Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City,...

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Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA

Transcript of Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City,...

Page 1: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Computed Tomography Principles

Ge Wang, Ph.D.Department of Radiology

University of IowaIowa City, Iowa 52242, USA

Page 2: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Learning Objectives

• CT terms• Data acquisition• Basic elements of CT scanner• Scanning modes• Image reconstruction

• Spiral/helical CT• Image resolution and artifacts• Interaction among imaging parameters• Quality assurance• Radiation exposure

Page 3: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

A Little Bit History

Nobel prizesRoentgen (1901): Discovery of X-rays Hounsfield & Cormack (1979): Computed tomography

Page 4: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Computed Tomography Principles

1. Projection measurement

2. Scanning modes

3. Scanner systems

4. Image reconstruction

Page 5: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

X-ray Interactions - Photoelectric Effect

Photoelectric effect results in total absorption ofthe X-ray photon and the emission of a bound electron

(From Aracor)

Page 6: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

X-ray Interactions - Compton Scatter

Compton Scatter results in a free electron &a scattered (less energetic) photon

(From Aracor)

Page 7: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Source- Rotating anode disk- Small focal spot

down to 0.6 mm- Polychromatic beam

Detectors- Xenon (50-60%)- Scintillation (>90%)

Source and Detectors

(From Siemens)

Page 8: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Exponential Attenuation of X-ray

x

No

xio eNN

xio eNN )( 321 Ni

x

X-rays

Attenuatedmore

NoNi

Ni: input intensity of X-rayNo: output intensity of X-ray: linear X-ray attenuation

Page 9: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Ray-Sum of X-ray Attenuation

o

i

kk N

Nx ln

o

i

N

Ndxx ln)(

x

iok

k

eNN

x

NoNi

Ray-sum Line integral

Page 10: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Projection & Sinogram

Sinogramt

Sinogram:All projections

P(t)

f(x,y)

t

y

x

X-rays

Projection:All ray-sums in a direction

Page 11: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Completeness Condition

There exists at least a source on any lineintersecting a cross-section

Page 12: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Computed Tomography Principles

1. Projection measurement

2. Scanning modes

3. Scanner systems

4. Image reconstruction

Page 13: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

First Generation

One detectorTranslation-rotationParallel-beam

Page 14: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Second Generation

Multiple detectorsTranslation-rotationSmall fan-beam

Page 15: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Third Generation

Multiple detectorsTranslation-rotationLarge fan-beam

Page 16: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Fourth Generation

Detector ringSource-rotationLarge fan-beam

Page 17: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Third & Fourth Generations

(From Picker)

(From Siemens)

Page 18: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Simultaneous•Source rotation•Table translation•Data acquisition

Spiral/Helical Scanning

Page 19: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Cone-Beam Geometry

X

Z

Y

Page 20: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Scanning modes

• First generationOne detector, translation-rotationParallel-beam

• Second generationMultiple detectors, translation-rotationSmall fan-beam

• Third generationMultiple detectors, rotation-rotationLarge fan-beam

Page 21: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Scanning modes

• Fourth generationDetector ring, source-rotationLarge fan-beam

• Spiral/Helical scanning, cone-beam geometry

Page 22: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Computed Tomography Principles

1. Projection measurement

2. Scanning modes

3. Scanner systems

4. Image reconstruction

Page 23: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Spiral CT Scanner

Gantry

Data acquisitionsystem

Detectors

Storage units:Tapes, disks

Display

Controlconsole

Computer

Parallelprocessor

Table Recording

Source

Network

Page 24: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Filter

Data Acquisition System (DAS)

Source Detector

Pre-Collimator Post-Collimator

Patient

Scattering

Page 25: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Data Acquisition System (DAS)

X-ray Tube

Detectors

CT Gantry(From Siemens)

Filter

Source

Detector

Page 26: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Spiral CT Scanner

• GantryData acquisition system

• Table• Computer

Parallel processors• Control console• Storage units

Tapes, disks• Recording device• Network interfaceX-ray generatorHeat exchanger

(From Elscint)

Page 27: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

E-Beam CT Scanner

• Speed: 50, 100 ms• Thickness: 1.5, 3, 6, 10 mm• ECG trigger cardiac images

(From Imatron)

Page 28: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Computed Tomography Principles

1. Projection measurement

2. Scanning modes

3. Scanner systems

4. Image reconstruction

Page 29: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Computed Tomography

P(t) f(x,y)P(t)

f(x,y)

t

y

x

X-rays

Computed tomography (CT):Image reconstruction fromprojections

Page 30: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Reconstruction Idea

4

6

3

7

42

31

43

21

Page 31: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Algebraic Reconstruction Technique(ART)

Update a guessbased on

data differences

Guess 1

Guess 0

Guess 2

Error

Error

Page 32: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Fourier Transformation

dudvevuFvuFFyxf

dxdyeyxfyxfFvuF

vyuxj

vyuxj

)(21

)(2

),(),(),(

),(),(),(

FourierTransform

f(x,y) F(u,v)

ImageSpace

FourierSpace

Page 33: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Fourier Slice Theorem

v

u

F(u,v)

P(t)

f(x,y)

t

y

x

X-rays

F[P(t)]

Page 34: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

From Projections to Image

y

x

v

u

F-1[F(u,v)]

f(x,y) P(t) F(u,v)

Page 35: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Filtered Backprojection

f(x,y) f(x,y)

P(t) P’(t)

1) Convolve projections with a filter2) Backproject filtered projections

Page 36: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Example: Projection

SinogramIdeal Image

Projection

Projection

Page 37: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Example: Backprojection

Projection

Page 38: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Example: Backprojection

Sinogram Backprojected Image

Page 39: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Example: Filtering

Filtered SinogramSinogram

Page 40: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

Example: Filtered Backprojection

Filtered Sinogram Reconstructed Image

Page 41: Computed Tomography Principles Ge Wang, Ph.D. Department of Radiology University of Iowa Iowa City, Iowa 52242, USA.

References

T. S. Curry III, J. E. Dowdey, R. C. Murry Jr. Christensen’s physics of diagnostic Radiology (4th edition), Lea & Febiger (for residents)

G. Wang, M. W. Vannier: Computerized tomography. Encyclopedia of Electrical and Electronics Engineering, edited by Webster JG, to be published by John Wiley & Sons (for engineers)

http://dolphin.radiology.uiowa.edu/ge (on-line slides & handouts in the Teaching section)