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Revised: 6/22/2011

CURRICULUM VITAE Personal Information: • Name Kimberly Anne Kasow, DO • Business Address 170 Manning Drive, CB #7236

Chapel Hill, NC 27599-7236 • Phone (919) 966-1178

Education: ● Fellow, Division of Stem Cell Transplantation, Department of Hematology-Oncology, St.

Jude Children's Research Hospital, Memphis, Tennessee, 2000-2001 ● Fellow, Department of Hematology-Oncology, St. Jude Children’s Research Hospital,

Memphis, Tennessee, 1999-2003 ● Pediatric Resident, Department of Pediatrics, Columbus Children's Hospital, Columbus,

Ohio, 1996-1999 ● D.O., West Virginia School of Osteopathic Medicine, Lewisburg, West Virginia, 1996 ● B.A., University of Florida, Gainesville, Florida, 1991, Major – Religion, Minor – Jewish

Studies Professional Experience: ● Director of Pediatric Bone Marrow Transplantation, University of North Carolina at Chapel

Hill, Chapel Hill, North Carolina, 2009 – present ● Associate Professor, Division of Pediatric Hematology/Oncology, Department of Pediatrics,

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, 2009 – present ● Member, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel

Hill, Chapel Hill, North Carolina, 2009- present ● Transplant Quality Assurance and Quality Improvement Officer, University of North

Carolina- Chapel Hill, Chapel Hill, North Carolina, 2009 – present ● Bone Marrow Collections Medical Director, University of North Carolina- Chapel Hill,

Chapel Hill, North Carolina, 2009 – present

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● Transplant Quality Officer, Division of Bone Marrow Transplant and Cellular Therapy, St. Jude Children’s Research Hospital, Memphis, Tennessee, 2008-2009

● Director of Autologous Transplant Program, St. Jude Children's Research Hospital,

Memphis, Tennessee, 2008-2009 ● Assistant Professor, Department of Pediatrics, University of Tennessee, Memphis,

Tennessee, 2003-2009 ● Assistant Member, Division of Bone Marrow Transplantation and Cellular Therapy, St. Jude

Children’s Research Hospital, Memphis, Tennessee, 2003-2009 Honors and Awards:

● 2008 Recipient, Outstanding Physician of the Year, St. Jude Children's Research Hospital

● 1999 Recipient, Resident Teaching Award, OSU College of Medicine, Department of

Pediatrics • 1999 Children’s Research Symposium: Clinical Research – First Place; Silencing of

vasoactive intestinal peptide receptor gene in small cell lung caner: cause or effect; mentor: M. Sue O’Dorisio, MD, PhD.

• 1998 Grant Morrow Resident/Fellow Research Award: Fine mapping of the human VIP

receptor and analysis of receptor expression in human lung cancer; mentor: M. Sue O’Dorisio, MD, PhD; poster presentation at the 12th International Symposium on Regulatory Peptides, Mackinac Island, MI, September 1998.

• 1996 Janet M. Glasgow Memorial Achievement Citation - Graduated 4th in a class of 63

graduates • 1994 West Virginia School of Osteopathic Medicine, Outstanding Student in Osteopathic Medical Curriculum

• 1993 Member, Psi Sigma Alpha National Osteopathic Scholastic Honor Society

• 1993-94 President, Sigma Sigma Phi

• 1993 Member, Sigma Sigma Phi National Honorary Osteopathic Fraternity

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Bibliography: Book Chapters

• Kimberly A. Kasow, DO, and Gregory A. Hale, MD. Pediatric Aspects of Hematopoietic Stem Cell Transplantation. In: Hematopoietic Stem Cell Transplantation A Handbook for Clinicians, AABB, Bethesda, MD. Editors: John R. Wingard, Dennis A. Gastineau, Helen L. Leather, Zbigniew M. Szczepiorkowski, Edward L. Snyder, 2009.

• KA Kasow, GA Hale. Overview of Hematopoietic Stem Cell Transplantation. In: Encyclopedia of Cancer and Society, SAGE Publications, Inc., Thousand Oaks, CA. Editors: J. Geoffrey Golson, Graham A. Colditz, 2007.

Refereed papers/articles

• 1α, 25-dihydroxyvitamin D3 (vitamin D3) catalyzes suppressive activity on human natural regulatory T cells, uniquely modulates cell cycle progression and augments FOXP3. Morales-Tirado V, Wichlan DG, Leimig TE, Street SE, Kasow KA, Riberdy JM. Clin Immunol 138 (2): 212-221, 2011.

• Shaw PJ, Kan F, Ahn KW, Spellman SR, Aljurf M, Ayas M, Burke M, Cairo MS, Chen AR, Davies SM, Frangoul H, Gajewski J, Gale RP, Godder K, Hale GA, Heemskerk MBA, Horan J, Kamani N, Kasow KA, Chan KW, Lee SJ, Leung WH, Lewis VA, Miklos D, Oudshoorn M, Petersdorf EW, Ringden O, Sanders J, Schultz KR, Seber A, Setterholm M, Wall DA, Yu L, Pulsipher MA. Outcomes of pediatric bone marrow transplantation for leukemia and myelodysplasia using matched sibling, mismatched related or matched unrelated donors. Blood 116 (19): 4007-4015, 2010.

• Chotsampancharoen T, Gan K, Kasow KA, Barfield RC, Hale GA, Leung W. Iron overload in survivors of childhood leukemia after allogeneic hematopoietic stem cell transplantation. Pediatr Transplant 13(3): 348-352, 2009.

• Chen X, Knowles J, Barfield RC, Kasow KA, Madden R, Woodard P, Srivastava DK, Horwitz EM, Handgretinger R, Hale GA. A novel approach for quantification of KIR expression in healthy donors and pediatric recipients of hematopoietic SCTs. Bone Marrow Transplant 43(7): 525-532, 2009.

• Kasow KA, Krueger J, Srivastava DK, Li C, Barfield R, Leung W, Horwitz EM, Madden R, Woodard P, Hussain I, McCarville MB, Handgretinger R, Hale GA. Clinical utility of computed tomography screening of chest, abdomen, and sinuses before hematopoietic stem cell transplantation: The St. Jude Experience. Biol Blood Marrow Transplant 15(4): 490-495, 2009.

• Call SK, Kasow KA, Barfield R, Madden R, Leung W, Horwitz E, Woodard P, Panetta JC, Baker S, Handgretinger R, Rodman J, Hale GA. Total and active rabbit

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antithymocyte globulin (rATG; Thymoglobulin) pharmacokinetics in pediatric patients undergoing unrelated donor bone marrow transplantation. Biol Blood Marrow Transplant 15(2): 274-278, 2009.

• Chintagumpala M, Hassall T, Palmer S, Ashley D, Wallace D, Kasow KA, Merchant TE,

Krasin MJ, Dauser R, Boop F, Krance R, Woo S, Cheuk R, Lau C, Gilbertson R, Gajjar A. A pilot study of risk adapted radiotherapy and chemotherapy in patients with supratentorial PNET. Neuro Oncol 11(1): 33-40, 2009.

• Morris EB, Kasow K, Reiss U, Ellison D, Broniscer A. Bone marrow transplantation for severe aplastic anemia secondary to temozolomide. J Neurooncol 91(2):237-239, 2009.

• Barfield RC, Kasow KA, Hale GA. Advances in pediatric hematopoietic stem cell

transplantation. Cancer Biol Ther 7(10): 1533-1539; 2008. • Fouladi M, Chintagumpala M, Ashley D, Kellie S, Gururangan S, Hassall T, Stewart CF,

Gronewold L, Wallace D, Broniscer A, Hale GA, Kasow K, Merchant TE, Morris B, Krasin M, Kun LE, Boyett JM, Gajjar A. Amifostine protects against cisplatin-induced ototoxicity in children with average-risk medulloblastoma. J Clin Oncol 26(22): 3749-3755; 2008.

• Kasow KA, Stocks RM, Kaste SC, Donepudi S, Tottenham D, Schoumacher RA,

Horwitz EM. Comprehensive airway evaluation and management in children with malignant infantile osteopetrosis prior to hematopoietic stem cell transplantation. J Pediatr Hematol Oncol 30(3): 225-229; 2008.

• Leung W, Ahn H, Rose SR, Phipps S, Smith T, Gan K, O’Connor M, Hale GA, Kasow

KA, Barfield RC, Madden RM, Pui CH. A prospective cohort study of late sequelae of pediatric allogeneic hematopoietic stem cell transplantation. Medicine 86(4): 215-224; 2007.

• Kasow KA, King E, Rochester R, Tong X, Srivastava DK, Horwitz EM, Leung W,

Woodard P, Handgretinger R, Hale GA. Diagnostic yield of bronchoalveolar lavage is low in allogeneic hematopoietic stem cell recipients receiving immunosuppressive therapy or with acute graft-versus-host disease: the St. Jude experience, 1990-2002. Biol Blood Marrow Transplant 13(7): 831-837; 2007.

• Kasow KA, Sims-Poston L, Eldridge P, Hale GA. CD34+ Hematopoietic progenitor cell

selection of bone marrow grafts for autologous transplantation in pediatric patients. Biol Blood Marrow Transplant 13(5): 608-614; 2007.

• Kaste SC, Kasow KA, Horwitz EM. Quantitative bone mineral density assessment in

malignant infantile osteopetrosis: QCT and DXA. Pediatr Blood Cancer 48 (2): 181-185; 2007.

• Kasow KA, Leung W, Horwitz EM, Woodard P, Handgretinger R, Hale GA. EBV

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lymphoproliferative disease of host origin after haploidentical stem cell transplantation. Pediatr Blood Cancer 49(6): 869-872; 2007.

• Chen X, Hale GA, Barfield R, Benaim E, Leung WH, Knowles J, Horwitz EM, Woodard

P, Kasow K, Yusuf U, Behm FG, Hayden RT, Shurtleff SA, Turner V, Srivastava DK, Handgretinger R. Rapid immune reconstitution after a reduced-intensity conditioning regimen and a CD3-depleted haploidentical stem cell graft for paediatric refractory haematological malignancies. Br J Haematol 135 (4): 524-532; 2006.

• Yusuf U, Hale GA, Carr J, Gu Z, Benaim E, Woodard P, Kasow KA, Horwitz EM,

Leung W, Srivastava DK, Handgretinger R, Hayden RT. Cidofovir for the treatment of adenoviral infection in pediatric hematopoietic stem cell transplant patients. Transplantation 81 (10): 1398-1404, 2006.

• Tolar J*, Yang S*, Kasow K*, Eapen M*, Orchard P. Proceedings and abstracts of the

First International Symposium on Osteopetrosis: biology and therapy. October 23-24, 2003. Bethesda, Maryland, USA. J Bone Miner Res. 19(8): 1356-1375; 2004. *All authors contributed equally to the work.

• Woodard P, Helton K, McDaniel H, Khan RB, Thompson S, Hale G, Benaim E, Kasow

K, Leung W, Horwitz E, Srivastava DK, Tong X, Yusuf U, Cunningham JM, Handgretinger R. Encephalopathy in pediatric patients after allogeneic hematopoietic stem cell transplantation is associated with a poor prognosis. Bone Marrow Transplant 33(11): 1151-1157; 2004.

• Woodard P, Cunningham JM, Benaim E, Chen X, Hale G, Horwitz E, Houston J, Kasow

K, Leung W, Wang W, Yusuf U, Handgretinger R. Effective donor lymphohematopoietic reconstitution after haploidentical CD34(+)-selected hematopoietic stem cell transplantation in children with refractory severe aplastic anemia. Bone Marrow Transplant 33(4):411-418, 2004.

• Kasow K, Chen X, Knowles J, Houston J, Holladay M, Wichlan D, Handgretinger R,

Riberdy JM. Human CD4+CD25+ regulatory T cells share equally complex and comparable repertoires with CD4+CD25- counterparts. J Immunol 172(10):6123-6128, 2004.

• Kasow KA, Bonfim C, Asch J, Margolis DA, Jenkins J, Tamburro RF, Handgretinger R,

Horwitz EM. Malignant infantile osteopetrosis and primary pulmonary hypertension: a new combination? Pediatr Blood Cancer 42:190-194, 2004.

• Khan RB, Krasin MJ, Kasow K, Leung W. Use of cyclooxygenase-2 inhibitor to treat

induced brain necrosis and edema. J Pediatr Hematol Oncol 26(4):253-255, 2004.

• Horwitz EM, Kasow KA, Hoffman TJ. Clinical gene marking of mesenchymal cells. Cytotherapy 5(3):194-196, 2003.

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• Kasow K, Handgretinger R, Krasin MJ, Pappo AS, Leung W. Allogeneic graft-versus-tumor response in childhood melanoma. J Pediatr Hematol Oncol 25(12):982-986, 2003.

• Karacay B, O’Dorisio MS, Kasow K, Hollenback C, Krahe R. Expression and fine

mapping of vasoactive intestinal peptide receptor 1. J Mol Neurosci 17(3):311-324, 2001.

Published abstracts

• Kimberly A. Kasow, Renee Madden, Paul Eldridge, Nancy L. Wright, Madeline

O’Connor, Wing Leung, Gregory A. Hale. Parental donor hematopoietic cell transplantation for patients with severe aplastic anemia: The St. Jude Children’s Research Hospital experience. Biology of Blood and Marrow Transplantation. 16 (supplement 2): S253; 2010.

• Kimberly A. Kasow, Sue C. Kaste, Richard Lovins, Nancy L. Wright, Wing Leung, Gregory A. Hale, Edwin M. Horwitz. Favorable outcomes in patients with malignancy infantile osteopetrosis following haploidentical transplantation using a reduced intensity preparative regimen. Biology of Blood and Marrow Transplantation. 15 (supplement 2): 25; 2009.

• Kimberly A. Kasow, Raymond C. Barfield, Nancy L. Wright, Chenghong Li, Deo

Kumar Srivastava, Edwin M. Horwitz, Wing Leung, Paul Woodard, Laura C. Bowman, Rupert Handgretinger, Gregory A. Hale. A phase I/II study of cyclophosphamide and topotecan in patients with high-risk malignancies undergoing autologous hematopoietic stem cell transplantation: the St. Jude long-term follow-up. Biology of Blood and Marrow Transplantation. 15 (supplement 2): 72-73; 2009.

• Call SK, Kasow K, Barfield R, Leung W, Madden R, Horwitz E, Woodard P, Yusuf U,

Panetta JC, Baker S, Handgretinger R, Rodman J, Hale GA. Rabbit ATG (Thymoglobulin R) pharmacokinetics in pediatric patients receiving a matched unrelated donor bone marrow transplantation. Biology of Blood and Marrow Transplantation. 14 (supplement 2): 166-167; 2008. Presented as an oral presentation and a poster by Dr. Call.

• Wichlan DG, Shurtleff SA, Riberdy JM, Kasow KA. Resolution of IPEX and

achievement of complete donor CD3+CD4+ T-cell engraftment following a reduced intensity conditioning regimen and infusion of a T- and B- lymphocyte depleted allogeneic bone marrow graft. Poster presentation. Biology of Blood and Marrow Transplantation. 14 (supplement 2): 85; 2008.

• Kasow KA, Madden R, Barfield R, Leung W, Hale, GA. Haploidentical stem cell

transplantation using T- and B- lymphocyte depleted grafts following reduced intensity conditioning for Wiskott-Aldrich syndrome. Poster presentation. Biology of Blood and Marrow Transplantation. 14 (supplement 2): 78-79; 2008.

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• Christy M. Embrey, Kimberly A. Kasow, Janice M. Riberdy, Mary Ellen Conley, E. Victoria Turner. Hematopoietic stem cell transplantation for immune dysregulation, polyendocrinopathy X-linked syndrome (IPEX). The American Society for Histocompatibility and Immunogenetics, Minneapolis, Minnesota, October 8-12, 2007. Human Immunology 68: S130 (Abstract 58-W).

• Kimberly A. Kasow, Rose Mary S. Stocks, Sue C. Kaste, Robert Schoumacher, Edwin

M. Horwitz. Comprehensive airway evaluation and management in children with malignant infantile osteopetrosis. Poster presentation. EBMT, Lyons, France, March 25-28, 2007. BMT 39:S182-S193 (Abstract P786).

• Kimberly Kasow, Jennifer Krueger, James Okuma, Deo Kumar Srivastava, Gregory A.

Hale. Clinical utility of screening chest, abdomen, and sinus computed tomography prior to hematopoietic stem cell transplantation: the St. Jude experience. Poster presentation. EBMT, Lyons, France, March 25-28, 2007. BMT 39:S78 (Abstract P469).

• Kimberly Kasow, Leigh Sims-Poston, Paul Eldridge, Gregory Hale, Isolex Use of

Baxter Isolex® device for CD34+ hematopoietic progenitor cell selection of bone marrow grafts for autologous transplantation. Poster presentation. EBMT, Lyons, France, March 25-28, 2007. BMT 39:S78 (Abstract P468).

● Kimberly A. Kasow, Erin King, Richard J. Rochester, Xin Tong, Deo Kumar Srivastava,

Edwin M. Horwitz, Wing Leung, Paul Woodard, Rupert Handgretinger, Gregory A Hale. Acute graft-versus-host disease and immunosuppressive therapy identify patients less likely to have a diagnostic yield with a bronchoavleolar lavage: the St. Jude Experience 1990-2002. Poster presentation. 2006 BMT Tandem Meetings (IBMT/ASBMT). Honolulu, Hawaii; February 19, 2006.

• Hale G, Horwitz E, Leung W, Woodard P, Eldridge P, Yusuf U, Benaim E, Kasow K,

Srivastava, Handgretinger R. CD133+ hematopoietic cells successfully reconstitute hematopoiesis following autologous peripheral blood stem cell transplantation. Blood (Abstract #444, oral presentation), 2004.

• KA Kasow, X Chen, J Knowles, D Wichlan, R Handgretinger, JM Riberdy. Human CD4+CD25+ Regulatory T Cells Share Comparable and Equally Complex Repertoires with CD4+CD25- Counterparts. Poster presentation. Keystone Symposium: Regulatory/Suppressor T Cells. Banff, Alberta, Canada; March 11, 2004.

• Kasow KA, Bonfim C, Asch J, Margolis D, Jenkins J, Tamburro RF, Horwitz E. The

unexpected discovery and toxicity of pulmonary hypertension after hematopoietic stem cell transplantation for malignant osteopetrosis: the possible existence of a genetic link or a physiologic consequence. Blood 102(11):426b, 2003.

• Kasow KA, Chen X, Wichlan D, Handgretinger R, Riberdy JM. Human CD4+CD25+

regulatory T cells share equally complex and comparable repertoires with CD4+CD25- counterparts. Blood 102(11):56b, 2003.

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• Kasow K, Handgretinger R, Houston J, Holliday MA, Riberdy, J. Human CD4+CD25+ regulatory T -cells: thymus vs. peripheral blood. Blood 100(11):57b, 2002.

• Kasow K, Morris LM, Holland HK, Connaghan DG. Successful non-myeloablative stem

cell transplant in adult Diamond-Blackfan syndrome. Blood 100(11):427b-428b, 2002.

• Kasow K, Woodard P, Benaim E, Hale G, Leung W, Bowman L, Horwitz E. Engraftment of a T-cell depleted matched unrelated donor stem cell graft using a non-myeloablative conditioning. Blood 96(11):361b, 2000.

In press/submitted/in preparation papers/articles

● Kasow KA, Morales-Tirado V, Wichlan D, Shuertleff S, Abraham A, Persons DA,

Riberdy JM. Therapeutic in vivo selection of thymic-derived natural T-regulatory cells following non-myeloablative hematopoietic stem cell transplant for IPEX syndrome. (Submitted, Biology of Blood and Marrow Transplant)

● Kasow KA, Kaste SC, Lovins R, Wright NL, O’Connor M, Burnette K, Eldridge P,

Leung W, Handgretinger R, Hale GA, Horwitz EM. Curing children with malignant infantile osteopetrosis after partially matched family member transplantation using reduced intensity conditioning and T-cell depletion. (In preparation)

● Call SK, Cross SJ, Kasow KA, Rose CH, Panetta JC, Rodman J, Hale GA.

Pharmacokinetics of intravenous Busulfan in pediatric, adolescent, and young adult stem cell transplant recipients. (In preparation)

● Kasow KA, Stewart CF Barfield RC, Wright NL, Li C, Srivastava DK, Leung W,

Horwitz EM, Bowman LC, Handgretinger R, Hale GA. A phase I/II study of cyclophosphamide and topotecan in patients with high-risk malignancies undergoing autologous hematopoietic cell transplantation: The St. Jude long-term follow-up. (In preparation)

Refereed unpublished oral presentations and/or abstracts

• Fitzgerald, TM, D'Auria, JP, Moore, C, and Kasow, KA (2011, March). Understanding

the experiences of the young matched sibling hematopoietic stem cell donor. Poster presented at the College of William & Mary's 10th Annual Graduate Research Symposium, Williamsburg, Virginia. March 25-26, 2011.

• Kimberly A. Kasow, Renee Madden, Paul Eldridge, Nancy L. Wright, Madeline O’Connor, Wing Leung, Gregory A. Hale. Parental donor hematopoietic cell transplantation for patients with severe aplastic anemia: The St. Jude Children’s Research Hospital experience. Poster presentation, 2010 BMT Tandem meeting, Orlando, Florida, February 25, 2010.

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• Invited speaker, Welcome to the Challenges of Hematopoietic Stem Cell Transplantation. Presbyterian Blume Pediatric Hematology/Oncology Clinic, Charlotte, North Carolina, May 14, 2009.

• Invited speaker, Haploidentical Stem Cell Transplantation for Non-Malignant Diseases, Pediatric Hematology/Oncology Journal Club, Wake Forest University, Winston-Salem, North Carolina, April 16, 2009.

• Vanessa Morales-Tirado, David G. Wichlan, Kimberly Kasow, Janice M. Riberdy. Vitamin D3 as a potential mechanism to control suppressive function of human natural regulatory T cells. Poster presentation at Keystone Meeting in March 2009.

• Presenter, Kimberly A. Kasow, Sue C. Kaste, Richard Lovins, Nancy L. Wright, Wing

Leung, Gregory A. Hale, Edwin M. Horwitz. Favorable outcomes in patients with malignancy infantile osteopetrosis following haploidentical transplantation using a reduced intensity preparative regimen. Pediatric Best Abstracts, oral presenter, 2009 BMT Tandem meeting, Tampa, Florida, February 12, 2009.

• Kimberly A. Kasow, Raymond C. Barfield, Nancy L. Wright, Chenghong Li, Deo

Kumar Srivastava, Edwin M. Horwitz, Wing Leung, Paul Woodard, Laura C. Bowman, Rupert Handgretinger, Gregory A. Hale. A phase I/II study of cyclophosphamide and topotecan in patients with high-risk malignancies undergoing autologous hematopoietic stem cell transplantation: the St. Jude long-term follow-up. Poster presentation, 2009 BMT Tandem meeting, Tampa, Florida, February 12, 2009.

• Invited speaker to the ALSAC Gift Planning Team, St. Jude Children’s Research

Hospital, Memphis, Tennessee, January 13, 2009. • Invited speaker, St. Jude Hospital speaker for the Team ESA visit, St. Jude Children’s

Research Hospital, Memphis, Tennessee, December 5, 2008. • Invited speaker, Trasplante Hematopoyetico con Celulas de Cordon Umbilical, Session:

Trasplante de Medula Osea y Terapia Celular at II Curso Internacional de Oncologia (SOLCA), Cuenca, Equador, November 18, 2008.

• Invited speaker, Trasplante Hematopoyetico Autologo y Alogenico en Pediatria, Session:

Trasplante de Medula Osea y Terapia Celular at II Curso Internacional de Oncologia (SOLCA), Cuenca, Equador, November 18, 2008.

• Invited speaker, Welcome to the Challenges of Hematopoietic Stem Cell Transplantation.

Introduction to BMT for Nurses. Levine Children’s Hospital, Charlotte, North Carolina, July 22, 2008.

• Invited speaker, Complications after Hematopoietic Stem Cell Transplantation.

Tennessee Society of American Medical Technologists, Memphis, Tennessee, September 29, 2007.

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• Invited speaker, Complications after Hematopoietic Stem Cell Transplant. Mid-South

Oncology Advanced Practice Association, Memphis, Tennessee, June 12, 2007.

• Invited speaker, Ethical Issues in Pediatric Clinical Research. Beth Sholom Synagogue, Memphis, Tennessee, February 25, 2007.

• High dose defibrotide as therapy for pediatric patients with veno-occlusive disease of the

liver. Authors: G.A. Hale, R. Madden, K.A. Kasow, J.P. Woodard, W.H. Leung, R.C. Barfield, U. Yusuf, E.M. Horwitz, R. Handgretinger. Presented at the American Society of Hematology 48th Annual Meeting and Exposition, Orlando, FL; December 2006.

• Mismatched family member donor transplantation for patients with refractory

hematologic malignancies: long-term follow-up of a prospective clinical trial. Authors: G.A. Hale, K.A. Kasow, R. Madden, U. Yusuf, E. Horwitz, R. Barfield, J Woodard, W.H. Leung, K. Srivastava, R. Handgretinger. Presented at the American Society of Hematology 48th Annual Meeting and Exposition, Orlando, FL; December 2006.

• Invited speaker, Ethical Issues in Pediatric Clinical Research. Beth Sholom Synagogue,

Memphis, Tennessee, June 18, 2006.

• Obstructive sleep apnea in infants with malignant infantile osteopetrosis. Authors: Dawn Tottenham, BFA, Sreekrishna Donepudi, MD, Rose Mary S. Stocks, Pharm D, MD, Kimberly A. Kasow, DO, Sue C. Kaste, DO, Edwin M. Horwitz, MD, PhD, Jerome W. Thompson, MD. Presented at the American Society of Pediatric Otolaryngology, Chicago, IL; May 21, 2006.

• Sue C. Kaste, Kim A. Kasow, Edwin M Horwitz. Bone mineral density determination in

malignant infantile osteopetrosis. Submitted for the Society for Pediatric Radiology and the European Society of Paedatric Radiology’s Fifth Conjoint Meeting, Montreal, Quebec, Canada, May 18-20, 2006.

• Haploidentical transplantation for children with refractory hematologic malignancies.

Authors: G. Hale, X. Chen, E. Benaim, P. Woodard, K. Kasow, E. Horwitz, W. Leung, U. Yusuf, R. Barfield, R. Hayden, J. Knowles, F. Behm, S. Shurtleff, V. Turner, R. Handgretinger. Presented at the 2006 EMBT meeting. Hamburg, Germany; March 2006.

• A review of the use of topotecan for mobilization of peripheral blood stem cells in

autologous hematopoietic stem cell transplantation. Authors: Katherine Pring, Gregory Hale, Raymond Barfield, Ed Horwitz, Kimberly Kasow, Wing Leung, Paul Woodard, Usman Yusuf, Rupert Handgretinger. Poster presented at the 2006 BMT Tandem Meetings (IBMTR/ASBMT). Honolulu, Hawaii; February 19, 2006.

• Invited speaker, Children with Osteopetrosis: Curing and Improving Lives. Transplant

and Gene Therapy Seminar Series. St. Jude Children’s Research Hospital, Memphis, Tennessee, January 25, 2006.

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• Invited speaker, Children with Osteopetrosis: Curing and Improving Lives. University of

Minnesota. Minneapolis, Minnesota, October 25, 2005.

• Invited speaker, Marble Bones: Strengthening Our Knowledge about Osteopetrosis. Guest Lecturer. Children’s Hospital, Columbus, Ohio, May 26, 2005.

• Invited speaker, Marble Bones: Strengthening Our Knowledge about Osteopetrosis.

Transplant and Gene Therapy Seminar Series. St. Jude Children’s Research Hospital, Memphis, Tennessee, May 18, 2005.

• Invited speaker, A “Quick” Review of Pediatric Hematology-Oncology. Second year

medical students, Kirksville College of Osteopathic Medicine, Kirksville, Missouri, April 16, 2004.

• Invited speaker, Hematopoietic Stem Cell Transplant: An Overview; KCOM Pediatrics

Club, Kirksville College of Osteopathic Medicine, Kirksville, Missouri, April 16, 2004. • Usman Yusuf, Gregory Hale, Paul Woodard, Ely Benaim, Kimberly Kasow, Edwin

Horwitz, Wing Leung, Deo Kumar Srivastava, Rupert Handgretinger, Randy Haden. Cidofovir is safe and effective in the treatment of adenoviral infection in pediatric hematopoietic stem cell transplantation. Blood. (Abstract #2232, poster presentation American Society Hematology [ASH] Annual Meeting) 2004.

• Fragile! Children With Malignant Osteopetrosis Require Expert Care: Guidelines For

Nursing Staff. Authors: Marty Steed, RN, Kimberly Kasow, DO. Presented at APON (American Pediatric Oncology Nursing) Convention. Philadelphia, PA; October 8-11, 2003.

• Invited speaker, Hematopoietic Stem Cell Transplant: An Overview. Grand Rounds,

Illinois Children’s Hospital, Peoria, Illinois, September 4, 2003.

• Invited speaker, Osteopetrosis, Lecturer for Continuing Education, Conexão Médica, São Paulo, Brazil, March 19, 2003.

• Invited speaker, Osteopetrosis, Seminar, Hospital de Clinicas da Universidade Federal

Do Paraná, Curitiba, Brazil, March 18, 2003.

Teaching Record:

• Lecturer, Understanding the Challenges of Hematopoietic Stem Cell Transplant. Pediatric Hematology/Oncology Educational Series, University of North Carolina, Chapel Hill, North Carolina, January 27, 2011.

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• Lecturer, Pediatric BMT: The Past, Present, and Future. Pediatric BMT Nursing Core, University of North Carolina, Chapel Hill, North Carolina, July 16, 2010.

• Lecturer, The Challenges of Hematopoietic Stem Cell Transplantation. Pediatric BMT Nursing Core, University of North Carolina, Chapel Hill, North Carolina, July 16, 2010.

• Lecturer, Late Effects after Hematopoietic Cell Transplantation. Pediatric BMT Nursing Core, University of North Carolina, Chapel Hill, North Carolina, July 16, 2010.

• Lecturer, FACT and the Quality Management Program at UNC. Pediatric BMT Nursing Core, University of North Carolina, Chapel Hill, North Carolina, July 16, 2010.

• Lecturer, Multi-Center, Open Label, Randomized Trial Comparing Single versus Double Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients with High Risk Leukemia and Myelodysplasia- Phase III Study, BMT CTN Protocol 0501. Presented to the UNC BMTU and Pediatric Hematology/Oncology Nurses, University of North Carolina Health Care, Chapel Hill, North Carolina, June 14, 15, 17, 2010.

• Lecturer, The Basics of Hematopoietic Stem Cell Transplantation. Presented monthly to the pediatric residents serving on the pediatric hematology/oncology in-patient service and to an osteopathic medical student rotating through UNC, University of North Carolina, Chapel Hill, North Carolina, 2009-2010.

• Lecturer, Welcome to the Challenges of Hematopoietic Stem Cell Transplantation. Presented to the PICU fellows and faculty members at the University of North Carolina Health Care, Chapel Hill, North Carolina, January 14, 2010.

• Lecturer, Late Effects After Hematopoietic Cell Transplantation with Cammie Moore, MSN, RN, CPNP, CPON, BMT Nursing Core Series, UNC-CH, Chapel Hill, North Carolina, October 30, 2009.

• Lecturer, FACT and the Quality Management Program at UNC, BMT Nursing Core Series, UNC-CH, Chapel Hill, North Carolina, October 30, 2009.

• Lecturer, Pediatric BMT: The Clinical Research Program, BMT Nursing Core Series, UNC-CH, Chapel Hill, North Carolina, October 30, 2009.

• Mentorship, clinical mentor for LeShara Fulton who was awarded a UNC graduate training program grant in translational medicine. This program is sponsored by the Howard Hughes Institute. Her project is to evaluate the function of Coronin 1A in the migratory capacity of donor T-lymphocytes. Grant was awarded and began July 2009.

• Lecturer, Curing and Improving the Lives of Children with Malignant Infantile Osteopetrosis (MIOP). Fellow’s Rounds, St. Jude Children’s Research Hospital, Memphis, Tennessee, October 20, 2008.

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• Lecturer, Curing and Improving the Lives of Children with Malignant Infantile Osteopetrosis (MIOP). BMT course. St. Jude Children’s Research Hospital, Memphis, Tennessee, October 13, 2008.

• Lecturer, The Basics of Hematopoietic Stem Cell Transplantation. Pediatric Oncology

Education Lunch and Learn Series. St. Jude Children’s Research Hospital, Memphis, Tennessee, July 8, 2008.

• Lecturer, Late Effects after Hematopoietic Stem Cell Transplantation. Fellow’s Rounds.

St. Jude Children’s Research Hospital, Memphis, Tennessee, February 25, 2008.

• Lecturer, Morbidity and Mortality Conference: EBV of the CNS after Cord Transplant. St. Jude Children’s Research Hospital, Memphis, Tennessee, January 31, 2008.

• Lecturer, Curing and Improving the Lives of Children with Osteopetrosis: The Marble

Bone Disease. BMT course. St. Jude Children’s Research Hospital, Memphis, Tennessee, November 19, 2007.

• Lecturer, Acute and Chronic GVHD What One Needs to Know to Survive BMT.

Fellow’s Rounds. St. Jude Children’s Research Hospital, Memphis, Tennessee, November 5, 2007.

• Lecturer, The Basics of Hematopoietic Stem Cell Transplantation. Pediatric Oncology

Education Lunch and Learn Series. St. Jude Children’s Research Hospital, Memphis, Tennessee, July 3, 2007.

• Lecturer, Hematopoietic Stem Cell Transplant: An Overview. Resident’s Noon Lecturer

Series. LeBonheur Children Medical Center. Memphis, Tennessee, March 12, 2007.

• Lecturer, Curing and Improving the Lives of Children with Osteopetrosis: The Marble Bone Disease. BMT course. St. Jude Children’s Research Hospital, Memphis, Tennessee, November 7, 2006.

• Lecturer, Hematopoietic Stem Cell Transplant: An Overview. Pediatric Oncology

Education Lunch and Learn Series. St. Jude Children’s Research Hospital, Memphis, Tennessee, July 12, 2006.

• Lecturer, Curing and Improving the Lives of Children with Osteopetrosis: The Marble

Bone Disease. BMT course. St. Jude Children’s Research Hospital, Memphis, Tennessee, May 22, 2006.

• Mentorship, Jennifer Krueger, Pediatric Oncology Education Program, Department of

Hematology/Oncology, St. Jude Children’s Research Hospital, 2006.

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• Lecturer, Acute and Chronic GVHD: What One Needs to Know to Survive BMT. Advanced BMT course. St. Jude Children’s Research Hospital., Memphis, Tennessee, December 6, 2005.

• Lecturer, Osteopetrosis: The Marble Bone Disease. BMT Course. St. Jude Children’s

Research Hospital, Memphis, Tennessee, October 11, 2005.

• Lecturer, Hematopoietic Stem Cell Transplantation for Non-Malignant Diseases. Fellow’s Rounds. St. Jude Children’s Research Hospital, Memphis, Tennessee, September 26, 2005.

• Lecturer, WASHAP and WASSCT, Lunch and Learn Series, Stem Cell Transplant

Program, St. Jude Children’s Research Hospital, Memphis, Tennessee, September 7, 2005.

• Lecturer, Morbidity and Mortality Conference, St. Jude Children’s Research Hospital,

Memphis, Tennessee, June 2, 2005.

• Lecturer, ALSCID. Leukemia/Lymphoma Conference, St. Jude Children’s Research Hospital, Memphis, Tennessee, May 31, 2005.

• Lecturer, OPBMT and OPBMT2. Leukemia/Lymphoma Conference, St. Jude Children’s

Research Hospital, Memphis, Tennessee, May 24, 2005.

• Lecturer, Ethical Issues in 2nd Allogeneic Transplant for Relapsed Leukemia, invited panel participant, Leukemia/Lymphoma Conference, St. Jude Children’s Research Hospital, Memphis, Tennessee, February 8, 2005.

• Lecturer, Coping with Death, Pediatric Advance Life Support Course, St. Jude Children’s

Research Hospital, Memphis, Tennessee, January 12, 2005.

• Mentorship, Erin King, Pediatric Oncology Education Program, Department of Hematology/Oncology, St, Jude Children’s Research Hospital, 2005

• Lecturer, Osteopetrosis: Strengthening Our Knowledge about Marble Bones. Bone

Marrow Transplant Course, St. Jude Children’s Research Hospital, Memphis, Tennessee, October 4, 2004.

• Lecturer, Children with Special Healthcare Needs, Pediatric Advance Life Support

Course, St. Jude Children’s Research Hospital, Memphis, Tennessee, September 22, 2004.

• Lecturer, Osteopetrosis: Strengthening Our Knowledge about Marble Bones. Lunch and

Learn Series, St. Jude Children’s Research Hospital, Memphis, Tennessee, September 8, 2004.

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• Lecturer, Lung Biopsies After Transplantation: Tumor Board, St. Jude Children’s Research Hospital, Memphis, Tennessee, August 20, 2004.

• Invited speaker, Hematopoietic Stem Cell Transplant: An Overview; KCOM Pediatrics

Club, Kirksville College of Osteopathic Medicine, Kirksville, Missouri, April 16, 2004.

• Lecturer, Osteopetrosis: Strengthening Our Knowledge about Marble Bones. Bone Marrow Transplant Course, St. Jude Children’s Research Hospital, Memphis, Tennessee, April 13, 2004.

• Lecturer, Children with Special Healthcare Needs, Pediatric Advance Life Support

Course, St. Jude Children’s Research Hospital, Memphis, Tennessee, March 25, 2004.

• Lecturer, Coping with Death, Pediatric Advance Life Support Course, St. Jude Children’s Research Hospital, Memphis, Tennessee, February 27, 2004.

• Lecturer, Coping with Death, Pediatric Advance Life Support Course, St. Jude Children’s

Research Hospital, Memphis, Tennessee, December 12, 2003.

• Participant, First International Symposium on Osteopetrosis: Biology and Therapy, National Institutes of Health, October 23-24, 2003.

• Lecturer, Coping with Death, Pediatric Advance Life Support Course, St. Jude Children’s

Research Hospital, Memphis, Tennessee, October 8, 2003.

• Lecturer, Marble Bones: Strengthening the Knowledge about Osteopetrosis, Bone Marrow Transplant Course, St. Jude Children’s Research Hospital, Memphis, Tennessee, October 7, 2003.

• Lecturer, Children with Special Healthcare Needs, Pediatric Advance Life Support

Course, St. Jude Children’s Research Hospital, Memphis, Tennessee, June 20, 2003.

• Lecturer, Marble Bones: Strengthening the Knowledge about Osteopetrosis, Seminar, St. Jude Children’s Research Hospital, Memphis, Tennessee, June 2, 2003.

• Lecturer, Coping with Death, Pediatric Advance Life Support Course, St. Jude Children’s

Research Hospital, Memphis, Tennessee, May 29, 2003.

• Lecturer, Children with Special Healthcare Needs, Pediatric Advance Life Support Course, St. Jude Children’s Research Hospital, Memphis, Tennessee, April 24, 2003.

• Lecturer, Marble Bone Disease: Osteopetrosis, Bone Marrow Transplant Course, St. Jude

Children’s Research Hospital, Memphis, Tennessee, April 15, 2003. • Lecturer, Marble Bones: Strengthening the Knowledge about Osteopetrosis, Seminar,

Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, April 9, 2003.

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• Lecturer, Osteopetrosis, Bone Marrow Transplant Course, St. Jude Children’s Research

Hospital, Memphis, Tennessee, November 25, 2002.

• Lecturer, Coping with Death, Pediatric Advance Life Support Course, St. Jude Children’s Research Hospital, Memphis, Tennessee, September 25, 2002.

• Lecturer, Osteopetrosis, Leukemia/Lymphoma Conference, St. Jude Children’s Research

Hospital, Memphis, Tennessee, July 30, 2002.

• Lecturer, Osteopetrosis, Lunch and Learn Series, Stem Cell Transplant Program, St. Jude Children’s Research Hospital, Memphis, Tennessee, July 10, 2002.

• Lecturer, Osteopetrosis, Foundations in Pediatric Hematopoietic Stem Cell

Transplantation, St. Jude Children’s Research Hospital, Memphis, Tennessee, September 2001.

• Lecturer, Infant ALL and Haploidentical Transplant, Leukemia/Lymphoma Conference,

St. Jude Children’s Research Hospital, Memphis, Tennessee, February 27, 2001.

• Lecturer, Pure Red Cell Aplasia, Fellow’s Rounds, St. Jude Children’s Research Hospital, Memphis, Tennessee, February 14, 2000.

• Lecturer, Colon Cancer, Tumor Board, St. Jude Children’s Research Hospital, Memphis,

Tennessee, February 11, 2000.

Grants: NC TraCS Institute $10K Grant Kasow (PI) 2/1/10-1/31/11 Through their eyes: Understanding the young sibling hematopoietic stem cell donor

experience and understanding the experiences of the young non-donor sibling of hematopoietic stem cell transplant recipients.

The specific aim of this study is to explore and describe the meaning of the sibling donor’s and non-donor sibling’s childhood/young adult experiences through his/her own words and recollections.

Role: PI Presidential Grant from the Greenwall Foundation ($12,032) Kasow (PI) 6/1/10-5/31/11 Though their eyes: Understanding the young matched sibling hematopoietic stem cell donor

experience The goal of this study is to further understand the experiences of matched sibling

hematopoietic stem cell donor in hopes of altering care to benefit the donor. Role: PI

Laboratory Training for Clinical Oncologists (NIH funded), Michael Kastan, MD, PhD, PI;

Grant number 2 T32 CA70089-06A1 (2002-2003). This grant covered my salary for my last

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year of fellowship. Professional Services:

2011-present National Marrow Donor Program Council, Vice President 2010 Transplant Center Reviewer, National Marrow Donor Program DVD,

“Super Sam versus the Marrow Monsters: 2010-present University of North Carolina Oncology Pharmacy and Therapeutics

Subcommittee, member 2009-present BMT Quality Improvement Committee, University of North Carolina at

Chapel Hill, Chapel Hill, North Carolina Transplant Quality Assurance and Quality Improvement Program Officer,

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 2009-present UNC HLA Review Committee, University of North Carolina at Chapel

Hill, Chapel Hill, North Carolina 2009-present UNC Oncology Safety Committee, University of North Carolina at Chapel

Hill, Chapel Hill, North Carolina 2009-present UNC Radiation Injury Treatment Network Committee, University of

North Carolina, Chapel Hill, North Carolina 2008-2009 Transplant Quality Improvement Committee, St. Jude Children’s Research

Hospital, Memphis, Tennessee 2007-2009 Transfusion Committee, St. Jude Children’s Research Hospital, Memphis,

Tennessee 2007-present Foundation for the Accreditation of Cellular Therapy (FACT), inspector 2008-present, FACT Facility Relations Committee 2009-present, FACTWeb Committee, Vice-Chair Summer 2007 Family Camp for Hematology-Oncology Week, Camp Hopewell, Camp

Physician, Oxford Mississippi 2006-2009 Privileges granted in the Methodist Healthcare System. 2006-2009 HSCT Clinic- CIS Reengineering Committee, St. Jude Children’s

Research Hospital, Memphis, Tennessee Summer 2006 Family Camp for Hematology-Oncology Week, Camp Hopewell, Camp

K:\shared\development\Danielle\Faculty\CVs\Peds Hematology-Oncology\CV_Kim Kasow_Apr11.doc

Physician, Oxford, Mississippi 2005-present Osteopathic Institute of the South – adjunct clinical faculty member 2005-2009 Critical Care Committee, St. Jude Children’s Research Hospital,

Memphis, Tennessee 2005-2008 Clinical liaison for the development of the Transplant Laboratory

database, St. Jude Children’s Research Hospital, Memphis, Tennessee Summer 2005 Family Camp for Hematology-Oncology Week, Camp Hopewell, Camp

Physician, Oxford, Mississippi 2003-2008 Member, Board of Directors, Beth Sholom Synagogue, Memphis,

Tennessee 2004-2005 Secretary, Executive Board, Beth Sholom Synagogue, Memphis,

Tennessee Summer 2004 Family Camp for Hematology-Oncology Week, Camp Hopewell, Camp

Physician, Oxford, Mississippi Summer 2003 Family Camp for Hematology-Oncology Week, Camp Hopewell, Camp

Physician, Oxford, Mississippi Summer 2002 Family Camp for Hematology-Oncology Week, Camp Hopewell, Camp

Physician, Oxford, Mississippi 2002-2008 Youth Commission Chairman, Beth Sholom Synagogue, Memphis,

Tennessee 2002-2008 Clinical Informatics Oversight Committee, St. Jude Children’s Research

Hospital, Memphis, Tennessee 2001-2008 Youth Commission Member, Beth Sholom Synagogue, Memphis,

Tennessee

Summer 2001 Family Camp for Hematology-Oncology Week, Camp Hopewell, Camp Physician, Oxford, Mississippi

Professional Society Memberships:

American Society for Blood and Marrow Transplantation American Society of Pediatric Hematology/Oncology Children’s Oncology Group

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Pediatric Blood and Marrow Transplant Consortium Certification: 1997 Diplomate, National Board of Osteopathic Medical Examiners (7/1/1997,

28471) 1999 Diplomate, American Board of Pediatrics (10/19/1999, 067548) 1999 Pediatric Advanced Life Support Provider, recertification 2007 2000 Instructor, Pediatric Advanced Life Support Provider, recertification 2006 2000 Basic Life Support Provider, recertification 2008 2004 Diplomate, American Board of Pediatrics, Sub-Board of Pediatric

Hematology-Oncology (11/15/04, 652189)

Human Subjects Research Training:

• Collaborative Institutional Training Initiative (CITI), 2008

• Protecting Study Volunteers in Research, University of Rochester, 2000

State Licensure: North Carolina License number 2009-00269 (3/3/2009- present: active) Tennessee License number: DO 0000001372 (9/27/2000- 4/30/2010: inactive) Ohio License number: 34.006703 (8/8/1997 – 10/01/2002: inactive)

Clinical Investigation: Principal Investigator

OPBMT: Allogeneic Hematopoietic Stem Cell Transplantation Utilizing Purified CD34+ Cells for Children Affected with Osteopetrosis: A Pilot Study. Principal Investigator of Record: Edwin Horwitz, MD, PhD; Principal Investigator: Kimberly Kasow, DO (opened 2002; closed August 2003) (IND 10221).

OPBMT2: Allogeneic Hematopoietic Stem Cell Transplantation for Children Affected with Malignant Osteopetrosis: A Pilot Study. Principal Investigators: Kimberly Kasow, DO and Edwin Horwitz, MD, PhD (opened July 2004; closed March 2009) (IND 10221). ALSCID: Transplantation of Highly Purified Haploidentical CD133+ Hematopoietic Cells in Children with Severe Combined Immunodeficiency Syndrome. Principal Investigator of Record: Kimberly Kasow, DO, Principal Investigator: John M. Cunningham, MD (re-opened October 2006; closed August 2007) (IDE 11118). WASHAP: Haploidentical Stem Cell Transplantation for Pediatric Patients with Wiskott-

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Aldrich Syndrome: A Pilot Study. Principal Investigator: Kimberly Kasow, DO (opened May 2005; closed March 2009) (IDE 12305). WASSCT: Clinical Practice Plan: Bone Marrow Transplantation Using Matched Sibling Donors or Matched Unrelated Donors For Pediatric Patients With Wiskott-Aldrich Syndrome. Principal Investigator: Kimberly Kasow, DO (opened July 2005, PI until left institution 3/09). BKAMON: Prospective Real-Time PCR Monitoring of BK Virus and Adenovirus in the Urine and Blood of Allogeneic Stem Cell Transplant Recipients. Principal Investigator: Kimberly Kasow, DO (opened 2007, PI until left institution 3/09). SAAHAP: Hematopoietic Stem Cell Transplantation (HSCT) from Partially Matched Family Donors for Patients with Refractory Severe Aplastic Anemia or Refractory Cytopenias: A Pilot Study. Principal Investigator: Kimberly Kasow, DO (opened October 2005, PI Dec 2007, closed May 2009). PALSCT: Phase I Study of the Use of Palifermin in Pediatric Research Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. Principal Investigator: Kimberly Kasow, DO (opened 2007, PI until left institution 3/09).

Journal Reviewer:

Bone Marrow Transplantation Biology of Blood and Marrow Transplantation

Reflective Statement: During my first faculty position at St. Jude Children’s Research Hospital, my clinical research interests have included allogeneic hematopoietic stem cell transplantation for pediatric disorders including children with non-malignant diseases, such as osteopetrosis, and immunodeficiencies, such as Wiskott-Aldrich syndrome. Through treating children with malignant infantile osteopetrosis, I have been able to gain knowledge regarding this rare disease that has led to a treatment protocol using a reduced intensity conditioning regimen, an invitation to the First International Symposium on Osteopetrosis, published manuscripts, and most recently, the opportunity to present my research findings at the 2009 BMT Tandem meeting in Tampa, Florida. I also believe that supportive care plays a major role in outcomes after transplantation. Therefore, I have been the primary investigator for a clinical research study using palifermin in the pediatric setting. This protocol is continuing to enroll patients and will hopefully soon finish accrual. As a clinical investigator, I try to learn from my patients while providing the best medical care possible. I have been involved in several clinical research protocols involving partially matched family member transplant, for which I have been the primary investigator (as noted above). I believe that we should continue to strive to learn from our patients and encourage clinical research whenever possible, whether it be for therapeutic, supportive, or data collection purposes and using resources, internal and external, as available to participate in studies in order for the field of pediatric hematopoietic stem cell transplantation to advance

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safely. Part of my role as a physician is to be an educator to my patients, families, and staff. Through this philosophy as noted through the lectures I have provided, I participate as a regular educator in the BMT courses at St. Jude for the nursing staff, I present a lecture regarding the basic concepts of hematopoietic stem cell transplantation to the Pediatric Oncology Education (POE) students each summer, and I have given formal and informal lectures and provided teaching didactics to the pediatric hematology/oncology fellows at St. Jude Children’s Research Hospital. During my clinical visits with my patients, I also provide education, whether it is their first meeting with me or an annual visit. Education provides the tools to make knowledgeable decisions. My vision for the future is to build a strong pediatric bone marrow transplant program at the University of North Carolina with the help of the staff currently present and utilizing the foundation that has been set. I believe that it will be important to also develop a strong working relationship with those involved in the collection and processing facilities. Engaging community physicians and other pediatric hematologist/oncologists will be important as we build, and educating the staff as changes occur to provide the best medical care possible with consistency will be important for all involved in the program. Building can begin as I learn the foundation and the team works together to provide excellent outcomes for pediatric patients undergoing hematopoietic stem cell transplantation at UNC.