrient supplementation and postpartum depressive symptoms in a pregnancy cohort. BMC Pregnancy and Childbirth,13:2.

128. Field LL, Shumansky K, Ryan J, Truong D, Swiergala E, Kaplan bJ. (Feb 2013). Dense-map genome scan for dyslexia confirms loci at 4q13, 16p12, 17q22; suggests novel locus at 7q36. Genes, Brain and Behavior. 12(1):56-69.

129. Tran C, Gagnon F, Wigg KG, Feng Y, Gomez L, Cate-Carter TD, Kerr EN, Field

LL, Kaplan bJ, Lovett MW, Barr CL (March 2013)  A Family-Based Association Analysis and Meta-Analysis of the Reading Disabilities Candidate Gene DYX1C1.  American Journal of Medical Genetics (Neuropsychiatric Genetics), 162B:146–156.

130. Leung BM, Kaplan bJ, Field CJ, Tough S, Eliasziw M, Gomez MF, McCargar LJ, Gagnon L, APrON Study Team. Prenatal micronutrient supplementation and postpartum depressive symptoms in a pregnancy cohort. BMC Pregnancy Childbirth. 2013 Jan; 13:2.

131. Bettinger JA, Scheifele DW, Halperin SA, Kellner Jd, vanderkooi Og, Schryvers A, DeSerres G, Alcantara J. Evaluation of Meningococcal Serogroup C Conjugate Vaccine Programs in Canadian Children: Interim Analysis. Vaccine 2012 ;30: 4023-27.

132. Daneman D, Kellner Jd. Navigating the Stages of an Academic Career for Pediatricians. Paediatrics & Child Health 2012 June/July;17(6):301-3.

133. VanderPluym C, Tawfik G, Hervas-Malo M, Lacaze-Masmonteil T, Kellner Jd, Robinson

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J. Empiric Therapy of Possible Neonatal Herpes Simplex Virus Infection. Journal of Maternal-Fetal and Neonatal Medicine 2012;25(8):1278-82.

134. Yam KK, Gupta J, Brewer A, Scheifele DW, Halperin S, Ward BJ; Public Health Agency of Canada/Canadian Institute of Health Research, Influenza Research Network (PCIRN) Rapid Trial Study 3 (RT-03) Investigators (Kellner Jd, member). Unusual Patterns of IgG Avidity in Some Young Children Following Two Doses of the Adjuvanted Pandemic H1N1 (2009) Influenza Virus Vaccine. Clinical and Vaccine Immunology. 2013;20(4):459-67.

135. Kirk vg, Currie g, dewey d, Howlett a, lemieux l, Prince T.Innovation in Physician Recruitment & Wellness: A Pilot Orientation Program. J Pediatr 2013 162(4) 664-5 (supplement 665e1-665e2)

136. Kirton a, Crone M, benseler S, Mineyko A, Armstrong D, Wade A, Sebire G, Crous-Tsanaclis AM, Deveber G. Fibromuscular dysplasia and childhood stroke. Brain. 2013 Jun;136(Pt 6):1846-56.

137. Kirton a. Predicting developmental plasticity after perinatal stroke. Dev Med Child Neurol. 2013;55(8):681-2.

138. Kirton a. Modeling developmental plasticity after perinatal stroke: defining central therapeutic targets in cerebral palsy. Pediatr Neurol. 2013;48(2):81-94.

139. Kirton a. Can noninvasive brain stimulation measure and modulate developmental plasticity to improve function in stroke-induced cerebral palsy? Semin Pediatr Neurol. 2013;20(2):116-26.

140. Rajapakse T, Kirton a. Non-invasive brain stimulation in children: applications and future directions. . Transl Neurosci. 2013;4(2).

141. Tuor UI, Qiao M, Morgunov M, Fullerton E, Foniok T, Kirton a. Magnetization transfer and diffusion imaging of acute axonal damage in the cerebral peduncle following hypoxia-ischemia in neonatal rats. Pediatr Res. 2013;73(3):325-31.

142. Tan MA, Miller E, Shroff MM, Deveber GA, Kirton a. Alleviation of neonatal sinovenous compression to enhance cerebral venous blood flow. J Child Neurol. 2013;28(5):583-8.

143. Yang JF, Livingstone D, Brunton K, Kim D, Lopetinsky B, Roy F, Zewdie E, Patrick SK, Andersen J, Kirton a, Watt JM, Yager J, Gorassini M. Training to enhance walking in children with cerebral palsy: are we missing the window of opportunity? Semin Pediatr Neurol. 2013;20(2):106-15.

144. Kirton a, Holland M, Sebire G, Armstrong D, Hawkins C, Wade A, deVeber G. Childhood stroke and fibromuscular dysplasia. Brain 2013;136:1846-56. epub May 28.

145. Kirton a. Modeling developmental plasticity after perinatal stroke: Defining central therapeutic targets in cerebral palsy. Ped Neurol 2013;48(2):81-94.

146. Rajapakse T, Kirton a. Emerging applications of non-invasive brain stimulation in children. Translational Neurosci 2013;4(2):217-233.

147. Tuor UI, Qiao M, Morgunov M, Fullerton E, Kirton a. Magnetization transfer imaging of acute axonal degeneration following unilateral cerebral hypoxia-ischemia in neonatal rats. Ped Res 2013; 73(3):325-31. Epub 2012 Nov 30.

148. Tan M, deVeber G, Miller E, Shroff M, Kirton a.

Alleviation of neonatal cerebral venous obstruction with a custom-designed pillow. J Child Neurol 2013; 28(5):583-8. epub 2012 July 17.

149. Schechter T, Kirton a, Laughlin S, Pontigon A, Finkelstein Y, MacGregor D, Chan A, deVeber G, Brandao L. Safety of anticoagulants in children with arterial ischemic stroke. Blood 2012; 119(4):949-56, epub Dec 7

150. Kirton a, Crone M, Benseler S, Mineyko a, Armstrong D, wade a, Sebire G, Crous-Tsanaclis AM, deVeber G.Fibromuscular Dysplasia and Childhood Stroke. Brain. 2013 Jun;136(Pt 6):1846-56.

151. Picard D, Miller S, Hawkins CE, Bouffet E, Rogers HA, Chan TS, Kim SK, Ra YS, Fangusaro J, Korshunov A, Toledano H, Nakamura H, Hayden JT, Chan J, lafay-Cousin l, Hu P, Fan X, Muraszko KM, Pomeroy SL, Lau CC, Ng HK, Jones C, Van Meter T, Clifford SC, Eberhart C, Gajjar A, Pfister SM, Grundy RG, Huang A. Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis. Lancet Oncol Aug;13(8):838-48. 2012.

152. Chaubey V, Davis J, Warren R, Parkins M, Louie M, Gregson D, Sabuda D, Kuhn S. Fever, headache, fatigue, and chancre in a traveler returning from Tanzania. Can J Infect Dis Med Microbiol 2012 Fall;23(3):108-9.

153. Johannes C, Kuhn S, lemay M, vanderkooi Og. A 5-year-old boy with fever after a trip to Venezuela (Salmonella Poona Case Report). Pediatrics and Child Health 2013;18(4):197-8.

154. Singh G, Wei XC, Hader W, Chan JA, Bouffet E, lafay-Cousin l. Sustained response to weekly vinblastine in 2 children with pilomyxoid astrocytoma associated with diencephalic syndrome. J Pediatr Hematol Oncol Mar;35(2):e53-6. 2013.

155. lafay-Cousin L, Purdy E, Huang A, Cushing SL, Papaioannou V, Nettel-aguirre a, Bouffet E. Early cisplatin induced ototoxicity profile may predict the need for hearing support in children with medulloblastoma. Pediatr Blood Cancer. 2013 Feb;60(2):287-92.

156. lafay-Cousin L, Hader W, Wei X, Nordal R, Strother d, Hawkins C, Chan J. Post-chemotherapy

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maturation in supratentorial primitive neuroectodermal tumors. Brain Pathol. 2013 Aug 30. [Epub ahead of print]

157. Singh G, Wei XC, Hader W, Chan JA, Bouffet E, lafay-Cousin L. J Sustained response to weekly vinblastine in 2 children with pilomyxoid astrocytoma associated with diencephalic syndrome. Pediatr Hematol Oncol. 2013 Mar;35(2):e53-6.

158. Branson LJ, latter J, Currie g, Nettel-aguirre a, Embree T, Hagel be. The effect of surfacing and season on playground injury rates. Paediatrics & Child Health 2012;17(9) 485-489.

159. Abdelfatah N, Merner N, Houston J, Benteau T, Griffin A, Doucette L, Stockley T, lauzon Jl, Young TL. (2013) A novel deletion in SMPX causes a rare form of X-linked progressive hearing loss in two families due to a founder effect. Hum Mut Jan;34(1):66-9.

160. Richer J, Nelson TN, Evans J, Armstrong L, lauzon J, McGillivray B. (2012) CCMG statement on gene patents. Clin Genet Nov;82(5):405-7. White J, Brownell K, lemay JF, and Lockyer JM. "What

Do They Want Me To Say?" The hidden curriculum at work in the medical school selection process: a qualitative study. BMC Med Educ 2012;12:17.

161. lemieux l. An approach to teaching interdisciplinary health care to pre-clerkship medical students. Hospital Pediatrics. 2012; 2(3): 179-181.

162. Hospital Pediatrics 2012;2(3):179 -181.

163. Hoy NY, leung aK, Metelitsa AI, Adams S. New concepts in median nail dystrophy, onychomycosis and hand-foot-and-mouth disease nail pathology. Dermatology 2012; 2012;68163.

164. Hon KL, leung aK. Neonatal lupus erythematosus. Autoimmune Diseases 2012;2012: 301274.

165. leung aK, Sauve rS, Marchand V. The ‘picky eater’: the toddler or preschooler who does not eat. Paediatrics and Child Health 2012;17:455-457.

166. leung aK, Hon KL. Seasonal allergic rhinitis. Recent Patents on Inflammation & Allergy Drug Discovery 2013;7:187-201.

167. Hon KL, leung aK,

Barankin B. Barrier repair therapy in atopic dermatitis: an overview. American Journal of Clinical Dermatology 2013;14:389-399.

168. leung aK, Wong AS. Localized acquired hypertrichosis associated with the application of a splint. Case Reports in Pediatrics 2012;2012:592092.

169. leung aK, Ng J. Generalized lichen nitidus in identical twins. Case Reports in Dermatological Medicine 2012;2012:982084.

170. Hon KL, leung aK. Chlamydial pneumonitis: a creepy neonatal disease. Case Reports in Pediatrics 2013;2013:549649.

171. leung aK, Barankin B. Physiological striae atrophicae of adolescence with involvement of the upper back. Case Reports in Pediatrics 2013;2013:386094.

172. Hon KL, Li J, Cheng C, leung aK. Septicemia in a neonate following therapeutic hypothermia: the literature review of evidence. Case Reports in Pediatrics 2013;2013:514232.

173. Hon KL, Luk DC, leung

aK. Cupping therapy may be harmful for eczema: a Pubmed search. Case Reports in Pediatrics 2013;2013:605829.

174. Hon KL, Cheng J, Chow CM, Cheung HM, Cheung KL, Tam YH, leung aK. Complications of bezoar in children: What is new? Case Reports in Pediatrics 2013;2013:523569.

175. Ayas M, Saber W, Davies SM, Harris RE, Hale GA, Socie G, LeRademacher J, Thakar M, Deeg HJ, Al-Seraihy A, Battiwalla, M, Camitta BM, Olsson R, Bajwa RS, Bonfim CM, Pasquini R, Macmillan ML, George B, Copelan EA, Wirk B, Al Jefri A, Fasth AL, Guinan EC, Horn BN, lewis va, Slavin S, Stepensky P, Bierings M, Gale RP. Allogeneic hematopoietic cell transplantation for fanconi anemia in patients with pretransplantation cytogenetic abnormalities, myelodysplastic syndrome, or acute leukemia. J Clin Oncol May 1;31(13):1669-76. 2013.

176. Dix D, Cellot S, Price V, Gillmeister B, Ethier MC, Johnston DL, lewis v, Michon B, Mitchell D, Stobart K, Yanofsky R, Portwine C, Silva M, Bowes L, Zelcer S, Brossard J, Traubici J, Allen U, Beyene J, Sung L. Association

between corticosteroids and infection, sepsis, and infectious death in pediatric acute myeloid leukemia (AML): results from the Canadian infections in AML research group. Clin Infect Dis Dec;55(12):1608-14. 2012.

177. Hale GA, Arora M, Ahn KW, He W, Camitta B, Bishop MR, Bitan M, Cairo MS, Chan K, Childs RW, Copelan E, Davies SM, Perez MA, Doyle JJ, Gale RP, Vicent MG, Horn BN, Hussein AA, Jodele S, Kamani NR, Kasow KA, Kletzel M, Lazarus HM, lewis va, Myers KC, Olsson R, Pulsipher M, Qayed M, Sanders JE, Shaw PJ, Soni S, Stiff PJ, Stadtmauer EA, Ueno NT, Wall DA, Grupp SA. Allogeneic hematopoietic cell transplantation for neuroblastoma: the CIBMTR experience. Bone Marrow Transplant. 2013;48(8):1056-64.

178. luca P, Hamilton J, Mahmud FH, Usher-Smith J. Ask the Experts: Paediatric Type 1 diabetes: adjunctive therapies, celiac disease and the role of the primary care physician. Diabetes Management. 2012; 2:489-495.

179. luca P, Chan M, Basak S, Segal A, Porepa M, Pinard M, Au, H and Birken C. A

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Qualitative Description of the Development and Evaluation of “Our Voice”, a Health Promotion Magazine Created by Paediatric Patients for Hospitalized Paediatric Patients. Hospital Paediatrics. 2013;3:59-64.

180. luca P*, Oren A*, Somers G and Urbach S. The Search For Ectopic ACTH Production In A 9 Year Old Boy. Journal of Paediatric Endocrinology and Metabolism, 2013;26(7-8):781-783. *Contributed equally

181. Jayanthan A, Cooper TM, Hoeksema KA, Lotfi S, Woldum E, lewis va, Narendran a. Occurrence and modulation of therapeutic targets of Aurora kinase inhibition in pediatric acute leukemia cells. Leuk Lymphoma Jul;54(7):1505-16. 2013.

182. Portwine C, Mitchell D, Johnston D, Gillmeister B, Ethier MC, Yanofsky R, Dix D, Cellot S, lewis v, Price V, Silva M, ZelcerS, Bowes L, Michon B, Stobart K, Brossard J, Beyene J, Sung L. Infectious events prior to chemotherapy initiation in children with acute myeloid leukemia. PLoS One Apr 26;8(4):e61899. 2013. Pound CM, Clark C, Ni A, Athale U, lewis v, Halton

JM. Corticosteroids, behavior, and quality of life in children treated for acute lymphoblastic leukemia; a multicentered trial. J Pediatr Hematol Oncol Oct;34(7):517-23. 2012.

183. Price V, Portwine C, Zelcer S, Ethier MC, Gillmeister B, Silva M, Schindera C, Yanofsky R, Mitchell D, Johnston DL, lewis v, Dix D, Cellot S, Michon B, Bowes L, Stobart K, Brossard J, Beyene J, Sung L. Clostridium difficile Infection in Pediatric Acute Myeloid Leukemia: From The Canadian Infections in Acute Myeloid Leukemia Research Group. Pediatr Infect Dis J Jun;32(6):610-613. 2013.

184. Siminoski K, Lee KC, Abish S, Alos N, Bell L, Blydt-Hansen T, Couch R, Cummings EA, Ellsworth J, Feber J, Fernandez CV, Halton J, Huber AM, Israels S, Jurencak R, Lang B, Laverdière C, LeBlanc C, lewis v, Midgley J, Miettunen PM, Oen K, Phan V, Pinsk M, Rauch F, Rodd C, Roth J, Saint-Cyr C, Scuccimarri R, Stephure D, Taback S, Wilson B, Ward LM; Canadian STOPP Consortium National Pediatric Bone Health Working Group. The development of bone mineral lateralization in

the arms. Osteoporos Int Mar;24(3):999-1006. 2013.

185. Siminoski K, Lee KC, Jen H, Warshawski R, Matzinger MA, Shenouda N, Charron M, Coblentz C, Dubois J, Kloiber R, Nadel H, O'Brien K, Reed M, Sparrow K, Webber C, Lentle B, Ward LM; STOPP Consortium (including lewis v). Anatomical distribution of vertebral fractures: comparison of pediatric and adult spines. Osteoporos Int Jul;23(7):1999-2008. 2012.

186. lowry rb, Bedard T, Sibbald B, Harder Jr, Trevenen C, Horobec V, Dyck JD. Congenital heart defects and major structural noncardiac anomalies in Alberta, Canada, 1995-2002. Birth Defects Res A Clin Mol Teratol. 2013 Feb;97(2): 79-86.

187. Bedard T, lowry rb, Sibbald B, Harder Jr, Trevenen C, Horobec V, Dyck JD. Congenital heart defect case ascertainment by the Alberta Congenital Anomalies Surveillance System. Birth Defects Res A Clin Mol Teratol. 2012 Jun;94(6):449-58.

188. R lowry rb, Bedard T, Sibbald B, Harder Jr,

189. Trevenen C, Horobec V, and Dyck JD.Congenital Heart Defects and Major Structural Noncardiac Anomalies in Alberta, Canada, 1995–2002. Plastic & Reconstructive Surgery: April 2013 – Volume 131 – Issue 4 – p649e-650e

190. luca NJ and Yeung RS. Epidemiology and Management of Kawasaki Disease. Drugs. 2012;72(8):1029-38.

191. luca NJ, Atkinson A, Hawkins C, Feldman BM. A Case of Anti-Signal Recognition Particle-Positive Juvenile Polymyositis Successfully Treated with Rituximab. J Rheumatol. 2012 Jul;39(7):1483-5.

192. luca NJ, Lara-Corrales I, Pope E. Eczema herpeticum in children: clinical features and factors predictive of hospitalization. J Pediatr. 2012 Oct;161(4):671-5.

193. luca NJ, Feldman BM. Pediatric Rheumatic Disease: Defining clinically inactive disease in juvenile dermatomyositis. Nat Rev Rheumatol. 2012 Oct 2.

194. Stinson JN, luca NJC, Jibb LA. Assessment and Management of Pain in Juvenile Idiopathic Arthritis. Pain Res Manage. 2012;17(6):391-396.

195. Carrey N, Bernier D, Emms M, Gunde E, Sparkes S, MacMaster FP, Rusak B. Smaller Volumes of Caudate Nuclei in Prepubertal Children with ADHD: Impact of Age. Journal of Psychiatric Research (2012) 46(8): 1066-1072

196. MacMaster FP, Carrey N, Langevin LM. Corpus Callosal Morphology in Early Onset Adolescent Depression. Journal of Affective Disorders (2013) 145 (2): 256-259.

197. Romo-Nava F, Hoogenboom WS, Pelavin PE, Alvarado JL, Bobrow LH, MacMaster FP, Keshavan M, McCarley RW, Shenton ME. Pituitary volume in schizophrenia spectrum disorders. Schizophrenia Research (2013) 146 (1-3): 301-307.

198. Kemp A, MacMaster FP, Jaworska N, Yang XR, Pradhan S, Mahnke D, Courtright A, Goodyear B, Ramasubbu R. Age of Onset and Corpus Callosal Morphology in Depression. Journal of Affective Disorders (2013) 150(2): 703-706.

199. Goia E, Hamilton L, Chan J, Wei XC, Mah JK, rho JM. Unilateral Foot Drop

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as an Initial Presentation of a Brain Tumor in a Child. J Child Neurol. 2013 Mar 1.[Epub ahead of print]

200. Katz SL, McKim D, Hoey L, Barrowman N, Kherani T, Kovesi T, MacLusky I, Mah JK. Respiratory management strategies for Duchenne muscular dystrophy: practice variation amongst Canadian sub-specialists. Pediatr Pulmonol. 2013 Jan;48(1):59-66.

201. Khan A, Trevenen Cl, Wei X-C, Sarnat Hb, Payne E, Kirton a. Alpers syndrome: The natural history of a case highlighting neuroimaging, neuropathology, and fat metabolism. J Child Neurol 2012;27:636-640.

202. O'Mahony J, Bar-Or A, Arnold DL, Sadovnick AD, Marrie RA, Banwell B; CanadianPediatric Demyelinating Disease Network.Collaborators: Wambera K, Connolly MB, Yager J, Mah JK, Booth F, Sebire G, CallenD, Meaney B, Dilenge ME, Lortie A, Pohl D, Doja A, Venketeswaran S, Levin S,MacDonald E, Meek D, Wood E, Lowry N, Buckley D, Yim C, Awuku M, Cooper P, Grand'Maison F, Baird J, Bhan V, Reginald A, McGowan M, Verhey L, Arnaoutelis R,Halliday

W, Marin S, Branson H. Masquerades of acquired demyelination in children: experiences of a national demyelinating disease program. J Child Neurol. 2013;28(2):184-97.

203. Sadaka Y, Verhey LH, Shroff MM, Branson HM, Arnold DL, Narayanan S, Sled JG, Bar-Or A, Sadovnick AD, McGowan M, Marrie RA, Banwell B; Canadian Pediatric Demyelinating Disease Network. [Mah, JK] 2010 McDonald criteria for diagnosing pediatric multiple sclerosis. Ann Neurol. 2012;72(2):211-23.

204. Ariane Larouche, Geneviève Gaëtan, Nabil El-Bilali, Mathieu Quesnel-Vallières, Steven r. Martin, Fernando Alvarez, Naglaa H. Seronegative Hepatitis C Infection in a Child Infected via Mother-to-Child Transmission.  Journal of Clinical Microbiology 2012; 50:2515-2519.

205. Myers KA, Mcleod dr, bello-espinosa l. Infantile ictal apneas in a child with Williams-Beuren syndrome. Pediatr Neurol. 2013;48(2):149-51.

206. Vallerand I, Mclennan Jd. Child and adolescent mental health service management strategies that may influence wait times. Journal of the

Canadian Academy of Child and Adolescent Psychiatry 2013;22(2):159-165.

207. Mclennan Jd, Doig J, Rasmussen C, Hutcheon E, Urichuk. Stress and relief: parents attending a respite program. Journal of the Canadian Academy of Child and Adolescent Psychiatry 2012;21(4):261-269.

208. Lazarevic D, Pistorio A, Palmisani E, Miettunen P, Ravelli A, Pilkington C, Wulffraat NM, Malattia C, Garay SM, Hofer M, Quartier P, Dolezalova P, Penades IC, Ferriani VP, Ganser G, Kasapcopur O, Melo-Gomes JA, Reed AM, Wierzbowska M, Rider LG, Martini A, Ruperto N; Paediatric Rheumatology International Trials Organisation (PRINTO). The PrINTO criteria for clinically inactive disease in juvenile dermatomyositis. Ann Rheum Dis. 2013 May;72(5):686-93.

209. Siminoski K, Lee KC, Abish S, Alos N, Bell L, Blydt-Hansen T, Couch R, Cummings EA, Ellsworth J, Feber J, Fernandez CV, Halton J, Huber AM, Israels S, Jurencak R, Lang B, Laverdière C, LeBlanc C, Lewis V, Midgley J, Miettunen PM, Oen K, Phan V, Pinsk M, Rauch F, Rodd C, Roth J, Saint-Cyr C, Scuccimarri R, Stephure

D, Taback S, Wilson B, Ward LM Canadian STOPP Consortium National Pediatric Bone Health Working Group. The Development of Bone Mineral Lateralization in the Arms. Osteoporos Int. 2013 Mar;24(3):999-1006.

210. Mineyko a, Kirton a. Mechanisms of pediatric cerebral arteriopathy: an inflammatory debate. Pediatr Neurol. 2013;48(1):14-23.

211. Mineyko a, Kirton a, Ng D, Wei XC. Normal intracranial periarterial enhancement on pediatric brain MR imaging. Neuroradiology. 2013;55(9):1161-9.

212. Mineyko a, Narendran a, Fritzler ML, Wei XC, Schmeling H, Kirton a. Inflammatory biomarkers of pediatric focal cerebral arteriopathy. Neurology 2012;79(13):1406-8.

213. Mineyko a, Wei X, Kirton a. Normal intracranial periarterial enhancement on pediatric brain MR imaging. Neuroradiol 2013, epub Jun 5.

214. Mineyko a, Kirton a. Mechanisms of arteriopathy in childhood stroke: An inflammatory debate. Ped Neurol 2013; 48(1):14-23.

215. Mineyko a, Narendran a, Fritzler ML, Wei X, Schmeling H, Kirton a. Inflammatory biomarkers of pediatric focal cerebral arteriopathy. Neurology 2012; 79:1406-8. epub Aug 22.

216. Leblanc CM, Lang B, Bencivenga A, Chetaille AL, Dancey P, Dent P, Miettunen P, Oen K, Rosenberg A, Roth J, Scuccimarri R, Tse SM, benseler S, Cabral DA, Campillo S, Chédeville G, Duffy CM, Duffy KW, Haddad E, Huber AM, Laxer R, Levy D, Johnson N, Ramsey S, Shiff N, Schmeling H, Schneider R, Stringer E, Yeung RS, Tucker LB. Access to biologic therapies in Canada for children with juvenile idiopathic arthritis. J Rheumatol. 2012 Sep;39(9):1875-9.

217. Leblanc CM, Lang B, Bencivenga A, Chetaille AL, Dancey P, Dent P, Miettunen P, Oen K, Rosenberg A, Roth J, Scuccimarri R, Tse SM, benseler S, Cabral DA, Campillo S, Chédeville G, Duffy CM, Duffy KW, Haddad E,Huber AM, Laxer R, Levy D, Johnson N, Ramsey S, Shiff N, Schmeling H, Schneider R, Stringer E, Yeung RS, Tucker LB: Access to biologic therapies in

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Canada for children with juvenile idiopathic arthritis. J Rheumatol 2012; 39(9): 1875-9.

218. Miettunen PM, lafay-Cousin l, guilcher gM, Nettel-aguirre a, Moorjani V. Widespread osteonecrosis in children with leukemia revealed by whole-body MRI.Clin Orthop Relat Res. 2012 Dec;470(12):3587-95.

219. Leblanc CM, Lang B, Bencivenga A, Chetaille AL, Dancey P, Dent P, Miettunen P, Oen K, Rosenberg A, Roth J, Scuccimarri R, Tse SM, benseler S, Cabral DA, Campillo S, Chédeville G, Duffy CM, Duffy KW, Haddad E, Huber AM, Laxer R, Levy D, Johnson N, Ramsey S, Shiff N, Schmeling H, Schneider R, Stringer E, Yeung RS, Tucker LB. Access to biologic therapies in Canada for children with juvenile idiopathic arthritis. J Rheumatol 2012 Sep;39(9):1875-9

220. Alos N, Grant RM, Ramsay T, Halton J, Cummings EA, Miettunen PM, Abish S, Atkinson S, Barr R, Cabral DA, Cairney E, Couch R, Dix DB, Fernandez CV, Hay J, Israels S, Laverdière C, Lentle B, lewis v, Matzinger M, Rodd C, Shenouda N, Stein R,

Stephure d, Taback S, Wilson B, Williams K, Rauch F, Siminoski K, Ward LM. High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapy. J Clin Oncol. 2012 Aug 1;30(22):2760-7.

221. Shiff NJ, Brant R, Guzman J, Cabral DA, Huber AM, Miettunen P, Roth J, Scuccimarri R, Alos N, Atkinson SA, Collet JP, Couch R, Cummings EA, Dent PB, Ellsworth J, Hay J, Houghton K, Jurencak R, Lang B, Larche M, Leblanc C, Rodd C, Saint-Cyr C, Stein R, Stephure D, Taback S, Rauch F, Ward LM; Canadian Steroid-associated Osteoporosis in the Pediatric Population Consortium. Glucocorticoid-related changes in body mass index among children and adolescents with rheumatic diseases.Arthritis Care Res (Hoboken). 2013 Jan;65(1):113-21.

222. Ortiz-Alvarez O, Mikrogianakis a, (Acute Care Committee) et al. CPS Position Statement: Managing the paediatric patient with an acute asthma exacerbation; Paediatr Child Health 2012;17(5):251-5. (National Guideline)

223. Friedman JN, Mikrogianakis a, (Acute Care Committee) et al. CPS Practice Point: Risk of acute hyponatremia in hospitalized children and youth receiving maintenance intravenous fluids; Paediatr Child Health 2013;18(2):102-104. (National Practice Point)

224. Farrell C, Mikrogianakis a, Cheng a (Acute Care Committee) et al. CPS Position Statement: Management of the Pediatric Patient with Acute Head Trauma. Pediatric Child Health, 2013; 18(5):253-8. C (National Guideline)

225. Mineyko a, Narendran a, Fritzler ML, Wei XC, Schmeling H, Kirton a. Inflammatory biomarkers of pediatric focal cerebral arteriopathy. Neurology 2012; 79(13): 1406-8.

226. Paes B, Mitchell I, Li A, Harimoto T, Lanctôt KL.

227. Respiratory-related hospitalizations following prophylaxis in the Canadian registry for palivizumab (2005-2012) compared to other international registries.

228. Clin Dev Immunol. 2013;2013:917068. doi: 10.1155/2013/917068. Epub 2013 Jun 19.

229. Szabo SM, Levy AR, Gooch KL, Bradt P, Wijaya H, Mitchell I. Elevated risk of asthma after hospitalization for respiratory syncytial virus infection in infancy.

230. Paediatr Respir Rev. 2013 Jan;13 Suppl 2:S9-15.

231. Szabo SM, Gooch KL, Bibby MM, Vo PG, Mitchell I, Bradt P, Levy AR. The risk of mortality among young children hospitalized for severe respiratory syncytial virus infection.

232. Paediatr Respir Rev. 2013 Jan;13 Suppl 2:S1-8.

233. Paes B, Mitchell I, Li A, Lanctôt KL; CARESS Investigators. A comparative study of respiratory syncytial virus (RSV) prophylaxis in premature infants within the Canadian Registry of Palivizumab (CARESS).

234. Eur J Clin Microbiol Infect Dis. 2012 Oct;31(10):2703-11. Epub 2012 May 1.

235. Manhas KP, Mitchell I. Extremes, uncertainty, and responsibility across boundaries: facets and challenges of the experience of transition to complex, pediatric home care.

236. J Child Health Care. 2012 Sep;16(3):224-36.

237. O'Keefe J, Byrne R, Montgomery M, Harder J, Roberts D, Sigalet DL. Longer term effects of closed repair of pectus excavatum on cardiopulmonary status. J Pediatr Surg. 2013 May;48(5):1049-54

238. Abd Elmoneim A, Gore L, Ricklis RM, Boklan J, Cooper T, Narendran a, Rolla K, Scott T, Arceci RJ. Phase I dose- escalation trial of clofarabine followed by escalating doses of fractionated cyclophosphamide in children with relapsed or refractory acute leukemias. Pediatr Blood Cancer Dec 15;59(7):1252-8. 2012.

239. August KJ, Narendran a, Neville KA. Pediatric relapsed or refractory leukemia: new pharmacotherapeutic developments and future directions. Drugs Apr;73(5):439-61. 2013.

240. de Oliveira JC, Brassesco MS, Scrideli CA, Tone LG, Narendran a. MicroRNA expression and activity in pediatric acute lymphoblastic leukemia (ALL). Pediatr Blood Cancer Oct;59(4):599-604. 2012.

241. Gore L, Trippett TM, Katzenstein HM, Boklan j, Narendran A, Smith

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A, Macy ME, Rolla K; for the Pediatric Oncology Experimental Therapeutics Investigators' Consortium (POETIC), Narashimhan N, Squillace RM, Turner CD, Haluska FG, Nieder M. A Multicenter, First-in-Pediatrics, Phase 1, Pharmacokinetic and Pharmacodynamic Study of Ridaforolimus in Patients with Refractory Solid Tumors. Clin Cancer Res Jul 1;19(13):3649-3658. 2013.

242. Lun X, Ruan Y, Jayanthan A, Liu DJ, Singh A, Trippett T, Bell J, Forsyth P, Johnston RN, Narendran a. Double-deleted vaccinia virus in virotherapy for refractory and metastatic pediatric solid tumors. Mol Oncol. 2013;7(5):944-54.

243. Macy ME, Duncan T, Whitlock J, Hunger SP, Boklan J, Narendren a, Herzog C, Arceci RJ, Bagatell R, Trippett T, Christians U, Rolla K, Ivy SP, Gore L; Pediatric Oncology Experimental Therapeutics Investigators' Consortium (POETIC). A multi-center phase Ib study of oxaliplatin (NSC#266046) in combination with fluorouracil and leucovorin in pediatric patients with advanced solid tumors. Pediatr Blood Cancer Feb;60(2):230-6. 2013.

244. Mineyko A, Narendran a, Fritzler ML, Wei XC, Schmeling H, Kirton a. Inflammatory biomarkers of pediatric focal cerebral arteriopathy. Neurology Sep 25;79(13):1406-8. 2012.

245. Sooriyaarachchi M, Narendran a, Gailer J. N-acetyl-L-cysteine modulates the metabolism of cis-platin in human plasma in vitro. Metallomics Mar;5(3):197-207. 2013.

246. Sooriyaarachchi M, Narendran a, Gailer J. The effect of sodium thiosulfate on the metabolism of cis-platin in human plasma in vitro. Metallomics Aug 24;4(9):960-7. 2012.

247. Romanow NTR, Couperthwaite A, McCormack GR, Nettel-aguirre a, Rowe BH, Hagel be. Assessing inter-rater agreement of environmental audit data in a matched case-control study on bicycling injuries. Injury Prevention. Inj Prev. 201;19(5):336-41. Epub 2013 Jan 30

248. Russell K, Meeuwisse WH; Nettel-aguirre a, emery Ca, Wishart J, Romanow N, Rowe BH, Goulet C, Hagel be. Characteristics of injuries sustained by snowboarders in a terrain park. Clinical Journal

of Sport Medicine May 2013;23(3):p 172–177

249. Romanow, NTR, Couperthwaite A, McCormack GR, Nettel-aguirre a, Rowe BH, Hagel, be. Environmental determinants of bicycling injuries. Journal of Environmental and Public Health, 2012, Epub 2012 Nov 28.

250. Alexander R. Foster B, Tonelli M, Soo A, Nettel-aguirre a, Hemmelgarn B, Samuel S. Survival and Transplantation Outcomes of Children Less than Two Years of Age with End-Stage Renal Disease. Pediatr Nephrol. 2012 Oct;27(10):1975-83

251. Pacaud d, Kelley H, Downey A, Chiasson M. Successful Delivery of Diabetes Self-Care Education and Follow-Up through eHealth Media Can J Diabetes 36 (5): 257-262, 2012.

252. Wherrett D, Huot C, Pacaud d, Canadian Diabetes Association 2013 Clinical Practice Guidelines Expert Committee. Canadian Diabetes Association 2008 clinical practice guidelines for the prevention and management of diabetes in Canada: Type 1 Diabetes in Children and Adolescents. Can J Diabetes, 37 (suppl 1):S153-S162, 2013.

253. Win AK, Walters RJ, Buchanan DD, Jenkins MA, Sweet K, Frankel WL, de la Chappelle A, McKeone DM, Walsh MD, Clendenning M, Pearson SA, Pavluk E, Nagler B, Hopper JL, Gattas MR, Goldblatt J, George J, Suthers GK, Phillips KD, Woodall S, Arnold J, Tucker K, Field M, Greening S, Gallinger S, Aronson M, Perrier r, Woods MO, Green JS, Walker N, Rosty C, Parry S, Young JP. 2012. Cancer risks for relatives of patients with serrated polyposis. Am J Gastroenterol. 107(5); 770-8

254. Gambling in children and adolescents. Gupta R, Pinzon Jl, Canadian Paediatric Society, Adolescent Health Committee: Paediatr Child Health 2012;17(5):263-4

255. Pringsheim T , Lam D , Day L , Genge A , Hogan DB , Shevell M , Fortin CM , Maxwell C , Fiebelkorn G , barlow K , Kapral MK , Casha S , Mobach T, Johnston M , Jette N , Korngut L, "Validation and interpretation of neurological registry data.", The Canadian journal of neurological sciences. 2013; 40(4 Suppl 2) PubMed ID: 23787269

256. Schmidt B, Whyte R.K., Asztalos E.V, Moddemann

D, Poets C, rabi y, Solimano A, Roberts R.S, MSc for the Canadian Oxygen Trial (COT) Group. Effects of Targeting Higher vs Lower Arterial Oxygen Saturations on Death or Disability in Extremely Preterm Infants: A Randomized Clinical Trial. JAMA 2013; 309(20): 2111-2120, PMID 23644995.

257. Glauser TA, Cnaan A, Shinnar S, Hirtz DG, Dlugos D, Masur D, Clark PO, Adamson PC; Childhood Absence Epilepsy Study Team. [rho JM] Ethosuximide, valproic acid, andlamotrigine in childhood absence epilepsy: initial monotherapy outcomes at 12months. Epilepsia. 2013 Jan;54(1):141-55.

258. Kobow K, Auvin S, Jensen F, Löscher W, Mody I, Potschka H, Prince D, Sierra A, Simonato M, Pitkänen A, Nehlig A, rho JM. Finding a better drug for epilepsy: antiepileptogenesis targets. Epilepsia. 2012;53(11): 1868-76.

259. Patel M, rho JM. Sweets Are BAD for Seizures. Epilepsy Curr. 2012;12(6):218-9..

260. Ruskin DN, Svedova J, Cote JL, Sandau U, rho JM, Kawamura M Jr, Boison D, Masino SA. Ketogenic diet

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261. Simeone TA, Simeone KA, Samson KK, Kim do Y, rho JM. Loss of the Kv1.1 potassium channel promotes pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices. Neurobiol Dis. 2013; 54:68-81.

262. Masino SA, rho JM. Mechanisms of Ketogenic Diet Action. In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012.

263. rho JM, Zupec-Kania B, Masino SA: Ketogenic Diet and Epilepsy: The Role of Adenosine. In: Adenosine: A Key Link Between Metabolism and Central Nervous System Activity, Masino SA, Boison DEds.), Springer, 2013.

264. Appl Physiol Nutr Metab. 2012 Aug;37(4): 715-23..

265. An exploratory study of sodium, potassium, and fluid nutrition status of tube-fed nonambulatory

children with severe cerebral palsy.

266. McGowan JE, Fenton TR, Wade AW, Branton JL, robertson M.

267. Samuel S, Hemmelgarn B, Nettel-aguirre a, Foster B, Soo A, Alexander R, Tonelli M. Association Between Residence Locating and Likelihood of Transplantation Among Pediatric Dialysis Patients. Pediatr Transplant. 2012 Nov;16(7):735-41

268. Samuel S, Foster B, Hemmelgarn B, Nettel-auirre a, Crowshoe L, Alexader R, Soo A, Tonelli M. Incidence and Causes of End-Stage Renal Disease Among Aboriginal Children and Young Adults. CMAJ. 2012 Oct;184(14):E758-64

269. Alexander R, Hemmelgarn B, Wiebe N, Bello A, Morgan C, Samuel S, Klarenbach S, Curhan G, Tonelli M. Kidney Stones and Kidney Function Loss: A Cohort Study. BMJ. 2012 Aug29;345-:E5287

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Page 141: Department of Paediatrics Annual Report 2013-v2 · • Developmental Paediatrics – Dr. Ben Gibbard • Emergency Medicine – Dr. Izabella Sztukowski • Endocrinology – Dr. Jonathan

ACKNOWLEDGEMENTS

The Department of Paediatrics gratefully acknowledges and thanks the following persons and groups for their contributions to this report

DR. VALERIE KIRK Project manager

WILMA OLIVIER-WALDEN and IMAGINE/XEROX team Creative direction, design and print production

NICK HEAZELL Annual Report coordination, additional graphics and photography

TRACEy BOyLE Collation of publications and research materials

Special thanks also to The Alberta Children’s Hospital Foundation, Department Administrative staff, Section Chiefs, Department members and Administrative Assistants for their contributions.

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