Correction of Slide #39 (I3 Session #3).pdf

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Abnormal Blood Iron Test Results Iron Ferri5n Transferrin satura5on (%) TIBC Transferrin Hemoglobin Hemochromatosis Normal Iron deficiency anemia Sideroblas5c anemia Anemia of chronic disease Normal or Normal Hookworm infec5on Iron: serum iron level represents the amount of circula3ng iron that is bound to transferrin (normal: 50:150 ug/dL) TIBC: indirect measure of the amount of circula3ng apotransferrin (normal: 300:360 ug/dL) Transferrin Satura5on: (Normal: 15:45%. Note: in pa3ents with anemia of chronic diseases, transferrin level is decreased) ! Level <15%: indicates iron deficiency ! Level 45:100%: indicates iron overload Ferri5n: represents the total body iron store (Normal female: 20:200 ug/L; Normal male: 20:300 ug/) ! Level <12: indicates iron deficiency ! Level 300:4000: indicates iron overload BMJ 2013; 346:f3154 N Engl J Med 2005;352:1011:23

Transcript of Correction of Slide #39 (I3 Session #3).pdf

Page 1: Correction of Slide #39 (I3 Session #3).pdf

Abnormal)Blood)Iron)Test)Results)

Iron) Ferri5n) Transferrin)satura5on)(%)) TIBC) Transferrin) Hemoglobin)

Hemochromatosis) ↑) ↑) ↑) ↓) ↓) Normal)

Iron)deficiency)anemia) ↓) ↓) ↓) ↑) ↑) ↓)

Sideroblas5c)anemia) ↑) ↑) ↑) ↓) ↓) ↓)

Anemia)of)chronic)disease) ↓) Normal)or)↑) Normal) ↓) ↓) ↓)

Hookworm)infec5on) ↓) ↓) ↓) ↑) ↑) ↓)

Iron:"serum"iron"level"represents"the"amount"of"circula3ng"iron"that"is"bound"to"transferrin"(normal:"50:150"ug/dL)"TIBC:"indirect"measure"of"the"amount"of"circula3ng"apotransferrin"(normal:"300:360"ug/dL)"Transferrin)Satura5on:"(Normal:"15:45%."Note:"in"pa3ents"with"anemia"of"chronic"diseases,"transferrin"level"is"decreased)"!  Level"<15%:"indicates"iron"deficiency"!  Level"45:100%:"indicates"iron"overload"Ferri5n:"represents"the"total"body"iron"store"(Normal"female:"20:200"ug/L;"Normal"male:"20:300"ug/)"!  Level"<12:"indicates"iron"deficiency"!  Level"300:4000:"indicates"iron"overload"

BMJ"2013;"346:f3154"N%Engl%J%Med%2005;352:1011:23"