CSIR-UGC National Eligibility Test (NET) · Medium: English & Hindi both Entire question paper is...

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Website: www.csirsquare.com ; Email: [email protected] ; Contact: 0731-4988-988 / 9111-266-238 CSIR SQUARE “Science is our Speciality & Speciality is our Identity” PROUDLY ANNOUNCES CLASSROOM COURSES FOR PREPARATIONS OF… CSIR-UGC National Eligibility Test (NET) for award of Junior Research Fellowship (JRF) & Lecturership (LS) in Life Science CSIR-UGC NET Examination Pattern : NET Exam for Science stream is conducted by CSIR twice a year in June & December It’s a Single OFFLINE Paper Based MCQ Test Duration: Hours Medium: English & Hindi both Entire question paper is divided into three sections: A, B and C. Sections Pattern of MCQ Total MCQs Max. limit of Answerable MCQs Marking Pattern Negative Marking (@ 25% for each wrong answer) Total Marks Allocated (30 + 70 + 100 = 200) A MCQs based on General Science, Quantitative Reasoning & Analysis and Research Aptitude 20 any 15 mark each 30 B Syllabus-related Conventional (simple) MCQs 50 any 35 mark each 70 C Analytical MCQs testing candidate's knowledge of scientific concepts and/or application of the scientific concepts 75 any 25 mark each 100 Website: www.csirhrdg.res.in

Transcript of CSIR-UGC National Eligibility Test (NET) · Medium: English & Hindi both Entire question paper is...

Page 1: CSIR-UGC National Eligibility Test (NET) · Medium: English & Hindi both Entire question paper is divided into three sections: A, B and C. Sections Pattern of MCQ Total MCQs Max.

Website: www.csirsquare.com; Email: [email protected]; Contact: 0731-4988-988 / 9111-266-238

CSIR SQUARE

“Science is our Speciality & Speciality is our Identity”

PROUDLY ANNOUNCES CLASSROOM COURSES FOR

PREPARATIONS OF…

CSIR-UGC National Eligibility Test (NET)

for award of Junior Research Fellowship (JRF) & Lecturership (LS)

in Life Science

CSIR-UGC NET Examination Pattern:

NET Exam for Science stream is conducted by CSIR twice a year in June & December

It’s a Single OFFLINE Paper Based MCQ Test

Duration: Hours

Medium: English & Hindi both

Entire question paper is divided into three sections: A, B and C.

Sections

Pattern of MCQ Total

MCQs

Max. limit of

Answerable

MCQs

Marking

Pattern

Negative

Marking (@ 25% for each

wrong answer)

Total Marks

Allocated (30 + 70 + 100 = 200)

A

MCQs based on General

Science, Quantitative

Reasoning & Analysis

and Research Aptitude

20 any 15 mark

each 30

B

Syllabus-related

Conventional (simple)

MCQs

50 any 35 mark

each 70

C

Analytical MCQs testing

candidate's knowledge of

scientific concepts

and/or application of the

scientific concepts

75 any 25 mark

each 100

Website: www.csirhrdg.res.in

Page 2: CSIR-UGC National Eligibility Test (NET) · Medium: English & Hindi both Entire question paper is divided into three sections: A, B and C. Sections Pattern of MCQ Total MCQs Max.

Website: www.csirsquare.com; Email: [email protected]; Contact: 0731-4988-988 / 9111-266-238

What do we provide here at CSIR SQUARE …???

Result-oriented complete exam preparation.

Extensive subject-wise teaching by Experts.

Lectures will be delivered in bilingual (English + Hindi).

Course duration of months / year.

Separate Morning (711) & Evening (48) batches available.

Regular classes Each & Every week.

Intensive & Interactive weekend classes.

Completely updated smart study material on Each & Every topic.

Test series consisting of Topic-wise Minor test & Major tests.

Special classes for Part-A questions on alternate Sundays.

Regular Feedbacks & Test-analysis sessions along with doubt clearance.

Free enrollment to Online platforms: Test, Doubt-clearance & Updates.

Starting Smart Classrooms for Animated AV lectures.

CSIR-UGC NET Classroom Course Fee Structure:

Course Six Month Classroom Program

(SMCP)

One Year Classroom Program

(OYCP)

Admission Mode Direct Admission Direct Admission

Medium Bilingual Bilingual

Commencement of Classes 5th

& 15th

Jan / 5th

& 15th

July 5th

& 15th

Jan / 5th

& 15th

July

Registration Fee 500/- 1000/-

Course

Fee

(CF)

along with Last

Date of Fee

Deposition

Lump-sum (within 1 week of admission)

25000/-

[ Tuition fee = 21186/- +

GST@18% = 3814/- ]

35000/-

[ Tuition fee = 29660/- +

GST@18% = 5340/- ]

1st Installment

(within 1 week of admission) 11000/- (including GST@18%) 16000/- (including GST@18%)

2nd

Installment (within 1 month of admission)

10000/- (including GST@18%) 10000/- (including GST@18%)

3rd

Installment (within 3 months of admission)

5000/- (including GST@18%) 5000/- (including GST@18%)

Note:

1). For total course fee paid in Lump-sum: Rebate of 1000/- will be given.

2). All forms of course fee are Non-refundable.

3). GST on all forms of fee will be charged as per current rate i.e. @ 18%.

4). For fee payment in Installments “Post Dated Cheques” have to be submitted at the time of Admission.

“Overall, we are committed to provide best quality content

& guidance to our students to achieve their target”

Page 3: CSIR-UGC National Eligibility Test (NET) · Medium: English & Hindi both Entire question paper is divided into three sections: A, B and C. Sections Pattern of MCQ Total MCQs Max.

Website: www.csirsquare.com; Email: [email protected]; Contact: 0731-4988-988 / 9111-266-238

Life Science CSIR-UGC NET Class Schedule:

Date Day Morning Batch Time Evening Batch Time Topics

- Sunday

10.00 am - 12.00 pm

Date, Lecturer & Topic

of each & every class

will be regularly mentioned over the

Notice board on Sundays

(Also refer the Notice board for Timing

updates & Schedule of Extra Classes)

12.00 pm - 3.00 pm: Minor / Major Test

3.00 pm - 5.00 pm

- Monday Holiday

- Tuesday 7.00 am - 11.00 pm 4.00 pm - 8.00 pm

- Wednesday 7.00 am - 11.00 pm 4.00 pm - 8.00 pm

- Thursday 7.00 am - 11.00 pm 4.00 pm - 8.00 pm

- Friday 7.00 am - 11.00 pm 4.00 pm - 8.00 pm

- Saturday 7.00 am - 11.00 pm 4.00 pm - 8.00 pm

CSIR-UGC NET Life Science Analysis Chart

GENERAL APTITUDE TOPICS Average no. of Questions in…

Part-A

1. General Aptitude (esp. Time-Work, Time-Distance, Percentage) 5 – 6

2. Graphical Representation & Analysis 3 – 4

3. Mensuration 2 – 3

4. Series Completion 2 – 3

LIFE SCIENCE TOPICS Average no. of Questions in…

Part-B Part-C

1. Molecules and their Interaction Relevant to Biology 2 – 3 3 – 4

2. Cellular Organization 3 – 4 4 – 5

3. Fundamental Processes 2 – 3 3 – 4

4. Cell Communication and Cell Signaling 4 – 5 6 – 7

5. Developmental Biology 3 – 4 5 – 6

6. System Physiology – Plant 4 – 5 5 – 6

7. System Physiology – Animal 3 – 4 5 – 6

8. Inheritance Biology 3 – 4 6 – 7

9. Diversity of Life Forms 3 – 4 5 – 6

10. Ecological Principles 4 – 5 6 – 7

11. Evolution and Behavior 3 – 4 4 – 5

12. Applied Biology 2 – 3 3 – 4

13. Methods in Biology 4 – 5 7 – 8

Page 4: CSIR-UGC National Eligibility Test (NET) · Medium: English & Hindi both Entire question paper is divided into three sections: A, B and C. Sections Pattern of MCQ Total MCQs Max.

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CSIR-UGC NET Life Science Syllabus

1). BIOCHEMISTRY - MOLECULES & THEIR INTERACTION

RELEVANT TO BIOLOGY / अणुओ ंतथा उनकी परस्पर क्रिया 1 Structure of Atoms, Molecules & Chemical bonds.

2 Composition, Structure & Functions of Biomolecules [Carbohydrate, Lipids, Protein, Nucleic acids & Vitamins]

3 Stabilizing Interactions [Vander Waals, Electrostatic, H-bonding, Hydrophobic interaction, etc]

4 Principles of Biophysical-chemistry [pH, Buffer, Rxn kinetics, Thermodynamics, Colligative properties]

5 Bioenergetics, Glycolysis, Oxidative phosphorylation, Coupled rxn, Group transfer, Biological Energy

Transducers

6 Principles of catalysis, enzymes & enzyme kinetics, Enzyme regulation, Mech. of Enzyme catalysis,

Isoenzymes

7 Conformation of Proteins [Ramchandran plot, Sec. structure, Domains, Motif & Folds]

8 Conformation of Nucleic acids [Helix (A, B, C), t-RNA, micro-RNA]

9 Stability of Proteins & Nucleic acids

10 Metabolism of Carbohydrates, Lipids, Amino acids, Nucleotides & Vitamins

2). CELLULAR ORGANIZATION / कोशिकीय संगठन

1 Membrane

Structure &

Function:

Structure of Model membrane, Lipid bilayer and Membrane protein

Diffusion, Osmosis, Ion channels, Active transport & Membrane pumps

Mechanism of sorting and regulation of intracellular transport

Electrical properties of membranes

2 Structural

Organization &

Function of

Intracellular

Organelles:

Cell wall

Nucleus

Endoplasmic reticulum, Golgi bodies, Lysosomes & Vacuoles

Peroxisomes

Mitochondria

Plastids & Chloroplast

Structure & function of Cytoskeleton and its role in Motility

3 Organization of

Genes &

Chromosomes:

Operon

Unique & Repetitive DNA

Transposons

Interrupted genes, gene families

Structure of Chromatin and Chromosomes

Heterochromatin & Euchromatin

4 Cell Division & Cell

Cycle:

Mitosis and meiosis, their Regulation

Steps in cell cycle

Regulation and control of Cell cycle

5 Microbial

Physiology:

Growth yield and Characteristics

Strategies of Cell division

Stress response

3). FUNDAMENTAL PROCESSES / मूलभूत विधियााँ 1 DNA Replication,

Repair and

Recombination:

Unit of replication & Enzymes involved

Replication origin and Replication fork

Fidelity of replication

Extra-chromosomal replicons

DNA damage and repair mechanisms

Homologous and site-specific recombination

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Website: www.csirsquare.com; Email: [email protected]; Contact: 0731-4988-988 / 9111-266-238

2 RNA Synthesis and

Processing:

Transcription Factors and Machinery

Formation of Initiation complex, Transcription activator and repressor

RNA polymerases

Capping, Elongation & Termination

RNA processing, RNA editing, RNA splicing & Poly-adenylation

Structure and function of different types of RNA, RNA transport

3 Protein Synthesis

and Processing:

Ribosome

Formation of Initiation complex, Initiation factors and their regulation

Elongation and elongation factors & Termination,

Genetic code

Amino-acylation of tRNA, tRNA-identity & Aminoacyl tRNA synthetase

Translational proof-reading & Translational inhibitors

Post- translational modification of proteins

4 Control of Gene

Expression at

Transcription &

Translation Level:

Regulating the expression of Phages, Viruses, Prokaryotic and Eukaryotic genes

Role of chromatin in Gene expression and Gene silencing

4). CELL COMMUNICATION & CELL SIGNALING / कोशिका संचारण तथा कोशिका संकेतन

1 Host-Parasite

Interaction:

Recognition and Entry processes of different pathogens like bacteria, viruses into

animal and plant host cells; Alteration of host cell behavior by pathogens

Virus-induced cell transformation

Pathogen-induced diseases in Animals and Plants

Cell-Cell fusion in both Normal and Abnormal cells

2 Cell Signaling: Hormones and their receptors

Cell surface receptor & Signaling through G-protein coupled receptors

Signal transduction pathways, Second messengers& Regulation of signaling

pathway

Bacterial and Plant two-component systems,

Light signaling in plants, Bacterial chemotaxis and Quorum sensing

3 Cellular

Communication:

Regulation of Hematopoiesis

General principles of Cell Communication

Cell adhesion and Roles of different adhesion molecules

Gap junctions, Extracellular matrix & Integrins

Neurotransmission and its regulation

4 Cancer: Genetic rearrangements in Progenitor cells, Oncogenes & Tumor suppressor genes

Cancer and the cell cycle

Virus-induced cancer

Metastasis, Interaction of cancer cells with normal cells

Apoptosis

Therapeutic interventions of Uncontrolled Cell Growth

5 Innate & Adaptive

Immune System:

Cells and molecules involved in Innate and Adaptive immunity

Antigens, Antigenicity and Immunogenicity

B and T cell epitopes

Structure and function of antibody molecules, Generation of antibody diversity,

Monoclonal antibodies & Antibody engineering

Antigen-antibody interactions

MHC molecules; Antigen processing and presentation

Activation and Differentiation of B and T cells

B and T cell receptors

Humoral and Cell- mediated immune responses

Primary and secondary immune modulation

Complement system

Toll-like receptors, Cell-mediated effector functions

Inflammation, Hypersensitivity and Autoimmunity

Immune response during Bacterial (tuberculosis), Parasitic (malaria) and Viral

(HIV) infections

Congenital and Acquired Immunodeficiencies; Vaccines

Page 6: CSIR-UGC National Eligibility Test (NET) · Medium: English & Hindi both Entire question paper is divided into three sections: A, B and C. Sections Pattern of MCQ Total MCQs Max.

Website: www.csirsquare.com; Email: [email protected]; Contact: 0731-4988-988 / 9111-266-238

5). DEVELOPMENTAL BIOLOGY / पररििधनीय जैविकी 1 Basic Concepts of

Development:

Potency, Commitment, Specification, Induction, Competence, Determination &

Differentiation

Morphogenetic gradients

Cell fate and Cell lineages

Stem cells

Genomic equivalence and the cytoplasmic determinants

Imprinting; Mutants and Transgenics in analysis of development

2 Gametogenesis,

Fertilization & Early

Development:

Production of gametes

Cell surface molecules in sperm-egg recognition in animals

Embryo sac development and double fertilization in plants

Zygote formation, cleavage, blastula formation, embryonic fields, gastrulation and

formation of germ layers in animals

Embryogenesis, Establishment of symmetry in plant

Seed formation and germination

3 Morphogenesis &

Organogenesis in

Animals:

Cell aggregation and differentiation in Dictyostelium

Axes and pattern formation in Drosophila, Amphibia and Chick

Organogenesis – Vulva formation in Caenorhabditis elegans, Eye lens induction,

Limb development and Regeneration in vertebrates

Differentiation of neurons

Post embryonic development - Larval formation and Metamorphosis

Environmental regulation of normal development

Sex determination

4 Morphogenesis &

Organogenesis in

Plants:

Organization of shoot and root apical meristem

Shoot and Root development

Leaf development and Phyllotaxy

Transition to flowering, Floral meristems and Floral development in Arabidopsis

and Antirrhinum

5 Programmed Cell Death, Aging & Senescence

6). PLANT PHYSIOLOGY

1 Photosynthesis:

Light Harvesting Complexes

Mechanisms of Electron transport

Photo-protective mechanisms

CO2 fixation - C3, C4 & CAM pathways

2 Respiration &

Photorespiration:

Citric acid cycle

Plant mitochondrial electron transport and ATP synthesis

Alternate oxidase & Photo-respiratory pathway

3 Nitrogen

Metabolism:

Nitrate and Ammonium assimilation

Amino acid biosynthesis

4 Plant Hormones: Biosynthesis, Storage, Breakdown & Transport

Physiological effects and mechanisms of action

5 Sensory

Photobiology:

Structure, function and mechanisms of action of Phytochromes, Cryptochromes

and Phototropins

Stomatal movement

Photoperiodism and biological clocks

6 Solute Transport &

Photo-assimilate

Translocation:

Uptake, transport and translocation of water, ions, solutes and macromolecules

from soil, through cells, across membranes, through Xylem and Phloem

Transpiration

Mechanisms of loading and unloading of Photoassimilates

7 Secondary

Metabolites: Biosynthesis of Terpenes, Phenols and Nitrogenous compounds and their roles

8 Stress Physiology: Responses of plants to Biotic (pathogen and insects) stresses

Responses of plants to Abiotic (water, temperature and salt) stresses

Page 7: CSIR-UGC National Eligibility Test (NET) · Medium: English & Hindi both Entire question paper is divided into three sections: A, B and C. Sections Pattern of MCQ Total MCQs Max.

Website: www.csirsquare.com; Email: [email protected]; Contact: 0731-4988-988 / 9111-266-238

7). ANIMAL PHYSIOLOGY 1 Blood & Circulation: Blood corpuscles, Haemopoiesis and formed elements

Plasma function, blood volume, blood volume regulation

Blood groups & Haemoglobin

Immunity & Haemostasis

2 Cardiovascular

System:

Comparative anatomy of Heart structure

Myogenic heart & Specialized tissue

ECG – its principle and significance

Cardiac cycle, Heart as a pump & Blood pressure

Neural and Chemical regulation of all above

3 Respiratory System: Comparison of respiration in Different species

Anatomical considerations

Transport of gases, Exchange of gases & Waste elimination

Neural and Chemical regulation of respiration

4 Nervous System: Neurons

Action potential

Gross Neuro-anatomy of Brain and Spinal cord

Central and Peripheral nervous system,

Neural control of muscle tone and posture

5 Sense Organs: Vision, Hearing and Tactile response

6 Excretory System: Comparative physiology of excretion; Kidney

Urine formation, Urine concentration, Waste elimination & Micturition

Regulation of Water balance, Blood volume & Blood pressure

Regulation of electrolyte balance & acid-base balance

7 Thermoregulation: Comfort zone

Body temperature – physical, chemical & neural regulation

Acclimatization

8 Stress & Adaptation:

9 Digestive System: Digestion & Absorption

Energy balance & BMR

10 Endocrinology &

Reproduction:

Endocrine glands

Basic mechanism of hormone action, hormones and diseases

Reproductive processes, Gametogenesis & Ovulation

Neuro-endocrine regulation of Reproduction

8). INHERITANCE BIOLOGY / िंिागतत जीि विज्ञान

1 Mendelian

Principles मेण्डल के

शसध्दान्त

Dominance / प्रभाविता Segregation / विसयंोजन

Independent assortment / स्िततं्र अपव्यहून

Deviation from Mendelian Inheritance / मेण्डल ििंागतत से विचलन

2 Concept of Gene

जीन की िारणा Allele / यगु्म विकल्पी Multiple alleles / बहुयगु्म विकल्पी Pseudo allele / कूटयगु्म विकल्पी Complementation tests / सम्परूण परीक्षण

3 Extensions of

Mendelian

Principles

मेण्डल के शसध्दान्तो का विस्तार

Codominance / सह-प्रभाविता Incomplete Dominance / अपणूध प्रभाविता Gene Interactions /

Pleiotropy /

Genomic Imprinting /

Penetrance & Expressivity /

Phenocopy /

Linkage & Crossing over /

Sex linkage /

Sex-Limited & Sex-Influenced Characters / सेक्स शलशमटेड तथा सेक्स इन््लुएन्स

केरेक्टसध

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4 Gene Mapping

Methods

जीन मानधचत्रण

विधियााँ

Linkage Maps / सहलग्नता मानधचत्र

Tetrad Analysis / टे्रट्राड एनाशलशसस

Mapping with Molecular Markers / आण्ण्िक मारकर से मानधचत्रण

Mapping by using Somatic Cell Hybrids / दैहहक कोिा सकंर से मानधचत्रण

Development of Mapping Population in Plants

5 Extra Chromosomal

Inheritance:

अततररक्त गुणसूत्रीय

िंिागतत

Inheritance of Mitochondrial & Chloroplast Genes / माइटोकांड्रियल तथा क्लोरोप्लास्ट जीनस की ििंागतत

Maternal Inheritance / मातकृ ििंागतत

6 Microbial Genetics

सूक्ष्मजैविक आनुिंशिकी Methods of genetic transfers – transformation, conjugation, transduction and

sexduction

Mapping genes by Interrupted Mating

Fine Structure Analysis of Genes / जीन का सूक्ष्म संरचनीय विश्लेषण

7 Human Genetics

मानि आनुिंशिकी Pedigree analysis / िंिािली विश्लेषण

Lod score for linkage testing / लोड स्कोर

Karyotypes

Genetic disorders

8 Quantitative

Genetics

मात्रात्मक आनुिंशिकी

Polygenic inheritance / बहुजीन ििंागतत

Heritability & Its Measurements / ििंागततका का मापन

QTL mapping / क्य.ूटी.एल. मानधचत्रण

9 Mutation

उत्पररितधन

Types, causes and detection

Mutant types – lethal, conditional, biochemical, loss of function, gain of function

Germinal verses somatic mutants

Insertional mutagenesis

10 Structural &

Numerical

Alterations of

Chromosomes

गुणसूत्रों की संरचना तथा संख्यात्मक पररितधन

Deletion / विलोपन

Duplication / गुणन

Inversion / पलटना Translocation / स्थानान्तरण

Ploidy & their Genetic Implications / प्लाइडी तथा उनका जेनेहटक

11 Recombination

पुनःसंयोजन

Homologous & Non-homologous recombination (समजात तथा असमजात पुनःसंयोजन)

including transposition

9). DIVERSITY OF LIFE FORMS / जीिन के रूपों में विवििता 1 Principles & Methods

of Taxonomy:

Concepts of species and Hierarchical Taxa

Biological nomenclature

Classical & Quantititative methods of taxonomy of Plants, Animals & Microbes

2 Levels of Structural

Organization:

Unicellular, Colonial and Multicellular forms

Levels of organization of Tissues, Organs & Organ-systems

Comparative anatomy

Adaptive radiation & Adaptive modifications

3 Outline Classification

of Plants, Animals &

Microorganisms:

Important criteria used for Classification in each Taxon

Classification of Plants, Animals and Microorganisms

Evolutionary relationships among Taxa

4 Natural History of

Indian Subcontinent:

Major habitat types of the Subcontinent

Geographic origins and Migrations of species

Common Indian mammals & birds

Seasonality and Phenology of the subcontinent

5 Organisms of Health

& Agricultural

Importance:

Common parasites and pathogens of Humans

Domestic Animals and Crops

6 Organisms of

Conservation

Concern:

Rare species

Endangered species

Conservation strategies

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Website: www.csirsquare.com; Email: [email protected]; Contact: 0731-4988-988 / 9111-266-238

10). ECOLOGICAL PRINCIPLES / पररण्स्थततकी के शसध्दान्त

1 The Environment: Physical environment

Biotic environment

Biotic and Abiotic interactions

2 Habitat & Niche: Concept of habitat and niche

Niche width and overlap

Fundamental and Realized niche

Resource partitioning

Character displacement

3 Population Ecology: Characteristics of a population

Population growth curves

Population regulation

Life history strategies (r and K selection)

Concept of Metapopulation – demes and dispersal, interdemic extinctions, age

structured populations

4 Species Interactions: Types of interactions

Interspecific competition

Herbivory & Carnivory

Pollination

Symbiosis

5 Community

Ecology:

Nature of communities

Community structure and attributes

Levels of species diversity and its measurement

Edges and Ecotones

6 Ecological

Succession:

Types of Succession

Mechanisms & Changes involved in succession

Concept of climax

7 Ecosystem Ecology: Ecosystem structure & Ecosystem function

Energy flow and Mineral cycling (C,N,P);

Primary Production and Decomposition

Structure and function of some Indian ecosystems: Terrestrial (forest, grassland)

and Aquatic (fresh water, marine, estuarine)

8 Biogeography: Major Terrestrial Biomes

Theory of Island biogeography

Biogeographical zones of India

9 Applied Ecology: Environmental pollution

Global environmental change

Biodiversity: Status, Monitoring & Documentation

Major drivers of Biodiversity Change

Biodiversity Management Approaches

10 Conservation

Biology:

Principles of Conservation

Major approaches to Management

Indian case studies on Conservation / Management strategy (Project Tiger,

Biosphere reserves)

11). EVOLUTION & BEHAVIOUR / विकास एि ंव्यिहार

1 Emergence of

Evolutionary

Thoughts:

Lamarckism

Darwinism–concepts of variation, adaptation, struggle, fitness & natural selection

Mendelism

Spontaneity of mutations

The Evolutionary synthesis

2 Origin of Cells &

Unicellular

Evolution:

Origin of basic biological molecules

Abiotic synthesis of organic monomers and polymers

Concept of Oparin and Haldane

Experiment of Miller (1953)

The first cell; Evolution of prokaryotes; Origin of eukaryotic cells; Evolution of

unicellular eukaryotes

Anaerobic metabolism, Photosynthesis and Aerobic metabolism

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Website: www.csirsquare.com; Email: [email protected]; Contact: 0731-4988-988 / 9111-266-238

3 Paleontology &

Evolutionary

History:

Evolutionary Time Scale - Eras, Periods and Epoch

Major events in the evolutionary time scale

Origins of unicellular and multi cellular organisms

Major groups of plants and animals

Stages in primate evolution including Homo

4 Molecular Evolution: Concepts of Neutral evolution, Molecular divergence and Molecular clocks

Molecular tools in Phylogeny, Classification and Identification

Protein and Nucleotide sequence analysis

Origin of New genes and Proteins

Gene duplication and divergence

5 The Mechanisms: Population genetics – Populations, Gene pool, Gene frequency

Hardy-Weinberg Law

Concepts and rate of change in gene frequency through natural selection, migration

and random genetic drift

Adaptive radiation & Isolating mechanisms

Speciation: Allopatricity and Sympatricity

Convergent evolution

Sexual selection

Co-evolution

6 Brain, Behavior &

Evolution: Approaches and Methods in study of Behavior

Proximate and Ultimate causation

Altruism and Evolution - Group selection, Kin selection, Reciprocal altruism

Neural basis of learning, memory, cognition, sleep & arousal

Biological clocks

Development of behavior

Social communication & Social dominance

Use of Space and Territoriality

Mating systems, Parental investment and Reproductive success

Parental care

Aggressive behavior

Habitat selection and Optimality in foraging

Migration, Orientation & Navigation

Domestication & Behavioral changes

12). APPLIED BIOLOGY / व्यिहाररक जीि विज्ञान

1 Microbial fermentation and production of small and macro molecules

2 Application of immunological principles, vaccines, diagnostics.

3 Tissue and cell culture methods for plants and animals

4 Transgenic animals and plants, molecular approaches to diagnosis and strain identification

5 Genomics and its application to health and agriculture, including gene therapy

6 Bio-resource & Uses of Biodiversity

7 Breeding in plants and animals, including marker – assisted selection

8 Bioremediation & Phyto-remediation

9 Biosensors

13). METHODS IN BIOLOGY / जीि विज्ञान में पविधियााँ 1 Molecular Biology &

Recombinant DNA

Methods:

Isolation and Purification of RNA, DNA (genomic and plasmid) & Proteins,

different separation methods

Analysis of RNA, DNA and proteins by one and two dimensional gel

electrophoresis; Isoelectric focusing gels

Molecular cloning of DNA or RNA fragments in bacterial and eukaryotic systems

Expression of recombinant proteins using bacterial, animal and plant vectors

Page 11: CSIR-UGC National Eligibility Test (NET) · Medium: English & Hindi both Entire question paper is divided into three sections: A, B and C. Sections Pattern of MCQ Total MCQs Max.

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Isolation of specific nucleic acid sequences

Generation of Genomic and cDNA libraries in Plasmid, Phage, Cosmid, BAC &

YAC vectors

In-vitro mutagenesis and deletion techniques, gene knock out in bacterial and

eukaryotic organisms

Protein sequencing methods, detection of post translation modification of proteins.

DNA sequencing methods, strategies for genome sequencing

Methods for analysis of gene expression at RNA and protein level, large scale

expression, such as micro array based techniques

Isolation, separation and analysis of carbohydrate and lipid molecules RFLP,

RAPD & AFLP techniques

2 Histo-chemical &

Immuno-techniques: Antibody generation

Detection of molecules using ELISA, RIA, Western blot, Immuno-precipitation,

Flow-cytometry and Immuno-fluorescence microscopy

Detection of molecules in living cells

In-situ localization by techniques such as FISH and GISH

3 Biophysical Method: Molecular analysis using UV/visible, fluorescence, circular dichroism, NMR and

ESR spectroscopy

Molecular structure determination using X-ray diffraction and NMR

Molecular analysis using Light Scattering

Different types of Mass Spectrometry and Surface Plasma Resonance methods

4 Statistical Methods: Measures of Central tendency and Dispersal

Probability distributions (Binomial, Poisson and Normal)

Sampling distribution

Difference between parametric and non-parametric statistics

Confidence Interval

Errors

Levels of significance;

Regression and Correlation

t-Test

Analysis of variance

X2 Test

Basic introduction to Muetrovariate Statistics

5 Radio-labeling

techniques:

Detection and Measurement of different types of Radioisotopes used in biology

Incorporation of radioisotopes in Biological tissues and cells

Molecular imaging of Radioactive material

Safety guidelines

6 Microscopic

techniques:

Visualization of cells and subcellular components by Light Microscopy

Resolving powers of different Microscopes

Microscopy of living cells

Scanning and Transmission microscopes

Different fixation and staining techniques for EM, freeze-etch and freeze- fracture

methods for EM

Image processing methods in Microscopy

7 Electrophysiological

methods:

Single neuron recording

Patch-clamp recording

ECG

Brain Activity Recording

Lesion and stimulation of Brain

Pharmacological Testing

PET, MRI, fMRI & CAT

8 Methods in field

biology:

Methods of estimating population density of Animals & Plants

Ranging patterns through Direct, Indirect & Remote observations

Sampling methods in the study of Behavior

Habitat characterization: ground and remote sensing methods

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Csir Square’s Test Schedule for

CSIR-UGC NET Life Science Dec – 2018

[ Same schedule for both Classroom courses & Distance Learning courses ]

Test Type Date Topics Covered

Minor Test # 01 15th

July Molecules and their Interaction & Fundamental Processes

Minor Test # 02 29th

July Molecules and their Interaction & Fundamental Processes

Minor Test # 03 12th

Aug Cellular Organization & Inheritance Biology

Minor Test # 04 26th

Aug Cellular Organization & Inheritance Biology

st

Major Test

(Semi-major type) 2

nd Sep

Molecules and their Interaction

Cellular Organization

Fundamental Processes

Inheritance Biology

Diversity of Life Forms

Minor Test # 05 9th

Sep Animal Physiology & Cell Communication and Cell Signaling

Minor Test # 06 23rd

Sep Animal Physiology & Cell Communication and Cell Signaling

Minor Test # 07 7th

Oct Animal Physiology & Plant Physiology

Minor Test # 08 21st Oct Applied Biology & Plant Physiology

nd

Major Test

(Semi-major type) 28

th Oct

Animal Physiology

Cell Communication and Cell Signaling

Plant Physiology

Applied Biology

Ecological Principles

Minor Test # 09 4th

Nov Methods in Biology, Developmental Biology & Evolution and Behaviour

Minor Test # 10 18th

Nov Methods in Biology, Developmental Biology & Evolution and Behaviour

Minor Test # 11 30th

Nov General Aptitude

rd

Major Test 1st Dec All topics covered as per CSIR-UGC NET Examination

th

Major Test 3rd

Dec All topics covered as per CSIR-UGC NET Examination

th

Major Test 5th

Dec All topics covered as per CSIR-UGC NET Examination

CSIR-UGC NET 16th

Dec “Best of Luck”

Highlights:

Total Minor & Major tests will cover the whole syllabus.

Minor Test consists of Questions (Part A: 15, Part B: 35 & Part C: 25) with a time duration of Hours.

Major Test consists of Questions (Part A: 20, Part B: 50 & Part C: 75) with a time duration of Hours.

All Minor / Major test will commence sharply at on specified date.

Special Minor test will be conducted for General Aptitude (consisting of Part A: 100 questions).

Minor test are weekly topic-wise test needed to cover high point gray areas.

All Questions will be based on current examination trend.

Solutions are provided with explanation and valid reference.

Topic based analysis and suggestion will be provided to students intended to improve their preparation.

“ Science iS our Specialty & Specialty iS our identity ”