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Curriculum vitae: Prof. Dr. med. Hanspeter E. Killer, 25.8.1951

Kantonsspital Aarau, Augenklinik 5001 Aarau. Tel. 062 838 50 03 Mail: killer@ksa.ch

Studies

Studies in computerlinguistics and mathematics University of Zürich Medical school University of Zürich Fellowship in Neuro-Ophthalmology Albert Einstein College of Medicine, New York

Current position Chair of department of Ophthalmology, Kantonsspital Aarau

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Awards and honors 1987 Award for excellent thesis of University of Zürich 1987 (Experimental thesis on

reinnervation of motor endplates after autologous muscle transplantation.)

1993 Wahl in die North American Society of Neuro-Ophthalmology

1994 Gründungsmitglied der Schweizerischen Dystonie-Gesellschaft Seither ständiger ärztlicher Beirat

1995 Aufnahme in die ”International Strabismus Society”

1995 2001 Section Editor for European abstracts im J Neuro-Ophthalmology (offizielles Organ der amerikanischen Gesellschaft für Neuroophthalmologie)

1995 Mitglied der Strabismuskommission der SOG

1998 Poster award of the Swiss Ophthalmological Society for best scientific poster

1999 Invited visiting professor Albert Einstein College of Medicine, New York

2001 Member des internationalen editorial boards des U.S. Chinese J of Ophthalmology

2002 – 2006 Präsident der Strabismuskommission der SOG

2000 März, Ernennung zum Fellow of the American Society of Neuro- Ophthalmology

2007 Associate professor University of Basel

2007 Alfred Vogt medal (Highest award for research in Ophthalmology in Switzerland)

2007 Faculty of 1000 (Global leaders expert knowledge) for the paper: Cerebrospinal fluid dynamics between the intracranial and the subarachnoid space of the optic nerve.Is it always bidirectional? Brain 2007 Feb 130(Pt 2):514-20

2008 Member of the research committee of the EUNOS

2009 Visiting professor Johns Hopkins University, Baltimore

2009 Visiting professor New York Eye and Ear Infirmary

2009 Editorial member of J Frontiers of Neuro-Ophthalmology

2010 Visiting professor lecture New York University March

2010 Visiting professor lecture Mayo Clinic, Rochester, USA

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2011 Consultant for NASA microgravity team

2011 Consultant for glaucoma think tank New York 2012 Invited member to von Graefe society

2013 Faculty member for the fourth annual “Managing Glaucoma: Beyond intraocular pressure, San Francisco

2013 Consultant NASA VIIP RCAP, Houston, Texas

2014 Lowi medal from ANZGIG, Perth, Australia

2014 Consultant for ESA 2014 Poster prize from SOG for best scientific poster

2014 Reviewer and consultant for International Life Sciences Research Announcement [2014_ILSRA, ESA, NASA] Washington

2015 Guest speaker: 66th International Astronautical Congress, 12 – 16 October 2015, Jerusalem, Israel

2015 Member of the Forschungsrat Kantonsspital Aarau

2015 Guest speaker: Congress of Belgium glaucoma society, Brussels

2016 Consultant for glaucoma think tank New York June 2016

2016 Invited member of intraocular and interacranial pressure summit, Peking

2016 Preis der Gesellschaft für Neurowissenschaften der Schweiz für besten Poster

2017 Guest professorship Tongren Hospital / Peking university Peking China

2017 Honory Member AISG Rom

Fields of research Optic nerve Glaucoma Cerebrospinal fluid dynamics and content Strabismus

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Reviewer for American Journal of Ophthalmology

Medical Science Monitor

Indian journal of cancer

IOVS (Investigative ophthalmology and visual science)

Ophthalmologica

Klinische Monatsblätter Augenheilkunde

Acta Neurochirurgica

Experimental Eye Research

J Neuroimaging

Br J Ophthalmology

Clinical and Experimental Ophthalmology

Critical care

J Glaucoma

Ophthalmology

J Histology and Histopathology

J Anesthesia

Restorative Neurology and Neuroscience

Plos One

Acta Ophthalmologica

Progress in Retinal and Eye Research

Graefe's Archive for Clinical and Experimental

Ophthalmology

Journal of Neuro-Ophthalmology: the official journal of the North American

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Neuro- Ophthalmology Society U.S. Chinese J of Ophthalmology

Grants

Emilia Guggenheim-Schnurr Stiftung

Freie Akademische Gesellschaft (Fonds zur Förderung von Lehre und Forschung)

De Bernardi Fond

Helmut Horten Stiftung

Messerli Stiftung

KSA Forschungsrat

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Publications with peer review

1. H.E. Killer and M. Müntener. Time course of the regeneration of the endplate zone after autologous muscle transplantation. Experientia 1986, 42: 301-302 2. H.E. Killer, F.X. Borrouat, B. Blumer, A. Jauch. Corneal penetration of diclofenac from a

fixed combination of diclofenac-gentamicin eye drops. J Cataract and Refract Surgery 1998;24: 1365-1370.

3. H.E. Killer and K. Hess. Natural history of radiation induced brachial plexopathy compared with surgically treated patients. J Neurol 1990; 237: 247-50.

4. H.E. Killer. Schweiz. Rundschau Sehstörungen bei normalem Augenstatus. für Med. 1990; 9 (49): 1538-1540. B. Blumer, R.M. Burde. Pseudotumor cerebri. 5. H.E. Killer,Verlaufsparameter und Therapiemodalitäten. Klin

6. B. Blumer und H.E. Killer. Akute Amaurose bei EPH Gestose. Klein. Mbl. Augenheilk. 1993: 202: 369-372.

7. H.E. Killer, B. Blumer and M. Mayers. Comparison of anti-inflammatory potency and local tolerance of diclofenac and indomethacin eye dropa in the postoperative management of patients undergoing ECCE with PCL.Ocular immunology and inflammation 1993, 1(3): 211- 217.

8. L. Risch, B. Blumer, H. Laeng, A. Forrer, H.E. Killer, A. Huber. Rapid diagnosis of intraocular neoplasia using flow cytometry. Blood. 1994; 94: 10 Supp I, 253b.

9. H.E. Killer. Acute ectropion following botulinumtoxin injections for the treatment of blepharospasm after bilateral facial neurectomies. Neuro- Ophthalmol 1993; 13 (1): 1-3.

10. H.E. Killer, D.C Matzkin, D.C. Sternman, C. Jahre and R.M. Burde .Intracavernous carotid aneurysm as a rare case of isolated sixth nerve palsy in an eight year old child.Neuro-Ophthalmol 1993; 13 (3): 147-150.

11. H.E. Killer, B. Blumer, A. Bähler. Approach to traumatic sixth nerve palsy with botulinumtoxin A. Neuro-Ophthalmol 1994; 14 (6): 355-358.

12. H.E. Killer und O. Job. Differentialdiagnostische Überlegungen zur Retrobulbärneuritis. Nervenarzt 1996; 67: 815-820.

13. H.E. Killer, O. Job, A. Forrer. Retrobulbärneuritis – Diagnostik und Differentialdiagnose. Schweiz. Rundschau für Med. 1996; 95 (17) : 554-558.

14. K. Landau, H.E. Killer. Radiation damage. Neurology 1996; 46: 889

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15. H.E. Killer, A.M. Eggmann, A. Forrer. Serous retinal detachment with disc swelling of the optic disc after a bee sting. Neuro-Ophthalmol 1997; 18 (3): 153-155.

16. Mironow, H.E. Killer. Transvenous embolization of dural fistulas. Klinische Neuroradiologie 1997; 7 (3):105-112.

17. H.E. Killer, A. Forrer, B. Blumer. Nonarteritic posterior ischemic optic neuropathy treated with optic nerve sheath decompression. Report of two cases.Neuro-Ophthalmol 1998; 19 (2): 101-106.

18. H.E. Killer, B. Blumer and O.N. Rüst. Avulsion of the optic disc after a blow to swimming goggles. J Ped and Strab 1999; 36 (2): 92-93.

19. H.E. Killer, R.H. Laeng and P. Groscurth. Lymphatic capillaries in the meninges of the human optic nerve. J Neuro-Ophthalmol 1999; 19 (4): 222-228

20. H.E. Killer, A. Bähler. Significant immediate and long-term reduction of astigmatism after lateral rectus recession in a divergent Duane syndrome.Ophthalmologica 1999; 213: 209-210.

21. H.E. Killer, R.H. Laeng and P.Groscurth. Lymphatic capillaries in the meninges of the human optic nerve. J Neuro-Ophthalmol 1999; 19 (4): 222-228

22. H.E. Killer, O. Rüst. O. Müller and J. Flammer. Unilateral glaucomatous optic damage in a patient with hemifacial spasm. Ophthalmologica 1999; 213: 273-275.

23. H.E. Killer, A. Huber, C. Portman, A. Forrer and J. Flammer. Bilateral nonarteritic anterior ischemic optic neuropathy in a patient with autoimmunthrombocytopenia.Europ. J Ophthalmol. 2000; 10 (2) 180-182.

24. H.E. Killer, D.J. Holz, H.J. Kaiser and R.H. Laeng. Diplopia, ptosis and hepatitis as presenting signs and symptoms of giant cell arteritis. Br J Ophthalmol 2000; 84, (11): 1319-1320.

25. H.E. Killer. HIV-assoziierte Erkrankungen am visuellen System. Schweizerische R undschau für Medizin Praxis 2000; 89: 1512-1515.

26. H.E. Killer. Anomalous optic disc elevation associated with ultrasonographic evidence of increased subarachnoid fluid. J Neuro- Ophthalmology 2000, 20 (4): 294

27. H.E. Killer, B. Blumer, O. Rüst. Avulsion of the optic disc after a blow to swimming g oggles. J Ophthalmol, Nursing and Technology 2000; 19: 232-233.

28. H.E. Killer, J. Flammer, B. Wicki and R.H. Laeng. Acute asymmetric upper nasal quadrantanopia caused by a colloid cyst in a patient with multiple sclerosis and r etrobulbar neuritis. Am J Ophthalmol 2001; 132: 286-288

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29. H.E. Killer and J. Flammer. Unilateral papilledema in a patient with a fronto parieto occipital arachnoid cyst. Am J Ophthalmol 2001; 132: 589- 91.30.

30. O. Tillman and H.E. Killer. Pseudotumor cerebri in a patient with Goldenhar’s Syndrom. Ophthalmologica 2002; 216:269-299.

31. H.E. Killer, A. Forrer, J. Flammer. Retinal vasospasm in a migrainous patient.Retina 2003; 23:253-4

32. A. Christen, H.E. Killer, B. Stamm, P. Itin. Sekundäre Lues mit okulärem Befall und Schleimhautulcera. – Ein Fallbericht. Praxis: 2003;92: 397-402

33. FM. Sens, H.E. Killer, P. Meyer, Erste Grandientenindex (GRIN)- endoskopische Aufnahmen aus dem Subarachnoidalraum des Nervus opticus. Klin. Mbl. Augenheilk. 2003; 220: 83-85

34. H. E. Killer, R. Hubert, R.H. Laeng, J. Flammer and Peter Groscurth. The arachnoid trabeculae and septae in the subarachnoid space of the human optic nerve: Anatomy and clinical considerations. Br J Ophthalmol. 2003 Jun; 87(6):777-81.

35. H.E. Killer, A. Mironow, J. Flammer. Optic neuritis with marked distension of the optic nerve sheath due to fluid congestion. Br J Ophthamol. 2003; 87: 249

36. M. Bösch, H.E. Killer. Atypical manifestation of neurofibromatosis type 2 in a boy eye. 2005; 19(6): 705-6.

37. H. Kordic, J. Flammer, A. Mironow and H.E. Killer. Posterior non- inflammatory ischemic optic neuropathy (NPION) as a rare complication of blepharoplasty. Ophthalmologica 2005; 219(3f):185-8

38. H.E. Killer, U. Buettner, Multiple visual hallucinations in one individual patient. Ophthalmologica 2005;219;115-118

39. G. Jaggi, R.H. Laeng, M. Müntener and H.E. Killer. The anatomy of the muscle insertion (scleromuscular junction) of the lateral and medial rectus muscle in humans.IOVS 2005;46 (7): 2258-63.

40. K.B. Hatz, M.C. Brodsky and H.E. Killer. Surgical treatment of superior oblique palsy – Efficacy of inferior oblique muscle surgery versus two muscle surgery.Europ J Ophthalmol. 2006; 16: 10-16

41. H.E. Killer et al. The optic nerve: a new window into cerebrospinal fluid composition. Brain. 2006; 129: 1027-1030

42. H.E. Killer et al. Cerebrospinal fluid dynamics between the intracranial – and the subarachnoid space of the optic nerve. Is it always bidirectional?Brain 2007 129(4):1027-1030;

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43. G. Jaggi, A Mironov, A.R. Huber and H.E. Killer. Optic nerve compartment syndrome. Eur J Ophthalmol. 2007 May-Jun; 17(3):454-8.

44. G. Jaggi, Urs Lüthi, Andres Forrer, Paul Hasler and H.E. Killer. Biopsy proven giant cell arteritis: Two cases with complete visual recovery. Is there a time window for successful therapy? Swiss Med Wkly 2007; 137.17-18

45. B. Knecht, P. Groscurth, U. Ziegler, R.H. Laeng and H.E. Killer. Is silicone oil optic neuropathy caused by high intraocular pressure alone? Br J Ophthalmol. 2007 Oct; 91(10): 1293-5.

46. M.C. Grieshaber, B. Dubler, C. Knodel, H.E. Killer, J. Flammer, L. Orgul, Retrobulbar blood flow in idiopathic dilated veins and glaucomato. KlinMonatsblAugenheilkd. 2002: 24:320-3

47. G. P. Jaggi, H.E. Killer. "D2-40 expression demonstrates lymphatic vessel characteristics in the dural portion of the optic nerve sheath". Ophthal. Plast. Reconstr. Surg. 2007 Nov-Dec; 23(6):504-5; author reply 505.

48. Gregor P. Jaggi , Josef Flammer , Andreas R. Huber and H.E. Killer, Lipocaline-like Prostaglandin D Synthase in subretinal fluid of detached retinas and aquosus humor in humans. Retina 2008 Jun;28(6):858-63

49. Gregor P. Jaggi, H.E. Killer; Judith Wirthlin; Anita Eggmann, Andreas Forrer, Early detection of Best`s disease in childhood due to ineffective orthoptic treatment.Klin.Mbl. Augenheilkunde 2008 May; 225(5): 465-8.

50. H.E. Killer, G. Jaggi, J. Flammer, N.R. Miller. Is open-angle glaucoma caused by impaired cerebrospinal fluid circulation: around the optic nerve? Clin Experiment Ophthalmol. 2008 May;36(4):308-11.

51. H.E. Killer, G. Jaggi, N.R. Miller, J. Flammer, P. Meyer. Does immunohistochemistry allow easy detection of lymphatics in the optic nerve sheath? J of Histochem&Cytochem 2008 Dec;56(12):1087-92

52. G.P. Jaggi, H.E. Killer. 'Spontaneous' Periocular Hemorrhage and Macrohematuria. Ophthalmologica 2008 Oct 10; 222(6):422-423

53. H.E. Killer, J. Flammer, N.R. Miller, Glaucoma and cerebrospinal fluid pressure. Ophthalmology 2008 Dec;115(12):2316-7

54. H.E. Killer, N.R. Miller, The role of cerebrospinal fluid pressure in glaucoma pathophysiology: The dark side of the optic disc. J of Glaucoma, 2009 Feb; 18(2):172;

55. R. Sutter, H.E. Killer, S. Bilz, S. Renaud, Cerebral edema and intracranial hypertension in an adult patient with maplesyrup urine disease. Eur J Neurol 2009; 16(3):45

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56. H.E. Killer, Gregor P. Jaggi, Neil R. Miller, Papilledema Revisited: Is its pathophysiology really understood? J of clin and expophthalmol 2009 Jul; 37(5):444-7

57. XiaorongXin, A. Huber, P. Meyer, J. Flammer, N.R. Miller and H.E. Killer. Betatrace protein – L-PGDS – inhibits astrocyte proliferation and astrocyte mitochondrial ATP production in vitro.J MolNeurosci 2009; .2009 Jul 14. [2009 Nov; 39(3):366-71. Epub 2009 Jul 14.

58. X. Xin, B. Fan, H.E. Killer, A. Neutzner, J. Flammer, P. Meyer, Primary cell culture of meningeothelial cells - a new model to study the arachnoid in glaucomatous optic neuropathy Graefes Arch Clin ExpOphthalmol. 2010 Apr 8. [Epub ahead of print]

59. G.P. Jaggi, Harlev, Mickey, Ziegler, Urs Dotan, Shlomo Miller, Neil Miller and H.E. Killer, Optic nerve compartment syndrome. An experimental animal model. Br J Ophthalmol. 2010 Aug;94(8):1088-93.

60. H.E. Killer, G.P. Jaggi, N.R. Miller, Progressive optic neuropathy in idiopathic intracranial hypertension after optic nerve sheath fenestration. J Neuroophthalmol. 2010 Jun; 30(2):205.

61. H.E. Killer, Gregor Peter Jaggi, Neil R. Miller et al. Cerebrospinal fluid dynamics between the basal cisterns and the subarachnoid space of the optic nerve in patients with papilloedema. Brit J Ophthalmol Br J Ophthalmol.2010 Oct 17.

62. G.P. Jaggi, N.R. Miller, J. Flammer, R.N. Weinreb, L. Remonda and H.E. Killer. Optic nerve sheath diameter in normal-tension glaucoma patients.Br J Ophthalmol.2012 Jan;96(1):53-56.

63. S. Berkmann, J. Fandino, S. Zosso, H.E. Killer, L. Remonda, H. Landolt, Intraoperative magnetic resonance imaging and early prognosis for vision after transsphenoidal surgery for sellar lesions. J Neurosurg.2011 Jun 3. [Epub ahead of print]

64. XiaorongXin, A. Huber, P. Meyer, J. Flammer, N.R. Miller and H.E. Killer. Betatrace protein – L-PGDS – inhibits astrocyte proliferation and astrocyte mitochondrial ATP production in vitro.J MolNeurosci 2009; .2009 Jul 14. [2009 Nov;39(3):366-71. Epub 2009 Jul 14.

65. H.E. Killer, G.P. Jaggi, N.R. Miller. Optic nerve compartment syndrome.Acta Ophthalmol. 2011 Aug; 89(5):e472.

66. H.E. Killer, N.R. Miller, R. Weinreb et. al. Cerebrospinal fluid dynamics in normal-tension glaucoma. Brit J Ophthalmol Br J Ophthalmol2012 Apr; 96(4):544-8

67. Bin Fan, Giovanna Bordigari, Josef Flammer, H. E. Killer, Peter Meyer, Albert Neutzner. Meningothelial cells participate in immunological processes in the cerebrospinal fluid.J Neuroimmunology 2012 Mar; 244(1-2):45-50. Epub 2012 Jan 20.

68. Gregor Bauer, H.E. Killer, Andreas Forrer, Andreas R. Huber, Gregor Peter Jaggi,

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Lipocalin-like prostaglandin D synthase (L-PGDS) concentration in aquosus humor in patients with open angle glaucoma: J Glaucoma. 2012 Oct 10

69. H.E. Killer, G.P. Jaggi, Authors' response to Control issues. Br J Ophthalmol. 2013 Jan; 97(1):112. doi: 10.1136/bjophthalmol-2012-302076. Epub 2012 Oct 20.

70. Jatta Berberat, Gregor P. Jaggi, Frederick M. Wang, Luca Remonda and H.E. Killer. Changes in the amygdala produced by viewing strabismic eyes. Ophthalmology 2013 Oct;120(10):2125-9.

71. Thomas H. Mader, C. Robert Gibson, Anastas F. Pass, Andrew G. Lee, H.E. Killer et al, Optic disc edema in an Astronaut after repeat Long- Duration Space Flight.J Neuro- Ophthalmology 2013 Sep;33(3):249-55. doi:

72. H.E. Killer, Production and Circulation of cerebrospinal fluid with respect to the subarachnoid space of the optic nerve. J Glaucoma 2013 Jun- Jul; 22

74. H.E. Killer, Compartment syndromes of the optic nerve and open-angle glaucoma.J. Glaucoma. 2013 Jun-Jul; 22Suppl 5:S19-20. do

75. Li J. Fang L, H.E. Killer, J. Flammer, P. Meyer, A. Neutzner, Meningothelial cells as part of the central nervous system host defence. Biol. Cell. 2013 Jul; 105(7):304-15.

76. J Berberat 1, H.E. Killer, L. Remonda. What is BOLD? J ped ophthalmology 2014 Jan- Feb; 51(1):11

77. H.E. Killer, P. Subramanian, Compartmentalized Cerebrospinal fluid. International Ophthalmology 2014 Winter; 54(1):95-102. doi:

78. Jia Li, Lei Fang, Peter Meyer, H.E. Killer, Josef Flammer, Albert Neutzner, Anti- inflammatory response following uptake of apoptotic bodies by meningothelial cells J Neuroinflammation. 2014 Feb 24; 11(1):35

79. P. Wostyn , V. de Groot, D. van Dam, K. Audenaert, H.E. Killer, P.P. de Deyn, Glaucoma considered as an imbalance between production and clearance of neurotoxins.Invest Ophthalmol Vis Sci. 2014 Aug 26;55(8):5351-2

80. H.E. Killer, Asymmetric papilledema in idiopathic intracranial hypertension –a comment J Neuroophthalmol. 2015 Sep;35(3):330-

81. Peter Wostyn, Veva De Groot, Debby Van Dam, Kurt Audenaert, H.E. Killer,Peter Paul De Deyn. A new glaucoma hypothesis: a role of CSF circulatory dysfunction: Fluids and Barriers in CSF 2015 Jun 29; 12(1):16

82. P. Wostyn, V. De Groot, D. Van Dam, K. Audenaert, H.E. Killer, P.P. De Deyn,Glaucoma and the role of cerebrospinal fluid dynamics.Invest Ophthalmol Vis Sci. 2015 Oct 1; 56(11):6630-1. doi: 10.1167/iovs.15- 18016.

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83. Pircher and H.E. Killer, TLP: a premature concept.Eye (Lond). 2015 Nov 13. doi: 1 0.1038/eye.2015.223. [Epub ahead of print]

84. Wostyn P, De Groot V, Van Dam D, Audenaert K, Killer HE, De Deyn PP circulation of cerebrospinal fluid: an alternative perspective on the protective role of high intracranial pressure in ocular hypertension. Clin Exp Optom. 2015 Dec 21. doi: 10.1111/cxo.12332. [Epub ahead of print]

85. C. Giger-Tobler, J. Eisenack, D. Holzmann, A. Pangalu, V. Sturm, H.E. Killer, K. Landau, G.P. Jaggi, Measurement of Optic Nerve Sheath Diameter: Differences between Methods?A pilot study. Klin. Monbl. Augenheilk. 2015 Apr; 232(4):467-47

86. Alzheimer's disease and glaucoma: can glymphatic system dysfunction underlie their comorbidity? Wostyn P, De Groot V, Van Dam D, Audenaert K, Killer HE, De Deyn PP. Acta Ophthalmol. 2016 Apr 29. doi: 87. Wostyn P, De Groot V, Van Dam D, Audenaert K, Killer HE, De Deyn Fast circulation of cerebrospinal fluid: an alternative perspective on the protective role of high intracranial pressure in ocular hypertension. PP.Clin Exp Optom. 2016 May;99(3):213-8.

88. Killer HE, Pircher A. What Do We Really Know About Translaminar Pressure? J Neuroophthalmol. 2016 Mar;36(1):112-3.

89. Wostyn P, De Groot V, Van Dam D, Audenaert K, Killer HE, De Deyn PP.Alzheimer's disease and glaucoma: can glymphatic system dysfunction underlie their comorbidity? Acta Ophthalmol. 2016 Apr 29 90. Wostyn P, De Groot V, Van Dam D, Audenaert K, Killer HE, De Deyn PP Age-related macular degeneration, glaucoma and Alzheimer's disease: amyloidogenic diseases with the same glymphatic background? Cell Mol Life Sci. 2016 Aug 29. 91. Wostyn P, De Groot V, Van Dam D, Audenaert K, Killer HE, De Deyn PP. Dilated Virchow-Robin spaces in primary open-angle glaucoma: a biomarker of glymphatic waste clearance dysfunction? Acta Radiol. Open. 2016 Aug 92. Translaminar pressure in Caucasian normal tension glaucoma patients. Pircher A, Remonda L, Weinreb RN, Killer HE. Acta Ophthalmol. 2016 Dec 14. doi: 10.1111/aos.13302. [Epub ahead of print] 93. Changes to the Aqueous Humor Proteome during Glaucoma. Kaeslin MA, Killer HE, Fuhrer CA, Zeleny N, Huber AR, Neutzner A. PLoS One. 2016 Oct 27;11(10):e0165314. doi: 10.1371/journal.pone.0165314.

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94. The two faces of the translaminar pressure difference: the biomechanical one and the biochemical one. Wostyn P, De Groot V, Van Dam D, Audenaert K, Killer HE, De Deyn PP.Clin Exp Optom. 2017 Jan;100(1):102-103. doi: 95. The Glymphatic System: A New Player in Ocular Diseases? Wostyn P, De Groot V, Van Dam D, Audenaert K, De Deyn PP, Killer HE.Invest Ophthalmol. Vis Sci. 2016 Oct 1;57(13):5426-5427. doi: 10.1167/iovs.16-20262. 96. Evidence for the existence of a communication between the eye and the brain? Wostyn P, De Groot V, Van Dam D, Audenaert K, Killer HE, De Deyn PP.Acta Neurochir (Wien). 2017 May 17 97. Relationship between the optic nerve sheath diameter and lumbar cerebrospinal fluid pressure in patients with normal tension glaucoma. Pircher A, Montali M, Berberat J, Remonda L, Killer HE. Eye (Lond). 2017 Apr 28. doi: 10.1038/eye.2017. 98. The Optic Canal: A Bottleneck for Cerebrospinal Fluid Dynamics in Normal-Tension Glaucoma? Pircher A, Montali M, Berberat J, Remonda L, Killer HE. Front Neurol. 2017 Feb 23;8:47. doi: 99. "Hypodense Holes" and the Ocular Glymphatic System: Author Response: "Black Holes" and the Ocular Glymphatic System. Wostyn P, De Groot V, Van Dam D, Audenaert K, De Deyn PP, Killer HE.Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1132-1133. 100. Glymphatic stasis at the site of the lamina cribrosa as a potential mechanism underlying open-angle glaucoma.Wostyn P, Killer HE, De Deyn PP. Clin Exp Ophthalmol. 2017 Jan 27. 101. Translaminar pressure in Caucasian normal tension glaucoma patients.Pircher A, Remonda L, Weinreb RN, Killer HE.Acta Ophthalmol. 2016 Dec 14. 102. Changes to the Aqueous Humor Proteome during Glaucoma. Kaeslin MA, Killer HE, Fuhrer CA, Zeleny N, Huber AR, Neutzner A. PLoS One. 2016 Oct 27;11(10 103. Why a One-Way Ticket to Mars May Result in a One-Way Directional Glymphatic Flow to the Eye. Wostyn P, Killer HE, De Deyn PP. J Neuroophthalmol. 2017 Oct 4. doi: 10.1097/WNO.0000000000000578. [Epub ahead of print] No abstract available.

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104. The Glymphatic Hypothesis of Glaucoma: A Unifying Concept Incorporating Vascular, Biomechanical, and Biochemical Aspects of the Disease. Wostyn P, De Groot V, Van Dam D, Audenaert K, Killer HE, De Deyn PP. Biomed Res Int. 2017;2017:5123148. doi: 10.1155/2017/5123148. Epub 2017 Aug 29. Review. PMID: 105. Reduced Free Communication of the Subarachnoid Space Within the Optic Canal in the Human. Killer HE, Pircher A. Am J Ophthalmol. 2017 Nov;183:164-165. doi: 10.1016/j.ajo.2017.09.011. Epub 2017 Sep 21. No abstract available. 106. Cell-Cell Interaction Proteins (Gap Junctions, Tight Junctions, and Desmosomes) and Water Transporter Aquaporin 4 in Meningothelial Cells of the Human Optic Nerve. Zeleny TNC, Kohler C, Neutzner A, Killer HE, Meyer P. Front Neurol. 2017 Jun 29;8:308. doi: 10.3389/fneur.2017.00308. eCollection 2017. PMID: 107. Evidence for the existence of a communication between the eye and the brain? Wostyn P, De Groot V, Van Dam D, Audenaert K, Killer HE, De Deyn PP. Acta Neurochir (Wien). 2017 Aug;159(8):1413-1414. doi: 10.1007/s00701-017-3218-9. Epub 2017 May 17. No abstract available. PMID: 108. Relationship between the optic nerve sheath diameter and lumbar cerebrospinal fluid pressure in patients with normal tension glaucoma. Pircher A, Montali M, Berberat J, Remonda L, Killer HE. Eye (Lond). 2017 Sep;31(9):1365-1372. doi: 10.1038/eye.2017.70. Epub 2017 Apr 28. PMID: 108. The Optic Canal: A Bottleneck for Cerebrospinal Fluid Dynamics in Normal-Tension Glaucoma? Pircher A, Montali M, Berberat J, Remonda L, Killer HE. Front Neurol. 2017 Feb 23;8:47. doi: 10.3389/fneur.2017.00047. eCollection 2017. PMID: 109. "Hypodense Holes" and the Ocular Glymphatic System: Author Response: "Black Holes" and the Ocular Glymphatic System. Wostyn P, De Groot V, Van Dam D, Audenaert K, De Deyn PP, Killer HE. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1132-1133. doi: 10.1167/iovs.16-21143. No abstract available. PMID:

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110. Glymphatic stasis at the site of the lamina cribrosa as a potential mechanism underlying open-angle glaucoma. Wostyn P, Killer HE, De Deyn PP Clin Exp Ophthalmol. 2017 Jul;45(5):539-547. doi: 10.1111/ceo.12915. Epub 2017 Feb 111. Modulation of the Emotional Response to Viewing Strabismic Children in Mothers- Measured by fMRI. Berberat J, Montali M, Gruber P, Pircher A, Hlavica M, Wang F, Killer HE, Remonda L. Clin Neuroradiol. 2017 Sep 14. doi: 10.1007/s00062-017-0625-5. [Epub ahead of print] 112. A. Pircher, M. Montali, P. Wostyn, J. Pircher, J. Berberat, L. Remonda and H.E Killer Impaired cerebrospinal fluid dynamics along the entire optic nerve in normal – tenison glaucoma. Acta Ophthalmol 2017 (in print) Book chapters

Orbital fractures: Diagnosis, operative treatment, secondary correctionsHogrefe & Huber 1995

Neuro-opthalomogogie Masson S.A.S. 2004 Chapters on: Axoplasmic flow, papilledema and drusen

Further publications

1. H.E. Killer und K. Hess. Langzeit-Katamnesen bei Röntgen- Plexusschädigung. Arch. Neurol. Psychiatr. 1990; 141: 22

2. H.E. Killer. Glaukom. Mikrozirkulation und Apoptose. Ophtha 1995; 3: 21

3. J. Issakainen, V. da Silva, H.E. Killer. Beidseitiges Papillenödem als isolierte Manifestation einer Borreliose. Monatszeitschr. Kinderheilk. 1997; 145: 1026

4. H.E. Killer, H.R. Laeng and P. Groscurth. Papilledema without intracranial pressure. Neuro-Ophthalmology 1997;18 (1):16 Suppl.

5. H.E. Killer Unilateral papilledema caused by a fronto-temporo- parietal arachnoid cyst. J Neuro-Ophthalmol. 2001; 156-158.

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6. H.E. Killer. When the world is turning upside down and the television keeps falling to the ground while dwarfs are parading on the ceiling. A complex case of visual hallucinations. J Neuro-ophthalmol 2001; 21 158.

7. H.E. Killer. Pseudotumor cerebri. Diagnose, Prognose und Therapie. Fokus 2002; 15.

8. H.E. Killer. Optic neuritis with extensive distension of the optic nerve sheath. J. Neuro- Ophthalmology 2002: 22: 172

9. H.E. Killer. Retinal vasospasm during an attack of migraine. J Neuroophthalmology. 2002;22: 172

10. H.E. Killer. The architecture of the arachnoid trabeculae and septae in the subarachnoid space of the human optic nerve: Anatomy and clinical considerations. Neuroophthalmology 2002; 22: 172

11. D. Eschle, G. Jaggi, H.E. Killer. Kopfschmerz und Erblindung Teil 1 Schweiz. Med. Forum 58-62 23.1.2008

12. D. Eschle, G. Jaggi, H.E. Killer. Kopfschmerz und Erblindung Teil 2 Schweiz. Med. Forum 75 – 79 30.1.2008

13. H.E. Killer, J. Flammer, G. Jaggi. Was ist die Ursache des Normaldruckglaukoms – und wo ist der Glaukomschaden. Ophtha 1: 9-10 2008

Abstracts / Posters

1. H.E. Killer, B. Blumer und R.M. Burde. Pseudotumor cerebri. Therapiemodalitäten und Verlaufsparameter. SOG, Lugano, 1991 Abstract und Vortrag.

2. H.E. Killer, B. Blumer and M. Mayers. Management of postoperative inflammation with topical cyclooxygenase inhibitors. 10th congress of the European soc of cat and refract surg. Abstract (1992). Paris.

3. H.E. Killer, B.Blumer and M. Mayers. Comparison of anti-inflammatory potency of two cyclooxygenase inhibitors. Internat symp of ocular inflamm. Jerusalem 1992. Abstract.

4. H.E. Killer and B. Blumer. The treatment of traumatic sixth nerve palsies with BotulinumA toxin. Europ. Strabologenkongress Salzburg 1993 Poster.

5. H.E. Killer, A. Forrer and A. Meyers .Bee sting into the cornea. Internat. Conf. of cornea and external disease. Jerusalem 1993. Abstract.

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6. H.E. Killer. Nonarteritic posterior ischemic optic neuropathy treated with optic nerve sheath decompression. North American Neuro-Ophthalmol Soc., USA 1994 Abstract und Poster.

7. H.E. Killer und A.M. Eggmann. AMPPE nach Bienenstich. Jahrestagung der schweiz. ophthalmologischen Gesellschaft, Aarau 1994. Poster.

8. H.E. Killer. Papilledema without elevated intracranial pressure. A new clinical syndrome? North American Neuro-Ophthalmol Soc. USA 1995. Poster und Abstract.

9. H.E. Killer, B. Blumer. Corneal penetration of diclofenac- gentamycin eye drops.Royal College of Ophthalmol 1995, Birmingham, England.Poster und Abstract.

10. H.E. Killer, A.M. Eggman, A. Forrer. Serous retinal detachment and bilateral swelling of the optic disc after a bee sting. North American Neuro-Ophthalmol Soc 1997 USA.Poster and Abstract.

11. J. Issakainen, V. da Silva, H.E. Killer. Beidseitiges Papillenödem - isolierte Manifestation einer Lyme Borreliose. Tagung Neuropädiatrie München 1997. Poster.

12. H.E. Killer, R.H. Laengand, P. Groscurth. Papilledema without increased intracranial pressure. EUNOS. London 1997. Abstract und Vortrag

13. H.E. Killer, R.H. Laeng and P. Groscurth. Abfluss von Liquor Cerebrospinalis in die Dura des Sehnervs. SOG Tagung Zürich 1998.Poster und Abstract.

14. H.E. Killer, R.H. Laeng and P. Groscurth. Cerebrospinal fluid drainage into the meninges of the optic nerve. North American Neuro- Ophthalmol Soc 1998 USA.(P oster und A bstract)

15. H.E. Killer, A. Huber, C. Portmann and J. Flammer. Bilateral nonarteritic anterior ischemic optic neuropathy and autoimmune thrombocytopenia.N orth A m erican N euro - Ophthalmol Soc. 1999 USA. (Poster und Abstract)

16. H.E. Killer. Diplopia, Ptosis and Hepatitis. EUNOS, Jerusalem September 1999. (Poster)

17. H.E. Killer. B. Wicki, Acute bilateral quadrantenaopsia after sequential bilateral retrobulbar neuritis in a patient with multiple sclerosis.N A N O S 2000, M ontreal (P oster und Abstract)

18. H.E. Killer, D. Holz, H.J. Kaiser and R.H .Laeng. Diplopia, Ptosis and hepatitis as presenting signs and symptoms of giant cell arteritis. NANOS 2000, Montreal(P oster und Abstract)

19. H.E. Killer and J. Flammer. Unilateral papilledema in a patient with a fronto- parientooccipitalarachnoidal cyst. NANOS. Palm Springs. Feb. 2001 (Poster and Abstract)

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20. H.E. Killer and U. Büttner. Multiple visual hallucinations in one individual patient. NANOS Palm Springs Feb. 2001. (Poster and Abstract)

21. H.E. Killer and J. Flammer. Retinal vasospasm during an attack of migraine. NANOS. Copper Colorad Feb. 2002. (Poster and Abstract)

22. H.E. Killer, A. Mironow and J. Flammer. Optic neuritis with extensive distension of the optic nerve sheath. NANOS Copper Colorado Feb. 2002. (Poster and Abstract)

23. H.E. Killer, H.R. Laeng, J. Flammer and P. Groscurth. The architecture of the arachnoid trabeculae and septae in the subarachnoid space of the human optic nerve.NANOS Copper Colorado Feb. 2002 (Poster and Abstract)

24. F.M. Sens., H.E. Killer, P. Meyer. Gradienten-Index (GRIN)- endoskopische Untersuchung des Subarachnoidalraumes des Nervus opticus. SOG 2002.(Poster und Abstrakt)

25. F.M. Sens, H.E. Killer, P. Meyer. Erste Grandienten-Index (GRIN)- endoskopische Aufnahmen aus dem Subarachnoidalraum des Nervus opticus. DOG 2002.

26. H.E. Killer, A.A. Mironow, J. Flammer, Neuritis nervi optici mit massiver Ausweitung des Subarachnoidalraums des N. opticus. SOG, Luzern, Oktober 2002.

27. H.E. Killer. H.R. Laeng, J. Flammer, P. Groscurth. Architektur der arachnoidalen Trabekel und Septen im Subarachnoidalraum des menschlichen Sehnervs: Anatomie und klinische Überlegungen. SOG, Luzern, Oktober 2002.

28. P. Schöneborn, J. Flammer, H.E. Killer. Retinal one and a half syndrome.SOG, Luzern, Oktober 2002.

29. H.E. Killer, H. Kordic. Posterior ischemic optic neuropathy after lower eyelid blepharoplasty. North American Neuroophthalmological society Snowbird USA 10.2 2003 (Poster and abstract)

30. H.E. Killer, A. Balwani. Vaccination for vacation followed by optic disc swelling.N A N O S Orlando, USA, April 2004. (Poster and abstract)

31. Hatz, Brodsky, H.E. Killer. Surgical treatment of superior oblique palsy.NANOS Orlando, USA, April 2004. (Poster and abstract)

32. M. Casotti , H.E. Killer. Primary large B-cell lymphoma of the central nervous system presenting with vitreous infiltration, auditory hallucinations and psychotic epsiodes.N A N O S C olorado Februar 2005 (P oster and abstract)

33. M. Casott, H.E. Killer. Primary large B-cell lymphoma of the central nervous system presenting with vitreous infiltration, auditory hallucinations and psychotic epsiodes.EUNOS Moskau Juni 2005 (Poster and abstract)

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34. G. Jaggi, H.E. Killer. Unilateral swollen optic disc with inhomogeneous cerebro-spinal fluid composition in the spinal canal and the subarachnoid space of the optic nerve.EUNOS Moskau 2005.

35. P. Knecht, P. Groscurth, H.E. Killer. Is silicone oil optic neuropathy depending on intraocular pressure alone? EUNOS Moskau 2005

36. G. Jaggi, R.L. Laeng, M. Müntener and H.E. Killer. The anatomy of the muscle insertion (scleromuscular junction) of the lateral and medial rectus muscle in humans. EUNOS Moskau 2005.

37. H.E. Killer, G. Jaggi, J. Flammer, N.R. Miller, A. Huber. Cerebrospinal fluid composition. A clue to optic nerve compartment syndroms. NANOS 2006 February Tucson USA

38. G. Jaggi, H.E. Killer. Unilateral optic disc swelling. NANOS 2006 February Tucson USA. (Poster and abstract)

39. H.E. Killer et al. Visual loss in idiopathic intracranial hypertension despite normal intracranial pressure. 1st world congress on controversies in Neurology, Berlin Sept. 2007

40. G.P. Jaggi, A. Huber, J. Flammer and H.E. Killer. Lipocalin-like Prostaglandin D Synthase in subretinal fluid of detached retinas in humans. SOG Montreux Sept. 2007

41. G.P. Jaggi, J. Flammer, Andreas R. Huber and H.E. Killer. Lipocalin- like Prostaglandin D Synthase in subretinal fluid of detached retinas in humans. NANOS Orlando März 2008

42. H.E. Killer, G.P. Jaggi, J. Flammer, N.R. Miller, A.R. Huber, A. Mironov. Cerebrospinal fluid dynamics between the intracranial and subarachnoid space of this optic nerve. Is it always bidirectional? NANOS Orlando März 2008

43. XiaorongXin, H.E. Killer, Josef Flammer, Peter Meyer. Primary cell culture of meningeothelial cells a new model for future studies of optic nerve disease.ARVO 2008 Florida

44. H.E. Killer. Papilledema and normal tension glaucoma. Two sides of the same coin? AGS meeting Naples 2010

45. G. Jaggi, J. Flammer, L. Remonda, H.E. Killer. Vergrösserter Optikusscheidendurchmesser in Patienten mit Normaldruckglaukom. SOG 2011 Interlaken

45. H.E. Killer, N.R. Miller, R. Weinreb, G. Jaggi, L. Remonda. Cerebrospinal fluid pressure in patients with normal tension glaucoma. Where and how to measure the pressure? AGS New York March 2012

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46. A. Pass, H. Hansen, H.E. Killer, A. Nuney, E. Bershad, T. Mader. R. Gibson. Long- durations exposure to zero gravity. Disc edema, optic nerve sheath distension and increaded intracranial pressure. Hydrocephalus, 2012 Juni, Athen

47. Christian Giger-Tobler, Johannes Eisenack, David Holzmann, Athina Pangalu, Veit Sturm, Hanspeter Esriel Killer, Klara Landau, Gregor Peter Jaggi, Measurement of optic nerve sheath diameter by CT, MRI and ultrasound. SOG 2014 Interlaken

48. Garas A, Dishy A, Killer H.E. Acute solar retinopathy by nocturnal lagophthalmos SOG Fribourg August 2015 49. Achmed Pircher*,1 Margherita Montali*,1,2 Jatta Berberat,2 Ph.D., Luca Remonda,2 MD, and Hanspeter Esriel Killer, 1 MD The Optic Canal: A Bottle Neck for Cerebrospinal Fluid Dynamics in Normal Tension Glaucoma ARVO Baltimore 2017 50. Thi Ngoc Co Zeleny 2*, Corina Kohler 1*, Albert Neutzner 1, Hanspeter E. Killer 1,2, Peter Meyer 1 Cell-Cell Interaction Proteins and Aquaporin 4 in Meningothelial Cells of the Human Optic Nerve ARVO Baltimore 2017 Invited lectures

1. H.E. Killer. Neuroophthalmologisches Kolloquium (Optikusneuritis) Augenklinik Universitätsspital Zürich 1992.

2. H.E. Killer. Dystonien im Gesichtsbereich. Blepharospasmus, Hemispasmusfacialis und Lidöffnungsapraxie. Schweizerische Gesellschaft für Muskelerkrankungen. Zürich,N ovem ber 1992.

3. H.E. Killer. Optic nerve sheathdecompression. Ben Gurion Universität, Beer Sheva, Israel 1993.

4. H.E. Killer. Vom Rezeptor zum Sehen. Vortrag an der Rehabilitationsklinik Zurzach August 1993.

5. H.E. Killer. Autoimmun-Optikus-Neuropathien. Zürcher Fortbildungskurs der Universität, Augenklinik, Zürich. 22. Oktober 1993.

6. H.E. Killer. Abklärung komplexer Hirnnervenparesen. Makkabi Medical Center Tel Aviv, Israel, 1994.

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7. H.E. Killer. PION, Papillenödem ohne Hirndruck. Hypothesen und Tatsachen ONO - Kolloquium Universität Zürich, Oktober 1995.

8. H.E. Killer. Botulinumtoxin: Altes und Neues. Schweizerische Dystoniegesellschaft, Paulusakademie Zürich, März 1996.

9. H.E. Killer. Möglichkeiten des operativen Zugangs bei Schieloperationen: Gross- und Kleinschnittchirurgie. Jahrestag der operierenden Augenärzte Deutschlands, NürnbergJuni 1996. K iller. B asiskurs S chielchirurgie. Jahrestag der operierenden

10. H.E.Augenärzte Deutschlands, Nürnberg 1996. Killer. Grand rounds. Albert Einstein College of Medicine, New Killer. Diagnostik und Therapie bei Retrobulbärneuritis. SOG Killer. Optikusscheidendekompression. Indikation, Technik. Kongress der Deutschen Ophthalmochirurgen. 1997 Nürnberg.

14. H.E. Killer. Diagnostik und Therapie bei Augenmuskelparesen. 10. Kongress der Deutschen Ophthalmochirurgen 1997 Nürnberg.

15. H.E. Killer. Differentialdiagnose der Retrobulbärneuritis. Einladung der Rheumaklinik Schinznach Bad 1998.

16. H.E. Killer. Stauungspapille ohne Hirndruck. Zürcher Fortbildungstag Neuroophthalmologie Zürich,1998.

17. H.E. Killer. Was lehrt uns die Papille? Jahrestagung der schweizerischen Augenärztegesellschaft, 1998 Zürich.

18. H.E. Killer. Papillenödem: Von der Morphologie zur Diagnose. Ophthalmologie-Tagung Kantonsspital Luzern 1998.

19. H.E. Killer. Ptose, Diplopie und Hepatitis. Strabologische und Neuroophthalmologische Falldemonstrationen, St. Gallen März 1999.

20. H.E. Killer. The meninges of the optic nerve - new insights. Invited lecture:Albert Einstein College of Medicine, New York, März 1999

21. H.E. Killer. Management of Pseudotumor cerebri with and without papilledema. EUNOS, Jerusalem September 1999. (Chairperson für die Session: The optic nerve).

22. H.E. Killer. Ultrastructural anatomy of the meninges of the human optic nerve. New insights. EUNOS, Jerusalem September 1999. (Chairperson für die Session über Erkrankungen des Sehnervs).

23. H.E. Killer. Wenn die Welt auf dem Kopf steht. Ophthalmologische Knacknüsse 2, Kantonsspital Luzern (25.2.2000).

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24. H.E. Killer. Frontalissuspensation bei schweren Fällen von Blepharospasmus. Jahrestagung der schweizerischen Dystoniegesellschaft. Paulusakademie Zürich. 12.3.2000. 25. H.E. Killer. Pseudotumor cerebri. SOG, Bern, 15.9.2000. 26. H.E. Killer. Klinisch wichtige Aspekte der Pupillenbahn. Ophthalmo-Meeting Basel, 20./21. Oktober 2000 27. H.E. Killer. Funktioneller Visusverlust. Strabismusseminar der SOG. Luzern, März 2001 28. H.E. Killer. Einseitiges Papillenödem. Klinik und Pathophysiologie. St. Galler Ophthalmologie-Tagung. St. Gallen. Mai. 2001

29. H.E. Killer. Optic nerve sheathfenestration. Universität Lausanne. 11.10. 2001

30. H.E. Killer. Papillenödem und Glaukom. Neue Aspekte. Neurologiefortbildung KSA. 8.11. 2001.

31. H.E. Killer, S. Frischknecht. Strabismussymposium der SOG. Luzern 12.4.2002

32. H.E. Killer. Abklärung der geschwollenen Papille im Kindesalter. Schweizerische Gesellschaft für Neuropädiatrie KSA 24.4.2002

33. H.E. Killer, J. Flammer. Einseitiges Papillenödem. Papillitis oder Stauungspapille oder beides zusammen. Strabologische und Neuroophthalmologische Falldemo St. Gallen 7.6.2002

34. H.E. Killer. Lidchirurgie. Vorlesung im Rahmen der Chirurgischen Fortbildung an der Universität Basel. 25.6.2002.

35. H.E. Killer. Entwicklung der kindlichen Sehkraft. Kantonale Gesellschaft für Schulkinderuntersuchungen. KSA 7.11.2002

36. H.E. Killer. The prominent optic disc. 1.1.2002 Rabbin Medical Center Tel Aviv, Israel

37. H.E. Killer. Unilateral papilledema and the missing tendon in extraocular muscles. 7.2.2003 Albert Einstein College of Medicine, New York

38. H.E. Killer. The anatomy of the muscle insertion of the medial and lateral extraocular muscles. North American Neuroophthalmological Society Snowbird USA, 10.2 2003

39. H.E. Killer. Vaskuläre Affektionen des Sehnervs und der Retina. Fortbildung für die Aargauischen Neurologen. 19.5.2003

40. H.E. Killer. Kortikale Bildgenese und Bildsteuerung.Jahrestagung der Schulpsychologen des Kantons St. Gallen. Rorschach. März 2004

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41. H.E. Killer. Die Prominente Papille. DD und Therapie. Ophthalmologische Fortbildungskurse Von Hoff. April und Mai 2004, Zürich.

42. H.E. Killer. Wie und wo entstehen Bilder über die Welt in unserem Kopf? Publikumsvortrag am KSA Mai 2004

43. H.E. Killer. Visuelle Wahrnehmungsstörungen aus interdisziplinärer Sicht. Olten, Juni 2004

44. H.E. Killer. Anatomical considerations on papilledema. INOS 2004, July, Geneva

45. H.E. Killer. Entzündungen am Sehnerv. Basler Fortbildungstage Oktober 2004

46. H.E. Killer. P. Knecht, R.M. Laeng, P. Grosscurth. Is silicone oil optic neuropathy depending on intraocular pressure alone? An experimental study.NANOS (Colorado USA) Februar 2005

47. H.E. Killer. The anatomy of the SAS and its clinical implication on unilateral papilledema and cerebrospinal fluid composition and dynamics. A clinical and anatomical and biochemical study. EUNOS Moskau, Juni 2005

48. H.E. Killer. Der Sehnerv. Ein neues Fenster in den Liquor cerebrospinalis? Fortbildung Neurologie, Neurochirurgie und Ophthalmologie KSA 8.9.2005 49. H.E. Killer. The optic nerve. A separate CSF compartment? Hadassa Universitiy hospital, Jerusalem, Israel November 2005 50. H.E. Killer. Erkrankungen des Sehnervs. Basler Fortbildungstage Oktober 2005 51. H.E. Killer. Botulinumtoxin bei neuroophthalmologischen Indikationen. Interdisziplinäre Fortbildung Neurologie KSA, Juni 2006 52. H.E. Killer. Plenarsitzung (Panelmitglied) über Neuroophthalmologie an der SOG in Lugano, September 2006 53. H.E. Killer. Does the optic nerve live in a biotop? Basler Glaukomtage Oktober 2006

54. H.E. Killer. Diplopie, Zeichen einer neuroophthalmologischen Erkrankung. Strabismuskolloquium SOG Luzern. Mai 2006

55. H.E. Killer. Paneldiskussion über Neuroophthalmologie. SOG Luzern, Oktober 2006

56. H.E. Killer. Does the optic nerve live in a separate CSF compartment? Hadassa University hospital, Jerusalem, Israel. October 2006

57. H.E. Killer. Papilledema. 4.1.2007. Zentrum für Lehre und Forschung Basel.Einladung durch Prof. Steck. Neurologie Uni Basel.

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58. H.E. Killer. Ocular motility. Optic nerve. Swiss eye weekly, basic science cours.B runnen. 16.1.2007

59. H.E. Killer. Is normal tension glaucoma related to senescence of cerebrospinal fluid?

AGS (American glaucoma society) San Francisco März 2007

60. H.E. Killer et al. Visual loss in idiopathic intracranial hypertension despite normal

intracranial pressure. 1st world congress on controversies in Neurology, Berlin Sep

2007

61. H.E. Killer. Hirndruckpapille ohne Hirndruck. Universität Zürich. Fortbildung für Augenärzte. 15.10.2007

62. H.E. Killer. Ophthalmologische Notfälle. Interessegruppe Notfallpflege schweiz. Zentrum für Lehre und Forschung, Uni Basel. 24.10.2007

63. H.E. Killer. Basic science course optic nerve, strabismus. Brunnen, Feb. 2008

64. H.E. Killer. Is normal tension glaucoma related to reduced CSF circulation around the optic nerve. NANO 2008 Orlando

65. H.E. Killer. CSF in subarachnoid space and basal cisterns. INOS Napa valley, June 2008 Special lecture

66. H.E. Killer. Inkomitante Schielformen bei Hirnstammläsionen. SOG Sept 2008 Interlaken

67. H.E. Killer. Pathologie und Anatomie beim Pseudotumor cerebri. DOG Sept 2008 Berlin

68. H.E. Killer. Ocular motility and optic nerve and chiasm. Basic science course.Biel, February 2009

69. H.E. Killer. Is normal tension glaucoma caused by optic nerve compartments? New York Eye Infirmery, New York, May 2009

70. H.E. Killer. Ist die Pathophysiologie der Stauungspapille wirklich verstanden? Universitätsaugenklinik Tübingen. Tübinger Augenärzteabend. Juli 2009

71. H.E. Killer. Is strabismus surgery cosmetic surgery? Basler Augentage. Oktober 2009

72. H.E. Killer. “Papilledema: Is the pathophysiology really understood?" Wilmer Eye Institute, Johns Hopkins Hospital, August 2009

73. H.E. Killer. Papilledema and normal tension glaucoma. Two sides of the same coin? New York University, March 2010

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74. H.E. Killer. Cerebrospinal fluid circulation in normal tension glaucoma. Mayo Clinic Ophthalmology department, Rochester, USA. Oktober 2010

75. H.E. Killer. Cerebrospinal fluid circulation in Papilledema. Mayo Clinics, dep. of Neurology, Rochester USA

76. H.E. Killer. Optic nerve, ocular motility. Swiss Eye Week, Biel. Januar 2011

77. H.E. Killer. Symposium: The optic nerve. UKNOSIG Birmingham, March 2011

78. H.E. Killer. SOE and AAO Geneva, Juni 2011

78. H.E. Killer. Optikus-Kompartementsyndrom. Augenärzte Fortbildung Uni Basel,August 2011

79. H.E. Killer. Painful oculomotor palsy. SOG Interlaken, August 2011

80. H.E. Killer. Optic nerve compartment syndroms. Glaucoma think tank, New York, September 2011

81. H.E. Killer. CSF Production and dynamics Glaucoma think tank, New York,September 2011

82- H.E. Killer. Entwicklung des Binokularsehens, Amblyopie. Universität Bern,Oktober 2011

82. H.E. Killer. The microenvironment of the optic nerve. New York University, March 2012

83. H.E. Killer. Nystagmus, Paresen und was wir sonst noch so lieben. Augenzentrum Basel Bahnhof, Januar 2012

84. H.E. Killer. Interdisziplinäre Fortbildung für Ophthalmologen, Gastroenterologen und Rheumatologen. Lenzburg, Juni 2012

85. HE Killer. Le nerf optique. Journee des Ophthalmologes Romands. Grandson. 1.11.2012

86. H.E. Killer. Optic nerve sheath compartment and normal tension glaucoma.A sian Pacific congress Hyderabad,India, January 2013

87. H.E. Killer. Optic nerve compartmentation in normal tension glaucoma. International Symposium on ocular pharmacology and therapeutics 2013, Paris (ISOPT 2013)

88. Strabismus und Amblyopie. Pädiatriekongress Aarau, März 2013

89. Sehnervenerkrankungen auf Erden wie im Himmel. Fortbildung Neurologie April 2013

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90. H.E. Killer. Is it glaucoma? Managing glaucoma: Beyond intraocular pressure.San Francisco. April 2013

91. H.E. Killer. Relationship of ICP (and CSF pressure) to glaucoma damage: Managing glaucoma: Beyond intraocular pressure. San Francisco, April 2013

92. H.E. Killer Wer leidet durch den Strabismus? 19. Strabologische und neuroophthalmologische Falldemonstrationen, St. Gallen, Juni 2013

93. H.E. Killer. Optic nerve compartment syndrome. NASA VIIP RCAP, November 2013, Houston Texas

94. H.E. Killer. Normal tension glaucoma and cerebrospinal fluid. ANZGIG Perth Feb. 2014

95. H.E. Killer. Der Grüne Star und der rote Planet. Was haben sie gemeinsam? Strabologische und neuroophthalmologische Falldemonstrationen, St. Gallen, Juni 2014

96. H.E. Killer. Glaukom und Normaldruckglaukom eine Pathologie hinter dem Auge? Inselspital Bern, November 2014

97. H.E. Killer. Visuelle Halluzinationen. Weihnachtslektüre für die Neurologen des Kantons Aargau, November 2014

98. H.E. Killer. Der Strabismus im Gehirn des Betrachters. Vorlesung Uni Mainz.Dezember 2014

99. H.E. Killer. Zermatt meeting glaucoma. January 2015

100. H.E. Killer. Visual impairment and intracranial pressure (VIIP) an emerging health issue in space. International astronautical congress. October 2015, Jerusalem

101. H.E. Killer. Is translaminar pressure relevant in glaucoma? Belgian glaucoma society Brüssel November 2015

102. H.E. Killer. Was ist das Glaukom – nicht. Basler Glaukomtage Basel 2015

103. Glymphatics in the optic nerve. Glaucoma think tank New York June 2016

104. Zwei Augen, ein Gehirn, drei Dimensionen. Jahrestagung der schweizerischen Neuropsychologen Zürich Mai 2016

105. Translaminar pressure. Holy grail or empty chalice. EGS Prag Juni 2016

106. Cerebrospinal fluid circulation and its relationship to glaucoma. Intraocular and intracranial pressure related disease. International summit Peking, China. August 2016

107. H.E. Killer. Die Bedeutung des Hirndrucks für das Glaukom. Glaukom workshop Berlin Januar 2017

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108. HE Killer. Glaucoma and Alzheimers’disease . AISG Rom Mai 201

109. HE Killer. The two faces of the translaminar pressure. The biomechanical and the biochemical one. World congress Glaucoma Helsinki 110. HE Killer. Visuelle Halluzinationen. Was passiert im Kopf des Betrachters? Schweizerische Gesellschaft für allgemeine innere Medizin. Bern 14.9.2017 111. Glaucoma, Alzheimers and the meningothelial cell. Tongren Eye institue of Peking University October 2017 112. H.E Killer. Cerebrospinal fluid pathway and the optic nerve Key note lecture: Belgian congress of ophthalmology, Brussels November 2017