7/31/2019 Creatine Paper

1/10

Jl{bya{ryb Ybplbv? Hmpbj @mycw m` Gyba{lhb4 Ayb [nb| Wrubylmy {m Cmhmn|kya{b=

Ibh Bwfym* I(W(* GWGW* GLWWH

Gyba{lhb .cb{n|jfrahlklhb#agb{lg aglk, lw mhb m` {nb cmw{ b~{bhwlpbj| w{rklbk klb{ay| wruujbcbh{w

apaljaijb {mka|( L{ lw a ha{ryajj| mggryylhf hl{ymfbhmrw gmcumrhk w|h{nbwlzbk `ymc {nb aclhm aglkw

Fj|glhb* Ayflhlhb* ahk Cb{nlmhlhb ahk lw uybwbh{ lh ybja{lpbj| jayfb qrah{l{lbw lh cmw{ ahlcaj `jbwnbw wrgn

aw `lwn ahk ybk cba{( Lh nrcahw* {nb caomyl{| .x

7/31/2019 Creatine Paper

2/10

ilmapaljailjl{|* ijma{lhf-cajaiwmyu{lpb w|cu{mcw* jagd m` ybwumhwb {m wruujbcbh{a{lmh* ahk ummy aqrbmrw

wmjriljl{|( [m akkybww {nbwb ahk m{nby lwwrbw* wruujbcbh{ gmcuahlbw napb gyba{bk aj{byha{lpb payla{lmhw

m` gyba{lhb {na{ gah ib wbuaya{bk lh{m wl~ ga{bfmylbw? Gyba{lhb Waj{w .gyba{lhb u|yrpa{b* gyba{lhb

n|kymgnjmylkb* kl# my {yl# gyba{lhb caja{b* gyba{lhb fjrgmha{b* gyba{lhb hl{ya{b* gyba{lhb mym{a{b* um{awwlrc

gyba{lhb gnbja{b* wmklrc gyba{lhb gnbja{b* ahk cafhbwlrc gyba{lhb gnbja{b,* Ir``bybk Gyba{lhb .Dyb#

Ajdaj|h,* Umj|b{n|jbhb Fj|gmw|ja{bk Gyba{lhb .UBF,* Gyba{lhb Bw{byw .gyba{lhb b{n|j bw{by,* ahk Gyba{lhb

Ajgmnmjw .gyba{lhmj#M#unmwuna{b,( Bagn m` {nbwb payla{lmhw napb {nbly mvh rhlqrb gnbclgaj uymuby{lbw

{na{ ayb uryumy{bk {m lcuympb {nb ilmjmflgaj ag{lpl{| m` {nb gmcumrhk( Cmyb lcumy{ah{j|* jl{{jb wglbh{l`lg

bpajra{lmh m` {nbwb aj{byha{lpb `mycw auubay {m ib uybwbh{* jbaplhf a{njb{bw ahk gmhwrcbyw rhgby{alh

aimr{ vnlgn jbakw {m {nb fyba{bw{ lhgybawbw lh uby`mycahgb ahk vnlgn lw {nb cmw{ vbjj {mjbya{bk `myc(

[nb uryumwb m` {nlw ybplbv vaw {m ahaj|zb {nb jl{bya{ryb mh hmpbj `mycw m` gyba{lhb ahk kb{byclhb l` {nb

bplkbhgb gryybh{j| apaljaijb yb`r{bw my wruumy{w {nb rwb m` aj{byha{lpb `mycw m` gyba{lhb aw gmcuaybk {m

{nb cmw{ gmccmhj| gmhwrcbk ahk w{rklbk `myc4 gyba{lhb cmhmn|kya{b(

Aw bhgmcuawwlhf ajj m` {nb apaljaijb jl{bya{ryb mh gyba{lhb cmhmn|kya{b l{wbj` gmrjk wuah a

{b~{immd l{wbj`* mhj| {nb cmw{ uby{lhbh{ ahk gmcuybnbhwlpb w{rklbw napb ibbh lhgjrkbk lh {nlw ybplbv.calhj| w{rklbw uby{alhlhf {m gmccmh c|{nw aimr{ gyba{lhb* ahk cb{a ahaj|wbw,(

Wlhgb {nb `lyw{ w{rk| uby`mycbk lhpbw{lfa{lhf {nb ybja{lmhwnlu ib{vbbh gyba{lhb wruujbcbh{a{lmh

ahk b~byglwb uby`mycahgb ru {m {nb {ylajw m` {mka|* cmhmn|kya{b umvkby kmclha{bw {nb jl{bya{ryb( Lh ah

b~gbjjbh{ ybplbv m` {nb {ylajw {na{ napb ibbh gmcujb{bk* a jbaklhf ar{nmyl{| lh gyba{lhb ybwbaygn* Ky(

Ylgnayk Dyblkby* naw gmhgjrkbk* m` {nb auuym~lca{bj| 755 w{rklbw {na{ napb bpajra{bk {nb um{bh{laj

byfmfbhlg pajrb m` gyba{lhb wruujbcbh{a{lmh* aimr{ 65" m` {nbwb w{rklbw ybumy{ w{a{lw{lgajj| wlfhl`lgah{

ybwrj{w vnljb ybcalhlhf w{rklbw fbhbyajj| ybumy{ hmh#wlfhl`lgah{ falhw lh uby`mycahgb T0S( A 9557 cb{a

ahaj|wlw kmhb i| Iyahgn mh {nb b``bg{w m` gyba{lhb wruujbcbh{a{lmh lh ybfaykw {m imk| gmcumwl{lmh ahk

uby`mycahgb klwgmpbybk {na{ b``bg{ wlzb vaw wlfhl`lgah{j| fyba{by `my gnahfbw lh jbah imk| caww* aw vbjj

aw ruuby imk| ahk ybub{l{lpb imr{ jaimya{my| iawbk b~byglwb( [nlw ahaj|wlw ummjbk ;6 wriobg{w vbyb yahkmclzbk* ijlhkbk* ahk ujagbim gmh{ymjjbk T6S(Hrcbymrw wcajjby cb{a ahaj|wbw napb ibbh uby`mycbk vnlgn napb ajj gmcb {m {nb wacb gmhgjrwlmhw4

gyba{lhb lhfbw{lmh lcuympbw ca~lcaj b``my{* nlfn lh{bhwl{| wnmy{ krya{lmh b~byglwb lh nbaj{n| lhklplkrajw

ahk {nmwb vl{n crwgrjay k|w{ymunlbw T>#

7/31/2019 Creatine Paper

3/10

`mrhk {na{ 0 fyacw m` gyba{lhb-ka| wruujbcbh{bk `my 19 vbbdw jbk {m {nb wacb a`mybcbh{lmhbk ybwrj{w4

wlfhl`lgah{j| fyba{by {m{aj imk| ahk `a{ `ybb caww* 1 ybu ca~ w{ybhf{n* ahk c|m`liyljjay uym{blh gmh{bh{ lh

gmcuaylwmh {m gmh{ymjw T17S( [nbwb ybumy{w wruumy{ {nb hm{lmh {na{ gyba{lhb wruujbcbh{a{lmh hm{ mhj|

umwl{lpbj| lh`jrbhgbw wnmy{ {byc mr{gmcbw* ir{ ajwm jmhf {byc akau{a{lmhw {m b~byglwb( Cmyb lcumy{ah{j|* l{

kmbw wm vl{nmr{ {nb mggryybhgb m` wbylmrw akpbywb bpbh{w(

Ybfaykjbww m` {nb jagd m` ybumy{bk wlkb b``bg{w wlhgb {nb akpbh{ m` gyba{lhb rwb* {nb jmhf {bycwa`b{| ybcalhw a kbia{bk {mulg( M`{bh{lcbw {nmwb lh muumwl{lmh m` gyba{lhb wruujbcbh{a{lmh gl{b {nb

um{bh{laj hbfa{lpb b``bg{w rumh {nb dlkhb|w aw vbjj aw ah lhgybawbk ylwd m` kbn|kya{lmh ahk crwgjb

gyacuw( [m ka{b* {nbwb gmhgbyhw napb hm{ ibbh pajlka{bk lh {nb jl{bya{ryb* ahk {nb `bv ybumy{w {na{ napb

a{{bcu{bk {m cadb {nbwb awwmgla{lmhw napb jbk {m uybca{ryb ahk wbhwa{lmhajlzbk cbkla gmhgjrwlmhw( @my

b~acujb* a 1S(

Lh ybfaykw {m gyba{lhb ahk crwgjb kbn|kya{lmh* ah b~gbjjbh{ ybplbv m` {nb apaljaijb jl{bya{ryb naw

ibbh uby`mycbk i| Kajim b{ aj( [nlw urijlga{lmh b~aclhbk ajj m` {nb w{rklbw uby{alhlhf {m {nb b``bg{w m`

gyba{lhb mh `jrlk pmjrcb* `jrlk klw{ylir{lmh* {nbycmybfrja{my| ybwumhwbw* ahk wruujbcbh{a{lmh lh gmh{ymjjbk

nm{ my nrclk gmhkl{lmhw aw vbjj aw krylhf b~byglwb lh kbn|kya{bk lhklplkrajw( M` {nb 19 w{rklbw ybplbvbk*

hm{ mhb wrffbw{bk {na{ g{yba{lhb lhgybawbw {nb ylwd m` kbn|kya{lmh my crwgjb gyacuw( Cah| m` {nbc

ag{rajj| wrffbw{bk {na{ l{ ca| kbgybawb {nb ylwd aw {nb gyba{lhb fymruw lh cah| w{rklbw lhgybawbk {m{ajimk| va{by* jmvbybk gmyb imk| {bcubya{ryb krylhf b~byglwb* ahk lcuympbk ujawca pmjrcb .bhgmryafbk

n|ubyn|kya{lmh, T1

7/31/2019 Creatine Paper

4/10

nbay{* iyalh* {bw{bw aw vbjj aw {nb wdbjb{aj crwgjbw vnlgn auubay {m napb {nb nlfnbw{ a``lhl{| `my ujawca

gyba{lhb T0S( [nbyb b~lw{ {vm lwm`mycw m` ujawca gyba{lhb {yahwumy{byw vnlgn ayb im{n wmklrc ahk gnjmylkb

kbubhkbh{4 Gyba[1 ahk Gyba[9( Gyba[1 lw b~gjrwlpb {m wdbjb{aj crwgjb vnljb Gyba[9 lw jmga{bk uylcaylj|

lh {nb {bw{bw T91S( [nb umwwliljl{| ca| b~lw{ {na{ {nb Gyba[1 {yahwumy{by umwwbwwbw a nlfnby a``lhl{| `my

b~mfbhmrw gyba{lhb* vnlgn ca| b~ujalh {nb fyba{by kbfybb m` gyba{lhb {na{ lw kbumwl{bk vl{nlh wdbjb{aj

crwgjb lh gmcuaylwmh {m m{nby {lwwrbw( [nlw wrwulglmh lw |b{ {m ib gmh`lycbk lh {nb jl{bya{ryb(

Lhwrjlh ahk FJR[; ajwm auubay {m napb akkl{lpb b``bg{w rumh gyba{lhb aiwmyu{lmh lh{m crwgjb*

vl{n w{rklbw {na{ napb uymplkbk gayimn|kya{b ahk Ajuna Jlumlg Aglk lh akkl{lmh {m gyba{lhb ybwrj{lhf lh

fyba{by lh{yacrwgrjay gyba{lhb w{mybw T0S( @ry{nbycmyb* ybwumhwb {m gyba{lhb wruujbcbh{a{lmh paylbw

acmhf lhklplkrajw( L{ naw ibbh gmhgjrkbk {na{ {nmwb vl{n jmvby lhl{laj lh{yacrwgrjay gyba{lhb w{mybw*

fyba{by ubygbh{afb m` {|ub 9 crwgjb `libyw* fyba{by crwgjb gymww wbg{lmhaj ayba* ahk fyba{by `a{ `ybb

caww fbhbyajj| ybwumhk ib{{by {m wruujbcbh{a{lmh T91S(

Mhgb lh {nb gbjj* gyba{lhb lw yaulkj| unmwunmy|ja{bk i| gyba{lhb dlhawb vnlgn wriwbqrbh{j| {yauw l{

vl{nlh {nb gbjj cbciyahb( [nlw lw {nb `a{b m` aimr{ 05#65" m` {m{aj crwgjb gyba{lhb* vl{n {nb ybcalhlhf

w{mybk aw `ybb gyba{lhb( Lhwlkb {nb crwgjb gbjj* gyba{lhb ag{w aw ah mwcmj|{b aw vbjj aw ah A[U ir``by*

urjjlhf va{by lh{m {nb gbjj ahk w{mylhf lhgybawbk acmrh{w m` unmwunmgyba{lhb {m ybujb{b AKU krylhf nlfn

lh{bhwl{| ag{lpl{lbw .a(d(a wriw{ya{b jbpbj unmwunmy|ja{lmh, T0* 16(

7/31/2019 Creatine Paper

5/10

Gyba{lhb u|yrpa{b lw a gmcilha{lmh m gyba{lhb imrhk {m u|yrplg aglk( U|yrplg aglk lw ah

lh{bycbkla{b lh fj|gmj|wlw {na{ naw ibbh wnmvh {m ibhb`l{ bhkryahgb uby`mycahgb lh ya{w( [nbyb`myb* {nb

lkba lw {na{ gmcilhlhf {nb {vm vljj uymplkb a w|hbyflw{lg b``bg{ fyba{by {nah {na{ m` bl{nby gmcumrhk ajmhb(

A w{rk| uby`mycbk i| Pah Wgnr|jbhibyfn b{ aj( ahaj|zlhf {nb b``bg{w m` gyba{lhb u|yrpa{b

wruujbcbh{a{lmh .6f-ka| `my 6 ka|w, lh bhkryahgb a{njb{bw vaw hm{ wnmvh {m ibhb`l{ bhkryahgb my wuylh{

uby`mycahgb lh {yalhbk g|gjlw{w T97S( Ahm{nby w{rk| kmhb mh Mj|culg gahmblw{w `mrhk {na{ jag{a{b

gmhgbh{ya{lmhw kbgybawbk ahk uakkjlhf wubbk lhgybawbk vl{n {nb akkl{lmh m` 6(2 fyacw m` gyba{lhb

u|yrpa{b `my 2 ka| T99S( @lhajj|* a yahkmclzbk kmrijb ijlhkbk ahk ujagbim gmh{ymjjbk {ylaj gmcuaybk {nb

b``bg{w m` gyba{lhb u|yrpa{b wruujbcbh{a{lmh gmcuaybk {m {ylgyba{lhb gl{ya{b ahk ujagbim lh nbaj{n| |mrhf

a{njb{bw( Lh {nlw w{rk|* `mry vbbdw m` wruujbcbh{a{lmh vaw `mrhk {m lcuympb ca~lcaj lh{bhwl{| nahkfylu

b~byglwb lh gmcuaylwmh {m ujagbim* rh`my{rha{bj|* hm gmcuaylwmh {m cmhmn|kya{b vaw cakb T9;S(

Gyba{lhb gl{ya{b lw ahm{nby gmcilha{lmh m` gyba{lhb ahk ah bhbyf| uymkrglhf cb{aimjlg

lh{bycbkla{b( Gl{ylg aglk lw {nb w{ay{lhf gmcumrhk m` {nb dybiw g|gjb* mry uylcay| abymilg A[U uymkrglhf

ua{nva|( [nbmyb{lgajj|* {nb gmcilha{lmh m` gyba{lhb ahk gl{ya{b vmrjk {nbyb`myb jbak {m lhgybawbk

b~byglwb bhkryahgb lh akkl{lmh {m {nb ibhb`l{w m` gyba{lhb ajmhb( Gyba{lhb gl{ya{b w{rklbw napb wnmvh

wlcljay mr{gmcbw {m {nmwb kmhb mh u|yrpa{b* wnmvlhf a jmaklhf unawb m` 95 fyacw uby ka| {m ibhb`l{

ahabymilg vmydlhf gauagl{| lh nbaj{n| ag{lpb vmcbh* ahk yalwb pbh{lja{my {nybwnmjk krylhf lh{bhwb ag{lpl{|

T92S( [nb lwwrb vl{n {nb auujlga{lmh m` {nbwb w{rklbw lw {na{ hmhb m` {nbc napb gmcuaybk {nb waj{ fymruw

{m a cmhmn|kya{b fymru4 {nbyb`myb a fau ybcalhw lh {nb jl{bya{ryb ib`myb ah| klw{lhg{ ibhb`l{ aimpb {na{ m`

cmhmn|kya{b gah ib wruumy{bk( Ybgbh{ vmyd uby`mycbk i| Oafby b{ aj( klybg{j| gmcuaylhf lwmcmjay

acmrh{w .lh ybfaykw {m gyba{lhb, m` gyba{lhb cmhmn|kya{b* u|yrpa{b* ahk {ylgyba{lhb gl{ya{b vnlgn wnmvbk

{na{ {nb u|yrpa{b waj{ jbk {m wjlfn{j| nlfnby wbyrc jbpbjw m` gyba{lhb T95S( L{ crw{ ib hm{bk {na{ {nlw w{rk|

mhj| b~aclhbk {nb dlhb{lgw a`{by mhb kmwb ahk mhj| nak 0 wriobg{w( @ry{nbycmyb* {nb ar{nmyw gmhgjrkbk

{na{ {nlw wjlfn{ kl``bybhgb vaw rhjldbj| {m gmh`by ah| {ahflijb akpah{afb T95S(

[m ka{b* {nbyb napb hm{ ibbh ah| urijlwnbk {ylajw uby`mycbk mh gyba{lhb n|kymgnjmylkb* fjrgmha{b*

hl{ya{b* mym{a{b* my um{awwlrc-wmklrc gnbja{b( Lh {nb unaycagbr{lgaj lhkrw{y|* n|kymgnjmylkb lw {|ulgajj|

imrhk {m aclhbw {m lhgybawb aqrbmrw wmjriljl{| ahk lw a uymgbww {na{ {|ulgajj| ajjmvw {nb wriw{ahgb {m ib

aiwmyibk cmyb yaulkj| vl{nlh {nb FL {yag{( L{ lw lcumy{ah{ {m hm{b* {nmrfn* {na{ {nlw uyag{lgb naw hm{ ibbhwnmvh {m ybag{ umwl{lpbj| vl{n ajj gmcumrhkw* ahk lh gby{alh gawbw {nb iawb gmcumrhk ajmhb naw ibbh

wnmvh {m umwwbww wrubylmy wmjriljl{| T90S( Gyba{lhb n|kymgnjmylkb* ua{bh{bk i| Uymcbya Nbaj{n lw

caydb{bk aw a wrubylmy `myc m` gyba{lhb aw l{ lw walk {m umwwbw {nbwb uybplmrwj| cbh{lmhbk {yal{w m` NGJ

imrhk aclhbw4 lhgybawbk aqrbmrw wmjriljl{| ahk aiwmyu{lmh ya{bw( Ibgarwb m` {nbwb uryumy{bk {yal{w l{ lw

wrffbw{bk {na{ l{ mhj| ybqrlybw clgymkmwlhf lh gmcuaylwmh {m gybal{hb cmhmn|kya{b {m a{{alh {nb wacb

ibhb`l{w T96S( [nbyb ayb hm{ ah| w{rklbw gryybh{j| urijlwnbk {m pajlka{b {nbwb gjalcw(

Lh {nb gnbclgaj w|h{nbwlw lhkrw{y|* mym{a{b lw gmccmhj| rwbk aw a ilmapaljailjl{| bhnahgby ahk

imrhk {m clhbyajw wrgn aw gajglrc* cafhbwlrc* um{awwlrc* zlhg* b{gT9>S CAH Wumy{w* {nb

cahr`ag{ryby vnm nmjkw a ua{bh{ mh gyba{lhb mym{a{b* gjalcw {na{ {nb akkl{lmh m` mym{lg aglk `ry{nby

lcuympbw rumh {nb byfmfbhlg b``bg{w m` gyba{lhb {nymrfn calh{alhlhf lh{yagbjjrjay A[U w{mybw* bjbpa{lhf

fj|gmfbh w{mybw* ahk ag{lhf aw a uN ir``by ahk gbjj pmjrclzby T9

7/31/2019 Creatine Paper

6/10

Fjrgmhlg aglk lw a ha{ryajj| mggryylhf lh{bycbkla{b lh fjrgmwb cb{aimjlwc {na{ lw {|ulgajj| rwbk aw

a gayylby lh clhbyaj hr{yl{lmh( L{ lw rhgby{alh aw {m vn| gyba{lhb fjrgmha{b lw uryumy{bk {m bhnahgb b~byglwb

uby`mycahgb m{nby {nah {nb uybplmrwj| bw{aijlwnbk {ylajw vnlgn napb wnmvh fjrgmwb akclhlw{ya{lmh lh

akkl{lmh {m gyba{lhb {m uymplkb akkl{lpb b``bg{w rumh {lwwrb gyba{lhb ru{adb( Hm {ylajw b~lw{ {na{ napb

ahaj|zbk {nb lcujbcbh{a{lmh m` gyba{lhb fjrgmha{b lh nrcahw(

@lhajj|* gnbja{bw `myc ha{ryaj gmcujb~bw vl{nlh {nb imk| ib{vbbh cb{aj lmhw ahk aclhm aglkwuybpbh{lhf {nb gnbja{bk clhbyajw `ymc iblhf urjjbk ava| i| m{nby bjbcbh{w my lmhw uybwbh{ lh {nb

w|w{bc( A fmmk b~acujb m` {nb ilmjmflgaj lcumy{ahgb m {nlw lw {nb w{yrg{ryb m` nbcmfjmilh( Nbcmfjmilh

lw a gnbja{b gmh{alhlhf a gbh{yaj lymh lmh {lfn{j| imrhk {m wryymrhklhf hl{ymfbhw( [nlw lh{byag{lmh uybpbh{w

{nb lymh `ymc klwjmkflhf vnbh l{ lh{byag{w vl{n cmjbgrjay m~|fbh* ajjmvlhf nbcmfjmilh {m ag{ aw ah m~|fbh

gayylby ib{vbbh {lwwrbw T79S( [m ka{b* wmklrc ahk um{awwlrc gyba{lhb gnbja{bw napb hm{ ibbh w{rklbk lh

nrcahw( [nbyb ayb* nmvbpby* {vm w{rklbw {na{ napb ahaj|zbk {nb b `bg{w m` cafhbwlrc gyba{lhb gnbja{b

lh a{njb{bw( A 9557 w{rk| kmhb i| Iyljja b{ aj(* gmcuaybk {nb b``bg{w m` gyba{lhb cafhbwlrc gnbja{b .2 f

gyba{lhb gnbja{bk vl{n >55 cf cafhbwlrc,* gyba{lhb ujrw cafhbwlrc m~lkb .2 f gyba{lhb umvkby cl~bk

vl{n >55 cf cafhbwlrc m~lkb umvkby,* ahk a caj{mkb~{ylh ujagbim lh nbaj{n| 1< {m 9; |bay mjk wriobg{w(

Im{n gyba{lhb fymruw lhgybawbk ubad {myqrb* umvby* ahk {m{aj imk| va{by gmcuaybk {m ujagbim ir{ {nb

cafhbwlrc gnbja{b fymru b~ubylbhgbk wlfhl`lgah{j| fyba{by lhgybawbw lh lh{yagbjjrjay va{by ahk ubad

{myqrb T77S( L{ lw lcumy{ah{ {m hm{b {na{ {nb u pajrb `my ubad {myqrb vaw (50 lh {nb gyba{lhb $ cafhbwlrc

fymru ahk (5; lh {nb gyba{lhb cf gnbja{b fymru wm {nbwb ayb hm{ jldbj| {m ib kl``bybhgbw {na{ vmrjk ib

hm{lgbaijb lh {nb ybaj vmyjk( A cmyb ybgbh{ w{rk| i| Wbjwi| b{ aj( ahaj|zbk {nb b `bg{w m` a jmv kmwb .9(2

f, gyba{lhb* gyba{lhb Cf gnbja{b .9(2 f,* ahk ujagbim fymru mh lcuympbcbh{w lh 1 ybu ca~ ahk {m{aj vmyd

uby`mycbk lh 71 gmjjbfb afb cbh( Gmcuaybk {m {nb ujagbim* im{n gyba{lhb fymruw wlfhl`lgah{j| lhgybawbk

{m{aj vmyd uby`mycbk ir{ {nbyb vbyb hm kl``bybhgbw ib{vbbh fymruw mh ah| m{nby paylaijbw cbawrybk

T7;S( Aw {nb b``bg{w m` gyba{lhb gnbja{b wruujbcbh{w ayb hm{ |b{ kb`lhl{lpb* cmyb vmyd hbbkw {m ib kmhb {m

kb{byclhb l` a fyba{by byfmfbhlg ibhb`l{ b~lw{w vl{n {nbly rwb(

Dyb#Ajdj|h lw a gmcilha{lmh m` ajdajlhb umvkbyw ahk gyba{lhb `mycrja{bk vl{n {nb lh{bh{ m`lhgybawlhf {nb iawlgl{| m` {nb ybwrj{lhf cl~{ryb {m vl{nlh {nb yahfb m` 6#1; mh {nb uN wgajb( [nb gjalc lw

cakb {na{ gyba{lhb lw yaulkj| gmhpby{bk {m gyba{lhlhb lh aglklg bhplymhcbh{w* {nrw yalwlhf {nb uN m`

gyba{lhb ib`myb l{ lh{byag{w vl{n {nb aglklg bhplymhcbh{ m` {nb w{mcagn vljj ajjmv l{ {m ybwlw{ gmhpbywlmh {m

gyba{lhlhb* ajjmvlhf fyba{by gyba{lhb {m ybagn w|w{bclg glygrja{lmh T72S( L{ lw lcumy{ah{ {m hm{b {na{ gyba{lhb

naw ibbh wnmvh lh hrcbymrw urijlwnbk w{rklbw {m gjbay {nb w{mcagn ahk ib aiwmyibk lh{ag{4 {nrw {nbwb

gjalcw ayb hm{ wruumy{bk i| {nb b~lw{lhf jl{bya{ryb T1*7*95S( @ry{nbycmyb* {nbyb ayb |b{ {m ib ah| ubby

ybplbvbk w{rklbw urijlwnbk mh Dyb#Ajdj|h my l{w b``lg{lpbhbww lh nrcahw(

Bw{byl`lga{lmh lw ahm{nby uymgbww {|ulgajj| rwbk lh {nb unaycagbr{lgaj lhkrw{y| {m lhgybawb {nb

ilmapaljailjl{| m` kyrfw vl{n hm{mylmrwj| ummy aiwmyu{lmh( Wuljjahb b{ aj( urijlwnbk {nb `lyw{ ybplbv gyl{lgajj|awwbwwlhf {nb dlhb{lgw m` gyba{lhb b{n|j bw{by wruujbcbh{a{lmh lh 75 |mrhf* nbaj{n| cajbw( Lh {nlw w{rk|*

{nb gyba{lhb b{n|j bw{by fymru klk hm{ mr{uby`myc {nb gyba{lhb cmhmn|kya{b fymru MY {nb caj{mkb~{ylh

ujagbim( @ry{nbycmyb* gyba{lhlhb pajrbw vbyb nlfnbw{ lh {nb b{n|j bw{by wruujbcbh{bk fymru vl{nmr{

wlfhl`lgah{ lhgybawbw lh wbyrc my crwgjb gyba{lhb jbpbjw T70S( [nb ar{nmyw gmhgjrkbk {na{ gyba{lhb b{n|j

bw{by lw jldbj| kbfyakbk {m gyba{lhlhb vl{nlh {nb FL {yag{ aw l{ lw rhw{aijb lh jmv uN yahfbw* uybplmrw vmyd

wruumy{w {nlw gmhgjrwlmh T76S(

7/31/2019 Creatine Paper

7/10

Gyba{lhmj#M#Unmwuna{b lw hm{ ag{rajj| gyba{lhb lh a {bgnhlgaj wbhwb ir{ lw uryumy{bk {m ag{ aw l{w

uybgrywmy* iblhf cb{aimjlzbk vl{nlh {nb imk| {m myc gyba{lhb T7>S( A wlhfjb w{rk| kmhb lh {nb wbpbh{lbw

uymplkbk `bcajb ua{lbh{w vl{n lh{yacrwgrjay ahk lh{yapbhmrw kmwbw m` gyba{lhmj ahk cbawrybk gnahfbw lh

nahkfylu w{ybhf{n( Gyba{lhmj akclhlw{ya{lmh klk jbak {m wlfhl`lgah{j| lcuympbk nahkfylu w{ybhf{n T7#90(

7/31/2019 Creatine Paper

8/10

[nb wbgmhk w{rk| ybgbh{j| urijlwnbk lh {nb Omryhaj m` W{ybhf{n ahk Gmhkl{lmhlhf Ybwbaygn wlcuj|

gmcuaybk a UBF gyba{lhb fymru {m a ujagbim fymru T;7S( Im{n fymruw vbyb rh{yalhbk uylmy {m {nb w{rk| (

Miplmrwj|* {nb mr{gmcb vaw {na{ {nb akkl{lmh m` UBF gyba{lhb lcuympbk 1 ybu ca~ w{ybhf{n* ir{ vl{nmr{

{nb gmcuaylwmh {m a cmhmn|kya{b fymru* {nlw w{rk| kmbw hm{ uymplkb crgn lh {bycw m` wruumy{lhf ka{a(

[nb w{rklbw {na{ napb ibbh uby`mycbk mh gyba{lhb cmhmn|kya{b km hm{ wruumy{ {nb hbbk `my hmpbj

`mycrja{lmhw hmy km {nb| wruumy{ ah| m` {nb ayfrcbh{w {nb wruujbcbh{ lhkrw{y| gmh{lhrajj| rwbw {m

wriw{ah{la{b {nbly w{a{bcbh{w( Rj{lca{bj| ajj {|ubw m` gyba{lhb alc {m aggmcujlwn {nb wacb fmaj4 lhgybawb

ujawca gyba{lhb aw crgn aw umwwlijb* wa{rya{b crwgjb gyba{lhb w{mybw* ahk uymkrgb wlfhl`lgah{ lhgybawbw

lh w{ybhf{n ahk umvby( L` vb ybplwl{ {nb ahaj|wlw {na{ naw ibbh kmhb i| Wgmgn b{ aj( vnlgn naw kb{byclhbk

{nb caomy `ag{myw {na{ klg{a{b a umwl{lpb ybwumhwb {m gyba{lhb wruujbcbh{a{lmh .jmvby lhl{laj lh{yacrwgrjay

gyba{lhb w{mybw* fyba{by ubygbh{afb m` {|ub 9 crwgjb `libyw* fyba{by crwgjb gymww wbg{lmhaj ayba* ahk

fyba{by `a{ `ybb caww, vb gah wubgrja{b {na{ l` ah lhklplkraj kmbw hm{ ybwumhk {m gyba{lhb cmhmn|kya{b*

{nb| vljj hm{ jldbj| ybwumhk {m m{nby payla{lmhw( Lh m{nby vmykw* {nb jlcl{lhf `ag{myw auubay {m ib vl{nlh {nb

lhklplkraj* hm{ {nb uymuby{lbw m` {nb gmcumrhk(

Aj{nmrfn {nb aqrbmrw wmjriljl{| m` gyba{lhb gah ib lcuympbk* ahk ujawca gyba{lhb ca| ib wjlfn{j|

lhgybawbk vl{n hmpbj `mycw m` gyba{lhb* {nbwb napb hm{ uympbh {m jbak {m ah| cbawrybaijb kl``bybhgbw lh

b~byglwb uby`mycahgb vnbh gmcuaybk {m cmhmn|kya{b( Gyba{lhb imrhk {m cb{aimjlg lh{bycbkla{bw ca|

gmh`by wmcb akkl{lmhaj bhkryahgb b~byglwb ibhb`l{w ir{ l{ crw{ ib w{ybwwbk {na{ {nlw uymgbww jbakw {m jbww

uryb gyba{lhb mh a fyac uby fyac iawlw(

L{ lw gjbay {na{ cmyb vmyd crw{ ib kmhb {m kb{byclhb l` {nbyb ayb ah| akpah{afbw {m hmpbj `mycw m`

gyba{lhb( A{ {nlw umlh{ {nb cmhmn|kya{b paylb{| ybcalhw {nb fmjk w{ahkayk( Aj{byha{lpb `mycw {na{ umwwbww

wmcb wjlfn{ wruumy{lhf bplkbhgb lhgjrkb gyba{lhb gnbja{b* UBF gyba{lhb ahk gby{alh gyba{lhb waj{w( [nbwb

aj{byha{bw napb hm{ ibbh wnmvh {m ib wrubylmy {m cmhmn|kya{b lh AH\ m` {nb {ylajw uby`mycbk ir{ ca|

m``by wmcb aj{byha{lpb ibhb`l{w wrgn aw? kbgybawbk FL w|cu{mcw ahk wjlfn{j| lhgybawbk lh{yagbjjrjay va{by

yb{bh{lmh( L{ crw{ ib gmhwlkbybk* {nmrfn* {na{ ajj aj{byha{lpb `mycw ayb {|ulgajj| aggmcuahlbk vl{n a

fyba{by uylgb {af( L{ lw rj{lca{bj| |mry kbglwlmh aw {nb gmhwrcby l` {nbwb umwwlijb clhmy ibhb`l{w ayb vmy{n

{nb akkbk b~ubhwb(

7/31/2019 Creatine Paper

9/10

Yb`bybhgbw

1( Vljjlacw* C(N(* Y(I( Dyblkby* ahk O(K( Iyahgn* Gyba{lhb? {nb umvby wruujbcbh{( 1

7/31/2019 Creatine Paper

10/10

99( Oafby* Y(* b{ aj(*Ahaj|wlw m` {nb b``lgag|* wa`b{|* ahk ybfrja{my| w{a{rw m` hmpbj `mycw m` gyba{lhb(

Aclhm Aglkw* 9511( ;5.2,? u( 1707(

97( Pah Wgnr|jbhibyfn* Y(* C( Pah Jbbcur{{b* ahk U( Nbwubj* B``bg{w m` myaj gyba{lhb#u|yrpa{b

wruujbcbh{a{lmh lh g|gjlhf uby`mycahgb( Lh{ O Wumy{w Cbk* 9557( 9;.9,? u( 1;;#25(

9;( Oafby* Y(* b{ aj(* [nb b``bg{w m` gyba{lhb u|yrpa{b ahk gyba{lhb gl{ya{b mh uby`mycahgb krylhf nlfn

lh{bhwl{| b~byglwb( O Lh{ Wmg Wumy{w Hr{y* 955>( 2? u( ;(

92( Fyab`* O(J(* b{ aj(* [nb b``bg{w m` `mry vbbdw m` gyba{lhb wruujbcbh{a{lmh ahk nlfn#lh{bhwl{|

lh{bypaj {yalhlhf mh gayklmybwulya{my| `l{hbww? a yahkmclzbk gmh{ymjjbk {ylaj( O Lh{ Wmg Wumy{w Hr{y*

955(

90( Cl|azadl* W(* C( Mwnlia* ahk [( Hakal* Uybgar{lmh mh rwb m` n|kymgnjmylkb waj{w lh unaycagbr{lgaj

`mycrja{lmh( Omryhaj m` Unaycagbr{lgaj Wglbhgbw* 11( 65.0,? u( 2