Cognitive Behavior Therapy in the Treatment of Irritable Bowel Syndrome

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Title: Authors: Affiliation: Source: Publisher: Keywords: Abstract: Document Type: ISSN: DOI: Accession Number: Copyright: Database: Record: 1 Peripherally Acting Therapies for the Treatment of Irritable Bowel Syndrome Richard J. Saad Division of Gastroenterology, University of Michigan Health System, 3912 Taubman Center, 1500 East Medical Center Drive, SPC 5362, Ann Arbor, MI 48109, USA In Irritable Bowel Syndrome, Gastroenterology Clinics of North America 40(1):163-182 Elsevier Inc. Irritable bowel syndrome Lubiprostone Alosetron Serotonergic agents Gut-acting therapies are common therapies for irritable bowel syndrome (IBS). Most of these peripheral acting agents are primarily targeted at individual symptoms. The evidence supporting the use of these agents in IBS is largely anecdotal. Serotonergic agents and the chloride channel activator lubiprostone have shown efficacy in treating symptoms of IBS. The clinical evidence supporting the use of these agents is based on data from high-quality clinical trials. The use of serotonergic agents for IBS in the United States is limited to the 5-hydroxytryptamine-3 antagonist alosetron in the treatment of women with severe IBS with diarrhea refractory to traditional therapy. Review Article 0889-8553 10.1016/j.gtc.2010.12.008 S0889855310001329 Copyright © 2011 Elsevier Inc. All rights reserved. ScienceDirect EBSCOhost Discovery Service http://ehis.ebscohost.com/eds/delivery?sid=7e2ec369-d5c5-4f7e-a19a-... 1 of 1 03-08-2013 14:31

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Transcript of Cognitive Behavior Therapy in the Treatment of Irritable Bowel Syndrome

  • Title:

    Authors:Affiliation:

    Source:

    Publisher:Keywords:

    Abstract:

    Document Type:ISSN:DOI:

    Accession Number:Copyright:Database:

    Record: 1Peripherally Acting Therapies for the Treatment of Irritable BowelSyndrome

    Richard J. Saad

    Division of Gastroenterology, University of Michigan Health System,3912 Taubman Center, 1500 East Medical Center Drive, SPC 5362,Ann Arbor, MI 48109, USA

    In Irritable Bowel Syndrome, Gastroenterology Clinics of NorthAmerica 40(1):163-182

    Elsevier Inc.

    Irritable bowel syndromeLubiprostoneAlosetronSerotonergic agents

    Gut-acting therapies are common therapies for irritable bowelsyndrome (IBS). Most of these peripheral acting agents are primarilytargeted at individual symptoms. The evidence supporting the use ofthese agents in IBS is largely anecdotal. Serotonergic agents and thechloride channel activator lubiprostone have shown efficacy intreating symptoms of IBS. The clinical evidence supporting the use ofthese agents is based on data from high-quality clinical trials. The useof serotonergic agents for IBS in the United States is limited to the5-hydroxytryptamine-3 antagonist alosetron in the treatmentof women with severe IBS with diarrhea refractory to traditionaltherapy.

    Review Article

    0889-8553

    10.1016/j.gtc.2010.12.008

    S0889855310001329

    Copyright 2011 Elsevier Inc. All rights reserved.

    ScienceDirect

    EBSCOhost Discovery Service http://ehis.ebscohost.com/eds/delivery?sid=7e2ec369-d5c5-4f7e-a19a-...

    1 of 1 03-08-2013 14:31


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