Coats dse
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Transcript of Coats dse
![Page 1: Coats dse](https://reader036.fdocuments.net/reader036/viewer/2022071814/55a74afd1a28ab57248b46e1/html5/thumbnails/1.jpg)
COAT’S DISEASE
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COAT’S Disease
• Presence of
– vascular dilatations (retinal telangiectasia),
• Ectatic arterioles,
• Microaneurysms,
• Venous dilations (phlebectasias), and
• Fusiform capillary dilatations,
– frequently associated with exudative retinal detachment.
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• Retinal Capillary nonperfusion• Neovascularization is distinctly UNUSUAL • Vessels are incompetent
– Leakage of serum and other blood components and accumulate under the retina
– Any portion of the peripheral retina and macula can be involved
• Variation is wide – Mild retinal vascular abnormalities– Minimal exudations– Extensive areas of telangectasias associated with massive
leakage and ERD (children with coat’s dse)
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"Light bulb” Aneurysms
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Histopathology of Coat’s Disease
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COATS• MALE (85%)• YOUNG
– Faster Progression in children younger than 4 yo– Massive Exudation with ERD apposing the lens
• DDX of leukocoria? ----– Retinoblastoma– Retinoma– Retinal Dysplasia – Coloboma– Myelinated Nerve Fiber layers – Astrocytic hamartroma– Granuloma – PFV– TRAUMA– Endophthalnmitis– ROP– FEVR
• UNILATERAL• Gradual Progression w increasing Exudation
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COATS in ADULTS
• Patients with peripheral areas of leakage typically present with lipid deposition in otherwise angiographically normal macula.
• Similar findings in adults represent LATE DECOMPENSATION of preexisting vascular anomalies– DDX
• ROP
• Dominant (Familial) Exudative Vitreoretinopathy
• Capillary Hemangioma ( VonHL)