DAU Columns Bulk Packing Material for Preparative ... · Bulk Packing Material for Preparative...
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Reliability • Reproducible column efficiency • Reliable hydraulic compression system, maintained by air pressure • Explosion-proof available • In accordance with European safety regulations Safety • Special hydraulics safety design: DAC hydraulics are separated from the column, thus there is no risk of contamination of the column bed with hydraulic liquid Co., Ltd. YMC Karasuma-Gojo Bld. 284 Daigo-cho, Karasuma Nisiiru Gojo-dori Shimogyo-ku, Kyoto 600-8106 Japan TEL. +81(0)75-342-4515, FAX +81(0)75-342-4550 www.ymc.co.jp America, Inc. 941 Marcon Boulevard Suite 201 Allentown, PA18109 USA TEL. +1-610-266-8650, FAX +1-610-266-8652 www.ymcamerica.com Europe GmbH Schöttmannshof 19 D-46539 Dinslaken Germany TEL. +49(0)2064/427-0, FAX +49(0)2064/427-222 www.ymc.de DAU Columns Preparative Dynamic Axial Compression Columns The Selectivity Company Ease of use • Fast and simple column packing procedure • Optional slurry packing unit for convenient column packing available • Easy unpacking: Unpacking under sealed condi- tions via outlet tube to prevent dispersal of gel • Design of piston, column seals and frits allows easy dismantling and service Flexibility • Compact design, mobile column stand • Column bed variable from 0 to 1000 mm • Suitable for virtually any packing material DAU-100-700S DAU-600-700 DAU columns 11/14_EN PRODUCT PHASE CODE PHASE (silica-based unless noted) PORE SIZE* (nm) PARTICLE SIZE* (µm spherical) CARBON LOAD** (%C) pH TYPICAL APPLICATIONS Reversed Phase C18 Triart Prep C18 TAS organic/inorganic hybrid particle, polymeric bonding 12; (20) 10; 15; 20 20 2.0-10.0 first choice for method development, most versatile phase ODS-A-HG AAG one of YMC’s international bestsellers, traditional high performance C18 silica 12; 20; 30 10; 15; 20; 50 17; 12; 7 2.0-7.5 pharmaceuticals, vitamins, peptides, PTC-amino acids, general purpose phase ODS-AQ-HG AQG “hydrophilic” endcapping, for 100% aqueous eluent systems, substantially increased retention of polar compounds 8; 12; 20 10; 15; 20; 50 15; 14; 10 2.0-7.5 strong polar compounds, pharmaceuticals, antibiotics, peptides and proteins, nucleic acids, amino acids and nucleotides C8 Triart Prep C8 TOS organic/inorganic hybrid particle, polymeric bonding (12); 20 10; 15; 20 14 2.0-10.0 proteins and peptides, general purpose phase C8-HG (Octyl) OCG traditional C8, high coverage monomeric bonding chemistry 12; 20; 30 10; 15; 20; 50 10; 7; 4 2.0-7.5 proteins and peptides, estrogens, general purpose phase YMCbasic BA specifically designed for the separation of basic compounds and peptides 20 10; 15; 20 7 2.0-7.5 basic molecules w/o modifiers, peptides Ph-HG (Phenyl) PHG monomeric bonded phenyl, the p electron interaction gives a separation selectivity different from ODS 12; (20; 30) 10; 15; 20; 50 9 2.0-7.5 phenols, fullerenes, sweeteners, aromatics C4 C4-HG (Butyl) BUG traditional C4, less hydrophobic surface structure than C8 packing material 12; 20; 30 10; 15; 20; 50 7; 5; 3 2.0-7.5 biological separations, polar compounds, proteins C1 TMS-HG (C1) TMG trimethylsilane bonding, excellent hydrolytic stability 12; (20; 30) 10; 15; 20; 50 4 2.0-7.5 water-soluble vitamins YMC Omega OMG specifically designed for the separation of polyunsaturated fatty acids proprietary 10; 20; 50 15 2.0-7.5 polyunsaturated fatty acids, EPA, DHA Normal Phase/HILIC NH 2 -HG (Amino) NHG primary amino derivative, high coverage monomeric bonding chemistry, suitable for HILIC 12; (20; 30) 10; 15; 20; 50 3 2.0-7.5 saccharides, nucleotides, water-soluble vitamins CN-HG (Cyano) CNG for RP and NP applications, useful also for SFC and HILIC 12; (20; 30) 10; 15; 20; 50 7 2.0-7.5 proteins, steroids, catechols, for SFC applications Diol-HG DLG for normal phase applications, high recovery for biological material, suitable for HILIC and SFC 12; 20; 30 10; 15; 20; 50 – 2.0-7.5 polar natural products, pharmaceuticals, for HILIC and SFC applications SIL-HG (Silica) SLG ultra high purity, high mechanical stability, suitable for HILIC and SFC 6; 8; 12; 20; 30 10; 15; 20; 50 – – small organic molecules, fat-soluble vitamins, tocopherols, steroids SIL (Silica) SL high purity, suitable for MPLC and column chromatography 6; 12 50; 75; 150 – – small organic molecules, fat-soluble vitamins, tocopherols, steroids SEC Diol-120 DLG versatile phase for gel filtration separations 12 10; 15; 20; 50 – 5.0-7.5 peptides, proteins, malto-oligosacchardes, MW 5,000 to 100,000 Diol-200 DLG versatile phase for gel filtration separations 20 10; 15; 20 – 5.0-7.5 peptides, proteins, malto-oligosacchardes, MW 10,000 to several 100,000 Diol-300 DLG versatile phase for gel filtration separations 30 10; 15; 20 – 5.0-7.5 peptides, proteins, malto-oligosacchardes, MW several 10,000 to 1,000,000 Chiral Chiral Amylose-C KAN polysaccharide chiral selector, coated type proprietary 10; 20 – – wide application range, SFC/SMB Chiral Cellulose-C KCN polysaccharide chiral selector, coated type proprietary 10; 20 – – wide application range, SFC/SMB Chiral Amylose-SA KSA polysaccharide chiral selector, immobilised type proprietary 10; 20 – 2.0-9.0 wide application range for RP, NP, SFC and SMB Chiral Cellulose-SB KSB polysaccharide chiral selector, immobilised type proprietary 10; 20 – 2.0-9.0 wide application range for RP, NP, SFC and SMB Chiral Prep CD ST ST cyclodextrin based stationary phase for chiral RP separations 12 10; 20; 50 – 2.0-7.0 chiral separations, structural isomers Chiral Prep CD PM PM phenyl modified cyclodextrin based phase, for NP and RP applications 12 10; 20; 50 – 2.0-7.0 chiral separations, structural isomers Chiral NEA (R) Chiral NEA (S) NR NS chiral polymer covalently bound to silica, 1-naphthylethylamine as chiral selector 30 10 – 2.0-6.5 chiral polar pharmaceutical compounds, chiral alcohols, amines and carboxylic acids, for SFC applications IEX BioPro Q QA high dynamic binding capacity, hydrophilic polymer anion exchange media porous 30; 75 – 2.0-12.0 monoclonal antibodies, proteins, IgG BioPro S SP high dynamic binding capacity, hydrophilic polymer cation exchange media porous 30; 75 – 2.0-12.0 monoclonal antibodies, proteins, IgG BioPro SmartSep Q QS high mechanical strength, hydrophilic polymer anion exchange media porous 10; 30 – 2.0-12.0 nucleic acid, antibody pharmaceuticals, and general peptides/proteins BioPro SmartSep S SS high mechanical strength, hydrophilic polymer cation exchange media porous 10; 30 – 2.0-12.0 insulin, antibody pharmaceuticals, and general peptides/proteins Bulk Packing Material for Preparative Chromatography Analytical grades (3 and 5 µm) are routinely available in pre-packed columns. Particle sizes as indicated. If not listed, please ask for quotation. Multi ton capacity. Email: [email protected] Customized packing materials available on request. Pore sizes in parenthesis on request. *Not all combinations available. **With respect to pore size. Website: www.ymc.de
Transcript of DAU Columns Bulk Packing Material for Preparative ... · Bulk Packing Material for Preparative...
Reliability• Reproduciblecolumnefficiency
• Reliablehydrauliccompressionsystem,maintainedbyairpressure
• Explosion-proofavailable
• InaccordancewithEuropeansafetyregulations
Safety
• Specialhydraulicssafetydesign:DAChydraulicsareseparatedfromthecolumn,thusthereisnoriskofcontaminationofthecolumnbedwithhydraulicliquid
Co., Ltd.YMCKarasuma-GojoBld.284Daigo-cho,KarasumaNisiiruGojo-doriShimogyo-ku,Kyoto600-8106JapanTEL.+81(0)75-342-4515,FAX+81(0)75-342-4550www.ymc.co.jp
America, Inc.941MarconBoulevardSuite201Allentown,PA18109USATEL.+1-610-266-8650,FAX+1-610-266-8652www.ymcamerica.com
Europe GmbHSchöttmannshof19D-46539DinslakenGermanyTEL.+49(0)2064/427-0,FAX+49(0)2064/427-222www.ymc.de
DAU ColumnsPreparative Dynamic Axial Compression Columns The Selectivity Company
Ease of use• Fastandsimplecolumnpackingprocedure
• Optionalslurrypackingunitforconvenientcolumnpackingavailable
• Easyunpacking:Unpackingundersealedcondi-tionsviaoutlettubetopreventdispersalofgel
• Designofpiston,columnsealsandfritsallowseasydismantlingandservice
Flexibility• Compactdesign,mobilecolumnstand
• Columnbedvariablefrom0to1000mm
• Suitableforvirtuallyanypackingmaterial
DAU-100-700S DAU-600-700
DAUcolumns11/14_EN
PROD
UCT
PHAS
ECO
DEPH
ASE
(sili
ca-b
ased
unl
ess
note
d)PO
RESI
ZE*
(nm
)
PART
ICLE
SIZE
*(µ
m s
pher
ical
)
CARB
ON L
OAD*
*(%
C)pH
TYPI
CAL
APPL
ICAT
IONS
Reversed Phase
C18
Tria
rt Pr
ep C
18TA
Sor
gani
c/in
orga
nic
hybr
id p
artic
le, p
olym
eric
bon
ding
12; (
20)
10; 1
5; 2
020
2.0-
10.0
first
cho
ice
for m
etho
d de
velo
pmen
t, m
ost v
ersa
tile
phas
e
ODS-
A-HG
AAG
one
of Y
MC’
s in
tern
atio
nal b
ests
elle
rs, t
radi
tiona
l hig
h pe
rform
ance
C18
sili
ca12
; 20;
30
10; 1
5; 2
0; 5
017
; 12;
72.
0-7.
5ph
arm
aceu
tical
s, v
itam
ins,
pep
tides
, PTC
-am
ino
acid
s,ge
nera
l pur
pose
pha
se
ODS-
AQ-H
GAQ
G“h
ydro
phili
c” e
ndca
ppin
g, fo
r 100
% a
queo
us e
luen
t sys
tem
s,su
bsta
ntia
lly in
crea
sed
rete
ntio
n of
pol
ar c
ompo
unds
8; 1
2; 2
010
; 15;
20;
50
15; 1
4; 1
02.
0-7.
5st
rong
pol
ar c
ompo
unds
, pha
rmac
eutic
als,
ant
ibio
tics,
pep
tides
and
prot
eins
, nuc
leic
aci
ds, a
min
o ac
ids
and
nucl
eotid
es
C8
Tria
rt Pr
ep C
8TO
Sor
gani
c/in
orga
nic
hybr
id p
artic
le, p
olym
eric
bon
ding
(12)
; 20
10; 1
5; 2
014
2.0-
10.0
prot
eins
and
pep
tides
, gen
eral
pur
pose
pha
se
C8-H
G (O
ctyl
)OC
Gtra
ditio
nal C
8, h
igh
cove
rage
mon
omer
ic b
ondi
ng c
hem
istry
12; 2
0; 3
010
; 15;
20;
50
10; 7
; 42.
0-7.
5pr
otei
ns a
nd p
eptid
es, e
stro
gens
, gen
eral
pur
pose
pha
se
YMCb
asic
BAsp
ecifi
cally
des
igne
d fo
r the
sep
arat
ion
of b
asic
com
poun
ds a
nd p
eptid
es20
10; 1
5; 2
07
2.0-
7.5
basi
c m
olec
ules
w/o
mod
ifier
s, p
eptid
es
Ph-H
G (P
heny
l)PH
Gm
onom
eric
bon
ded
phen
yl, t
he p
ele
ctro
n in
tera
ctio
ngi
ves
a se
para
tion
sele
ctiv
ity d
iffer
ent f
rom
ODS
12; (
20; 3
0)10
; 15;
20;
50
92.
0-7.
5ph
enol
s, fu
llere
nes,
sw
eete
ners
, aro
mat
ics
C4
C4-H
G (B
utyl
)BU
Gtra
ditio
nal C
4, le
ss h
ydro
phob
ic s
urfa
ce s
truct
ure
than
C8
pack
ing
mat
eria
l12
; 20;
30
10; 1
5; 2
0; 5
07;
5; 3
2.0-
7.5
biol
ogic
al s
epar
atio
ns, p
olar
com
poun
ds, p
rote
ins
C1
TMS-
HG (C
1)TM
Gtri
met
hyls
ilane
bon
ding
, exc
elle
nt h
ydro
lytic
sta
bilit
y12
; (20
; 30)
10; 1
5; 2
0; 5
04
2.0-
7.5
wat
er-s
olub
le v
itam
ins
YMC
Omeg
aOM
Gsp
ecifi
cally
des
igne
d fo
r the
sep
arat
ion
of p
olyu
nsat
urat
ed fa
tty a
cids
prop
rieta
ry10
; 20;
50
152.
0-7.
5po
lyun
satu
rate
d fa
tty a
cids
, EPA
, DHA
Normal Phase/HILIC
NH2-H
G (A
min
o)NH
Gpr
imar
y am
ino
deriv
ativ
e, h
igh
cove
rage
mon
omer
icbo
ndin
g ch
emis
try, s
uita
ble
for H
ILIC
12; (
20; 3
0)10
; 15;
20;
50
32.
0-7.
5sa
ccha
rides
, nuc
leot
ides
, wat
er-s
olub
le v
itam
ins
CN-H
G (C
yano
)CN
Gfo
r RP
and
NP a
pplic
atio
ns, u
sefu
l als
o fo
r SFC
and
HIL
IC12
; (20
; 30)
10; 1
5; 2
0; 5
07
2.0-
7.5
prot
eins
, ste
roid
s, c
atec
hols
, for
SFC
app
licat
ions
Diol
-HG
DLG
for n
orm
al p
hase
app
licat
ions
, hig
h re
cove
ry fo
r bio
logi
cal m
ater
ial,
suita
ble
for H
ILIC
and
SFC
12; 2
0; 3
010
; 15;
20;
50
–2.
0-7.
5po
lar n
atur
al p
rodu
cts,
pha
rmac
eutic
als,
for H
ILIC
and
SFC
app
licat
ions
SIL-
HG (S
ilica
)SL
Gul
tra h
igh
purit
y, hi
gh m
echa
nica
l sta
bilit
y, su
itabl
e fo
r HIL
IC a
nd S
FC6;
8; 1
2; 2
0; 3
010
; 15;
20;
50
––
smal
l org
anic
mol
ecul
es, f
at-s
olub
le v
itam
ins,
toco
pher
ols,
ste
roid
s
SIL
(Sili
ca)
SLhi
gh p
urity
, sui
tabl
e fo
r MPL
C an
d co
lum
n ch
rom
atog
raph
y6;
12
50; 7
5; 1
50–
–sm
all o
rgan
ic m
olec
ules
, fat
-sol
uble
vita
min
s, to
coph
erol
s, s
tero
ids
SEC
Diol
-120
DLG
vers
atile
pha
se fo
r gel
filtr
atio
n se
para
tions
1210
; 15;
20;
50
–5.
0-7.
5pe
ptid
es, p
rote
ins,
mal
to-o
ligos
acch
arde
s, M
W 5
,000
to 1
00,0
00
Diol
-200
DLG
vers
atile
pha
se fo
r gel
filtr
atio
n se
para
tions
2010
; 15;
20
–5.
0-7.
5pe
ptid
es, p
rote
ins,
mal
to-o
ligos
acch
arde
s,M
W 1
0,00
0 to
sev
eral
100
,000
Diol
-300
DLG
vers
atile
pha
se fo
r gel
filtr
atio
n se
para
tions
3010
; 15;
20
–5.
0-7.
5pe
ptid
es, p
rote
ins,
mal
to-o
ligos
acch
arde
s,M
W s
ever
al 1
0,00
0 to
1,0
00,0
00
Chiral
Chira
l Am
ylos
e-C
KAN
poly
sacc
harid
e ch
iral s
elec
tor,
coat
ed ty
pepr
oprie
tary
10; 2
0–
–w
ide
appl
icat
ion
rang
e, S
FC/S
MB
Chira
l Cel
lulo
se-C
KCN
poly
sacc
harid
e ch
iral s
elec
tor,
coat
ed ty
pepr
oprie
tary
10; 2
0–
–w
ide
appl
icat
ion
rang
e, S
FC/S
MB
Chira
l Am
ylos
e-SA
KSA
poly
sacc
harid
e ch
iral s
elec
tor,
imm
obili
sed
type
prop
rieta
ry10
; 20
–2.
0-9.
0w
ide
appl
icat
ion
rang
e fo
r RP,
NP, S
FC a
nd S
MB
Chira
l Cel
lulo
se-S
BKS
Bpo
lysa
ccha
ride
chira
l sel
ecto
r, im
mob
ilise
d ty
pepr
oprie
tary
10; 2
0–
2.0-
9.0
wid
e ap
plic
atio
n ra
nge
for R
P, NP
, SFC
and
SM
B
Chira
l Pre
p CD
ST
STcy
clod
extri
n ba
sed
stat
iona
ry p
hase
for c
hira
l RP
sepa
ratio
ns12
10; 2
0; 5
0–
2.0-
7.0
chira
l sep
arat
ions
, stru
ctur
al is
omer
s
Chira
l Pre
p CD
PM
PMph
enyl
mod
ified
cyc
lode
xtrin
bas
ed p
hase
, for
NP
and
RP a
pplic
atio
ns12
10; 2
0; 5
0–
2.0-
7.0
chira
l sep
arat
ions
, stru
ctur
al is
omer
s
Chira
l NEA
(R)
Chira
l NEA
(S)
NR NSch
iral p
olym
er c
oval
ently
bou
nd to
silic
a, 1
-nap
hthy
leth
ylam
ine
as c
hira
l sel
ecto
r30
10–
2.0-
6.5
chira
l pol
ar p
harm
aceu
tical
com
poun
ds, c
hira
l alc
ohol
s,am
ines
and
car
boxy
lic a
cids
, for
SFC
app
licat
ions
IEX
BioP
ro Q
QAhi
gh d
ynam
ic b
indi
ng c
apac
ity, h
ydro
phili
c po
lym
er a
nion
exc
hang
e m
edia
poro
us30
; 75
–2.
0-12
.0m
onoc
lona
l ant
ibod
ies,
pro
tein
s, Ig
G
BioP
ro S
SPhi
gh d
ynam
ic b
indi
ng c
apac
ity, h
ydro
phili
c po
lym
er c
atio
n ex
chan
ge m
edia
poro
us30
; 75
–2.
0-12
.0m
onoc
lona
l ant
ibod
ies,
pro
tein
s, Ig
G
BioP
ro S
mar
tSep
QQS
high
mec
hani
cal s
treng
th, h
ydro
phili
c po
lym
er a
nion
exc
hang
e m
edia
poro
us10
; 30
–2.
0-12
.0nu
clei
c ac
id, a
ntib
ody p
harm
aceu
tical
s, a
nd g
ener
al p
eptid
es/p
rote
ins
BioP
ro S
mar
tSep
SSS
high
mec
hani
cal s
treng
th, h
ydro
phili
c po
lym
er c
atio
n ex
chan
ge m
edia
poro
us10
; 30
–2.
0-12
.0in
sulin
, ant
ibod
y ph
arm
aceu
tical
s, a
nd g
ener
al p
eptid
es/p
rote
ins
Bulk
Packin
g M
ate
rial fo
r P
repara
tive
Chro
mato
gra
phy
Analyticalgrades(3and5µm)areroutinelyavailableinpre-packedcolumns.Particlesizesasindicated.Ifnotlisted,pleaseaskforquotation.Multitoncapacity.Email:[email protected]
Customizedpackingmaterialsavailableonrequest.Poresizesinparenthesisonrequest.*Notallcombinationsavailable.**Withrespecttoporesize.Website:www.ymc.de
Preparative DynamicAxialCompressionColumns
Product number DAU-50-700S DAU-100-700S DAU-150-700 DAU-200-700 DAU-300-700 DAU-450-700 DAU-600-700
Body
Inner diameter 50 mm 103 mm 151 mm 200 mm 300 mm 450 mm 600 mm
Length 700 mm
Packed bed length 100 – 400 mm
Inner finishing Electrolytic polishing after honing process
Roughness Ra 0.5
Maximum pressure 10 MPa, 100 bar 10 MPa, 100 bar 10 MPa, 100 bar 10 MPa, 100 bar 10 MPa, 100 bar 7 MPa, 70 bar 7 MPa, 70 bar
Temperature 10 – 40 °C
Dimensions700(W) x 600(D) x
1800(H) mm700(W) x 600(D) x
1900(H) mm600(W) x 600(D) x
1900(H) mm755(W) x 875(D) x
2060(H) mm940(W) x 1040(D) x
2240(H) mm1080(W) x 1280(D) x
2500(H) mm1800(W) x 1900(D) x
2900(H) mm
Installation heigth > 2.3 m > 2.5 m > 2.5 m > 3.0 m > 3.5 m > 4.0 m > 4.0 m
Weight 70 kg 130 kg 200 kg 350 kg 600 kg 3000 kg 3200 kg
Maximum Packing material 500 g 2 kg 5 kg 8 kg 17 kg 40 kg 70 kg
RecommendedPacking material
Silica-based packing material 10 µm and largerSilica-based packing
material 15 µm and largerSilica-based packing material 20 µm and larger
FilterMaterial SUS316L (Sintered filter)
Frit size 2 µm
Seal
Material PTFE
Type V-packing Uniquely developed sealing structure
FeatureV-packing seals
effectively in response to inner pressure of column
Packing seals effectively in response to inner pressure of column
Easy replacement
CylinderSource Airdriven hydraulic pump
Type Stainless steel rod, Oil cylinder
Operation
Switching valve Change orientation of Cylinder alignment (UP, DOWN, HOLD)
Pressure regulator Adjust pressure of Oil pump
Pressure meter Monitoring air operation and oil pressure
Wetted materialSUS316, SUS316L,
PTFE, PEEKSUS316, SUS316L, PTFE
Connection
Inlet/Outlet1/8” Swagelok
tube fitting1/4” Swagelok tube fitting
3/8” Swagelok tube fitting
1/2” Swagelok tube fitting
1” Swagelok tube fitting
Slurry port ISO 15A Sanitary ferrule ISO 1S Sanitary ferrule
Air Ø 6 One-touch fittings Ø 10 One-touch fittings
DA
U-5
0
DA
U-1
00
DA
U-1
50
DA
U-2
00
DA
U-3
00
DA
U-4
50
DA
U-6
00
