COUNTRY PAPER on "BIOTECHNOLOGY" presented in the SECOND EXPERT GROUP MEETING ON BINASIA HELD IN...
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Transcript of COUNTRY PAPER on "BIOTECHNOLOGY" presented in the SECOND EXPERT GROUP MEETING ON BINASIA HELD IN...
COUNTRY PAPERon
"BIOTECHNOLOGY"
presented in the
SECOND EXPERT GROUP MEETING ON BINASIAHELD IN BANGKOK, THAILAND
FROM JANUARY 24-25, 2006
PREPARED BY
PROF. DR. S. RIAZUDDINDirector
Centre Of Excellence Molecular BiologyThokar Niaz Baig, Canal Bank Road
Lahore
GENES CAN BE ISOLATED FROM BACTERIA, VIRUSES,
FUNGI, PLANTS OR ANIMALS AND MADE TO EXPRESS IN
CHOICE HOSTS
IT WILL SOME DAY BE POSSIBLE TO MANIPULATE GENES
FOR ALMOST ANY CHARACTER RESULTING IN THE PRODUCTION
OF DESIRED TRAITS ON WHATEVER SCALE WE DESIRE
PRODUCTS AND SERVICES OF BIOTECHNOLOGY ARE EMERGING
AS A VERY SUBSTANTIAL REVENUE-GENERATING SOURCE
FOR THE ECONOMIES OF DEVELOPED NATIONS
BIOTECH MARKET ANALYSIS OF DIFFERENT BIOTECH SECTORS
a) Genetically Modified (GM) Crops
b) Biopharmaceuticals
c) Molecular Diagnostic
CURRENT STATUS OF BIOTECH RESEARCH IN
PAKISTAN
Centre of Excellence in Molecular Biology (CEMB)/ Centre for Applied Molecular Biology
University of the Punjab, Lahore
Bt transgenic rice and Bt cotton.
Disease free seeds of potatoes, sugarcane and gladiolus flowers.
Bt bioinsecticide, mycopesticide.
Prenatal diagnosis of -thalassemia.
DNA Typing for crime investigation and parenthood identification,
PCR based diagnosis of infectious diseases (hepatitis B&C and tuberculosis) – services and kits.
Human recombinant proteins – interferon alpha 2a and insulin.
National Institute of Biotechnology & Genetic Engineering (NIBGE),
Jhang Road, Faisalabad BioPower developed to support growth of different grains, fodder
legumes, cereals, cotton etc.
DNA purity test for basmati rice (Export National focal point).
Production of industrial Enzymes.
PCR/ DNA based diagnostic tests for cotton/ banana viruses.
Inocula for methane and ethanol production.
Test for formaldehyde, heavy metal and microbiological content for export goods in export goods.
Broad spectrum virus resistant GM cotton and GM tomato. oduction of citric acid and Alpha-amylase.
Model process for coal desulphurisation at industrial scale.
Biotechnological process for recovery of copper from indigenous ores.
Microbial consortia for waste treatment for various industries
Centre for Molecular Genetics (CMG), University of Karachi, Karachi
Biological filters using indigenous resources for the treatment/detoxification of industrial effluents. This technology could be commercialized to recycle the waste matter and recovery of heavy metals.
Development of oil degrading bacteria.
Production of biodegradable plastic (PHA) by bacteria.
Production of alginate and water absorbing polysaccharides by bacteria using the sugar- cane waste. These could be used for improving fertility of agricultural lands, for preparing materials like tissue papers and baby diapers.
Bacterial production of dextran.
Production of antimicrobial compounds from marine bacteria (pharmaceutical industry).
Development of plant growth promoting bacteria which have the ability to degrade complex phosphate compounds to liberate free phosphorus and produce plant growth hormones.
ISSUES AND CONCERNS REGARDING
COMMERCIALIZATION OF BIOTECHNOLOGY PRODUCTS AND
PROCESSES
IMPACT ON TRADE OF ASIAN COUNTRIES
(a) Switching on to new raw material base may actually be effectuated much quicker than in the past,
(b) a large number of commodities will undergo major changes in supply and demand at the same time, and
(c) alternative sources for foreign exchange earnings may be more limited than at other historical junctures.
INHERENT CONSTRAINTS IN THE PROMOTION OF
APPLICATIONS OF BIOTECHNOLOGY IN ASIAN COUNTRIES
VARIOUS SEGMENTS INVOLVED IN MARKETING LABORATORY RESEARCH
Science Managers (Based on needs – Technical feasibility vizs-à-vis infrastructure and market trends – which other institions are working to produce it – value addition / cost economics)
Conceiving a project Identification of a Product/Process
1
Laboratory Research
Sound Scientific Plan (Molecular Biology)2
Upscale; Fermentation
Chemical Engineers (Economy, bye-product, other products)
3
Formulation Ease of Distribution (Shelf Life; persistence, mode of application)
4
Field Trial5 Compliance with
approval/ Regulatory Procedure
Packaging & Marketing By the Non–biologists,
Attractive/ aggressive
6
Legal Protection/ Patent
PROPOSED STRATEGY TO REAP A HARVEST OF
BIOTECHNOLOGY
BIO-FORUM 2006MARCH 13-15, 2006
The Centres for Molecular Biology, University of the Punjab, Lahore, Pakistan and PISELLI CONSULTING S.L. Barcelona, Spain, will jointly organize “Bioforum 2006” in Lahore, Pakistan from March 13-16, 2006. This will be the first partnering conference held in Pakistan and will bring together industry and academia from Pakistan, neighboring India, and Middle-Eastern countries.
Participants include professionals, company officials, regulatory affairs and project management.
The forum will also include
Concurrent Workshops and Plenary Lecture For more information please visit
www.cemb.edu.pk/Bioforum2006
VENUE
National Centre of Excellence in Molecular BiologyUniversity of the Punjab
87-West Canal Bank Road, Thokar Niaz BaigLAHORE-53700LAHORE-53700, Pakistan
Tel: 042-5421235Fax: 042-542-1316
Email: [email protected]
PROGRAMME www.cemb.edu.pk/Bioforum2006
PLENARY LECTURESGLOBALIZATION OF R&D EFFORTS THROUGH COLLABORATIVE ENDEAVOURS.
OUTSOURCING AS A MEANS TO ACTIVATE GLOBALIZATION
OPTIMIZATION OF RETURNS FROM UNIVERSITY RESEARCH – TECHNICAL & LEGAL MEASURES
ENFORCEMENT OF PATENTS IN PAKISTAN
FUNDING FOR PAKISTAN’S RESEARCH & DEVELOPMENT IN LIFE SCIENCES
REGULATORY ISSUES An Overview of cGMP Requirements by USFDA / European FDA (legal principles and implementation tools) Introduction to validation Regulatory/ user requirements Good engineering practices Protocols
cGMP APPLICATIONS Concepts and regulations Contamination and cross contamination issues/ drug safety Design of GMP bio-containment facilities for pharmaceutical and vaccine production Risk and impact assessment Impact on operation
CONCURRENT WORKSHOPS
I: Vaccines (Hepatitis B &C)II: siRNA Technology as a new Therapeutic ToolIII: Stem Cells & Regenerative MedicineIV: Bioethical issues in Research & Clinical TrialsV: Detection of chemical, biological and GMO’s toxic materials in the environment and food chain
REGISTRATION OF PHARMACEUTICALS IN PAKISTANCLINICAL TRIALS
APPROVAL PROCESS OF PHARMACEUTICALS
PARTNERING SESSIONS AMONG UNIVERSITY SCIENTISTS AND ENTREPRENEURS
Agriculture Health Industry
THE CENTRE FOR MOLECULAR BIOLOGY COORDIALLY INVITES YOU
TO PARTICIPATE IN THE BIOFORUM EXHIBITION
LOCAL HOSPITALITY WILL BE PROVIDED BY THE ORGANIZORS
MARCH 13-15, 2006
IF YOU WISH TO PARTICIPATE IN THE EXHIBITIONplease complete the following information
for your product/ process
and send it to [email protected]; [email protected]
THANK YOU