CURRICULUM VITAE - api.cedars-sinai.org
Transcript of CURRICULUM VITAE - api.cedars-sinai.org
Mark Vrahas, MD
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CURRICULUM VITAE
Name: Mark Steven Vrahas, M.D.
Personal History: Cedars-Sinai Medical Center
Department of Orthopaedic Surgery
8700 Beverly Blvd, North Tower, Suite 8215
Los Angeles, Ca 90048
Phone: 310-423-3702
DOB: 4/19/1958
Birthplace: Dubois, Pennsylvania
United States
Married
Education: 1980 BS, Chemistry, Allegheny College, PA
cum laude Honors Graduate in Chemistry
1984 MD,Medicine, University of Pittsburgh, PA
2017 Masters of Health Care Delivery Science, Dartmouth University
(Current student – to graduate 1/2017)
Postdoctoral Training
1984 – 1985 Internship-General Surgery University of Pittsburgh
1985 - 1986 Research, Fellow Biomechanics University of Iowa
1986 - 1989 Resident, Orthopaedics University of Pittsburgh
1989 - 1990 Müller Fellow, Orthopaedic University of Toronto
Traumatology Pelvic Sunnybrook Hospital
and Acetabular Surgery
(Marvin Tile, M.D.)
07/02/90 – Traveling AO Fellowship Hip Surgery Bern, Switzerland
08/03/90 (Professor Ganz)
08/06/90 – Traveling AO Fellowship Traumatology Hanover, Germany
09/21/90 (Professor Tscherne)
09/22/90 – Traveling AO Fellowship Acetabular Surgery Paris, France
10/20/90 (Emile Letournel, M.D.)
Licensure: MA license 160413 & NH License 13363
Board Certification: Orthopaedic Surgery
Mark Vrahas, MD
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Professional Current
Experience:
2016- Active Staff Cedars-Sinai Medical Center
1999 - Active Staff Brigham & Women’s Hospital
1999 - Active Staff Massachusetts General Hospital
1999 - Active Staff Spaulding Rehabilitation Hospital
2006 - Active Staff, Admitting Privileges Speare Memorial Hospital
Past
1990 - 1993 Active Staff Milton S. Hershey Medical Center
1993 – 1999 Active Staff Kenner Regional Medical Center
1993 - 1999 Active Staff University Hospital - New Orleans
2001 - 2004 Consultant Medical Staff Shriners Burns Hospital – Boston
2004 - 2006 Active Staff Beth Israel Deaconess Medical Center
2010 Active Staff, Temporary Beth Israel Deaconess Medical Center
Faculty Academic Appointments
1989 – 1990 Instructor Orthopaedic Surgery University of
Toronto
1990 – 1993 Assistant Professor Orthopaedic Surgery Pennsylvania
State University
1993 - 1997 Assistant Professor Orthopaedic Surgery Louisiana State
University
1997 – 1999 Associate Professor Orthopaedic Surgery Louisiana State
University
1999 - 2007 Assistant Professor Orthopaedic Surgery Harvard
Medical School
2007 - 2015 Associate Professor Orthopaedic Surgery Harvard
Medical School
2014 - Present Professor Orthopaedic Surgery Harvard
Medical School
Major Administrative Leadership Positions (Professional History)
Local
1991 Course Organizer, Trauma-Rama
PA State University, Operating Room Dept.
1995 Program Chairman, Louisiana Orthopaedic Association
Charity Hospital–New Orleans 42nd Annual Meeting-Trauma at
the New Charity
1993 – 1995 Co-Director, LSU Trauma Management Workshop
Louisiana State University
1993 - 1999 Director, Orthopaedic Trauma
New Orleans Charity Hospital
1997 - 1999 Director, Orthopaedic Trauma
LSU Health Care System
1999 - 2001 Chief, Orthopaedic Trauma Service
Massachusetts General Hospital
Mark Vrahas, MD
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1999 - 2000 Chief, Orthopaedic Trauma Service
Brigham and Women’s Hospital
1999 - Chief, Partners Orthopaedic Trauma Service
Brigham and Women’s Hospital
1999 - Chief, Partners Orthopaedic Trauma Service
Massachusetts General Hospital
2000 - 2015 Director, Partners Orthopaedic Trauma Fellowship
Massachusetts General Hospital/Brigham and Women’s Hospital
2000 - 2014 Course Director, New England Trauma Summit
Harvard Medical School
2011 - Co-Director, Geriatric Inpatient Fracture Service (aka GIFTS)
Massachusetts General Hospital
2011 - Surgeon Director, Lunder 3 Orthopaedic Operating Rooms
Massachusetts General Hospital
2011 - Administrative Lead, Orthopaedic Innovation Team
Massachusetts General Hospital
2014 - Vice Chairman, Department of Orthopaedic Surgery
Massachusetts General Hospital
2014 - Chairman - Harvard Medical School Orthopedic
Harvard Medical School Trauma Initiative
2015- Partners Health Care, Orthopaedic Representative to
Partners Health Care Population Health
National
1994 Co-Chairman, AO/ASIF Operating Room Personnel Course
AO/ASIF
1995 Co-Chairman, AO/ASIF Continuing Education Program
AO/ASIF
2000 Co-Chairman, First Annual Chicago Trauma Symposium
Advocate Healthcare
2001 - Co-Chairman, AO New England Regional Fracture Summit
AO/ASIF
2003 Co-Chairman, Fractures of the Pelvis and Acetabulum:
State of the Art Management Techniques
AAOS
2006 Organizer/Moderator, AAOS Instructional Course
AAOS
2007 Co-Chairman, ABJS Symposium
ABJS
2008 Co-Chairman, Sunnybrook Meeting -
“Hip Disorders, Child to Adult: A Transatlantic Forum”
London Finsbury Orthopaedics
2013 Co-Chairman, AO New England Regional Fracture
Summit AO/ASIF
International
Mark Vrahas, MD
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1998 Course Organizer, AAOS Trauma and Sports Medicine Course
for the Dominican Republic – Santo Domingo, Dominican
Republic
AAOS
2005 Co-Chairman, AO/ASIF Basic and Advanced Fracture
Management Course – Marco Island, FL
AO Foundation
2007 Co-Chairman/Organizer, Carl T. Brighton Workshop on
Musculoskeletal Trauma in Low and Middle Income Countries -
India
ABJS
Research Investigations
12. Vrahas, M.S., Wilson, S.C., Cummings, P.D. & Paul, E.M. 1998, "Comparison
of Fixation Methods for Preventing Pelvic Ring Expansion", Orthopedics, vol. 21, no.
3, pp. 285-289.
14. Vrahas, M.S., Widding, K.K. & Thomas, K.A. 1999, "The Effects of Simulated
Transverse, Anterior Column, and Posterior Column Fractures of the Acetabulum on
the Stability of the Hip Joint", The Journal of Bone and Joint Surgery, American
Volume, vol. 81, no. 7, pp. 966-974.
20. Bhattacharyya, T. & Vrahas, M.S. 2004, "The Medical-Legal Aspects of
Compartment Syndrome", The Journal of Bone and Joint Surgery, American Volume,
vol. 86-A, no. 4, pp. 864-868.
22. Murray, M.M., Zurakowski, D. & Vrahas, M.S. 2004, "The Death of Articular
Chondrocytes after Intra-articular Fracture in Humans", The Journal of Trauma, vol.
56, no. 1, pp. 128-131.
25. Bhattacharyya, T., Crichlow, R., Gobezie, R., Kim, E. & Vrahas, M.S. 2006,
"Complications Associated with the Posterolateral Approach for Pilon Fractures",
Journal of Orthopaedic Trauma, vol. 20, no. 2, pp. 104-107.
26. Bhattacharyya, T., Vrahas, M.S., Morrison, S.M., Kim, E., Wiklund, R.A.,
Smith, R.M. & Rubash, H.E. 2006, "The Value of the Dedicated Orthopaedic Trauma
Operating Room", The Journal of Trauma, vol. 60, no. 6, pp. 1336-40; discussion
1340-1.
28. Crichlow, R.J., Andres, P.L., Morrison, S.M., Haley, S.M. & Vrahas, M.S. 2006,
"Depression in Orthopaedic Trauma Patients, Prevalence and Severity", The Journal
of Bone and Joint Surgery, American Volume, vol. 88, no. 9, pp. 1927-1933.
30. O'Toole, R.V., Gobezie, R., Hwang, R., Chandler, A.R., Smith, R.M., Estok,
D.M.,2nd & Vrahas, M.S. 2006, "Low Complication Rate of LISS for Femur
Fractures Adjacent to Stable Hip or Knee Arthroplasty", Clinical Orthopaedics and
Related Research, vol. 450, pp. 203-210.
33. Rightmire, E., Zurakowski, D. & Vrahas, M. 2008, "Acute Infections After
Fracture Repair: Management with Hardware in Place", Clinical Orthopaedics and
Related Research, vol. 466, no. 2, pp. 466-472.
Mark Vrahas, MD
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42. Weaver, M.J., Harris, M.B., Strom, A.C., Smith, R.M., Lhowe, D., Zurakowski,
D. & Vrahas, M.S. 2011, "Fracture Pattern and Fixation Type Related to Loss of
Reduction in Bicondylar Tibial Plateau Fractures", Injury.
46. Weaver, M.J., Bruinsma, W., Toney, E., Dafford, E., & Vrahas, M.S. 2012,
“What Are the Patterns of Injury and Displacement Seen in Lateral Compression
Pelvic Fractures”, Clinical Orthopaedics and Related Research, vol. 470, no. 5,
[online]
47. Miller, M.A., Liu, W., Zurakowski, D., Smith, R.M., Harris, M.B., & Vrahas,
M.S. 2012, "Factors Predicting Failure of Patella Fixation.", The Journal of Trauma
and Acute Care Surgery, vol. 72, no. 4, pp. 1051-1055.
55. Bachoura A, Guitton TG, Smith RM, Vrahas MS, Zurakowski D, Ring D.
Infirmity and injury complexity are risk factors for surgical-site infection after
operative fracture care. Clin Orthop. 2011;9:2621-2630.
56. Dai T, Garcia B, Murray CK, Vrahas MS, Hamblin MR. UVC light prophylaxis
for cutaneous wound infections in mice. Antimicrob Agents Chemother.
2012;7:3841-3848
58. Weaver MJ, Harris MB, Strom AC, Smith RM, Lhowe D, Zurakowski D, Vrahas
MS. Fracture pattern and fixation type related to loss of reduction in bicondylar tibial
plateau fractures. Injury. 2012;6:864-869.
59. Miller MA, Liu W, Zurakowski D, Smith RM, Harris MB, Vrahas MS. Factors
predicting failure of patella fixation. J Trauma Acute Care Surg. 2012;4:1051-1055.
68. Liu W, Zhou D, Liu F, Weaver MJ, Vrahas MS. Mechanical complications of
intertrochanteric hip fractures treated with trochanteric femoral nails. J Trauma Acute
Care Surg. 2013;2:304-310.
75. Vranceanu AM, Bachoura A, Weening A, Vrahas M, Smith RM, Ring D.
Psychological factors predict disability and pain intensity after skeletal trauma. J
Bone Joint Surg Am. 2014;3 e20.
Professional Societies
Activities:
1987 - Orthopaedic Research Society
1997 - 1998 Local Host - Annual Meeting
1998 - 1999 Member, Program Committee
1992 - American Board of Orthopaedic Surgery
1992 - American Academy of Orthopaedic Surgeons
1995 – 1998 Co-Director, International Committee
1997 Moderator
1998 - 1999 Member, International Committee
1999 - 2000 Member, Program Committee
2002 Moderator
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2005 DVD Producer
1992 - AO Alumni Association
1992 - 1993 Pennsylvania Orthopaedic Society
1993 - 1999 Orleans Parish Medical Society
1994 - 1999 Member, EMS Sub-Committee
1993 - 1999 Louisiana Orthopaedic Association
1995 - 1996 Program Chairman
1993 - 1999 Greater New Orleans Orthopaedic Society
1993 - Orthopaedic Trauma Association
1997 - 2003 Member, Research Committee
1998 - 1999 Member, Nominations Committee
1999 - 2000 Member, Massachusetts Casualty Committee
2006 - 2007 Member, Fund Development Committee
1993 - Eastern Association for the Surgery of Trauma
1993 – 2009 Eastern Orthopaedic Association
1994 - American College of Surgeons
1998 - 1999 State Chairman, Committee on Trauma
2000 - 2005 Consultant, Committee on Verification
2000 - 2005 Consultant, Committee on Trauma Systems
2000 - Ad hoc Program Reviewer 1995 - 2009 Academic Orthopaedic Society
1995 - 1997 Societe Internationale Chirurgie Orthopedique et de
Traumatologie (SICOT)
1996 – 1999 American Society of Biomechanics
1997 - 1998 Annual Meeting, Local Host
1998 - 1999 Program Committee, Member
1998 - 2003 Clinical Orthopaedic Society
1999 - AO Foundation
1999 - Trustee
2003 - 2008 Member, Board of Trustees
2005 - 2007 Member, LEEG - Lower Extremity Expert Group
2005 - 2007 Member, Trauma SAcC – Specialty Academic Committee
2005 - 2008 Co-Director, Bone Defect Clinical Priority Program
2006 Moderator, AO/ASIF Nursing Continuing Education
2007 - Member, Clinical Investigation and Documentation Board (CID)
2007 - Member, Trauma Research Committee (TRC)
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2008 - 2010 Member, Exploratory Research Board (ERB)
2011 - Ex-Officio Member, Board of Trustees
2011 - 2015 Chairman, Clinical Investigation and Documentation Board
(CID)
2011 - 2014 Member, Academic Council (AcC)
2011 - 2015 Executive Board Member, Technical Commission (AOTK)
2001 - Massachusetts Orthopaedic Association
2001 - 2004 Member, Board of Directors
2000 – 2003 Twentieth Century Orthopaedic Association
2003 –2012 American Orthopaedic Association
2006 - Association of Bone and Joint Surgeons
2012 - Asociacion Argentina de Ortopedia y Traumatologia
Editorial Activities
Ad hoc Reviewer
1992 - 2006 Journal of Biomechanics
1995 - Journal of Trauma
1997 - Journal of the AAOS
2005 - Journal of Bone and Joint Surgery
2005 - Journal of Orthopaedic Trauma (JOT)
2005- Injury
2009- Journal of Bone and Joint Surgery, British Edition
Other Editorial Roles
1993 – 1999 Editorial Board Member Orthopaedics
1994 - 1996 Editorial Board Member Orthopaedics International
Edition
2001 – 2003 Editorial Board Member Orthopaedics and Traumatology
2004 - 2014 Editorial Board Member Clinical Orthopaedics and
Related Research
2005 - Consultant Editor Journal of Orthopaedic Trauma
2005 – 2006 Review Editor Injury
2010 - Editorial Board Member Operative Techniques in
Orthopaedics
2010 - Associate Editor Revista Brasileira de Ortopedia,
Brazil
2010 - Editor-in-Chief Partners Orthopaedic Trauma
Round
2011 Guest Editor Pelvic Fracture Issue
Clinical Orthopaedics and
Related Research
2012 Guest Editor – Tscherne Issue Clinical Orthopaedics and
Related Research
Mark Vrahas, MD
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2015 Guest Editor – Advances in Trauma Operative Techniques
in Orthopaedics
Report of Funded Projects 2009 forward
9/30/09 - 8/31/12 (NCE) Novel, Rapidly Translatable Technologies for Healing
Long Bone Segmental Defects
NIH RCI / AR058776
Co-Investigator ($980,186)
Purpose: The aim of this project was to develop novel, expeditious, biological
approaches to healing large segmental defects that are faster, more effective and less
expensive than existing methods.
2010 – 2011 Fellowship Grant
OMeGA Medical Foundation
Fellowship Director ($31,125).
Purpose: To fund training of a clinical fellow.
2010 – 2011 Graduate Medical Education - Fellowship Grant
Orthopaedic Research and Education Foundation
Fellowship Director ($53,125).
Purpose: To fund training of a clinical fellow.
2010 – 2011 Fellowship Grant
Center for Orthopaedic Trauma Advancement
Fellowship Director ($75,000).
Purpose To fund training of a clinical fellow.
2010 - 2011 Development of Computer Aided Testing for Orthopaedic
Trauma.
Pilot Testing of Bank Items
AO Foundation
PI ($19,500).
Purpose: To find function-related questions (items) that will ultimately comprise a
validated tool for gauging outcomes in Orthopaedic Trauma patients.
2011 - 2012 Fellowship and Education Grant
AO Trauma North America
Fellowship Director ($50,000).
Purpose: To fund training of a clinical fellow.
2011 – 2012 Graduate Medical Education - Fellowship Grant
Orthopaedic Research and Education Foundation
Fellowship Director ($53,038).
Purpose: To fund training of a clinical fellow.
2011 – 2012 Fellowship Grant
Center for Orthopaedic Trauma Advancement
Fellowship Director ($75,000).
Purpose: To fund training of a clinical fellow.
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2010 - 2013 Enhanced Healing of Segmental Bone Defects by
Modulation of the Mechanical Environment
Department of Defense
Consultant (Total Costs - $400,000).
Purpose: Determine effects of changes in mechanical fracture healing
2010 - 2013 Proximal Humerus Fractures in the Elderly
Resident Research Award/Grant – Kanu Okike, MD
OREF
Mentor/Principal Investigator ($50,000).
Purpose: Evaluate clinical outcomes in proximal humeral fractures.
2011 -2013 Evaluation of PROMIS Upper extremity and lower extremity
Physical Function item banks in orthopaedic trauma patients.
AO Foundation
Co-Investigator (CHF 300,000).
Purpose: Evaluate items for physical function item bank.
2011 - 2013 Non-invasive Fasciotomy to Treat Extremity
Compartment Syndrome
CIMIT / Research Award
Co-Investigator ($100,000).
Purpose: Develop method for non-invasive fasciotomy.
2011 – 2013 Radiostereometric Analysis of Fracture Healing in Distal
Femur Fractures
Massachusetts General Hospital – Department of Orthopaedics Grant
Principal Investigator ($50,000).
Purpose: Determine if changes in stress environment measured in vivo using RSA
predicts fracture healing.
1/1/11 – 1/2013 Development of Expedited Bone Healing Technologies
Using Genetically Modified RIA Cells
AO Foundation
Co-Investigator (CHF 115,889)
Purpose: The goal of this work is to develop an improved procedure for healing large
segmental defects in long bones and, by extension, solving other problems in bone
healing by using the RIA to harvest autologous marrow cells.
1/1/12 – 12/31/12 Antimicrobial Photodynamic Therapy for Prevention and
Treatment of Surgical Site Infections
Orthopaedic Trauma Association / Grant #16
Co-PI ($25,000).
Purpose: To test photo therapy for the treatment of infected surgical wounds.
2012 - 2013 Fellowship and Education Grant
AO Trauma North America
Fellowship Director ($50,000).
Purpose: To fund training of a clinical fellow..
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2012 – 2013 Graduate Medical Education - Fellowship Grant
Orthopaedic Research and Education Foundation
Fellowship Director ($26,923).
Purpose: To fund training of a clinical fellow..
2012 – 2013 Fellowship Grant
Center for Orthopaedic Trauma Advancement
Fellowship Director ($75,000).
Purpose: To fund training of a clinical fellow..
Current
2011 – est. 2014 Development of Patient Reported Outcome System
AO Foundation
PI (CHF 1,200,000).
Purpose: To develop a system to facilitate collection of patient reported outcome
measures in clinical practice.
7/1/11 - 6/30/15 Healing of Segmental Defects of Bone by Gene Transfer
NIH / 2R01 AR050243
Consultant ($3,349,250)
Purpose: The proposed research investigates a novel technology for improving the
healing of large bone fractures. The method involves the converting muscle into
bone by transferring a gene encoding bone morphogenetic protein-2 using an
adenovirus.
1/1/12 – 12/31/14 Gene Activated Autologous Tissue Grafts
AO Foundation
Co-Investigator (238,760 CHF).
Purpose. To test gene activated tissues grafts for healing critical sized defects in a
sheep model.
7/3/12 – 7/3/14 Biology-Matched Devices for Medical Applications
DARPA-BAA-11-65 Consultant ($500,000) .
Purpose: To develop novel devices to stabilize injured shoulders for transfer from
the field.
7/1/12 – 6/30/14 Enhanced Bone Formation and Repair by Modification of
Allograft Surfaces
OREF / Synthes Research Grant in Orthopaedic Trauma
Co-PI ($180,000).
Purpose: To determine if different surface characteristics on allographs will enhance bone
healing.
Honors and Prizes
1978-1980 - Alden Scholar, Allegheny College, PA Academic Honors
2000 - Partners in Excellence Award, Partners Healthcare Organizational Excellence
Mark Vrahas, MD
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2001 - Partners in Excellence Award, Partners Healthcare Organizational Excellence
2002 - Kilfoyle Award, New England Orthopaedic Society Resident/Fellow Research
2002- Partners in Excellence Award, Partners Healthcare Organizational Excellence
2002- Golden Apple Teaching Award Harvard Combined Orthopaedic Residency Program
2004- Edwin G. Bovill Jr. Award, OTA - 20th Annual Meeting Outstanding Scientific Paper
2005- Jacquelin Perry Award, Orthopaedic Rehabilitation Society
Academic Specialty Paper
2009- Howard Rosen, M.D. Lecture, NYU Medical Center Contributions in Trauma
2011- Brian A. McGovern, MD, Massachusetts General Hospital
Clinical Excellence Award Nominee
2011- Berton Moed, MD Inaugural Orthopaedic Trauma Lecture –
Contributions in Trauma at Saint Louis Univ.
2011- Honorary Member - DGOU (German Trauma and Orthopaedic Society)
Contributions in Trauma
2012 - Honorary Member _- Asociacion Argentina de Ortopedia y Traumatologia
Contributions in Trauma
2012- Dedication - Annual Orthopaedic Journal Harvard Medical School
Clinical/Research/Educational Leadership
2012- Partners in Excellence Award, Organizational Excellence
(G.I.F.T.S. Program Team Award)
2014- Patricia Mosbacher Honorary Lecture in Orthopaedic Trauma
Contributions in Trauma Hospital for Special Surgery, Cornell Medical Center
2016- National Honor Society, Dartmouth College
Research Grants: 1993 – 1998 Orthopaedic Trauma Association, Grant Funding
Orthopaedic Trauma Association
Member – Reviewer
2003 – 2008 Resident Grants Peer Review Committee
Orthopaedic Research and Education Foundation
Clinician Reviewer
2007 - AO Trauma Research Committee (AOTRC)
AO Foundation
2007 – 2011 Permanent Member
2011 - Acting Representative of AOCID
Mark Vrahas, MD
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2009 Peer Reviewed Orthopaedic Research Program
DoD / SRA International
October 2009 Scientist Reviewer
Peer Reviewed Publications in Print or Other Media
Research Investigations
1. Brown, T.D. & Vrahas, M.S. 1984, "The Apparent Elastic Modulus of the Juxtarticular Subchondral
Bone of the Femoral Head", Journal of Orthopaedic Research: Official Publication of the Orthopaedic
Research Society, vol. 2, no. 1, pp. 32-38.
2. Vrahas, M.S., Brand, R.A., Brown, T.D. & Andrews, J.G. 1990, "Contribution of Passive Tissues to
the Intersegmental Moments at the Hip", Journal of Biomechanics, vol. 23, no. 4, pp. 357-362.
3. Vrahas, M., Gordon, R.G., Mears, D.C., Krieger, D. & Sclabassi, R.J. 1992, "Intraoperative
Somatosensory Evoked Potential Monitoring of Pelvic and Acetabular Fractures", Journal of Orthopaedic
Trauma, vol. 6, no. 1, pp. 50-58.
4. Vrahas, M., Fu, F. & Veenis, B. 1994, "Intraarticular Contact Stresses with Simulated Ankle
Malunions", Journal of Orthopaedic Trauma, vol. 8, no. 2, pp. 159-166.
5. Vrahas, M. & Reid, J.S. 1994, "Simple Intraoperative Traction System for Acetabular Fracture
Surgery", Orthopaedic Review, vol. 23, no. 12, pp. 962, 964-5.
6. Vrahas, M., Hern, T.C., Diangelo, D., Kellam, J. & Tile, M. 1995, "Ligamentous Contributions to
Pelvic Stability", Orthopedics, vol. 18, no. 3, pp. 271-274.
7. Alexander, R.D., Grimm, L. & Vrahas, M.S. 1997, "The Effect of Knee Immobilization on Degree of
Hip Flexion: A Clinical Correlation with Posterior Wall Acetabular Fractures", American Journal of
Orthopedics (Belle Mead, N.J.), vol. 26, no. 5, pp. 345-347.
8. Thomas, K.A., Vrahas, M.S., Noble, J.W.,Jr, Bearden, C.M. & Reid, J.S. 1997, "Evaluation of Hip
Stability after Simulated Transverse Acetabular Fractures", Clinical Orthopaedics and Related Research,
vol. (340), no. 340, pp. 244-256.
9. Vrahas, M.S., Smith, G.A., Rosler, D.M. & Baratta, R.V. 1997, "Method to Impact in vivo Rabbit
Femoral Cartilage with Blows of Quantifiable Stress", Journal of Orthopaedic Research: Official
Publication of the Orthopaedic Research Society, vol. 15, no. 2, pp. 314-317.
10. Wilson, S.C., Vrahas, M.S., Berson, L. & Paul, E.M. 1997, "A Simple Method to Measure
Compartment Pressures Using an Intravenous Catheter", Orthopedics, vol. 20, no. 5, pp. 403-406.
11. Grimm, M.R., Vrahas, M.S. & Thomas, K.A. 1998, "Pressure-Volume Characteristics of the Intact
and Disrupted Pelvic Retroperitoneum", The Journal of Trauma, vol. 44, no. 3, pp. 454-459.
12. Vrahas, M.S., Wilson, S.C., Cummings, P.D. & Paul, E.M. 1998, "Comparison of Fixation Methods
for Preventing Pelvic Ring Expansion", Orthopedics, vol. 21, no. 3, pp. 285-289.
Mark Vrahas, MD
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13. Mazoue, C.G., Guanche, C.A. & Vrahas, M.S. 1999, "Arthroscopic Management of Tibial Plateau
Fractures: An Unselected Series", American Journal of Orthopedics (Belle Mead, N.J.), vol. 28, no. 9, pp.
508-515.
14. Vrahas, M.S., Widding, K.K. & Thomas, K.A. 1999, "The Effects of Simulated Transverse, Anterior
Column, and Posterior Column Fractures of the Acetabulum on the Stability of the Hip Joint", The
Journal of Bone and Joint Surgery, American Volume, vol. 81, no. 7, pp. 966-974.
15. Zhang, H., Vrahas, M.S., Baratta, R.V. & Rosler, D.M. 1999, "Damage to Rabbit Femoral Articular
Cartilage Following Direct Impacts of Uniform Stresses: An in vitro Study", Clinical Biomechanics
(Bristol, Avon), vol. 14, no. 8, pp. 543-548.
16. Kaplan, J.L., Wright, M.J., Lazarus, L., Congemi, N., duTreil, K., Arnold, R., Mercante, D., Diaz,
J.H., Vrahas, M. & Hunt, J.P. 2000, "Use of an Unmanned Police Car to Reduce Traffic Speed", The
Journal of Trauma, vol. 49, no. 1, pp. 43-46.
17. Stubbs, M., Zhang, H., Vrahas, M.S., Baratta, R.V. & Zieske, A. 2000, "Effect of Intraarticular
Stainless Steel Implants on the Health of the Rabbit Knee Joint: An Experimental Study", Journal of
Orthopaedic Trauma, vol. 14, no. 8, pp. 567-570.
18. Dickson, K.F., Galland, M.W., Barrack, R.L., Neitzschman, H.R., Harris, M.B., Myers, L. & Vrahas,
M.S. 2002, "Magnetic Resonance Imaging of the Knee after Ipsilateral Femur Fracture", Journal of
Orthopaedic Trauma, vol. 16, no. 8, pp. 567-571.
19. Wood, S.P., Vrahas, M. & Wedel, S.K. 2003, "Femur Fracture Immobilization with Traction Splints
in Multisystem Trauma Patients", Prehospital Emergency Care: Official Journal of the National
Association of EMS Physicians and the National Association of State EMS Directors, vol. 7, no. 2, pp.
241-243.
20. Bhattacharyya, T. & Vrahas, M.S. 2004, "The Medical-Legal Aspects of Compartment Syndrome",
The Journal of Bone and Joint Surgery, American Volume, vol. 86-A, no. 4, pp. 864-868.
21. Mithofer, K., Lhowe, D.W., Vrahas, M.S., Altman, D.T. & Altman, G.T. 2004, "Clinical Spectrum of
Acute Compartment Syndrome of the Thigh and its Relation to Associated Injuries", Clinical
Orthopaedics and Related Research, vol. (425), no. 425, pp. 223-229.
22. Murray, M.M., Zurakowski, D. & Vrahas, M.S. 2004, "The Death of Articular Chondrocytes after
Intra-articular Fracture in Humans", The Journal of Trauma, vol. 56, no. 1, pp. 128-131.
23. Bhattacharyya, T., McCarty, L.P.,3rd, Harris, M.B., Morrison, S.M., Wixted, J.J., Vrahas, M.S. &
Smith, R.M. 2005, "The Posterior Shearing Tibial Plateau Fracture: Treatment and Results via a Posterior
Approach", Journal of Orthopaedic Trauma, vol. 19, no. 5, pp. 305-310.
24. Bhattacharyya, T., Levin, R., Vrahas, M.S. & Solomon, D.H. 2005, "Nonsteroidal Anti-inflammatory
Drugs and Nonunion of Humeral Shaft Fractures", Arthritis and Rheumatism, vol. 53, no. 3, pp. 364-367.
25. Bhattacharyya, T., Crichlow, R., Gobezie, R., Kim, E. & Vrahas, M.S. 2006, "Complications
Associated with the Posterolateral Approach for Pilon Fractures", Journal of Orthopaedic Trauma, vol. 20,
no. 2, pp. 104-107.
Mark Vrahas, MD
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26. Bhattacharyya, T., Vrahas, M.S., Morrison, S.M., Kim, E., Wiklund, R.A., Smith, R.M. & Rubash,
H.E. 2006, "The Value of the Dedicated Orthopaedic Trauma Operating Room", The Journal of Trauma,
vol. 60, no. 6, pp. 1336-40; discussion 1340-1.
27. Betz, O.B., Betz, V.M., Nazarian, A., Pilapil, C.G., Vrahas, M.S., Bouxsein, M.L., Gerstenfeld, L.C.,
Einhorn, T.A. & Evans, C.H. 2006, "Direct Percutaneous Gene Delivery to Enhance Healing of
Segmental Bone Defects", The Journal of Bone and Joint Surgery, American Volume, vol. 88, no. 2, pp.
355-365.
28. Crichlow, R.J., Andres, P.L., Morrison, S.M., Haley, S.M. & Vrahas, M.S. 2006, "Depression in
Orthopaedic Trauma Patients, Prevalence and Severity", The Journal of Bone and Joint Surgery,
American Volume, vol. 88, no. 9, pp. 1927-1933.
29. Mithoefer, K., Lhowe, D.W., Vrahas, M.S., Altman, D.T., Erens, V. & Altman, G.T. 2006,
"Functional Outcome After Acute Compartment Syndrome of the Thigh", The Journal of Bone and Joint
Surgery, American Volume, vol. 88, no. 4, pp. 729-737.
30. O'Toole, R.V., Gobezie, R., Hwang, R., Chandler, A.R., Smith, R.M., Estok, D.M.,2nd & Vrahas,
M.S. 2006, "Low Complication Rate of LISS for Femur Fractures Adjacent to Stable Hip or Knee
Arthroplasty", Clinical Orthopaedics and Related Research, vol. 450, pp. 203-210.
31. Betz, V.M., Betz, O.B., Glatt, V., Gerstenfeld, L.C., Einhorn, T.A., Bouxsein, M.L., Vrahas, M.S. &
Evans, C.H. 2007, "Healing of Segmental Bone Defects by Direct Percutaneous Gene Delivery: Effect of
Vector Dose", Human Gene Therapy, vol. 18, no. 10, pp. 907-915.
32. Betz, O.B., Betz, V.M., Nazarian, A., Egermann, M., Gerstenfeld, L.C., Einhorn, T.A., Vrahas, M.S.,
Bouxsein, M.L. & Evans, C.H. 2007, "Delayed Administration of Adenoviral BMP-2 Vector Improves
the Formation of Bone in Osseous Defects", Gene Therapy, vol. 14, no. 13, pp. 1039-1044.
33. Rightmire, E., Zurakowski, D. & Vrahas, M. 2008, "Acute Infections After Fracture Repair:
Management with Hardware in Place", Clinical Orthopaedics and Related Research, vol. 466, no. 2, pp.
466-472.
34. Chakraverty, J.K., Weaver, M.J., Smith, R.M. & Vrahas, M.S. 2009, "Surgical Management of Tibial
Tubercle Fractures in Association with Tibial Plateau Fractures Fixed by Direct Wiring to a Locking
Plate", Journal of Orthopaedic Trauma, vol. 23, no. 3, pp. 221-225.
35. Evans, C.H., Liu, F.J., Glatt, V., Hoyland, J.A., Kirker-Head, C., Walsh, A., Betz, O., Wells, J.W.,
Betz, V., Porter, R.M., Saad, F.A., Gerstenfeld, L.C., Einhorn, T.A., Harris, M.B. & Vrahas, M.S. 2009,
"Use of Genetically Modified Muscle and Fat Grafts to Repair Defects in Bone and Cartilage", European
Cells & Materials, vol. 18, pp. 96-111.
36. Glatt, V., Kwong, F.N., Park, K., Parry, N., Griffin, D., Vrahas, M., Evans, C.H. & Harris, M. 2009,
"Ability of Recombinant Human Bone Morphogenetic Protein 2 to Enhance Bone Healing in the Presence
of Tobramycin: Evaluation in a Rat Segmental Defect Model", Journal of Orthopaedic Trauma, vol. 23,
no. 10, pp. 693-701.
37. Porter, R.M., Liu, F., Pilapil, C., Betz, O.B., Vrahas, M.S., Harris, M.B. & Evans, C.H. 2009,
"Osteogenic Potential of Reamer Irrigator Aspirator (RIA) Aspirate Collected from Patients Undergoing
Hip Arthroplasty", Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research
Society, vol. 27, no. 1, pp. 42-49.
Mark Vrahas, MD
Page 15
38. Bachoura, A., Guitton, T.G., Smith, R.M., Vrahas, M.S., Zurakowski, D. & Ring, D. 2011, "Infirmity
and Injury Complexity are Risk Factors for Surgical-site Infection after Operative Fracture Care", Clinical
Orthopaedics and Related Research, vol. 469, no. 9, pp. 2621-2630.
39. Banffy, M.B., Vrahas, M.S., Ready, J.E. & Abraham, J.A. 2011, "Nonoperative Versus Prophylactic
Treatment of Bisphosphonate-Associated Femoral Stress Fractures", Clinical Orthopaedics and Related
Research, vol. 469, no. 7, pp. 2028-2034.
40. Liu, W., Liu, F., Zhao, W., Kim, J.M., Wang, Z. & Vrahas, M.S. 2011, "Osteochondral Autograft
Transplantation for Acute Osteochondral Fractures Associated with an Ankle Fracture", Foot & Ankle
International/American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society, vol. 32,
no. 4, pp. 437-442.
41. Miller, M.A., Ivkovic, A., Porter, R., Harris, M.B., Estok, D.M., 2nd, Smith, R.M., Evans, C.H. &
Vrahas, M.S. 2011, "Autologous Bone Grafting on Steroids: Preliminary Clinical Results. A Novel
Treatment for Nonunions and Segmental Bone Defects", International Orthopaedics, vol. 35, no. 4, pp.
599-605.
42. Weaver, M.J., Harris, M.B., Strom, A.C., Smith, R.M., Lhowe, D., Zurakowski, D. & Vrahas, M.S.
2011, "Fracture Pattern and Fixation Type Related to Loss of Reduction in Bicondylar Tibial Plateau
Fractures", Injury.
43. Wiggers, J.K., Guitton, T.G., Smith, R.M., Vrahas, M.S. & Ring, D. 2011, "Observed and Expected
Outcomes in Transfer and Nontransfer Patients with a Hip Fracture", Journal of Orthopaedic Trauma, vol.
25, no. 11, pp. 666-669.
44. Dai, T., Vrahas, M.S., Murray, C.K. & Hamblin, M.R. 2012, "Ultraviolet C irradiation: An
Alternative Antimicrobial Approach to Localized Infections?", Expert Review of Anti-infective Therapy,
vol. 10, no. 2, pp. 185-195.
45. Weaver, M.J., Harris, M.B., Strom, A.C., Smith, R.M., Lhowe, D., Zurakowski, D., & Vrahas, M.S.
2012, “Fracture Patter and Fixation Type Related to Loss of Reduction in Bicondylar Tibial Plateau
Fractures”, Injury: International=-098212345678Journal of the Care of the Injured, vol. 43, pp. 864-869.
46. Weaver, M.J., Bruinsma, W., Toney, E., Dafford, E., & Vrahas, M.S. 2012, “What Are the Patterns
of Injury and Displacement Seen in Lateral Compression Pelvic Fractures”, Clinical Orthopaedics and
Related Research, vol. 470, no. 5, [online]
47. Miller, M.A., Liu, W., Zurakowski, D., Smith, R.M., Harris, M.B., & Vrahas, M.S. 2012, "Factors
Predicting Failure of Patella Fixation.", The Journal of Trauma and Acute Care Surgery, vol. 72, no. 4,
pp. 1051-1055.
48. Moed, B.R., & Vrahas, M.S. 2012, "Disruptions of the Pelvic Ring: An Update: Editorial
Comment." Clinical Orthopaedics & Related Research, vol. 470, no. 8, pp. 2073-2074.
49. Glatt, V., Miller, M.A., Ivkovic, A., Liu, F., Parry, N., Griffin, D., Vrahas, M.S., & Evans, C.H.
2012, “Improved Healing of Large Segmental Defects in the Rat Femur by Reverse Dynamization in the
Presence of Bone Morphogenetic Protein-2”, The Journal of Bone & Joint Surgery, vol. 94, no. 22
Mark Vrahas, MD
Page 16
50. Dai, T., Murray, C.K., Vrahas, M.S., Baer, D.G., Tegos, G.P., & Hamblin, M.R. 2012, "Ultraviolet
C light for Acinetobacter Baumannii Wound Infections in Mice: Potential Use for Battlefield Wound
Decontamination?", The Journal of Trauma and Acute Care Surgery, vol. 73, no. 3, pp. 661-667.
51. Dai, T., Garcia, B., Murray, C.K., Vrahas, M.S., & Hamblin, M.R. 2012, "UVC Light Prophylaxis
for Cutaneous Wound Infections in Mice", Antimicrobial Agents & Chemotherapy, vol. 56, no. 7, pp.
3841-3848.
52. Okike, K., Lee, O.C., Makanji, H., Harris, M.B., Vrahas, M.S. 2012, “Factors Associated with the
Decision for Operative versus Non-operative Treatment of Displaced Proximal Humerus Fractures in the
Elderly”, Injury, Apr; 44(4):448-55. doi: 10.1016/j.injury.2012.09.002. Epub 2012 Sep 27.
53. Dai, T., Gupta, A., Huang, Y-Y., Sherwood, M., Murray, C., Vrahas, M.S., Kielian, T., Hamblin,
M.R. 2013, “Blue Light Eliminates Community-Acquired Methicillin-Resistant Staphylococcus Aureus
in Infected Mouse Skin Abrasions”, Photomedicine and Laser Surgery, doi: 10.1089/pho.2012.3365,
Epub 2013 Feb.
54. Liu W, Liu F, Zhao W, Kim JM, Wang Z, Vrahas MS. Osteochondral autograft transplantation for
acute osteochondral fractures associated with an ankle fracture. Foot Ankle Int. 2011;4:437-442.
54. Wiggers JK, Guitton TG, Smith RM, Vrahas MS, Ring D. Observed and expected outcomes in
transfer and nontransfer patients with a hip fracture. J Orthop Trauma. 2011;11:666-669.
55. Bachoura A, Guitton TG, Smith RM, Vrahas MS, Zurakowski D, Ring D. Infirmity and injury
complexity are risk factors for surgical-site infection after operative fracture care. Clin Orthop.
2011;9:2621-2630.
56. Dai T, Garcia B, Murray CK, Vrahas MS, Hamblin MR. UVC light prophylaxis for cutaneous wound
infections in mice. Antimicrob Agents Chemother. 2012;7:3841-3848
57. Helmerhorst GT, Lindenhovius AL, Vrahas M, Ring D, Kloen P. Satisfaction with pain relief after
operative treatment of an ankle fracture. Injury. 2012;11:1958-1961.
58. Weaver MJ, Harris MB, Strom AC, Smith RM, Lhowe D, Zurakowski D, Vrahas MS. Fracture
pattern and fixation type related to loss of reduction in bicondylar tibial plateau fractures. Injury.
2012;6:864-869.
59. Miller MA, Liu W, Zurakowski D, Smith RM, Harris MB, Vrahas MS. Factors predicting failure of
patella fixation. J Trauma Acute Care Surg. 2012;4:1051-1055.
60. Dai T, Murray CK, Vrahas MS, Baer DG, Tegos GP, Hamblin MR. Ultraviolet C light for
acinetobacter baumannii wound infections in mice: Potential use for battlefield wound decontamination?.
J Trauma Acute Care Surg. 2012;3:661-667.
61. Dai T, Gupta A, Murray CK, Vrahas MS, Tegos GP, Hamblin MR. Blue light for infectious diseases:
Propionibacterium acnes, helicobacter pylori, and beyond?. Drug Resist Updat. 2012;4:223-236.
62. Weaver MJ, Bruinsma W, Toney E, Dafford E, Vrahas MS. What are the patterns of injury and
displacement seen in lateral compression pelvic fractures?. Clin Orthop. 2012;8:2104-2110.
63. Glatt V, Miller M, Ivkovic A, Liu F, Parry N, Griffin D, Vrahas M, Evans C. Improved healing of
large segmental defects in the rat femur by reverse dynamization in the presence of bone morphogenetic
protein-2. J Bone Joint Surg Am. 2012;22:2063-2073.
Mark Vrahas, MD
Page 17
64. Dai T, Gupta A, Huang YY, Yin R, Murray CK, Vrahas M, Sherwood ME, Tegos GP, Hamblin MR.
Blue light rescues mice from potentially fatal pseudomonas aeruginosa burn infection: Efficacy, safety,
and mechanism of action. Antimicrob Agents Chemother. 2013;3:1238-1245.
65. Dai T, Gupta A, Huang YY, Yin R, Murray CK, Vrahas M, Sherwood ME, Tegos GP, Hamblin MR.
Blue light rescues mice from potentially fatal pseudomonas aeruginosa burn infection: Efficacy, safety,
and mechanism of action. Antimicrob Agents Chemother. 2013;3:1238-1245.
66. Fayaz HC, Haas N, Kellam J, Bavonratanavech S, Parvizi J, Dyer G, Pohlemann T, Jerosch J,
Prommersberger KJ, Pape HC, Smith M, Vrahas M, Perka C, Siebenrock K, Elhassan B, Moran C,
Jupiter JB. Improvement of research quality in the fields of orthopaedics and trauma: A global
perspective. Int Orthop. 2013;7:1205-1212.
67. Ferreira E, Porter RM, Wehling N, O'Sullivan RP, Liu F, Boskey A, Estok DM, Harris MB, Vrahas
MS, Evans CH, Wells JW. Inflammatory cytokines induce a unique mineralizing phenotype in
mesenchymal stem cells derived from human bone marrow. J Biol Chem. 2013;41:29494-29505.
68. Liu W, Zhou D, Liu F, Weaver MJ, Vrahas MS. Mechanical complications of intertrochanteric hip
fractures treated with trochanteric femoral nails. J Trauma Acute Care Surg. 2013;2:304-310.
69. Menendez ME, Neuhaus V, Bot AG, Vrahas MS, Ring D. Do psychiatric comorbidities influence
inpatient death, adverse events, and discharge after lower extremity fractures?. Clin Orthop.
2013;10:3336-3348.
70. Okike K, Lee OC, Makanji H, Harris MB, Vrahas MS. Factors associated with the decision for
operative versus non-operative treatment of displaced proximal humerus fractures in the elderly. Injury.
2013;4:448-455.
71. Thomas SH, Arthur AO, Howard Z, Shear ML, Kadzielski JL, Vrahas MS. Helicopter emergency
medical services crew administration of antibiotics for open fractures. Air Med J. 2013;2:74-79.
72. Van Kollenburg JA, Vrahas MS, Smith RM, Guitton TG, Ring D, Science of Variation G. Diagnosis
of union of distal tibial fractures: Accuracy and interobserver reliability. Injury, 2013;8:1073-1075
73. Helmerhorst GT, Vranceanu AM, Vrahas M, Smith M, Ring D, Risk factors for continued opioid
use one to two months after surgery for musculoskeletal trauma. J Bone Joint Surg Am. 2014; 6:495-499.
74. Kleweno C, Morgan J, Redshaw J, Harris M, Rodriguez E, Zurakowski D, Vrahas M, Appleton P
Short versus long cephalomedullary nails for the treatment of intertrochanteric hip fractures in patients
older than 65 years. J Orthop Trauma. 2014; 7:391-397
75. Vranceanu AM, Bachoura A, Weening A, Vrahas M, Smith RM, Ring D. Psychological factors
predict disability and pain intensity after skeletal trauma. J Bone Joint Surg Am. 2014;3 e20.
76. Zhang Y, Zhu Y, Gupta A, Huang Y, Murray CK, Vrahas MS, Sherwood ME, Baer DG, Hamblin
MR, Dai T, Antimicrobial blue light therapy for multidrug-resistant acinetobacter baumannii infection in
a mouse burn model: Implications for prophylaxis and treatment of combat-related wound infections. J
Infect Dis. 2014; 12: 1963-1971
77. Liu W, Wang J, Weaver MJ, Vrahas MS, Zhou D. Lateral Migration with telescoping of a
trochanteric fixation nail in the treatment of an intertrochanteric hip fracture. Chinese Medicine Journal.
2014; 127 (4); 680-4
Mark Vrahas, MD
Page 18
78. Rodriguez EK, Boulton C, Weaver MJ, Herder LM, Morgan JH, Chacko AT, Appleton PT,
Zurakowski D, Vrahas MS. Predictive factors of distal femoral facture nonunion after lateral locked
plating: a retrospective multicenter case-control study of 283 fractures. Injury. 2014 March; 45 (3): 554-9.
Doi: 10.1016/j.injury.2013.10.042. Epub2013 Nov 4
79. Ting BL, Heng M, Vrahas MS, Rodriguez EK, Harris MB, Weaver MJ. Is Disuse Osteopenia a
Favorable Prognostic Sign After Femoral Neck Fracture? J. Orthop Trauma 2016 Sep;30(9):496-502. doi:
10.1097/BOT.0000000000000635.
80. Grodzinsky AJ, Wang Y, Kakar S, Vrahas MS, Evans CH.
Intra-articular dexamethasone to inhibit the development of post-traumatic osteoarthritis.
J Orthop Res. 2016 May 13. doi: 10.1002/jor.23295. [Epub ahead of print] Review.
81. Liu F, Wells JW, Porter RM, Glatt V, Shen Z, Schinhan M, Ivkovic A, Vrahas MS, Evans CH,
Ferreira E. Interaction between living bone particles and rhBMP-2 in large segmental defect healing in the
rat femur. J Orthop Res. 2016 Apr 2. doi: 10.1002/jor.23255. [Epub ahead of print]
82. Rodriguez EK, Zurakowski D, Herder L, Hall A, Walley KC, Weaver MJ, Appleton PT, Vrahas M.
Mechanical Construct Characteristics Predisposing to Non-union After Locked Lateral Plating of Distal
Femur Fractures. J Orthop Trauma. 2016 Aug;30(8):403-8. doi:
83. von Keudell A, Vrahas MS, Weaver MJ. Surgical Versus Nonsurgical Treatment of Adults With
Displaced Fractures of the Proximal Humerus: The PROFHER Randomized Clinical Trial.
J Orthop Trauma. 2016 Apr;30(4):e143. doi: 10.1097/BOT.0000000000000550.
84. Patel SP, Antoci V Jr, Kadzielski JJ, Vrahas MS. Exactech Opteon Femoral Component Fracture 12
Years after Arthroplasty. Case Rep Orthop. 2016;2016:1789197. doi: 10.1155/2016/1789197. Epub 2016
Feb 3.
85. Zhang Y, Zhu Y, Chen J, Wang Y, Sherwood ME, Murray CK, Vrahas MS, Hooper DC, Hamblin
MR, Dai T. Antimicrobial blue light inactivation of Candida albicans: In vitro and in vivo studies.
Virulence. 2016 Jul 3;7(5):536-45. doi: 10.1080/21505594.2016.1155015. Epub 2016 Feb 24.
86. von Keudell AG, Weaver MJ, Appleton PT, Bae DS, Dyer GS, Heng M, Jupiter JB, Vrahas
MS.Lancet Diagnosis and treatment of acute extremity compartment syndrome. 2015 Sep
26;386(10000):1299-310. doi: 10.1016/S0140-6736(15)00277-9. Review. Erratum in: Lancet. 2015 Nov
7;386(10006):1824. Appelton, Paul T [corrected to Appleton, Paul T]. Lancet. 2015 Nov
7;386(10006):1824.
87. van Dijk PA, Bot AG, Neuhaus V, Menendez ME, Vrahas MS, Ring D. Admission From Nursing
Home Residence Increases Acute Mortality After Hip Fractures. Geriatr Orthop Surg Rehabil. 2015
Sep;6(3):123-9. doi: 10.1177/2151458515570477.
88. Babu S, Sandiford NA, Vrahas M. Use of Teriparatide to improve fracture healing: What is the
evidence? World J Orthop. 2015 Jul 18;6(6):457-61. doi: 10.5312/wjo.v6.i6.457. eCollection 2015 Jul 18.
89. Morgan JH, Kallen MA, Okike K, Lee OC, Vrahas MS.PROMIS Physical Function Computer
Adaptive Test Compared With Other Upper Extremity Outcome Measures in the Evaluation of Proximal
Humerus Fractures in Patients Older Than 60 Years. J Orthop Trauma. 2015 Jun;29(6):257-63. doi:
10.1097/BOT.0000000000000280.
Mark Vrahas, MD
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90. Gardner S, Weaver MJ, Jerabek S, Rodriguez E, Vrahas M, Harris M. Predictors of early failure in
young patients with displaced femoral neck fractures. J Orthop. 2014 Feb 7;12(2):75-80. doi:
10.1016/j.jor.2014.01.001. eCollection 2015 Jun.
91. Okike K, Lee OC, Makanji H, Morgan JH, Harris MB, Vrahas MS. Comparison of locked plate
fixation and nonoperative management for displaced proximal humerus fractures in elderly patients.
Am J Orthop (Belle Mead NJ). 2015 Apr;44(4):E106-12.
92. Moed BR, Kregor PJ, Reilly MC, Stover MD, Vrahas MS. Current management of posterior wall
fractures of the acetabulum. Instr Course Lect. 2015;64:139-59. Review.
93. Vranceanu AM, Hageman M, Strooker J, ter Meulen D, Vrahas M, Ring D. A preliminary RCT of a
mind body skills based intervention addressing mood and coping strategies in patients with acute
orthopaedic trauma. Injury. 2015 Apr;46(4):552-7. doi: 10.1016/j.injury.2014.11.001. Epub 2014 Nov 10.
94. Voskuijl T, Neuhaus V, Kinaci A, Vrahas M, Ring D. In-Hospital Outcomes after Hemiarthroplasty
versus Total Hip Arthroplasty for Isolated Femoral Neck Fractures. Arch Bone Jt Surg. 2014
Sep;2(3):151-6. Epub 2014 Sep 15.
95. Weaver MJ, Brubacher JW, Vrahas MS. Application of epoxy resin to a solid-foam pelvic model:
creating a dry-erase pelvis. Am J Orthop (Belle Mead NJ). 2014 Nov;43(11):521-3.
96. Beamer BS, Morgan JH, Barr C, Weaver MJ, Vrahas MS. Does fluoroscopy improve acetabular
component placement in total hip arthroplasty? Clin Orthop Relat Res. 2014 Dec;472(12):3953-62. doi:
10.1007/s11999-014-3944-8. Epub 2014 Sep 20.
97. Gitajn IL, Abousayed M, Toussaint RJ, Vrahas M, Kwon JY. Calcaneal avulsion fractures: a case
series of 33 patients describing prognostic factors and outcomes. Foot Ankle Spec. 2015 Feb;8(1):10-7.
doi: 10.1177/1938640014548323. Epub 2014 Sep 8.
98. Toussaint RJ, Bergeron SG, Weaver MJ, Tornetta P 3rd, Vrahas MS, Harris MB. The effect of the
Massachusetts healthcare reform on the uninsured rate of the orthopaedic trauma population.
J Bone Joint Surg Am. 2014 Aug 20;96(16):e141. doi: 10.2106/JBJS.M.00740.
Other Peer-Reviewed Publications
1. Vrahas, M.S. 1994, "Prophylaxis of Deep Vein Thrombosis in Trauma Patients", Orthopedics, vol. 17
Suppl, pp. 21-23.
2. Vrahas, M.S. & Reid, J.S. 1994, "Late Recognition of a Rectal Tear Associated with a Pelvic Fracture.
A Case Report", The Journal of Bone and Joint Surgery, American Volume, vol. 76, no. 7, pp. 1072-1076.
3. Vrahas, M. 1995, "Examining trends", Orthopedics, vol. 18, no. 7, pp. 609. Henry, B.J. & Vrahas,
M.S. 1996, "The Thomas Splint. Questionable Boast of an Indispensable Tool", American Journal of
Orthopedics (Belle Mead, N.J.), vol. 25, no. 9, pp. 602-604.
4. Segal, L.S., Vrahas, M.S. & Schwentker, E.P. 1996, "Dysplasia Epiphysealis Hemimelica of the
Sacroiliac Joint: a Case Report", Clinical Orthopaedics and Related Research, vol. (333), no. 333, pp.
202-207.
Mark Vrahas, MD
Page 20
5. Jimenez, M.L. & Vrahas, M.S. 1997, "Surgical Approaches to the Acetabulum", The Orthopedic
Clinics of North America, vol. 28, no. 3, pp. 419-434.
6. David, T.S. & Vrahas, M.S. 2000, "Perioperative Lower Urinary Tract Infections and Deep Sepsis in
Patients Undergoing Total Joint Arthroplasty", The Journal of the American Academy of Orthopaedic
Surgeons, vol. 8, no. 1,
pp. 66-74.
7. Bharam, S., Vrahas, M.S. & Fu, F.H. 2002, "Knee Fractures in the Athlete", The Orthopedic Clinics of
North America, vol. 33, no. 3, pp. 565-574.
8. Giza, E., Mithofer, K., Matthews, H. & Vrahas, M. 2004, "Hip Fracture-Dislocation in Football: a
Report of Two Cases and Review of the Literature", British Journal of Sports Medicine, vol. 38, no. 4, pp.
E17.
9. Mithofer, K., Gill, T.J. & Vrahas, M.S. 2004, "Tibial Plateau Fracture Following Anterior Cruciate
Ligament Reconstruction", Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the
ESSKA, vol. 12, no. 4, pp. 325-328.
10. Vrahas, M.S., Mithoefer, K. & Joseph, D. 2004, "The Long-Term Effects of Articular Impaction",
Clinical Orthopaedics and Related Research, vol. (423), no. 423, pp. 40-43.
11. Mithoefer, K., Gill, T.J. & Vrahas, M.S. 2005, "Supracondylar Femoral Fracture after Arthroscopic
Reconstruction of the Anterior Cruciate Ligament. A Case Report", The Journal of Bone and Joint
Surgery, American Volume, vol. 87, no. 7, pp. 1591-1596.
12. Bosse, M.J., Henley, M.B., Bray, T. & Vrahas, M.S. 2006, "An AOA Critical Issue - Access to
Emergent Musculoskeletal Care: Resuscitating Orthopaedic Emergency-Department Coverage", The
Journal of Bone and Joint Surgery, American Volume, vol. 88, no. 6, pp. 1385-1394.
13. Dyer, G.S. & Vrahas, M.S. 2006, "Review of the Pathophysiology and Acute Management of
Hemorrhage in Pelvic Fracture", Injury, vol. 37, no. 7, pp. 602-613.
14. Price, M.D., Padera, R.F., Harris, M.B. & Vrahas, M.S. 2006, "Case Reports: Pathologic Fracture of
the Patella from a Gouty Tophus", Clinical Orthopaedics and Related Research, vol. 445, pp. 250-253.
15. Evans, C.H., Palmer, G.D., Pascher, A., Porter, R., Kwong, F.N., Gouze, E., Gouze, J.N., Liu, F.,
Steinert, A., Betz, O., Betz, V., Vrahas, M. & Ghivizzani, S.C. 2007, "Facilitated Endogenous Repair:
Making Tissue Engineering Simple, Practical, and Economical", Tissue Engineering, vol. 13, no. 8, pp.
1987-1993.
16. Vrahas, M.S. 2007, "Acute Care Surgery from the Orthopedic Surgeon's Perspective: a Lost
Opportunity", Surgery, vol. 141, no. 3, pp. 317-320.
17. Betz, V.M., Betz, O.B., Harris, M.B., Vrahas, M.S. & Evans, C.H. 2008, "Bone Tissue Engineering
and Repair by Gene Therapy", Frontiers in Bioscience: a Journal and Virtual Library, vol. 13, pp. 833-
841.
18. Lindenhovius, A.L., Helmerhorst, G.T., Schnellen, A.C., Vrahas, M., Ring, D. & Kloen, P. 2009,
"Differences in Prescription of Narcotic Pain Medication after Operative Treatment of Hip and Ankle
Fractures in the United States and The Netherlands", The Journal of Trauma, vol. 67, no. 1, pp. 160-164.
Mark Vrahas, MD
Page 21
19. Davidovitch, R.I., Jordan, C.J., Egol, K.A. & Vrahas, M.S. 2010, "Challenges in the Treatment of
Femoral Neck Fractures in the Nonelderly Adult", The Journal of Trauma, vol. 68, no. 1, pp. 236-242.
20. Kadzielski, J. & Vrahas, M. 2010, "A Vascular Complication of Trochanteric-Entry Femoral Nailing
on a Fracture Table", American Journal of Orthopedics (Belle Mead, N.J.), vol. 39, no. 7, pp. E64-6.
21. Moed, B.R., Dickson, K.F., Kregor, P.J., Reilly, M.C. & Vrahas, M.S. 2010, "The Surgical Treatment
of Acetabular Fractures", Instructional Course Lectures, vol. 59, pp. 481-501.
22. Weaver, M.J., Miller, M.A. & Vrahas, M.S. 2010, "The Orthopaedic Implications of Diphosphonate
Therapy", The Journal of the American Academy of Orthopaedic Surgeons, vol. 18, no. 6, pp. 367-374.
23. Fayaz, H.C., Giannoudis, P.V., Vrahas, M.S., Smith, R.M., Moran, C., Pape, H.C., Krettek, C. &
Jupiter, J.B. 2011, "The Role of Stem Cells in Fracture Healing and Nonunion", International
Orthopaedics, vol. 35, no. 11, pp. 1587-1597.
24. Hacking SA, Vrahas MS. Toward a new standard in autogenous bone graft?: Commentary on an
article by H. claude sagi, MD, et al.: "qualitative and quantitative differences between bone graft obtained
from the medullary canal (with a Reamer/Irrigator/Aspirator) and the iliac crest of the same patient". J
Bone Joint Surg Am. 2012;23:e1801-2.
25. Maliha G, Morgan J, Vrahas M. Transient osteoporosis of pregnancy. Injury. 2012;8:1237-1241.
26. Moed BR, Vrahas MS. Disruptions of the pelvic ring: An update: Editorial comment. Clin Orthop.
2012;8:2073-2074.
27. Hacking SA, Vrahas MS. Toward a new standard in autogenous bone graft?: Commentary on an
article by H. claude sagi, MD, et al.: "qualitative and quantitative differences between bone graft obtained
from the medullary canal (with a Reamer/Irrigator/Aspirator) and the iliac crest of the same patient". J
Bone Joint Surg Am. 2012;23:e1801-2.
Research Publications without Named Authorship
1. Russell, T.A., Leighton, R.K. & Alpha-BSM Tibial Plateau Fracture Study Group 2008,
"Comparison of Autogenous Bone Graft and Endothermic Calcium Phosphate Cement for Defect
Augmentation in Tibial Plateau Fractures - A Multicenter, Prospective, Randomized Study", The
Journal of Bone and Joint Surgery. American Volume, vol. 90, no. 10, pp. 2057-2061.
Non-peer reviewed scientific or medical publications/materials in print or other media
Reviews, Chapters, Monographs and Editorials
1. Vrahas MS. Pelvic Fractures: External Fixation. In: Wiss DA, editor. Master Techniques in
Orthopaedic Surgery: Fractures. Philadelphia: Lippincott Publishing; 1998. p. 569-582.
2. Vrahas MS, Tile M. Fractures of the Acetabulum. In: Bucholz RW, Heckman JD, editors.
Rockwood and Green’s Fractures in Adults, 5th Edition. Philidelphia: Lippincott Williams & Wilkins;
2001. vol. 2, p. 1513-1546.
Mark Vrahas, MD
Page 22
3. Vrahas MS. Diastasis of the Symphysis Pubis: Open Reduction Internal Fixation. In: Wiss DA,
editor. Master Techniques in Orthopaedic Surgery: Fractures. Philadelphia: Lippincott Publishing; 1998.
p. 583-594.
4. Tile M, Hearn T, Vrahas MS. Biomechanics of the Pelvic Ring. In: Tile M, Helfet DL, Kellam JF,
editors. Fractures of the Pelvis and Acetabulum, Third Edition. Philadelphia: Lippincott Williams &
Wilkins; 2004. p. 32-45.
5. Vrahas MS, Jospeh D. Orthopaedic Trauma 2: Pelvic Fractures. In: Sheridan RL, Lhowe LC,
editors. The Trauma Handbook of the Massachusetts General Hospital. Philadelphia: Lippincott
Williams & Wilkins; 2004.
6. Cooper J, Vrahas M. Classification and Biomechanics of Pelvic Ring Injuries. In: Brinker M, editor.
Review of Orthopaedic Trauma. Philadelphia: W.B. Saunders Company; 2011. 10.
7. Moed BR, Dickson K, Kregor P, Reilly M, Vrahas M. The Surgical Treatment of Acetabular
Fractures. In: Ricci WM, Tornetta III P, editors. AAOS Instructional Course Lectures – Trauma 2.
Rosemont, IL: Orthopaedic Trauma Association, 2012. Chapter 10.
8. Pape HC, Vrahas MS. Symposium: Tscherne festschrift: Editorial comment. Clin Orthop.
2013;9:2751-2752.
Professional educational materials or reports, in print or other media
1. Gorczyca J, Jimenez M, Vrahas M. Selective Exposures in Orthopaedic Surgery: The Pelvis. AAOS,
Instructional Video, Spring 2005.
Abstracts, Poster Presentations and Exhibits Presented at Professional Meetings
1. Liu F, Ferreira E, Porter RM, Glatt V, Ivkovic A, Wells J, Vrahas M, Evans C. Synergy Between
Living Bone Particles and rhBMP-2 in the Healing of Large Segmental Defects in the Rat Femur.
Transactions of the Orthopaedic Research Society, Vol. 37. 2012; San Francisco, CA.
2. Toussaint RJ, Bergeron S, Weaver M, Tornetta P, Vrahas MS, Harris MB. Massachusetts Health
Care Reform: Its Effect on the Percentage of Uninsured Patients and the Reimbursement for Providers at
Academic Level One Trauma Centers. Poster Presentation – Orthopaedic Trauma Association Annual
Meeting; 2012 Oct 3-6; Minneapolis, MN.
3. Gardner S, Weaver M, Jerabek S, Vrahas MS, Appleton P, Harris MB. Displace Femoral Neck
Fractures in Patients Less Than 60 Years of Age. Paper Presentation – Orthopaedic Trauma Association
Annual Meeting; 2012 Oct 3-6; Minneapolis, MN.
4. Rodriguez EK, Weaver M, Herder L, Morgan J, Zurakowski D, Appleton P, Vrahas MS. Why are
Reported Nonunion Rates after Locked Plate Fixation of Distal Femur Fractures so Variable? A
Multicenter Retrospective Study of 284 Fractures. Paper Presentation – Orthopaedic Trauma Association
Annual Meeting; 2012 Oct 3-6; Minneapolis, MN.