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Reglarea activittii

cardiovasculare

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AortaVene cave

Artere

Vene

PresiunePresiunePresiunePresiune

arterialarterialarterialarterial

RezistenRezistenRezistenRezistena periferica periferica periferica periferic

InputInputInputInput OutputOutputOutputOutput

InputInputInputInput OutputOutputOutputOutput

SistemSistemSistemSistemneuroneuroneuroneuro----endocrinendocrinendocrinendocrin

AferenteAferenteAferenteAferente EferenteEferenteEferenteEferente

Autoreglare

(intrinsec)

Reglareextrinsec

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Autoreglarea intrinseca activittii cardiace

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Relatia lungime-tensiune la nivelul fibrei miocardice

Lungime sarcomer (um)

Tensiune(%Tm

sx)

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Preparatul de inim izolat Starling

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Relatia volum btaie-presiune telediastolic

(relatia Frank Starling)

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Organizarea sistemului circulator

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Relatia volum btaie-presiune telediastolic

(relatia Anrep)

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Relatia frecvent cardiac - fort contractil

(efectul Bowditch)

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Relatia frecvent cardiac - fort

contractil (efectul Bowditch)

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Dinamica fenomenelor din cadrul

cuplului electro-contractil

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Reglarea intrinsec aactivittii circulatiei

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Autoreglarea fluxului coronarian

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Autoreglarea miogen si dependent de endoteliu

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Hiperemia reactiv

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Adenozina n reglarea circulatiei

Adenozina

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Organizarea reflexelor cardiovasculare

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Receptorii cardiovasculari

Receptorii arteriali1. Mecanoreceptori2. Chemoreceptori

Receptorii cardiaci1. Mecanoreceptori veno-atriali mielinizai

2. Mecanoreceptori veno-atriali nemielinizai3. Baroreceptori coronarieni4. Chemoreceptori

Ali receptori1. Receptorii pulmonari de distensie

2. Receptorii din muchii striai3. Ali receptori extracradiaci

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Baroreceptorii arteriali

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Comportamentul baroreceptorilor vasculari

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Comportamentul baroreceptorilor vasculari

Fibre tip AFibre tip AFibre tip AFibre tip A

Fibre tip CFibre tip CFibre tip CFibre tip C

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Receptorii cardiaci

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Sincopa neurocardiogenTilt-testul (testul mesei nclinate)

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Angina pectoral i durerea referit

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Centrii vasomotori bulbo-pontini

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Cile eferente

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Sistemul nervos intrinsec cardiac

Olshanski B. et al. Progr Cardiovasc Dis 2005, 48: 57-78