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D2 Sigurður Brynjólfsson
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Transcript of D2 Sigurður Brynjólfsson
GEOCHEM
Sigurður Brynjólfsson, ProfessorUniversity of Iceland/Center for Systems Biology
MissionTo develop CO2 from geothermal wells as a feedstock for biologically-based chemical synthesis
CO2 Chemistrybiology
electricity
Goal
• To develop an integrated scalable technology platform to produce a commodity and fine chemicals from geothermal fields worldwide
Photobioreactor (PBR)
Potential Advancements• New light emitting diode technology• Modularity and scalability
LED - Photobioreactor
Biology• Photosynthetic Organisms
– Chlamydomonas reinhardii– Chlorella vulgaris– Dunaliella Salinas– Blue-green algae
• Key factors in organism choice– Natural/adapted vs. genetically modified algae– Range of products achievable
• cosmetics, nutraceuticals, coloring agents, pharmaceuticals, commodity chemicals, fuels, etc.
Feedstocks
• Geothermal power plant gas profile collected– Mostly CO2 - H2, H2S in minor amounts
• Energy cost– Low– Produced on site
• Clean green technology
GeoChem...• Determining the key performance characteristics
of a core unit of a photo bioreactor-based factory• Designing and initiating scale-up of these units into
versatile modules• Determining the spectrum of algal strains that can
be cultivated with this system
• Engineering of Synechocystis– metabolic computational-driven design
of Synechocystis
05/01/2023
Products…
High value molecules
9
Growth rate
Effect of adaptive laboratory evolution (ALE) on growth rate and carotenoid accumulation in D. salina. Average growth rate indicated biomass produced per day during one cycle. All the cycles including cycle 0 were performed under a total light intensity of 170 µE/m2/s consisting of 42 µE/m2/s blue LED light and 128 µE/m2/s red LED light. Detailed data were presented in Table S1. The results are averaged from three independent experiments. Error bars indicate SD.
Oils, pigments,…
Systems biology
• Systems Biology is an emerging field which involves the study of an organism, viewed as an integrated and interacting network of genes, proteins and biochemical reactions, which give rise to life.
• This field is a natural response to the various genome projects which have revealed the entire genetic makeup of many different organisms.
• Knowing the entire components that make an organism present novel opportunities for engineering system analysis by integrating this with other types of data.
Power Plants ... Simulation
Network map => Mathematics
Acknowldement• Háskóli Íslands
– Weiqi Fu, – Elin Adda Steinarsdóttir– Ólafur S Andrésson– Zhiqian Yi
• Matís– Sindri Freyr Ólafsson– Sigurjón Arason
• Controlant– Ólafur Guðmundsson– Gísli Herjólfsson