Crossmatch Inkompatibel - RSUP Dr Sardjito...•Golongan darah donor berbeda dengan pasien...
Transcript of Crossmatch Inkompatibel - RSUP Dr Sardjito...•Golongan darah donor berbeda dengan pasien...
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TEGUH TRIYONODept. of Clinical Pathology
Faculty of Medicine, Universitas Gadjah MadaRSUP Dr. Sardjito
Yogyakarta
Crossmatch InkompatibelArti & Konsekuensi
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• Penggolongan darah
• Skrining antibodi
• Crossmatch
Pra-Transfusi
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Apa itu crossmatch?
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1. Immediate Spin Crossmatch
2. Anti globulin Crossmatch
3. Electronic Crossmatch
Crossmatch
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Metode
o Tube test
o Collumn Agglutination Test
o Microplate
o Solid Phase Red Cell Agglutination
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MAYOR MINOR AUTOKONTROL
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AGLUTINASI
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KOMPATIBEL INKOMPATIBEL
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Penyebab inkompatibel
Faktor lain?
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• Golongan darah donor berbeda dengan pasien
• Antibodi subgrup: misal Anti-A1
• Anti-A or anti-B dari ibu
• Rouleaux formation
• DCT donor positif
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• Anti CD38 dalam serum
• Antibody of undetermined specificity
• Contamination
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Transfusi darah inkompatibel
Konsekuensi?
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Transfusi pasien A RhD pos dengandonor WB O Rh pos
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Intravascular haemolysis of 51Cr-labelled ABO-incompatible red cells
1: Sel B diinjeksikan kepada pasien A2: Sel A2 diinjeksikan kepada pasien O
1
1
2
2
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Gol darahpasien
MAJOR MINOR AC
O Neg 1+ 1+
Contoh kasus: Crossmatch dengandonor O RhD pos
Dilakukan crossmatch dengan 10 donor O RhDpos: hasil SAMA
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4-7 Februari 2020 di Hotel Tentrempendaftaran:
http://bit.ly/bact2020
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4-7 Februari 2020 di Hotel Tentrempendaftaran:
http://bit.ly/bact2020
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