Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4....

14
Computing Research Association Conference at Snowbird 2000 Slides from a workshop on the topic of http://www.cra.org/Activities/snowbird/00/wk4-1.html “The Relationship Between Computer and Computational Science” presented by Sidney Karin, University of California, San Diego

Transcript of Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4....

Page 1: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

Computing Research AssociationConference at Snowbird 2000

Slides from a workshopon the topic of

httpwwwcraorgActivitiessnowbird00wk4-1html

ldquoThe Relationship Between Computerand Computational Sciencerdquo

presented by

Sidney KarinUniversity of California San Diego

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

CRA Conference Snowbird 2000Snowbird Utah

July 11 2000

Sid Karin DirectorNPACI and SDSC

The Relationship Between ComputerScience and Computational Science

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputer science is the computer

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputational biology is living systems

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputer science is the computer

bull The object of intellectual curiosity incomputational biology is living systems

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Theory Theory

The Computational Science Continuum

SimulationSimulation

ExperimentExperiment

Data-intensive computing(mining)

Data-intensive

computing(assimilation)

Numericallyintensivecomputing

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

MICE Transparent Supercomputingbull Molecular Interactive

CollaborativeEnvironment

bull Gallery allowsresearchers studentsto search for visualizeand manipulatemolecular structures

bull Integrates key SDSCtechnological strengthsbull Biological databasesbull Transparent

supercomputingbull Web-based Virtual Reality

Modeling Language

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Visualization by Donna Cox Bob Patterson NCSAFrom ldquoCosmic Voyagerdquo (Smithsonian IMAX)

bull Virtual Director in CAVEfor Choreography of Data

bull 1000-Hour SDSCSupercomputer Run toGenerate Data

bull Tens of Thousands ofHours of NCSA SGI Timeto Render Data

bull Cross-Country Transfer of65 GB of data to IMAX Film

Supercomputers Networks and Virtual Reality-- Sharing Science with 80 Million People

NATIONAL COMPUTATIONAL SCIENCE ALLIANCE

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Brain Mappingbull One brain = a lot of data

bull At full-color micrometerresolution one brain fills45 petabytes

bull Mapping the brain will helpunderstand memoryconsciousness sleep agingbull Insight about brain structure-

function relationshipsin health and disease

bull Federating geographically distributed collections and toolsfor data exploration comparison and simulation

bull Involves all NPACI technology thrusts

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

SDSC Storage Resource Broker amp Meta-data Catalog

SDSC SRB

ADSM HPSS DB2 Oracle Unix

Application

File SID DBLobj SID Obj SID

MCAT

Dublin Core

Resource

User

ApplicationMeta-data

RemoteProxies

DataCutter

Third-partycopy

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

ldquoCollectionrdquo Management Federation of BrainData

CCB Montana SUSurface atlas Van Essen Lab

NCMIR UCSDstereotaxic atlas LONI

MCell CNL Salk

ANATOM

PROTLOC

Result (VML)

MODEL-BASED Mediation

Result (XMLXSLT)

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 2: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

CRA Conference Snowbird 2000Snowbird Utah

July 11 2000

Sid Karin DirectorNPACI and SDSC

The Relationship Between ComputerScience and Computational Science

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputer science is the computer

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputational biology is living systems

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputer science is the computer

bull The object of intellectual curiosity incomputational biology is living systems

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Theory Theory

The Computational Science Continuum

SimulationSimulation

ExperimentExperiment

Data-intensive computing(mining)

Data-intensive

computing(assimilation)

Numericallyintensivecomputing

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

MICE Transparent Supercomputingbull Molecular Interactive

CollaborativeEnvironment

bull Gallery allowsresearchers studentsto search for visualizeand manipulatemolecular structures

bull Integrates key SDSCtechnological strengthsbull Biological databasesbull Transparent

supercomputingbull Web-based Virtual Reality

Modeling Language

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Visualization by Donna Cox Bob Patterson NCSAFrom ldquoCosmic Voyagerdquo (Smithsonian IMAX)

bull Virtual Director in CAVEfor Choreography of Data

bull 1000-Hour SDSCSupercomputer Run toGenerate Data

bull Tens of Thousands ofHours of NCSA SGI Timeto Render Data

bull Cross-Country Transfer of65 GB of data to IMAX Film

Supercomputers Networks and Virtual Reality-- Sharing Science with 80 Million People

NATIONAL COMPUTATIONAL SCIENCE ALLIANCE

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Brain Mappingbull One brain = a lot of data

bull At full-color micrometerresolution one brain fills45 petabytes

bull Mapping the brain will helpunderstand memoryconsciousness sleep agingbull Insight about brain structure-

function relationshipsin health and disease

bull Federating geographically distributed collections and toolsfor data exploration comparison and simulation

bull Involves all NPACI technology thrusts

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

SDSC Storage Resource Broker amp Meta-data Catalog

SDSC SRB

ADSM HPSS DB2 Oracle Unix

Application

File SID DBLobj SID Obj SID

MCAT

Dublin Core

Resource

User

ApplicationMeta-data

RemoteProxies

DataCutter

Third-partycopy

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

ldquoCollectionrdquo Management Federation of BrainData

CCB Montana SUSurface atlas Van Essen Lab

NCMIR UCSDstereotaxic atlas LONI

MCell CNL Salk

ANATOM

PROTLOC

Result (VML)

MODEL-BASED Mediation

Result (XMLXSLT)

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 3: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputer science is the computer

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputational biology is living systems

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputer science is the computer

bull The object of intellectual curiosity incomputational biology is living systems

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Theory Theory

The Computational Science Continuum

SimulationSimulation

ExperimentExperiment

Data-intensive computing(mining)

Data-intensive

computing(assimilation)

Numericallyintensivecomputing

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

MICE Transparent Supercomputingbull Molecular Interactive

CollaborativeEnvironment

bull Gallery allowsresearchers studentsto search for visualizeand manipulatemolecular structures

bull Integrates key SDSCtechnological strengthsbull Biological databasesbull Transparent

supercomputingbull Web-based Virtual Reality

Modeling Language

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Visualization by Donna Cox Bob Patterson NCSAFrom ldquoCosmic Voyagerdquo (Smithsonian IMAX)

bull Virtual Director in CAVEfor Choreography of Data

bull 1000-Hour SDSCSupercomputer Run toGenerate Data

bull Tens of Thousands ofHours of NCSA SGI Timeto Render Data

bull Cross-Country Transfer of65 GB of data to IMAX Film

Supercomputers Networks and Virtual Reality-- Sharing Science with 80 Million People

NATIONAL COMPUTATIONAL SCIENCE ALLIANCE

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Brain Mappingbull One brain = a lot of data

bull At full-color micrometerresolution one brain fills45 petabytes

bull Mapping the brain will helpunderstand memoryconsciousness sleep agingbull Insight about brain structure-

function relationshipsin health and disease

bull Federating geographically distributed collections and toolsfor data exploration comparison and simulation

bull Involves all NPACI technology thrusts

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

SDSC Storage Resource Broker amp Meta-data Catalog

SDSC SRB

ADSM HPSS DB2 Oracle Unix

Application

File SID DBLobj SID Obj SID

MCAT

Dublin Core

Resource

User

ApplicationMeta-data

RemoteProxies

DataCutter

Third-partycopy

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

ldquoCollectionrdquo Management Federation of BrainData

CCB Montana SUSurface atlas Van Essen Lab

NCMIR UCSDstereotaxic atlas LONI

MCell CNL Salk

ANATOM

PROTLOC

Result (VML)

MODEL-BASED Mediation

Result (XMLXSLT)

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 4: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputational biology is living systems

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputer science is the computer

bull The object of intellectual curiosity incomputational biology is living systems

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Theory Theory

The Computational Science Continuum

SimulationSimulation

ExperimentExperiment

Data-intensive computing(mining)

Data-intensive

computing(assimilation)

Numericallyintensivecomputing

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

MICE Transparent Supercomputingbull Molecular Interactive

CollaborativeEnvironment

bull Gallery allowsresearchers studentsto search for visualizeand manipulatemolecular structures

bull Integrates key SDSCtechnological strengthsbull Biological databasesbull Transparent

supercomputingbull Web-based Virtual Reality

Modeling Language

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Visualization by Donna Cox Bob Patterson NCSAFrom ldquoCosmic Voyagerdquo (Smithsonian IMAX)

bull Virtual Director in CAVEfor Choreography of Data

bull 1000-Hour SDSCSupercomputer Run toGenerate Data

bull Tens of Thousands ofHours of NCSA SGI Timeto Render Data

bull Cross-Country Transfer of65 GB of data to IMAX Film

Supercomputers Networks and Virtual Reality-- Sharing Science with 80 Million People

NATIONAL COMPUTATIONAL SCIENCE ALLIANCE

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Brain Mappingbull One brain = a lot of data

bull At full-color micrometerresolution one brain fills45 petabytes

bull Mapping the brain will helpunderstand memoryconsciousness sleep agingbull Insight about brain structure-

function relationshipsin health and disease

bull Federating geographically distributed collections and toolsfor data exploration comparison and simulation

bull Involves all NPACI technology thrusts

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

SDSC Storage Resource Broker amp Meta-data Catalog

SDSC SRB

ADSM HPSS DB2 Oracle Unix

Application

File SID DBLobj SID Obj SID

MCAT

Dublin Core

Resource

User

ApplicationMeta-data

RemoteProxies

DataCutter

Third-partycopy

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

ldquoCollectionrdquo Management Federation of BrainData

CCB Montana SUSurface atlas Van Essen Lab

NCMIR UCSDstereotaxic atlas LONI

MCell CNL Salk

ANATOM

PROTLOC

Result (VML)

MODEL-BASED Mediation

Result (XMLXSLT)

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 5: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Relationship Between ComputerScience and Computational Science

bull The object of intellectual curiosity incomputer science is the computer

bull The object of intellectual curiosity incomputational biology is living systems

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Theory Theory

The Computational Science Continuum

SimulationSimulation

ExperimentExperiment

Data-intensive computing(mining)

Data-intensive

computing(assimilation)

Numericallyintensivecomputing

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

MICE Transparent Supercomputingbull Molecular Interactive

CollaborativeEnvironment

bull Gallery allowsresearchers studentsto search for visualizeand manipulatemolecular structures

bull Integrates key SDSCtechnological strengthsbull Biological databasesbull Transparent

supercomputingbull Web-based Virtual Reality

Modeling Language

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Visualization by Donna Cox Bob Patterson NCSAFrom ldquoCosmic Voyagerdquo (Smithsonian IMAX)

bull Virtual Director in CAVEfor Choreography of Data

bull 1000-Hour SDSCSupercomputer Run toGenerate Data

bull Tens of Thousands ofHours of NCSA SGI Timeto Render Data

bull Cross-Country Transfer of65 GB of data to IMAX Film

Supercomputers Networks and Virtual Reality-- Sharing Science with 80 Million People

NATIONAL COMPUTATIONAL SCIENCE ALLIANCE

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Brain Mappingbull One brain = a lot of data

bull At full-color micrometerresolution one brain fills45 petabytes

bull Mapping the brain will helpunderstand memoryconsciousness sleep agingbull Insight about brain structure-

function relationshipsin health and disease

bull Federating geographically distributed collections and toolsfor data exploration comparison and simulation

bull Involves all NPACI technology thrusts

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

SDSC Storage Resource Broker amp Meta-data Catalog

SDSC SRB

ADSM HPSS DB2 Oracle Unix

Application

File SID DBLobj SID Obj SID

MCAT

Dublin Core

Resource

User

ApplicationMeta-data

RemoteProxies

DataCutter

Third-partycopy

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

ldquoCollectionrdquo Management Federation of BrainData

CCB Montana SUSurface atlas Van Essen Lab

NCMIR UCSDstereotaxic atlas LONI

MCell CNL Salk

ANATOM

PROTLOC

Result (VML)

MODEL-BASED Mediation

Result (XMLXSLT)

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 6: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Theory Theory

The Computational Science Continuum

SimulationSimulation

ExperimentExperiment

Data-intensive computing(mining)

Data-intensive

computing(assimilation)

Numericallyintensivecomputing

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

MICE Transparent Supercomputingbull Molecular Interactive

CollaborativeEnvironment

bull Gallery allowsresearchers studentsto search for visualizeand manipulatemolecular structures

bull Integrates key SDSCtechnological strengthsbull Biological databasesbull Transparent

supercomputingbull Web-based Virtual Reality

Modeling Language

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Visualization by Donna Cox Bob Patterson NCSAFrom ldquoCosmic Voyagerdquo (Smithsonian IMAX)

bull Virtual Director in CAVEfor Choreography of Data

bull 1000-Hour SDSCSupercomputer Run toGenerate Data

bull Tens of Thousands ofHours of NCSA SGI Timeto Render Data

bull Cross-Country Transfer of65 GB of data to IMAX Film

Supercomputers Networks and Virtual Reality-- Sharing Science with 80 Million People

NATIONAL COMPUTATIONAL SCIENCE ALLIANCE

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Brain Mappingbull One brain = a lot of data

bull At full-color micrometerresolution one brain fills45 petabytes

bull Mapping the brain will helpunderstand memoryconsciousness sleep agingbull Insight about brain structure-

function relationshipsin health and disease

bull Federating geographically distributed collections and toolsfor data exploration comparison and simulation

bull Involves all NPACI technology thrusts

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

SDSC Storage Resource Broker amp Meta-data Catalog

SDSC SRB

ADSM HPSS DB2 Oracle Unix

Application

File SID DBLobj SID Obj SID

MCAT

Dublin Core

Resource

User

ApplicationMeta-data

RemoteProxies

DataCutter

Third-partycopy

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

ldquoCollectionrdquo Management Federation of BrainData

CCB Montana SUSurface atlas Van Essen Lab

NCMIR UCSDstereotaxic atlas LONI

MCell CNL Salk

ANATOM

PROTLOC

Result (VML)

MODEL-BASED Mediation

Result (XMLXSLT)

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 7: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

MICE Transparent Supercomputingbull Molecular Interactive

CollaborativeEnvironment

bull Gallery allowsresearchers studentsto search for visualizeand manipulatemolecular structures

bull Integrates key SDSCtechnological strengthsbull Biological databasesbull Transparent

supercomputingbull Web-based Virtual Reality

Modeling Language

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Visualization by Donna Cox Bob Patterson NCSAFrom ldquoCosmic Voyagerdquo (Smithsonian IMAX)

bull Virtual Director in CAVEfor Choreography of Data

bull 1000-Hour SDSCSupercomputer Run toGenerate Data

bull Tens of Thousands ofHours of NCSA SGI Timeto Render Data

bull Cross-Country Transfer of65 GB of data to IMAX Film

Supercomputers Networks and Virtual Reality-- Sharing Science with 80 Million People

NATIONAL COMPUTATIONAL SCIENCE ALLIANCE

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Brain Mappingbull One brain = a lot of data

bull At full-color micrometerresolution one brain fills45 petabytes

bull Mapping the brain will helpunderstand memoryconsciousness sleep agingbull Insight about brain structure-

function relationshipsin health and disease

bull Federating geographically distributed collections and toolsfor data exploration comparison and simulation

bull Involves all NPACI technology thrusts

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

SDSC Storage Resource Broker amp Meta-data Catalog

SDSC SRB

ADSM HPSS DB2 Oracle Unix

Application

File SID DBLobj SID Obj SID

MCAT

Dublin Core

Resource

User

ApplicationMeta-data

RemoteProxies

DataCutter

Third-partycopy

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

ldquoCollectionrdquo Management Federation of BrainData

CCB Montana SUSurface atlas Van Essen Lab

NCMIR UCSDstereotaxic atlas LONI

MCell CNL Salk

ANATOM

PROTLOC

Result (VML)

MODEL-BASED Mediation

Result (XMLXSLT)

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 8: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Visualization by Donna Cox Bob Patterson NCSAFrom ldquoCosmic Voyagerdquo (Smithsonian IMAX)

bull Virtual Director in CAVEfor Choreography of Data

bull 1000-Hour SDSCSupercomputer Run toGenerate Data

bull Tens of Thousands ofHours of NCSA SGI Timeto Render Data

bull Cross-Country Transfer of65 GB of data to IMAX Film

Supercomputers Networks and Virtual Reality-- Sharing Science with 80 Million People

NATIONAL COMPUTATIONAL SCIENCE ALLIANCE

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Brain Mappingbull One brain = a lot of data

bull At full-color micrometerresolution one brain fills45 petabytes

bull Mapping the brain will helpunderstand memoryconsciousness sleep agingbull Insight about brain structure-

function relationshipsin health and disease

bull Federating geographically distributed collections and toolsfor data exploration comparison and simulation

bull Involves all NPACI technology thrusts

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

SDSC Storage Resource Broker amp Meta-data Catalog

SDSC SRB

ADSM HPSS DB2 Oracle Unix

Application

File SID DBLobj SID Obj SID

MCAT

Dublin Core

Resource

User

ApplicationMeta-data

RemoteProxies

DataCutter

Third-partycopy

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

ldquoCollectionrdquo Management Federation of BrainData

CCB Montana SUSurface atlas Van Essen Lab

NCMIR UCSDstereotaxic atlas LONI

MCell CNL Salk

ANATOM

PROTLOC

Result (VML)

MODEL-BASED Mediation

Result (XMLXSLT)

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 9: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Brain Mappingbull One brain = a lot of data

bull At full-color micrometerresolution one brain fills45 petabytes

bull Mapping the brain will helpunderstand memoryconsciousness sleep agingbull Insight about brain structure-

function relationshipsin health and disease

bull Federating geographically distributed collections and toolsfor data exploration comparison and simulation

bull Involves all NPACI technology thrusts

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

SDSC Storage Resource Broker amp Meta-data Catalog

SDSC SRB

ADSM HPSS DB2 Oracle Unix

Application

File SID DBLobj SID Obj SID

MCAT

Dublin Core

Resource

User

ApplicationMeta-data

RemoteProxies

DataCutter

Third-partycopy

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

ldquoCollectionrdquo Management Federation of BrainData

CCB Montana SUSurface atlas Van Essen Lab

NCMIR UCSDstereotaxic atlas LONI

MCell CNL Salk

ANATOM

PROTLOC

Result (VML)

MODEL-BASED Mediation

Result (XMLXSLT)

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 10: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

SDSC Storage Resource Broker amp Meta-data Catalog

SDSC SRB

ADSM HPSS DB2 Oracle Unix

Application

File SID DBLobj SID Obj SID

MCAT

Dublin Core

Resource

User

ApplicationMeta-data

RemoteProxies

DataCutter

Third-partycopy

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

ldquoCollectionrdquo Management Federation of BrainData

CCB Montana SUSurface atlas Van Essen Lab

NCMIR UCSDstereotaxic atlas LONI

MCell CNL Salk

ANATOM

PROTLOC

Result (VML)

MODEL-BASED Mediation

Result (XMLXSLT)

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 11: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

ldquoCollectionrdquo Management Federation of BrainData

CCB Montana SUSurface atlas Van Essen Lab

NCMIR UCSDstereotaxic atlas LONI

MCell CNL Salk

ANATOM

PROTLOC

Result (VML)

MODEL-BASED Mediation

Result (XMLXSLT)

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 12: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Protein Data Bankbull Worldrsquos single scientific resource for

depositing and searching proteinstructures

bull Protein structure data growingexponentiallybull 10500 structures in PDB todaybull 20000 by the year 2001

bull Vital to the advancement of biologicalsciences

bull Working towards a digital continuumfrom primary data to final scientificpublication

bull Capture of primary data from high-energy synchrotrons (eg StanfordLinear Accelerator Center) requires50Mbps network bandwidth1CD3 The PDBrsquos 10000th structure

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 13: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

Telescience for AdvancedTomography Applications

bull Integrates remote instrumentationdistributed computing federateddatabases image archives andvisualization toolsbull Mark Ellisman UCSDbull Fran Berman UCSDbull Carl Kesselman USC

bull 3-D tomographicreconstruction ofbiological specimens

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech

Page 14: Computing Research Associationarchive.cra.org/Activities/snowbird/00/karin-crawk4-1.pdf · 2012. 4. 4. · NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE SAN DIEGO

NATIONAL PARTNERSHIP FOR ADVANCED COMPUTATIONAL INFRASTRUCTURE

SAN DIEGO SUPERCOMPUTER CENTER

The Digital Skybull Billions of objects can be

detected with optical infraredand radio telescopesbull Tens of terabytes of image and

catalog databull Digital Sky federating four sky

surveys to allow multi-wavelength studies across thedata setsbull DPOSS 2MASS NVSS FIRSTbull Tom Prince Caltech leading

federation effortbull Uses MIX SDSC SRB and NPACI

mass storage systems

A globular cluster from the DPOSSarchive Such clusters provide a minimumage for the universe Image by ThomasHandley Caltech