CVN - Natascia Grimaldi

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Summary of CV

This section describes briefly a summary of your career in science, academic and research; themain scientific and technological achievements and goals in your line of research in the medium-and long- term. It also includes other important aspects or peculiarities.

2016-now PostDoctoral Fellow at ICMAB-CSIC, under the supervision of Dr N. Ventosa;2015-2016 Marie Curie Research Fellow at the start-up Nanomol Technologies SA (MarieCurie Grant Nano2Fun), supervisor Dr Sala; 2014-2015 Research Fellow at the Universityof Palermo; 2011-2014 PhD student in Chem. Eng. at the University of Palermo, supervisorProf. Dispenza and Prof. Al-Sheikhly (University of Maryland); 2005-2010 Bachelor andMaster Degrees in Chem. and Mater. Eng. from the same University, with the maximumaccreditation (110/110 with praise). My efforts as PhD student have been awarded by theRadiation Chemistry Gordon Research Conference Committee and by the Italian Associationof Chemistry for Engineering (best PhD thesis in 2014). Co-author of 16 papers, speaker/poster presenter at many International Conferences and participant in International ResearchProjects, many of them under the supervision of the International Atomic Energy Agency.My background as Chem. Eng. and Materials Scientist has drove me towards Innovativeand Challenging Technologies from one side and Advanced Engineered Materials on theother; common denominators of my Research Activity have been the establishment of un-conventional manufacturing strategies for the design & production of bio-hybrid, engineeredfunctional nanomaterials for Medicine. Under the supervision of Dr Dispenza, I was mainlydealing with the assessment of high-energy radiation processing as “elective” large-scalemanufacturing process for nanogels formation. My earlier Research Activities have beencarried out between the University of Palermo, Dept. of Chem. Eng. and the National ResearchCouncil, Institute of Biophysics. I had also joined Dr Al-Sheikhly group at the Universityof Maryland (USA), working among three different Institutes (University of Maryland, theNational Institute of Standards and Technology and the Brookhaven National Laboratory).I have been interested in Polymer and Radiation Chemistry. In the frame of the MarieCurie Project Nano2Fun, I have been focused on the design & development of a semi-continuous pilot-plant starting from a lab-scale plant, operating with supercritical fluids for theproduction of nanoparticles. Nowadays, I am focused on green and sustainable compressed-fluid technologies for chemical processes and large scale production of nanomaterials. I aminvolved in (i) design, synthesis and characterization of engineered nanoparticles for drugand gene delivery; (ii) CO2-based process for nanomaterials manufacturing at large-scale;(iii) study of a new class of CO2-based-surfactant-free, pressure responsive nanostructuremedia for high-added value particulate material production. I am strongly interacting both withpeople from the Academia or the Industry. I am also involved in teaching&tutorial activities,both in the class as lecturer and as tutor of master&PhD students. H2020 projects writer. Theinherent multidisciplinary nature of my projects give me the opportunity to interact everydaywith people with different scientific backgrounds and to broad my scientific knowledge. Livingabroad (USA, and now Spain) and join international groups have improved my communicationand interpersonal skills. Naturally occurring independent, curios and creative, the dynamic andstimulating environments which I have been exposed to have refined my capacity of beingmultitasking, independently carrying out my work, taking initiatives and managing my time.


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General quality indicators of scientific research

This section describes briefly the main quality indicators of scientific production (periods ofresearch activity, experience in supervising doctoral theses, total citations, articles in journals ofthe first quartile, H index...). It also includes other important aspects or peculiarities.

Scientific Papers: 16 ( 3 submitted)Patent: 1 under reviewConference Proceedings: 2Citations number according to Scopus: 82H-index: 6Total Q1 papers: 7

Research Activities:

2010-2015 (5 years) Dept. of Chem. Eng. Università di Palermo (Italy, supervisor Prof. C.Dispenza) & National Research Council (Italy, supervisor Dr D. Bulone) & Dept. of BiologyUniversità di Palermo (Italy, supervisor Prof. G. Ghersi)

2013 (6 months) University of Maryland (USA, supervisor Prof. M. Al-Sheikhly) & NationalInstitute of Standards and Technology (USA, supervisors Dr D. Poster and Dr W. Vreeland)

2013 (2 months) Brookhaven National Laboratory (USA, supervisor Dr J. Wishart)

2015-2016 (1 year) Nanomol Technologies SA (Spain, supervisor Dr S. Sala)

2015-2017 (2 years) ICMAB-CSIC(Spain, supervisor Dr N. Ventosa)

Short-visits to other facilities:

2011&2012 (multiple times, each for 1 week) Institute of Nuclear Chemistry andTechnology (Poland, session of e-beam irradiation)

2015 (multiple times) ICFO – The Institute of Photonic Sciences (Spain, Fluorescencecorrelation spectroscopy measurements)


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2015 (1 week) Institut Laue–Langevin (France, SANS measurements)

2015 (1 week) European Synchrotron Radiation Facility (France, SAXS measurements)

2016 (multiple times) IBEC-Institute for Bioengineering of Catalonia(Spain, STORMmeasurements)

2016 (1 week) National Research Council (Italy, DLS & MALS measurements)

2016 (multiple times) VHIR - Vall d'Hebron Institut de Recerca(Spain, biological assays)

Awards:

1 Student Grant Award at 10th meeting of the Ionizing Radiation and Polymers symposium.Kracow (Poland) 2012

2 Young Investigator speaker at the Gordon Research Conference on Radiation Chemistry.Andover (USA) 2014

3 Best PhD Disertation-Associazione Italiana di Chimica per Ingegneria. Lecce (Italy) 2014

4 Marie Curie Fellowship “Nano2fun”- Grant agreement ITN-2015-607721; FP7-Marie CurieActions.

International Projects:

1 2009-2012: International Atomic Energy Agency Coordinated Research Project onNanoscale Radiation Engineering for Biomedical Applications

2 2014-2018: International Atomic Energy Agency Coordinated Research Projecton Nanosized Delivery Systems for Radiopharmaceuticals

3 FP7-Marie Curie Grant Nano2Fun: Organic nanoparticles (ONPs) production usingcompressed fluid: scale-up of exiting lab-scale plant


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Natascia Grimaldi

Surname(s): GrimaldiName: NatasciaPassport: YA3386328ORCID: 0000-0001-7028-8052ResearcherID: F-9319-2016Date of birth: 07/11/1986Gender: FemaleNationality: ItalyCountry of birth: ItalyCity of birth: VeronaLand line phone: (+34) 600315538Email: [email protected]

Current professional situation

Employing entity: Instituto de Ciencia de losMateriales de Barcelona

Type of entity: State agency

Professional category: PostDoctoral FellowStart date: 02/04/2016Type of contract: Temporary Dedication regime: Full timePerformed tasks: PostDooctoral Fellow at ICMAB-CSIC with a strong background in ChemicalEngineering and Chemistry. I am currently involved in three Research line and my interests are focusedon the development of large-scale manufacturing process for nanodevices production, compressed-fluidtechnologies and nanomaterials for Advanced Medicine. I am also strongly involved in the writing ofResearch Projects and I am currently following 5 students (3 PhD students and 2 master students),working on different but complementary projects to mine. European Projects (H2020) writing-up.More in detail, 1. Design and synthesis of novel non-liposomal nanovesicles (QUATSOMES) for geneand drug delivery by the mean of compressed-fluid-based technologies. Design and synthesis ofnanomaterials with tailored-made properties (size, surface prop.s, morphology, functionality, chemicalstructure, colloidal stability, shelf-life) exploiting processes reliable at industrial level; Assembly ofbio-hybrid nanodevices using the previously mentioned nanocarriers as fundamental building blocks;Evaluation of the ability of such engineered-nanodevices to act as drug/gene delivery and bioimagingdevices. In-vitro and in-vivo evaluation assays. 2. Compressed-fluid-based technologies for theproduction of lipid-based nanoparticles at large-scale; DELOS-SUSP® technology for nanovesiclesproduction. Establishment of correlations between "material properties-DELOS-SUSP processparameters" by a deep physicochemical characterization of nanomaterials. Dynamic and Static LightScattering, SAXS, SANS, Nano Tracking Analisys, Zeta-potential, AFM liquid and air, Cryo-TEM,FT-IR and NMR are used for performing the product analysis. Achieving a high control over materialproperties and batch-to-batch reproducibility are two of the main goals of this part of my ResearchActivity. Scale-up of DELOS-SUSP technology: design of the new semi-continuous pilot-plant startingfrom the available lab-scale plant. Selection of the best operational parameters for switching fromthe batch mode to the continuous mode, evaluating also the economic aspect and safety impact ofthe process. 3. Surfactant-free, pressure-responsive μ-structured media generated with the aid ofsupercritical fluids as futurist universal green solvent for chemical processes Fundamental studies ona new class of "surfactant-free" μ-structured media. Understanding their properties in terms of size ofthe water-like and oil-like nanopockets, i.e. nanoreactors, through a combination of different techniques(High-pressure Raman Spectroscopy-SAXS-SANS); studying their pressure-switchability from on tooff mode; studying their viability as media for the controlled crystalization of active organic molecules,


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towards high quality added value particulate material; assessment of their scale-independency andtechnology scale-up. My Research Activity is strongly affected by my forma mentis as engineer; all thechallenges in fundamental research that I face to are finalized towards the development of innovativetechnologies in advanced sectors.

Previous positions and activities

Employing entity Professional category Start date1 Nanomol Technologies SA Marie Curie PostDoctoral Fellow 09/03/20152 Universitá di Palermo PostDoctoral Fellow 21/03/20143 Universitá di Palermo PhD student 01/01/20114 University of Maryland PhD student 12/04/20135 National Institute of Standards and

TechnologyPhD student 12/04/2013

6 Brookhavan National Laboratory PhD student 01/08/2013

1 Employing entity: Nanomol Technologies SA Type of entity: BusinessProfessional category: Marie Curie PostDoctoral FellowStart-End date: 09/03/2015 - 09/03/2016 Duration: 1 yearType of contract: Grant-assisted student (pre or post-doctoral, others)Dedication regime: Full timePerformed tasks: PostDoctoral Fellow at the spin-off company Nanomol Tech. involved in thenetwork of the Marie Curie ITN Nano2Fun. My main task was the Scale-up of a compressedFluid-based technology (DELOS-SUSP) already developed at lab-scale from the company. Ihave been also strongly involved in other projects dealing with the design and synthesis of newnanomaterials for drug-delivery and with the development of new scale-independent nanoreactors forchemical and industrial processes. Common denominator of all the projects has been the exploitationof compressed CO2 as elective, green solvent for large-scale production of nanomaterials. In orderto finalize my work, I have worked in team with peers and younger scientists of the company. Manytimes I have been the leader of the team, managing my time/tasks and the ones of the collaborators.I have written Research Projects and I have been involved in collaborations with external partners,either from the Industry or Academia.

2 Employing entity: Universitá di Palermo Type of entity: UniversityDepartment: Università di PalermoProfessional category: PostDoctoral FellowStart-End date: 21/03/2014 - 01/03/2015 Duration: 1 yearType of contract: Grant-assisted student (pre or post-doctoral, others)Dedication regime: Full timePerformed tasks: My interests were focused on Nanotechnology for Medicine and high-energyradiation processing for the production of engineered-nanostructures. More in detail, 1. Design andsynthesis of engineered-nanomaterials with tailored properties for Advanced Medicine, exploitingboth “conventional” and “alternative” synthetic routes. Inverse microemulsion polymerizationand crosslinking has been used as "convetional" strategies for PVP-based nanogels, whileradiation-induced crosslinking has been used as "alternative" strategies for the production of similarPVP-based nanogels. 2. Assembly of composite bio-hybrid nanodevices exploiting PVP-basednanogels as fundamental building block. Conjugation reactions involving PVP-based-nanogels assubstrates and bio-active molecules such drugs, peptides, antibodys, proteins, DNA etc as functionalmolecules. 3. Establishment of e-beam irradiation processing as reliable manufacturing process forthe generation of a wide family of polymer-based-nanocarriers that can constitute a “base materialplatform” for the treatment and diagnosis of various diseases. 4. Kinetic and mechanistic studies,


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carried out using research-type electron accelerators, in order to master the relationship betweene-beam irradiation processing and product properties and, in turn, optimize both product designand manufacturing process conditions. 5. Biological evaluation of PVP-based-nanogels and theiroff-springs.Applicability in teaching and/or research: Seminars for the following classes: 1. Chemistry - BDin Chemical Engineering (30 hrs Practical work_classroom-problems)_Assisting Prof. G. Spadaro 2.Chemistry - BD in Mechanical Engineering (30 hrs Practical work_classroom-problems)_AssistingProf. C. Dispenza 3. Chemistry - BD in Managment Engineering (30 hrs Practicalwork_classroom-problems)_Assisting Prof. S. Alessi 4. Bionanomaterials-MD in ChemicalEngineering (10 hrs Lectures)_Assisting Prof. C. Dispenza TUTORIAL ACTIVITY FORUNDERGRADUATES STUDENTS ( 2 Italian students + 2 Polish students)

3 Employing entity: Universitá di Palermo Type of entity: UniversityProfessional category: PhD studentStart-End date: 01/01/2011 - 31/12/2014 Duration: 3 yearsType of contract: Grant-assisted student (pre or post-doctoral, others)Dedication regime: Full timePerformed tasks: During my PhD, a new promising approach based on e-beam radiation-inducedradical crosslinking of a water soluble, biocompatible synthetic polymer has been developed. Inparticular, the possibility of generating Poly-N-(Vinyl-Pyrrolidone)(PVP)-based nanocarriers, i.e.nanogels with a base PVP structure, tailored physico-chemical properties (particles size distribution,surface charge density) and multifunctionality has been explored. A thorough product analysis onthe generated nanoparticles through different characterization techniques, such as dynamic andstatic light scattering, photo-correlation spectroscopy, FT-IR, Raman, solid state NMR and XPSspectroscopies, SEM and AFM, has been carried. PVP-based nanogels have been then usedas building blocks for the assembly of tumor-target “composite” nanodevices. “Model” ligandswith various biological functions and drugs have been conjugated to the nanogels. Moreover, thebiocompatibility and localization pattern of the nanocarriers in cell cultures have been evaluated.It has been demonstrated that all the Nanogels (NGs) produced are biocompatible and able to beinternalized by cells. Furthermore, the many functional groups grafted on the NGs are availablefor coupling reactions with bioactive molecules, such as targeting moieties, drugs and metal-ionschelating agents. This collective evidence validates the generated nanostructures for the intentthey have been designed for, i.e. as nanocarriers in the biomedical field. E-beam irradiation usingindustrial type accelerators has demonstrated to be a viable manufacturing process since it grantshigh yields in terms of recovered product and high throughputs. Moreover, through a proper selectionof the experimental parameters, this approach has allowed to obtain NGs with the desired properties,in terms of size, surface charge density, degree of crosslinking and functionality.Applicability in teaching and/or research: Seminars for the following classes: 2011-2014Chemistry - BD in Chemical Engineering (30 hrs Practical work_classroom-problems)_AssistingProf. G. Spadaro 2011-2014 Chemistry - BD in Mechanical Engineering (30 hrs Practicalwork_classroom-problems)_Assisting Prof. C. Dispenza 2011-2014 Chemistry - BD in ManagmentEngineering (30 hrs Practical work_classroom-problems)_Assisting Prof. S. Alessi TUTORIALACTIVITY FOR UNDERGRADUATES STUDENTS (4 people)

4 Employing entity: University of Maryland Type of entity: UniversityProfessional category: PhD studentStart-End date: 12/04/2013 - 10/10/2013 Duration: 6 monthsType of contract: Grant-assisted student (pre or post-doctoral, others)Dedication regime: Full timePerformed tasks: Perfoming e-beam irradiations using the 10 MeV electron beam (Varian) locatedat the UMD for nanogels synthesis. Operator of CO-60 gamma cell. Characterization of nanogelsthrough AFM, AFFF, DLS, XPS Pulse-radiolysis studies using the apparatus available at the UMDAttending training and PhD coursesApplicability in teaching and/or research: Tutoring undergraduated students and training activityfor running the accelerator and the gamma cell.


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5 Employing entity: National Institute of Standardsand Technology

Type of entity: Technological Centre

Professional category: PhD studentStart-End date: 12/04/2013 - 10/10/2013 Duration: 6 monthsPerformed tasks: Develop of a new method for the estimation of the average hydrodynamic sizeand average molecular weight of nanogels using asymmetric flow field flow fractionation (AFFF)chromatography.

6 Employing entity: Brookhavan NationalLaboratory


Professional category: PhD studentStart-End date: 01/08/2013 - 30/09/2013 Duration: 2 monthsPerformed tasks: Pulse radiolysis experiments using the electron beam accelerator at BNL (Van DerGraft and LEAF e-beam).


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Education

University education

1st and 2nd cycle studies and pre-Bologna degrees

1 University degree: Master DegreeName of qualification: Master Degree in Chemical and Materials Engineering (2 years course)City degree awarding entity: Palermo, Sicilia, ItalyDegree awarding entity: Università di Palermo Type of entity: UniversityDate of qualification: 28/10/2010Average mark: ExcellentStandardised degree: Yes

2 Name of qualification: Bachelor Degree in Chemical and Materials Engineering (3 years course)City degree awarding entity: Palermo, Sicilia, ItalyDegree awarding entity: Università di Palermo Type of entity: UniversityDate of qualification: 31/03/2009Average mark: ExcellentStandardised degree: Yes

Doctorates

Doctorate programme: PhD in Chemical and Material EngeneeringDegree awarding entity: Università di Palermo andUniversity of Maryland

Type of entity: University

City degree awarding entity: Palermo, Sicilia, ItalyDate of degree: 21/03/2014European doctorate: NoThesis title: Polymeric and bio-hybrid nanovectors for drug-delivery and imaging devices.Thesis director: Clelia DispenzaThesis co-director: Mohamad Al-SheikhlyObtained qualification: PhDSpecial doctorate award: Yes Date of award: 15/09/2014

Language skills

Language Listening skills Reading skills Spoken interaction Speaking skills Writing skillsSpanish C1 C1 C1 C1 B1English C2 C2 C1 C1 C2Italian C2 C2 C2 C2 C2


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Teaching experience

General teaching experience

1 Type of teaching: Unofficial teachingName of the course: ChemistryType of programme: Bachelor’s degree Type of teaching: Practical work (classroom-problems)Type of subject: ObligatoryUniversity degree: Bachelor Degree in Chemical EngineeringStart date: 03/2014 End date: 06/2014Type of hours/ ECTS credits: HoursHours/ECTS credits: 30Entity: Università di PalermoCity of entity: Palermo, ItalySubject language: Italian

2 Type of teaching: Unofficial teachingName of the course: ChemistryType of programme: Bachelor’s degree Type of teaching: Practical work (classroom-problems)Type of subject: ObligatoryUniversity degree: Bachelor Degree in Mechanical EngineeringStart date: 03/2014 End date: 06/2014Type of hours/ ECTS credits: HoursHours/ECTS credits: 30Entity: Università di PalermoCity of entity: Palermo, ItalySubject language: Italian

3 Type of teaching: Unofficial teachingName of the course: BionanomaterialsType of programme: Master’s degree Type of teaching: Practical work (classroom-problems)Type of subject: OptionalUniversity degree: Master Degree in Chemical EngineeringFrequency of the activity: 4End date: 2014Type of hours/ ECTS credits: HoursHours/ECTS credits: 8Entity: Università di Palermo Type of entity: UniversityCity of entity: Palermo, ItalySubject language: Italian

4 Type of teaching: Unofficial teachingName of the course: ChemistryType of programme: Bachelor’s degree Type of teaching: Practical work (classroom-problems)Type of subject: ObligatoryUniversity degree: Bachelor Degree in Managment EngineeringStart date: 03/2012 End date: 06/2012


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Type of hours/ ECTS credits: HoursHours/ECTS credits: 30Entity: Università di Palermo Type of entity: UniversityCity of entity: Palermo, ItalySubject language: Italian


6 Type of teaching: Unofficial teachingName of the course: ChemistryType of programme: Bachelor’s degree Type of teaching: Practical work (classroom-problems)Type of subject: ObligatoryUniversity degree: Bachelor Degree in Mechanical EngineeringStart date: 03/2012 End date: 06/2012Type of hours/ ECTS credits: HoursHours/ECTS credits: 30Entity: Università di PalermoCity of entity: Palermo, ItalySubject language: Italian



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Experience supervising doctoral thesis and/or final year projects

1 Project title: Multifunctional nanovesicles for the diagnosis and treatment of colorectal cancer metastasisType of project: Doctoral thesisCo-director of thesis: MP Vinardell; N VentosaEntity: Universitat de Barcelona Type of entity: UniversityStudent: Guillem VargasDate of reading: 2020

2 Project title: Nanovesicles for neuroblastoma therapy with micro-RNACo-director of thesis: N Ventosa; M SeguraEntity: Universitat Autònoma de Barcelona Type of entity: UniversityStudent: Ariadna BoloixDate of reading: 2020

3 Project title: COMPLEXACIÓ D’OLIGONUCLEÒTIDS AMB QUATSOMES EN TAMPÓ D’HEPESType of project: End of course projectCo-director of thesis: Monica Muñoz; Nora VentosaEntity: Universitat Autònoma de Barcelona Type of entity: UniversityStudent: Guillem VargasObtained qualification: Màster in Bioquímica, Biologia Molecular i BiomedicinaDate of reading: 2016

4 Project title: Synthesis and Characterization of lipid-based nanovesicles by DELOS-susp technologyType of project: End of course projectCo-director of thesis: N GrimaldiEntity: Universitat Autònoma de Barcelona Type of entity: UniversityStudent: George Alvarado LopezObtained qualification: Master in Advanced Nanoscience and NanotechnologyDate of reading: 2016

5 Project title: Coniugazione nanoparticelle: applicazione biomedica e di imaging in vitroType of project: End of course projectCo-director of thesis: C DispenzaEntity: Universitá di Palermo- Dept. of Chem. Eng.Student: A AddamoObtained qualification: 2nd cycle degree in Chem. Eng. (Master Degree)Date of reading: 2014

6 Project title: SINTESI E CARATTERIZZAZIONE DI NANOGELS COME VETTORI DI AGENTI DI CONTRASTONELLA DIAGNOSTICA PER IMMAGINIType of project: End of course projectCo-director of thesis: C DispenzaEntity: Universitá di Palermo- Dept. of Biology and GeneticStudent: M Lo CocoObtained qualification: 2nd cycle degree in Biotechnology (Master Degree)Date of reading: 2014


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7 Project title: NANOVETTORI MULTIFUNZIONALI PER IL TRASPORTO E IL RILASCIO CONTROLLATO DIFARMACIType of project: End of course projectCo-director of thesis: C DispenzaEntity: Universitá di Palermo- Dept. of Chem. Eng.Student: L DittaObtained qualification: 2nd cycle degree in Chem. Eng. (Master Degree)Date of reading: 2013

8 Project title: INCORPORAZIONE E VEICOLAZIONE DI ANTITUMORALI MEDIANTE NANOPARTICELLEPOLIMERICHEType of project: End of course projectCo-director of thesis: C DispenzaEntity: Universitá di Palermo- Dept. of Chem. Eng.Student: F Di PisaObtained qualification: 2nd cycle degree in Chem. Eng. (Master Degree)Date of reading: 2012

9 Project title: Sintesi e caratterizzazione di Nanogeli per il rilascio controllato di farmaciType of project: End of course projectCo-director of thesis: C DispenzaEntity: Universitá di Palermo- Dept. of Chem. Eng.Student: L PisciottaObtained qualification: 2nd cycle degree in Chem. Eng. (Master Degree)Date of reading: 2011

Scientific and technological experience

Scientific or technological activities

R&D projects funded through competitive calls of public or private entities

1 Name of the project: Delivery Systems for RadiopharmaceuticalsType of project: Research and development,including transfer

Geographical area: INTERNATIONAL

Degree of contribution: ResearcherEntity where project took place: Università diPalermo


Type of participation: Team memberName of the programme: International Atomic Energy Agency Coordinated Research ProjectStart-End date: 2014 - 2018

2 Name of the project: Nanochemistry of molecular materials for 2-photon Functional applications(NANO2fUN)Type of project: Research and development,including transfer

Geographical area: European Union

Degree of contribution: ResearcherType of entity: Business


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Entity where project took place: NanomolTechnologies SAType of participation: Team memberName of the programme: Marie Curie Initial Training Network (ITN)Code according to the funding entity: Nano2FunStart-End date: 2013 - 2017Dedication regime: Full time

3 Name of the project: PON 2007-2013: "Soluzioni avanzate basate su biomateriali a matrici compositecomplesse per la riparazione e la rigenerazione della cartilagine articolare mediante tecnichemininvasive" (PON 0101287).Type of project: Research and development,including transfer

Geographical area: European Union

Degree of contribution: ResearcherEntity where project took place: Universitá diPalermo


Name principal investigator (PI, Co-PI....): Giulio GhersiType of participation: Team memberName of the programme: PON-Fondi Statali EuropeiCode according to the funding entity: PON 0101287Start-End date: 2007 - 2013

4 Name of the project: PON 2007-2013: Asse I. Asse I. Obiettivo 4.1.1.4. Progetto di potenziamentostrutturale: "Mediterranean Center for Human Health Advanced Biotechnologies" (Med-CHHAB)Type of project: Research and development,including transfer

Geographical area: Regional



Name principal investigator (PI, Co-PI....): Giulio GhersiType of participation: Team memberName of the programme: PON-Fondi Strutturali EuropeiStart-End date: 2007 - 2013

5 Name of the project: PON02003552964193-Sviluppo di Micro e Nano-Tecnologie e Sistemi Avanzati per laSalute dell’uomo - HIPPOCRATESType of project: Research and development,including transfer

Geographical area: National

Degree of contribution: ResearcherEntity where project took place: Universia diPalermo


Name principal investigator (PI, Co-PI....): Sabrina ConiciType of participation: Team memberName of the programme: Programma Operativo Nazionale “Ricerca e Competitività” 2007-2013Start-End date: 2007 - 2013

6 Name of the project: Nanoscale Radiation Engineering for Biomedical ApplicationsType of project: Research and development,including transfer

Geographical area: International




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Type of participation: Team memberName of the programme: International Atomic Energy Agency Coordinated Research ProjectStart-End date: 2009 - 2012

7 Name of the project: PRIN 2010/2011: Nanotecnologie molecolari per il rilascio controllato di farmaciType of project: Research and development, including transferDegree of contribution: ResearcherEntity where project took place: Università diPalermo


Type of participation: Team memberName of the programme: PRIN-Progetti di Ricerca di Interesse NazionaleCode according to the funding entity: NanomedStart-End date: 2010 - 2011

8 Name of the project: TERARMET: Desarrollo de terapias para el tratamiento de enfermedades rarasmetabólicas congénitasType of project: Industrial research Geographical area: RegionalName principal investigator (PI, Co-PI....): Nora ventosa; Eusebio Gainza GainzaType of participation: Team memberStart date: 2016

Results

Industrial and intellectual property

Title registered industrial property: Non-liposomal, functional nanovesicles for drug deliveryType of industrial property: Patent of inventionInventors/authors/obtainers: Natascia Grimaldi; Nora Ventosa; Santi Sala; Jaume VecianaEntity holder of rights: Instituto de Ciencia de los Materiales de BarcelonaDate of register: 2017


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Scientific and technological activities

Scientific production

Publications, scientific and technical documents

1 S Stehle; M Gaim; N Grimaldi; A Triolo; N Ventosa; A Brauer. A fast and remote screening method for watercontaining micro-emulsions. Submitted. 2017.Type of production: Scientific paper Format: Journal

2 N Grimaldi; PE Rojas; S Sala; A Cordoba; J Veciana; J Faraudo; A Braeuer; N Ventosa. CO2-basedsurfactant-free nanostructured liquids. Submitted. 2017.Type of production: Scientific paper Format: Journal

3 Irene Gonzalez; Laurines Cervera; Natascia Grimaldi; Nora Ventosa; Francesc Godia. Characterization ofDNA/PEI complex kinetics and its effect on transient transfection of mammalian cells. Submitted. 2017.Type of production: Scientific paper Format: Journal

4 Giorgia Adamo; Natascia Grimaldi; Maria Antonietta Sabatino; Marta Walo; Clelia Dispenza; Giulio Ghersi. E-beamcrosslinked nanogels decorated with monoclonal antibodies in targeting strategies. Biol. Chem.398 - 2, pp. 277 -287. 2016.Type of production: Scientific paper Format: JournalCorresponding author: No

5 Giorgia Adamo; Natascia Grimaldi; Simona Campora; Donatella Bulone; Maria Luisa Bondi; Mohamad Al-Sheikhly;Maria Antonietta Sabatino; Clelia Dispenza; Giulio Ghersi. Multi-Functional Nanogels for Tumor Targeting andRedox-Sensitive Drug and siRNA Delivery. Molecules. 21 - 11, pp. 1594. 2016.Type of production: Scientific paper Format: JournalCorresponding author: No

6 C Dispenza; M A Sabatino; N Grimaldi; M Mangione; M Walo; E Murugan; M Jonsson. On the origin offunctionalization in one-pot radiation synthesis of nanogels from aqueous polymer solutions. RSC Advances. 6, pp.2582 - 2591. 2016.Type of production: Scientific paper Format: Journal

7 C. Dispenza; N. Grimaldi; M.A. Sabatino; I.L. Soroka; M. Jonsson. Radiation-Engineered functional nanoparticlesin aqueous systems. Journal of Nanoscience and Nanotechnology. 15 - 5, pp. 3445 - 3467. 2015. Available on-lineat: <http://www.scopus.com/inward/record.url?eid=2-s2.0-84920742455&partnerID=MN8TOARS>.Type of production: Scientific paper Format: Journal

8 N. Grimaldi; M.A. Sabatino; G. Przybytniak; I. Kaluska; M.L. Bondì; D. Bulone; S. Alessi; G.Spadaro; C. Dispenza. High-energy radiation processing, a smart approach to obtain PVP-graft-AAnanogels. Radiation Physics and Chemistry. 94 - 1, pp. 76 - 79. 2014. Available on-line at:<http://www.scopus.com/inward/record.url?eid=2-s2.0-84887820125&partnerID=MN8TOARS>.Type of production: Scientific paper Format: JournalCorresponding author: Yes


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9 C. Dispenza; G. Adamo; M.A. Sabatino; N. Grimaldi; D. Bulone; M.L. Bondì; S. Rigogliuso;G. Ghersi. Oligonucleotides-decorated-poly(N-vinyl pyrrolidone) nanogels for genedelivery. Journal of Applied Polymer Science. 131 - 2, 2014. Available on-line at:<http://www.scopus.com/inward/record.url?eid=2-s2.0-84886597799&partnerID=MN8TOARS>.Type of production: Scientific paper Format: Journal

10 C. Dispenza; S. Rigogliuso; N. Grimaldi; M.A. Sabatino; D. Bulone; M.L. Bondì; G. Ghersi.Structure and biological evaluation of amino-functionalized PVP nanogels for fast cellularinternalization. Reactive and Functional Polymers. 73 - 8, pp. 1103 - 1113. 2013. Available on-line at:<http://www.scopus.com/inward/record.url?eid=2-s2.0-84884601965&partnerID=MN8TOARS>.Type of production: Scientific paper Format: Journal

11 C Dispenza; MA Sabatino; N Grimaldi; D Bulone; ML Buondì; MP Casaletto; S Rigogliuso; G Adamo; G Ghersi.Minimalism in Radiation Synthesis of Biomedical Functional Nanogels. Biomacromolecules. 13 - 6, pp. 1805 -1817. ACS Pubblication, 2012.Type of production: Scientific paper Format: Journal

12 C. Dispenza; N. Grimaldi; M.-A. Sabatino; S. Todaro; D. Bulone; D. Giacomazza; G. Przybytniak; S.Alessi; G. Spadaro. Studies of network organization and dynamics of e-beam crosslinked PVPs: Frommacro to nano. Radiation Physics and Chemistry. 81 - 9, pp. 1349 - 1353. 2012. Available on-line at:<http://www.scopus.com/inward/record.url?eid=2-s2.0-84863306737&partnerID=MN8TOARS>.Type of production: Scientific paper Format: JournalCorresponding author: Yes

13 G. Adamo; N. Grimaldi; S. Campora; M.A. Sabatino; C. Dispenza; G. Ghersi. Glutathione-sensitive nanogelsfor drug release. Chemical Engineering Transactions. 38, pp. 457 - 462. 2014. Available on-line at:<http://www.scopus.com/inward/record.url?eid=2-s2.0-84901419640&partnerID=MN8TOARS>.Type of production: Scientific book or monograph Format: Book

14 C. Dispenza; M.A. Sabatino; N. Grimaldi; G. Spadaro; D. Bulone; M.L. Bondì; G. Adamo;S. Rigogliuso. Large-scale radiation manufacturing of hierarchically assembled nanogels.Chemical Engineering Transactions. 27, pp. 229 - 234. 2012. Available on-line at:<http://www.scopus.com/inward/record.url?eid=2-s2.0-84864409268&partnerID=MN8TOARS>.Type of production: Scientific book or monograph Format: Book

15 S. Rigogliuso; M.A. Sabatino; G. Adamo; N. Grimaldi; C. Dispenza; G. Ghersi. Polymeric nanogels: Nanocarriersfor drug delivery application. Chemical Engineering Transactions. 27, pp. 247 - 252. 2012. Available on-line at:<http://www.scopus.com/inward/record.url?eid=2-s2.0-84864418814&partnerID=MN8TOARS>.Type of production: Scientific book or monograph Format: Book

16 Natascia Grimaldi; Fernanda Andrade; Nathaly Segovia; Lidia Ferrer-Tasies; Santi Sala; Jaume Veciana; NoraVentosa. Lipid-based nanovesicles for nanomedicine. Chemical Society Reviews. 45, pp. 6520 - 6545. 2016.Type of production: Review Format: JournalCorresponding author: No

17 Large-scale manufacturing of radiation sculptured therapeutic nanogels. Proceedings NSTI-Nanotech 2013,www.nsti.org. 3, pp. 202 - 205. 2013. ISBN 978-1-4822-0586-2Type of production: international conference proceedingsCorresponding author: Yes


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18 Water-borne Polymeric Nanoparticles for Glutathione-Mediated Intracellular Delivery of Anticancer Drugs.Proceedings of NSTI-Nanotech 2013, www.nsti.org. 3, pp. 155 - 158. 2013. ISBN 978-1-4822-0586-2Type of production: international conferenceproceedings

Format: Scientific and technical document or report

Corresponding author: Yes

Works submitted to national or international conferences

1 Title of the work: CO2-based-surfactant-free microemulsions-like system as futurist universal greenmedium for chemical processesName of the conference: NanoSpain 2016Type of event: ConferenceType of participation: Participatory - oral communicationCity of event: Logo+roño, SpainDate of event: 2016

2 Title of the work: CO2-based-surfactant-free microemulsions-like system as futurist universal greenmedium for chemical processes.Name of the conference: EMSF 2016.Type of event: ConferenceType of participation: Participatory - oral communicationCity of event: Essen, GermanyDate of event: 2016

3 Title of the work: DELOS-SUSP process: exploiting compressed CO2 for the production of bio-activenanovesicles at industrial levelName of the conference: Nano2Fun MeetingType of event: MeetingType of participation: Participatory - oral communicationCity of event: Hannover, GermanyDate of event: 2016

4 Title of the work: DELOS-SUSP process: exploiting compressed CO2 for the production of bio-activenanovesicles at industrial levelName of the conference: Material Research Society Fall Meeting 2015 (Micro- and Nanoscale Processingof Materials for Biomedical Devices)Type of event: ConferenceType of participation: Participatory - oral communicationCorresponding author: YesCity of event: Boston, United States of AmericaDate of event: 2015Natascia Grimaldi; Elisa Elizondo; Lidia Ferrer-Tasies; Maria Aguado; Dolores Bueno; Antonio Ardizzone;Elisabet Gonzalez; Santiago Sala; Nora Ventosa; Jaume Veciana.

5 Title of the work: Organic nanoparticles (ONPs) production using compressed fluid: scale-up of exitinglab-scale plantName of the conference: Nano2Fun-Mid Term MeetingType of event: Project MeetingType of participation: Participatory - oral communicationCorresponding author: YesCity of event: Barcelona, Spain


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Date of event: 2015

6 Title of the work: E-beam crosslinked PVP-based nanogels as building blocks for the assembly oftumor-target nanodevicesName of the conference: Convegno Nazionale dell'Associazione di Chimica per Ingegneria. AICIng2014Type of event: ConferenceType of participation: Participatory - invited/keynotetalk

Reasons for participation: Upon invitation

Corresponding author: YesCity of event: Lecce, ItalyDate of event: 2014Natascia Grimaldi.

7 Title of the work: E-beam crosslinked PVP-based nanogels as building blocks for the assembly oftumor-target nanodevicesName of the conference: Gordon Research Conferences on Radiation ChemistryType of event: ConferenceType of participation: Participatory - invited/keynotetalk

Reasons for participation: Upon invitation

Corresponding author: YesCity of event: Andover, United States of AmericaDate of event: 2014Natascia Grimaldi; Maria Antonietta Sabatino; Donatella Bulone; Giorgia Adamo; Giulio Ghersi; CleliaDispenza.

8 Title of the work: FOLATE-DECORATED E-BEAM CROSSLINKED NANOGELS TO ENHANCE UPTAKEBY TUMOR CELLS.Name of the conference: Convegno Nazionale della Società Italiana BiomaterialiType of event: ConferenceCity of event: Palermo, ItalyDate of event: 2014Giorgia Adamo; Natascia Grimaldi; A M Milioto; Maria Antonietta Sabatino; Clelia Dispenza; Giulio Ghersi.

9 Title of the work: Water-borne e-beam crosslinked nanogels as nanomaterials platform for drug delivery.Name of the conference: Convegno Nazionale della Società Italiana BiomaterialiType of event: ConferenceType of participation: Participatory - oral communicationCorresponding author: YesCity of event: Palermo, ItalyDate of event: 2014Natascia Grimaldi; Maria Antonietta Sabatino; Donatella Bulone; Giorgia Adamo; Giulio Ghersi; GiuseppeSpadaro; Clelia Dispenza.

10 Title of the work: Radiation Engineered Polymer Nanocarriers For A New Generation Of NanoparticleBased Tumor Specific Radiopharmaceuticals.Name of the conference: First Russian-Nordic Symposium on RadiochemistryType of event: ConferenceCity of event: Moscow, RussiaDate of event: 2013Clelia Dispenza; Maria Antonietta Sabatino; Lorena Ditta; Natascia Grimaldi; Maria Mangione; GiorgiaAdamo; Silvia Rigogliuso; Donatella Bulone; Giulio Ghersi; Mats Jonsson.


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11 Title of the work: Radiation processing: a versatile methodology to tune the structure of polymeric materialsName of the conference: Nanoscience and Nanotechnology 2013Type of event: ConferenceCity of event: Frascati, ItalyDate of event: 2013Giuseppe Spadaro; Maria Antonietta Sabatino; Natascia Grimaldi; Sabina Alessi; Giuseppe Pitarresi; Cleiladispenza.

12 Title of the work: Large-scale manufacturing of radiation sculptured therapeutic nanogels.Name of the conference: V WORKSHOP NAZIONALE AICIng-Tecnologie Chimiche per il Benessere e laSalute dell‘UomoType of event: WorkshopCity of event: Favignana, ItalyDate of event: 2013Clelia Dispenza; Maria Antonietta Sabatino; Natascia Grimaldi; Lorena Ditta; Sabina Alessi; GiuseppeSpadaro.

13 Title of the work: Large-scale manufacturing of radiation sculptured therapeutic nanogelsName of the conference: NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013City of event: Washington, United States of AmericaDate of event: 2013Clelia Dispenza; Natascia Grimaldi; Maria Antonietta Sabatino; Giorgia Adamo;Silvia Rigogliuso; giulio Ghersi. "Technical Proceedings of the 2013 NSTINanotechnology Conference and Expo, NSTI-Nanotech 2013". Available on-line at:<http://www.scopus.com/inward/record.url?eid=2-s2.0-84881107863&partnerID=MN8TOARS>.

14 Title of the work: Water-borne polymeric nanoparticles for glutathione-mediated intracellular delivery ofanticancer drugsName of the conference: NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013Corresponding author: YesCity of event: Washington, United States of AmericaDate of event: 2013Natascia Grimaldi; Maria Antonietta Sabatino; Donatella Bulone; Giorgia Adamo; SilviaRigogliuso; Giulio Ghersi; Clelia Dispenza. "Technical Proceedings of the 2013 NSTINanotechnology Conference and Expo, NSTI-Nanotech 2013". Available on-line at:<http://www.scopus.com/inward/record.url?eid=2-s2.0-84881098430&partnerID=MN8TOARS>.

15 Title of the work: High-energy radiation process, a “facile” and “versatile” approach to obtain PVP-graft-AAnanogelsName of the conference: 10th meeting of the Ionizing Radiation and Polymers symposium (IRaP)Type of event: ConferenceType of participation: Participatory - oral communicationCorresponding author: YesCity of event: Kracow, PolandDate of event: 2012With external admission assessment committee: YesNatascia Grimaldi; Maria Antonietta Sabatino; Gracina Przybytniak; Ivanka Kaluska; Giuseppe Spadaro;Clelia Dispenza.

16 Title of the work: Large-scale Radiation Manufacturing of Hierarchically Assembled NanogelsName of the conference: International conference on industrial biotechnology (IBIC 2012)Type of event: Conference


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City of event: Palermo, ItalyDate of event: 2012Clelia Dispenza; Maria Antonietta Sabatino; Natascia Grimaldi; Giuseppe Spadaro; Donatella Bulone; MariaLuisa Bondì; Giorgia Adamo; Silvia Rigogliuso.

17 Title of the work: Polymeric nanogels: Nanocarriers for drug delivery applicationName of the conference: International conference on industrial biotechnology (IBIC 2012)Type of event: ConferenceCity of event: Palermo, ItalyDate of event: 2012With external admission assessment committee: YesSilvia Rigogliuso; Maria Antonietta Sabatino; Giorgia Adamo; Natascia Grimaldi; Clelia Dispenza; GiulioGhersi.

18 Title of the work: Receptor-mediated Release of Chemotherapeutic Drugs from Water-borne BiohybridNanoparticles.Name of the conference: Gordon Research Conferences on Radiation ChemistryType of event: ConferenceCorresponding author: YesCity of event: Andover, United States of AmericaDate of event: 2012Natascia Grimaldi; Clelia Dispenza; Maria Antonietta Sabatino; Donatella Bulone; Maria Luisa Bondì; MariaPia Casaletto; Giorgia Adamo; Silvia Rigoogliuso; Giulio Ghersi.

19 Title of the work: Radiation sculptured nanogels as platform for novel therapeutic systemsName of the conference: VIII Convegno Nazionale dell'Associazione di Chimica per Ingegneria.AICIng2012City of event: Catania, ItalyDate of event: 2012Clelia Dispenza; Maria Antonietta Sabatino; Natascia Grimaldi; Sabina Alessi; Giuseppe Spadaro; MariaLuisa Bondì; Maria Pia Casaletto; Giorgia Adamo; Silvia Rigogliuso; Giulio Ghersi. ISBN 978-88-7051-226-7

20 Title of the work: Studies of network organisation and dynamics of e-beam crosslinked PVPs: from macroto nanoName of the conference: 12th Thiany SymposiumType of event: ConferenceCorresponding author: YesCity of event: Zalakaros, HungaryDate of event: 26/08/2011End date: 01/09/2011With external admission assessment committee: YesClelia Dispenza; Natascia Grimaldi; Maria Antonietta Sabatino; Simona Todaro; Donatella Bulone; DanielaGiacomazza; Gracina Przybytniak; Sabina Alessi; Giuseppe Spadaro.

21 Title of the work: Radiation-engineered functionalized nanogels as platform for biomedical nanocarriersName of the conference: 51° Simposio AFI RiminiType of event: ConferenceCity of event: Rimini, ItalyDate of event: 2011Clelia Dispenza; Maria Antonietta Sabatino; Donatella Bulone; Natascia Grimaldi; Giuseppe Spadaro; MariaLuisa Bondì; Silvia Rigogliuso; Giulio Ghersi.


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22 Title of the work: Multifunctional and bio-hybrid hydrogels as bioartificial matrices and drug delivery devicesName of the conference: Materiali POLIMERICI per dispositivi medici IMPIANTABILIType of event: WorkshopCity of event: Alessandria, ItalyDate of event: 2011Clelia Dispenza; Maria Antonietta Sabatino; Donatella Bulone; Natascia Grimaldi; Giuseppe Spadaro; MariaLuisa Boondì; Silvia Rigogliuso; Giulio Ghersi.

Other dissemination activities

Title of the work: Radiation Engineered Nanogels as Platform for Medical Diagnostics and TherapeuticsNanodevicesName of the event: 3rd RCM of the CRP on “Nanoscale Radiation Engineering for BiomedicalApplications".Type of event: MeetingCity of event: Kracow, PolandDate of event: 2012Organising entity: International Atomic Energy Agency (IAEA)Clelia Dispenza; Maria Antonietta Sabatino; Natascia Grimaldi; Sabina Alessi; Giuseppe Spadaro; SilviaRigogliuso; Giorgia Adamo; Giulio Ghersi.

Other achievements

Stays in public or private R&D centres

1 Entity: Nanomol Technologies SA Type of entity: BusinessCity of entity: Barcelona, SpainStart-End date: 09/03/2015 - 09/03/2016 Duration: 1 yearFunding entity: Marie Curie Grant ITN-2015-607721Name of programme: Nano2Fun: Organic nanoparticles (ONPs) production using compressed fluid:scale-up of exiting lab-scale plantGoals of the stay: Post-doctoral

2 Entity: Univeristà di Palermo Type of entity: UniversityCity of entity: Palermo, ItalyStart-End date: 21/03/2014 - 03/03/2015 Duration: 1 yearName of programme: Radiation Processing for the production of polymeric nanocarriers for drug andimaging agents deliveryGoals of the stay: Post-doctoral

3 Entity: University of Palermo Type of entity: UniversityFaculty, institute or centre: Dipartimento di Ingegneria Chimica, Informatica, Gestionale e MeccanicaCity of entity: Palermo, ItalyStart-End date: 01/01/2011 - 21/03/2014 Duration: 3 yearsGoals of the stay: Doctorate

4 Entity: University of Maryland Type of entity: UniversityCity of entity: College Park, United States of AmericaStart-End date: 09/04/2013 - 10/10/2013 Duration: 6 months


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Goals of the stay: Doctorate

5 Entity: National Institute of Standards & Technology(NIST)


City of entity: Gaithersburg, United States of AmericaStart-End date: 09/04/2013 - 10/10/2013 Duration: 6 monthsGoals of the stay: Guest

6 Entity: Brookhaven National Laboratory Type of entity: Technological CentreCity of entity: Upton, United States of AmericaStart-End date: 01/08/2013 - 30/09/2013 Duration: 2 monthsGoals of the stay: Guest

7 Entity: Institute of Nuclear Chemistry and Technology Type of entity: Technological CentreCity of entity: Warsaw, PolandStart-End date: 22/10/2012 - 27/10/2012 Duration: 5 daysGoals of the stay: Guest

8 Entity: Institute of Nuclear Chemistry and Technology Type of entity: Technological CentreCity of entity: Warsaw, PolandStart-End date: 13/06/2011 - 18/06/2011 Duration: 5 daysGoals of the stay: Guest

9 Entity: Instituto de Ciencia de los Materiales deBarcelona

Type of entity: State agency

City of entity: Barcelona, SpainStart date: 2016Name of programme: TERARMET- Development of therapies for the treatment of congenic metabolicdiseasesGoals of the stay: Post-doctoral

Prizes, mentions and distinctions

1 Description: Marie Curie FellowshipAwarding entity: Nano2Fun Marie Curie Initial Training Network (ITN)- FP7Conferral date: 2015

2 Description: Best PhD Disertation AwardAwarding entity: Associazione Italiana di Chimica per IngegneriaCity awarding entity: Lecce, ItalyConferral date: 2014

3 Description: Young Investigator speaker at the Gordon Research Conference (GRC)Awarding entity: Radiation Chemistry: Radiation Driven Processes in Physics, Chemistry, Biology, andIndustryCity awarding entity: Andover, United States of AmericaConferral date: 2014


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4 Description: Student Grant Award WinnerAwarding entity: 10th meeting of the Ionizing Radiation and Polymers symposium (IRaP)City awarding entity: Kracow, PolandConferral date: 2012

Summary of other achievements

1 Description of the achievement: Asymmetric Flow Field Fractionation TrainingAccrediting entity: National Institute of Standard andTechnology (NIST)

Type of entity: R&D Centre

City accrediting entity: United States of AmericaConferral date: 2013

2 Description of the achievement: Atomic Force Microscope in air and liquid phase trainingAccrediting entity: University of Maryland Type of entity: UniversityCity accrediting entity: College Park, United States of AmericaConferral date: 2013

3 Description of the achievement: Brookhaven National Laboratory (BNL) Mandatory TrainingAccrediting entity: Brookhaven National Laboratory(BNL)


City accrediting entity: Upton, United States of AmericaConferral date: 2013

4 Description of the achievement: Radiation Safety TrainingAccrediting entity: University of Maryland Type of entity: UniversityCity accrediting entity: College Park, United States of AmericaConferral date: 2013

5 Description of the achievement: Gricu PhD SchoolAccrediting entity: Gruppo dell'ingegneria chimicadell'Università

Type of entity: Associations and Groups

City accrediting entity: Cagliari, ItalyConferral date: 2011

6 Description of the achievement: Static and Dynamic Light Scattering TrainingAccrediting entity: Istituto di Biofisica-CentroNazionale Ricerche


Conferral date: 2010

CVN - Natascia Grimaldi

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Transcript of CVN - Natascia Grimaldi