DAFTAR PUSTAKA - Diponegoro...
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68 DAFTAR PUSTAKA 1. Kementerian Kesehatan RI. Tuberkulosis: Temukan, Obati Sampai Sembuh. Jakarta: Kementerian Kesehatan RI; 2015. 2. World Health Organization. Global Tuberculosis Report 2015, 20th Edition. Geneva (Swiss): World Health Organization; 2015. 3. World Health Organization. Global Update on the Health Sector Response to HIV, 2014. Geneva (Swiss): World Health Organization; 2014. 4. Lorent N, Sebatunzi O, Mukeshimana G, Ende J Van den, Clerinx J. Incidence and Risk Factors of Serious Adverse Events during Antituberculous Treatment in Rwanda : A Prospective Cohort Study. PLoS ONE. 2011;6(5):1-9. 5. Padmapriyadarsini C, Narendran G, Swaminathan S. Diagnosis & Treatment of Tuberculosis in HIV Co-infected Patients. Indian J Med Res. 2011;134(6):850-65. 6. World Health Organization. Consolidated Guidelines on the Use of Antiretroviral Drugs For Treating and Preventing HIV Infection. Geneva (Swiss): World Health Organization; 2013. 7. Regazzi M, Carvalho AC, Villani P, Matteelli A. Treatment Optimization in Patients Co-Infected with HIV and Mycobacterium tuberculosis Infections: Focus on Drug–Drug Interactions with Rifamycins. Clin Pharmacokinet. 2014;53(6):489-507. 8. Arbex MA. Antituberculosis Drugs: drug interactions, adverse effects, and use in special situations. Part 1: first-line drugs. J bras pneumol.
Transcript of DAFTAR PUSTAKA - Diponegoro...
68
DAFTAR PUSTAKA
1. Kementerian Kesehatan RI. Tuberkulosis: Temukan, Obati Sampai
Sembuh. Jakarta: Kementerian Kesehatan RI; 2015.
2. World Health Organization. Global Tuberculosis Report 2015, 20th
Edition. Geneva (Swiss): World Health Organization; 2015.
3. World Health Organization. Global Update on the Health Sector Response
to HIV, 2014. Geneva (Swiss): World Health Organization; 2014.
4. Lorent N, Sebatunzi O, Mukeshimana G, Ende J Van den, Clerinx J.
Incidence and Risk Factors of Serious Adverse Events during
Antituberculous Treatment in Rwanda : A Prospective Cohort Study. PLoS
ONE. 2011;6(5):1-9.
5. Padmapriyadarsini C, Narendran G, Swaminathan S. Diagnosis &
Treatment of Tuberculosis in HIV Co-infected Patients. Indian J Med Res.
2011;134(6):850-65.
6. World Health Organization. Consolidated Guidelines on the Use of
Antiretroviral Drugs For Treating and Preventing HIV Infection. Geneva
(Swiss): World Health Organization; 2013.
7. Regazzi M, Carvalho AC, Villani P, Matteelli A. Treatment Optimization
in Patients Co-Infected with HIV and Mycobacterium tuberculosis
Infections: Focus on Drug–Drug Interactions with Rifamycins. Clin
Pharmacokinet. 2014;53(6):489-507.
8. Arbex MA. Antituberculosis Drugs: drug interactions, adverse effects, and
use in special situations. Part 1: first-line drugs. J bras pneumol.
69
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Lampiran 1. Ethical Clearance
77
Lampiran 2. Surat Izin Penelitian
78
Lampiran 3. Formulir permintaan data rekam medis
79
Lampiran 4. Output hasil statistik
Frequency Table
jenis_kelamin
Frequency Percent Valid Percent Cumulative Percent
Valid
Pria 66 73.3 73.3 73.3
Wanita 24 26.7 26.7 100.0
Total 90 100.0 100.0
usia
Frequency Percent Valid Percent Cumulative Percent
Valid
<60 88 97.8 97.8 97.8
>60 2 2.2 2.2 100.0
Total 90 100.0 100.0
IMT_underweight
Frequency Percent Valid Percent Cumulative Percent
Valid
Ya 41 45.6 51.3 51.3
Tidak 39 43.3 48.8 100.0
Total 80 88.9 100.0
Missing System 10 11.1
Total 90 100.0
IMT_normal
Frequency Percent Valid Percent Cumulative Percent
Valid Ya 34 37.8 42.5 42.5
80
Tidak 46 51.1 57.5 100.0
Total 80 88.9 100.0
Missing System 10 11.1
Total 90 100.0
IMT_preobese
Frequency Percent Valid Percent Cumulative Percent
Valid
Ya 5 5.6 6.3 6.3
Tidak 75 83.3 93.8 100.0
Total 80 88.9 100.0
Missing System 10 11.1
Total 90 100.0
imunodefisiensi
Frequency Percent Valid Percent Cumulative Percent
Valid
berat 85 94.4 94.4 94.4
tidak 5 5.6 5.6 100.0
Total 90 100.0 100.0
TBparu_BTApos
Frequency Percent Valid Percent Cumulative Percent
Valid
Ya 13 14.4 14.4 14.4
Tidak 77 85.6 85.6 100.0
Total 90 100.0 100.0
81
TBparu_BTAneg
Frequency Percent Valid Percent Cumulative Percent
Valid
Ya 63 70.0 70.0 70.0
Tidak 27 30.0 30.0 100.0
Total 90 100.0 100.0
TBextraparu
Frequency Percent Valid Percent Cumulative Percent
Valid
Ya 5 5.6 5.6 5.6
Tidak 85 94.4 94.4 100.0
Total 90 100.0 100.0
TBparu_extraparu
Frequency Percent Valid Percent Cumulative Percent
Valid
Ya 9 10.0 10.0 10.0
Tidak 81 90.0 90.0 100.0
Total 90 100.0 100.0
stadium_HIV
Frequency Percent Valid Percent Cumulative Percent
Valid
3 62 68.9 68.9 68.9
4 28 31.1 31.1 100.0
Total 90 100.0 100.0
82
koinfeksi
Frequency Percent Valid Percent Cumulative Percent
Valid
Ada 5 5.6 5.6 5.6
tidak ada 85 94.4 94.4 100.0
Total 90 100.0 100.0
OAT
Frequency Percent Valid Percent Cumulative Percent
Valid
dosis optimal 88 97.8 97.8 97.8
dosis tidak optimal 2 2.2 2.2 100.0
Total 90 100.0 100.0
ART
Frequency Percent Valid Percent Cumulative Percent
Valid lini 1 90 100.0 100.0 100.0
efek_samping
Frequency Percent Valid Percent Cumulative Percent
Valid
ada 21 23.3 23.3 23.3
tidak ada 69 76.7 76.7 100.0
Total 90 100.0 100.0
83
lama
Frequency Percent Valid Percent Cumulative Percent
Valid
<6 29 32.2 32.2 32.2
6-8 61 67.8 67.8 100.0
Total 90 100.0 100.0
Crosstabs
jenis_kelamin * efek_samping
Crosstab
efek_samping Total
ada tidak ada
jenis_kelamin
Pria
Count 16 50 66
Expected Count 15.4 50.6 66.0
% within jenis_kelamin 24.2% 75.8% 100.0%
% of Total 17.8% 55.6% 73.3%
Wanita
Count 5 19 24
Expected Count 5.6 18.4 24.0
% within jenis_kelamin 20.8% 79.2% 100.0%
% of Total 5.6% 21.1% 26.7%
Total
Count 21 69 90
Expected Count 21.0 69.0 90.0
% within jenis_kelamin 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
84
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square .114a 1 .735
Continuity Correctionb .003 1 .955
Likelihood Ratio .116 1 .733
Fisher's Exact Test 1.000 .487
Linear-by-Linear Association
.113 1 .737
N of Valid Cases 90
a. 0 cells (.0%) have expected count less than 5. The minimum expected count is 5.60.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
Odds Ratio for jenis_kelamin (Pria / Wanita) 1.216 .391 3.782
For cohort efek_samping = ada 1.164 .478 2.830
For cohort efek_samping = tidak ada .957 .748 1.224
N of Valid Cases 90
usia * efek_samping
Crosstab
efek_samping Total
ada tidak ada
usia <60
Count 21 67 88
Expected Count 20.5 67.5 88.0
85
% within usia 23.9% 76.1% 100.0%
% of Total 23.3% 74.4% 97.8%
>60
Count 0 2 2
Expected Count .5 1.5 2.0
% within usia 0.0% 100.0% 100.0%
% of Total 0.0% 2.2% 2.2%
Total
Count 21 69 90
Expected Count 21.0 69.0 90.0
% within usia 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square .623a 1 .430
Continuity Correctionb .000 1 1.000
Likelihood Ratio 1.077 1 .299
Fisher's Exact Test 1.000 .586
Linear-by-Linear Association
.616 1 .433
N of Valid Cases 90
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is .47.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
For cohort efek_samping = tidak ada .761 .677 .856
86
N of Valid Cases 90
IMT_underweight * efek_samping
Crosstab
efek_samping Total
ada tidak ada
IMT_underweight
Ya
Count 10 31 41
Expected Count 9.7 31.3 41.0
% within IMT_underweight
24.4% 75.6% 100.0%
% of Total 12.5% 38.8% 51.3%
Tidak
Count 9 30 39
Expected Count 9.3 29.7 39.0
% within IMT_underweight
23.1% 76.9% 100.0%
% of Total 11.3% 37.5% 48.8%
Total
Count 19 61 80
Expected Count 19.0 61.0 80.0
% within IMT_underweight
23.8% 76.3% 100.0%
% of Total 23.8% 76.3% 100.0%
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square .019a 1 .890
Continuity Correctionb .000 1 1.000
Likelihood Ratio .019 1 .890
Fisher's Exact Test 1.000 .550
87
Linear-by-Linear Association
.019 1 .891
N of Valid Cases 80
a. 0 cells (.0%) have expected count less than 5. The minimum expected count is 9.26.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
Odds Ratio for IMT_underweight (Ya / Tidak) 1.075 .383 3.015
For cohort efek_samping = ada 1.057 .481 2.321
For cohort efek_samping = tidak ada .983 .770 1.255
N of Valid Cases 80
IMT_normal * efek_samping
Crosstab
efek_samping Total
ada tidak ada
IMT_normal
Ya
Count 9 25 34
Expected Count 8.1 25.9 34.0
% within IMT_normal 26.5% 73.5% 100.0%
% of Total 11.3% 31.3% 42.5%
Tidak
Count 10 36 46
Expected Count 10.9 35.1 46.0
% within IMT_normal 21.7% 78.3% 100.0%
% of Total 12.5% 45.0% 57.5%
Total
Count 19 61 80
Expected Count 19.0 61.0 80.0
% within IMT_normal 23.8% 76.3% 100.0%
% of Total 23.8% 76.3% 100.0%
88
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square .242a 1 .623
Continuity Correctionb .051 1 .821
Likelihood Ratio .240 1 .624
Fisher's Exact Test .791 .408
Linear-by-Linear Association
.239 1 .625
N of Valid Cases 80
a. 0 cells (.0%) have expected count less than 5. The minimum expected count is 8.08.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
Odds Ratio for IMT_normal (Ya / Tidak) 1.296 .460 3.649
For cohort efek_samping = ada 1.218 .556 2.667
For cohort efek_samping = tidak ada .940 .730 1.210
N of Valid Cases 80
IMT_preobese * efek_samping
Crosstab
efek_samping Total
ada tidak ada
IMT_preobese Ya
Count 0 5 5
Expected Count 1.2 3.8 5.0
% within IMT_preobese 0.0% 100.0% 100.0%
89
% of Total 0.0% 6.3% 6.3%
Tidak
Count 19 56 75
Expected Count 17.8 57.2 75.0
% within IMT_preobese 25.3% 74.7% 100.0%
% of Total 23.8% 70.0% 93.8%
Total
Count 19 61 80
Expected Count 19.0 61.0 80.0
% within IMT_preobese 23.8% 76.3% 100.0%
% of Total 23.8% 76.3% 100.0%
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square 1.661a 1 .197
Continuity Correctionb .557 1 .456
Likelihood Ratio 2.814 1 .093
Fisher's Exact Test .332 .247
Linear-by-Linear Association
1.640 1 .200
N of Valid Cases 80
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 1.19.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
For cohort efek_samping = tidak ada 1.339 1.174 1.528
N of Valid Cases 80
90
imunodefisiensi * efek_samping
Crosstab
efek_samping Total
ada tidak ada
imunodefisiensi
berat
Count 20 65 85
Expected Count 19.8 65.2 85.0
% within imunodefisiensi 23.5% 76.5% 100.0%
% of Total 22.2% 72.2% 94.4%
tidak
Count 1 4 5
Expected Count 1.2 3.8 5.0
% within imunodefisiensi 20.0% 80.0% 100.0%
% of Total 1.1% 4.4% 5.6%
Total
Count 21 69 90
Expected Count 21.0 69.0 90.0
% within imunodefisiensi 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square .033a 1 .856
Continuity Correctionb .000 1 1.000
Likelihood Ratio .034 1 .854
Fisher's Exact Test 1.000 .669
Linear-by-Linear Association
.033 1 .857
N of Valid Cases 90
91
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 1.17.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
Odds Ratio for imunodefisiensi (berat / tidak) 1.231 .130 11.653
For cohort efek_samping = ada 1.176 .196 7.078
For cohort efek_samping = tidak ada .956 .607 1.505
N of Valid Cases 90
TBparu_BTApos * efek_samping
Crosstab
efek_samping Total
ada tidak ada
TBparu_BTApos
Ya
Count 2 11 13
Expected Count 3.0 10.0 13.0
% within TBparu_BTApos 15.4% 84.6% 100.0%
% of Total 2.2% 12.2% 14.4%
Tidak
Count 19 58 77
Expected Count 18.0 59.0 77.0
% within TBparu_BTApos 24.7% 75.3% 100.0%
% of Total 21.1% 64.4% 85.6%
Total
Count 21 69 90
Expected Count 21.0 69.0 90.0
% within TBparu_BTApos 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
92
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square .537a 1 .464
Continuity Correctionb .143 1 .705
Likelihood Ratio .581 1 .446
Fisher's Exact Test .725 .369
Linear-by-Linear Association
.531 1 .466
N of Valid Cases 90
a. 1 cells (25.0%) have expected count less than 5. The minimum expected count is 3.03.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
Odds Ratio for TBparu_BTApos (Ya / Tidak) .555 .113 2.730
For cohort efek_samping = ada .623 .164 2.365
For cohort efek_samping = tidak ada 1.123 .862 1.464
N of Valid Cases 90
TBparu_BTAneg * efek_samping
Crosstab
efek_samping Total
ada tidak ada
TBparu_BTAneg Ya
Count 18 45 63
Expected Count 14.7 48.3 63.0
% within TBparu_BTAneg 28.6% 71.4% 100.0%
% of Total 20.0% 50.0% 70.0%
93
Tidak
Count 3 24 27
Expected Count 6.3 20.7 27.0
% within TBparu_BTAneg 11.1% 88.9% 100.0%
% of Total 3.3% 26.7% 30.0%
Total
Count 21 69 90
Expected Count 21.0 69.0 90.0
% within TBparu_BTAneg 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
a. 0 cells (.0%) have expected count less than 5. The minimum expected count is 6.30.
b. Computed only for a 2x2 table
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square 3.221a 1 .073
Continuity Correctionb 2.319 1 .128
Likelihood Ratio 3.570 1 .059
Fisher's Exact Test .103 .060
Linear-by-Linear Association
3.185 1 .074
N of Valid Cases 90
a. 0 cells (.0%) have expected count less than 5. The minimum expected count is 6.30.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
Odds Ratio for TBparu_BTAneg (Ya / Tidak) 3.200 .856 11.965
For cohort efek_samping = ada 2.571 .826 8.009
For cohort efek_samping = tidak ada .804 .654 .987
94
N of Valid Cases 90
TBextraparu * efek_samping
Crosstab
efek_samping Total
ada tidak ada
TBextraparu
Ya
Count 0 5 5
Expected Count 1.2 3.8 5.0
% within TBextraparu 0.0% 100.0% 100.0%
% of Total 0.0% 5.6% 5.6%
Tidak
Count 21 64 85
Expected Count 19.8 65.2 85.0
% within TBextraparu 24.7% 75.3% 100.0%
% of Total 23.3% 71.1% 94.4%
Total
Count 21 69 90
Expected Count 21.0 69.0 90.0
% within TBextraparu 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square 1.611a 1 .204
Continuity Correctionb .526 1 .468
Likelihood Ratio 2.745 1 .098
Fisher's Exact Test .587 .256
95
Linear-by-Linear Association
1.593 1 .207
N of Valid Cases 90
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 1.17.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
For cohort efek_samping = tidak ada 1.328 1.176 1.500
N of Valid Cases 90
TBparu_extraparu * efek_samping
Crosstab
efek_samping Total
ada tidak ada
TBparu_extraparu
Ya
Count 1 8 9
Expected Count 2.1 6.9 9.0
% within TBparu_extraparu 11.1% 88.9% 100.0%
% of Total 1.1% 8.9% 10.0%
Tidak
Count 20 61 81
Expected Count 18.9 62.1 81.0
% within TBparu_extraparu 24.7% 75.3% 100.0%
% of Total 22.2% 67.8% 90.0%
Total
Count 21 69 90
Expected Count 21.0 69.0 90.0
% within TBparu_extraparu 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
96
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square .835a 1 .361
Continuity Correctionb .248 1 .618
Likelihood Ratio .965 1 .326
Fisher's Exact Test .679 .329
Linear-by-Linear Association
.826 1 .363
N of Valid Cases 90
a. 1 cells (25.0%) have expected count less than 5. The minimum expected count is 2.10.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
Odds Ratio for TBparu_extraparu (Ya / Tidak) .381 .045 3.238
For cohort efek_samping = ada .450 .068 2.969
For cohort efek_samping = tidak ada 1.180 .908 1.535
N of Valid Cases 90
stadium_HIV * efek_samping
Crosstab
efek_samping Total
ada tidak ada
stadium_HIV 3
Count 17 45 62
Expected Count 14.5 47.5 62.0
% within stadium_HIV 27.4% 72.6% 100.0%
% of Total 18.9% 50.0% 68.9%
97
4
Count 4 24 28
Expected Count 6.5 21.5 28.0
% within stadium_HIV 14.3% 85.7% 100.0%
% of Total 4.4% 26.7% 31.1%
Total
Count 21 69 90
Expected Count 21.0 69.0 90.0
% within stadium_HIV 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square 1.860a 1 .173
Continuity Correctionb 1.198 1 .274
Likelihood Ratio 1.987 1 .159
Fisher's Exact Test .281 .136
Linear-by-Linear Association
1.839 1 .175
N of Valid Cases 90
a. 0 cells (.0%) have expected count less than 5. The minimum expected count is 6.53.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
Odds Ratio for stadium_HIV (3 / 4) 2.267 .685 7.500
For cohort efek_samping = ada 1.919 .711 5.184
For cohort efek_samping = tidak ada .847 .683 1.050
N of Valid Cases 90
98
koinfeksi * efek_samping
Crosstab
efek_samping Total
ada tidak ada
koinfeksi
Ada
Count 0 5 5
Expected Count 1.2 3.8 5.0
% within koinfeksi 0.0% 100.0% 100.0%
% of Total 0.0% 5.6% 5.6%
tidak ada
Count 21 64 85
Expected Count 19.8 65.2 85.0
% within koinfeksi 24.7% 75.3% 100.0%
% of Total 23.3% 71.1% 94.4%
Total
Count 21 69 90
Expected Count 21.0 69.0 90.0
% within koinfeksi 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square 1.611a 1 .204
Continuity Correctionb .526 1 .468
Likelihood Ratio 2.745 1 .098
Fisher's Exact Test .587 .256
Linear-by-Linear Association
1.593 1 .207
N of Valid Cases 90
99
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 1.17.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
For cohort efek_samping = tidak ada 1.328 1.176 1.500
N of Valid Cases 90
OAT * efek_samping
Crosstab
efek_samping Total
ada tidak ada
OAT
dosis optimal
Count 21 67 88
Expected Count 20.5 67.5 88.0
% within OAT 23.9% 76.1% 100.0%
% of Total 23.3% 74.4% 97.8%
dosis tidak optimal
Count 0 2 2
Expected Count .5 1.5 2.0
% within OAT 0.0% 100.0% 100.0%
% of Total 0.0% 2.2% 2.2%
Total
Count 21 69 90
Expected Count 21.0 69.0 90.0
% within OAT 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
100
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square .623a 1 .430
Continuity Correctionb .000 1 1.000
Likelihood Ratio 1.077 1 .299
Fisher's Exact Test 1.000 .586
Linear-by-Linear Association
.616 1 .433
N of Valid Cases 90
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is .47.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
For cohort efek_samping = tidak ada .761 .677 .856
N of Valid Cases 90
ART * efek_samping
Crosstab
efek_samping Total
ada tidak ada
ART lini 1
Count 21 69 90
Expected Count 21.0 69.0 90.0
% within ART 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
Total Count 21 69 90
101
Expected Count 21.0 69.0 90.0
% within ART 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
Chi-Square Tests
Value
Pearson Chi-Square .a
N of Valid Cases 90
a. No statistics are computed because ART is a constant.
Risk Estimate
Value
Odds Ratio for ART (lini 1 / .) .a
a. No statistics are computed because ART is a constant.
lama * efek_samping
Crosstab
efek_samping Total
ada tidak ada
lama
<6
Count 21 8 29
Expected Count 6.8 22.2 29.0
% within lama 72.4% 27.6% 100.0%
% of Total 23.3% 8.9% 32.2%
6-8
Count 0 61 61
Expected Count 14.2 46.8 61.0
% within lama 0.0% 100.0% 100.0%
% of Total 0.0% 67.8% 67.8%
Total Count 21 69 90
102
Expected Count 21.0 69.0 90.0
% within lama 23.3% 76.7% 100.0%
% of Total 23.3% 76.7% 100.0%
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square 57.616a 1 .000
Continuity Correctionb 53.639 1 .000
Likelihood Ratio 63.627 1 .000
Fisher's Exact Test .000 .000
Linear-by-Linear Association
56.976 1 .000
N of Valid Cases 90
a. 0 cells (.0%) have expected count less than 5. The minimum expected count is 6.77.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
For cohort efek_samping = tidak ada .276 .153 .497
N of Valid Cases 90
fase_intensif * efek_samping
Crosstab
efek_samping Total
Ya Tidak
fase_intensif Ya
Count 17 8 25
Expected Count 18.1 6.9 25.0
103
% within fase_intensif 68.0% 32.0% 100.0%
% of Total 58.6% 27.6% 86.2%
Tidak
Count 4 0 4
Expected Count 2.9 1.1 4.0
% within fase_intensif 100.0% 0.0% 100.0%
% of Total 13.8% 0.0% 13.8%
Total
Count 21 8 29
Expected Count 21.0 8.0 29.0
% within fase_intensif 72.4% 27.6% 100.0%
% of Total 72.4% 27.6% 100.0%
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square 1.768a 1 .184
Continuity Correctionb .529 1 .467
Likelihood Ratio 2.819 1 .093
Fisher's Exact Test .552 .252
Linear-by-Linear Association
1.707 1 .191
N of Valid Cases 29
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 1.10.
b. Computed only for a 2x2 table
104
Risk Estimate
Value 95% Confidence Interval
Lower Upper
For cohort efek_samping = Ya .680 .520 .890
N of Valid Cases 29
fase_lanjutan * efek_samping
Crosstab
efek_samping Total
Ya Tidak
fase_lanjutan
Ya
Count 4 0 4
Expected Count 2.9 1.1 4.0
% within fase_lanjutan 100.0% 0.0% 100.0%
% of Total 13.8% 0.0% 13.8%
Tidak
Count 17 8 25
Expected Count 18.1 6.9 25.0
% within fase_lanjutan 68.0% 32.0% 100.0%
% of Total 58.6% 27.6% 86.2%
Total
Count 21 8 29
Expected Count 21.0 8.0 29.0
% within fase_lanjutan 72.4% 27.6% 100.0%
% of Total 72.4% 27.6% 100.0%
Chi-Square Tests
Value df Asymp. Sig. (2-sided)
Exact Sig. (2-sided)
Exact Sig. (1-sided)
Pearson Chi-Square 1.768a 1 .184
Continuity Correctionb .529 1 .467
105
Likelihood Ratio 2.819 1 .093
Fisher's Exact Test .552 .252
Linear-by-Linear Association
1.707 1 .191
N of Valid Cases 29
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 1.10.
b. Computed only for a 2x2 table
Risk Estimate
Value 95% Confidence Interval
Lower Upper
For cohort efek_samping = Ya 1.471 1.124 1.924
N of Valid Cases 29
106
Lampiran 5. Biodata mahasiswa
BIODATA MAHASISWA
Nama : Josephine Natalie
NIM : 22010112130153
Tempat, tanggal lahir : Jakarta, 26 Desember 1993
Alamat : Jl. Gading Elok Timur I BJ 2 no.9, Kelapa Gading, Jakarta
Utara 14240
Nomor telepon : (021) 4531286
Nomor HP : 085728751023
E-mail : [email protected]
Riwayat Pendidikan Formal
1. SD Don Bosco I Kelapa Gading Lulus tahun : 2006
2. SMP Don Bosco I Kelapa Gading Lulus tahun : 2009
3. SMA Don Bosco II Pulomas Lulus tahun : 2012
4. Fakultas Kedokteran Universitas Diponegoro Masuk tahun : 2012
