PUBLICATIONS

1987

1. Kok FJ, Duijn CM van, Hofman A, Vermeeren R, Bruijn AM de, Valkenburg HA. Micronutrients and the risk of lung cancer (Letter). N Engl J Med 1987;316:1416.

1988

2. Duijn CM van, Steensel Moll HA van, Does-van der Berg A van der, Wering ER van, Zanen GE van, Valkenburg HA, Rammeloo JA. Infant feeding and childhood cancer (Letter). Lancet 1988;ii:796 7.

3. Hofman A, Duijn CM van, Rocca WA. Is Alzheimer's disease distinct from normal ageing? (Letter). Lancet 1988;ii:226 7.

4. Kok FJ, Duijn CM van, Hofman A, Wolf FA de, Valkenburg HA. Serum copper and zinc predict death from cancer and cardiovascular disease. Am J Epidemiol 1988;128:352 9.

1989

5. Hofman A, Schulte W, Tanja TA, Duijn CM van, Haaxma R, Lameris AJ, Otten VM, Saan RJ. History of dementia and Parkinson's disease in 1st degree relatives of patients with Alzheimer's disease. Neurology 1989;39:1589 92.

1990

6. Duijn CM van, Hofman A, Nagelkerken L. Serum levels of interleukin 6 are not elevated in patients with Alzheimer's disease. Neurosci Lett 1990;108:350 4.

7. Hofman A, Duijn CM van, Schulte W, Tanja TA, Haaxma R, Lameris AJ, Saan RJ. Is parental age related to the risk of Alzheimer's disease? Br J Psychiatry 1990;157:273 5.

1991

8. Boerrigter METI, Duijn CM van, Mullaart E, Eikelenboom P, Togt CMA van der, Knook DL, Hofman A, Vijg J. Decreased DNA repair capacity in familial, but not in sporadic Alzheimer's disease. Neurobiol Aging 1991;12:367 70.

9. Breteler MMB, Duijn CM van, Chandra V, Fratiglioni L, Graves AB, Heyman A, Jorm AF, Kokmen E, Kondo K, Mortimer JA, Rocca WA, Shalat SL, Soininen H, Hofman A. Medical history and Alzheimer's disease: A collaborative re analysis of 11 case control studies. Int J Epidemiol 1991;20:S36 S42.

10. Duijn CM van, Hofman A. Relation between nicotine intake and Alzheimer's disease? BMJ 1991;302:1491 4.

11. Duijn CM van, Hendriks L, Cruts M, Hardy JA, Hofman A, Broeckhoven C van. Amyloid precursor protein gene mutation in early-onset Alzheimer's disease (Letter). Lancet 1991;337:978.

12. Duijn CM van, Broeckhoven C van, Hardy JA, Goate AM, Rossor MN, Vandenberghe A, Martin J J, Hofman A, Mullan MJ. Evidence for allelic heterogeneity in familial early onset Alzheimer's disease. Br J Psychiatry 1991;158:471 4.

13. Duijn CM van, Farrer LA, Cupples LA, Hofman A. Risk of dementia in first degree relatives of patients with Alzheimer's disease. In: Iqbal K, McLachlan DRC, Winblad B, Wisniewski HM (eds); Alzheimer's disease: Basic mechanism, diagnosis and therapeutic strategies. John Wiley & Sons, Chichester, 1991, 423 6.

14. Duijn CM van, Hofman A (eds). Prologue. Int J Epidemiol 1991;20:S3.

15. Duijn CM van, Stijnen T, Hofman A. Risk factors for Alzheimer's disease: Overview of the EURODEM collaborative re analysis of case control studies. Int J Epidemiol 1991;20:S4 S12.

16. Duijn CM van, Clayton D, Chandra V, Fratiglioni L, Graves AB, Heyman A, Jorm AF, Kokmen E, Kondo K, Mortimer JA, Rocca WA, Shalat SL, Soininen H, Hofman A. Familial aggregation of Alzheimer's disease and related disorders: A collaborative re analysis of case control studies. Int J Epidemiol 1991;20:S13 S20.

17. Graves AB, Duijn CM van, Chandra V, Fratiglioni L, Heyman A, Jorm AF, Kokmen E, Kondo K, Mortimer JA, Rocca WA, Shalat SL, Soininen H, Hofman A. Alcohol and tobacco consumption as risk factors for Alzheimer's disease: A collaborative re analysis of case control studies. Int J Epidemiol 1991;20:S48 S57.

18. Graves AB, Duijn CM van, Chandra V, Fratiglioni L, Heyman A, Jorm AF, Kokmen E, Kondo K, Mortimer JA, Rocca WA, Shalat SL, Soininen H, Hofman A. Occupational exposures to solvents and lead as risk factors for Alzheimer's disease: A collaborative re analysis of case control studies. Int J Epidemiol 1991;20:S58 S61.

19. Jorm AF, Duijn CM van, Chandra V, Fratiglioni L, Graves AB, Heyman A, Kokmen E, Kondo K, Mortimer JA, Rocca WA, Shalat SL, Soininen H, Hofman A. Psychiatric history and related exposures as risk factors for Alzheimer's disease: A collaborative re analysis of case control studies. Int J Epidemiol 1991;20:S43 S47.

20. Mortimer JA, Duijn CM van, Chandra V, Fratiglioni L, Graves AB, Heyman A, Jorm AF, Kokmen E, Kondo K, Rocca WA, Shalat SL, Soininen H, Hofman A. Head trauma as a risk factor for Alzheimer's disease: A collaborative re analysis of case control studies. Int J Epidemiol 1991;20:S28 S35.

21. Nijhuis E, Duijn CM van, Witteman C, Hofman A, Rozing J, Nagelkerken L. T cell reactivity in patients with Alzheimer's disease. In: Iqbal K, McLachlan DRC, Winblad B, Wisniewski HM (eds); Alzheimer's disease: Basic mechanism, diagnosis and therapeutic strategies. John Wiley & Sons, Chichester, 1991,581 6.

22. Rocca WA, Duijn CM van, Clayton D, Chandra V, Fratiglioni L, Graves AB, Heyman A, Jorm AF, Kokmen E, Kondo K, Mortimer JA, Shalat SL, Soininen H, Hofman A. Maternal age as a risk factor of Alzheimer's disease: A collaborative re analysis of case control studies. Int J Epidemiol 1991;20:S21 S27.

1992

23. Breteler MMB, Claus J, Duijn CM van, Launer LJ, Hofman A. Epidemiology of Alzheimer's disease and dementia. Epidemiol Rev 1992;14:59-82.

24. Clayton D, Duijn CM van. Case control studies of environmental influences in diseases with genetic determinants (Letter). Am J Epidemiol 1992;135:1315-7.

25. Duijn CM van, Hofman A. Risk factors for Alzheimer's disease: The EURODEM collaborative analysis of case control studies. Neuroepidemiol 1992;11(suppl 1):106-13.

26. Duijn CM van, Tanja TA, Haaxma R, Schulte W, Saan RJ, Lameris AJ, Antonides Hendriks G, Hofman A. Head trauma and the risk of Alzheimer's disease. Am J Epidemiol 1992;135:775-83.

27. Hendriks L, Duijn CM van, Cras P, Cruts M, Hul W van, Harskamp F van, Warren A, McInnis MG, Antonarakis SE, Martin J-J, Hofman A, Broeckhoven C van. Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene. Nat Genet 1992;1:218-21.

28. Leeuwen FE van, Duijn CM van, Camps MH, Kempers BA, Mentjens MF, Mulder HB, Schouten EG, Zwijsen RM, Rookus MA. Agreement between oral contraceptive users and prescribers: implications for case control studies. Contraception 1992;45:399 408.

29. Steensel Moll HA van, Duijn CM van, Valkenburg HA, Zanen GE van. Predominance of hospital deliveries among children with acute lymphocytic leukemia: speculations about neonatal exposure to fluorescent light. Cancer Causes Control 1992;3:389 90.

1993

30. Duijn CM van, Farrer LA, Cupples LA, Hofman A. Genetic transmission of Alzheimer disease among families in a Dutch population-based study. J Med Genet 1993;30:640-6.

31. Duijn CM van, Hendriks L, Farrer LA, Backhovens H, Cruts M, Wehnert A, Hofman A, Broeckhoven C van. Linkage to chromosome 14, 19 and 21 in families derived from a population-based study of Alzheimer's disease. Am J Hum Genet 1993;53:871.

32. Duijn CM van, Samson WN, Hop WCJ, Hofman A. Family history and concomitant clinical features in early-onset Alzheimer's disease. Genet Epidemiol 1993;10:342.

33. Rao VS, Connor L, Duijn CM van, Growdon JH, Farrer LA. Segregation analysis of Alzheimer's disease shows evidence for dominant transmission, phenocopies and age at onset heterogeneity. Am J Hum Genet 1993;53:846.

34. Duijn CM van. Genetic epidemiology of Alzheimer's disease and Parkinson's disease. In: European Communities Science, Research and Development Report, EUR 14848 EN, 1993.

1994

35. Berberian KM, Duijn CM van, Hoes AW, Valkenburg HA, Hofman A. Alcohol and mortality: results from the EPOZ follow-up study. Eur J Epidemiol 1994;10:587-93.

36. Duijn CM van, Knijff P de, Cruts M, Wehnert A, Havekes LM, Hofman A, Broeckhoven C van. Apolipoprotein E E4 allele in a population-based study of early-onset Alzheimer's disease. Nat Genet 1994;7:74-8.

37. Duijn CM van, Hendriks L, Farrer LA, Backhovens H, Cruts M, Wehnert A, Hofman A, Broeckhoven C van. A population-based study of familial Alzheimer's disease: linkage to chromosome 14, 19 and 21. Am J Hum Genet 1994;55:714-27.

38. Duijn CM van, Broeckhoven C van. Alzheimer's disease and the family effect (Correspondence). Nat Genet 1994;8:115.

39. Duijn CM van, Clayton D, Chandra V, Fratiglioni L, Graves AB, Heyman A, Jorm AF, Kokmen E, Kondo K, Mortimer JA, Rocca WA, Shalat SL, Soininen H, Hofman A. Interaction between genetic and environmental risk factors for Alzheimer's disease: a re analysis of case control studies. Genet Epidemiol 1994;11:539-51.

40. Duijn CM van, Steensel Moll HA van, Coebergh JWW, Zanen GE van. Risk factors for childhood acute non-lymphocytic leukaemia: an association to maternal alcohol consumption during pregnancy? Cancer Epidemiol Biomarkers Prev 1994;3:457-60.

41. Haan J, Broeckhoven C van, Duijn CM van, Voorhoeve E, Harskamp F van, Swieten JC van, Maat-Schieman MLC, Roos RAC, Bakker E. The apolipoprotein E 4 allele does not influence the clinical expression of the amyloid precursor protein-gene codon 693 or 692 mutations. Ann Neurol 1994;36:434-7.

42. Nijhuis E, Hinloopen B, Duijn CM van, Hofman A, Rozing J, Nagelkerken L. Decreased sensitivity to dexamethasone in lymphocytes from patients with Alzheimer's disease. Clin Immunol Immunopathol 1994;73:45-52.

43. Rao VS, Duijn CM van, Connor-Lacke L, Cupples LA, Growdon JH, Farrer LA. Multiple etiology for Alzheimer disease revealed by segregation analysis. Am J Hum Genet 1994;55:991-1000.

1995

44. Bromberg JEC, Rinkel GJE, Algra A, Duijn CM van, Greebe P, Ramos LMP, Gijn J van. Familial subarachnoid haemorrhage: distinctive features and pattern of inheritance. Ann Neurol 1995;38:929-34.

45. Bromberg JEC, Rinkel GJE, Algra A, Greebe P, Duijn CM van, Hasan D, Limburg M, Berg HWM ter, Wijdicks EFM, Gijn J van. Subarachnoid haemorrhage in first and second degree relatives of patients with subarachnoid haemorrhage. BMJ 1995;311:288-289.

46. Commenges D, Jacqmin H, Letenneur L, Duijn CM van. Score test for familial aggregation in probands studies: application to Alzheimer's disease. Biometrics 1995;51:542-51.

47. Cruts M, Backhovens H, Gassen G van, Theuns J, Wang S-Y, Wehnert A, Duijn CM van, Nylander P-O, Hofman A, Adolfson R, Martin J-J, Broeckhoven C van. Mapping and sequencing the chromosome 14q24.3 dihydrolipoyl succinyltransferase (DLST) gene in patients with early-onset Alzheimer's disease. Neurosci Lett 1995;199:73-7.

48. Duijn CM van, Knijff P de, Cruts M, Wehnert A, Voecht J de, Havekes LM, Hofman A, Broeckhoven C van. The apolipoprotein E gene and the risk of early-onset Alzheimer's disease. In: Iqbal K, Mortimer JA, Winblad B, Wisniewski HM (eds); Research Advances in Alzheimer's disease and related disorders. John Wiley & Sons, Chichester, 1995, 97-101.

49. Duijn CM van, Knijff P de, Wehnert A, Voecht J de, Bronzova JB, Havekes LM, Hofman A, Broeckhoven C van. The apolipoprotein E ε2 allele is associated with an increased risk of early-onset Alzheimer's disease and a reduced survival. Ann Neurol 1995;37:605-10.

50. Duijn CM van, Broeckhoven C van, Knijff P de, Cruts M, Wehnert A, Havekes LM, Hofman A. Smoking and Apolipoprotein E ε4 allele and the risk of early-onset Alzheimer's disease. BMJ 1995;310:627-31.

51. Farrer LA, Cupples A, Duijn CM van, Kurz A, Zimmer R, Mulller U, Green RC, Clarke V, Shoffner J, Wallace DC, Chui H, Flanagan SD, Duara R, St George Hyslop P, Auerbach SA, Volicer L, Well JM, Broeckhoven C van, Growdon JH, Haines JL. APOE genotype in patients with Alzheimer's disease: implications for the risk of dementia among relatives. Ann Neurol 1995;38:797-808.

52. Farrer LA, Cupples LA, Duijn CM van, Connor-Lacke L, Kiely DK, Growdon JH. Rate of progression of Alzheimer disease is associated with genetic risk. Arch Neurol 1995;52:918-23.

53. Gool WA van, Evenhuis HM, Duijn CM van, for the Study Group Down Syndrome & Ageing. A case-control study of apolipoprotein E genotypes in Alzheimer's disease associated with Down syndrome. Ann Neurol 1995;38:225-30.

54. Stevens M, Swieten JC van, Duijn CM van, Tibben A, Niermeijer MF. De fronto-temporale dementie: onderzoek naar het familiair voorkomen. Ned Tijdschr Geneesk 1995;139:871-5.

1996

55. Bronzova J, Duijn CM van, Havekes LM, Knijff P de, Broeckhoven C van, Hofman A. Apolipoprotein E genotype and concomitant clinical features in early-onset Alzheimer's disease. J Neurol 1996;243:465-8.

56. Duijn CM van, Broeckhoven C van. Re: The apolipoprotein E 2 allele is associated with an increased risk of early-onset Alzheimer's disease and a reduced survival. Ann Neurol 1996;39:415-6.

57. Duijn CM van. Epidemiology of the dementia: recent developments and new approaches. J Neurol Neurosurg Psychiatr 1996;60:478-88.

58. Rao V, Cupples L, Duijn CM van, Kurz A, Green RC, Chui H, Duara R, Auerbach SA, Volicer L, Wells J, Broeckhoven C van, Growdon JH, Haines JL, Farrer LA. Evidence for major gene inheritance of Alzheimer disease in families of patients with and without APOE 4. Am J Hum Genet 1996;59:664-75.

59. Samson WN, Duijn CM van, Hop WCJ, Hofman A. Clinical features and mortality in patients with early-onset Alzheimer's disease. Eur Neur 1996;36:103-6.

60. Slooter A, Breteler MMB, Ott A, Broeckhoven C van, Duijn CM van. APOE genotyping in differential diagnosis of Alzheimer's disease, (Letter). Lancet 1996;348:334.

61. Slooter AJC, Gool WA van, Duijn CM van. De plaats van apolipoproteine-E-genotypering in de differentiaaldiagnostiek van dementie. Ned Tijdschr Geneesk 1996;140:2073-6.

62. Uitterlinden AG, Pols HAP, Burger H, Huang O, Daele PLA van, Duijn CM van, Hofman A, Birkenhager JC, Leeuwen JPTM van. A large-scale population-based study of the association of vitamin D receptor gene polymorphisms with bone mineral density. J Bone Miner Res 1996;11:1241-8.

63. Wientjens DPWM, Davanipour Z, Hofman A, Kondo K, Matthews WB, Will RG, Duijn CM van. Risk factors for Creutzfeldt-Jakob disease: a re-analysis of case-control studies. Neurology 1996;46:1287-91.

1997

64. Duijn CM van. Menopause and the brain. J Psychosom Obstet Gynecol 1997;18:121-5.

65. Farrer LA, Cupples LA, Haines JL, Hyman B, Kukull WA, Mayeux R, Myers RH, Pericak- Vance MA, Risch N, Duijn CM van; for APOE and Alzheimer Disease Meta-analysis Consortium. Effects of age, gender and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. JAMA 1997;278:1349-56.

66. Harskamp F van, Cras P, Hendriks L, Kros JM, Hofman A, Broeckhoven C van, Duijn CM van. A family with early-onset Alzheimer's disease and cerebral haemorrhage due to a mutation (codon 692) in the -amy¬loid precursor protein gene. In: Iqbal K, Mortimer JA, Winblad B, Nishimura T,Wisniewski HM (eds); Alzheimer's disease: Biology, Diagnosis and Therapeutics. John Wiley & Sons, Chichester, 1997:155-9.

67. Heutink P, Stevens M, Rizzu P, Bakker E, Kros JM, Tibben A, Niermeijer MF, Duijn CM van, Oostra BA, Swieten JC van. Hereditary Fronto-Temporal Dementia is linked to chromosome 17q21-q22. A genetic and clinico-pathological study of three Dutch families. Ann Neurol 1997;41:150-9.

68. Hofman A, Ott A, Breteler MMB, Bots ML, Slooter AJC, Harskamp F van, Duijn CM van, Broeckhoven C van, Grobbee DE. Atherosclerosis, apolipoprotein E and the prevalence of dementia and Alzheimer's disease in a population-based study: the Rotterdam Study. Lancet 1997;349:151-4.

69. Meulenbelt I, Bijkerk C, Wildt SCM de, Miedema H, Valkenburg HA, Breedveld FC, Pols HA, Te Koppele J, Sloos VFG, Hofman A, Slagboom PE, Duijn CM van. Investigation of the association of the CRTM and CRTL1 genes with radiological evident osteoarthritis in subjects from the Rotterdam Study. Arthr Rheum 1997;40:1760-5.

70. Murphy GM Jr, Sullivan EV, Gallagher-Thompson D, Thompson LW, Duijn CM van, Forno LS, Ellis WG, Jagust WJ, Yesavage J, Tinklenberg JR. No association between the alpha 1-antichymotrypsin A allele and Alzheimer’s disease. Neurology 1997;48:1313-6.

71. Samren EB, Duijn CM van, Koch S, Hiilesma VK, Klepel H, Bardy AH, Mannegetta B, Deichl AW, Gaily E, Granstrom ML, Meinardi H, Grobbee DE, Hofman A, Lindhout D. Maternal use of anti-epileptic drugs and the risk of major congenital malformations: A Joint European Prospective study on human teratogenesis associated with maternal epilepsy. Epilepsia 1997;38:981-90

72. Slooter AJC, Duijn CM van. Genetic epidemiology of Alzheimer's Disease. Epidemiol Rev 1997;19:107-19.

73. Slooter AJC, Tang MX, Duijn CM van, Stern Y, Ott A, Bell K, Breteler MMB, Broeckhoven C van, Tatemichi TK, Tycko B, Hofman A, Mayeux R. Apolipoprotein E4 increases the risk of dementia with stroke. A population-based investigation. JAMA 1997;277:818-21.

74. Stevens M, Duijn CM van, Knijff P de, Broeckhoven C van, Heutink P, Oostra BA, Niermeijer MF, Swieten JC van. Apolipoprotein E gene and sporadic frontal lobe dementia. Neurology 1997;48:1526-9.

75. Tibben A, Steven M, Wert GMWR de, Niermeijer MF, Duijn CM van, Swieten JC van. Preparing for presymptomatic DNA testing for early onset Alzheimer's disease /cerebral haemorrhage and hereditary Pick disease. J Med Genet 1997;34:63-72.

76. Uitterlinden A, Burger H, Huang Q, Odding E, Duijn CM van, Hofman A, Birkenhager JC, Leeuwen JPTM van, Pols AP. Vitamin D receptor genotype is associated with osteoarthritis. J Clin Invest 1997;100:259-63.

1998

77. Cammen TJM van der, Verschoor CJ, Loon CPM van, Harskamp F van, Koning I de, Schudel WJ, Slooter AJC, Broeckhoven C van, Duijn CM van. Risk of left ventricular dysfunction in patients with probable Alzheimer's disease with APOE*4 allele. J Am Geriatr Soc 1998;46:962-7.

78. Cras P, Harskamp F van, Hendriks L, Ceuterick C, Duijn CM van, Stefanko SZ, Hofman A, Kros JM, Broeckhoven C van, Martin JJ. Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692 Ala => Gly mutation. Acta Neuropathol 1998;96:253-60.

79. Cruts M, Duijn CM van, Backhovens H, Brooke M van den, Wehnert A, Serneels S, Sherrington R, Hutton M, Hardy J, Hyslop PH, Hofman A, Broeckhoven C van. Estimation of the genetic contribution of presenilin-1 and -2 mutations in a population-based study of presenile Alzheimer disease. Hum Mol Genet 1998;7:43-51.

80. Duijn CM van, Delasnerie Laupretre N, Masullo C, Zerr I, Silva R de, Wientjens DPWM, Brandel J-P, Weber T, Bonavita V, Zeidler M, Alperovitch A, Poser S, Granieri E, Hofman A, Will RG. For the EU Collaborative Study Group for CJD. Case-control study of risk factors of Creutzfeldt Jakob disease in Europe during 1993 95. Lancet 1998;351:1081-5.

81. Esch A, Steyerberg EW, Duijn CM van, Offringa M, Derksen-Lubsen G, Steensel-Moll HA. Prediction of febrile seizures in siblings: a practical approach. Eur J Pediatrics 1998;157:340-4.

82. Fahim S, Duijn CM van, Baker FM, Launer L, Breteler MMB, Schudel WJ, Hofman A. A study of familial aggregation of depression, dementia and Parkinson's disease. Eur J Epidemiol 1998;14:233-8.

83. Farrer LA, Duijn CM van, Mayeux R, Haines JL, Kukull WA, Hyman B, Pericak-Vance MA, Risch N. Effects of Age and Ethnicity on the link between APOE 4 and Alzheimer disease. JAMA 1998;279:581-2.

84. Klaver CCW, Assink JJM, Bergen AAB, Duijn CM van. ABCR gene and age-related macular degeneration (Correspondence). Science 1998;279:1107.

85. Klaver CCW, Kliffen M, Duijn CM van, Hofman A, Cruts M, Grobbee DE, Broeckhoven C van, Jong PTVM de. Genetic association of apolipoprotein E with age related macular degeneration. Am J Hum Genet 1998;63:200-6.

86. Klaver CCW, Wolfs RC, Assink JJM, Duijn CM van, Hofman A, Jong PTVM de. Genetic Risk of age-related maculopathy. A population-based familial aggregation study. Arch Opthalmol 1998;116:1646-51.

87. Knijff P de, Duijn CM van. Role of APOE in dementia: a critical reappraisal. Haemostasis 1998;28:195-201.

88. Meulenbelt I, Bijkerk C, Miedema H, Breedveld FC, Hofman A, Valkenburg HA, Pols HAP Slagboom PE, Duijn CM van. The IGF-1 gene and radiological osteoarthritis (ROA) in a population-based cohort study (Rotterdam Study). Ann Rheum Dis 1998;57:371-4.

89. Ott A, Slooter AJC, Hofman A, Harskamp F van, Witteman JCM, Broeckhoven C van, Duijn CM van, Breteler MMB. Smoking and the risk of dementia and Alzheimer's disease in a population based cohort study: the Rotterdam study. Lancet 1998;351:1840-3.

90. Roks G, Cruts M, Bullido MJ, Backhovens H, Artiga MJ, Hofman A, Valdivieso F, Broeckhoven C van, Duijn CM van. The –491 A/T polymorphism in the regulatory region of the apolipoprotein E gene and early-onset Alzheimer’s disease. Neurosci Lett 1998;258:65-8.

91. Slooter AJC, Cruts M, Kalmijn S, Hofman A, Breteler MMB, Broeckhoven C van, Duijn CM van. Risk estimates of dementia by apolipoprotein E genotype from a population-based incidence study: the Rotterdam Study. Arch Neurol 1998;55:964-8.

92. Slooter AJC, Duijn CM van, Bots ML, Ott A, Breteler MMB, Voecht J de, Wehnert A, Knijff P de, Havekes LM, Grobbee DE, Broeckhoven C van, Hofman A. Apolipoprotein E genotype, atherosclerosis, and cognitive decline: the Rotterdam study. J Neural Transm 1998;S53:17-29.

93. Slooter AJC, Knijff P de, Hofman A, Cruts M, Breteler MMB, Broeckhoven C van, Havekes LM, Duijn CM van. Serum apolipoprotein E level is not increased in Alzheimer's disease. Neurosci Lett 1998;248:21-4.

94. Stevens M, Duijn CM van, Kamphorst W, Knijff P de, Heutink P, Gool WA van, Scheltens Ph, Ravid R, Oostra BA, Niermeijer MF, Swieten JC van. Familial aggregation in fronto-temporal dementia. Neurology 1998;50:1541-5.

95. Will RG, Alperovitch A, Poser S, Pocchiari M, Hofman A, Mitrova E, Silva R de, D'Alesandro M, Brandel J-P, Zerr I, Duijn CM van. Creutzfeldt Jakob disease in Europe 1993 1995. Descriptive epidemiology. For the EU Collaborative Study Group for CJD. Ann Neurol 1998;43:763-7.

96. Wolfs RC, Klaver CCW, Ramrattan R, Duijn CM van, Hofman A, Jong PTVM de. Genetic Risk of primary open-angle glaucoma. A population-based familial aggregation study. Arch Opthalmol 1998;116:1640-5.

1999

97. Alperovitch A, Zerr I, Pocchiari M, Mitrova E, Cuesta J de Pedro, Hegyi I, Collins S, Kretzschmar H, Duijn CM van, Will RG. Codon 129 prion protein genotype and sporadic Creutzfeldt Jakob disease. Lancet 1999;353:1673-4.

98. Bijkerk C, Houwing-Duistermaat JJ, Valkenburg HA, Meulenbelt I, Hofman A, Breedveld FC, Pols HAP, Duijn CM van, Slagboom PE. Heritabilities of radiologic OA in peripheral joins and of disc degeneration of the spine. Arthr Rheum 1999;42:1729-35.

99. Dermaut B, Cruts M, Slooter AJC, Gestel S van, Jonghe C de, Vanderstichele H, Vanmechelen E, Breteler MMB, Hofman A, Duijn CM van, Broeckhoven C van. The glu318gly mutation in presenilin 1 is not causally related to Alzheimer’s disease. Am J Hum Genet;1999:64:290-2.

100. Duijn CM van. Hormone replacement therapy and Alzheimer’s disease. Maturitas 1999;31:201-5.

101. Duijn CM van, Cruts M, Theuns J, Gassen G van, Backhovens H, Broeck M van den, Wehnert A, Serneels S, Hofman A, Broeckhoven C van. Genetic association of the presenilin-1 regulatory region with early-onset Alzheimer’s disease. Eur J Hum Genet;1999:7:806-7.

102. Harhangi BS, Oostra BA, Heutink P, Duijn CM van, Hofman A, Breteler MMB. N-acetyltransferase 2 polymorphism in Parkinson’s disease. The Rotterdam study. J Neurol Neurosurg Psychiatry 1999;67:518-20.

103. Houlden H, Rizzu P, Stevens M, Knijff P de, Duijn CM van, Swieten JC van, Heutink P, Perez-Tur J, Thomas V, Baker M, Morris H, Rossor M, Jannsen JC, Petersen RC, Dodd P, Dark F, Boeve B, Dickson D, Davies P, Pickering-Brown S, Mann D, Adamson J, Lynch T, Payami H, Poorkaj P, Bird TD, Schellenberg GD, Chadraverty S, Norton J, Morris FC, Goate A, Hutton M, Hardy J. Apolipoprotein E genotype does not affect the age of onset of dementia in families with define tau mutations. Neurosci Lett 1999;260:193-5.

104. Mehta KM, Ott A, Slooter AJC, Duijn CM van, Hofman A, Breteler MMB. Head trauma with loss of consciousness and risk of dementia and Alzheimer's disease. The Rotterdam Study. Neurology 1999;53:1959-62.

105. Meulenbelt I, Bijkerk C, Wildt SCM de, Miedema HS, Breedveld FC, Pols HAP, Hofman A, Duijn CM van, Slagboom PE. Haplotype analysis of three polymorphisms of the COL2A1 gene and associations with generalised radiological osteoarthritis. An Hum Genet 1999;63:303-400.

106. Rizzu P, Swieten JC van, Joosse M, Hasegawa M, Stevens M, Tibben A, Niermeijer MF, Hillebrand M, Ravid R, Oostra BA, Goedert M, Duijn CM van, Heutink P. High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands. Am J Hum Genet;1999:64:414-21.

107. Roks G, Dermaut B, Heutink P, Julliams A, Backhovens H, Broeck M van den, Serneels S, Hofman A, Broeckhoven C van, Duijn CM van, Cruts M. Mutation screening of the tau gene in patients with early-onset Alzheimer’s disease. Neurosci Lett 1999;277:137-9.

108. Samren EB, Duijn CM van, Christiaens CGML, Hofman A, Lindhout D. Anti-epileptic drug regimens and major congenital abnormalities in the offspring. Ann Neurol 1999: 46:739-46.

109. Slooter AJC, Houwing-Duistermaat JJ, Harskamp F van, Cruts M, Broeckhoven C van, Breteler MMB, Hofman A, Stijnen T, Duijn CM van. Apolipoprotein E genotype and the progression of Alzheimer’s disease: the Rotterdam Study. J Neurol 1999;246:304-8.

110. Slooter AJC, Cruts M, Ott A, Bots ML, Witteman JCM, Hofman A, Broeckhoven C van, Breteler MMB, Duijn CM van. The effect of APOE on dementia is not through atherosclerosis: the Rotterdam Study. Neurology 1999;53:1593-5.

111. Slooter AJC, Bronzova J, Witteman JCM, Hofman A, Broeckhoven C van, Duijn CM van. Estrogen and early-onset Alzheimer’s disease. J Neurol Neurosurg Psychiatry 1999;67:779-81.

112. Stuijvenberg van M, Beijeren E van, Wils NH, Derksen-Lubsen G, Duijn CM van, Moll HA. Characterisitcs of the initial seizure in familial in febrile seizures siblings. Arch Dis Child 1999;80:178-80.

113. Tol J, Roks G, Slooter AJC, Duijn CM van. Genetic and environmental factors in Alzheimer’s disease. Rev Neurol 1999;155:10-6.

114. Tol J, Slooter AJC, Duijn CM van. Genetic Factors in early-onset and late-onset Alzheimer’s disease. In: R Mayeux, Christen Y (eds); Epidemiology of Alzheimer’s disease: from gene to prevention. Springer-Verlag, Berlin Heidelberg New York, 1999, 33-39.

2000

115. Croes EA, Dermaut B, Cammen TJM van der, Broeckhoven C van, Duijn CM van. Genetic testing should not be advocated as a diagnositic tool in familial forms of dementia. Am J Hum Genet 2000;67:1033-5.

116. Gestel S van, Houwing-Duistermaat JJ, Adolfsson R, Duijn CM van, Broeckhoven C van. Power of selective genotyping in genetic association analysis of quantitative traits. Behav Genet 2000;30:141-6.

117. Harhangi BS, Rijk MC de, Duijn CM van, Broeckhoven C van, Hofman A, Breteler MMB. Apolipoprotein E genotype, Parkinson's disease, and dementia in Parkinson's disease: the Rotterdam study. Neurology 2000;54:1272-6.

118. Knittweis JW, McMullen WA, Romas SN, Mayeux R, Slooter AJC, Ruitenberg A, Duijn CM van, Breteler MMB, Liu HC. The effect of apoE on dementia is not through atherosclerosis: the Rotterdam Study. Neurology 2000;54:2353-8.

119. Koster MN, Dermaut B, Munteanu G, Houwing-Duistermaat JJ, Roks G, Tol J, Ott A, Hofman A, Cruts M, Breteler MMB, Duijn CM van, Broeckhoven C van. The alpha-2-macroglobuline gene: a population-based study and meta-analysis. Neurology 2000;55:678-84.

120. Roks G, Harskamp F van, Koning I de, Cruts M, Jonghe C de, Kumar-Singh S, Tibben A, Tanghe H, Niermeijer MF, Hofman A, Swieten JC van, Broeckhoven C van, Duijn CM van. Presentation of amyloidosis in carriers of the codon 692 mutation in the amyloid precursor protein gene (APP692). Brain 2000;123:2130-40.

121. Roks G, Duijn CM van. Genetic Epidemiology of Alzheimer’s disease. In ‘Analysis of Multifactorial Disease’. Eds T Bishop and P Sham. Pages 85-100.

122. Theuns J, Del-Favero J, Dermaut B, Duijn CM van, Backhovens H, Broeck M van der, Serneels S, Corsmit E, Broeckhoven C van, Cruts M. Genetic variability in the regulatory region of presenilin 1 associated with risk for Alzheimer’s disease and variable expression. Hum Mol Genet 2000;9:325-31.

123. Uitterlinden AG, Burger H, Duijn CM van, Huang Q, Hofman A, Birkenhager JC, Leeuwen JPTM van, Pols HAP. Adjacent genes, for collagen type II1 gene and the vitamin D receptor, are associated with separate features of the radiographic osteoarthritis at the knee. Arthr Rheum 2000;43:1456-64.

124. Zerr I, Brandel J-P, Masullo C, Wientjens DPWM, Silva R de, Zeidler M, Granieri E, Sanpaolo S, Duijn CM van, Delasnerie-Laupretre N, Will R, Poser S. European Surveillance on Creutzfeldt-Jakob disease: a case-control study for medical risk factors. J Clin Epidemiol 2000;53:747-54.

2001

125. Beck JA, Mead S, Campbell TA, Dickinson A, Wientjens DPWM, Croes EA, Duijn CM van, Collinge J.Two-octapeptide repeat deletion of the prion protein gene associated with a rapidly progressive dementia. Neurology 2001;2:354-6.

126. Cataldo A, Rebeck GW, Ghetri B, Hulette C, Lippa C, Broeckhoven C van, Duijn CM van, Cras P, Bogdanovic N, Bird T, Peterhoff C, Nixon R. Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders. Ann Neurol 2001;50:661-5.

127. Croes EA, Jansen GH, Lemstra AW, Frijns CJM, Gool WA van, Duijn CM van. The first two patients with dura mater associated Creutzfeldt-Jakob disease in the Netherlands. J Neurol 2001;248:877-80.

128. Cruts M, Dermaut B, Rademakers R, Roks G, Broeck M van den, Munteanu G, Duijn CM van, Broeckhoven C van. Amyloid beta secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease. Neurosci Lett 2001;313:105-7.

129. Dermaut B, Roks G, Theuns J, Rademakers R, Houwing-Duistermaat JJ, Serneels S, Hofman B, Breteler MMB, Cruts M, Broekchoven C van, Duijn CM van. Variable expression of presenilin 1 is not a major determinant of risk for late-onset Alzheimer’s Disease. J Neurol 2001;248:935-9

130. Duijn CM van, Dekker MCJ, Bonifati V, Galjaard RJ, Houwing-Duistermaat JJ, Snijders PJLM, Testers L, Breedveld GJ, Horstink M, Sandkuijl LA, Swieten JC van, Oostra BA, Heutink P. PARK7, a novel locus for autosomal recessive early-onset parkinsonism on chromosome 1p36. Am J Hum Genet 2001;69:629-34.

131. Everbroeck B van, Croes EA, Pals P, Dermaut B, Jansen G, Duijn CM van, Cruts M, BroeckhovenC van, Martin J-J, Cras P. Influence of the prion protein and the apolipoprotein E genotype on the Creutzfeldt-jakob Disease phenotype. Neurosci Lett 313 2001;69-72.

132. The EUROCJD Group. Genetic epidemiology of Creutzfeldt-Jakob disease in Europe. Rev Neurol 2001;157:6-7.

133. Geerlings MI, Ruitenberg A, Witteman JC, Swieten JC van, Hofman A, Duijn CM van, Breteler MMB, Launer LJ.Reproductive period and risk of dementia in postmenopausal women. JAMA 2001;285:1475-81.

134. Harhangi BS, Oostra BA, Heutink P, Duijn CM van, Hofman A, Breteler MMB. CYP2D6 polymorphism in Parkinson’s disease: The Rotterdam Study. Mov Disord 2001;16:290-3.

135. Jong PT de, Bergen AA, Klaver CC, Duijn CM van, Assink JM. Age-related maculopathy: its genetic basis. Eye 2001;15:396-400.

136. Kramers C, Danilov SM, Deinum J, Balvasnikova IV, Scharenborg N, Looman M, Boomsma F, Keijzer MB de, Duijn CM van, Martin S, Soubrier F, Adema GJ. Point mutation in the stalk of angiotensin-converting enzyme causes a dramatic increase in serum angiotensin-converting enzyme but no cardiovascular disease. Circulation 2001;104:1236-40.

137. Njajou OT, Vaessen N, Joosse M, Berghuis B, Dongen JWF van, Breuning MH, Snijders PJLM, Rutten WPF, Sandkuijl LA, Oostra BA, Duijn CM van, Heutink P. A mutation in SLC11A3 gene is associated with autosomal dominant hemochromatosis. Nat Genet 2001;28:214-15.

138. Osborne RH, Houben MPWA, Tijssen CC, Coebergh JWW, Duijn CM van. The genetic epidemiology of glioma. Neurology 2001;57:1751-55.

139. Roks G, Cruts M, Slooter AJC, Dermaut B, Hofman A, Broeckhoven C van, Duijn CM van. The Cystatin C polymorphism is not associated with early-onset Alzheimer's disease. Neurology 2001;57:366-7.

140. Schmidt H, Fazekas F, Kostner GM, Duijn CM van, Gradert A, Schmidt R. Angiotensinogen Gene Promoter Haplotype and Microangiopathy-Related Cerebral Damage: Results of the Austrian Stroke Prevention Study. Stroke 2001;32:405-12.

141. Sleegers K, Duijn CM van. Alzheimers’s Disease: Genes, pathogenesis and risk prediction. Community Genet 2001;4:197-203.

142. Slooter AJC, M Cruts, A Hofman, Broeckhoven C van, Duijn CM van. Apoplipoprotein E and longevity: the Rotterdam study. J Am Geriatr Soc 2001;49:1-2.

143. Slooter AJC, Bots ML, Havekes LM, Iglesias del Sol A, Cruts M, Grobbee DE, Hofman A, Broeckhoven C van, Witteman JCM, Duijn CM van. Apolipoprotein E and Carotid Artery Atherosclerosis. The Rotterdam Study. Stroke 2001;32:1947-52.

144. Theuns J, Feuk L, Dermaut B, Del-Favero J, Roks G, Bossche D van den, Corsmit E, Broeck van den, Duijn CM van, Cruts M, Brookes A, Broeckhoven C van.The TNFRSF6 gene is not implicated in familial early-onset Alzheimer’s disease. Hum Genet 2001;108:552-3.

145. Uitterlinden AG, Weel AEAM, Burger H, Yue F, Duijn CM van, Hofman A, Leeuwen PTM van, Pols HAP. Interaction between the vitamin D receptor gene and collagen type I alpha1 gene in susceptibility for fracture. J Bone Miner Res 2001;16:379-85.

146. Vaessen N, Heuting P, Janssen J, Witteman JCM, Testers L, Hofman A, Oostra BA, Lamberts SWJ, Pols HAP, Duijn CM van. Association between a polymorphism in the gene for insulin-like growth factor-I, diabetes and myocardial infarction. Diabetes 2001;50:637-42.

147. Vaessen N, Duijn CM van. Opportunities for population-based studies of complex genetic disorders after the human genome project. Epidemiology 2001;12:360-4.

148. Veld BA in ‘t, Ruitenberg A, Hofman A, Launer LJ, Duijn CM van, Stijnen Th, Breteler MMB, Stricker BHCh. Nonsteroidal anti-inflammatory drugs and the risk of Alzheimer’s disease. New Engl J Med 2001;345:1515-1521.

2002

149. Arends N, Johnston L, Hokken-Koelega A, Duijn CM van, Ridder M de, Sa Vage M, Clark A. Polymorphism in the IGF-I gene: Clinical Relevance for short children born small for gestational age (SGA). J Clin Endocrinol Metab 2002;87:2720-4.

150. Beer F de, Stalenhoef AF, Hoogerbrugge N, Kastelein JJ, Gevers Leuven JA, Duijn CM van, Havekes LM, Smelt AH. Expression of type III hyperlipoproteinemia in apolipoprotein E2 (Arg158--> Cys) homozygotes is associated with hyperinsulinemia.Arterioscler Thromb Vasc Biol 2002;22:294-9.

151. Bertoli Avella AM, Marcheco Teruel B, Llibre Rodriguez JJ, Gomez Viera N, Borrajero Martinez I, Severijnen EA, Joosse M, Duijn CM van, Heredero Baute L, Heutink P. A novel presenilin 1 mutation (L174M) in a large Cuban family with early onset Alzheimer disease. Neurogenetics 2002;4:97-104.

152. Bonifati V, Breedveld GJ, Squitieri F, Vanacore N, Brustenghi P, Harhangi BS, Montagna P, Canella, Fabbrini CG, Rizzu P, Duijn CM van, Oostra BA, Meco G, Heutink P. Localization of autosomal recessive early-onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset. Ann Neurol 2002;51:253-6.

153. Bonifati V, Dekker MC, Vanacore N, Fabbrini G, Squitieri F, Marconi R, Antonini A, Brustenghi P, Dalla Libera A, Mari M de, Stocchi F, Montagna P, Gallai V, Rizzu P, Swieten JC van, Oostra B, Duijn CM van, Meco G, Heutink P. Autosomal recessive early onset

parkinsonism is linked to three loci: PARK 2, PARK 6 and PARK7. Neurol Sci 2002;23:59-60

154. Budka H, Dormont D, Kretzschmar H, Pocchiari M, Duijn CM van. BSE and variant Creutzfeldt-Jakob disease: never say never. Acta Neuropathol 2002;103:627-8.

155. Chumakov I, Blumenfeld M, Guerassimenko O, Cavarec L, Palicio M, Abderrahim H, Bougueleret L, Barry C, Tanaka H, La Rosa P, Puech A, Tahri N, Cohen-Akenine A, Delabrosse S, Lissarrague S, Picard FP, Maurice K, Essioux L, Millasseau P, Grel P, Debailleul V, Simon AM, Caterina D, Dufaure I, Malekzadeh K, Belova M, Luan JJ, Bouillot M, Sambucy JL, Primas G, Saumier M, Boubkiri N, Martin-Saumier S, Nasroune M, Peixoto H, Delaye A, Pinchot V, Bastucci M, Guillou S, Chevillon M, Sainz-Fuertes R, Meguenni S, Aurich-Costa J, Cherif D, Gimalac A, Duijn CM van, Gauvreau D, Ouelette G, Fortier I, Realson J, Sherbatich T, Riazanskaia N, Rogaev E, Raeymaekers P, Aerssens J, Konings F, Luyten W, Macciardi F, Sham PC, Straub RE, Weinberger DR, Cohen N, Cohen D. Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. Proc Natl Acad Sci 2002;99:13675-80

156. Croes EA, Cammen TJ van der, Sleegers K, Duijn CM van. From gene to disease; presenilins and Alzheimer disease. Ned Tijdschr Geneeskd 2002;146:494-5.

157. Croes EA, Duijn CM van, Gool WA van, Jansen GH. Ziekte van Creutzfeld-Jakob: diagnostiek, incidentie, preventie en behandeling. Ned Tijdschr Geneeskd 2002;146:750-4.

158. Croes EA, Roks G, Jansen GH, Nijssen PC, Duijn CM van. Creutzfeldt-Jakob disease 38 years after diagnostic use of human growth hormone. J Neurol Neurosurg Psychiatry 2002;72:792-3.

159. Dermaut B, Theuns J, Sleegers K, Hasegawa H, Broeck M van den, Vennekens K, Corsmit E, St George-Hyslop P, Cruts M, Duijn CM van, Broeckhoven C van. The gene encoding nicastrin, a major gamma-secretase component modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample. Am J Hum Genet 2002;70:1568-74.

160. Gestel S van, Forsgren T, Claes T, Del-Favero J, Duijn CM van, Sluijs S, Nilsson LG, Aldofsson R, Broeckhoven C van. Epistatic effect of genes from the dopamine and serotonin systems on the temperament straits of Novelty Seeking and Harm Avoidance. Mol Psychiatry 2002;7:448-50.

161. Heijer T den, Oudkerk M, Launer LJ, Duijn CM van, Hofman A, Breteler MMB. Hippocampal, amygdalar, and global brain atrophy in different apolipoprotein E genotypes. Neurology 2002;59:746-8.

162. Hottenga JJ, Houwing-Duistermaat JJ, Duijn CM van. Unintentional population stratification in genetic case-control studies. Ned Tijdschr Geneeskd 2002;146:17-22.

163. Houben MPWA, Tijssen CC, Duijn CM van, Coebergh JWW. Genetic and Epidemiological Strategies in the Study of Glioma Etiology. South West Cancer News 2002;11:9-10.

164. Hulsman CAA, Jong PTVM de, Lettink M, Duijn CM van, Hofman A, Bergen AAB. Myocilin mutations in a population-based sample of cases with open-angle glaucoma: the Rotterdam Study. Graefe’s Arch Clin Exp Ophthalmol 2002;240:468-74.

165. Hulsman CA, Houwing-Duistermaat JJ, Duijn CM van, Wolfs R, Borger PH, Hofman A, Jong PT de. Family score as an indicator of genetic risk of primary open-angle glaucoma. Arch Ophthalmol 2002;120:1726-31.

166. Johnston LB, Arends N, Dahlgren J, Leger J, Czernichow P, Albertsson-Wikland K, Duijn CM van, Hokken-Koelega A, Savage MO, Clark AJ. Gene association studies in small for gestational age infants. J Pediatr Endocrinol Metab 2002;15 Suppl 5:1459.

167. Kumar-Singh S, Cras P, Wang R, Kros JM, Swieten J van, Lübke U, Ceuterick C, Serneels, S, Vennekens K, Timmermans JP, Marck E van, Martin JJ, Duijn CM van, Broeckhoven C van. Dense-core senile plaques in the flemish variant of Alzheimer’s disease are vasocentric. Am J Pathol 2002;161:507-20.

168. Maitland-Van Der Zee AH, Stricker BH, Klungel OH, Kastelein JJ, Hofman A, Leufkens HG, Broeckhoven C van, Duijn CM van, Boer A de. The effectiveness of HMG-CoA reductase inhibitors in an elderly population is independent of apolipoprotein E-genotypes. Br J Clin Pharmacol 2002;53:548.

169. Maitland-Van Der Zee AH, Stricker BH, Klungel OH, Kastelein JJ, Hofman A, Witteman JC, Breteler MMB, Leufkens HG, Duijn CM van, Boer A de. The effectiveness of hydroxy-methylglutaryl coenzyme A reductaseinhibitors (statins) in the elderly is not influenced by apolipoprotein E genotype. Pharmacogenetics 2002;12:647-53.

170. Meijers-Heijboer H, Ouweland A van den, Klijn J, Wasielewski M, Snoo A de, Oldenburg R, Hollestelle A, Houben M, Crepin E, Veghel-Plandsoen M van, Elstrodt F, Duijn CM van, Bartels C, Meijers C, Schutte M, McGuffog L, Thompson D, Easton D, Sodha N, Seal S, Barfoot R, Mangion J, Chang-Claude J, Eccles D, Eeles R, Evans DG, Houlston R, Murday V, Narod S, Peretz T, Peto J, Phelan C, Zhang HX, Szabo C, Devilee P, Goldgar D, Futreal PA, Nathanson KL, Weber B, Rahman N, Stratton MR. Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nat Genet 2002;31:55-9.

171. Njajou OT, Hollander M, Koudstaal PJ, Hofman A, Witteman JCM, Breteler MMB, Duijn CM van. Mutations in the hemochromatosis gene (HFE) and stroke. Stroke 2002;10:2363-6.

172. Njajou OT, Jong G de, Berghuis B, Vaessen N, Snijders PJLM, Goossens JP, Wilson JHP, Breuning MH, Oostra BA, Heutink P, Sandkuijl LA, Duijn CM van. Dominant hemochromatosis due to N144H mutations of SLC11A3: Clinical and biological characteristics. Blood Cells Mol Dis 2002;29:439-43.

173. Njajou OT, Vaessen N, Oostra B, Heutink P, Duijn CM van. The hemochromatosisis N144H mutation of SLC11A3 gene in patients with type 2 diabetes. Mol Genet Metab 2002;75:290-1.

174. Njajou OT, Alizadeh BZ, Vaessen N, Vergeer J, Houwing-Duistermaat J, Hofman A, Pols HA, Duijn CM van. The role of hemochromatosis C282Y and H63D gene mutations in type 2diabetes: findings from the Rotterdam Study and meta-analysis. Diabetes Care 2002;25:2112-3

175. Rademakers R, Cruts M, Dermaut B, Sleegers K, Rosso SM, Broeck M van den, Backhovens H, Swieten J van, Duijn CM van, Broeckhoven C van. Tau negative frontal lobe dementia at 17q21: significant finemapping of the candidate region to a 4.8 cM interval. Mol Psychiatry 2002:7;1064-74.

176. Roks G, Cruts M, Houwing-Duistermaat JJ, Dermaut B, Serneels S, Havekes LM, Hofman A, Breteler MMB, Broeckhoven C van, Duijn CM van. Effect of the APOE-491A/T promoter polymorphism on apolipoprotein E levels and risk ofAlzheimer disease: The Rotterdam Study. Am J Med Genet 2002;114:570-3.

177. Rosso SM, Roks G, Broeckhoven C van, Cruts M, Duijn CM van, Swieten JC van. Apolipoprotein E4 in the temporal variant of frontotemporal dementia. J Neurol Neurosurg Psychiatry 2002;72:820.

178. Rossum EF van, Koper JW, Huizenga NA, Uitterlinden AG, Janssen JA, Brinkmann AO, Grobbee DE, Jong FH de, Duijn CM van. A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels. Diabetes 2002;51:3128-34.

179. Ruitenberg A, Swieten JC van, Witteman JCM, Mehta KM, Duijn CM van, Hofman A, Breteler MMB. Alcohol consumption and risk of dementia: the Rotterdam Study. Lancet 2002;359:281-6.

180. Schmidt S, Klaver CCW, Saunders AM, Postel EA, Paz M de la, Agarwal A, Small KW, Udar N, Ong JM, Chalukya MV, Nesburn A, Kenney MC, Domurath RM, Hogan M, Mah TS, Ferrell RE, Weeks DE, Jong PTVM de, Duijn CM van, Haines JL, Pericak-Vance MA, Gorin MA. A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy. Ophthalmic Genet 2002;23:209-23.

181. Slooter AJC, Roks G, Duijn CM van. Genetic association studies. Genes in search of diseases. Neurology 2002;58:1577.

182. Vaessen N, Janssen JA, Heutink P, Hofman A, Lamberts SWJ, Oostra BA, Pols HAP, Duijn CM van. Association between genetic variation in the gene for insulin-like growth factor-I and low birthweight. Lancet 2002;23:1036-7.

183. Vaessen N, Peter Heutink P, Houwing-Duistermaat JJ, Snijders PJLM, Rademaker T, Testers L, Batstra MR, Sandkuijl LA, Duijn CM van, Oostra BA. A genome-wide search for linkage-disequilibrium with type 1 diabetes in a recent genetically isolated population from the Netherlands. Diabetes 2002;51:856-9.

184. Ward HJT, Everington D, Croes EA, Alperovithc A, Delasnerie-Lauprêtre, Zerr I, Poser S, Duijn CM van. The European Union (EU) Collaborative Study Group of Creutzfedt-Jakob Disease (CJD). Sporadic Creutzfeldt-Jakob disease and surgery. A case-control study using community controls. Neurology 2002:59;543-8.

2003

185. Aulchenko YS, Axenovich TI, Mackay I, Duijn CM van. Mild and boold programs for calculation and analysis of corrected linkage disequilibrium. Ann Hum Genet 2003;67:372-5.

186. Aulchenko YS, Vaessen N, Heutink P, Pullen J, Snijders PJLM, Hofman A, Sandkuijl LA, Houwing-Duistermaat JJ, Edwards M, Bennett S, Oostra BA, Duijn CM van. A genome-wide search for genes involved in type 2 diabetes in a recently genetically isolated population from the Netherlands. Diabetes 2003;52:3001-4.

187. Bergink AP, Meurs JB van, Loughlin J, Arp PP, Fang Y, Hofman A, Leeuwen JPTM van, Duijn CM van, Uitterlinden AG, Pols HAP. Estrogen receptor and gene haplotype is associated with radiographic osteoarthritis of the knee in the elderly men and woman. Arthr Rheum 2003;48:1913-22.

188. Bertoli-Avella AM, Giroud-Benitez JL, Bonifati V, Alvarez-Gonzalez E, Heredero-Baute L, Duijn CM van, Heutink P. Suggestive linkage to chromosome 19 in a large Cuban family with late-onset parkinson’s disease. Mov Disord 2003;18:1240-9.

189. Bonifati V, Rizzu P, Baren J van, Schaap O, Breedveld GJ, Krieger E, Dekker MCJ, Squitieri F, Ibanez P, Joosse M, Dongen JW van, Vanacore N, Swieten JC van, Brice A, Meco G, Duijn CM van, Oostra BA, Heutink P. Mutations in the DJ-1 gene associated with autosomal rececessive early-onset parkinsonism. Science 2003;299:256-9.

190. Bonifati V, Rizzu P, Squitieri F, Krieger E, Vanacore N, Swieten JC van, Brice A, Duijn CM van, Oostra B, Meco G, Heutink P. DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism. Neurol Sci 2003;24:159-60.

191. Croes EA, Duijn CM van. Variant Creutzfeldt-Jakob disease. Eur J Epidemiol 2003;18:473-7.

192. Croes EA, Dermaut B, Houwing-Duistermaat JJ, Broeck M van den, Cruts M, Breteler MMB, Hofman A, Broeckhoven C van, Duijn CM van. Early cognitive decline is associated with prion protein codon 129 polymorphism. Ann Neurol 2003;54:275-6.

193. Dekker MCJ, Bonifati V, Swieten J van, Leenders N, Galjaard RJ, Snijders P, Horstink M, Heutink P, Oostra BA, Duijn CM van. Clinical features and neuroimaging of PARK7-linked Parkinsonism. Mov Disord 2003;18:751-7.

194. Dekker MCJ, Bonifati V, Duijn CM van. Parkinson’s disease: piecing together a genetic jigsaw. Brain 2003;126:1722-33.

195. Dekker MCJ, Swieten JC van, Houwing-Duistermaat JJ, Snijders PJLM, Boeren E, Hofman A, Breteler MMB, Heutink P, Oostra BA, Duijn CM van. A clinical-genetic study of Parkinson’s disease in a genetically isolated community. J Neurol 2003;250:1056-62.

196. Dekker MC, Giesbergen PC, Njajou OT, Swieten JC van, Hofman A, Breteler MMB, Duijn CM van. Mutations in the hemochromatosis gene (HFE), Parkinson's disease and parkinsonism. Neurosci Lett 2003;348:117-9.

197. Dekker MCJ, Duijn CM van. Prospects of genetic epidemiology in the 21st century. Eur J Epidemiol 2003;18:607-16.

198. Dermaut B, Croes EA, Rademakers R, Broeck M van den, Cruts M, Hofman A, Duijn CM van, Broeckhoven van C. PRNP Val129 homozygosity increases risk for early-onset Alzheimer’s disease. Ann Neurol 2003;53:409-12.

199. Duijn CM van, Porta M. Good prospects for genetic and molecular epidemiologic studies in the European Journal of Epidemiology. Eur J Epidemiol 2003;18:285-6.

200. Fang Y, Meurs JBJ van, Bergink A, Hofman A, Duijn CM van, Leeuwen JPTM van, Pols, HAP, Uitterlinden A. Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility of fracture in the elderly. J Bone Miner Res 2003;18:1632-41.

201. Houwing-Duistermaat JJ, Bijkerk C, Hsu L, Stijnen T, Slagboom EP, Duijn CM van. A unified approach to modelling linkage to quantitative and qualitative traits. Ann Hum Genet 2003;67:457-63.

202. Maitland-van der Zee AH, Stricker BH, Klungel OH, Mantel-Teeuwisse AK, Kastelein JJ, Hofman A, Leufkens HG, Duijn CM van, Boer A de. Adherence to and dosing of beta-hydroxy-beta-methylglutaryl coenzyme a reductase inhibitors in the general population differs according to apolipoprotein E-genotypes. Pharmacogenetics 2003;13:219-23.

203. Meurs JBJ van, Schuit SCE, Weel AEAM, Klift M van der, Bergink AP, Arp PP, Colin EM, Fang Y, Hofman A, Duijn CM van, Leeuwen JPTM van, Pols HAP, Uitterlinden AG. Association of 5’ estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk. Hum Mol Genet 2003;12:1745-54.

204. Njajou OT, Behrooz ZA, Duijn CM van. Genetic screening for common mutations: Lessons from hereditary hemochromatosis. Eur J Epidemiol 2003;18:3-4.

205. Njajou OT, Houwing-Duistermaat JJ, Osborne RH, Vaessen N, Vergeer J, Heeringa J, Pols HAP, Hofman A, Duijn CM van. A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism. Eur J Hum Genet2003;11:225-31.

206. Rietveld I, Janssen JAMJL, Hofman A, Pols HAP, Duijn CM van, Lamberts SWJ. A polymorphism in the IGF-I gene influences the age-related decline in circulating total IGF-I levels. Eur J Endocrinol 2003;148:171-5.

207. Rietveld I, Janssen JAMJL, Duijn CM van, Lamberts SW. A polymorphic CA repeat in the promoter region of the insulin-like growth factor-I (IGF-I) gene. Eur J Epidemiol 2003;18:191-3.

208. Rivadeneira F, Houwing-Duistermaat JJ, Vaessen N, Vergeer-Drop JM, Hofman A, Pols HA, Duijn CM van, Uitterlinden AG. Association between an insulin-like growth factor I gene promoter polymorphism and bone mineral density in the elderly: the Rotterdam Study. J Clin Endocrinol Metab 2003;88:3878-84.

209. Rosso SM, Kaat LD, Baks T, Joosse M, Koning I de, Pijnenburg Y, Jong D de, Dooijes D, Kamphorst W, Ravid R, Niermeijer, MF, Verheij F, Kremer HP Scheltens P, Duijn CM van, Heutink P, Swieten JC van. Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study. Brain 2003;126:2016-22.

210. Rosso SM, Landweer EJ, Houterman M, Donker Kaat L, Duijn CM van, Swieten JC van.. Medical and environmental risk factors for sporadic frontotemporal dementia: a retrospective case-control study. J Neurol Neurosurg Psychiatry 2003;74:1574-6.

211. Rosso SM, Donker Kaat L, Baks T, Joosse M, Koning I de, Pijnenburg Y, Jong D de, Dooijes D, Kamphorst W, Ravid R, Niermeijer MF, Verheij F, Kremer HP, Scheltens P, Duijn CM van, Heutink P, Swieten JC van. Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study. Brain 2003;126:2016-22.

212. Sayed-Tabatabaei FA, Houwing-Duistermaat JJ, Duijn CM van, Witteman JCM. Angiotensin-converting enzyme gene polymorphism and carotid artery wall thickness a meta-analysis. Stroke 2003;34:1634-9.

213. Schut AFC, Janssen JAMJL, Deinum J, Vergeer JM, Hofman A, Lamberts SWJ, Oostra BA, Pols HAP, Witteman JCM, Duijn CM van. Polymorphism in the promoter region of the insulin-like growth factor I gene is related to carotid intima-media thickness and aortic pulse wave velocity in subjects with hypertension. Stroke 2003;34:1623-7.

2004

214. Alizadeh BZ, Njajou OT, Houwing-Duistermaat JJ, Jong G de, Vergeer JM, Hofman A, Pols AP, Duijn CM van. Does Bilirubin protect against hemochromatosis gene (HFE) related mortality? Am J Med Genet 2004;129:39-43.

215. Arias Vásquez A, Sleegers K, Dekker MCJ, Gool WA van, Swieten JC van, Aulchenko YS, Oostra BA, Duijn CM van. A deletion in DJ-1 and the risk of dementia – a population-based survey. Neurosci Lett 2004;372:196–9.

216. Aulchenko YS, Heutink P, Mackay I, Bertoli-Avella AM, Pullen J, Vaessen N, Rademaker TA, Sandkuijl LA, Cardon L, Oostra B, Duijn CM van. Linkage disequilibrium in young genetically isolated Dutch population. Eur J Hum Genet 2004;12:527-34.

217. Bleumink GS, Duijn CM van, Kingma JH, Witteman JC, Hofman A, Stricker BH. Apolipoprotein E epsilon4 allele is associated with left ventricular systolic dysfunction. Am Hear J 2004;147:685-9.

218. Bleumink GS, Rietveld I, Janssen JAMJL, Rossum EFC van, Deckers JW, Hofman A, Witteman JCM, Duijn CM van, Stricker BHCh. Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study). Am J Cardiol 2004;94:384-6.

219. Bleumink GS, Schut AF, Sturkenboom MC, Deckers JW, Duijn CM van, Stricker BH. Genetic polymorphisms and heart failure. Genet Med 2004;6:465-74.

220. Cammen TJ van der, Croes EA, Dermaut B, Jager MC de, Cruts M, Broeckhoven C van, Duijn CM van. Genetic testing has no place as a routine diagnotic test in sporadic and familial cases of Alzheimer’s disease. J Am Geriatr Soc 2004;52:2110-3.

221. Croes EA, Theuns J, Houwing-Duistermaat JJ, Dermaut B, Sleegers K, Roks G, Broeck M van den, Harten B van, Swieten JC van, Cruts M, Broeckhoven C van, Duijn CM van. Octapeptide repeat insertions in the prion protein gene and early onset dementia. J Neurol Neurosurg Psychiatry 2004;75:1166-70.

222. Croes EA, Alizadeh BZ, Bertoli-Avella AM, Rademaker T, Vergeer-Drop J, Dermaut B, Houwing-Duistermaat JJ, Wientjens DP, Hofman A, Broeckhoven C van, Duijn CM van. Polymorphisms in the prion protein gene and in the doppel gene increase susceptibility for Creutzfeldt-Jakob disease. Eur J Hum Genet 2004;12:389-94.

223. Dekker MC, Galjaard RJ, Snijders PJ, Heutink P, Oostra BA, Duijn CM van. Brachydactyly and short stature in a kindred with early-onset parkinsonism. Am J Med Genet 2004;130A:102-4.

224. Dekker MC, Eshuis SA, Maguire RP, Veenma-van der Duijn L, Pruim J, Snijders PJ, Oostra BA, Duijn CM van, Leenders KL. PET neuroimaging and mutations in the DJ-1 gene. J Neural Transm 2004;111:1575-81.

225. Dekker MCJ, Nelson LM, Duijn CM van. Genetic Epidemiology of Neurologic Disease. Book Neuroepidemiology From Principles to Practice (Nelson LM, Tanner CM, Eeden SK van den McGuire VM);2004:85-101.

226. Dijk EJ van, Prins ND, Vermeer SE, Hofman A, Duijn CM van, Koudstaal PJ, Breteler MMB. Plasma amyloid beta, apolipoprotein E, lacunar infarcts and white matter lesions Ann Neurol 2004;55:570-5.

227. Duijn CM van. Prospects of genetic research of mild cognitive impairment. J Intern Med 2004;256:235-9.

228. Geleijnse K, Brouwer BA, Jacobs BC, Houwing-Duistermaat JJ, Duijn CM van, Doorn PA van. The occurrence of Guillain-Barre syndrome within families. Neurology 2004;63:1747-50.

229. ‘t Hart LM, Fritsche A, Rietveld I, Dekker JM, Nijpels G, Machicao F, Stumvoll M, Duijn CM van, Haring HU, Heine RJ, Maassen JA, Haeften TW van. Genetic factors and insulin secretion: gene variants in the IGF genes. Diabetes 2004;53:26-30.

230. Heijer T den, Schuit SCE, Pols HAP, Meurs JBJ van, Hofman A, Koudstaal PJ, Duijn CM van, Uitterlinden AG, Breteler MMB. Variations in estrogen receptor gene and risk of dementia, and brain volumes on MRI. Mol Psychiatry 2004;1129-35.

231. Heijer T den, Vermeer SE, Dijk EJ van, Prins ND, Koudstaal PJ, Duijn CM van, Hofman A, Breteler MMB. Alcohol intake in relation to brain magnetic resonance imaging findings in older persons whithout dementia. Am J Clin Nutr 2004;80:992-7.

232. Houben MPWA, Louwman WJ, Tijssen CC, Teepen JLJM, Duijn CM van, Coebergh JWW. Hypertension as a risk factor for glioma? Evidence from a population-based study of comorbidity in glioma patients. Ann Oncol 2004;15:1256-60.

233. Isaacs A, Sayed-Tabatabaei FA, Njajou OT, Witteman JC, Duijn CM van. The –514C->T hepatic lipase prmotor region polymorphosm and plasma lipids: a meta-analysis. J Clin Endocrinol Metab 2004;89:3858-63.

234. Janssens AC, Pardo MC, Steyerberg EW, Duijn CM van. Revisiting the clinical validity of multiplex genetic testing in complex diseases. Am J Hum Genet 2004;74:585-8.

235. Leeuw FE de, Richard F, Groot JC de, Duijn CM van, Hofman A, Gijn J van, Breteler MMB. Interaction between hypertension, apoE and cerebral white matter lesions. Stroke, 2004;35:1057-60.

236. Leeuwen R van, Klaver CC, Vingerling JR, Hofman A, Duijn CM van, Stricker BH, Jong PT de. Cholesterol and age-related macular degeneration: is there a link? Am J Ophthalmol 2004;137:750-2.

237. Maitland-van der Zee AH, Klunger OH, Stricker BH, Veenstra DL, Kastelein JJ, Hofman A, Witteman JC, Leufkens HG, Duijn CM van, Boer A de. Pharmacoeconomic evaluation of testing for angiotensin-converting enzyme genotype before starting beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitor therapy in men. Pharmacogenetics 2004;14:53-60.

238. Maitland-van der Zee AH, Stricker BH, Klungel OH, Kastelein JJ, Hofman A, Witteman JC, Leufkens HG, Duijn CM van, Boer AA. Effectiveness of HMG-CoA reductase inhibitors is modified by the ACE insertion deletion polymorphism. Atherosclerosis 2004;175:377-9.

239. Mattace-Raso FU, Cammen TJ van der, Sayed-Tabatabaei FA, Popele NM van, Asmar R, Schalekamp MA, Hofman A, Duijn CM van, Witteman JC. Antiotensin-converting enzyme gene polymorphism and common carotid stiffness. The Rotterdam Study. Atheroclerosis 2004;174:121-6.

240. Meulenbelt I, Seymour AB, Nieuwland M, Huizinga TW, Duijn CM van, Slagboom PE. Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip. Arthritis Rheum 2004;50:1179-86.

241. Nijs PF de, Ferdinand RF, Bruin EI de, Dekker MC, Duijn CM van, Verhulst DC. Attention-deficit/hyperactivity disorder (ADHD): parents’ judgment about school, teacher’s judgement about home. Eur Child Adolesc Psychiatry 2004;13:315-20.

242. Njajou OT, Alizadeh BZ, Duijn CM van. Is genetic screening for hemochromatosis worthwhile? Eur J Epidemiol 2004;19:101-8.

243. Pocchiari M, Puopolo M, Croes EA, Budka H. Gelpi E, Collins S, Lewis V, Sutcliffe T, Guilivi A, Delasnerie-Laupretre N, Brandel JP, Alperovitch A, Zerr I, Poser S, Kretzschmar HA, Ladogana A, Rietvald I, Mitrova E, Martinez-Martin P, Pedro-Cuesta J de, Glatzel M, Aguzzi A, Cooper S, Mackenzie J, Duijn CM van, Will RG. Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies. Brain 2004:127;2348-59.

244. Rademakers R, Broeck M van den, Sleegers K, Duijn CM van, Broeckhoven C van, Cruts M. Absence of pathogenic mutations in presenilin homologue 2 in a conclusively 17-linked tau-negative dementia family. Neurogenetics 2004;5:79-80.

245. Rietveld I, Janssen JAMJL, Rossum EFC van, Houwing-Duistermaat JJ, Rivadeneira F, Hofman A, Pols HAP, Duijn CM van, Lamberts SWJ. A polymorphic CA repeat in the IGF-I gene is associated with gender-specific differences in body height, but has no effect on the secular trend in body height. Clin Endocrinol 2004;61:195-203.

246. Rivadeneira F, Houwing-Duistermaat JJ, Beck TJ, Janssen JA, Hofman A, Pols HA, Duijn CM van, Uitterlinden AG. The influence of an insulin-like growth factor I gene promotor polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study. J Bone Miner Res 2004;19:1280-90.

247. Sayed-Tabatabaei FA, Schut AF, Hofman A, Bertoli-Avella AM, Vergeer J, Witteman JC, Duijn CM van. A study of gene-environment interaction on the gene for angiotensin converting enzyme: a combined functional and population based approach. J Med Genet 2004;41:99-103.

248. Schelleman H, Stricker BH, Boer A de, Kroon AA, Verschuren MW, Duijn CM van, Psaty BM, Klungel OH. Drug-gene interactions between generic polymorphisms and antihypertensive therapy. Drugs 2004;64:1801-16.

249. Schmidt H, Aulchenko YS, Schweighofer N, Schmidt R, Frank S, Kostner GM Ott E, Duijn CM van. Angiotensinogen promoter B-haplotype associated with cerebral small vessel disease enhances basal transcriptional activity. Stroke 2004;35:2592-7.

250. Schoofs MW, Klift M van der, Hofman A, Duijn CM van, Stricker BH, Pols HA, Uitterlinden AG. ApoE gene polymorphisms, BMD, and fracture risk in elderly men and women: the Rotterdam Study. J Bone Miner Res 2004;19:1490-6.

251. Schut AF, Sayed-Tabatabaei FA, Witteman JC, Avella AM, Vergeer JM, Pols HA, Hofman A, Deinum J, Duijn CM van. Smoking-dependent effects of the antiotensin-converting enzyme gene insertion/deletion polymorphism on blood pressure. J Hypertens 2004;22:313-9.

252. Schut AF, Bleumink GS, Stricker BH, Hofman A, Witteman JC, Pols HA, Deckers JW, Deinum J. Duijn CM van. Angiotensin converting enzyme insertion/deletion polymorphism and the risk of heart failure in hypertensive subjects. Eur Heart J 2004;2143-8.

253. Sleegers K, Roks G, Theuns J. Aulchenko YS, Rademakers R, Cruts M. Gool WA van, Broeckhoven C van, Heutink P, Oostra BA, Swieten JC van, Duijn CM van. Familial clustering and genetic risk for dementia in a genetically isolated Dutch population. Brain 2004;127:1641-9.

254. Sleegers K, Weber WEJ, Duijn CM van. Neuro-epidemiologie. Book Praktische Huisartsgeneeskunde Neurologie (Ree van JW, Martin JJ) 2004;25-37.

255. Slooter AJ, Cruts M, Hofman A, Koudstaal PJ, Kuip D van der, Ridder MA de, Witteman JC, Breteler MMB, Broeckhoven C van, Duijn CM van. The impact of APOE on myocardial infarction, stroke and dementia: the Rotterdam Study. Neurology 2004;62:1196-8.

256. Winblad B, Palmer K, Kivipelto M, Jelic V, Fratiglioni L, Wahlund LO, Nordberg A, Backman L, Albert M, Almkvist O, Arai H, Basun H, Blennow K, Leon M de, DeCarli C, Erkinjuntti T, Giacobini E, Graff C, Hardy J, Jack C, Jorm A, Ritchie K, Duijn CM van, Visser P, Petersen RC. Mild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment. J Intern Med 2004;256:240-6.

257. West D van, Del-Favero J, Aulchenko Y, Oswald P, Souery D, Forsgren T, Sluijs S, Bel-Kacem S, Adolfsson R, Mendlewicz J. Duijn CM van, Deboutte D, Broeckhoven C van. A

major SNP haplotype of the arginine vasopressin 1B receptor protects against recurrent major depression. Mol Psychiatry 2004;9:287-92.

258. Visser LE, Vliet M van, Schaik RHN van, Kasbergen AAH, Smet PAGM de, Vulto AG, Homan A, Duijn CM van, Stricker BHCh. The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon. Pharmacogenetics 2004;14:27-33.

259. Visser LE, Schaik RHN van, Vliet M van, Trienekens PH, Smet PAGM de, Vulto AG, Hofman A, Duijn CM van. The risk of bleeding complications in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol of phenprocoumon. Thromb Haemost 2004;92:61-6.

260. Zhai G, Rivadeneira F, Houwing-Duistermaat JJ, Meulenbelt I, Bijkerk C, Hofman A, Meurs JBJ van, Uitterlinden AG, Pols HAP, Slagboom PE, Duijn CM van. Insulin-like growth factor I gene promoter polymorphism, collagen type II α1 (COL2A1) gene, and the prevalence of radiographic osteoarthritis: the Rotterdam Study. Ann Rheum Dis 2004;63:544-8.

2005

261. Alizadeh BZ, Njajou OT, Bijkerk C, Meulenbelt I, Wildt SC, Hofman A, Pols HA, Slagboom PE, Duijn CM van. Evidence for a role of the genomic region of the gene encoding for the alphal chain of type IX collagen (COL9A1) in hip osteoarthritis: A population-based study. Arthritis Rheum 2005;52:1437-42.

262. Arias-Vasquez A, Sayed-Tabatabaei FA, Schut AF, Hofman A, Bertoli-Avella AM, Vergeer JM, Aulchenko YS, Witteman JC, Duijn CM van. Angiotensin converting enzyme gene, smoking and mortality in a population-based study. Eur J Clin Invest 2005;35:444-9.

263. Assink JJ, Klaver CC, Houwing-Duistermaat JJ, Wolfs RC, Duijn CM van, Hofman A, Jong PT de. Heterogeneity of the genetic risk in age-related macular disease: a population-based familial risk study. Ophthalmology 2005;112:482-7.

264. Aulchenko YS, Bertoli-Avella AM, Duijn CM van. A method for pooling alleles from different genotyping experiments. Ann Hum Genet 2005;69:233-8.

265. Bertoli-Avella AM, Giroud-Benitez JL, Akyol A, Barbosa E, Schaap O, Linde HC van der, Martignoni E, Lopiano L, Lamberti P, Fincati E, Antonini A, Stocchi F, Montagna P, Squitieri F, Marini P, Abbruzzese G, Fabbrini G, Marconi R, Dalla Libera A, Trianni G, Guidi M, Gaetano A de, Boff Maegawa G, Leo A de, Gallai V, Rosa G de, Vanacore N, Meco G, Duijn CM van, Oostra BA, Heutink P, Bonifati V. Novel parkin mutations detected in patients with early-onset Parkinson’s disease. Mov Disord 2005;20:424-31.

266. Bertoli-Avella A, Dekker MCJ, Aulchenko YS, Houwing-Duistermaat JJ, Simons E, Testers L, Pardo LM, Rademaker TAM, Snijders PJLM, Swieten JC van, Bonifati V, Heutink P, Duijn CM van, Oostra BA. Evidence for novel loci for late-onset Parkinson’s disease in a genetic isolate from the Netherlands. Hum Genet 2005;14:1-10.

267. Bleumink GS, Schut AF, Sturkenboom MC, Duijn CM van, Deckers JW, Hofman A, Kingma JH, Witteman JC, Stricker BH. Mortality in patients with hypertension on angiotensin-I

converting enzyme (ACE)-inhibitor treatment is influenced by the ACE insertion/deletion polymorphism. Pharmacogenet Genomics 2005;15:75-81.

268. Bleumink GS, Schut AF, Sturkenboom MC, Janssen JA, Witteman JC, Duijn CM van, Hofman A, Stricker BH. A promoter polymorphism of the insulin-like growth factor-I gene is associated with left ventricular hypertrophy. Heart 2005;91:239-40.

269. Bunce C, Hitchings RA, Duijn CM van, Jong PT de, Vingerling JF. Associations between the deletion polymorphism of the angiotensin 1-converting enzyme gene and ocular signs of primary open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol 2005;243:294-9.

270. Croes EA, El Galta R, Houwing-Duistermaat JJ, Ferdinand RF, Lopez Leon S, Rademaker TA, Dekker MC, Oostra BA, Verhulst F, Duijn CM van. Phenotypic subtypes in attention deficit hyperactivity disorder in an isolated population. Eur J Epidemiol 2005;20:789-94.

271. El Galta R, Duijn CM van, Houwelingen C van, Houwing-Duistermaat JJ. Score statistic to test for genetic correlation for proband-family design. Ann Hum Genet 2005;69:373-381.

272. González-Zuloeta Ladd AM, Arias Vásquez A, Sayed-Tabatabaei FA, Coebergh JW, Hofman A, Njajou O, Stricker B, Duijn CM van. Angiotensin-converting enzyme gene insertion/deletion polymorphism and breast cancer risk. Cancer Epidemiol Biomarkers Prev 2005;14:2143-6.

273. 't Hart LM, Hansen T, Rietveld I, Dekker JM, Nijpels G, Janssen GM, Arp PA, Uitterlinden AG, Jorgensen T, Borch-Johnsen K, Pols HA, Pedersen O, Duijn CM van, Heine RJ, Maassen JA. Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene. Diabetes 2005;54:1892-5.

274. Houben MPWA, Coebergh JWW, Birch JM, Tijssen CC, Duijn CM van, McNally RJQ. Space-time clustering patterns of gliomas in the Netherlands suggest an infectious aetiology. Eur J Cancer 2005;41:2917-23.

275. Houben MPWA, Duijn CM van, Coebergh JW, Tijssen CC. Gliomas: the role of environmental risk factors and genetic predisposition. Ned Tijdschr Geneeskd 2005;149:2268-72.

276. Jansen C, Houben MPWA, Hoff JI, Sanchez-Juan P, Rozemuller AJ, Duijn CM van. The first patient with the new variant of Creutzfeldt-Jakob’s disease in The Netherlands. Ned Tijdschr Geneeskd 2005;149:2949-54.

277. Kovács GG, Puopolo M, Ladogana A, Pocchiari M, Budka H, Duijn CM van, Collins SJ, Boyd A, Giulivi A, Coulthart M, Delasnerie-Laupretre N, Brandel JP, Zerr I, Kretzschmar HA, Pedro-Cuesta J de, Calero-Lara M, Glatzel M, Aguzzi A, Bishop M, Knight R, Belay G, Will R, Mitrova E; EUROCJD. Genetic prion disease: the EUROCJD experience. Hum Genet 2005;118:166-74.

278. Ladogana A, Puopolo M, Croes EA, Budka H, Jarius C, Collins S, Klug GM, Sutcliffe T, Giulivi A, Alperovitch A, Delasnerie-Laupretre N, Brandel JP, Poser S, Kretzschmar H, Rietveld I, Mitrova E, Cuesta JP de, Martinez-Martin P, Glatzel M, Aguzzi A, Knight R, Ward H, Pocchiari M. Duijn CM van, Will RG, Zerr I. Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada. Neurology 2005:64;1586-91.

279. Lehmann DJ, Cortina-Borja M, Warden DR, Smith AD, Sleegers K, Prince JA, Duijn CM van, Kehoe PG. Large Meta-Analysis Establishes the ACE Insertion-Deletion Polymorphism as a Marker of Alzheimer’s Disease. Am J Epidemiol 2005;162:305-317.

280. Lopez Leon S, Croes EA, Sayed-Tabatabaei FA, Claes S, Broeckhoven C van, Duijn CM van. The dopamine D4 receptor gene 48-base-pair-repeat polymorphism and mood disorders: a meta-analysis. Biol Psychiatry 2005;57:999-1003.

281. Min JL, Meulenbelt I, Riyazi N, Kloppenburg M, Houwing-Duistermaat JJ, Seymour AB, Pols HA, Duijn CM van, Slagboom PE. Association of the Frizzled-related protein gene with symptomatic osteoarthritis at multiple sites. Arthritis Rheum 2005;52:1077-80.

282. Oei HH, Sayed-Tabatabaei FA, Hofman A, Oudkerk M, Duijn CM van, Witteman JC. The association between angiotensin-converting enzyme gene polymorphism and coronary calcification. The Rotterdam Coronary Calcification Study. Atherosclerosis 2005;182:169-73.

283. Pardo LM, Duijn CM van. In search of genes involved in neurodegenerative disorders. Mutat Res 2005;592:89-101.

284. Pardo LM, MacKay I, Oostra B, Duijn CM van, Aulchenko YS. The effect of genetic drift in a young genetically isolated population. Ann Hum Genet 2005;69:288-95.

285. Rademakers R, Cruts M, Sleegers K, Dermaut B, Theuns J, Aulchenko Y, Weckx S, DePooter T, Broeck M van den, Corsmit E, Rijk P de, Del-Favero J, Swieten J van, Duijn CM van, Broeckhoven C van. Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample. Am J Hum Genet 2005;77:643-52.

286. Rademakers R, Sleegers K, Theuns J, Broeck M van den, Bel Kacem S, Nilsson LG, Adolfsson R, Duijn CM van, Broeckhoven C van, Cruts M. Association of cyclin-dependent kinase 5 and neuronal activators p35 and p39 complex in early-onset Alzheimer’s disease Neurobiol Aging 2005;26:1145-51.

287. Rijn MJE van, Slooter AJ, Schut AF, Isaacs A, Aulchenko YS, Snijders PJ, Kappelle LJ, Swieten JC van, Oostra BA, Duijn CM van. Familial aggregation, the PDE4D gene, and ischemic stroke in a genetically isolated population. Neurology 2005;65:1203-9.

288. Rijn MJE van, Duijn CM van, Slooter AJC. The impact of genetic testing on complex diseases. Eur J Epidemiol 2005;20:383-8.

289. Sayed-Tabatabaei FA, Rijn MJ van, Schut AF, Aulchenko YS, Croes EA, Zillikens MC, Pols HA, Witteman JC, Oostra BA, Duijn CM van. Heritability of the function and structure of the arterial wall: findings of the Erasmus Rucphen Family (ERF) study. Stroke 2005;36:2351-6.

290. Sayed-Tabatabaei FA, Schut AF, Vasquez AA, Bertoli-Avella AM, Hofman A, Witteman JC, Duijn CM van. Angiotensin converting enzyme gene polymorphism and cardiovascular morbidity and mortality: the Rotterdam Study. J Med Genet 2005;42:26-30.

291. Schelleman H, Klungel OH, Duijn CM van, Witteman JC, Hofman A, Boer A de, Stricker BH. Insertion/deletion polymorphism of the ACE gene and adherence to ACE inhibitors. Br J Clin Pharmacol 2005;59:483-5.

292. Sleegers K, Heijer T den, Dijk EJ van, Hofman A, Bertoli-Avella AM, Koudstaal PJ, Breteler MMB, Duijn CM van. ACE gene is associated with Alzheimer’s disease and atrophy of hippocampus and amygdala. Neurobiol Aging 2005;26:1153-9.

293. Venken T, Claes S, Sluijs S, Paterson AD, Duijn CM van, Adolfsson R, Del-Favero J, Broeckhoven C van. Genomewide scan for affective disorder susceptibility loci in families of a northern Swedish isolated population. Am J Hum Genet 2005;76:237-48.

294. Visser LE, Trienekens PH, Smet PA de, Vulto AG, Hofman A, Duijn CM van, Stricker BH. Patients with an ApoE epsilon4 allele require lower doses of coumarin anticoagulants. Pharmacogenet Genomics 2005;15:69-74.

295. Visser LE, Schaik RHN van, Vliet M van, Trienekens PH,Smet PAGM de, Vulto AG, Hofman A, Duijn CM van, Stricker BHCh. Allelic variants of cytochrome P450 2C9 modify the interaction between nonsteroidal anti-inflammatory drugs and coumarin anticoagulants. Clin Pharmacol Ther 2005;77:479-85.

2006

296. Bertoli-Avella AM, Dekker MC, Aulchenko YS, Houwing-Duistermaat JJ, Simons E, Testers L, Pardo LM, Rademaker TA, Snijders PJ, Swieten JC van, Bonifati V, Heutink P, Duijn CM van. Evidence for novel loci for late-onset Parkinson’s disease in a genetic isolate from the Netherlands. Hum Genet 2006;119:51-60.

297. Brouwers N, Sleegers K, Engelborghs S, Bogaerts V, Duijn CM van, Deyn PP de, Broeckhoven C van, Dermaut B. The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer’s disease with onset before 70 years. Neurosci Lett 2006;392:72-4.

298. Collins SJ, Sanchez-Juan P, Masters CL, Klug GM, Duijn CM van, Poleggi A, Pocchiari M, Almonti S, Cuadrado-Corrales N, Pedro-Cuesta J de, Budka H, Gelpi E, Glatzel M, Tolnay M, Hewer E, Zerr I, Heinemann U, Kretszchmar HA, Jansen GH, Olsen E, Mitrova E, Alpérovitch A, Brandel JP, Mackenzie J, Murray K, Will RG. Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease. Brain. 2006;129:2278-87.

299. Coppus AMW, Evenhuis H, Verberne GJ, Visser F, Gool P van, Eikelenboom P, Duijn CM van. Dementia and mortality in persons with Down’s syndrome. J Intellect Disabil Res 2006;50:768-77.

300. Cruts M, Gijselinck I, Zee J van der, Engelborghs S, Wils H, Pirici D, Rademakers R, Vandenberghe R, Dermaut B, Martin JJ, Duijn CM van, Peeters K, Sciot R, Santens P, Pooter T de, Mattheijssens M, Broeck M van den, Cuijt I, Vennekens K, Deyn PP de, Kumar-Singh S, Broeckhoven C van. Null Mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21. Nature 2006;442:920-4.

301. Despriet DD, Klaver CC, Witteman JC, Bergen AA, Kardys I, Maat MP de, Boekhoorn SS, Vingerling JR, Hofman A, Oostra BA, Uitterlinden AG, Stijnen T, Duijn CM van, Jong PT

de. Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration. JAMA 2006;296:301-9.

302. Duijn CM van, Ruijs H, Timen A. Second probable case of vCJD in the Netherlands. Euro Surveill 2006;11:E060629.4.

303. Gonzalez-Zuloeta Ladd AM, Arias Vasquez AA, Witteman J, Uitterlinden AG, Coebergh CW, Hofman A, Stricker BH, Duijn CM van. Interleukin 6 G-174 C polymorphism and breast cancer risk. Eur J Epidemiol 2006;21:373-6.

304. Hofman A, Jong PTVM de, Duijn CM van, Breteler MMB. Epidemiology of neurological diseases in elderly people: what did we learn from the Rotterdam Study? Lancet Neurol 2006;5:545-50.

305. Houben MPWA, Coebergh JWW, Birch JM, Tijssen CC, Duijn CM van, McNally RJQ. Space-time clustering of glioma cannot be attributed to specific histological subgroups. Eur J Epidemiol 2006;21:197-201.

306. Houben MPWA, Aben KK, Teepen JL, Schouten-Van Meeteren AY, Tijssen CC, Duijn CM van, Coebergh JW. Stable incidence of childhood and adult glioma in The Netherlands, 1989-2003. Acta Oncol 2006;45:272-9.

307. Houben MPWA, Coebergh JW, Herings RM, Casparie MK, Tijssen CC, Duijn CM van, Stricker BH. The association between antihypertensive drugs and glioma. Br J Cancer 2006;94:752-6.

308. Ikram MK, Janssen JA, Roos AM, Rietveld I, Witteman JC, Breteler MMB, Hofman A, Duijn CM van, Jong PT van. Retinal vessel diameters and risk of impaired fasting glucose or diabetes: the Rotterdam Study. Diabetes 2006;55:506-10.

309. Janssens ACJW, Aulchenko YS, Elefante S, Borsboom GJJM, Steyerberg EW, Duijn CM van. Predictive testing for complex diseases using multiple genes: Fact or fiction. Genet Med 2006;8:395-400.

310. Janssens ACJW, Duijn CM van. Towards predictive genetic testing of complex diseases (Editorial). Eur J Epidemiol 2006;21:869-870.

311. Janssens ACJW, Steyerberg EW, Jiang Y, Habbema JD, Duijn CM van, Criswell LA. Value of the HLA-DRB1 shared epitope for predicting radiographic damage in rheumatoid arthritis depends on the individual patient risk profile. J Rheumatol 2006;33:2383-9.

312. Kardys I, Klaver CC, Despriet DD, Bergen AA, Uitterlinden AG, Hofman A, Oostra BA, Duijn CM van, Jong PTVM de, Witteman JC. A common polymorphism in the complement factor H gene is associated with increased risk of myocardial infarction: the Rotterdam Study. J Am Coll Cardiol 2006;47:1568-75.

313. Liu F, Elefante S, Duijn CM van, Aulchenko YS. Ignoring distant genealogic loops leads to false-positives in homozygosity mapping. Ann Hum Genet 2006;70:965-70.

314. Lopez-Leon S, Janssens ACJW, Hofman A, Claes S, Breteler MMB, Tiemeier H, Duijn CM van. No association between the angiotensin-converting enzyme gene and major depression: a case-control study and meta-analysis. Psychiatr Genet 2006;16:225-6.

315. Meulenbelt I. Min JL, Duijn CM van, Kloppenburg M, Breeveld FC, Slagboom PE. Strong linkage on 2q33.3 to familial early-onset generalized osteoarthritis and a consideration of two positional candidate genes. Eur J Hum Genet 2006;14:1280-7.

316. Min JL, Meulenbelt I, Riyazi N, Kloppenburg M, Houwing-Duistermaat JJ, Seymour AB, Duijn CM van, Slagboom PE. Association of matrilin-3 polymorphisms with spinal disc degeneration and osteoarthritis of the first carpometacarpal joint of the hand. Ann Rheum Dis 2006;65:1060-6.

317. Njajou OT, Alizadeh BZ, Aulchenko Y, Zillikens MC, Pols HA, Oostra BA, Swinkels DW, Duijn CM van. Heritability of serum iron, ferritin and transferrin saturation in a genetically isolated population, the Erasmus Rucphen Family (ERF) Study. Hum Hered 2006;61:222-8.

318. Pedro-Cuesta J de, Glatzel M, Almazán J, Stoeck Katharina, Mellina V, Puopolo M, Pocchiari M, Zerr I, Kretszchmar HA, Brandel JP, Delasnerie-Lauprêtre N, Alpérovitch A, Duijn CM van, Sanchez-Juan P, Collins S, Lewis V, Jansen GH, Coulthart MB, Gelphi E, Budka H, Mitrova E. Human transmissible spongiform encephalopahties in eleven countries: diagnostic pattern across time, 1993-2002. BMC Public Health 2006;6:278.

319. Rietveld I, Hofman A, Pols HA, Duijn CM van, Lamberts SW, Janssen JA. An insulin-like growth factor-I gene polymorphism modifies the risk of microalbuminuria in subjects with an abnormal glucose tolerance. Eur J Endocrinol 2006;154:715-21.

320. Rietveld I, Ikram MK, Vingerling JR, Hofman A, Pols HA, Lamberts SW, Jong PT de, Duijn CM van, Janssen JA. An ifg-I gene polymorphism modifies the risk of diabetic retinopathy. Diabetes 2006;55:2387-91.

321. Rijn MJ van, Slooter AJ, Bos MJ, Catarino CF, Koudstaal PJ, Hofman A, Breteler MMB, Duijn CM van. Insulin-like growth factor I promoter polymorphism, risk of stroke, and survival after stroke: the Rotterdam Study. J Neurol Neurosurg Psychiatry 2006;77:24-7.

322. Rijn MJ, Bos MJ, Yazdanpanah M, Isaacs A, Arias-Vasquez A, Koudstaal PJ, Hofman A, Witteman JC, Duijn CM van, Breteler MMB. Alpha-adducin polymorphism, atherosclerosis, and cardiovascular and cerebrovascular risk. Stroke 2006;37:2930-4.

323. Rivadeneira F, Meurs JB van, Kant J, Zillikens MC, Stolk L, Beck TJ, Arp P, Schuit SC, Hofman A, Houwing-Duistermaat JJ, Duijn CM van, Leeuwen JP, Pols HA, Uitterlinden AG. Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women. J Bone Miner Res 2006;21:1443-56.

324. Sanchez-Juan P, Green A, Ladogana A, Cuadrado-Corrales N, Saanchez-Valle R, Mitrovaa E, Stoeck K, Sklaviadis T, Kulczycki J, Hess K, Bodemer M, Slivarichova D, Saiz A, Calero M, Ingrosso L, Knight R, Janssens ACJW, Duijn CM van, Zerr I. CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease. Neurology 2006;67:637-43.

325. Santos RLP, Zillikens MC, Rivadeneira FR, Pols HAP, Oostra BA, Duijn CM van, Aulchenko YS. Heritability of fasting glucose levels in a young genetically isolated population. Diabetologia 2006;49:667-72.

326. Sayed-Tabatabaei FA, Oostra BA, Isaacs A, Duijn CM van, Witteman JCM. ACE Polymorphisms. Circ Res 2006;98:1123-33.

327. Schelleman H, Klungel OH, Duijn CM van, Witteman JC, Hofman A, Boer A de, Stricker BH. Drug-Gene interaction between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and antihypertensive therapy. Ann Pharmacother 2006;40:212-8.

328. Schelleman H, Klungel OH, Witteman JC, Hofman A, Duijn CM van, Boer A de, Stricker BH. The influence of the alpha-adducin G460W polymorphism and angiotensinogen M235T polymorphism on antihypertensive medication and blood pressure. Eur J Hum Genet 2006;14:860-6.

329. Service S, DeYoung J, Karayiorgou M, Roos JL, Pretorious H, Bedoya G, Ospina J, Ruiz-Linares A, Macedo A, Palha JA, Heutink P, Aulchenko Y, Oostra B, Duijn CM van, Jarvelin MR, Varilo T, Peddle L, Rahman P, Piras G, Monne M, Murray S, Galver L, Peltonen L, Sabatti C, Collins A, Freimer N. Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. Nat Genet 2006:556-60.

330. Sie MP, Uitterlinden AG, Bos MJ, Arp PP, Breteler MM, Koudstaal PJ, Pols HA, Hofman A, Duijn CM van, Witteman JC. TGF-beta 1 polymorphisms and risk of myocardial infarction and stroke: the Rotterdam Study. Stroke 2006;37:2667-71

331. Sie MP, Sayed-Tabatabaei FA, Oei HH. Uitterlinden AG, Pols HA, Hofman A, Duijn CM van, Witteman JC. Interleukin 6-174 g/c promoter polymorphism and risk of coronary heart disease: result from the rotterdam study and a meta-analysis. Arterioscler Thromb Vasc Biol 2006;26:212-7.

332. Sleegers K, Brouwers N, Gijselinck I, Theuns J, Goossens D, Wauters J, Del-Favero J, Cruts M, Duijn CM van, Broeckhoven C van. APP duplication is sufficient to cause early onset Alzheimer’s dementia with cerebral amyloid angiopathy. Brain 2006;129:2977-83.

333. Theuns J, Brouwers N, Engelborghs S, Sleegers K, Bogaerts V, Corsmit E, Poorter T de, Duijn CM van, Deyn PP de, Broeckhoven C van. Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease. Am J Hum Genet 2006;78:936-46.

334. West D van, Eede F van den, Del-Favero J, Souery D, Norrback KF, Duijn CM van, Sluijs S, Adolfsson R, Mendlewicz J, Deboutte D, Broeckhoven C van, Claes S. Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression. Neuropsychopharmacology 2006;31:620-7.

335. Yazdanpanah M, Rietveld I, Janssen JA, Njajou OT, Hofman A, Stijnen T, Pols HA, Lamberts SW, Witteman JC, Duijn CM van. An insulin-like growth factor-I promoter polymorphism is associated with increased mortality in subjects with myocardial infarction in an elderly Caucasian population. Am J Cardiol 2006;97:1274-6.

336. Yazdanpanah M, Sayed-Tabatabaei FA, Janssen JAMJL, Rietveld I, Hofman A, Stijnen Th, Pols HAP, Lamberts SWJ, Witteman JCM, Duijn CM van. IGF-I gene promoter polymorphism is a predictor of survival after myocardial infarction in patients with type 2 diabetes. Eur J Endocrinol 2006;155:1-7.

337. Yazdanpanah M, Sayed-Tabatabaei FA, Hofman A, Aulchenko YS, Oostra BA, Stricker BH, Pols HA, Lamberts SW, Witteman JC, Janssen JA, Duijn CM van. The{alpha}–adducin gene is associated with macrovascular complications and mortality in patients with type 2 diabetes. Diabetes 2006;55:2922-7.

2007

338. Alizadeh BZ, Njajou OT, Hazes JM, Hofman A, Slagboom PE, Pols HAP, Duijn CM van. The H63D mutation in the HFE gene predisposes to arthralgia, chondrocalcinosis, and osteoarthritis. Ann Rheum Dis 2007;66:1436-42.

339. Amin N, Duijn CM van, Aulchenko YS. A genomic background based method for association analysis in related individuals. PLoS ONE. 2007;2:e1274.

340. Arias-Vasquez A, Isaacs A, Aulchenko YS, Hofman A, Oostra BA, Breteler M, Duijn CM van. The cholesteryl ester transfer protein (CETP) gene and the risk of Alzheimer's disease. Neurogenetics 2007;8:189-93.

341. Arias-Vasquez A, Lau L de, Pardo L, Liu F, Feng BJ, Bertoli-Avella A, Isaacs A, Aulchenko Y, Hofman A, Oostra B, Breteler M, Duijn CM van. Relationship of the Ubiquilin 1 gene with Alzheimer's and Parkinson's disease and cognitive function. Neurosci Lett 2007;424:1-5.

342. Aulchenko YS, Ripke S, Isaacs A, Duijn CM van. GenABEL: an R library for genome-wide association analysis. Bioinformatics 2007;23:1294-6.

343. Aulchenko YS, Pullen J, Kloosterman WP, Yazdanpanah M, Hofman A, Vaessen N, Snijders PJ, Zubakov D, Mackay I, Olavesen M, Sidhu B, Smith VE, Carey A, Berezikov E, Uittenlinden AG, Plasterk RH, Oostra BA, Duijn CM van. LPIN2 is associated with type 2 diabetes, glucose metabolism and body composition. Diabetes 2007;56:3020-6.

344. Berends A, Bertoli-Avella A, Groot C de, Duijn CM van, Oostra B, Steegers E. STOX1 gene in pre-eclampsia and intrauterine growth restriction. BJOG 2007;114:1163-7.

345. Boccia S, Sayed-Tabatabaei FA, Persiani R, Gianfagna F, Rausei S, Arzani D, La Greca A, D'Ugo D, La Torre G, Duijn CM van, Ricciardi G. Polymorphisms in metabolic genes, their combination and interaction with tobacco smoke and alcohol consumption and risk of gastric cancer: a case-control study in an Italian population. BMC Cancer 2007;7:206.

346. Boccia S, Torre G la, Persiani R, D’Ugo D, Duijn CM van, Ricciardi G. A critical appraisal of epidemiological studies comes from basic knowledge: a readers guide to assess potential for biases. World J Emerg Surg 2007;2:7.

347. Boccia S, Lauretis A de, Gianfagna F, Duijn CM van, Ricciardi G. CYP2E1PstI/Rsal polymorphism and interaction with tobacco, alcohol and GSTs in gastric cancer susceptibility: a meta-analysis of the literature. Carcinogenesis 2007;28:101-6.

348. Boccia S, Gianfagna F, Persiani R, La Greca A, Arzani D, Rausei S, D’Ugo D, Magistrelli P, Villari P, Duijn CM van, Ricciardi G. Methylenetetrahydrofolate reductase C677T and A1298 C polymorphisms and susceptibility to gastric adenocarcinoma in an Italian population. Biomarkers 2007;12:635-44.

349. Boekhoorn SS, Vingerling JR, Uitterlinden AG, Meurs JB van, Duijn CM van, Pols HAP, Hofman A, Jong PT de. Estrogen receptor alpha gene polymorphisms associated with incident aging macula disorder. Invest Ophthalmol Vis Sci 2007;48:1012-7.

350. Coppus AMW, Fekkes D, Verhoeven WMA, Tuinier S, Egger JIM, Duijn CM van. Plasma amino acids and neopterin in healthy persons with Down’s syndrome. J Neural Transm 2007:11:1041-5.

351. Despriet DD, Klaver CC, Duijn CM van, Janssens AC. Predictive value of multiple genetic testing for age-related macular degeneration (Editorial). Arch Ophthalmol 2007;125:1270-1.

352. Dijk EJ van, Prins ND, Hofman A, Duijn CM van, Koudstaal PJ, Breteler MMB. Plasma beta amyloid and impaired CO(2)-induced cerebral vasomotor reactivity. Neurolbiol Aging 2007;28:707-12.

353. Gonzalez-Zuloeta Ladd AM, Liu F, Houben MP, Arias Vasquez A, Siemes C, Janssens AC, Coebergh JW, Hofman A, Janssen JA, Stricker BH, Duijn CM van. IGF-1 CA repeat variant and breast cancer risk in postmenopausal women. Eur J Cancer 2007;43:1718-22.

354. Gonzalez-Zuloeta Ladd AM, Arias Vasquez AA, Siemes C, Yazdanpanah M, Coebergh JW, Hofman A, Stricker BH, Duijn CM van. Differential Roles of Angiotensionogen and Angiotensin Receptor type 1 Polymorphisms in Breast Cancer Risk. Breast Cancer Res Treat 2007;101:299-304.

355. Gonzalez-Zuloeta Ladd AM, Arias Vasquez AA, Siemes C, Coebergh JW, Hofman A, Witteman J, Uitterlinden A, Stricker BH, Duijn CM van. Transforming-growth factor beta (1) Leu10Pro polymorphism and breast cancer morbidity. Eur J Cancer 2007;43:371-4.

356. Green A, Sanchez-Juan P, Ladogana A, Cuadrado-Corrales N, Sanchez-Valle R, Mitrova E, Stoeck K, Sklaviadis T, Kulczycki J, Heinemann U, Hess K, Slivarichova D, Saiz A, Calero M, Mellina V, Knight R, Duijn CM van, Zerr I. CSF analysis in patients with sporadic CJD and other transmissible spongiform encephalopathies. Eur J Neurol 2007;14:121-4.

357. Hofman A, Breteler MM, Duijn CM van, Krestin GP, Pols HA, Stricker BH, Tiemeier H, Uitterlinden AG, Vingerling JR, Witteman JC. The Rotterdam Study: objectives and design update. Eur J Epidemiol 2007;22:819-29.

358. Hoppenbrouwers IA, Cortes LM, Aulchenko YS, Sintnicolaas K, Njajou O, Snijders PJ, Oostra BA, Duijn CM van, Hintzen RQ. Familial clustering of multiple sclerosis in a Dutch genetic isolate. Mult Scler 2007;13:17-24.

359. Isaacs A, Sayed-Tabatabaei FA, Aulchenko YS, Zillikens MC, Sijbrands EJ, Schut AF, Rutten WP, Pols HA, Witteman JC, Oostra BA, Duijn CM van. Heritabilities, apolipoprotein E, and effects of inbreeding on plasma lipids in a genetically isolated population: The Erasmus Ruchpen Family Study. Eur J Epidemiol 2007;22:99-105.

360. Isaacs A, Sayed-Tabatabaei FA, Hofman A, Oostra BA, Klungel OH, Maitland-van der Zee AH, Stricker BHCh, Witteman JCM, Duijn CM van. The cholesteryl ester transfer protein I405V polymorphism is associated with increased high-density lipoprotein levels and decreased risk of myocardial infarction: the Rotterdam Study. Eur J Cardiovasc Prev Rehabil 2007;14:419-21.

361. Isaacs A, Aulchenko YS, Hofman A, Sijbrands EJ, Sayed-Tabatabaei FA, Klungel OH, Maitland-van der Zee AH, Stricker BH, Oostra BA, Witteman JC, Duijn CM van. Epistatic effect of cholesteryl ester transfer protein and hepatic lipase on serum high-density lipoprotein cholesterol levels. J Clin Endocrinol Metab 2007;92:2680-7.

362. Jaddoe VW, Bakker R, Duijn CM van, Heijden AJ van der, Lindemans J, Mackenbach JP, Moll HA, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, Hofman A. The Generation R Study Biobank: a resource for epidemiological studies in children and their parents. Eur J Epidemiol 2007;22:917-23.

363. Janssens AC, Moonesinghe R, Yang Q, Steyerberg EW, Duijn CM van, Khoury MJ. The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases. Genet Med 2007;9:528-35.

364. van Koolwijk LM, Despriet DD, Duijn CM van, Pardo Cortes LM, Vingerling JR, Aulchenko YS, Oostra BA, Klaver CC, Lemij HG. Genetic contributions to glaucoma: heritability of intraocular pressure, retinal nerve fiber layer thickness, and optic disc morphology. Invest Ophthalmol Vis Sci 2007;48:3669-76.

365. Liu F, Arias-Vasquez A, Sleegers K, Aulchenko YS, Kayser M, Sanchez-Juan P, Feng BJ, Bertoli-Avella AM, Swieten J van, Axenovich TI, Heutink P, Broeckhoven C van, Oostra BA, Duijn CM van. A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population. Am J Hum Genet 2007;81:17-31.

366. Mattace-Raso FU, Sie MP, Cammen TJ van der, Safar ME, Hofman A, Duijn CM van, Witteman JC. Insertion/deletion gene polymorphism of the angiotensin-converting enzyme and blood pressure changes in older adults. The Rotterdam study. J Hum Hypertens 2007;21:736-40.

367. Min JL, Meulenbelt I, Kloppenburg M, Duijn CM van, Slagboom PE. Mutation analysis of candidate genes within the 2q33.3 linkage area for familial early-onset generalised osteoarthritis. Eur J Hum Genet 2007;15:791-9.

368. Reitz C, den Heijer T, Duijn CM van, Hofman A, Breteler MM. Relation between smoking and risk of dementia and Alzheimer disease: the Rotterdam Study. Neurology 2007;69:998-1005.

369. Rijn MJE van, Schut AF, Aulchenko YS, Deinum J, Sayed-Tabatabaei FA, Yazdanpanah M, Isaacs A, Axenovich TI, Zorkoltseva IV, Zillikens MC, Pols HAP, Witteman JC, Oostra BA, Duijn CM van. Heritability of blood pressure traits and the genetic contribution to blood pressure variance explained by four blood-pressure related genes. J Hypertens 2007;25:565-70.

370. Rijn MJE, Bos MJ, Isaacs A, Yazdanpanah M, Arias-Vasquez A, Stricker BH, Klungel OH, Oostra BA, Koudstaal PJ, Witteman JC, Hofman A, Breteler MMB, Duijn CM van.

Polymorphisms of the renin-angiotensin system are associated with blood pressure, atherosclerosis and cerebral white matter pathology. J Neurol Neurosurg Psychiatry 2007;78:1083-7.

371. Sanchez-Juan P, Sanchez Valle R, Green A, Ladogana A, Cuadrado-Corrales N, Mitrova E, Stoeck K, Sklaviadis T, Kulczycki J, Hess K, Krasnianski A, Equestre M, Slivarichova D, Saiz A, Calero M, Pocchiari M, Knight R, Duijn CM van, Zerr I. Influence of timing on CSF tests value for Creutzfeldt-Jakob disease diagnosis. J Neurol 2007;25:901-6.

372. Sanchez-Juan P, Cousens SN, Will RG, Duijn CM van. Source of variant Creutzfeldt-Jakob disease outside United Kingdom. Emerg Infect Dis 2007;13:1166-9.

373. Sanchez-Juan P, Houben MPWA, Hoff JI, Jansen C, Sie MPS, Rijn MJE van, Ironside JW, Will RG, Duijn CM van, Rozemuller A. The first case of variant Creutzfeldt-Jakob disease in the Netherlands. J Neurol 2007;254:958-60.

374. Sánchez-Juan P, Bishop MT, Green A, Giannattasio C, Arias-Vasquez A, Poleggi A, Knight RS, Duijn CM van. No evidence for association between tau gene haplotypic variants and susceptibility to Creutzfeldt-Jakob disease. BMC Med Genet 2007;8:77.

375. Schelleman H, Klungel OH, Witteman JC, Breteler MM, Hofman A, Duijn CM van, Boer A de, Stricker BH. Diuretic-gene interaction and the risk of myocardial infarction and stroke. Pharmacogenomics J 2007;7:346-52.

376. Schelleman H, Klungel OH, Witteman JC, Breteler MMB, Yazdanpanah M, Danser AH, Hofman A, Duijn CM van, Boer A de, Stricker BH. Angiotensinogen M235T polymorphism and the risk of myocardial infarction and stroke among hypertensive patients on ACE-inhibitors or beta-blockers. Eur J Hum Genet 2007;15:478-84.

377. Schelleman H, Klungel OH, Witteman JC, Hofman A, Duijn CM van, Boer A de, Stricker BH. Pharmacogenetic interactions of three candidate gene polymorphisms with ACE-inhibitors or beta-blockers and the risk of atherosclerosis. Br J Clin Pharmacol 2007;64:57-66.

378. Sie MP, Mattace-Raso FU, Uitterlinden AG, Arp PP, Hofman A, Hoeks AP, Reneman RS, Asmar R, Duijn CM van, Witteman JC. TGF-beta1 polymorphisms and arterial stiffness; the Rotterdam Study. J Hum Hypertens 2007;21:413-7.

379. Silva MC, Janssens ACJW, Hofman A, Witteman JC, Duijn CM van. Cholesteryl ester transfer protein gene and coronary heart disease mortality: the Rotterdam study. J Am Geriatr Soc 2007;55:1483-4.

380. Sleegers K, Koning I de, Aulchenko YS, Rijn MJ van, Houben MP, Croes EA, Swieten JC van Oostra BA, Duijn CM van. Cerebrovascular risk factors do not contribute to genetic variance of cognitive function The ERF study. Neurobiol Aging 2007;28:735-41.

381. Sutedja NA, Sinke RJ, Vught PW van, Linden MW van der, Wokke JH, Duijn CM van, Njajou OT, Schouw YT van der, Veldink JH, Berg LH van den. The association between H63D mutations in HFE and amyotrophic lateral sclerosis in a Dutch population. Arch Neurol 2007;64:63-7.

382. Vleuten GM, Isaacs A, Hijmans A, Duijn CM van, Stalenhoef AF, Graaf J de. The involvement of upstream stimulatory factor 1 (USF1) in Dutch patients with familial combined hyperlipidemia. J Lipid Res 2007;48:193-200.

383. Vleuten GM, Isaacs A, Zeng WW, ter Avest E, Talmud PJ, Dallinga-Thie GM, Duijn CM van, Stalenhoef AF, Graaf J de. Haplotype analyses of the APOA5 gene in patients with familial combined hyperlipidemia. Biochim Biophys Acta 2007;1772:81-8.

384. Visser LE, Schaik RH van, Jan Danser AH, Hofman A, Witteman JC, Duijn CM van, Uitterlinden AG, Pols HA, Stricker BH. The risk of myocardial infarction in patients with reduced activity of cytochrome P450 2C9. Pharmacogenet Genomics 2007;17:473-9.

385. Yazdanpanah N, Rivadeneira F, Meurs JB van, Zillikens MC, Arp P, Hofman A, Duijn CM van, Pols HA, Uitterlinden AG. The -1997 G/T and Sp1 Polymorphisms in the Collagen Type I alpha1 (COLIA1) Gene in Relation to Changes in Femoral Neck Bone Mineral Density and the Risk of Fracture in the Elderly: The Rotterdam Study. Calcif Tissue Int 2007;81:18-25.

386. Yazdanpanah M, Aulchenko YS, Hofman A, Janssen JA, Sayed-Tabatabaei FA, Schaik RH van, Klungel OH, Stricker BH, Pols HA, Witteman JC, Lamberts SW, Oostra BA, Duijn CM van. Effects of the renin-angiotensin system genes and salt sensitivity genes on blood pressure and atherosclerosis in the total population and patients with type 2 diabetes. Diabetes 2007;56:1905-12.

2008

387. Arias-Vásquez A, Aulchenko YS, Isaacs A, Oosterhout A van, Sleegers K, Hofman A, Broeckhoven C van, Oostra BA, Breteler MMB, Duijn CM van. Cyclin-dependent kinase 5 is associated with risk for Alzheimer’s disease in a Dutch population-based study. J Neurol 2008;255:655-62.

388. Aulchenko YS, Hoppenbrouwers IA, Ramagopalan SV, Broer L, Jafar N, Hillert J, Link J, Lundström W, Greiner E, Sadovnick ED, Goossens D, Broeckhoven C van, Del-Favero J, Ebers GC, Oostra BA, Duijn CM van, Hintzen RQ. Genetic variation in the KIF1B locus determines susceptibility to multiple sclerosis. Nat Genet 2008; 40: 1402-3.

389. Berends AL, Groot CJ de, Sijbrands EJ, Sie MP, Benneheij SH, Pal R, Heydanus R, Oostra BA, Duijn CM van, Steegers EA. Shared constitutional risks for maternal vascular-related pregnancy complications and future cardiovascular disease. Hypertension 2008;51:1034-41.

390. Berends AL, Steegers EA, Isaacs A, Aulchenko YS, Liu F, Groot CJ de, Oostra BA, Duijn CM van. Familial aggregation of preeclampsia and intrauterine growth restriction in a genetically isolated population in The Netherlands. Eur J Hum Genet 2008; 16:1437-42.

391. Bilguvar K, Yasuno K, Niemelä M, Ruigrok YM, von Und Zu Fraunberg M, Duijn CM van, van den Berg LH, Mane S, Mason CE, Choi M, Gaál E, Bayri Y, Kolb L, Arlier Z, Ravuri S, Ronkainen A, Tajima A, Laakso A, Hata A, Kasuya H, Koivisto T, Rinne J, Ohman J, Breteler MM, Wijmenga C, State MW, Rinkel GJ, Hernesniemi J, Jääskeläinen JE, Palotie A, Inoue I, Lifton RP, Günel M. Susceptibility loci for intracranial aneurysm in European and Japanese populations. Nat Genet 2008; 40:1472-7.

392. Boccia S, Cadoni G, Sayed-Tabatabaei FA, Volante M, Arzani D, Lauretis A de, Cattel C, Almadori G, Duijn CM van, Paludetti G, Ricciardi G. CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and neck cancer. J Cancer Res Clin Oncol 2008;134:93-100.

393. Boccia S, Hung R, Ricciardi G, Gianfagna F, Ebert MP, Fang JY, Gao CM, Götze T, Graziano F, Lacasaña-Navarro M, Lin D, López-Carrillo L, Qiao YL, Shen H, Stolzenberg-Solomon R, Takezaki T, Weng YR, Zhang FF, Duijn CM van, Boffetta P, Taioli E. Meta- and pooled analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer risk: a huge-GSEC review. Am J Epidemiol 2008;167:505-16.

394. Boekhoorn SS, Isaacs A, Uitterlinden AG, Duijn CM van, Hofman A, Jong PT de, Vingerling JR. Polymorphisms in the vascular endothelial growth factor gene and risk of age-related macula degeneration: The Rotterdam Study. Ophthalmology 2008; 115: 1899-903.

395. Boogaard MJ van den, Costa D de, Krapels IP, Liu F, Duijn CM van, Sinke RJ, Lindhout D, Steegers-Theunissen RP. The MSX1 allele 4 homozygous child exposed to smoking at periconception is most sensitive in developing nonsyndromic orofacial clefts. Hum Genet 2008;124:525-34

396. Coppus AM, Evenhuis HM, Verberne GJ, Visser FE, Arias-Vasques A, Sayes-Tabatabaei FA, Vergeer-Drop J, Eikelenboom P, Gool WA van, Duijn CM van. The impact of apolipoprotein E on dementia in persons with Down’s syndrome. Neurobiol Aging 2008;29:825-35.

397. Coppus AW, Evenhuis HM, Verberne GJ, Visser FE, Oostra BA, Eikelenboom P, Gool PWA van, Janssens ACJW, Duijn CM van. Survival in elderly persons with Down’s syndrome. J Am Geriatr Soc 2008; 56:2311-6

398. Dehghan A, Hoek M van, Sijbrands EJ, Oostra BA, Hofman A, Duijn CM van, Witteman JCM. Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study. BMC Med 2008;6:30.

399. Dehghan A, Köttgen A, Yang Q, Hwang SJ, Kao LWH, Rivadeneira F, Boerwinkle E, Levy D, Hofman A, Astor BC, Benjamin EJ, Duijn CM van, Witteman JC, Coresh J, Fox CS. Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. Lancet 2008; 372:1953-61.

400. Driel LM van, Smedts HP, Helbing WA, Isaacs A, Lindemans J, Uitterlinden AG, Duijn CM van, Vries JH de, Steegers EA, Steegers-Theunissen RP. Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide. Eur Heart J 2008;29:1424-31.

401. Driel LM van, Verkleij-Hagoort AC, Jonge R de, Uitterlinden AG, Steegers EA, Duijn CM van, Steegers-Theunissen RP. Two MTHFR polymorphisms, maternal B-vitamin intake, and CHDs. Birth Defects Res A Clin Mol Teratol 2008;82:474-81.

402. Franzek EJ, Sprangers N, Janssens AC, Duijn CM van, Wetering BJ van de. Prenatal exposure to the 1944-45 Dutch ‘hunger winter’ and addiction later in life. Addiction 2008;103:433-8.

403. Geelhoed JJ, Mook-Kanamori DO, Witteman JCM, Hofman A, Duijn CM van, Moll HA, Steegers EA, Hokken-Koelega AC, Jaddoe VW. Variation in the IGF1 gene and growth in foetal life and infancy. The Generation R Study. Clin Endocrinol 2008;68:382-9.

404. Gianfagna F, Feo de E, Duijn CM van, Ricciardi G, Boccia S. A systematic review of meta-analyses on gene polymorphisms and gastric cancer risk Curr Genomics 2008; 9:361-74.

405. Gonzalez-Zuloeta Ladd AM, Vasquez AA, Rivadeneira F, Siemes C, Hofman A, Stricker BH, Pols HA, Uitterlinden AG, Duijn CM van. Estrogen receptor alpha polymorphisms and postmenopausal breast cancer risk. Breast Cancer Res Treat 2008;107:415-9.

406. Henneman P, Aulchenko YS, Frants RR, Duijk KW van, Oostra BA, Duijn CM van. Prevalence and heritability of the metabolic syndrome and its individual components in a Dutch isolate: the Erasmus Rucphen Family study. J Med Genet 2008;45:572-7.

407. Ho L, Boekhoorn SS, Liana, Duijn CM van, Uitterlinden AG, Hofman A, de Jong PT, Stijnen T, Vingerling JR. Cataract surgery and the risk of aging macula disorder: the rotterdam study. Invest Ophthalmol Vis Sci 2008;49:4795-800.

408. Hoek M van, Deghan A, Witteman JC, Duijn CM van, Uitterlinden AG, Oostra BA, Hofman A, Sijbrands EJ, Janssens ACJW. Predicting type 2 diabetes based on polymorphisms from genome wide association studies: a population-based study. Diabetes 2008; 57:3122-8.

409. Hoppenbrouwers IA, Liu F, Aulchenko YS, Ebers GC, Oostra BA, Duijn CM van, Hintzen RQ. Maternal transmission of multiple sclerosis in a Dutch population. Arch Neurol 2008;65:345-8.

410. Hoppenbrouwers IA, Aulchenko YS, Ebers GC, Ramagopalan SV, Oostra BA, Duijn CM van, Hintzen RQ. EVI5 is a risk gene for multiple sclerosis. Genes Immun 2008;9:334-7.

411. Houten VA van, Mook-Kanamori DO, Osch-Gevers L van, Steegers EA, Hofman A, Moll HA, Duijn CM van, Helbing WA, Hokken-Koelega AC, Jaddoe VW. A variant of the IGF-I gene is associated with blood pressure but not with left heart dimensions at the age of 2 years: the Generation R Study. Eur J Endocrinol 2008;159:209-16.

412. International Multiple Sclerosis Genetics Consortium (IMSGC).. Booth D, Heard R, Stewart G, Goris A, Dobosi R, Dubois B, Oturai A, Soendergaard HB, Sellebjerg F, Saarela J, Leppä V, Palotie A, Peltonen L, Fontaine B, Cournu-Rebeix I, Cierget-Darpoux F, Babron MC, Weber F, Holsboer F, Müller-Mysok B, Rieckmann P, Kroner A, Graham C, Vandenbroeck K, Hawkins S, D’ Alfonso S, Bergamaschi L, Naldi P, Guerini FR, Salvetti M, Galimberti D, Hintzen R, Duijn van CM, Lorentzen AR, Celius EG, Harbo HF, Spurkland A, Cucca F, Marrosu MG, Comabella M, Montalban X, Villoslada P, Olsson T, Kockum I, Hillert J, Ban M, Walton A, Sawcer S, Compston A, Hawkins C, Mihalova T, Robertson N, Ingram G, De Jager PL, Hafler DA, Rioux J, Daly M, Barcellos L, Ivinson A, Pericak-Vance M, Oksenberg J, Hauser SL, McCauley J, Sexton D, Haines J. Refining genetic associations in multiple sclerosis. Lancet Neurol 2008;7:567-9.

413. Jaddoe VW, Duijn CM van, van der Heijden AJ, Mackenbach JP, Moll HA, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, Hofman A.Eur J Epidemiol. The Generation R Study: design and cohort update until the age of 4 years. Eur J Epidemiol 2008; 23:801-11

414. Janssens ACJW, Gwinn M, Bradley LA, Oostra BA, Duijn CM van, Khoury MJ. A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions. Am J Hum Genet 2008;82:593-9.

415. Janssens ACJW, Duijn CM van. Genome-based prediction of common diseases: advances and prospects. Hum Mol Genet 2008;17:166-73.

416. Janssens ACJW, Duijn CM van. Five genetic variants associated with prostate cancer. N Engl J Med 2008;358:2738-9.

417. Kayser M, Liu F, Janssens ACJW, Rivadeneira F, Lao O, Duijn K van, Vermeulen M, Arp P, Jhamai MM, IIcken WF van, Dunnen JT den, Heath S, Zelenika D, Despriet DD, Klaver CC, Vingerling JR, Jong PT de, Hofman A, Aulchenko YS, Uitterlinden AG, Oostra BA, Duijn CM van. Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene. Am J Hum Genet 2008;82:411-23.

418. Knaap R van der, Siemes C, Coebergh JW, Duijn CM van, Hofman A, Stricker BH. Renin-agiotensin system inhibitors, angiotensin I-converting enzyme gene insertion/deletion polymorphism, and cancer: the Rotterdam Study. Cancer 2008;112:748-57.

419. Langdahl BL, Uitterlinden AG, Ralston SH, Trikalinos TA, Balcells S, Brandi ML, Scollen S, Lips P, Lorenc R, Obermayer-Pietsch B, Reid DM, Armas JB, Arp PP, Bassiti A, Bustamante M, Husted LB, Carey AH, Pérez Cano R, Dobnig H, Dunning AM, Fahrleitner-Pammer A, Falchetti A, Karczmarewicz E, Kruk M, Leeuwen JP van, Masi L, Meurs JB van, Mangion J, McGuigan FE, Mellibovsky L, Mosekilde L, Nogués X, Pols HA, Reeve J, Renner W, Rivadeneira F, Schoor NM van, Ioannidis JP; APOSS investigators; DOPS investigators; EPOS investigators; EPOLOS investigators; FAMOS investigators; LASA investigators; ERGO investigators; GENOMOS Study. Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study. Bone 2008;42:969-81.

420. Liu F, Kirichenko A, Axenovich TI, Duijn CM van, Aulchenko YS. An approach for cutting large and complex pedigrees for linkage analysis. Eur J Hum Genet 2008;16:854-60.

421. López-León S, Janssens ACJW, Tiemeier H, Hofman A, Aulchenko YS, Snijders PJ, Claes S, Oostra BA, Duijn CM van. Angiotensinogen M235T polymorphism and symptoms of depression in a population-based study and a family-based study. Psychiatr Genet 2008;18:162-6.

422. Lopez-Leon S, Janssens AC, Gonzalez-Zuloeta Ladd AM, Del-Favero J, Claes SJ, Oostra BA, Duijn CM van. Meta-analyses of genetic studies on major depressive disorder. Mol Psychiatry 2008;13:772-85.

423. Meulenbelt I, Min JL, Bos S, Riyazi N, Houwing-Duistermaat JJ, Wijk HJ van der, Kroon HM, Nakajima M, Ikegawa S, Uitterlinden AG, Meurs JB van, Deure WM van der, Visser TJ, Seymour AB, Lakenberg N, Breggen R van der, Kremer D, Duijn CM van, Kloppenburg

M, Loughlin J, Slagboom PE. Identification of DIO2 as new susceptibility locus for symptomatic osteoarthritis. Hum Mol Genet 2008;17:1867-75.

424. Meurs JB van, Trikalinos TA, Ralston SH, Balcells S, Brandi ML, Brixen K, Kiel DP, Langdahl BL, Lips P, Ljunggren O, Lorenc R, Obermayer-Pietsch B, Ohlsson C, Pettersson U, Reid DM, Rousseau F, Scollen S, Hul W van, Agueda L, Akesson K, Benevolenskaya LI, Ferrari SL, Hallmans G, Hofman A, Husted LB, Kruk M, Kaptoge S, Karasik D, Karlsson MK, Lorentzon M, Masi L, McGuigan FE, Mellström D, Mosekilde L, Nogues X, Pols HA, Reeve J, Renner W, Rivadeneira F, Schoor NM van, Weber K, Ioannidis JP, Uitterlinden AG, GENOMOS Study. Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA 2008;299:1277-90.

425. Pardo Silva MC, Janssens AC, Hofman A, Witteman JC, Duijn CM van. Apoliprotein E gene is related to mortality only in normal weight individuals: the Rotterdam Study. Eur J Epidemiol 2008;23:135-42.

426. Peters BJ, Maitland-van der Zee AH, Stricker BH, Wieren-de Wijer DB van, Boer A de, Kroon AA, Leeuw PW de, Schiffers P, Janssen RG, Duijn CM van, Klungel OH. Effectiveness of statins in the reduction of the risk of myocardial infarction is modified by the GNB3 C825T variant. Pharmacogenet Genomics 2008;18:631-636.

427. Schelleman H, Klungel OH, Witteman JC, Breteler MM, Hofman A, Duijn CM van Boer A de, Stricker BH. Interaction between polymorphisms in the renin-angiotensin-system and angiotensin-converting enzyme inhibitor or beta-blocker use and the risk of myocardial infarction and stroke. Pharmacogenomics J 2008;8:400-7.

428. Sie MP, Mattace-Raso FU, Uitterlinden AG, Arp PP, Hofman A, Pols HA, Hoeks AP, Reneman RS, Asmar R, Duijn CM van, Witteman JC. The interleukin-6-174 G/C promoter polymorphism and arterial stiffness; the Rotterdam Study.Vasc Health Risk Manag 2008;4:863-9.

429. Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, Grosshenning A, Schillert A, Teumer A, schmidt R, Kathiresan S, Lumley T, Aulchenko YS, König IR, Zeller T, Homuth G, Struchalin M, Aragam J, Bis JC, Rivadeneira F, erdmann J, Schnabel RB, Dörr M. Zweiker R, Lind L, Rodeheffer RJ, Greiser KH, Levy D, Haritunians T, Deckers JW, Stritzke J, Lackner KJ, Völker U, Ingelsson E, Kullo I, Haerting J, O’donnel CJ, Heckbert SR, Stricker BH, Ziegler A, Reffelman T, Redfield MM, Werdan K, Mitchell GF, Rice K, Arnett DK, Hofman A, Gottdiener JS, Uitterlinden AG, Meitinger T, Blettner M, Friedrich N, Wang TJ, Psaty BM, Duijn CM van, Wichmann HE, MunzelTF, Kroemer HK, Benjamin EJ, Rotter JI, Witteman JC, Schunkert H, Schmidt H, Völzke H, Blankenberg S. Genetic Variants Associated with cardiac Structure and Function: A Meta-analysis and Replication of Genome-wide Association Data. JAMA 2009;302:168-178.

430. Willemse-van Son AH, Ribbers GM, Hop WC, Duijn CM van, Stam HJ. Association between apolipoprotein-epsilon4 and long-term outcome after traumatic brain injury. J Neurol Neurosurg Psychiatry 2008;79:426-30.

431. Zillikens MC, Yazdanpanah M, Pardo LM, Rivadeneira F, Aulchenko YS, Oostra BA, Uitterlinden AG, Pols HA, Duijn CM van. Sex-specific genetic effects influence variation in body composition. Diabetologia 2008;51:2233-41.

2009

432. Alizadeh BZ, Njajou OT, Millan MR, Hofman A, Breteler MM, Duijn CM van. HFE variants, APOE and Alzheimer's disease: Findings from the population-based Rotterdam Study. Neurobiol Aging 2009; 30:330-2.

433. Amin N, Aulchenko YS, Dekker M.C, Ferdinand RF, Spreeken A van, Temmink AH, Verhulst FC, Oostra BA, Duijn CM van. Suggestive linkage of ADHD to chromosome 18q22 in a young genetically isolated Dutch population. Eur J Hum Genet 2009;17:958-66.

434. Amin N, Duijn CM van, Janssens AC. Genetic Scoring Analysis: a way forward in Genome Wide Association Studies? Eur J Epidemiol. 2009;24:585-7.

435. Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, Penninx BW, Janssens AC, Wilson JF, Spector T, Martin NG, Pedersen NL, Kyvik KO, Kaprio J, Hofman A, Freimer NB, Jarvelin MR, Gyllensten U, Campbell H, Rudan I, Johansson A, Marroni F, Hayward C, Vitart V, Jonasson I, Pattaro C, Wright A, Hastie N, Pichler I, Hicks AA, Falchi M, Willemsen G, Hottenga JJ, de Geus EJ, Montgomery GW, Whitfield J, Magnusson P, Saharinen J, Perola M, Silander K, Isaacs A, Sijbrands EJ, Uitterlinden AG, Witteman JC, Oostra BA, Elliott P, Ruokonen A, Sabatti C, Gieger C, Meitinger T, Kronenberg F, Döring A, Wichmann HE, Smit JH, McCarthy MI, Duijn CM van, Peltonen L; for the ENGAGE Consortium. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet 2009; 41:47-55.

436. Aulchenko YS, Struchalin MV, Belonogova NM, Axenovich TI, Weedon MN, Hofman A, Uitterlinden AG, Kayser M, Oostra BA, Duijn CM van, Janssens AC, Borodin PM. Predicting human height by Victorian and genomic methods. Eur J Hum Genet 2009;17:1070-5.

437. Axenovich TI, Zorkoltseva IV, Belonogova NM, Struchalin MV, Kirichenko AV, Kayser M, Oostra BA, Duijn CM van, Aulchenko YS. Linkage analysis of adult height in a large pedigree from a Dutch genetically isolated population. Hum Genet 2009;126:457-71.

438. Benjamin EJ, Rice KM, Arking DE, Pfeufer A, van Noord C, Smith AV, Schnabel RB, Bis JC, Boerwinkle E, Sinner MF, Dehghan A, Lubitz SA, D'Agostino Sr RB, Lumley T, Ehret GB, Heeringa J, Aspelund T, Newton-Cheh C, Larson MG, Marciante KD, Soliman EZ, Rivadeneira F, Wang TJ, Eiríksdottir G, Levy D, Psaty BM, Li M, Chamberlain AM, Hofman A, Vasan RS, Harris TB, Rotter JI, Kao WH, Agarwal SK, Stricker BH, Wang K, Launer LJ, Smith NL, Chakravarti A, Uitterlinden AG, Wolf PA, Sotoodehnia N, Köttgen A, Duijn CM van, Meitinger T, Mueller M, Perz S, Steinbeck G, Wichmann HE, Lunetta KL, Heckbert SR, Gudnason V, Alonso A, Kääb S, Ellinor PT, Witteman JC. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet 2009;41:897-81.

439. Berends AL, Zillikens MC, Groot CJM de, Rivadeneira F, Oostra BA, Duijn CM van, Steegers. Body composition by dual energy-X-ray absorptiometry in women with previous preeclampsia or small for gestational age offspring. BJOG 2009;116:442-51.

440. Bliek BJ, Schaik RH van , Heiden IP van der, Sayed-Tabatabaei FA, Duijn CM van , Steegers EA, Steegers-Theunissen RP; Eurocran Gene-Environment Interaction Group. Maternal

medication use, carriership of the ABCB1 3435C > T polymorphism and the risk of a child with cleft lip with or without cleft palate. Am J Med Genet A 2009;149A:2088-92.

441. Boccia S, Boffetta P, Brennan P, Ricciardi G, Gianfagna F, Matsuo K, Duijn CM van, Hung RJ. Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer. Cancer Lett 2009;273:55-61.

442. Boccia S, Hashibe M, Gallì P, De Feo E, Asakage T, Hashimoto T, Hiraki A, Katoh T, Nomura T, Yokoyama A, Duijn CM van, Ricciardi G, Boffetta P. Aldehyde dehydrogenase 2 and head and neck cancer: a meta-analysis implementing a Mendelian randomization approach. Cancer Epidemiol Biomarkers Prev 2009;18:248-54.

443. Brugts JJ, de Maat MP, Boersma E, Witteman JC, Duijn CM van, Uitterlinden AG, Bertrand M, Remme W, Fox K, Ferrari R, Danser AH, Simoons ML; EUROPA-PERGENE investigators. Cardiovasc Drugs Ther 2009;23:171-81.

444. Choy WC, López-León S, Aulchenko YS, Mackenbach JP, Oostra BA, Duijn CM van, Janssens AC. Role of shared genetic and environmental factors in symptoms of depression and body composition. Psychiatr Genet 2009;19:32-8.

445. Combarros O, Duijn CM van , Hammond N, Belbin O, Arias-Vásquez A, Cortina-Borja M, Lehmann MG, Aulchenko YS, Schuur M, Kölsch H, Heun R, Wilcock GK, Brown K, Kehoe PG, Harrison R, Coto E, Alvarez V, Deloukas P, Mateo I, Gwilliam R, Morgan K, Warden DR, Smith AD, Lehmann DJ. Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease. J Neuroinflammation 2009;23;6:22.

446. Coppus AM, Fekkes D, Verhoeven WM, Evenhuis HM, Duijn CM van. Neopterin and the risk of dementia in persons with Down syndrome. Neurosci Lett 2009;17;458:60-4.

447. De Feo E, Persiani R, La Greca A, Amore R, Arzani D, Rausei S, D’Ugo D, Magistrelli P, Duijn CM van, Ricciardi G, Boccia S. A case – control study on the effect of p53 and p73 gene polymorphisms on gastric cancer risk and progression. Mutat Res 2009;675:60-5.

448. Dehghan A; Yang Q; Peters A, Basu S, Bis JC, Rudnicka AR, Kavousi M, Chen MH, Baumert J, Lowe GDO, McKnight B, Tang W, Maat de M, Larson MG, Eyhermendy S, McArdle WL, Lumley T, Pankow JS, Hofman, A, Massaro JM, Rivadeneira F, Kolz M, Taylor KD, Duijn CM van, Kathiresan S, Illig T, Aulchenko IS, Volcik KA, Johnson AD, Uitterlinden AG, Tofler GH, Gieger C, Wellcome Trust Case Control Consortium, Psaty BM, Couper DJ, Boerwinkle E, Koenig W, O'Donnell CJ, Witteman JC, Strachan DP, Smith NL, Folsom AR, Association of Novel Genetic Loci with Circulating Fibrinogen level; A Genome-Wide Association Study in Six Population-Based Cohorts. Circulation Genetics 2009;2:125-133.

449. Despriet DD, Duijn CM van, Oostra BA, Uitterlinden AG, Hofman A, Wright AF, ten Brink JB, Bakker A, de Jong PT, Vingerling JR, Bergen AA, Klaver CC. Complement component C3 and risk of age-related macular degeneration. Ophthalmology 2009;116:474-480.e2.

450. Duijts L, Bakker-Jonges LE, Mook-Kanamori DO, Labout JA, Hofman A, Duijn CM van, Dongen JJ van, Hooijkaas H, Moll HA, Jaddoe VW. Variation in the insulin-like growth

factor-1 gene is associated with lymphocyte subset counts in neonates. The Generation R Study. Clin Endocrinol 2009;70:53-59.

451. Eijgelsheim M, Aarnoudse AL, Rivadeneira F, Kors JA, Witteman JC, Hofman A, Duijn CM van, Uitterlinden AG, Stricker BH. Identification of a common variant at the NOS1AP locus strongly associated to QT - interval duration. Hum Mol Genet 2009;15;18:347-57.

452. Estrada K, Krawczak M, Schreiber S, van Duijn K, Stolk L, van Meurs JB, Liu F, Penninx BW, Smit JH, Vogelzangs N, Hottenga JJ, Willemsen G, de Geus EJ, Lorentzon M, von Eller-Eberstein H, Lips P, Schoor N, Pop V, de Keijzer J, Hofman A, Aulchenko YS, Oostra BA, Ohlsson C, Boomsma DI, Uitterlinden AG, Duijn CM van, Rivadeneira F, Kayser M. A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. Hum Mol Genet 2009;15;18:3516-24.

453. Feo E De, Persiani R, La Greca A, Amore R, Arzani D, Rausei S, D'Ugo D, Magistrelli P, Duijn CM van, Ricciardi G, Boccia S. A case-control study on the effect of p53 and p73 gene polymorphisms on gastric cancer risk and progression. Mutat Res 2009;30;675:60-5.

454. Gianfagna F, De Feo E, Duijn CM van, Ricciardi G, Boccia S. A systematic review of meta-analyses on gene polymorphisms and gastric cancer risk. Curr Genomics 2008;9:361-74.

455. Heard-Costa NL, Zillikens MC, Monda KL, Johansson A, Harris TB, Fu M, Haritunians T, Feitosa MF, Aspelund T, Eiriksdottir G, Garcia M, Launer LJ, Smith AV, Mitchell BD, McArdle PF, Shuldiner AR, Bielinski SJ, Boerwinkle E, Brancati F, Demerath EW, Pankow JS, Arnold AM, Chen YD, Glazer NL, McKnight B, Psaty BM, Rotter JI, Amin N, Campbell H, Gyllensten U, Pattaro C, Pramstaller PP, Rudan I, Struchalin M, Vitart V, Gao X, Kraja A, Province MA, Zhang Q, Atwood LD, Dupuis J, Hirschhorn JN, Jaquish CE, O'Donnell CJ, Vasan RS, White CC, Aulchenko YS, Estrada K, Hofman A, Rivadeneira F, Uitterlinden AG, Witteman JC, Oostra BA, Kaplan RC, Gudnason V, O'Connell JR, Borecki IB, Duijn CM van, Cupples LA, Fox CS, North KE. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet 2009;5:e1000539.

456. Henneman P, van der Sman-de Beer F, Moghaddam PH, Huijts P, Stalenhoef AF, Kastelein JJ, Duijn CM van, Havekes LM, Frants RR, van Dijk KW, Smelt AH. The expression of type III hyperlipoproteinemia: involvement of lipolysis genes. Eur J Hum Genet 2009;17:620-8.

457. Hicks AA, Pramstaller PP, Johansson A, Vitart V, Rudan I, Ugocsai P, Aulchenko Y, Franklin CS, Liebisch G, Erdmann J, Jonasson I, Zorkoltseva IV, Pattaro C, Hayward C, Isaacs A, Hengstenberg C, Campbell S, Gnewuch C, Janssens AC, Kirichenko AV, König IR, Marroni F, Polasek O, Demirkan A, Kolcic I, Schwienbacher C, Igl W, Biloglav Z, Witteman JC, Pichler I, Zaboli G, Axenovich TI, Peters A, Schreiber S, Wichmann HE, Schunkert H, Hastie N, Oostra BA, Wild SH, Meitinger T, Gyllensten U, van Duijn CM van, Wilson JF, Wright A, Schmitz G, Campbell H. Genetic determinants of circulating sphingolipid concentrations in European populations. PLoS Genet 2009;5:e1000672.

458. Hofman A, Breteler MM, Duijn CM van, Janssen HL, Krestin GP, Kuipers EJ, Stricker BH, Tiemeier H, Uitterlinden AG, Vingerling JR, Witteman JC. The Rotterdam Study: 2010 objectives and design update. Eur J Epidemiol 2009;24:553-72.

459. Ikram MA, Seshadri S, Bis JC, Fornage M, Destefano AL, Aulchenko YS, Debette S, Lumley T, Folsom AR, van den Herik EG, Bos MJ, Beiser A, Cushman M, Launer LJ, Shahar E, Struchalin M, Du Y, Glazer NL, Rosamond WD, Rivadeneira F, Kelly-Hayes M, Lopez OL, Coresh J, Hofman A, Decarli C, Heckbert SR, Koudstaal PJ, Yang Q, Smith NL, Kase CS, Rice K, Haritunians T, Roks G, de Kort PL, Taylor KD, de Lau LM, Oostra BA, Uitterlinden AG, Rotter JI, Boerwinkle E, Psaty BM, Mosley TH, Duijn CM van, Breteler MM, Longstreth WT Jr, Wolf PA. Genomewide Association Studies of Stroke. N Engl J Med 2009;23;360:1718-28.

460. Ikram MA, Liu F, Oostra BA, Hofman A, Duijn CM van, Breteler MM. The GAB2 Gene and the Risk of Alzheimer's Disease: Replication and Meta-Analysis. Biol Psychiatry 2009;1;65:995-9.

461. Jansen C, Schuur M, Spliet WG, van Gool WA, Duijn CM van , Rozemuller AJ. Eleven years of autopsy on account of Creutzfeldt-Jakob disease in the Netherlands. Ned Tijdschr Geneeskd. 2009;153. pii: Ned Tijdschr Geneesk.2009;153:A172.

462. Janssens AC, Gonzáles-Zuloeta Ladd AM, López- Léon S, Ioannidis JP, Oostra BA, Khoury MJ, Duijn CM van. An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses. Genet Med 2009;11:153-162.

463. Johansson A, Marroni F, Hayward C, Franklin CS, Kirichenko AV, Jonasson I, Hicks AA, Vitart V, Isaacs A, Axenovich T, Campbell S, Dunlop MG, Floyd J, Hastie N, Hofman A, Knott S, Kolcic I, Pichler I, Polasek O, Rivadeneira F, Tenesa A, Uitterlinden AG, Wild SH, Zorkoltseva IV, Meitinger T, Wilson JF, Rudan I, Campbell H, Pattaro C, Pramstaller P, Oostra BA, Wright AF, Duijn CM van, Aulchenko YS, Gyllensten U; on behalf of the EUROSPAN Consortium. Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis. Hum Mol Genet 2009;18:373-380.

464. Johnson AD, Kavousi M, Smith AV, Chen MH, Dehghan A, Aspelund T, Lin JP, Duijn CM van, Harris TB, Cupples LA, Uitterlinden AG, Launer L, Hofman A, Rivadeneira F, Stricker B, Yang Q, O'Donnell CJ, Gudnason V, Witteman JC. Genome-wide association meta-analysis for total serum bilirubin levels. Hum Mol Genet 2009;15;18:2700-10.

i. Multiple loci associated with indices of renal function and chronic kidney disease.

ii. Anna Köttgen, Nicole L Glazer, Abbas Dehghan, Shih-Jen Hwang,iii. Ronit Katz Man Li Qiong Yang Vilmundur Gudnason, Lenore Jiv. Launer(21), Tamara B Harris(21), Albert V Smith(19), Dan E Arking(7), Brad C

Astor(1), Eric Boerwinkle(8), Georg B Ehret(7),(23), Ingo Ruczinski(9), Robert B Scharpf(9), Yii-Der Ida Chen(10), Ian H de Boer(11), Talin Haritunians(10), Thomas Lumley(5), Mark Sarnak(12), David Siscovick(13), Emelia J Benjamin(14), Daniel Levy(4), Ashish Upadhyay(15), Yurii S Aulchenko(3), Albert Hofman(3), Fernando Rivadeneira(16), André G Uitterlinden(16), Cornelia M van Duijn(3), Daniel Chasman(22), Guillaume Paré(22), Paul M Ridker(22), WH Linda Kao(1), Jacqueline C Witteman(3),(24),**, Josef Coresh(1),(9),**, Michael G,Shlipak(17),**, and Caroline S Fox(4),(18),**

465. Koolwijk LM van, Despriet DD, Duijn CM van , Oostra BA, Swieten JC van, de Koning I van, Klaver CC, Lemij HG. Association of cognitive functioning with retinal nerve fiber layer thickness. Invest Ophthalmol Vis Sci 2009;50:4576-80.

466. Ladogana A, Sanchez-Juan P, Mitrová E, Green A, Cuadrado-Corrales N, Sánchez-Valle R, Koscova S, Aguzzi A, Sklaviadis T, Kulczycki J, Gawinecka J, Saiz A, Calero M, Duijn CM van, Pocchiari M, Knight R, Zerr I. Cerebrospinal fluid biomarkers in human transmissible spogform encephalopathies. J Neurol 2009;256:1620-8.

467. Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, Aulchenko YS, Chambers JC, Drong A, Luan J, Lyon HN, Rivadeneira F, Sanna S, Timpson NJ, Zillikens MC, Zhao JH, Almgren P, Bandinelli S, Bennett AJ, Bergman RN, Bonnycastle LL, Bumpstead SJ, Chanock SJ, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Doney AS, Ebrahim S, Elliott P, Erdos MR, Estrada K, Ferrucci L, Fischer G, Forouhi NG, Gieger C, Grallert H, Groves CJ, Grundy S, Guiducci C, Hadley D, Hamsten A, Havulinna AS, Hofman A, Holle R, Holloway JW, Illig T, Isomaa B, Jacobs LC, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Lathrop GM, Lawlor DA, Mangino M, McArdle WL, Meitinger T, Morken MA, Morris AP, Munroe P, Narisu N, Nordström A, Nordström P, Oostra BA, Palmer CN, Payne F, Peden JF, Prokopenko I, Renström F, Ruokonen A, Salomaa V, Sandhu MS, Scott LJ, Scuteri A, Silander K, Song K, Yuan X, Stringham HM, Swift AJ, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Walters GB, Weedon MN; Wellcome Trust Case Control Consortium, Witteman JC, Zhang C, Zhang W, Caulfield MJ, Collins FS, Davey Smith G, Day IN, Franks PW, Hattersley AT, Hu FB, Jarvelin MR, Kong A, Kooner JS, Laakso M, Lakatta E, Mooser V, Morris AD, Peltonen L, Samani NJ, Spector TD, Strachan DP, Tanaka T, Tuomilehto J, Uitterlinden AG, Duijn CM van, Wareham NJ, Hugh Watkins; Procardis Consortia, Waterworth DM, Boehnke M, Deloukas P, Groop L, Hunter DJ, Thorsteinsdottir U, Schlessinger D, Wichmann HE, Frayling TM, Abecasis GR, Hirschhorn JN, Loos RJ, Stefansson K, Mohlke KL, Barroso I, McCarthy MI; Giant Consortium. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009;5:e1000508.

468. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, Duijn CM van, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N. STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE Statement. Ann Intern Med 2009;3;150:206-15.

469. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, Duijn CM van, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N. STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement. PLoS Med 2009;3;6:e22.

470. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J,Duijn CM van, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N.

Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement. Eur J Epidemiol 2009;24:37-55.

471. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, Duijn CM van, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N. Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement. Hum Genet 2009;125:131-51.

472. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, Duijn CM van, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart AF, Birkett N. Strengthening the reporting of genetic association studies (STREGA)-an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement. J Clin Epidemiol 2009;62:597-608.e4.

473. Little J, Higgins JP, Ioannidis JP, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B, Davey-Smith G, Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M, Golding J, Duijn CM van, McLaughlin J, Paterson A, Wells G, Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart AF, Birkett N. Strengthening the reporting of genetic association studies (STREGA)-an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement. Eur J Clin Invest 2009;39:247-66.

474. Liu F, ikram MA, Janssens AC, Schuur M, de Koning I, Isaacs A, Struchalin M, Uitterlinden AG, den Dunnen JT, Sleegers K, Bettens K, Van Broeckhoven C, van Swieten J, Hofman A, Oostra BA, Aulchenko YS, Breteler MM, Duijn CM van. A Study of the SORL1 Gene in Alzheimer’s Disease and Cognitive Function. J Alzeheimers Dis 2009;18:51-64.

475. López-León S, Choy WC, Aulchenko YS, Claes SJ, Oostra BA, Mackenbach JP, Duijn CM van, Janssens AC. Genetic factors influence the clustering of depression among individuals with lower socioeconomic status. PloS One 2009;4:e5069.

476. Mihaescu R, van Hoek M, Sijbrands EJ, Uitterlinden AG, Witteman JC, Hofman A, Duijn CM van, Janssens AC. Evaluation of risk prediction updates from commercial genome-wide scans. Genet Med 2009;11:588-94.

477. Mook-Kanamori DO, Steegers EA, Uitterlinden AG, Moll HA, Duijn CM van, Hofman A, Jaddoe VW. Breast-feeding modifies the association of PPARgamma2 polymorphism Pro12ala with growth in early life: The Generation R Study. Diabetes 2009;58:992-8.

478. Mook-Kanamori DO, de Kort SW, Duijn CM van, Uitterlinden AG, Hofman A, Moll HA, Steegers EA, Hokken-Koelega AC, Jaddoe VW. Type 2 diabetes gene TCF7L2 polymorphism is not associated with fetal and postnatal growth in two birth cohort studies. BMC Med Genet 2009;17;10:67.

479. Mook-Kanamori DO, de Kort SW,Duijn CM van, Uitterlinden AG, Hofman A, Moll HA, Steegers EA, Hokken-Koelega AC, Jaddoe VW. BMC Med Genet 2009;10:67.

480. Omidvar M, Stolk L, Uitterlinden AG, Hofman A, Duijn CM van, Tiemeier H. The effect of catechol-O-methyltransferase Met/Val functional polymorphism on smoking cessation: retrospective and prospective analyses in a cohort study. Pharmacogenet Genomics 2009;19:45-51.

481. Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lussenko V, chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliot P, Freimer N, Gateva V, Herder C, Hofman A, Huhges TE, Hunt S, Illig T, Inouye M, Isomaa B, Jonhnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Moriss AD, Naitza S, Orrù M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp S, Sijbrands E, Smit JH, Song K, Steinhorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altschuler D, Vollenweider P, Jarvelin MR, Lakatta E, Waeber G, Fox CS, Peltonen L, Groop LC, Mooster V, Cupples LA, Thorsteinsdottir U, Boehke M, Barroso I, Duijn CM van, Dupuis J, Watanabe RM, Stefansson K, McCarthy MI, Wareham NJ, Meigs JB, Abecasis GR. for the MAGIC investigators Variants in the melatonin receptor 1B gene (MTNR1B) influence fasting glucose levels. Nat Genet 2009;41:77-81.

482. Ripatti S, Becker T, Bickeböller H, Dominicus A, Fischer C, Humphreys K, Jonasdottir G, Moreau Y, Olsson M, Ploner A, Sheehan N, Steen K van, Baur M, Duijn CM van, Palmgren J. GENESTAT: an information portal for design and analysis of genetic association studies. Eur J Hum Genet 2009;17:533-6.

483. Schuur M, Jansen C, Rozemuller AJ, van Gool WA, Duijn CM van. Human spongiform encephalopathies in the Netherlands. Ned Tijdschr Geneeskd. 2009;153. pii: Ned Tijdschr Geneesk 2009;153:A173.

484. Sie MP, Isaacs A, de Maat MP, Mattace-Raso FU, Uitterlinden AG, Kardys I, Hofman A, Hoeks AP, Reneman RS, Duijn CM van, Witteman JC. Genetic variation in the fibrinogen-alpha and fibrinogen-gamma genes in relation to arterial stiffness: the Rotterdam Study. J Hypertens 2009;27:1392-8.

485. Siemes C, Eijgelsheim M, Dieleman JP, van Schaik RH, Uitterlinden AG, Duijn CM van, Hofman A, Coebergh JW, Stricker BH, Visser LE. No modification of the beneficial effect of NSAIDs on colorectal cancer by CYP2C9 genotype. Neth J Med 2009;67:134-41.

486. Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, Grosshennig A, Schillert A, Teumer Am Schmidt R, Kathiresan S, Lumley T, Aulchenko YS, König IR, Zeller T, Homuth G, Struchalin M, Aragam J, Bis JC, Rivadeneira F, Erdmann J, Schnabel RB, Dörr M, Zweiker R, Lind L, Rodeheffer RJ, Greiser KH, Levy D, Haritunians T, Deckers JW, Stritzke J, Lackner KJ, Völker U, Ingelsson E, Kullo I, Hearting J, O’Donnell CJ, Heckbert SR, Stricker BH, Ziegler A, Reffelmann T, Redfield MM, Werdan K, Mitchell GF, Rice K, Arnett DK, Hofman A, Gottdiener JS, Uitterlinden AG, Meitinger T, Blettner M, Friedrich N, Wang TJ, Psaty BM, Duijn CM van, Wichmann HE, Munzel TF, Kroemer HK, Benjamin EJ, Rotter JI, Witteman JC, Schunkert H, Schmidt H, Völzke H, Blankenberg S. Genetic variants associated with cardiac structure

and function: a meta-analysis and replication of genome-wide association data. JAMA 2009;8;302:168-78.

487. Vink JM, smit AB, de Geus EJ, Sullivan P, Willemsen G, Hottenga JJ, Smit JH, Hoogendijk WJ, Zitman FG, Peltonen L, Kaprio J, Pedersen NL, Magnusson PK. Spector TD, Kyvik KO, Morley KI, Heath AC, Martin NG, Westendorp RG, Slagboom PE, Tiemeier H, Hofman A, Uitterlinden AG, Aulchenko YS, Amin N, Duijn CM van Penninx BW, Boomsma DI. Genome-wide association study of smoking initiation and current smoking. AM J Hum Genet 2009;84:367-79.

488. Wieren van -Wijer DB de, Maitland-Zee AH van der, de Boer A, Kroon AA, Leeuw PW de, Schiffers P, Janssen RG, Psaty BM, Duijn CM van, Stricker BH, Klungel OH. Interaction between the Gly460Trp alpha-adducin gene variant and diuretics on the risk of myocardial infarction. J Hypertens 2009;27:61-8.

489. Wieren van-Wijer BMA de, Maitland-Zee AH van der, Boer A de, Stricker BHCh, Lievers KJA, Kroon AA, Leeuw PW de, Schiffers P, Janssen RJ, Psaty BM, Bozkurt O, Duijn CM van, Verschuren WMM, Klungel OH. Recruitment of participants through community pharmacies for a pharmacogenetic study of antihypertensive drug treatment. Pharmacy World & Science 2009;31:158-64.

490. Wieren van-Wijer DB de, Maitland-Zee AH van der, Boer A de, Kroon AA, Leeuw PW de, Schiffers P, Janssen RG, Psaty BM, Duijn CM van, Stricker BH, Klungel OH. Reasons for non-response in observational pharmacogenetic research. Pharmacoepidemiol Drug Saf 2009;18:665-71.

491. Willer CJ, Speliotes EK, Loos RJF, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lettre G, Lyon HN, McCarroll SA, Qi L, Roccasecca RM, Sanna S, Scheet PA, Tanaka T, Weedon MN, Wheeler, E, Zhao JH, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chinese P, Coin L, Collins FS, Connell JM, Cooper C, Davey Smith G, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada JK, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Jacobs L, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkannen M, Kuusisto J, Laitinen J, Lakatta EG, Lamina C, Lim N, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O’Rahilly S, Papadakis K, Prokopenko, I, Purmann C, Randall JC, Rees M, Ridderstrale M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Soranzo N, Stephens J, Stevens S, Stringham HM, Timpson NJ, Tung YCL, Valle TT, Duijn CM van, Vimaleswaran KS, Volenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N, Witteman JCM, Zeggini E, Zhai GGuangju, Zillikens MC, Althuler D, Caufield D, Chanock SJ, Farooqi S, Ferruci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin M, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Molhke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann E, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009;41:25-34.

492. Zillikens MC, van Meurs JB, Sijbrands EJ, Rivadeneira F, Dehghan A, van Leeuwen JP, Hofman A, Duijn CM van, Witteman JC, Uitterlinden AG, Pols HA. SIRT1 genetic variation

and mortality in type 2 diabetes: interaction with smoking and dietary niacin. Free Radic Biol Med 2009;15;19:45-51.

493. Zillikens MC, Meurs JB van, Sijbrands EJ, Rivadeneira F, Dehghan A, van Leeuwen JP, Hofman A, Duijn CM van, Witteman JC, Uitterlinden AG, Pols HA. SIRT1 genetic variation and mortality in type 2 diabetes: interaction with smoking and dietary niacin. Free Radic Biol Med 2009;15;46:836-41.

494. Amin N, Duijn CM van, Janssens AC. Genetic Scoring Analysis: a way forward in Genome Wide Association Studies? Eur J Epidemiol 2009;24:585-7

2010

495. Anttila V, Stefansson H, Kallela M, Todt U, Terwindt GM, Calafato MS, Nyholt DR, Dimas AS, Freilinger T, Muller-Myhsok B, Artto V, Inouye M, Alakurtti K, Kaunisto MA, Hamalainen E, de Vries B, Stam AH, Weller CM, Heinze A, Heinze-Kuhn K, Goebel I, Borck G, Gobel H, Steinberg S, Wolf C, Bjornsson A, Gudmundsson G, Kirchmann M, Hauge A, Werge T, Schoenen J, Eriksson JG, Hagen K, Stovner L, Wichmann HE, Meitinger T, Alexander M, Moebus S, Schreiber S, Aulchenko YS, Breteler MM, Uitterlinden AG, Hofman A, van Duijn CM, Tikka-Kleemola P, Vepsalainen S, Lucae S, Tozzi F, Muglia P, Barrett J, Kaprio J, Farkkila M, Peltonen L, Stefansson K, Zwart JA, Ferrari MD, Olesen J, Daly M, Wessman M, van den Maagdenberg AM, Dichgans M, Kubisch C, Dermitzakis ET, Frants RR, Palotie A, International Headache Genetics C. Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Nat Genet 2010; 42:869-873

496. Aulchenko YS, Struchalin MV, van Duijn CM. ProbABEL package for genome-wide association analysis of imputed data. BMC Bioinformatics. 2010; 11:134

497. Baas DC, Despriet DD, Gorgels TG, Bergeron-Sawitzke J, Uitterlinden AG, Hofman A, van Duijn CM, Merriam JE, Smith RT, Barile GR, ten Brink JB, Vingerling JR, Klaver CC, Allikmets R, Dean M, Bergen AA. The ERCC6 gene and age-related macular degeneration. PLoS One 2010; 5:e13786

498. Baas DC, Ho L, Ennis S, Merriam JE, Tanck MW, Uitterlinden AG, de Jong PT, Cree AJ, Griffiths HL, Rivadeneira F, Hofman A, van Duijn C, Smith RT, Barile GR, Gorgels TG, Vingerling JR, Klaver CC, Lotery AJ, Allikmets R, Bergen AA. The complement component 5 gene and age-related macular degeneration. Ophthalmology 2010; 117:500-511

499. Brugts JJ, Isaacs A, Boersma E, van Duijn CM, Uitterlinden AG, Remme W, Bertrand M, Ninomiya T, Ceconi C, Chalmers J, MacMahon S, Fox K, Ferrari R, Witteman JC, Danser AH, Simoons ML, de Maat MP. Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease. Eur Heart J 2010; 31:1854-1864

500. Brugts MP, van Duijn CM, Hofland LJ, Witteman JC, Lamberts SW, Janssen JA. Igf-I bioactivity in an elderly population: relation to insulin sensitivity, insulin levels, and the metabolic syndrome. Diabetes 2010; 59:505-508

501. Collins SJ, Schuur M, Boyd A, Lewis V, Klug GM, McGlade A, van Oosterhout A, Breedveld G, Oostra BA, Masters C, Van Duijn CM. No evidence for prion protein gene locus multiplication in Creutzfeldt-Jakob disease. Neurosci Lett 2010; 472:16-18

502. Combarros O, Warden DR, Hammond N, Cortina-Borja M, Belbin O, Lehmann MG, Wilcock GK, Brown K, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Gwilliam R, Heun R, Kolsch H, Mateo I, Oulhaj A, Arias-Vasquez A, Schuur M, Aulchenko YS, Ikram MA, Breteler MM, van Duijn CM, Morgan K, Smith AD, Lehmann DJ. The dopamine beta-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project. BMC Med Genet. 2010; 11:162

503. Coppus AM, Fekkes D, Verhoeven WM, Tuinier S, van Duijn CM. Plasma levels of nitric oxide related amino acids in demented subjects with Down syndrome are related to neopterin concentrations. Amino Acids 2010; 38:923-928

504. Coppus AM, Evenhuis HM, Verberne GJ, Visser FE, Eikelenboom P, van Gool WA, Janssens AC, van Duijn CM. Early age at menopause is associated with increased risk of dementia and mortality in women with Down syndrome. J Alzheimers Dis 2010; 19:545-550

505. de Moor MH, Costa PT, Terracciano A, Krueger RF, de Geus EJ, Toshiko T, Penninx BW, Esko T, Madden PA, Derringer J, Amin N, Willemsen G, Hottenga JJ, Distel MA, Uda M, Sanna S, Spinhoven P, Hartman CA, Sullivan P, Realo A, Allik J, Heath AC, Pergadia ML, Agrawal A, Lin P, Grucza R, Nutile T, Ciullo M, Rujescu D, Giegling I, Konte B, Widen E, Cousminer DL, Eriksson JG, Palotie A, Peltonen L, Luciano M, Tenesa A, Davies G, Lopez LM, Hansell NK, Medland SE, Ferrucci L, Schlessinger D, Montgomery GW, Wright MJ, Aulchenko YS, Janssens AC, Oostra BA, Metspalu A, Abecasis GR, Deary IJ, Raikkonen K, Bierut LJ, Martin NG, van Duijn CM, Boomsma DI. Meta-analysis of genome-wide association studies for personality. Mol Psychiatry 2010;

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516. Hek K, Mulder CL, Luijendijk HJ, van Duijn CM, Hofman A, Uitterlinden AG, Tiemeier H. The PCLO gene and depressive disorders: replication in a population-based study. Hum Mol Genet 2010; 19:731-734

517. Henneman P, Janssens AC, Zillikens MC, Frolich M, Frants RR, Oostra BA, van Duijn CM, van Dijk KW. Menopause impacts the relation of plasma adiponectin levels with the metabolic syndrome J Intern Med 2010; 267:402-409

518. Henneman P, Aulchenko YS, Frants RR, Zorkoltseva IV, Zillikens MC, Frolich M, Oostra BA, van Dijk KW, van Duijn CM. Genetic architecture of plasma adiponectin overlaps with the genetics of metabolic syndrome-related traits. Diabetes Care 2010; 33:908-913

519. Hysi PG, Young TL, Mackey DA, Andrew T, Fernandez-Medarde A, Solouki AM, Hewitt AW, Macgregor S, Vingerling JR, Li YJ, Ikram MK, Fai LY, Sham PC, Manyes L, Porteros A, Lopes MC, Carbonaro F, Fahy SJ, Martin NG, van Duijn CM, Spector TD, Rahi JS, Santos E, Klaver CC, Hammond CJ. A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25. Nat Genet 2010; 42:902-905

520. Igl W, Johansson A, Wilson JF, Wild SH, Polasek O, Hayward C, Vitart V, Hastie N, Rudan P, Gnewuch C, Schmitz G, Meitinger T, Pramstaller PP, Hicks AA, Oostra BA, van Duijn CM, Rudan I, Wright A, Campbell H, Gyllensten U, Consortium E. Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels. PLoS Genet 2010; 6:e1000798

521. Ikram MK, Xueling S, Jensen RA, Cotch MF, Hewitt AW, Ikram MA, Wang JJ, Klein R, Klein BE, Breteler MM, Cheung N, Liew G, Mitchell P, Uitterlinden AG, Rivadeneira F, Hofman A, de Jong PT, van Duijn CM, Kao L, Cheng CY, Smith AV, Glazer NL, Lumley T, McKnight B, Psaty BM, Jonasson F, Eiriksdottir G, Aspelund T, Global BC, Harris TB, Launer LJ, Taylor KD, Li X, Iyengar SK, Xi Q, Sivakumaran TA, Mackey DA, Macgregor S, Martin NG, Young TL, Bis JC, Wiggins KL, Heckbert SR, Hammond CJ, Andrew T, Fahy S, Attia J, Holliday EG, Scott RJ, Islam FM, Rotter JI, McAuley AK, Boerwinkle E, Tai ES, Gudnason V, Siscovick DS, Vingerling JR, Wong TY. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet 2010; 6:e1001184

522. Jaddoe VW, van Duijn CM, van der Heijden AJ, Mackenbach JP, Moll HA, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, Hofman A. The Generation R Study: design and cohort update 2010. Eur J Epidemiol 2010; 25:823-841

523. Jafari N, Broer L, Hoppenbrouwers IA, van Duijn CM, Hintzen RQ. Infectious mononucleosis-linked HLA class I single nucleotide polymorphism is associated with multiple sclerosis. Mult Scler 2010; 16:1303-1307

524. Janssens AC, van Duijn CM. An epidemiological perspective on the future of direct-to-consumer personal genome testing. Investig Genet 2010; 1:10

525. Johansson A, Marroni F, Hayward C, Franklin CS, Kirichenko AV, Jonasson I, Hicks AA, Vitart V, Isaacs A, Axenovich T, Campbell S, Floyd J, Hastie N, Knott S, Lauc G, Pichler I, Rotim K, Wild SH, Zorkoltseva IV, Wilson JF, Rudan I, Campbell H, Pattaro C, Pramstaller P, Oostra BA, Wright AF, van Duijn CM, Aulchenko YS, Gyllensten U, Consortium E. Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene. Obesity (Silver Spring) 2010; 18:803-808

526. Kestenbaum B, Glazer NL, Kottgen A, Felix JF, Hwang SJ, Liu Y, Lohman K, Kritchevsky SB, Hausman DB, Petersen AK, Gieger C, Ried JS, Meitinger T, Strom TM, Wichmann HE, Campbell H, Hayward C, Rudan I, de Boer IH, Psaty BM, Rice KM, Chen YD, Li M, Arking DE, Boerwinkle E, Coresh J, Yang Q, Levy D, van Rooij FJ, Dehghan A, Rivadeneira F, Uitterlinden AG, Hofman A, van Duijn CM, Shlipak MG, Kao WH, Witteman JC, Siscovick DS, Fox CS. Common genetic variants associate with serum phosphorus concentration. J Am Soc Nephrol 2010; 21:1223-1232

527. Kettunen J, Silander K, Saarela O, Amin N, Muller M, Timpson N, Surakka I, Ripatti S, Laitinen J, Hartikainen AL, Pouta A, Lahermo P, Anttila V, Mannisto S, Jula A, Virtamo J, Salomaa V, Lehtimaki T, Raitakari O, Gieger C, Wichmann EH, van Duijn CM, Smith GD, McCarthy MI, Jarvelin MR, Perola M, Peltonen L. European lactase persistence genotype shows evidence of association with increase in body mass index. Hum Mol Genet 2010; 19:1129-1136

528. Kottgen A, Pattaro C, Boger CA, Fuchsberger C, Olden M, Glazer NL, Parsa A, Gao X, Yang Q, Smith AV, O'Connell JR, Li M, Schmidt H, Tanaka T, Isaacs A, Ketkar S, Hwang SJ, Johnson AD, Dehghan A, Teumer A, Pare G, Atkinson EJ, Zeller T, Lohman K, Cornelis MC, Probst-Hensch NM, Kronenberg F, Tonjes A, Hayward C, Aspelund T, Eiriksdottir G, Launer LJ, Harris TB, Rampersaud E, Mitchell BD, Arking DE, Boerwinkle E, Struchalin M, Cavalieri M, Singleton A, Giallauria F, Metter J, de Boer IH, Haritunians T, Lumley T, Siscovick D, Psaty BM, Zillikens MC, Oostra BA, Feitosa M, Province M, de Andrade M, Turner ST, Schillert A, Ziegler A, Wild PS, Schnabel RB, Wilde S, Munzel TF, Leak TS, Illig T, Klopp N, Meisinger C, Wichmann HE, Koenig W, Zgaga L, Zemunik T, Kolcic I, Minelli C, Hu FB, Johansson A, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Schreiber S, Aulchenko YS, Felix JF, Rivadeneira F, Uitterlinden AG, Hofman A, Imboden M, Nitsch D, Brandstatter A, Kollerits B, Kedenko L, Magi R, Stumvoll M, Kovacs P, Boban M, Campbell S, Endlich K, Volzke H, Kroemer HK, Nauck M, Volker U, Polasek O, Vitart V, Badola S, Parker AN, Ridker PM, Kardia SL, Blankenberg S, Liu Y, Curhan GC, Franke A, Rochat T, Paulweber B, Prokopenko I, Wang W, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Shlipak MG, van Duijn CM, Borecki I, Kramer BK, Rudan I, Gyllensten U, Wilson JF, Witteman JC, Pramstaller PP, Rettig R, Hastie N, Chasman DI, Kao WH, Heid IM, Fox CS. New loci associated with kidney function and chronic kidney disease. Nat Genet 2010; 42:376-384

529. Kovacs GG, Sanchez-Juan P, Strobel T, Schuur M, Poleggi A, Nocentini S, Giannattasio C, Belay G, Bishop M, Capellari S, Parchi P, Gelpi E, Gal A, Bakos A, Molnar MJ, Heinemann U, Zerr I, Knight RS, Mitrova E, van Duijn C, Budka H. Cathepsin D (C224T) polymorphism in sporadic and genetic Creutzfeldt-Jakob disease. Alzheimer Dis Assoc Disord 2010; 24:104-107

530. Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segre AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Magi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Carola Zillikens M, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Hua Zhao J, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, Konig IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Muller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpelainen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Pare G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietilainen KH, Pouta A, Ridderstrale M, Rotter JI, Sambrook JG, Sanders AR, Oliver Schmidt C, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, Kahonen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtimaki T, Melander O, Mosley TH, Jr., Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, Tonjes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Gronberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Mark Lathrop G, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Adrienne Cupples L, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, Volzke H, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden AG, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn JN. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010; 467:832-838

531. Lehmann DJ, Schuur M, Warden DR, Hammond N, Belbin O, Kolsch H, Lehmann MG, Wilcock GK, Brown K, Kehoe PG, Morris CM, Barker R, Coto E, Alvarez V, Deloukas P, Mateo I, Gwilliam R, Combarros O, Arias-Vasquez A, Aulchenko YS, Ikram MA, Breteler MM, van Duijn CM, Oulhaj A, Heun R, Cortina-Borja M, Morgan K, Robson K, Smith AD. Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project. Neurobiol Aging 2010;

532. Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, Aulchenko Y, Lumley T, Köttgen A, Vasan RS, Rivadeneira F, Eiriksdottir G, Guo X, Arking DE, Mitchell GF, Mattace-Raso FU, Smith AV, Taylor K, Scharpf RB, Hwang SJ, Sijbrands EJ, Bis J, Harris TB, Ganesh SK, O'Donnell CJ, Hofman A, Rotter JI, Coresh J, Benjamin EJ, Uitterlinden AG, Heiss G, Fox CS, Witteman JC, Boerwinkle E, Wang TJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, van Duijn CM.Genome-wide association study of blood pressure and hypertension.Nat Genet 2009 Jun;41:677-87

533. Liu F, Pardo LM, Schuur M, Sanchez-Juan P, Isaacs A, Sleegers K, de Koning I, Zorkoltseva IV, Axenovich TI, Witteman JC, Janssens AC, van Swieten JC, Aulchenko YS, Oostra BA, van Duijn CM. The apolipoprotein E gene and its age-specific effects on cognitive function. Neurobiol Aging 2010; 31:1831-1833

534. Lopez-Leon S, Aulchenko YS, Tiemeier H, Oostra BA, van Duijn CM, Janssens AC. Shared genetic factors in the co-occurrence of symptoms of depression and cardiovascular risk factors. J Affect Disord 2010; 122:247-252

535. Maas JA, Mook-Kanamori DO, Ay L, Steegers EA, van Duijn CM, Hofman A, Hokken-Koelega AC, Jaddoe VW. Insulin VNTR and IGF-1 promoter region polymorphisms are not associated with body composition in early childhood: the generation R study. Horm Res Paediatr 2010; 73:120-127

536. Maitland-van der Zee AH, van Wieren-de Wijer DB, de Boer A, Kroon AA, de Leeuw PW, Schiffers P, Janssen RG, Psaty BM, van Duijn CM, Stricker BH, Klungel OH. Genetic variation in the renin-angiotensin system, use of renin-angiotensin system inhibitors and the risk of myocardialinfarction. J Renin Angiotensin Aldosterone Syst. 2010;

537. Mascalzoni D, Janssens AC, Stewart A, Pramstaller P, Gyllensten U, Rudan I, van Duijn CM, Wilson JF, Campbell H, Quillan RM, consortium E. Comparison of participant information and informed consent forms of five European studies in genetic isolated populations. Eur J Hum Genet 2010; 18:296-302

538. Meulenbelt I, Bos SD, Kloppenburg M, Lakenberg N, Houwing-Duistermaat JJ, Watt I, de Craen AJ, van Duijn CM, Slagboom PE. Interleukin-1 gene cluster variants with innate cytokine production profiles and osteoarthritis in subjects from the Genetics, Osteoarthritis and Progression Study. Arthritis Rheum 2010; 62:1119-1126

539. Meyer TE, Verwoert GC, Hwang SJ, Glazer NL, Smith AV, van Rooij FJ, Ehret GB, Boerwinkle E, Felix JF, Leak TS, Harris TB, Yang Q, Dehghan A, Aspelund T, Katz R, Homuth G, Kocher T, Rettig R, Ried JS, Gieger C, Prucha H, Pfeufer A, Meitinger T, Coresh J, Hofman A, Sarnak MJ, Chen YD, Uitterlinden AG, Chakravarti A, Psaty BM, van Duijn CM, Kao WH, Witteman JC, Gudnason V, Siscovick DS, Fox CS, Kottgen A, Genetic Factors for Osteoporosis C, Meta Analysis of G, Insulin Related Traits C. Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels. PLoS Genet 2010; 6

540. Mihaescu R, Detmar SB, Cornel MC, van der Flier WM, Heutink P, Hol EM, Rikkert MG, van Duijn CM, Janssens AC. Translational research in genomics of Alzheimer's disease: a review of current practice and future perspectives. J Alzheimers Dis 2010; 20:967-980

541. de Moor MH, Costa PT, Terracciano A, Krueger RF, de Geus EJ, Toshiko T, Penninx BW, Esko T, Madden PA, Derringer J, Amin N, Willemsen G, Hottenga JJ, Distel MA, Uda M, Sanna S, Spinhoven P, Hartman CA, Sullivan P, Realo A, Allik J, Heath AC, Pergadia ML, Agrawal A, Lin P, Grucza R, Nutile T, Ciullo M, Rujescu D, Giegling I, Konte B, Widen E, Cousminer DL, Eriksson JG, Palotie A, Peltonen L, Luciano M, Tenesa A, Davies G, Lopez LM, Hansell NK, Medland SE, Ferrucci L, Schlessinger D, Montgomery GW, Wright MJ, Aulchenko YS, Janssens AC, Oostra BA, Metspalu A, Abecasis GR, Deary IJ, Räikkönen K, Bierut LJ, Martin NG, van Duijn CM, Boomsma DI. Meta-analysis of genome-wide association studies for personality.

542. Mihaescu R, van Zitteren M, van Hoek M, Sijbrands EJ, Uitterlinden AG, Witteman JC, Hofman A, Hunink MG, van Duijn CM, Janssens AC. Improvement of risk prediction by genomic profiling: reclassification measures versus the area under the receiver operating characteristic curve. Am J Epidemiol 2010; 172:353-361

543. Mook-Kanamori DO, Ay L, Hofman A, van Duijn CM, Moll HA, Raat H, Hokken-Koelega AC, Jaddoe VW. No association of obesity gene FTO with body composition at the age of 6 months. The Generation R Study. J Endocrinol Invest. 2011; 34:16-20

544. Morrison AC, Felix JF, Cupples LA, Glazer NL, Loehr LR, Dehghan A, Demissie S, Bis JC, Rosamond WD, Aulchenko YS, Wang YA, Haritunians T, Folsom AR, Rivadeneira F, Benjamin EJ, Lumley T, Couper D, Stricker BH, O'Donnell CJ, Rice KM, Chang PP, Hofman A, Levy D, Rotter JI, Fox ER, Uitterlinden AG, Wang TJ, Psaty BM, Willerson JT, van Duijn CM, Boerwinkle E, Witteman JC, Vasan RS, Smith NL. Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. Circ Cardiovasc Genet 2010; 3:248-255

545. Naukkarinen J, Surakka I, Pietilainen KH, Rissanen A, Salomaa V, Ripatti S, Yki-Jarvinen H, van Duijn CM, Wichmann HE, Kaprio J, Taskinen MR, Peltonen L, Consortium E. Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes. PLoS Genet 2010; 6:e1000976

546. Nettleton JA, McKeown NM, Kanoni S, Lemaitre RN, Hivert MF, Ngwa J, van Rooij FJ, Sonestedt E, Wojczynski MK, Ye Z, Tanaka T; Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. CHARGE Whole Grain Foods Study Group. Diabetes Care 2010 Dec;33:2684-91.

547. Newman AB, Walter S, Lunetta KL, Garcia ME, Slagboom PE, Christensen K, Arnold AM, Aspelund T, Aulchenko YS, Benjamin EJ, Christiansen L, D'Agostino RB, Sr., Fitzpatrick AL, Franceschini N, Glazer NL, Gudnason V, Hofman A, Kaplan R, Karasik D, Kelly-Hayes M, Kiel DP, Launer LJ, Marciante KD, Massaro JM, Miljkovic I, Nalls MA, Hernandez D, Psaty BM, Rivadeneira F, Rotter J, Seshadri S, Smith AV, Taylor KD, Tiemeier H, Uh HW, Uitterlinden AG, Vaupel JW, Walston J, Westendorp RG, Harris TB, Lumley T, van Duijn CM, Murabito JM. A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. J Gerontol A Biol Sci Med Sci 2010; 65:478-487

548. O'Dushlaine C, McQuillan R, Weale ME, Crouch DJ, Johansson A, Aulchenko Y, Franklin CS, Polasek O, Fuchsberger C, Corvin A, Hicks AA, Vitart V, Hayward C, Wild SH, Meitinger T, van Duijn CM, Gyllensten U, Wright AF, Campbell H, Pramstaller PP, Rudan I, Wilson JF. Genes predict village of origin in rural Europe. Eur J Hum Genet 2010; 18:1269-1270

549. Pardo Silva MC, Njajou OT, Alizadeh BZ, Hofman A, Witteman JC, van Duijn CM, Janssens AC. HFE gene mutations increase the risk of coronary heart disease in women. Eur J Epidemiol 2010; 25:643-649

550. Pattaro C, De Grandi A, Vitart V, Hayward C, Franke A, Aulchenko YS, Johansson A, Wild SH, Melville SA, Isaacs A, Polasek O, Ellinghaus D, Kolcic I, Nothlings U, Zgaga L, Zemunik T, Gnewuch C, Schreiber S, Campbell S, Hastie N, Boban M, Meitinger T, Oostra BA, Riegler P, Minelli C, Wright AF, Campbell H, van Duijn CM, Gyllensten U, Wilson JF, Krawczak M, Rudan I, Pramstaller PP, consortium E. A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level. BMC Med Genet 2010; 11:41

551. Pecioska S, Zillikens MC, Henneman P, Snijders PJ, Oostra BA, van Duijn CM, Aulchenko YS. Association between type 2 diabetes loci and measures of fatness. PLoS One 2010; 5:e8541

552. Peters BJ, Rodin AS, Klungel OH, van Duijn CM, Stricker BH, van't Slot R, de Boer A, Maitland-van der Zee AH. Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction. Pharmacogenomics 2010; 11:1065-1076

553. Pfeufer A, van Noord C, Marciante KD, Arking DE, Larson MG, Smith AV, Tarasov KV, Muller M, Sotoodehnia N, Sinner MF, Verwoert GC, Li M, Kao WH, Kottgen A, Coresh J, Bis JC, Psaty BM, Rice K, Rotter JI, Rivadeneira F, Hofman A, Kors JA, Stricker BH, Uitterlinden AG, van Duijn CM, Beckmann BM, Sauter W, Gieger C, Lubitz SA, Newton-Cheh C, Wang TJ, Magnani JW, Schnabel RB, Chung MK, Barnard J, Smith JD, Van Wagoner DR, Vasan RS, Aspelund T, Eiriksdottir G, Harris TB, Launer LJ, Najjar SS, Lakatta E, Schlessinger D, Uda M, Abecasis GR, Muller-Myhsok B, Ehret GB, Boerwinkle E, Chakravarti A, Soliman EZ, Lunetta KL, Perz S, Wichmann HE, Meitinger T, Levy D, Gudnason V, Ellinor PT, Sanna S, Kaab S, Witteman JC, Alonso A, Benjamin EJ, Heckbert SR. Genome-wide association study of PR interval. Nat Genet 2010; 42:153-159

554. Ramdas WD, Amin N, van Koolwijk LM, Janssens AC, Demirkan A, de Jong PT, Aulchenko YS, Wolfs RC, Hofman A, Rivadeneira F, Uitterlinden AG, Oostra BA, Lemij HG, Klaver CC, Vingerling JR, Jansonius NM, van Duijn CM. Genetic architecture of open angle glaucoma and related determinants. J Med Genet. 2011; 48:190-196

555. Ramdas WD, van Koolwijk LM, Ikram MK, Jansonius NM, de Jong PT, Bergen AA, Isaacs A, Amin N, Aulchenko YS, Wolfs RC, Hofman A, Rivadeneira F, Oostra BA, Uitterlinden AG, Hysi P, Hammond CJ, Lemij HG, Vingerling JR, Klaver CC, van Duijn CM. A genome-wide association study of optic disc parameters. PLoS Genet. 2010; 6:e1000978

556. Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J,

Stringham HM, Prokopenko I, Johnson T, Grarup N, Boesgaard TW, Lecoeur C, Shrader P, O'Connell J, Ingelsson E, Couper DJ, Rice K, Song K, Andreasen CH, Dina C, Kottgen A, Le Bacquer O, Pattou F, Taneera J, Steinthorsdottir V, Rybin D, Ardlie K, Sampson M, Qi L, van Hoek M, Weedon MN, Aulchenko YS, Voight BF, Grallert H, Balkau B, Bergman RN, Bielinski SJ, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Bottcher Y, Brunner E, Buchanan TA, Bumpstead SJ, Cavalcanti-Proenca C, Charpentier G, Chen YD, Chines PS, Collins FS, Cornelis M, G JC, Delplanque J, Doney A, Egan JM, Erdos MR, Firmann M, Forouhi NG, Fox CS, Goodarzi MO, Graessler J, Hingorani A, Isomaa B, Jorgensen T, Kivimaki M, Kovacs P, Krohn K, Kumari M, Lauritzen T, Levy-Marchal C, Mayor V, McAteer JB, Meyre D, Mitchell BD, Mohlke KL, Morken MA, Narisu N, Palmer CN, Pakyz R, Pascoe L, Payne F, Pearson D, Rathmann W, Sandbaek A, Sayer AA, Scott LJ, Sharp SJ, Sijbrands E, Singleton A, Siscovick DS, Smith NL, Sparso T, Swift AJ, Syddall H, Thorleifsson G, Tonjes A, Tuomi T, Tuomilehto J, Valle TT, Waeber G, Walley A, Waterworth DM, Zeggini E, Zhao JH, consortium G, investigators M, Illig T, Wichmann HE, Wilson JF, van Duijn C, Hu FB, Morris AD, Frayling TM, Hattersley AT, Thorsteinsdottir U, Stefansson K, Nilsson P, Syvanen AC, Shuldiner AR, Walker M, Bornstein SR, Schwarz P, Williams GH, Nathan DM, Kuusisto J, Laakso M, Cooper C, Marmot M, Ferrucci L, Mooser V, Stumvoll M, Loos RJ, Altshuler D, Psaty BM, Rotter JI, Boerwinkle E, Hansen T, Pedersen O, Florez JC, McCarthy MI, Boehnke M, Barroso I, Sladek R, Froguel P, Meigs JB, Groop L, Wareham NJ, Watanabe RM. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet. 2010; 42:142-148

557. Schol-Gelok S, Janssens AC, Tiemeier H, Liu F, Lopez-Leon S, Zorkoltseva IV, Axenovich TI, van Swieten JC, Uitterlinden AG, Hofman A, Aulchenko YS, Oostra BA, van Duijn CM. A genome-wide screen for depression in two independent Dutch populations. Biol Psychiatry 2010; 68:187-196

558. Schuur M, Henneman P, van Swieten JC, Zillikens MC, de Koning I, Janssens AC, Witteman JC, Aulchenko YS, Frants RR, Oostra BA, van Dijk KW, van Duijn CM. Insulin-resistance and metabolic syndrome are related to executive function in women in a large family-based study. Eur J Epidemiol 2010; 25:561-568

559. Schuur M, van Swieten JC, Schol-Gelok S, Ikram MA, Vernooij MW, Liu F, Isaacs A, de Boer R, de Koning I, Niessen WJ, Vrooman H, Oostra BA, van der Lugt A, Breteler MM, van Duijn CM. Genetic risk factors for cerebral small-vessel disease in hypertensive patients from a genetically isolated population. J Neurol Neurosurg Psychiatry 2011; 82:41-44

560. Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT, Jr., Janssens AC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund T, Hernandez I, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Antunez C, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Lopez-Arrieta J, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Ruiz A, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez OL, van Duijn CM, Breteler MM, Consortium C, Consortium G, Consortium E. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010; 303:1832-1840

561. Smedts HP, Isaacs A, de Costa D, Uitterlinden AG, van Duijn CM, Gittenberger-de Groot AC, Helbing WA, Steegers EA, Steegers-Theunissen RP. VEGF polymorphisms are

associated with endocardial cushion defects: a family-based case-control study. Pediatr Res 2010; 67:23-28

562. Smith NL, Felix JF, Morrison AC, Demissie S, Glazer NL, Loehr LR, Cupples LA, Dehghan A, Lumley T, Rosamond WD, Lieb W, Rivadeneira F, Bis JC, Folsom AR, Benjamin E, Aulchenko YS, Haritunians T, Couper D, Murabito J, Wang YA, Stricker BH, Gottdiener JS, Chang PP, Wang TJ, Rice KM, Hofman A, Heckbert SR, Fox ER, O'Donnell CJ, Uitterlinden AG, Rotter JI, Willerson JT, Levy D, van Duijn CM, Psaty BM, Witteman JC, Boerwinkle E, Vasan RS. Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet 2010; 3:256-266

563. Smith NL, Chen MH, Dehghan A, Strachan DP, Basu S, Soranzo N, Hayward C, Rudan I, Sabater-Lleal M, Bis JC, de Maat MP, Rumley A, Kong X, Yang Q, Williams FM, Vitart V, Campbell H, Malarstig A, Wiggins KL, van Duijn CM, McArdle WL, Pankow JS, Johnson AD, Silveira A, McKnight B, Uitterlinden AG, Wellcome Trust Case Control C, Aleksic N, Meigs JB, Peters A, Koenig W, Cushman M, Kathiresan S, Rotter JI, Bovill EG, Hofman A, Boerwinkle E, Tofler GH, Peden JF, Psaty BM, Leebeek F, Folsom AR, Larson MG, Spector TD, Wright AF, Wilson JF, Hamsten A, Lumley T, Witteman JC, Tang W, O'Donnell CJ. Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation 2010; 121:1382-1392

564. Sofat R, Hingorani AD, Smeeth L, Humphries SE, Talmud PJ, Cooper J, Shah T, Sandhu MS, Ricketts SL, Boekholdt SM, Wareham N, Khaw KT, Kumari M, Kivimaki M, Marmot M, Asselbergs FW, van der Harst P, Dullaart RP, Navis G, van Veldhuisen DJ, Van Gilst WH, Thompson JF, McCaskie P, Palmer LJ, Arca M, Quagliarini F, Gaudio C, Cambien F, Nicaud V, Poirer O, Gudnason V, Isaacs A, Witteman JC, van Duijn CM, Pencina M, Vasan RS, D'Agostino RB, Sr., Ordovas J, Li TY, Kakko S, Kauma H, Savolainen MJ, Kesaniemi YA, Sandhofer A, Paulweber B, Sorli JV, Goto A, Yokoyama S, Okumura K, Horne BD, Packard C, Freeman D, Ford I, Sattar N, McCormack V, Lawlor DA, Ebrahim S, Smith GD, Kastelein JJ, Deanfield J, Casas JP. Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms. Circulation 2010; 121:52-62

565. Solouki AM, Verhoeven VJ, van Duijn CM, Verkerk AJ, Ikram MK, Hysi PG, Despriet DD, van Koolwijk LM, Ho L, Ramdas WD, Czudowska M, Kuijpers RW, Amin N, Struchalin M, Aulchenko YS, van Rij G, Riemslag FC, Young TL, Mackey DA, Spector TD, Gorgels TG, Willemse-Assink JJ, Isaacs A, Kramer R, Swagemakers SM, Bergen AA, van Oosterhout AA, Oostra BA, Rivadeneira F, Uitterlinden AG, Hofman A, de Jong PT, Hammond CJ, Vingerling JR, Klaver CC. A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. Nat Genet 2010; 42:897-901

566. Sotoodehnia N, Isaacs A, de Bakker PI, Dorr M, Newton-Cheh C, Nolte IM, van der Harst P, Muller M, Eijgelsheim M, Alonso A, Hicks AA, Padmanabhan S, Hayward C, Smith AV, Polasek O, Giovannone S, Fu J, Magnani JW, Marciante KD, Pfeufer A, Gharib SA, Teumer A, Li M, Bis JC, Rivadeneira F, Aspelund T, Kottgen A, Johnson T, Rice K, Sie MP, Wang YA, Klopp N, Fuchsberger C, Wild SH, Mateo Leach I, Estrada K, Volker U, Wright AF, Asselbergs FW, Qu J, Chakravarti A, Sinner MF, Kors JA, Petersmann A, Harris TB, Soliman EZ, Munroe PB, Psaty BM, Oostra BA, Cupples LA, Perz S, de Boer RA,

Uitterlinden AG, Volzke H, Spector TD, Liu FY, Boerwinkle E, Dominiczak AF, Rotter JI, van Herpen G, Levy D, Wichmann HE, van Gilst WH, Witteman JC, Kroemer HK, Kao WH, Heckbert SR, Meitinger T, Hofman A, Campbell H, Folsom AR, van Veldhuisen DJ, Schwienbacher C, O'Donnell CJ, Volpato CB, Caulfield MJ, Connell JM, Launer L, Lu X, Franke L, Fehrmann RS, te Meerman G, Groen HJ, Weersma RK, van den Berg LH, Wijmenga C, Ophoff RA, Navis G, Rudan I, Snieder H, Wilson JF, Pramstaller PP, Siscovick DS, Wang TJ, Gudnason V, van Duijn CM, Felix SB, Fishman GI, Jamshidi Y, Stricker BH, Samani NJ, Kaab S, Arking DE. Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet 2010; 42:1068-1076

567. Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Allen HL, Lindgren CM, Luan J, Magi R, Randall JC, Vedantam S, Winkler TW, Qi L, Workalemahu T, Heid IM, Steinthorsdottir V, Stringham HM, Weedon MN, Wheeler E, Wood AR, Ferreira T, Weyant RJ, Segre AV, Estrada K, Liang L, Nemesh J, Park JH, Gustafsson S, Kilpelainen TO, Yang J, Bouatia-Naji N, Esko T, Feitosa MF, Kutalik Z, Mangino M, Raychaudhuri S, Scherag A, Smith AV, Welch R, Zhao JH, Aben KK, Absher DM, Amin N, Dixon AL, Fisher E, Glazer NL, Goddard ME, Heard-Costa NL, Hoesel V, Hottenga JJ, Johansson A, Johnson T, Ketkar S, Lamina C, Li S, Moffatt MF, Myers RH, Narisu N, Perry JR, Peters MJ, Preuss M, Ripatti S, Rivadeneira F, Sandholt C, Scott LJ, Timpson NJ, Tyrer JP, van Wingerden S, Watanabe RM, White CC, Wiklund F, Barlassina C, Chasman DI, Cooper MN, Jansson JO, Lawrence RW, Pellikka N, Prokopenko I, Shi J, Thiering E, Alavere H, Alibrandi MT, Almgren P, Arnold AM, Aspelund T, Atwood LD, Balkau B, Balmforth AJ, Bennett AJ, Ben-Shlomo Y, Bergman RN, Bergmann S, Biebermann H, Blakemore AI, Boes T, Bonnycastle LL, Bornstein SR, Brown MJ, Buchanan TA, Busonero F, Campbell H, Cappuccio FP, Cavalcanti-Proenca C, Chen YD, Chen CM, Chines PS, Clarke R, Coin L, Connell J, Day IN, Heijer M, Duan J, Ebrahim S, Elliott P, Elosua R, Eiriksdottir G, Erdos MR, Eriksson JG, Facheris MF, Felix SB, Fischer-Posovszky P, Folsom AR, Friedrich N, Freimer NB, Fu M, Gaget S, Gejman PV, Geus EJ, Gieger C, Gjesing AP, Goel A, Goyette P, Grallert H, Grassler J, Greenawalt DM, Groves CJ, Gudnason V, Guiducci C, Hartikainen AL, Hassanali N, Hall AS, Havulinna AS, Hayward C, Heath AC, Hengstenberg C, Hicks AA, Hinney A, Hofman A, Homuth G, Hui J, Igl W, Iribarren C, Isomaa B, Jacobs KB, Jarick I, Jewell E, John U, Jorgensen T, Jousilahti P, Jula A, Kaakinen M, Kajantie E, Kaplan LM, Kathiresan S, Kettunen J, Kinnunen L, Knowles JW, Kolcic I, Konig IR, Koskinen S, Kovacs P, Kuusisto J, Kraft P, Kvaloy K, Laitinen J, Lantieri O, Lanzani C, Launer LJ, Lecoeur C, Lehtimaki T, Lettre G, Liu J, Lokki ML, Lorentzon M, Luben RN, Ludwig B, Magic, Manunta P, Marek D, Marre M, Martin NG, McArdle WL, McCarthy A, McKnight B, Meitinger T, Melander O, Meyre D, Midthjell K, Montgomery GW, Morken MA, Morris AP, Mulic R, Ngwa JS, Nelis M, Neville MJ, Nyholt DR, O'Donnell CJ, O'Rahilly S, Ong KK, Oostra B, Pare G, Parker AN, Perola M, Pichler I, Pietilainen KH, Platou CG, Polasek O, Pouta A, Rafelt S, Raitakari O, Rayner NW, Ridderstrale M, Rief W, Ruokonen A, Robertson NR, Rzehak P, Salomaa V, Sanders AR, Sandhu MS, Sanna S, Saramies J, Savolainen MJ, Scherag S, Schipf S, Schreiber S, Schunkert H, Silander K, Sinisalo J, Siscovick DS, Smit JH, Soranzo N, Sovio U, Stephens J, Surakka I, Swift AJ, Tammesoo ML, Tardif JC, Teder-Laving M, Teslovich TM, Thompson JR, Thomson B, Tonjes A, Tuomi T, van Meurs JB, van Ommen GJ, Vatin V, Viikari J, Visvikis-Siest S, Vitart V, Vogel CI, Voight BF, Waite LL, Wallaschofski H, Walters GB, Widen E, Wiegand S, Wild SH, Willemsen G, Witte DR, Witteman JC, Xu J, Zhang Q, Zgaga L, Ziegler A, Zitting P, Beilby JP, Farooqi IS, Hebebrand J, Huikuri HV, James AL, Kahonen M, Levinson DF, Macciardi F, Nieminen MS, Ohlsson C, Palmer LJ, Ridker PM, Stumvoll M, Beckmann JS, Boeing H, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Collins FS, Cupples LA, Smith GD, Erdmann J, Froguel P, Gronberg H, Gyllensten U, Hall P, Hansen T, Harris TB,

Hattersley AT, Hayes RB, Heinrich J, Hu FB, Hveem K, Illig T, Jarvelin MR, Kaprio J, Karpe F, Khaw KT, Kiemeney LA, Krude H, Laakso M, Lawlor DA, Metspalu A, Munroe PB, Ouwehand WH, Pedersen O, Penninx BW, Peters A, Pramstaller PP, Quertermous T, Reinehr T, Rissanen A, Rudan I, Samani NJ, Schwarz PE, Shuldiner AR, Spector TD, Tuomilehto J, Uda M, Uitterlinden A, Valle TT, Wabitsch M, Waeber G, Wareham NJ, Watkins H, Procardis C, Wilson JF, Wright AF, Zillikens MC, Chatterjee N, McCarroll SA, Purcell S, Schadt EE, Visscher PM, Assimes TL, Borecki IB, Deloukas P, Fox CS, Groop LC, Haritunians T, Hunter DJ, Kaplan RC, Mohlke KL, O'Connell JR, Peltonen L, Schlessinger D, Strachan DP, van Duijn CM, Wichmann HE, Frayling TM, Thorsteinsdottir U, Abecasis GR, Barroso I, Boehnke M, Stefansson K, North KE, McCarthy MI, Hirschhorn JN, Ingelsson E, Loos RJ. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010; 42:937-948

568. Stam AH, de Vries B, Janssens AC, Vanmolkot KR, Aulchenko YS, Henneman P, Oostra BA, Frants RR, van den Maagdenberg AM, Ferrari MD, van Duijn CM, Terwindt GM. Shared genetic factors in migraine and depression: evidence from a genetic isolate. Neurology. 2010; 74:288-294

569. Struchalin MV, Dehghan A, Witteman JC, van Duijn C, Aulchenko YS. Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations. BMC Genet 2010; 11:92

570. Terracciano A, Sanna S, Uda M, Deiana B, Usala G, Busonero F, Maschio A, Scally M, Patriciu N, Chen WM, Distel MA, Slagboom EP, Boomsma DI, Villafuerte S, Sliwerska E, Burmeister M, Amin N, Janssens AC, van Duijn CM, Schlessinger D, Abecasis GR, Costa PT, Jr. Genome-wide association scan for five major dimensions of personality. Mol Psychiatry 2010; 15:647-656

571. Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Aulchenko YS, Thorleifsson G, Feitosa MF, Chambers J, Orho-Melander M, Melander O, Johnson T, Li X, Guo X, Li M, Shin Cho Y, Jin Go M, Jin Kim Y, Lee JY, Park T, Kim K, Sim X, Twee-Hee Ong R, Croteau-Chonka DC, Lange LA, Smith JD, Song K, Hua Zhao J, Yuan X, Luan J, Lamina C, Ziegler A, Zhang W, Zee RY, Wright AF, Witteman JC, Wilson JF, Willemsen G, Wichmann HE, Whitfield JB, Waterworth DM, Wareham NJ, Waeber G, Vollenweider P, Voight BF, Vitart V, Uitterlinden AG, Uda M, Tuomilehto J, Thompson JR, Tanaka T, Surakka I, Stringham HM, Spector TD, Soranzo N, Smit JH, Sinisalo J, Silander K, Sijbrands EJ, Scuteri A, Scott J, Schlessinger D, Sanna S, Salomaa V, Saharinen J, Sabatti C, Ruokonen A, Rudan I, Rose LM, Roberts R, Rieder M, Psaty BM, Pramstaller PP, Pichler I, Perola M, Penninx BW, Pedersen NL, Pattaro C, Parker AN, Pare G, Oostra BA, O'Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, Meitinger T, McPherson R, McCarthy MI, McArdle W, Masson D, Martin NG, Marroni F, Mangino M, Magnusson PK, Lucas G, Luben R, Loos RJ, Lokki ML, Lettre G, Langenberg C, Launer LJ, Lakatta EG, Laaksonen R, Kyvik KO, Kronenberg F, Konig IR, Khaw KT, Kaprio J, Kaplan LM, Johansson A, Jarvelin MR, Janssens AC, Ingelsson E, Igl W, Kees Hovingh G, Hottenga JJ, Hofman A, Hicks AA, Hengstenberg C, Heid IM, Hayward C, Havulinna AS, Hastie ND, Harris TB, Haritunians T, Hall AS, Gyllensten U, Guiducci C, Groop LC, Gonzalez E, Gieger C, Freimer NB, Ferrucci L, Erdmann J, Elliott P, Ejebe KG, Doring A, Dominiczak AF, Demissie S, Deloukas P, de Geus EJ, de Faire U, Crawford G, Collins FS, Chen YD, Caulfield MJ, Campbell H, Burtt NP, Bonnycastle LL, Boomsma DI, Boekholdt SM, Bergman RN, Barroso I, Bandinelli S, Ballantyne CM,

Assimes TL, Quertermous T, Altshuler D, Seielstad M, Wong TY, Tai ES, Feranil AB, Kuzawa CW, Adair LS, Taylor HA, Jr., Borecki IB, Gabriel SB, Wilson JG, Holm H, Thorsteinsdottir U, Gudnason V, Krauss RM, Mohlke KL, Ordovas JM, Munroe PB, Kooner JS, Tall AR, Hegele RA, Kastelein JJ, Schadt EE, Rotter JI, Boerwinkle E, Strachan DP, Mooser V, Stefansson K, Reilly MP, Samani NJ, Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, van Duijn CM, Peltonen L, Abecasis GR, Boehnke M, Kathiresan S. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010; 466:707-713

572. Thorgeirsson TE, Gudbjartsson DF, Surakka I, Vink JM, Amin N, Geller F, Sulem P, Rafnar T, Esko T, Walter S, Gieger C, Rawal R, Mangino M, Prokopenko I, Magi R, Keskitalo K, Gudjonsdottir IH, Gretarsdottir S, Stefansson H, Thompson JR, Aulchenko YS, Nelis M, Aben KK, den Heijer M, Dirksen A, Ashraf H, Soranzo N, Valdes AM, Steves C, Uitterlinden AG, Hofman A, Tonjes A, Kovacs P, Hottenga JJ, Willemsen G, Vogelzangs N, Doring A, Dahmen N, Nitz B, Pergadia ML, Saez B, De Diego V, Lezcano V, Garcia-Prats MD, Ripatti S, Perola M, Kettunen J, Hartikainen AL, Pouta A, Laitinen J, Isohanni M, Huei-Yi S, Allen M, Krestyaninova M, Hall AS, Jones GT, van Rij AM, Mueller T, Dieplinger B, Haltmayer M, Jonsson S, Matthiasson SE, Oskarsson H, Tyrfingsson T, Kiemeney LA, Mayordomo JI, Lindholt JS, Pedersen JH, Franklin WA, Wolf H, Montgomery GW, Heath AC, Martin NG, Madden PA, Giegling I, Rujescu D, Jarvelin MR, Salomaa V, Stumvoll M, Spector TD, Wichmann HE, Metspalu A, Samani NJ, Penninx BW, Oostra BA, Boomsma DI, Tiemeier H, van Duijn CM, Kaprio J, Gulcher JR, Consortium E, McCarthy MI, Peltonen L, Thorsteinsdottir U, Stefansson K. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet 2010; 42:448-453

573. Tobacco, Genetics C. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat Genet 2010; 42:441-447

574. van Diemen CC, Postma DS, Aulchenko YS, Snijders PJ, Oostra BA, van Duijn CM, Boezen HM. Novel strategy to identify genetic risk factors for COPD severity: a genetic isolate. Eur Respir J 2010; 35:768-775

575. van Schie MC, de Maat MP, Isaacs A, van Duijn CM, Deckers JW, Dippel DW, Leebeek FW. Variation in the von Willebrand Factor gene is associated with VWF levels and with the risk of cardiovascular disease. Blood 2010;

576. Vergeer M, Boekholdt SM, Sandhu MS, Ricketts SL, Wareham NJ, Brown MJ, de Faire U, Leander K, Gigante B, Kavousi M, Hofman A, Uitterlinden AG, van Duijn CM, Witteman JC, Jukema JW, Schadt EE, van der Schoot E, Kastelein JJ, Khaw KT, Dullaart RP, van Tol A, Trip MD, Dallinga-Thie GM. Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility. Circulation 2010; 122:470-477

577. Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segre AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Bengtsson Bostrom K, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU,

Johnson PR, Jorgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proenca C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparso T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, investigators M, Consortium G. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010; 42:579-589

578. Waterworth DM, Ricketts SL, Song K, Chen L, Zhao JH, Ripatti S, Aulchenko YS, Zhang W, Yuan X, Lim N, Luan J, Ashford S, Wheeler E, Young EH, Hadley D, Thompson JR, Braund PS, Johnson T, Struchalin M, Surakka I, Luben R, Khaw KT, Rodwell SA, Loos RJ, Boekholdt SM, Inouye M, Deloukas P, Elliott P, Schlessinger D, Sanna S, Scuteri A, Jackson A, Mohlke KL, Tuomilehto J, Roberts R, Stewart A, Kesaniemi YA, Mahley RW, Grundy SM, Wellcome Trust Case Control C, McArdle W, Cardon L, Waeber G, Vollenweider P, Chambers JC, Boehnke M, Abecasis GR, Salomaa V, Jarvelin MR, Ruokonen A, Barroso I, Epstein SE, Hakonarson HH, Rader DJ, Reilly MP, Witteman JC, Hall AS, Samani NJ, Strachan DP, Barter P, van Duijn CM, Kooner JS, Peltonen L, Wareham NJ, McPherson R, Mooser V, Sandhu MS. Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol 2010; 30:2264-2276

579. Yang Q, Kottgen A, Dehghan A, Smith AV, Glazer NL, Chen MH, Chasman DI, Aspelund T, Eiriksdottir G, Harris TB, Launer L, Nalls M, Hernandez D, Arking DE, Boerwinkle E, Grove ML, Li M, Linda Kao WH, Chonchol M, Haritunians T, Li G, Lumley T, Psaty BM, Shlipak M, Hwang SJ, Larson MG, O'Donnell CJ, Upadhyay A, van Duijn CM, Hofman A, Rivadeneira F, Stricker B, Uitterlinden AG, Pare G, Parker AN, Ridker PM, Siscovick DS, Gudnason V, Witteman JC, Fox CS, Coresh J. Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circ Cardiovasc Genet 2010; 3:523-530

580. Yasuno K, Bilguvar K, Bijlenga P, Low SK, Krischek B, Auburger G, Simon M, Krex D, Arlier Z, Nayak N, Ruigrok YM, Niemela M, Tajima A, von und zu Fraunberg M, Doczi T, Wirjatijasa F, Hata A, Blasco J, Oszvald A, Kasuya H, Zilani G, Schoch B, Singh P, Stuer C, Risselada R, Beck J, Sola T, Ricciardi F, Aromaa A, Illig T, Schreiber S, van Duijn CM, van den Berg LH, Perret C, Proust C, Roder C, Ozturk AK, Gaal E, Berg D, Geisen C, Friedrich CM, Summers P, Frangi AF, State MW, Wichmann HE, Breteler MM, Wijmenga C, Mane S, Peltonen L, Elio V, Sturkenboom MC, Lawford P, Byrne J, Macho J, Sandalcioglu EI, Meyer B, Raabe A, Steinmetz H, Rufenacht D, Jaaskelainen JE, Hernesniemi J, Rinkel GJ, Zembutsu H, Inoue I, Palotie A, Cambien F, Nakamura Y, Lifton RP, Gunel M. Genome-wide association study of intracranial aneurysm identifies three new risk loci. Nat Genet 2010; 42:420-425

581. Zillikens MC, Uitterlinden AG, van Leeuwen JP, Berends AL, Henneman P, van Dijk KW, Oostra BA, van Duijn CM, Pols HA, Rivadeneira F. The role of body mass index, insulin, and adiponectin in the relation between fat distribution and bone mineral density. Calcif Tissue Int 2010; 86:116-125

582. Zillikens MC, van Meurs JB, Rivadeneira F, Hofman A, Oostra BA, Sijbrands EJ, Witteman JC, Pols HA, van Duijn CM, Uitterlinden AG. Interactions between dietary vitamin E intake and SIRT1 genetic variation influence body mass index. Am J Clin Nutr 2010; 91:1387-1393

583. Zillikens MC, van Meurs JB, Rivadeneira F, Amin N, Hofman A, Oostra BA, Sijbrands EJ, Witteman JC, Pols HA, van Duijn CM, Uitterlinden AG. SIRT1 genetic variation is related to BMI and risk of obesity. Diabetes 2009 Dec;58:2828-34

584. Zorkoltseva IV, Aulchenko YS, van Duijn CM, Axenovich TI. Ped_Outlier software for automatic identification of within-family outliers. Comput Biol Chem 2010; 34:242-243

585. Zubakov D, Liu F, van Zelm MC, Vermeulen J, Oostra BA, van Duijn CM, Driessen GJ, van Dongen JJ, Kayser M, Langerak AW. Estimating human age from T-cell DNA rearrangements. Curr Biol 2010; 20:R970-971

2011

586. Amin N, Schuur M, Gusareva ES, Isaacs A, Aulchenko YS, Kirichenko AV, Zorkoltseva IV, Axenovich TI, Oostra BA, Janssens AC, van Duijn CM. A genome-wide linkage study of individuals with high scores on NEO personality traits. Mol Psychiatry. 2011

587. Amin N, Byrne E, Johnson J, Chenevix-Trench G, Walter S, Nolte IM, kConFab I, Vink JM, Rawal R, Mangino M, Teumer A, Keers JC, Verwoert G, Baumeister S, Biffar R, Petersmann A, Dahmen N, Doering A, Isaacs A, Broer L, Wray NR, Montgomery GW, Levy D, Psaty BM, Gudnason V, Chakravarti A, Sulem P, Gudbjartsson DF, Kiemeney LA, Thorsteinsdottir U, Stefansson K, van Rooij FJ, Aulchenko YS, Hottenga JJ, Rivadeneira FR, Hofman A, Uitterlinden AG, Hammond CJ, Shin SY, Ikram A, Witteman JC, Janssens AC, Snieder H, Tiemeier H, Wolfenbuttel BH, Oostra BA, Heath AC, Wichmann E, Spector TD, Grabe HJ, Boomsma DI, Martin NG, van Duijn CM. Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Mol Psychiatry. 2011

588. Bis JC, Kavousi M, Franceschini N, Isaacs A, Abecasis GR, Schminke U, Post WS, Smith AV, Cupples LA, Markus HS, Schmidt R, Huffman JE, Lehtimäki T, Baumert J, Münzel T, Heckbert SR, Dehghan A, North K, Oostra B, Bevan S, Stoegerer EM, Hayward C, Raitakari O, Meisinger C, Schillert A, Sanna S, Völzke H, Cheng YC, Thorsson B, Fox CS, Rice K, Rivadeneira F, Nambi V, Halperin E, Petrovic KE, Peltonen L, Wichmann HE, Schnabel RB, Dörr M, Parsa A, Aspelund T, Demissie S, Kathiresan S, Reilly MP; the CARDIoGRAM Consortium, Taylor K, Uitterlinden A, Couper DJ, Sitzer M, Kähönen M, Illig T, Wild PS, Orru M, Lüdemann J, Shuldiner AR, Eiriksdottir G, White CC, Rotter JI, Hofman A, Seissler J, Zeller T, Usala G, Ernst F, Launer LJ, D'Agostino RB Sr, O'Leary DH, Ballantyne C, Thiery J, Ziegler A, Lakatta EG, Chilukoti RK, Harris TB, Wolf PA, Psaty BM, Polak JF, Li X, Rathmann W, Uda M, Boerwinkle E, Klopp N, Schmidt H, Wilson JF, Viikari J, Koenig W, Blankenberg S, Newman AB, Witteman J, Heiss G, van Duijn C, Scuteri A, Homuth G, Mitchell BD, Gudnason V, O'Donnell CJ. Meta-analysis of genome-wide association studies

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591. Brugts JJ, Isaacs A, de Maat MP, Boersma E, van Duijn CM, Akkerhuis KM, Uitterlinden AG, Witteman JC, Cambien F, Ceconi C, Remme W, Bertrand M, Ninomiya T, Harrap S, Chalmers J, Macmahon S, Fox K, Ferrari R, Simoons ML, Danser AJ. A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with vascular disease and healthy individuals. J Hypertens. 2011; 29:509-519

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593. Coppus AM, Schuur M, Vergeer J, Janssens AC, Oostra BA, Verbeek MM, van Duijn CM. Plasma β amyloid and the risk of Alzheimer's disease in Down syndrome. Neurobiol Aging. 2011 Sep 27

594. de Keyser CE, Eijgelsheim M, Hofman A, Sijbrands EJ, Maitland-van der Zee AH, van Duijn CM, Uitterlinden AG, Witteman JC, Ch Stricker BH. Single nucleotide polymorphisms in genes that are associated with a modified response to statin therapy: the Rotterdam Study. Pharmacogenomics J. 2011; 11:72-80

595. Deelen J, Beekman M, Uh HW, Helmer Q, Kuningas M, Christiansen L, Kremer D, van der Breggen R, Suchiman HE, Lakenberg N, van den Akker EB, Passtoors WM, Tiemeier H, van Heemst D, de Craen AJ, Rivadeneira F, de Geus EJ, Perola M, van der Ouderaa FJ, Gunn DA, Boomsma DI, Uitterlinden AG, Christensen K, van Duijn CM, Heijmans BT, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE. Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited. Aging Cell. 2011; 10:686-698

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600. Geelhoed JJ, van Duijn C, van Osch-Gevers L, Steegers EA, Hofman A, Helbing WA, Jaddoe VW. Glucocorticoid receptor-9beta polymorphism is associated with systolic blood pressure and heart growth during early childhood. The Generation R Study. Early Hum Dev. 2011 Feb;87(2):97-102

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603. Hamamy H, Antonarakis SE, Cavalli-Sforza LL, Temtamy S, Romeo G, Kate LP, Bennett RL, Shaw A, Megarbane A, van Duijn C, Bathija H, Fokstuen S, Engel E, Zlotogora J, Dermitzakis E, Bottani A, Dahoun S, Morris MA, Arsenault S, Aglan MS, Ajaz M, Alkalamchi A, Alnaqeb D, Alwasiyah MK, Anwer N, Awwad R, Bonnefin M, Corry P, Gwanmesia L, Karbani GA, Mostafavi M, Pippucci T, Ranza-Boscardin E, Reversade B, Sharif SM, Teeuw ME, Bittles AH. Consanguineous marriages, pearls and perils: Geneva International Consanguinity Workshop Report. Genet Med. 2011 Sep;13:841-7

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605. Ho L, van Leeuwen R, Witteman JC, van Duijn CM, Uitterlinden AG, Hofman A, de Jong PT, Vingerling JR, Klaver CC. Reducing the genetic risk of age-related macular degeneration with dietary antioxidants, zinc, and omega-3 fatty acids: the Rotterdam study. Arch Ophthalmol. 2011; 129:758-766

606. Hofman A, van Duijn CM, Franco OH, Ikram MA, Janssen HL, Klaver CC, Kuipers EJ, Nijsten TE, Stricker BH, Tiemeier H, Uitterlinden AG, Vernooij MW, Witteman JC. The Rotterdam Study: 2012 objectives and design update. Eur J Epidemiol. 2011; 26:657-686

607. Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D, Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H, Warden D, Wilcock G, Love S, Kehoe PG, Hooper NM, Vardy ER, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, Maier W, Jessen F, Ruther E, Schurmann B, Heun R, Kolsch H, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frolich L, Hampel H, Gallacher J, Hull M, Rujescu D, Giegling I, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Muhleisen TW, Nothen MM, Moebus S, Jockel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC, Alzheimer's Disease Neuroimaging I, van Duijn CM, Breteler MM, Ikram MA, DeStefano AL, Fitzpatrick AL, Lopez O, Launer LJ, Seshadri S, consortium C, Berr C, Campion D, Epelbaum J, Dartigues JF, Tzourio C, Alperovitch A, Lathrop M, consortium E, Feulner TM, Friedrich P, Riehle C, Krawczak M, Schreiber S, Mayhaus M, Nicolhaus S, Wagenpfeil S, Steinberg S, Stefansson H, Stefansson K, Snaedal J, Bjornsson S, Jonsson PV, Chouraki V, Genier-Boley B, Hiltunen M, Soininen H, Combarros O, Zelenika D, Delepine M, Bullido MJ, Pasquier F, Mateo I, Frank-Garcia A, Porcellini E, Hanon O, Coto E, Alvarez V, Bosco P, Siciliano G, Mancuso M, Panza F, Solfrizzi V, Nacmias B, Sorbi S, Bossu P, Piccardi P, Arosio B, Annoni G, Seripa D, Pilotto A, Scarpini E, Galimberti D, Brice A, Hannequin D, Licastro F, Jones L, Holmans PA, Jonsson T, Riemenschneider M, Morgan K, Younkin SG, Owen MJ, O'Donovan M, Amouyel P, Williams J. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet. 2011; 43:429-435

608. Holmes MV, Newcombe P, Hubacek JA, Sofat R, Ricketts SL, Cooper J, Breteler MM, Bautista LE, Sharma P, Whittaker JC, Smeeth L, Fowkes FG, Algra A, Shmeleva V, Szolnoki Z, Roest M, Linnebank M, Zacho J, Nalls MA, Singleton AB, Ferrucci L, Hardy J, Worrall BB, Rich SS, Matarin M, Norman PE, Flicker L, Almeida OP, van Bockxmeer FM, Shimokata H, Khaw KT, Wareham NJ, Bobak M, Sterne JA, Smith GD, Talmud PJ, van Duijn C, Humphries SE, Price JF, Ebrahim S, Lawlor DA, Hankey GJ, Meschia JF, Sandhu MS, Hingorani AD, Casas JP. Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. Lancet. 2011 Aug 13;378(9791):584-94

609. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Eur J Hum Genet. 2011; 19:833-836

610. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ, Group G. Strengthening the reporting of Genetic Risk Prediction Studies: the GRIPS statement. Genet Med. 2011; 13:453-456

611. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ, Group G. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Eur J Clin Invest. 2011; 41:1004-1009

612. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ, Group G. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Eur J Epidemiol. 2011; 26:255-259

613. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ, Group G. Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement. PLoS Med. 2011; 8:e1000420

614. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ, Group G. Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement. J Clin Epidemiol. 2011; 64:843-847

615. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ, Group G. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. BMJ. 2011; 342:d631

616. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ, the GG. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Genome Med. 2011; 3:16

617. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ, Group G. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Circ Cardiovasc Genet. 2011; 4:206-209

618. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ, Group G. Strengthening the reporting of genetic risk prediction studies: The GRIPS Statement. Ann Intern Med. 2011; 154:421-425

619. Janssens AC, Henneman L, Detmar SB, Khoury MJ, Steyerberg EW, Eijkemans MJ, Mushkudiani N, Oostra BA, van Duijn CM, Mackenbach JP. Accuracy of self-reported family history is strongly influenced by the accuracy of self-reported personal health status of relatives. J Clin Epidemiol. 2011

620. Janssens AC, Ioannidis JP, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J, Gwinn M, Hlatky MA, Janes H, Kraft P, Melillo S, O'Donnell CJ, Pencina MJ, Ransohoff D, Schully SD, Seminara D, Winn DM, Wright CF, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Clin Invest. 2011; 41:1010-103

621. Janssens AC, Ioannidis JP, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J, Gwinn M, Hlatky MA, Janes H, Kraft P, Melillo S, O'Donnell CJ, Pencina MJ, Ransohoff D, Schully SD, Seminara D, Winn DM, Wright CF, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Epidemiol. 2011; 26:313-337

622. Janssens AC, Ioannidis JP, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J, Gwinn M, Hlatky MA, Janes H, Kraft P, Melillo S, O'Donnell CJ, Pencina MJ, Ransohoff D, Schully SD, Seminara D, Winn DM, Wright CF, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration. J Clin Epidemiol. 2011; 64:e1-e22

623. Janssens AC, Ioannidis JP, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J, Gwinn M, Hlatky MA, Janes H, Kraft P, Melillo S,

O'Donnell CJ, Pencina MJ, Ransohoff D, Schully SD, Seminara D, Winn DM, Wright CF, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Hum Genet. 2011; 19:18 p preceding 494

624. Johnson AD, Newton-Cheh C, Chasman DI, Ehret GB, Johnson T, Rose L, Rice K, Verwoert GC, Launer LJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, Caulfield M, van Duijn CM, Ridker PM, Munroe PB, Levy D, Cohorts for H, Aging Research in Genomic Epidemiology C, Global BC, Women's Genome Health S. Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals. Hypertension. 2011; 57:903-910

625. Kanoni S, Nettleton JA, Hivert MF, Ye Z, van Rooij FJ, Shungin D, Sonestedt E, Ngwa JS, Wojczynski MK, Lemaitre RN, Gustafsson S, Anderson JS, Tanaka T, Hindy G, Saylor G, Renstrom F, Bennett AJ, van Duijn CM, Florez JC, Fox CS, Hofman A, Hoogeveen RC, Houston DK, Hu FB, Jacques PF, Johansson I, Lind L, Liu Y, McKeown N, Ordovas J, Pankow JS, Sijbrands EJ, Syvanen AC, Uitterlinden AG, Yannakoulia M, Zillikens MC, the MI, Wareham NJ, Prokopenko I, Bandinelli S, Forouhi NG, Cupples LA, Loos RJ, Hallmans G, Dupuis J, Langenberg C, Ferrucci L, Kritchevsky SB, McCarthy MI, Ingelsson E, Borecki IB, Witteman JC, Orho-Melander M, Siscovick DS, Meigs JB, Franks PW, Dedoussis GV. Total Zinc Intake May Modify the Glucose-Raising Effect of a Zinc Transporter (SLC30A8) Variant: A 14-Cohort Meta-analysis. Diabetes. 2011; 60:2407-2416

626. Khor CC, Ramdas WD, Vithana EN, Cornes BK, Sim X, Tay WT, Saw SM, Zheng Y, Lavanya R, Wu R, Wang JJ, Mitchell P, Uitterlinden AG, Rivadeneira F, Teo YY, Chia KS, Seielstad M, Hibberd M, Vingerling JR, Klaver CC, Jansonius NM, Tai ES, Wong TY, van Duijn CM, Aung T. Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area. Hum Mol Genet. 2011; 20:1864-1872

627. Kilpelainen TO, Zillikens MC, Stancakova A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS, Luan J, Vandenput L, Styrkarsdottir U, Zhou Y, Smith AV, Zhao JH, Amin N, Vedantam S, Shin SY, Haritunians T, Fu M, Feitosa MF, Kumari M, Halldorsson BV, Tikkanen E, Mangino M, Hayward C, Song C, Arnold AM, Aulchenko YS, Oostra BA, Campbell H, Cupples LA, Davis KE, Doring A, Eiriksdottir G, Estrada K, Fernandez-Real JM, Garcia M, Gieger C, Glazer NL, Guiducci C, Hofman A, Humphries SE, Isomaa B, Jacobs LC, Jula A, Karasik D, Karlsson MK, Khaw KT, Kim LJ, Kivimaki M, Klopp N, Kuhnel B, Kuusisto J, Liu Y, Ljunggren O, Lorentzon M, Luben RN, McKnight B, Mellstrom D, Mitchell BD, Mooser V, Moreno JM, Mannisto S, O'Connell JR, Pascoe L, Peltonen L, Peral B, Perola M, Psaty BM, Salomaa V, Savage DB, Semple RK, Skaric-Juric T, Sigurdsson G, Song KS, Spector TD, Syvanen AC, Talmud PJ, Thorleifsson G, Thorsteinsdottir U, Uitterlinden AG, van Duijn CM, Vidal-Puig A, Wild SH, Wright AF, Clegg DJ, Schadt E, Wilson JF, Rudan I, Ripatti S, Borecki IB, Shuldiner AR, Ingelsson E, Jansson JO, Kaplan RC, Gudnason V, Harris TB, Groop L, Kiel DP, Rivadeneira F, Walker M, Barroso I, Vollenweider P, Waeber G, Chambers JC, Kooner JS, Soranzo N, Hirschhorn JN, Stefansson K, Wichmann HE, Ohlsson C, O'Rahilly S, Wareham NJ, Speliotes EK, Fox CS, Laakso M, Loos RJ. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet. 2011; 43:753-760

628. Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, Wolf C, Ising M, Schreiber S, Czisch M, Muller MB, Uhr M, Bettecken T, Becker A, Schramm J, Rietschel

M, Maier W, Bradley B, Ressler KJ, Nothen MM, Cichon S, Craig IW, Breen G, Lewis CM, Hofman A, Tiemeier H, van Duijn CM, Holsboer F, Muller-Myhsok B, Binder EB. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron. 2011; 70:252-265

629. Kornfeld JW, Isaacs A, Vitart V, Pospisilik JA, Meitinger T, Gyllensten U, Wilson JF, Rudan I, Campbell H, Penninger JM, Sexl V, Moriggl R, van Duijn C, Pramstaller PP, Hicks AA. Variants in STAT5B associate with serum TC and LDL-C levels. J Clin Endocrinol Metab. 2011 Sep;96(9):E1496-501

630. Kundu S, Aulchenko YS, van Duijn CM, Janssens AC. PredictABEL: an R package for the assessment of risk prediction models. Eur J Epidemiol. 2011; 26:261-264

631. Kuningas M, Altmae S, Uitterlinden AG, Hofman A, van Duijn CM, Tiemeier H. The relationship between fertility and lifespan in humans. Age (Dordr). 2011

632. Kuningas M, McQuillan R, Wilson JF, Hofman A, van Duijn CM, Uitterlinden AG, Tiemeier H. Runs of homozygosity do not influence survival to old age. PLoS One. 2011; 6:e22580

633. Kuningas M, Estrada K, Hsu YH, Nandakumar K, Uitterlinden AG, Lunetta KL, van Duijn CM, Karasik D, Hofman A, Murabito J, Rivadeneira F, Kiel DP, Tiemeier H. Large common deletions associate with mortality at old age. Hum Mol Genet. 2011

634. Ligthart L, de Vries B, Smith AV, Ikram MA, Amin N, Hottenga JJ, Koelewijn SC, Kattenberg VM, de Moor MH, Janssens AC, Aulchenko YS, Oostra BA, de Geus EJ, Smit JH, Zitman FG, Uitterlinden AG, Hofman A, Willemsen G, Nyholt DR, Montgomery GW, Terwindt GM, Gudnason V, Penninx BW, Breteler M, Ferrari MD, Launer LJ, van Duijn CM, van den Maagdenberg AM, Boomsma DI. Meta-analysis of genome-wide association for migraine in six population-based European cohorts. Eur J Hum Genet. 2011; 19:901-907

635. Maitland-van der Zee AH, van Wieren-de Wijer DB, de Boer A, Kroon AA, de Leeuw PW, Schiffers P, Janssen RG, Psaty BM, van Duijn CM, Stricker BH, Klungel OH. Genetic variation in the renin--angiotensin system, use of renin--angiotensin system inhibitors and the risk of myocardial infarction. J Renin Angiotensin Aldosterone Syst. 2011; 12:208-21

636. Mook-Kanamori DO, Ay L, Hofman A, van Duijn CM, Moll HA, Raat H, Hokken-Koelega AC, Jaddoe VW. No association of obesity gene FTO with body composition at the age of 6 months. The Generation R Study. J Endocrinol Invest. 2011; 34:16-20

637. Nalls MA, Couper DJ, Tanaka T, van Rooij FJ, Chen MH, Smith AV, Toniolo D, Zakai NA, Yang Q, Greinacher A, Wood AR, Garcia M, Gasparini P, Liu Y, Lumley T, Folsom AR, Reiner AP, Gieger C, Lagou V, Felix JF, Volzke H, Gouskova NA, Biffi A, Doring A, Volker U, Chong S, Wiggins KL, Rendon A, Dehghan A, Moore M, Taylor K, Wilson JG, Lettre G, Hofman A, Bis JC, Pirastu N, Fox CS, Meisinger C, Sambrook J, Arepalli S, Nauck M, Prokisch H, Stephens J, Glazer NL, Cupples LA, Okada Y, Takahashi A, Kamatani Y, Matsuda K, Tsunoda T, Kubo M, Nakamura Y, Yamamoto K, Kamatani N, Stumvoll M, Tonjes A, Prokopenko I, Illig T, Patel KV, Garner SF, Kuhnel B, Mangino M, Oostra BA, Thein SL, Coresh J, Wichmann HE, Menzel S, Lin J, Pistis G, Uitterlinden AG, Spector TD, Teumer A, Eiriksdottir G, Gudnason V, Bandinelli S, Frayling TM, Chakravarti A, van Duijn CM, Melzer D, Ouwehand WH, Levy D, Boerwinkle E, Singleton AB, Hernandez DG, Longo DL, Soranzo N, Witteman JC, Psaty BM, Ferrucci L, Harris TB, O'Donnell CJ,

Ganesh SK. Multiple loci are associated with white blood cell phenotypes. PLoS Genet. 2011; 7:e1002113

638. Obermann-Borst SA, Isaacs A, Younes Z, van Schaik RH, van der Heiden IP, van Duyn CM, Steegers EA, Steegers-Theunissen RP. General maternal medication use, folic acid, the MDR1 C3435T polymorphism, and the risk of a child with a congenital heart defect. Am J Obstet Gynecol. 2011 Mar;204:236

639. Ramdas WD, Amin N, van Koolwijk LM, Janssens AC, Demirkan A, de Jong PT, Aulchenko YS, Wolfs RC, Hofman A, Rivadeneira F, Uitterlinden AG, Oostra BA, Lemij HG, Klaver CC, Vingerling JR, Jansonius NM, van Duijn CM. Genetic architecture of open angle glaucoma and related determinants. J Med Genet. 2011; 48:190-196

640. Ramdas WD, van Koolwijk LM, Cree AJ, Janssens AC, Amin N, de Jong PT, Wolfs RC, Gibson J, Kirwan JF, Hofman A, Rivadeneira F, Oostra BA, Uitterlinden AG, Ennis S, Lotery AJ, Lemij HG, Klaver CC, Vingerling JR, Jansonius NM, van Duijn CM. Clinical Implications of Old and New Genes for Open-Angle Glaucoma. Ophthalmology. 2011

641. Ramdas WD, van Koolwijk LM, Lemij HG, Pasutto F, Cree AJ, Thorleifsson G, Janssen SF, Jacoline TB, Amin N, Rivadeneira F, Wolfs RC, Walters GB, Jonasson F, Weisschuh N, Mardin CY, Gibson J, Zegers RH, Hofman A, de Jong PT, Uitterlinden AG, Oostra BA, Thorsteinsdottir U, Gramer E, Welgen-Lussen UC, Kirwan JF, Bergen AA, Reis A, Stefansson K, Lotery AJ, Vingerling JR, Jansonius NM, Klaver CC, van Duijn CM. Common genetic variants associated with open-angle glaucoma. Hum Mol Genet. 2011; 20:2464-2471

642. Ricketts SL, Rensing KL, Holly JM, Chen L, Young EH, Luben R, Ashford S, Song K, Yuan X, Dehghan A, Wright BJ, Waterworth DM, Mooser V, Investigators G, Waeber G, Vollenweider P, Epstein SE, Burnett MS, Devaney JM, Hakonarson HH, Rader DJ, Reilly MP, Danesh J, Thompson SG, Dunning AM, van Duijn CM, Samani NJ, McPherson R, Wareham NJ, Khaw KT, Boekholdt SM, Sandhu MS. Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease. Int J Mol Epidemiol Genet. 2011; 2:261-285

643. Ruiter R, Visser LE, van Duijn CM, Ch Stricker BH. The ACE insertion/deletion polymorphism and risk of cancer, a review and meta-analysis of the literature. Curr Cancer Drug Targets. 2011; 11:421-430

644. Sanchez-Juan P, Bishop MT, Croes EA, Knight RS, Will RG, van Duijn CM, Manson JC. A polymorphism in the regulatory region of PRNP is associated with increased risk of sporadic Creutzfeldt-Jakob disease. BMC Med Genet. 2011; 12:73

645. Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivieres S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, Bilbao A, de Boer RA, Beury D, Bots ML, Breetvelt EJ, Cauchi S, Cavalcanti-Proenca C, Chambers JC, Clarke TK, Dahmen N, de Geus EJ, Dick D, Ducci F, Easton A, Edenberg HJ, Esko T, Fernandez-Medarde A, Foroud T, Freimer NB, Girault JA, Grobbee DE, Guarrera S, Gudbjartsson DF, Hartikainen AL, Heath AC, Hesselbrock V, Hofman A, Hottenga JJ, Isohanni MK, Kaprio J, Khaw KT, Kuehnel B, Laitinen J, Lobbens S, Luan J, Mangino M, Maroteaux M, Matullo G, McCarthy MI, Mueller C, Navis G, Numans ME, Nunez A, Nyholt DR, Onland-Moret CN, Oostra BA, O'Reilly PF, Palkovits M, Penninx BW,

Polidoro S, Pouta A, Prokopenko I, Ricceri F, Santos E, Smit JH, Soranzo N, Song K, Sovio U, Stumvoll M, Surakk I, Thorgeirsson TE, Thorsteinsdottir U, Troakes C, Tyrfingsson T, Tonjes A, Uiterwaal CS, Uitterlinden AG, van der Harst P, van der Schouw YT, Staehlin O, Vogelzangs N, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Whitfield JB, Wichmann EH, Willemsen G, Witteman JC, Yuan X, Zhai G, Zhao JH, Zhang W, Martin NG, Metspalu A, Doering A, Scott J, Spector TD, Loos RJ, Boomsma DI, Mooser V, Peltonen L, Stefansson K, van Duijn CM, Vineis P, Sommer WH, Kooner JS, Spanagel R, Heberlein UA, Jarvelin MR, Elliott P. Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A. 2011; 108:7119-7124

646. Schuur M, Ikram MA, van Swieten JC, Isaacs A, Vergeer-Drop JM, Hofman A, Oostra BA, Breteler MM, van Duijn CM. Cathepsin D gene and the risk of Alzheimer's disease: a population-based study and meta-analysis. Neurobiol Aging. 2011; 32:1607-1614

647. Schuur M, van Swieten JC, Schol-Gelok S, Ikram MA, Vernooij MW, Liu F, Isaacs A, de Boer R, de Koning I, Niessen WJ, Vrooman H, Oostra BA, van der Lugt A, Breteler MM, van Duijn CM. Genetic risk factors for cerebral small-vessel disease in hypertensive patients from a genetically isolated population. J Neurol Neurosurg Psychiatry. 2011; 82:41-44

648. Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G, Garcia ME, Launer LJ, Nalls MA, Clark JM, Mitchell BD, Shuldiner AR, Butler JL, Tomas M, Hoffmann U, Hwang SJ, Massaro JM, O'Donnell CJ, Sahani DV, Salomaa V, Schadt EE, Schwartz SM, Siscovick DS; NASH CRN; GIANT Consortium; MAGIC Investigators, Voight BF, Carr JJ, Feitosa MF, Harris TB, Fox CS, Smith AV, Kao WH, Hirschhorn JN, Borecki IB; GOLD Consortium. Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet. 2011 Mar;7(3):e1001324.

649. Ida Surakka, Aaron Isaacs, Lennart C. Karssen, Pirkka-Pekka P. Laurila, Rita P. S. Middelberg, Emmi Tikkanen, Janina S. Ried, Claudia Lamina, Massimo Mangino, Wilmar Igl, Jouke-Jan Hottenga, Vasiliki Lagou, Pim van der Harst, Irene Mateo Leach, Tõnu Esko, Zoltán Kutalik, Nicholas W. Wainwright, Maksim V. Struchalin, Antti-Pekka Sarin, Antti J. Kangas, Jorma S. Viikari, Markus Perola, Taina Rantanen, Ann-Kristin Petersen, Pasi Soininen, Åsa Johansson, Nicole Soranzo, Andrew C. Heath, Theodore Papamarkou, Inga Prokopenko, Anke Tönjes, Florian Kronenberg, Angela Döring, Fernando Rivadeneira, Grant W. Montgomery, John B. Whitfield, Mika Kähönen, Terho Lehtimäki, Nelson B. Freimer, Gonneke Willemsen, Eco J. C. de Geus, Aarno Palotie, Manj S. Sandhu, Dawn M. Waterworth, Andres Metspalu, Michael Stumvoll, André G. Uitterlinden, Antti Jula, Gerjan Navis, Cisca Wijmenga, Bruce H. R. Wolffenbuttel, Marja-Riitta Taskinen, Mika Ala-Korpela, Jaakko Kaprio, Kirsten O. Kyvik, Dorret I. Boomsma, Nancy L. Pedersen, Ulf Gyllensten, James F. Wilson, Igor Rudan, Harry Campbell, Peter P. Pramstaller, Tim D. Spector, Jacqueline C. M. Witteman, Johan G. Eriksson, Veikko Salomaa, Ben A. Oostra, Olli T. Raitakari, H.-Erich Wichmann, Christian Gieger, Marjo-Riitta Järvelin, Nicholas G. Martin, Albert Hofman, Mark I. McCarthy, Leena Peltonen, Cornelia M. van Duijn, Yurii S. Aulchenko, Samuli Ripatti, for the ENGAGE Consortium Ben A Oostra ... A Genome-Wide Screen for Interactions Reveals a New Locus on 4p15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol PLoS Genetics: Research Article, published 20 Oct 2011

650. The International Consortium for Blood Pressure Genome-Wide Association S, Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Hua Zhao J, Aulchenko Y, Heath S, Sober S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Jin Go M, van der Harst P, Hong Linda Kao W, Sjogren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Hoang Nguyen KD, Lehtimaki T, Matullo G, Wu Y, Gaunt TR, Charlotte Onland-Moret N, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li Y, Hunter Young J, Bis JC, Kahonen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Hoffman Bolton JA, Kottgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grassler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Soler Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Maria Corsi A, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Shin Cho Y, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang W, Hedblad B, Nilsson P, Davey Smith G, Wong A, Narisu N, Stancakova A, Raffel LJ, Yao J, Kathiresan S, O'Donnell CJ, Schwartz SM, Arfan Ikram M, Longstreth Jr WT, Mosley TH, Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Radha Mani K, Yajnik CS, Hofman A, Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikainen LP, Soininen P, Tukiainen T, Wurtz P, Twee-Hee Ong R, Dorr M, Kroemer HK, Volker U, Volzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G, Meschia JF, Nalls MA, Sharma P, Terzic J, Kranthi Kumar MV, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Gerald RFF, Charchar FJ, Schwarz PE, Hayward C, Guo X, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Ganesh SK, Wong TY, Shyong Tai E, Cooper RS, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu X, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJ, Altshuler D, Loos RJ, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JC, Hartikainen AL, Beckmann JS, Boerwinkle E, Vasan RS, Boehnke M, Larson MG, Jarvelin MR, Psaty BM, Abecasis GR, Chakravarti A, Elliott P, van Duijn CM, Newton-Cheh C, Levy D, Caulfield MJ, Johnson T. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011

651. van Hoek M, van Herpt TW, Dehghan A, Hofman A, Lieverse AG, van Duijn CM, Witteman JC, Sijbrands EJ. Association of an APOC3 promoter variant with type 2 diabetes risk and need for insulin treatment in lean persons. Diabetologia. 2011; 54:1360-1367

652. van Schie MC, de Maat MP, Isaacs A, van Duijn CM, Deckers JW, Dippel DW, Leebeek FW. Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular disease. Blood. 2011; 117:1393-1399

653. van Zitteren M, van der Net JB, Kundu S, Freedman AN, van Duijn CM, Janssens AC. Genome-based prediction of breast cancer risk in the general population: a modeling study based on meta-analyses of genetic associations. Cancer Epidemiol Biomarkers Prev. 2011; 20:9-22

654. Velders FP, Kuningas M, Kumari M, Dekker MJ, Uitterlinden AG, Kirschbaum C, Hek K, Hofman A, Verhulst FC, Kivimaki M, van Duijn CM, Walker BR, Tiemeier H. Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach. Psychoneuroendocrinology. 2011; 36:1053-1061

655. Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M, Rice KM, Henneman P, Smith AV, Ehret GB, Amin N, Larson MG, Mooser V, Hadley D, Dorr M, Bis JC, Aspelund T, Esko T, Janssens AC, Zhao JH, Heath S, Laan M, Fu J, Pistis G, Luan J, Arora P, Lucas G, Pirastu N, Pichler I, Jackson AU, Webster RJ, Zhang F, Peden JF, Schmidt H, Tanaka T, Campbell H, Igl W, Milaneschi Y, Hottenga JJ, Vitart V, Chasman DI, Trompet S, Bragg-Gresham JL, Alizadeh BZ, Chambers JC, Guo X, Lehtimaki T, Kuhnel B, Lopez LM, Polasek O, Boban M, Nelson CP, Morrison AC, Pihur V, Ganesh SK, Hofman A, Kundu S, Mattace-Raso FU, Rivadeneira F, Sijbrands EJ, Uitterlinden AG, Hwang SJ, Vasan RS, Wang TJ, Bergmann S, Vollenweider P, Waeber G, Laitinen J, Pouta A, Zitting P, McArdle WL, Kroemer HK, Volker U, Volzke H, Glazer NL, Taylor KD, Harris TB, Alavere H, Haller T, Keis A, Tammesoo ML, Aulchenko Y, Barroso I, Khaw KT, Galan P, Hercberg S, Lathrop M, Eyheramendy S, Org E, Sober S, Lu X, Nolte IM, Penninx BW, Corre T, Masciullo C, Sala C, Groop L, Voight BF, Melander O, O'Donnell CJ, Salomaa V, d'Adamo AP, Fabretto A, Faletra F, Ulivi S, Del Greco MF, Facheris M, Collins FS, Bergman RN, Beilby JP, Hung J, Musk AW, Mangino M, Shin SY, Soranzo N, Watkins H, Goel A, Hamsten A, Gider P, Loitfelder M, Zeginigg M, Hernandez D, Najjar SS, Navarro P, Wild SH, Corsi AM, Singleton A, de Geus EJ, Willemsen G, Parker AN, Rose LM, Buckley B, Stott D, Orru M, Uda M, LifeLines Cohort S, van der Klauw MM, Zhang W, Li X, Scott J, Chen YD, Burke GL, Kahonen M, Viikari J, Doring A, Meitinger T, Davies G, Starr JM, Emilsson V, Plump A, Lindeman JH, Hoen PA, Konig IR, EchoGen c, Felix JF, Clarke R, Hopewell JC, Ongen H, Breteler M, Debette S, Destefano AL, Fornage M, AortaGen C, Mitchell GF, Group CCHFW, Smith NL, KidneyGen c, Holm H, Stefansson K, Thorleifsson G, Thorsteinsdottir U, consortium CK, Cardiogenics c, CardioGram, Samani NJ, Preuss M, Rudan I, Hayward C, Deary IJ, Wichmann HE, Raitakari OT, Palmas W, Kooner JS, Stolk RP, Jukema JW, Wright AF, Boomsma DI, Bandinelli S, Gyllensten UB, Wilson JF, Ferrucci L, Schmidt R, Farrall M, Spector TD, Palmer LJ, Tuomilehto J, Pfeufer A, Gasparini P, Siscovick D, Altshuler D, Loos RJ, Toniolo D, Snieder H, Gieger C, Meneton P, Wareham NJ, Oostra BA, Metspalu A, Launer L, Rettig R, Strachan DP, Beckmann JS, Witteman JC, Erdmann J, van Dijk KW, Boerwinkle E, Boehnke M, Ridker PM, Jarvelin MR, Chakravarti A, Abecasis GR, Gudnason V, Newton-Cheh C, Levy D, Munroe PB, Psaty BM, Caulfield MJ, Rao DC, Tobin MD, Elliott P, van Duijn CM. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet. 2011

656. Walter S, Atzmon G, Demerath EW, Garcia ME, Kaplan RC, Kumari M, Lunetta KL, Milaneschi Y, Tanaka T, Tranah GJ, Völker U, Yu L, Arnold A, Benjamin EJ, Biffar R, Buchman AS, Boerwinkle E, Couper D, De Jager PL, Evans DA, Harris TB, Hoffmann W, Hofman A, Karasik D, Kiel DP, Kocher T, Kuningas M, Launer LJ, Lohman KK, Lutsey PL, Mackenbach J, Marciante K, Psaty BM, Reiman EM, Rotter JI, Seshadri S, Shardell MD, Smith AV, van Duijn C, Walston J, Zillikens MC, Bandinelli S, Baumeister SE, Bennett DA, Ferrucci L, Gudnason V, Kivimaki M, Liu Y, Murabito JM, Newman AB, Tiemeier H, Franceschini N. A genome-wide association study of aging. Neurobiol Aging. 2011 Nov;32:2109

657. Willems SM, Mihaescu R, Sijbrands EJ, van Duijn CM, Janssens AC.A Methodological Perspective on Genetic Risk Prediction Studies in Type 2 Diabetes: Recommendations for Future Research. Curr Diab Rep. 2011 Sep 27

658. Yu Y, Bhangale TR, Fagerness J, Ripke S, Thorleifsson G, Tan PL, Souied EH, Richardson AJ, Merriam JE, Buitendijk GH, Reynolds R, Raychaudhuri S, Chin KA, Sobrin L, Evangelou E, Lee PH, Lee AY, Leveziel N, Zack DJ, Campochiaro B, Campochiaro P, Smith RT, Barile GR, Guymer RH, Hogg R, Chakravarthy U, Robman LD, Gustafsson O, Sigurdsson H, Ortmann W, Behrens TW, Stefansson K, Uitterlinden AG, van Duijn CM, Vingerling JR, Klaver CC, Allikmets R, Brantley MA, Jr., Baird PN, Katsanis N, Thorsteinsdottir U, Ioannidis JP, Daly MJ, Graham RR, Seddon JM. Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Hum Mol Genet. 2011; 20:3699-3709

659. Zaboli G, Ameur A, Igl W, Johansson A, Hayward C, Vitart V, Campbell S, Zgaga L, Polasek O, Schmitz G, van Duijn C, Oostra B, Pramstaller P, Hicks A, Meitinger T, Rudan I, Wright A, Wilson JF, Campbell H, Gyllensten U. Sequencing of high-complexity DNA pools for identification of nucleotide and structural variants in regions associated with complex traits. Eur J Hum Genet. 2011 Aug 3

2012

660. Ameur A, Enroth S, Johansson A, Zaboli G, Igl W, Johansson AC, Rivas MA, Daly MJ, Schmitz G, Hicks AA, Meitinger T, Feuk L, van Duijn C, Oostra B, Pramstaller PP, Rudan I, Wright AF, Wilson JF, Campbell H, Gyllensten U. Genetic adaptation of fatty-acid metabolism: a human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids. Am J Hum Genet. 2012 May 4;90(5):809-20.

661. Amin N, Byrne E, Johnson J, Chenevix-Trench G, Walter S, Nolte IM; kConFab Investigators, Vink JM, Rawal R, Mangino M, Teumer A, Keers JC, Verwoert G, Baumeister S, Biffar R, Petersmann A, Dahmen N, Doering A, Isaacs A, Broer L, Wray NR, Montgomery GW, Levy D, Psaty BM, Gudnason V, Chakravarti A, Sulem P, Gudbjartsson DF, Kiemeney LA, Thorsteinsdottir U, Stefansson K, van Rooij FJ, Aulchenko YS, Hottenga JJ, Rivadeneira FR, Hofman A, Uitterlinden AG, Hammond CJ, Shin SY, Ikram A, Witteman JC, Janssens AC, Snieder H, Tiemeier H, Wolfenbuttel BH, Oostra BA, Heath AC, Wichmann E, Spector TD, Grabe HJ, Boomsma DI, Martin NG, van Duijn CM. Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Mol Psychiatry. 2012 Nov;17(11):1116-29.

662. Amin N, Hottenga JJ, Hansell NK, Janssens AC, de Moor MH, Madden PA, Zorkoltseva IV, Penninx BW, Terracciano A, Uda M, Tanaka T, Esko T, Realo A, Ferrucci L, Luciano M,

Davies G, Metspalu A, Abecasis GR, Deary IJ, Raikkonen K, Bierut LJ, Costa PT, Saviouk V, Zhu G, Kirichenko AV, Isaacs A, Aulchenko YS, Willemsen G, Heath AC, Pergadia ML, Medland SE, Axenovich TI, de Geus E, Montgomery GW, Wright MJ, Oostra BA, Martin NG, Boomsma DI, van Duijn CM. Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions. Eur J Hum Genet. 2012 Dec 5.

663. Amin N, Schuur M, Gusareva ES, Isaacs A, Aulchenko YS, Kirichenko AV, Zorkoltseva IV, Axenovich TI, Oostra BA, Janssens AC, van Duijn CM. A genome-wide linkage study of individuals with high scores on NEO personality traits. Mol Psychiatry. 2012 Oct;17(10):1031-41.

664. Baas DC, Ho L, Tanck MW, Fritsche LG, Merriam JE, van het Slot R, Koeleman BP, Gorgels TG, van Duijn CM, Uitterlinden AG, de Jong PT, Hofman A, ten Brink JB, Vingerling JR, Klaver CC, Dean M, Weber BH, Allikmets R, Hageman GS, Bergen AA. Multicenter cohort association study of SLC2A1 single nucleotide polymorphisms and age-related macular degeneration. Mol Vis. 2012;18:657-74.

665. Bakker PR, Al Hadithy AF, Amin N, van Duijn CM, van Os J, van Harten PN. Antipsychotic-Induced Movement Disorders in Long-Stay Psychiatric Patients and 45 Tag SNPs in 7 Candidate Genes: A Prospective Study. PLoS One. 2012;7(12):e50970.

666. Bakker PR, Bakker E, Amin N, van Duijn CM, van Os J, van Harten PN. Candidate gene-based association study of antipsychotic-induced movement disorders in long-stay psychiatric patients: a prospective study. PLoS One. 2012;7(5):e36561

667. Bos D, Ikram MA, Isaacs A, Verhaaren BF, Hofman A, van Duijn CM, Witteman JC, van der Lugt A, Vernooij MW. Genetic Loci for Coronary Calcification and Serum Lipids Relate to Aortic and Carotid Calcification. Circ Cardiovasc Genet. 2012 Dec 16.

668. Bradfield JP, Taal HR, Timpson NJ, Scherag A, Lecoeur C, Warrington NM, Hypponen E, Holst C, Valcarcel B, Thiering E, Salem RM, Schumacher FR, Cousminer DL, Sleiman PM, Zhao J, Berkowitz RI, Vimaleswaran KS, Jarick I, Pennell CE, Evans DM, St Pourcain B, Berry DJ, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, van der Valk RJ, de Jongste JC, Postma DS, Boomsma DI, Gauderman WJ, Hassanein MT, Lindgren CM, Mägi R, Boreham CA, Neville CE, Moreno LA, Elliott P, Pouta A, Hartikainen AL, Li M, Raitakari O, Lehtimäki T, Eriksson JG, Palotie A, Dallongeville J, Das S, Deloukas P, McMahon G, Ring SM, Kemp JP, Buxton JL, Blakemore AI, Bustamante M, Guxens M, Hirschhorn JN, Gillman MW, Kreiner-Møller E, Bisgaard H, Gilliland FD, Heinrich J, Wheeler E, Barroso I, O'Rahilly S, Meirhaeghe A, Sørensen TI, Power C, Palmer LJ, Hinney A, Widen E, Farooqi IS, McCarthy MI, Froguel P, Meyre D, Hebebrand J, Jarvelin MR, Jaddoe VW, Smith GD, Hakonarson H, Grant SF; Early Growth Genetics Consortium. A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet. 2012;44(5):526-31.

669. Broer L, Demerath EW, Garcia ME, Homuth G, Kaplan RC, Lunetta KL, Tanaka T, Tranah GJ, Walter S, Arnold AM, Atzmon G, Harris TB, Hoffmann W, Karasik D, Kiel DP, Kocher T, Launer LJ, Lohman KK, Rotter JI, Tiemeier H, Uitterlinden AG, Wallaschofski H, Bandinelli S, Dörr M, Ferrucci L, Franceschini N, Gudnason V, Hofman A, Liu Y, Murabito

JM, Newman AB, Oostra BA, Psaty BM, Smith AV, van Duijn CM. Association of heat shock proteins with all-cause mortality. Age (Dordr). 2012 May 4.

670. Bullock JM, Medway C, Cortina-Borja M, Turton JC, Prince JA, Ibrahim-Verbaas CA, Schuur M, Breteler MM, van Duijn CM, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Hammond N, Combarros O, Mateo I, Warden DR, Lehmann MG, Belbin O, Brown K, Wilcock GK, Heun R, Kölsch H, Smith AD, Lehmann DJ, Morgan K. Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease. Neurobiol Aging. 2012 Oct 1.

671. Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa MF, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Lambert JC, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Coassin S, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; the CARe Consortium; WTCCC2, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu F, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Meisinger C, Gieger C, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki IB, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Parsa A, Bochud M, Heid IM, Kao WH, Fox CS, Köttgen A. Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet. 2012 Dec 15;21(24):5329-5343.

672. Coppus AM, Schuur M, Vergeer J, Janssens AC, Oostra BA, Verbeek MM, van Duijn CM. Plasma β amyloid and the risk of Alzheimer's disease in Down syndrome. Neurobiol Aging. 2012 Sep;33(9):1988-94.

673. Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, Lohman K, Qi L, Kanoni S, Pankow JS, Uh HW, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, Greenwood CM, Ladouceur M, Grimsby J, Manning AK, Liu CT, Kooner J, Mooser VE, Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-Vandijk K, Oostra BA, Willems SM, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari J, Kähönen M, Pramstaller PP, Evans DM, St Pourcain B, Sattar N, Wood AR, Bandinelli S, Carlson OD, Egan JM, Böhringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio ML, Loo BM, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann HE, Deloukas P, Katsareli E, Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB; DIAGRAM+ Consortium; MAGIC Consortium; GLGC Investigators;

MuTHER Consortium, Wilson JG, Musani S, Guo X, Johnson T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, Lehtimäki T, Smith GD, Siscovick DS, Kronenberg F, van Duijn C, Loos RJ, Waterworth DM, Meigs JB, Dupuis J, Richards JB, Voight BF, Scott LJ, Steinthorsdottir V, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Hofmann OM, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Morris AD, Palmer CN, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Pedersen O, Barroso I, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Elliott P, Rybin D, Dehghan A, Hottenga JJ, Song K, Goel A, Lajunen T, Doney A, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hillman DR, Hingorani AD, Hui J, Hung J, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Martínez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Orrù M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Seedorf U, Sharp SJ, Shields B, Sigurðsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tönjes A, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Ward KL, Watkins H, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC; DIAGRAM Consortium; GIANT Consortium; Global B Pgen Consortium, Borecki IB, Meneton P, Magnusson PK, Nathan DM, Williams GH, Silander K, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Serrano-Ríos M, Lind L, Palmer LJ, Hu FB 1st, Franks PW, Ebrahim S, Marmot M, Kao WH, Pramstaller PP, Wright AF, Stumvoll M, Hamsten A; Procardis Consortium, Buchanan TA, Valle TT, Rotter JI, Penninx BW, Boomsma DI, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Peltonen

L, Mooser V, Sladek R; MAGIC investigators; GLGC Consortium, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Chasman DI, Johansen CT, Fouchier SW, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Feitosa MF, Orho-Melander M, Melander O, Li X, Li M, Cho YS, Go MJ, Kim YJ, Lee JY, Park T, Kim K, Sim X, Ong RT, Croteau-Chonka DC, Lange LA, Smith JD, Ziegler A, Zhang W, Zee RY, Whitfield JB, Thompson JR, Surakka I, Spector TD, Smit JH, Sinisalo J, Scott J, Saharinen J, Sabatti C, Rose LM, Roberts R, Rieder M, Parker AN, Pare G, O'Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, McArdle W, Masson D, Martin NG, Marroni F, Lucas G, Luben R, Lokki ML, Lettre G, Launer LJ, Lakatta EG, Laaksonen R, Kyvik KO, König IR, Khaw KT, Kaplan LM, Johansson Å, Janssens AC, Igl W, Hovingh GK, Hengstenberg C, Havulinna AS, Hastie ND, Harris TB, Haritunians T, Hall AS, Groop LC, Gonzalez E, Freimer NB, Erdmann J, Ejebe KG, Döring A, Dominiczak AF, Demissie S, Deloukas P, de Faire U, Crawford G, Chen YD, Caulfield MJ, Boekholdt SM, Assimes TL, Quertermous T, Seielstad M, Wong TY, Tai ES, Feranil AB, Kuzawa CW, Taylor HA Jr, Gabriel SB, Holm H, Gudnason V, Krauss RM, Ordovas JM, Munroe PB, Kooner JS, Tall AR, Hegele RA, Kastelein JJ, Schadt EE, Strachan DP, Reilly MP, Samani NJ, Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, Kathiresan S. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 2012 Mar;8(3):e1002607.

674. Demirkan A, Isaacs A, Ugocsai P, Liebisch G, Struchalin M, Rudan I, Wilson JF, Pramstaller PP, Gyllensten U, Campbell H, Schmitz G, Oostra BA, van Duijn CM. Plasma phosphatidylcholine and sphingomyelin concentrations are associated with depression and anxiety symptoms in a Dutch family-based lipidomics study. J Psychiatr Res. 2012 Nov 30.

675. Demirkan A, van Duijn CM, Ugocsai P, Isaacs A, Pramstaller PP, Liebisch G, Wilson JF, Johansson A, Rudan I, Aulchenko YS, Kirichenko AV, Janssens AC, Jansen RC, Gnewuch C, Domingues FS, Pattaro C, Wild SH, Jonasson I, Polasek O, Zorkoltseva IV, Hofman A, Karssen LC, Struchalin M, Floyd J, Igl W, Biloglav Z, Broer L, Pfeufer A, Pichler I, Campbell S, Zaboli G, Kolcic I, Rivadeneira F, Huffman J, Hastie ND, Uitterlinden A, Franke L, Franklin CS, Vitart V; DIAGRAM Consortium, Nelson CP, Preuss M; CARDIoGRAM Consortium, Bis JC, O'Donnell CJ, Franceschini N; CHARGE Consortium, Witteman JC, Axenovich T, Oostra BA, Meitinger T, Hicks AA, Hayward C, Wright AF, Gyllensten U, Campbell H, Schmitz G; on behalf of the EUROSPAN consortium. Genome-Wide Association Study Identifies Novel Loci Associated with Circulating PhosphoandSphingolipid Concentrations.PLoSGenet.2012Feb;8(2)

676. de Moor MH, Costa PT, Terracciano A, Krueger RF, de Geus EJ, Toshiko T, Penninx BW, Esko T, Madden PA, Derringer J, Amin N, Willemsen G, Hottenga JJ, Distel MA, Uda M, Sanna S, Spinhoven P, Hartman CA, Sullivan P, Realo A, Allik J, Heath AC, Pergadia ML, Agrawal A, Lin P, Grucza R, Nutile T, Ciullo M, Rujescu D, Giegling I, Konte B, Widen E, Cousminer DL, Eriksson JG, Palotie A, Peltonen L, Luciano M, Tenesa A, Davies G, Lopez LM, Hansell NK, Medland SE, Ferrucci L, Schlessinger D, Montgomery GW, Wright MJ, Aulchenko YS, Janssens AC, Oostra BA, Metspalu A, Abecasis GR, Deary IJ, Räikkönen K, Bierut LJ, Martin NG, van Duijn CM, Boomsma DI. Meta-analysis of genome-wide association studies for personality. Mol Psychiatry. 2012 Mar;17(3):337-49.

677. Diack AB, Ritchie D, Bishop M, Pinion V, Brandel JP, Haik S, Tagliavini F, Van Duijn C, Belay ED, Gambetti P, Schonberger LB, Piccardo P, Will RG, Manson JC. Constant transmission properties of variant Creutzfeldt-Jakob disease in 5 countries. Emerg Infect Dis. 2012 Oct;18(10):1574-9.

678. Durik M, Kavousi M, van der Pluijm I, Isaacs A, Cheng C, Verdonk K, Loot AE, Oeseburg H, Bhaggoe UM, Leijten F, van Veghel R, de Vries R, Rudez G, Brandt R, Ridwan YR, van Deel ED, de Boer M, Tempel D, Fleming I, Mitchell GF, Verwoert GC, Tarasov KV, Uitterlinden AG, Hofman A, Duckers HJ, van Duijn CM, Oostra BA, Witteman JC, Duncker DJ, Danser AH, Hoeijmakers JH, Roks AJ. Nucleotide excision DNA repair is associated with age-related vascular dysfunction. Circulation. 2012 Jul 24;126(4):468-78.

679. Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium, Bis JC, Decarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, Destefano AL, Lambert JC, Jack CR Jr, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM; the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT Jr, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 Apr 15;44(5):545-551. doi: 10.1038/ng.2237.

680. Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ, Thorleifsson G, Wilson SG, Wilson JF, Aalto V, Alen M, Aragaki AK, Aspelund T, Center JR, Dailiana Z, Duggan DJ, Garcia M, Garcia-Giralt N, Giroux S, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Khusainova R, Kim GS, Kooperberg C, Koromila T, Kruk M, Laaksonen M, Lacroix AZ, Lee SH, Leung PC, Lewis JR, Masi L, Mencej-Bedrac S, Nguyen TV, Nogues X, Patel MS, Prezelj J, Rose LM, Scollen S, Siggeirsdottir K, Smith AV, Svensson O, Trompet S, Trummer O, van Schoor NM, Woo J, Zhu K, Balcells S, Brandi ML, Buckley BM, Cheng S, Christiansen C, Cooper C, Dedoussis G, Ford I, Frost M, Goltzman D, González-Macías J, Kähönen M, Karlsson M, Khusnutdinova E, Koh JM, Kollia P, Langdahl BL, Leslie WD, Lips P, Ljunggren O, Lorenc RS, Marc J, Mellström D, Obermayer-Pietsch B, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Ridker PM, Rousseau F, Lagboom PE, Tang NL, Urreizti R, Van Hul W, Viikari J, Zarrabeitia MT, Aulchenko YS, Castano-Betancourt M, Grundberg E, Herrera L, Ingvarsson T, Johannsdottir H, Kwan T, Li R, Luben R, Medina-Gómez C, Th Palsson S, Reppe S, Rotter JI, Sigurdsson G, van Meurs JB, Verlaan D, Williams FM, Wood AR, Zhou Y, Gautvik KM, Pastinen T, Raychaudhuri S, Cauley JA, Chasman DI, Clark GR, Cummings SR, Danoy P, Dennison EM, Eastell R, Eisman JA, Gudnason V, Hofman A, Jackson RD, Jones G, Jukema JW, Khaw KT, Lehtimäki T, Liu Y, Lorentzon M, McCloskey E, Mitchell BD, Nandakumar K, Nicholson GC, Oostra BA, Peacock M, Pols HA, Prince RL, Raitakari O, Reid IR, Robbins J, Sambrook PN, Sham PC, Shuldiner AR, Tylavsky FA, van Duijn CM, Wareham NJ, Cupples LA, Econs MJ, Evans DM, Harris TB, Kung AW, Psaty BM, Reeve J, Spector TD, Streeten EA, Zillikens MC, Thorsteinsdottir U, Ohlsson C, Karasik D, Richards JB, Brown MA, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet. 2012 Apr 15;44(5):491-501.

681. Fox CS, Liu Y, White CC, Feitosa M, Smith AV, Heard-Costa N, Lohman K; GIANT Consortium; MAGIC Consortium; GLGC Consortium, Johnson AD, Foster MC, Greenawalt DM, Griffin P, Ding J, Newman AB, Tylavsky F, Miljkovic I, Kritchevsky SB, Launer L, Garcia M, Eiriksdottir G, Carr JJ, Gudnason V, Harris TB, Cupples LA, Borecki IB. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet. 2012 May;8(5):e1002695.

682. Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, Okada Y, Polasek O, Westra HJ, Wang YA, Del Greco M F, Glazer NL, Kapur K, Kema IP, Lopez LM, Schillert A, Smith AV, Winkler CA, Zgaga L; The LifeLines Cohort Study, Bandinelli S, Bergmann S, Boban M, Bochud M, Chen YD, Davies G, Dehghan A, Ding J, Doering A, Durda JP, Ferrucci L, Franco OH, Franke L, Gunjaca G, Hofman A, Hsu FC, Kolcic I, Kraja A, Kubo M, Lackner KJ, Launer L, Loehr LR, Li G, Meisinger C, Nakamura Y, Schwienbacher C, Starr JM, Takahashi A, Torlak V, Uitterlinden AG, Vitart V, Waldenberger M, Wild PS, Kirin M, Zeller T, Zemunik T, Zhang Q, Ziegler A, Blankenberg S, Boerwinkle E, Borecki IB, Campbell H, Deary IJ, Frayling TM, Gieger C, Harris TB, Hicks AA, Koenig W, O'Donnell CJ, Fox CS, Pramstaller PP, Psaty BM, Reiner AP, Rotter JI, Rudan I, Snieder H, Tanaka T, van Duijn CM, Vollenweider P, Waeber G, Wilson JF, Witteman JC, Wolffenbuttel BH, Wright AF, Wu Q, Liu Y, Jenny NS, North KE, Felix JF, Alizadeh BZ, Cupples LA, Perry JR, Morris AP. Discovery and Fine Mapping of Serum Protein Loci through Transethnic Meta-analysis. Am J Hum Genet. 2012 Oct 5;91(4):744-753.

683. Freilinger T, Anttila V, de Vries B, Malik R, Kallela M, Terwindt GM, Pozo-Rosich P, Winsvold B, Nyholt DR, van Oosterhout WP, Artto V, Todt U, Hämäläinen E, Fernández-Morales J, Louter MA, Kaunisto MA, Schoenen J, Raitakari O, Lehtimäki T, Vila-Pueyo M, Göbel H, Wichmann E, Sintas C, Uitterlinden AG, Hofman A, Rivadeneira F, Heinze A, Tronvik E, van Duijn CM, Kaprio J, Cormand B, Wessman M, Frants RR, Meitinger T, Müller-Myhsok B, Zwart JA, Färkkilä M, Macaya A, Ferrari MD, Kubisch C, Palotie A, Dichgans M, van den Maagdenberg AM; International Headache Genetics Consortium. Genome-wide association analysis identifies susceptibility loci for migraine without aura. Nat Genet. 2012 Jun 10;44(7):777-82.

684. Gasten AC, Ramdas WD, Broer L, van Koolwijk LM, Ikram MK, de Jong PT, Aulchenko YS, Wolfs RC, Hofman A, Rivadeneira F, Uitterlinden AG, Oostra BA, Lemij HG, Klaver CC, Jansonius NM, Vingerling JR, van Duijn CM.Genetic Epidemiologic Study of Candidate Genes Involved in the Optic Nerve Head Morphology.Invest Ophthalmol Vis Sci. 2012 Mar 21;53(3):1485-1491.

685. Grallert H, Dupuis J, Bis JC, Dehghan A, Barbalic M, Baumert J, Lu C, Smith NL, Uitterlinden AG, Roberts R, Khuseyinova N, Schnabel RB, Rice KM, Rivadeneira F, Hoogeveen RC, Fontes JD, Meisinger C, Keaney JF Jr, Lemaitre R, Aulchenko YS, Vasan RS, Ellis S, Hazen SL, van Duijn CM, Nelson JJ, März W, Schunkert H, McPherson RM, Stirnadel-Farrant HA, Psaty BM, Gieger C, Siscovick D, Hofman A, Illig T, Cushman M, Yamamoto JF, Rotter JI, Larson MG, Stewart AF, Boerwinkle E, Witteman JC, Tracy RP, Koenig W, Benjamin EJ, Ballantyne CM. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.Eur Heart J. 2012 Jan;33(2):238-51

686. Heun R, Kölsch H, Ibrahim-Verbaas CA, Combarros O, Aulchenko YS, Breteler M, Schuur M, van Duijn CM, Hammond N, Belbin O, Cortina-Borja M, Wilcock GK, Brown K, Barber R, Kehoe PG, Coto E, Alvarez V, Lehmann MG, Deloukas P, Mateo I, Morgan K, Warden DR, Smith AD, Lehmann DJ. Interactions between PPAR-α and inflammation-related cytokine genes on the development of Alzheimer's disease, observed by the Epistasis Project. Int J Mol Epidemiol Genet. 2012;3(1):39-47.

687. Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B, Evans DM, Charoen P, Kaakinen M, Cousminer DL, Lehtimäki T, Kreiner-Møller E, Warrington NM, Bustamante M, Feenstra B, Berry DJ, Thiering E, Pfab T, Barton SJ, Shields BM, Kerkhof M, van Leeuwen EM, Fulford AJ, Kutalik Z, Zhao JH, den Hoed M, Mahajan A, Lindi V, Goh LK, Hottenga JJ, Wu Y, Raitakari OT, Harder MN, Meirhaeghe A, Ntalla I, Salem RM, Jameson KA, Zhou K, Monies DM, Lagou V, Kirin M, Heikkinen J, Adair LS, Alkuraya FS, Al-Odaib A, Amouyel P, Andersson EA, Bennett AJ, Blakemore AI, Buxton JL, Dallongeville J, Das S, de Geus EJ, Estivill X, Flexeder C, Froguel P, Geller F, Godfrey KM, Gottrand F, Groves CJ, Hansen T, Hirschhorn JN, Hofman A, Hollegaard MV, Hougaard DM, Hyppönen E, Inskip HM, Isaacs A, Jørgensen T, Kanaka-Gantenbein C, Kemp JP, Kiess W, Kilpeläinen TO, Klopp N, Knight BA, Kuzawa CW, McMahon G, Newnham JP, Niinikoski H, Oostra BA, Pedersen L, Postma DS, Ring SM, Rivadeneira F, Robertson NR, Sebert S, Simell O, Slowinski T, Tiesler CM, Tönjes A, Vaag A, Viikari JS, Vink JM, Vissing NH, Wareham NJ, Willemsen G, Witte DR, Zhang H, Zhao J; The Meta-Analyses of Glucose- and Insulin-related traits Consortium (MAGIC); Early Growth Genetics (EGG) Consortium, Wilson JF, Stumvoll M, Prentice AM, Meyer BF, Pearson ER, Boreham CA, Cooper C, Gillman MW, Dedoussis GV, Moreno LA, Pedersen O, Saarinen M, Mohlke KL, Boomsma DI, Saw SM, Lakka TA, Körner A, Loos RJ, Ong KK, Vollenweider P, van Duijn CM, Koppelman GH, Hattersley AT, Holloway JW, Hocher B, Heinrich J, Power C, Melbye M, Guxens M, Pennell CE, Bønnelykke K, Bisgaard H, Eriksson JG, Widén E, Hakonarson H, Uitterlinden AG, Pouta A, Lawlor DA, Smith GD, Frayling TM, McCarthy MI, Grant SF, Jaddoe VW, Jarvelin MR, Timpson NJ, Prokopenko I, Freathy RM. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet. 2012 Dec 2.

688. Ibrahim-Verbaas CA, Zorkoltseva IV, Amin N, Schuur M, Coppus AM, Isaacs A, Aulchenko YS, Breteler MM, Ikram MA, Axenovich TI, Verbeek MM, van Swieten JC, Oostra BA, van Duijn CM. Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates Aβ-40 levels to presenilin 2. Hum Genet. 2012 Dec;131(12):1869-76.

689. Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Mook-Kanamori DO, Coker LH, Longstreth WT Jr, Niessen WJ, DeStefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CR Jr, Rivadeneira F, Uitterlinden AG, Knopman DS, Hartikainen AL, Pennell CE, Thiering E, Steegers EA, Hakonarson H, Heinrich J, Palmer LJ, Jarvelin MR, McCarthy MI, Grant SF, St Pourcain B, Timpson NJ, Smith GD, Sovio U; Early Growth Genetics Consortium, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Jaddoe VW, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley TH Jr, Schmidt H, Launer LJ, Breteler MM, DeCarli C; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet. 2012 Apr 15;44(5):539-44 Erratum in: Nat Genet. 2012 Jun;44(6):732.

690. Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Mook-Kanamori DO, Coker LH, Longstreth WT Jr, Niessen WJ, Destefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CR Jr, Rivadeneira F, Uitterlinden AG, Knopman DS, Hartikainen AL, Pennell CE, Thiering E, Steegers EA, Hakonarson H, Heinrich J, Palmer LJ, Jarvelin MR, McCarthy MI, Grant SF, St Pourcain B, Timpson NJ, Smith GD, Sovio U The Early Growth Genetics Egg Consortium, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Jaddoe VW, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley TH Jr, Schmidt H, Launer LJ, Breteler MM, Decarli C For The Cohorts For Heart And Aging Research In Genomic Epidemiology Charge Consortium. Erratum: Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet. 2012 May 29;44(6):732.

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692. Imamura M, Maeda S, Yamauchi T, Hara K, Yasuda K, Morizono T, Takahashi A, Horikoshi M, Nakamura M, Fujita H, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Ohshige T, Omori S, Iwata M, Hirose H, Kaku K, Ito C, Tanaka Y, Tobe K, Kashiwagi A, Kawamori R, Kasuga M, Kamatani N; Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, Nakamura Y, Kadowaki T. A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. Hum Mol Genet. 2012 Jul 1;21(13):3042-9.

693. Jaddoe VW, van Duijn CM, Franco OH, van der Heijden AJ, van Iizendoorn MH, de Jongste JC, van der Lugt A, Mackenbach JP, Moll HA, Raat H, Rivadeneira F, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, Hofman A. The Generation R Study: design and cohort update 2012.Eur J Epidemiol. 2012 Sep;27(9):739-56.

694. Jansen C, Parchi P, Capellari S, Ibrahim-Verbaas CA, Schuur M, Strammiello R, Corrado P, Bishop MT, van Gool WA, Verbeek MM, Baas F, van Saane W, Spliet WG, Jansen GH, van Duijn CM, Rozemuller AJ. Human prion diseases in the Netherlands (1998-2009): clinical, genetic and molecular aspects. PLoS One. 2012;7(4):e36333.

695. Janssens AC, Henneman L, Detmar SB, Khoury MJ, Steyerberg EW, Eijkemans MJ, Mushkudiani N, Oostra BA, van Duijn CM, Mackenbach JP. Accuracy of self-reported

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696. Janssens AC, Ioannidis JP, van Duijn CM, Little J, Khoury MJ; GRIPS Group. Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. Eur J Clin Invest. 2011 Sep;41(9):1004-9.

697. Jonsson T, Stefansson H, Ph D SS, Jonsdottir I, Jonsson PV, Snaedal J, Bjornsson S, Huttenlocher J, Levey AI, Lah JJ, Rujescu D, Hampel H, Giegling I, Andreassen OA, Engedal K, Ulstein I, Djurovic S, Ibrahim-Verbaas C, Hofman A, Ikram MA, van Duijn CM, Thorsteinsdottir U, Kong A, Stefansson K. Variant of TREM2 Associated with the Risk of Alzheimer's Disease. N Engl J Med. 2012 Nov 14.

698. Kelly MA, Rees SD, Hydrie MZ, Shera AS, Bellary S, O'Hare JP, Kumar S, Taheri S, Basit A, Barnett AH; DIAGRAM Consortium; SAT2D Consortium. Circadian gene variants and susceptibility to type 2 diabetes: a pilot study. PLoS One. 2012;7(4):e32670.

699. Kölsch H, Lehmann DJ, Ibrahim-Verbaas CA, Combarros O, van Duijn CM, Hammond N, Belbin O, Cortina-Borja M, Lehmann MG, Aulchenko YS, Schuur M, Breteler M, Wilcock GK, Brown K, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Mateo I, Maier W, Morgan K, Warden DR, Smith AD, Heun R. Interaction of insulin and PPAR-α genes in Alzheimer's disease: the Epistasis Project.J Neural Transm. 2012 Apr;119(4):473-9.

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702. Luciano M, Lopez LM, de Moor MH, Harris SE, Davies G, Nutile T, Krueger RF, Esko T, Schlessinger D, Toshiko T, Derringer JL, Realo A, Hansell NK, Pergadia ML, Pesonen AK, Sanna S, Terracciano A, Madden PA, Penninx B, Spinhoven P, Hartman CA, Oostra BA, Janssens AC, Eriksson JG, Starr JM, Cannas A, Ferrucci L, Metspalu A, Wright MJ, Heath AC, van Duijn CM, Bierut LJ, Raikkonen K, Martin NG, Ciullo M, Rujescu D, Boomsma DI, Deary IJ. Longevity candidate genes and their association with personality traits in the elderly. Am J Med Genet B Neuropsychiatr Genet. 2012 Mar;159B(2):192-200.

703. Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V, Lahti J, Lecoeur C, Liu Y, Martinez-Larrad MT, Montasser ME, Navarro P, Perry JR, Rasmussen-Torvik LJ, Salo P, Sattar N, Shungin D, Strawbridge RJ, Tanaka T, van Duijn CM, An P, de Andrade M, Andrews JS, Aspelund T, Atalay M, Aulchenko Y, Balkau B, Bandinelli S, Beckmann JS, Beilby JP, Bellis C, Bergman RN, Blangero J, Boban M, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Borecki IB, Böttcher Y, Bouchard C, Brunner E, Budimir D, Campbell H, Carlson O, Chines PS, Clarke R, Collins FS, Corbatón-Anchuelo A, Couper D, de Faire U, Dedoussis GV, Deloukas P, Dimitriou M, Egan JM, Eiriksdottir G, Erdos MR, Eriksson JG, Eury E, Ferrucci L, Ford I, Forouhi NG, Fox CS, Franzosi MG, Franks PW, Frayling TM, Froguel P, Galan P, de Geus E, Gigante B, Glazer NL, Goel A, Groop L, Gudnason V, Hallmans G, Hamsten A, Hansson O, Harris TB, Hayward C, Heath S, Hercberg S, Hicks AA, Hingorani A, Hofman A, Hui J, Hung J, Jarvelin MR, Jhun MA, Johnson PC, Jukema JW, Jula A, Kao WH, Kaprio J, Kardia SL, Keinanen-Kiukaanniemi S, Kivimaki M, Kolcic I, Kovacs P, Kumari M, Kuusisto J, Kyvik KO, Laakso M, Lakka T, Lannfelt L, Lathrop GM, Launer LJ, Leander K, Li G, Lind L, Lindstrom J, Lobbens S, Loos RJ, Luan J, Lyssenko V, Mägi R, Magnusson PK, Marmot M, Meneton P, Mohlke KL, Mooser V, Morken MA, Miljkovic I, Narisu N, O'Connell J, Ong KK, Oostra BA, Palmer LJ, Palotie A, Pankow JS, Peden JF, Pedersen NL, Pehlic M, Peltonen L, Penninx B, Pericic M, Perola M, Perusse L, Peyser PA, Polasek O, Pramstaller PP, Province MA, Räikkönen K, Rauramaa R, Rehnberg E, Rice K, Rotter JI, Rudan I, Ruokonen A, Saaristo T, Sabater-Lleal M, Salomaa V, Savage DB, Saxena R, Schwarz P, Seedorf U, Sennblad B, Serrano-Rios M, Shuldiner AR, Sijbrands EJ, Siscovick DS, Smit JH, Small KS, Smith NL, Smith AV, Stančáková A, Stirrups K, Stumvoll M, Sun YV, Swift AJ, Tönjes A, Tuomilehto J, Trompet S, Uitterlinden AG, Uusitupa M, Vikström M, Vitart V, Vohl MC, Voight BF, Vollenweider P, Waeber G, Waterworth DM, Watkins H, Wheeler E, Widen E, Wild SH, Willems SM, Willemsen G, Wilson JF, Witteman JC, Wright AF, Yaghootkar H, Zelenika D, Zemunik T, Zgaga L; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium; The Multiple Tissue Human Expression Resource (MUTHER) Consortium, Wareham NJ, McCarthy MI, Barroso I, Watanabe RM, Florez JC, Dupuis J, Meigs JB, Langenberg C. A genome-wide

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704. Marquez M, Huyvaert M, Perry JR, Pearson RD, Falchi M, Morris AP, Vivequin S, Lobbens S, Yengo L, Gaget S, Pattou F, Poulain-Godefroy O, Charpentier G, Carlsson LM, Jacobson P, Sjöström L, Lantieri O, Heude B, Walley A, Balkau B, Marre M, Froguel P, Cauchi S; DIAGRAM Consortium. Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk.Diabetes. 2012 Feb;61(2):524-30.

705. McQuillan R, Eklund N, Pirastu N, Kuningas M, McEvoy BP, Esko T, Corre T, Davies G, Kaakinen M, Lyytikäinen LP, Kristiansson K, Havulinna AS, Gögele M, Vitart V, Tenesa A, Aulchenko Y, Hayward C, Johansson A, Boban M, Ulivi S, Robino A, Boraska V, Igl W, Wild SH, Zgaga L, Amin N, Theodoratou E, Polašek O, Girotto G, Lopez LM, Sala C, Lahti J, Laatikainen T, Prokopenko I, Kals M, Viikari J, Yang J, Pouta A, Estrada K, Hofman A, Freimer N, Martin NG, Kähönen M, Milani L, Heliövaara M, Vartiainen E, Räikkönen K, Masciullo C, Starr JM, Hicks AA, Esposito L, Kolčić I, Farrington SM, Oostra B, Zemunik T, Campbell H, Kirin M, Pehlic M, Faletra F, Porteous D, Pistis G, Widén E, Salomaa V, Koskinen S, Fischer K, Lehtimäki T, Heath A, McCarthy MI, Rivadeneira F, Montgomery GW, Tiemeier H, Hartikainen AL, Madden PA, d'Adamo P, Hastie ND, Gyllensten U, Wright AF, van Duijn CM, Dunlop M, Rudan I, Gasparini P, Pramstaller PP, Deary IJ, Toniolo D, Eriksson JG, Jula A, Raitakari OT, Metspalu A, Perola M, Järvelin MR, Uitterlinden A, Visscher PM, Wilson JF; on behalf of the ROHgen Consortium. Evidence of Inbreeding Depression on Human Height. PLoS Genet. 2012 Jul;8(7):e1002655.

706. Medici M, Rivadeneira F, van der Deure WM, Hofman A, van Meurs JB, Styrkársdottir U, van Duijn CM, Spector T, Kiel DP; GEFOS Consortium, Uitterlinden AG, Visser TJ, Peeters RP. A large-scale population-based analysis of common genetic variation in the thyroid hormone receptor alpha locus and bone. Thyroid. 2012 Feb;22(2):223-4.

707. Mitchell GF, Verwoert GC, Tarasov KV, Isaacs A, Smith AV, Yasmin, Rietzschel ER, Tanaka T, Liu Y, Parsa A, Najjar SS, O'Shaughnessy KM, Sigurdsson S, De Buyzere ML, Larson MG, Sie MP, Andrews JS, Post WS, Mattace-Raso FU, McEniery CM, Eiriksdottir G, Segers P, Vasan RS, van Rijn MJ, Howard TD, McArdle PF, Dehghan A, Jewell ES, Newhouse SJ, Bekaert S, Hamburg NM, Newman AB, Hofman A, Scuteri A, De Bacquer D, Arfan Ikram M, Psaty BM, Fuchsberger C, Olden M, Wain LV, Elliott P, Smith NL, Felix JF, Erdmann J, Vita JA, Sutton-Tyrrell K, Sijbrands EJ, Sanna S, Launer LJ, De Meyer T, Johnson AD, Schut AF, Herrington DM, Rivadeneira F, Uda M, Wilkinson IB, Aspelund T, Gillebert TC, Van Bortel L, Benjamin EJ, Oostra BA, Ding J, Gibson Q, Uitterlinden AG, Abecasis GR, Cockcroft JR, Gudnason V, De Backer GG, Ferrucci L, Harris TB, Shuldiner AR, van Duijn CM, Levy D, Lakatta EG, Witteman JC. Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium.Circ Cardiovasc Genet. 2012 Feb 1;5(1):81-90.

708. Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A, Prokopenko I, Kang HM, Dina C, Esko T, Fraser RM, Kanoni S, Kumar A, Lagou V, Langenberg C, Luan J, Lindgren CM, Müller-Nurasyid M, Pechlivanis S, Rayner NW, Scott LJ, Wiltshire S, Yengo L, Kinnunen L, Rossin EJ, Raychaudhuri S, Johnson AD, Dimas AS, Loos RJ, Vedantam S, Chen H, Florez JC, Fox C, Liu CT, Rybin D, Couper DJ, Kao WH, Li M, Cornelis MC, Kraft P, Sun Q, van Dam RM,

Stringham HM, Chines PS, Fischer K, Fontanillas P, Holmen OL, Hunt SE, Jackson AU, Kong A, Lawrence R, Meyer J, Perry JR, Platou CG, Potter S, Rehnberg E, Robertson N, Sivapalaratnam S, Stančáková A, Stirrups K, Thorleifsson G, Tikkanen E, Wood AR, Almgren P, Atalay M, Benediktsson R, Bonnycastle LL, Burtt N, Carey J, Charpentier G, Crenshaw AT, Doney AS, Dorkhan M, Edkins S, Emilsson V, Eury E, Forsen T, Gertow K, Gigante B, Grant GB, Groves CJ, Guiducci C, Herder C, Hreidarsson AB, Hui J, James A, Jonsson A, Rathmann W, Klopp N, Kravic J, Krjutškov K, Langford C, Leander K, Lindholm E, Lobbens S, Männistö S, Mirza G, Mühleisen TW, Musk B, Parkin M, Rallidis L, Saramies J, Sennblad B, Shah S, Sigurðsson G, Silveira A, Steinbach G, Thorand B, Trakalo J, Veglia F, Wennauer R, Winckler W, Zabaneh D, Campbell H, van Duijn C, Uitterlinden AG, Hofman A, Sijbrands E, Abecasis GR, Owen KR, Zeggini E, Trip MD, Forouhi NG, Syvänen AC, Eriksson JG, Peltonen L, Nöthen MM, Balkau B, Palmer CN, Lyssenko V, Tuomi T, Isomaa B, Hunter DJ, Qi L; Wellcome Trust Case Control Consortium; Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) Investigators; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; Asian Genetic Epidemiology Network–Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium, Shuldiner AR, Roden M, Barroso I, Wilsgaard T, Beilby J, Hovingh K, Price JF, Wilson JF, Rauramaa R, Lakka TA, Lind L, Dedoussis G, Njølstad I, Pedersen NL, Khaw KT, Wareham NJ, Keinanen-Kiukaanniemi SM, Saaristo TE, Korpi-Hyövälti E, Saltevo J, Laakso M, Kuusisto J, Metspalu A, Collins FS, Mohlke KL, Bergman RN, Tuomilehto J, Boehm BO, Gieger C, Hveem K, Cauchi S, Froguel P, Baldassarre D, Tremoli E, Humphries SE, Saleheen D, Danesh J, Ingelsson E, Ripatti S, Salomaa V, Erbel R, Jöckel KH, Moebus S, Peters A, Illig T, de Faire U, Hamsten A, Morris AD, Donnelly PJ, Frayling TM, Hattersley AT, Boerwinkle E, Melander O, Kathiresan S, Nilsson PM, Deloukas P, Thorsteinsdottir U, Groop LC, Stefansson K, Hu F, Pankow JS, Dupuis J, Meigs JB, Altshuler D, Boehnke M, McCarthy MI; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012 Sep;44(9):981-90.

709. Murabito JM, White CC, Kavousi M, Sun YV, Feitosa MF, Nambi V, Lamina C, Schillert A, Coassin S, Bis JC, Broer L, Crawford DC, Franceschini N, Frikke-Schmidt R, Haun M, Holewijn S, Huffman JE, Hwang SJ, Kiechl S, Kollerits B, Montasser ME, Nolte IM, Rudock ME, Senft A, Teumer A, van der Harst P, Vitart V, Waite LL, Wood AR, Wassel CL, Absher DM, Allison MA, Amin N, Arnold A, Asselbergs FW, Aulchenko Y, Bandinelli S, Barbalic M, Boban M, Brown-Gentry K, Couper DJ, Criqui MH, Dehghan A, den Heijer M, Dieplinger B, Ding J, Dörr M, Espinola-Klein C, Felix SB, Ferrucci L, Folsom AR, Fraedrich G, Gibson Q, Goodloe R, Gunjaca G, Haltmayer M, Heiss G, Hofman A, Kieback A, Kiemeney LA, Kolcic I, Kullo IJ, Kritchevsky SB, Lackner KJ, Li X, Lieb W, Lohman K, Meisinger C, Melzer D, Mohler ER 3rd, Mudnic I, Mueller T, Navis G, Oberhollenzer F, Olin JW, O'Connell J, O'Donnell CJ, Palmas W, Penninx BW, Petersmann A, Polasek O, Psaty BM, Rantner B, Rice K, Rivadeneira F, Rotter JI, Seldenrijk A, Stadler M, Summerer M, Tanaka T, Tybjaerg-Hansen A, Uitterlinden AG, van Gilst WH, Vermeulen SH, Wild SH, Wild PS, Willeit J, Zeller T, Zemunik T, Zgaga L, Assimes TL, Blankenberg S, Boerwinkle E, Campbell H, Cooke JP, de Graaf J, Herrington D, Kardia SL, Mitchell BD, Murray A, Münzel T, Newman AB, Oostra BA, Rudan I, Shuldiner AR, Snieder H, van Duijn CM, Völker U, Wright AF, Wichmann HE, Wilson JF, Witteman JC, Liu Y, Hayward C, Borecki IB, Ziegler A, North KE, Cupples LA, Kronenberg F. Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet. 2012 Feb 1;5(1):100-12.

710. Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S, Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo YY, Kim YJ, Lee JY, Han BG, Kang D, Chen CH, Tsai FJ, Chang LC, Fann SJ, Mei H, Rao DC, Hixson JE, Chen S, Katsuya T, Isono M, Ogihara T, Chambers JC, Zhang W, Kooner JS; KidneyGen Consortium; CKDGen Consortium, Albrecht E; GUGC consortium, Yamamoto K, Kubo M, Nakamura Y, Kamatani N, Kato N, He J, Chen YT, Cho YS, Tai ES, Tanaka T. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet. 2012 Jul 15;44(8):904-9.

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713. Paternoster L, Standl M, Chen CM, Ramasamy A, Bønnelykke K, Duijts L, Ferreira MA, Alves AC, Thyssen JP, Albrecht E, Baurecht H, Feenstra B, Sleiman PM, Hysi P, Warrington NM, Curjuric I, Myhre R, Curtin JA, Groen-Blokhuis MM, Kerkhof M, Sääf A, Franke A, Ellinghaus D, Fölster-Holst R, Dermitzakis E, Montgomery SB, Prokisch H, Heim K, Hartikainen AL, Pouta A, Pekkanen J, Blakemore AI, Buxton JL, Kaakinen M, Duffy DL, Madden PA, Heath AC, Montgomery GW, Thompson PJ, Matheson MC, Le Souëf P; Australian Asthma Genetics Consortium (AAGC), St Pourcain B, Smith GD, Henderson J, Kemp JP, Timpson NJ, Deloukas P, Ring SM, Wichmann HE, Müller-Nurasyid M, Novak N, Klopp N, Rodríguez E, McArdle W, Linneberg A, Menné T, Nohr EA, Hofman A, Uitterlinden AG, van Duijn CM, Rivadeneira F, de Jongste JC, van der Valk RJ, Wjst M, Jogi R, Geller F, Boyd HA, Murray JC, Kim C, Mentch F, March M, Mangino M, Spector TD, Bataille V, Pennell CE, Holt PG, Sly P, Tiesler CM, Thiering E, Illig T, Imboden M, Nystad W, Simpson A, Hottenga JJ, Postma D, Koppelman GH, Smit HA, Söderhäll C, Chawes B, Kreiner-Møller E, Bisgaard H, Melén E, Boomsma DI, Custovic A, Jacobsson B, Probst-Hensch NM, Palmer LJ, Glass D, Hakonarson H, Melbye M, Jarvis DL, Jaddoe VW, Gieger C; Genetics of Overweight Young Adults (GOYA) Consortium, Strachan DP, Martin NG, Jarvelin MR, Heinrich J, Evans DM, Weidinger S; EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium. Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nat Genet. 2011 Dec 25;44(2):187-92.

714. Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, Fuchsberger C, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa M, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Chouraki V, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; CARe Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2), Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu FB, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Koenig W, Illig T, Döring A, Wichmann HE, Kolcic I, Zemunik T, Boban M, Minelli C,

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715. Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, Balkau B, Benediktsson R, Bergman RN, Boerwinkle E, Bonnycastle L, Burtt NP, Campbell H, Charpentier G, Collins FS, Gieger C, Green T, Hadjadj S, Hattersley AT, Herder C, Hofman A, Johnson AD, Kottgen A, Kraft P, Labrune Y, Langenberg C, Manning AK, Mohlke KL, Morris AP, Oostra B, Pankow J, Petersen AK, Pramstaller PP, Prokopenko I, Rathmann W, Rayner W, Roden M, Rudan I, Rybin D, Scott LJ, Sigurdsson G, Sladek R, Thorleifsson G, Thorsteinsdottir U, Tuomilehto J, Uitterlinden AG, Vivequin S, Weedon MN, Wright AF; MAGIC; DIAGRAM Consortium; GIANT Consortium, Hu FB, Illig T, Kao L, Meigs JB, Wilson JF, Stefansson K, van Duijn C, Altschuler D, Morris AD, Boehnke M, McCarthy MI, Froguel P, Palmer CN, Wareham NJ, Groop L, Frayling TM, Cauchi S. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet. 2012 May;8(5):e1002741

716. Peters MJ, Broer L, Willemen HL, Eiriksdottir G, Hocking LJ, Holliday KL, Horan MA, Meulenbelt I, Neogi T, Popham M, Schmidt CO, Soni A, Valdes AM, Amin N, Dennison EM, Eijkelkamp N, Harris TB, Hart DJ, Hofman A, Huygen FJ, Jameson KA, Jones GT, Launer LJ, Kerkhof HJ, de Kruijf M, McBeth J, Kloppenburg M, Ollier WE, Oostra B, Payton A, Rivadeneira F, Smith BH, Smith AV, Stolk L, Teumer A, Thomson W, Uitterlinden AG, Wang K, van Wingerden SH, Arden NK, Cooper C, Felson D, Gudnason V, Macfarlane GJ, Pendleton N, Slagboom PE, Spector TD, Völzke H, Kavelaars A, van Duijn CM, Williams FM, van Meurs JB. Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region. Ann Rheum Dis. 2012 Sep 21.

717. Rodenburg EM, Eijgelsheim M, Geleijnse JM, Amin N, van Duijn CM, Hofman A, Uitterlinden AG, Stricker BH, Visser LE.. CYP1A2 and coffee intake and the modifying effect of sex, age, and smoking. Am J Clin Nutr. 2012 Jul;96(1):182-7.

718. Sanchez-Juan P, Bishop MT, Aulchenko YS, Brandel JP, Rivadeneira F, Struchalin M, Lambert JC, Amouyel P, Combarros O, Sainz J, Carracedo A, Uitterlinden AG, Hofman A, Zerr I, Kretzschmar HA, Laplanche JL, Knight RS, Will RG, van Duijn CM. Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk. Neurobiol Aging. 2012 Jul;33(7):1487.e21-8.

719. Schrijvers EM, Schürmann B, Koudstaal PJ, van den Bussche H, Van Duijn CM, Hentschel F, Heun R, Hofman A, Jessen F, Kölsch H, Kornhuber J, Peters O, Rivadeneira F, Rüther E, Uitterlinden AG, Riedel-Heller S, Dichgans M, Wiltfang J, Maier W, Breteler MM, Ikram MA. Genome-wide association study of vascular dementia. Stroke. 2012 Feb;43(2):315-9.

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721. Singaraja RR, Sivapalaratnam S, Hovingh K, Dubé MP, Castro-Perez J, Collins HL, Adelman SJ, Riwanto M, Manz J, Hubbard B, Tietjen I, Wong K, Mitnaul LJ, van Heek M, Lin L, Roddy TA, McEwen J, Dallinge-Thie G, van Vark-van der Zee L, Verwoert G, Winther M, van Duijn C, Hofman A, Trip MD, Marais AD, Asztalos B, Landmesser U, Sijbrands E, Kastelein JJ, Hayden MR. The Impact of Partial and Complete Loss of Function Mutations in Endothelial Lipase on HDL Levels and Functionality in Humans.Circ Cardiovasc Genet. 2012 Dec 14.

722. Sobrin L, Ripke S, Yu Y, Fagerness J, Bhangale TR, Tan PL, Souied EH, Buitendijk GH, Merriam JE, Richardson AJ, Raychaudhuri S, Reynolds R, Chin KA, Lee AY, Leveziel N, Zack DJ, Campochiaro P, Smith RT, Barile GR, Hogg RE, Chakravarthy U, Behrens TW, Uitterlinden AG, van Duijn CM, Vingerling JR, Brantley MA Jr, Baird PN, Klaver CC, Allikmets R, Katsanis N, Graham RR, Ioannidis JP, Daly MJ, Seddon JM. Heritability and

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726. Stoeck K, Sanchez-Juan P, Gawinecka J, Green A, Ladogana A, Pocchiari M, Sanchez-Valle R, Mitrova E, Sklaviadis T, Kulczycki J, Slivarichova D, Saiz A, Calero M, Knight R, Aguzzi A, Laplanche JL, Peoc'h K, Schelzke G, Karch A, van Duijn CM, Zerr I. Cerebrospinal fluid

biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias: a longitudinal multicentre study over 10 years. Brain. 2012 Oct;135(Pt 10):3051-61.

727. Stolk L, Perry JR, Chasman DI, He C, Mangino M, Sulem P, Barbalic M, Broer L, Byrne EM, Ernst F, Esko T, Franceschini N, Gudbjartsson DF, Hottenga JJ, Kraft P, McArdle PF, Porcu E, Shin SY, Smith AV, van Wingerden S, Zhai G, Zhuang WV, Albrecht E, Alizadeh BZ, Aspelund T, Bandinelli S, Lauc LB, Beckmann JS, Boban M, Boerwinkle E, Broekmans FJ, Burri A, Campbell H, Chanock SJ, Chen C, Cornelis MC, Corre T, Coviello AD, d'Adamo P, Davies G, de Faire U, de Geus EJ, Deary IJ, Dedoussis GV, Deloukas P, Ebrahim S, Eiriksdottir G, Emilsson V, Eriksson JG, Fauser BC, Ferreli L, Ferrucci L, Fischer K, Folsom AR, Garcia ME, Gasparini P, Gieger C, Glazer N, Grobbee DE, Hall P, Haller T, Hankinson SE, Hass M, Hayward C, Heath AC, Hofman A, Ingelsson E, Janssens AC, Johnson AD, Karasik D, Kardia SL, Keyzer J, Kiel DP, Kolcic I, Kutalik Z, Lahti J, Lai S, Laisk T, Laven JS, Lawlor DA, Liu J, Lopez LM, Louwers YV, Magnusson PK, Marongiu M, Martin NG, Klaric IM, Masciullo C, McKnight B, Medland SE, Melzer D, Mooser V, Navarro P, Newman AB, Nyholt DR, Onland-Moret NC, Palotie A, Paré G, Parker AN, Pedersen NL, Peeters PH, Pistis G, Plump AS, Polasek O, Pop VJ, Psaty BM, Räikkönen K, Rehnberg E, Rotter JI, Rudan I, Sala C, Salumets A, Scuteri A, Singleton A, Smith JA, Snieder H, Soranzo N, Stacey SN, Starr JM, Stathopoulou MG, Stirrups K, Stolk RP, Styrkarsdottir U, Sun YV, Tenesa A, Thorand B, Toniolo D, Tryggvadottir L, Tsui K, Ulivi S, van Dam RM, van der Schouw YT, van Gils CH, van Nierop P, Vink JM, Visscher PM, Voorhuis M, Waeber G, Wallaschofski H, Wichmann HE, Widen E, Wijnands-van Gent CJ, Willemsen G, Wilson JF, Wolffenbuttel BH, Wright AF, Yerges-Armstrong LM, Zemunik T, Zgaga L, Zillikens MC, Zygmunt M, Study TL, Arnold AM, Boomsma DI, Buring JE, Crisponi L, Demerath EW, Gudnason V, Harris TB, Hu FB, Hunter DJ, Launer LJ, Metspalu A, Montgomery GW, Oostra BA, Ridker PM, Sanna S, Schlessinger D, Spector TD, Stefansson K, Streeten EA, Thorsteinsdottir U, Uda M, Uitterlinden AG, van Duijn CM, Völzke H, Murray A, Murabito JM, Visser JA, Lunetta KL. Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet. 2012 Jan 22;44(3):260-8.

728. Struchalin MV, Amin N, Eilers PH, van Duijn CM, Aulchenko YS. An R package "VariABEL" for genome-wide searching of potentially interacting loci by testing genotypic variance heterogeneity. BMC Genet. 2012Jan24.

729. Svishcheva GR, Axenovich TI, Belonogova NM, van Duijn CM, Aulchenko YS. Rapid variance components-based method for whole-genome association analysis. Nat Genet. 2012 Oct;44(10):1166-70.

730. Taal HR, St Pourcain B, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, Kaakinen M, Kreiner-Møller E, Bradfield JP, Freathy RM, Geller F, Guxens M, Cousminer DL, Kerkhof M, Timpson NJ, Ikram MA, Beilin LJ, Bønnelykke K, Buxton JL, Charoen P, Chawes BL, Eriksson J, Evans DM, Hofman A, Kemp JP, Kim CE, Klopp N, Lahti J, Lye SJ, McMahon G, Mentch FD, Müller-Nurasyid M, O'Reilly PF, Prokopenko I, Rivadeneira F, Steegers EA, Sunyer J, Tiesler C, Yaghootkar H; The Cohorts for Heart and Aging Research in Genetic Epidemiology (CHARGE) Consortium, Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Coker LH, Longstreth WT Jr, Niessen WJ, Destefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CR Jr, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley TH Jr, Schmidt H, Launer LJ, Breteler MM, Decarli C, Breteler MM,

Debette S, Fornage M, Gudnason V, Launer LJ, van der Lugt A, Mosley TH Jr, Seshadri S, Smith AV, Vernooij MW; Early Genetics & Lifecourse Epidemiology (EAGLE) Consortium, Ang W, van Beijsterveldt T, Bergen N, Benke K, Berry D, Bradfield JP, Charoen P, Coin L, Cousminer DL, Das S, Elliott P, Evans DM, Frayling T, Freathy RM, Gaillard R, Groen-Blokhuis M, Guxens M, Hadley D, Hottenga JJ, Huikari V, Hypponen E, Kaakinen M, Kowgier M, Lawlor DA, Lewin A, Lindgren C, Marsh J, Middeldorp C, Millwood I, Mook-Kanamori DO, Nivard M, O'Reilly PF, Palmer LJ, Prokopenko I, Rodriguez A, Sebert S, Sovio U, St Pourcain B, Standl M, Strachan DP, Sunyer J, Taal HR, Thiering E, Tiesler C, Uitterlinden AG, Valcárcel B, Warrington NM, White S, Willemsen G, Yaghootkar H, Boomsma DI, Estivill X, Grant SF, Hakonarson H, Hattersley AT, Heinrich J, Jaddoe VW, Jarvelin MR, McCarthy MI, Pennell CE, Power C, Timpson NJ, Widen E, Blakemore AI, Chiavacci RM, Feenstra B, Fernandez-Banet J, Grant SF, Hartikainen AL, van der Heijden AJ, Iñiguez C, Lathrop M, McArdle WL, Mølgaard A, Newnham JP, Palmer LJ, Palotie A, Pouta A, Ring SM, Sovio U, Standl M, Uitterlinden AG, Wichmann HE, Vissing NH, Decarli C, van Duijn CM, McCarthy MI, Koppelman GH, Estivill X, Hattersley AT, Melbye M, Bisgaard H, Pennell CE, Widen E, Hakonarson H, Smith GD, Heinrich J, Jarvelin MR, Jaddoe VW; Early Growth Genetics (EGG) Consortium, Adair LS, Ang W, Atalay M, van Beijsterveldt T, Bergen N, Benke K, Berry D, Bradfield JP, Charoen P, Coin L, Cousminer DL, Das S, Davis OS, Elliott P, Evans DM, Feenstra B, Flexeder C, Frayling T, Freathy RM, Gaillard R, Geller F, Groen-Blokhuis M, Goh LK, Guxens M, Haworth CM, Hadley D, Hedebrand J, Hinney A, Hirschhorn JN, Holloway JW, Holst C, Hottenga JJ, Horikoshi M, Huikari V, Hypponen E, Iñiguez C, Kaakinen M, Kilpeläinen TO, Kirin M, Kowgier M, Lakka HM, Lange LA, Lawlor DA, Lehtimäki T, Lewin A, Lindgren C, Lindi V, Maggi R, Marsh J, Middeldorp C, Millwood I, Mook-Kanamori DO, Murray JC, Nivard M, Nohr EA, Ntalla I, Oken E, O'Reilly PF, Palmer LJ, Panoutsopoulou K, Pararajasingham J, Prokopenko I, Rodriguez A, Salem RM, Sebert S, Siitonen N, Sovio U, St Pourcain B, Strachan DP, Sunyer J, Taal HR, Teo YY, Thiering E, Tiesler C, Uitterlinden AG, Valcárcel B, Warrington NM, White S, Willemsen G, Yaghootkar H, Zeggini E, Boomsma DI, Cooper C, Estivill X, Gillman M, Grant SF, Hakonarson H, Hattersley AT, Heinrich J, Hocher B, Jaddoe VW, Jarvelin MR, Lakka TA, McCarthy MI, Melbye M, Mohlke KL, Dedoussis GV, Ong KK, Pearson ER, Pennell CE, Price TS, Power C, Raitakari OT, Saw SM, Scherag A, Simell O, Sørensen TI, Timpson NJ, Widen E, Wilson JF. Common variants at 12q15 and 12q24 are associated with infant head circumference.Nat Genet. 2012 Apr 15;44(5):532-538.

731. Taal HR, Verwoert GC, Demirkan A, Janssens AC, Rice K, Ehret G, Smith AV, Verhaaren BF, Witteman JC, Hofman A, Vernooij MW, Uitterlinden AG, Rivadeneira F, Ikram MA, Levy D, van der Heijden AJ; Cohort for Heart and Aging Research in Genome Epidemiology and Early Genetics and Lifecourse Epidemiology consortia, Jaddoe VW, van Duijn CM. Genome-wide profiling of blood pressure in adults and children. Hypertension. 2012 Feb;59(2):241-7.

732. van den Berg L, Henneman P, Willems van Dijk K, Delemarre-van de Waal HA, Oostra BA, van Duijn CM, Janssens AC. Heritability of dietary food intake patterns. Acta Diabetol. 2012 Mar 15.

733. van Koolwijk LM, Ramdas WD, Ikram MK, Jansonius NM, Pasutto F, Hysi PG, Macgregor S, Janssen SF, Hewitt AW, Viswanathan AC, ten Brink JB, Hosseini SM, Amin N, Despriet DD, Willemse-Assink JJ, Kramer R, Rivadeneira F, Struchalin M, Aulchenko YS, Weisschuh N, Zenkel M, Mardin CY, Gramer E, Welge-Lüssen U, Montgomery GW, Carbonaro F, Young TL; DCCT/EDIC Research Group, Bellenguez C, McGuffin P, Foster PJ, Topouzis F,

Mitchell P, Wang JJ, Wong TY, Czudowska MA, Hofman A, Uitterlinden AG, Wolfs RC, de Jong PT, Oostra BA, Paterson AD; Wellcome Trust Case Control Consortium 2, Mackey DA, Bergen AA, Reis A, Hammond CJ, Vingerling JR, Lemij HG, Klaver CC, van Duijn CM. Common genetic determinants of intraocular pressure and primary open-angle glaucoma. PLoS Genet. 2012 May;8(5):e1002611.

734. Verhaaren BF, Vernooij MW, Koudstaal PJ, Uitterlinden AG, Duijn CM, Hofman A, Breteler MM, Ikram MA. Alzheimer's Disease Genes and Cognition in the Nondemented General Population. Biol Psychiatry. 2012 May 14.

735. Verhoeven VJ, Hysi PG, Saw SM, Vitart V, Mirshahi A, Guggenheim JA, Cotch MF, Yamashiro K, Baird PN, Mackey DA, Wojciechowski R, Ikram MK, Hewitt AW, Duggal P, Janmahasatian S, Khor CC, Fan Q, Zhou X, Young TL, Tai ES, Goh LK, Li YJ, Aung T, Vithana E, Teo YY, Tay W, Sim X, Rudan I, Hayward C, Wright AF, Polasek O, Campbell H, Wilson JF, Fleck BW, Nakata I, Yoshimura N, Yamada R, Matsuda F, Ohno-Matsui K, Nag A, McMahon G, Pourcain BS, Lu Y, Rahi JS, Cumberland PM, Bhattacharya S, Simpson CL, Atwood LD, Li X, Raffel LJ, Murgia F, Portas L, Despriet DD, van Koolwijk LM, Wolfram C, Lackner KJ, Tönjes A, Mägi R, Lehtimäki T, Kähönen M, Esko T, Metspalu A, Rantanen T, Pärssinen O, Klein BE, Meitinger T, Spector TD, Oostra BA, Smith AV, de Jong PT, Hofman A, Amin N, Karssen LC, Rivadeneira F, Vingerling JR, Eiríksdóttir G, Gudnason V, Döring A, Bettecken T, Uitterlinden AG, Williams C, Zeller T, Castagné R, Oexle K, van Duijn CM, Iyengar SK, Mitchell P, Wang JJ, Höhn R, Pfeiffer N, Bailey-Wilson JE, Stambolian D, Wong TY, Hammond CJ, Klaver CC. Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. Hum Genet. 2012 Sep;131(9):1467-80.

736. Yang J, Loos RJ, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM, Thorleifsson G, Steinthorsdottir V, Mägi R, Waite L, Smith AV, Yerges-Armstrong LM, Monda KL, Hadley D, Mahajan A, Li G, Kapur K, Vitart V, Huffman JE, Wang SR, Palmer C, Esko T, Fischer K, Zhao JH, Demirkan A, Isaacs A, Feitosa MF, Luan J, Heard-Costa NL, White C, Jackson AU, Preuss M, Ziegler A, Eriksson J, Kutalik Z, Frau F, Nolte IM, Van Vliet-Ostaptchouk JV, Hottenga JJ, Jacobs KB, Verweij N, Goel A, Medina-Gomez C, Estrada K, Bragg-Gresham JL, Sanna S, Sidore C, Tyrer J, Teumer A, Prokopenko I, Mangino M, Lindgren CM, Assimes TL, Shuldiner AR, Hui J, Beilby JP, McArdle WL, Hall P, Haritunians T, Zgaga L, Kolcic I, Polasek O, Zemunik T, Oostra BA, Junttila MJ, Grönberg H, Schreiber S, Peters A, Hicks AA, Stephens J, Foad NS, Laitinen J, Pouta A, Kaakinen M, Willemsen G, Vink JM, Wild SH, Navis G, Asselbergs FW, Homuth G, John U, Iribarren C, Harris T, Launer L, Gudnason V, O'Connell JR, Boerwinkle E, Cadby G, Palmer LJ, James AL, Musk AW, Ingelsson E, Psaty BM, Beckmann JS, Waeber G, Vollenweider P, Hayward C, Wright AF, Rudan I, Groop LC, Metspalu A, Tee Khaw K, van Duijn CM, Borecki IB, Province MA, Wareham NJ, Tardif JC, Huikuri HV, Cupples LA, Atwood LD, Fox CS, Boehnke M, Collins FS, Mohlke KL, Erdmann J, Schunkert H, Hengstenberg C, Stark K, Lorentzon M, Ohlsson C, Cusi D, Staessen JA, Van der Klauw MM, Pramstaller PP, Kathiresan S, Jolley JD, Ripatti S, Jarvelin MR, de Geus EJ, Boomsma DI, Penninx B, Wilson JF, Campbell H, Chanock SJ, van der Harst P, Hamsten A, Watkins H, Hofman A, Witteman JC, Zillikens MC, Uitterlinden AG, Rivadeneira F, Zillikens MC, Kiemeney LA, Vermeulen SH, Abecasis GR, Schlessinger D, Schipf S, Stumvoll M, Tönjes A, Spector TD, North KE, Lettre G, McCarthy MI, Berndt SI, Heath AC, Madden PA, Nyholt DR, Montgomery GW, Martin NG, McKnight B, Strachan DP, Hill WG, Snieder H, Ridker PM, Thorsteinsdottir U, Stefansson K, Frayling TM, Hirschhorn JN, Goddard ME, Visscher PM.

FTO genotype is associated with phenotypic variability of body mass index. Nature. 2012 Oct 11;490(7419):267-72.

737. Zaboli G, Ameur A, Igl W, Johansson Å, Hayward C, Vitart V, Campbell S, Zgaga L, Polasek O, Schmitz G, van Duijn C, Oostra B, Pramstaller P, Hicks A, Meitinger T, Rudan I, Wright A, Wilson JF, Campbell H, Gyllensten U; EUROSPAN Consortium. Sequencing of high-complexity DNA pools for identification of nucleotide and structural variants in regions associated with complex traits. Eur J Hum Genet. 2012 Jan;20(1):77-83.

738. Zerr I, Kallenberg K, Summers DM, Romero C, Taratuto A, Heinemann U, Breithaupt M, Varges D, Meissner B, Ladogana A, Schuur M, Haik S, Collins SJ, Jansen GH, Stokin GB, Pimentel J, Hewer E, Collie D, Smith P, Roberts H, Brandel JP, van Duijn C, Pocchiari M, Begue C, Cras P, Will RG, Sanchez-Juan P. Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease. Brain. 2009 Oct;132(Pt 10):2659-68.

2013

739. Allebrandt KV, Amin N, Müller-Myhsok B, Esko T, Teder-Laving M, Azevedo RV, Hayward C, van Mill J, Vogelzangs N, Green EW, Melville SA, Lichtner P, Wichmann HE, Oostra BA, Janssens AC, Campbell H, Wilson JF, Hicks AA, Pramstaller PP, Dogas Z, Rudan I, Merrow M, Penninx B, Kyriacou CP, Metspalu A, van Duijn CM, Meitinger T, Roenneberg T. A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila. Mol Psychiatry. 2013 Jan;18(1):122-32.

740. Ansari M, McKeigue PM, Skerka C, Hayward C, Rudan I, Vitart V, Polasek O, Armbrecht AM, Yates JR, Vatavuk Z, Bencic G, Kolcic I, Oostra BA, VanDuijn CM, Campbell S, Stanton CM, Huffman J, Shu X, Khan JC, Shahid H, Harding SP, Bishop PN, Deary IJ, Moore AT, Dhillon B, Rudan P, Zipfel PF, Sim RB, Hastie ND, Campbell H, Wright AFGenetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration.Hum Mol Genet. 2013 Dec 1;22(23):4857-69.

741. Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, Medland SE, Todt U, McArdle WL, Quaye L, Koiranen M, Ikram MA, Lehtimäki T, Stam AH, Ligthart L, Wedenoja J, Dunham I, Neale BM, Palta P, Hamalainen E, Schürks M, Rose LM, Buring JE, Ridker PM, Steinberg S, Stefansson H, Jakobsson F, Lawlor DA, Evans DM, Ring SM, Färkkilä M, Artto V, Kaunisto MA, Freilinger T, Schoenen J, Frants RR, Pelzer N, Weller CM, Zielman R, Heath AC, Madden PA, Montgomery GW, Martin NG, Borck G, Göbel H, Heinze A, Heinze-Kuhn K, Williams FM, Hartikainen AL, Pouta A, van den Ende J, Uitterlinden AG, Hofman A, Amin N, Hottenga JJ, Vink JM, Heikkilä K, Alexander M, Muller-Myhsok B, Schreiber S, Meitinger T, Wichmann HE, Aromaa A, Eriksson JG, Traynor BJ, Trabzuni D; North American Brain Expression Consortium; UK Brain Expression Consortium, Rossin E, Lage K, Jacobs SB, Gibbs JR, Birney E, Kaprio J, Penninx BW, Boomsma DI, van Duijn C, Raitakari O, Jarvelin MR, Zwart JA, Cherkas L, Strachan DP, Kubisch C, Ferrari MD, van den Maagdenberg AM, Dichgans M, Wessman M, Smith GD, Stefansson K, Daly MJ; the International Headache Genetics Consortium, Nyholt DR, Chasman DI, Palotie A. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nat Genet. 2013 Jun 23.

742. Belonogova NM, Svishcheva GR, van Duijn CM, Aulchenko YS, Axenovich TI. Region-based association analysis of human quantitative traits in related individuals. PLoS One. 2013 Jun 17;8(6):e65395. 

743. Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, Wood AR, Workalemahu T, Hu YJ, Lee SH, Liang L, Lin DY, Min JL, Neale BM, Thorleifsson G, Yang J, Albrecht E, Amin N, Bragg-Gresham JL, Cadby G, den Heijer M, Eklund N, Fischer K, Goel A, Hottenga JJ, Huffman JE, Jarick I, Johansson A, Johnson T, Kanoni S, Kleber ME, König IR, Kristiansson K, Kutalik Z, Lamina C, Lecoeur C, Li G, Mangino M, McArdle WL, Medina-Gomez C, Müller-Nurasyid M, Ngwa JS, Nolte IM, Paternoster L, Pechlivanis S, Perola M, Peters MJ, Preuss M, Rose LM, Shi J, Shungin D, Smith AV, Strawbridge RJ, Surakka I, Teumer A, Trip MD, Tyrer J, Van Vliet-Ostaptchouk JV, Vandenput L, Waite LL, Zhao JH, Absher D, Asselbergs FW, Atalay M, Attwood AP, Balmforth AJ, Basart H, Beilby J, Bonnycastle LL, Brambilla P, Bruinenberg M, Campbell H, Chasman DI, Chines PS, Collins FS, Connell JM, Cookson WO, de Faire U, de Vegt F, Dei M, Dimitriou M, Edkins S, Estrada K, Evans DM, Farrall M, Ferrario MM, Ferrières J, Franke L, Frau F, Gejman PV, Grallert H, Grönberg H, Gudnason V, Hall AS, Hall P, Hartikainen AL, Hayward C, Heard-Costa NL, Heath AC, Hebebrand J, Homuth G, Hu FB, Hunt SE, Hyppönen E, Iribarren C, Jacobs KB, Jansson JO, Jula A, Kähönen M, Kathiresan S, Kee F, Khaw KT, Kivimäki M, Koenig W, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Laitinen JH, Lakka TA, Langenberg C, Launer LJ, Lind L, Lindström J, Liu J, Liuzzi A, Lokki ML, Lorentzon M, Madden PA, Magnusson PK, Manunta P, Marek D, März W, Mateo Leach I, McKnight B, Medland SE, Mihailov E, Milani L, Montgomery GW, Mooser V, Mühleisen TW, Munroe PB, Musk AW, Narisu N, Navis G, Nicholson G, Nohr EA, Ong KK, Oostra BA, Palmer CN, Palotie A, Peden JF, Pedersen N, Peters A, Polasek O, Pouta A, Pramstaller PP, Prokopenko I, Pütter C, Radhakrishnan A, Raitakari O, Rendon A, Rivadeneira F, Rudan I, Saaristo TE, Sambrook JG, Sanders AR, Sanna S, Saramies J, Schipf S, Schreiber S, Schunkert H, Shin SY, Signorini S, Sinisalo J, Skrobek B, Soranzo N, Stančáková A, Stark K, Stephens JC, Stirrups K, Stolk RP, Stumvoll M, Swift AJ, Theodoraki EV, Thorand B, Tregouet DA, Tremoli E, Van der Klauw MM, van Meurs JB, Vermeulen SH, Viikari J, Virtamo J, Vitart V, Waeber G, Wang Z, Widén E, Wild SH, Willemsen G, Winkelmann BR, Witteman JC, Wolffenbuttel BH, Wong A, Wright AF, Zillikens MC, Amouyel P, Boehm BO, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Cupples LA, Cusi D, Dedoussis GV, Erdmann J, Eriksson JG, Franks PW, Froguel P, Gieger C, Gyllensten U, Hamsten A, Harris TB, Hengstenberg C, Hicks AA, Hingorani A, Hinney A, Hofman A, Hovingh KG, Hveem K, Illig T, Jarvelin MR, Jöckel KH, Keinanen-Kiukaanniemi SM, Kiemeney LA, Kuh D, Laakso M, Lehtimäki T, Levinson DF, Martin NG, Metspalu A, Morris AD, Nieminen MS, Njølstad I, Ohlsson C, Oldehinkel AJ, Ouwehand WH, Palmer LJ, Penninx B, Power C, Province MA, Psaty BM, Qi L, Rauramaa R, Ridker PM, Ripatti S, Salomaa V, Samani NJ, Snieder H, Sørensen TI, Spector TD, Stefansson K, Tönjes A, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Vollenweider P, Wallaschofski H, Wareham NJ, Watkins H, Wichmann HE, Wilson JF, Abecasis GR, Assimes TL, Barroso I, Boehnke M, Borecki IB, Deloukas P, Fox CS, Frayling T, Groop LC, Haritunian T, Heid IM, Hunter D, Kaplan RC, Karpe F, Moffatt MF, Mohlke KL, O'Connell JR, Pawitan Y, Schadt EE, Schlessinger D, Steinthorsdottir V, Strachan DP, Thorsteinsdottir U, van Duijn CM, Visscher PM, Di Blasio AM, Hirschhorn JN, Lindgren CM, Morris AP, Meyre D, Scherag A, McCarthy MI, Speliotes EK, North KE, Loos RJ, Ingelsson E. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 2013 Apr 26;45(5):501-12.

744. Bos D, Ikram MA, Isaacs A, Verhaaren BF, Hofman A, van Duijn CM, Witteman JC, van der Lugt A, Vernooij MW. Genetic Loci for coronary calcification and serum lipids relate to aortic and carotid calcification. Circ Cardiovasc Genet. 2013 Feb 1;6(1):47-53. 

745. Broer L, Codd V, Nyholt DR, Deelen J, Mangino M, Willemsen G, Albrecht E, Amin N, Beekman M, de Geus EJ, Henders A, Nelson CP, Steves CJ, Wright MJ, de Craen AJ, Isaacs A, Matthews M, Moayyeri A, Montgomery GW, Oostra BA, Vink JM, Spector TD, Slagboom PE, Martin NG, Samani NJ, van Duijn CM, Boomsma DI. Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. Eur J Hum Genet. 2013 Jan 16

746. Broer L, Demerath EW, Garcia ME, Homuth G, Kaplan RC, Lunetta KL, Tanaka T, Tranah GJ, Walter S, Arnold AM, Atzmon G, Harris TB, Hoffmann W, Karasik D, Kiel DP, Kocher T, Launer LJ, Lohman KK, Rotter JI, Tiemeier H, Uitterlinden AG, Wallaschofski H, Bandinelli S, Dörr M, Ferrucci L, Franceschini N, Gudnason V, Hofman A, Liu Y, Murabito JM, Newman AB, Oostra BA, Psaty BM, Smith AV, van Duijn CM. Association of heat shock proteins with all-cause mortality.Age (Dordr). 2013 Aug;35(4):1367-76.

747. Broer L, Lill CM, Schuur M, Amin N, Roehr JT, Bertram L, Ioannidis JP, van Duijn CM. Distinguishing true from false positives in genomic studies: p values. Eur J Epidemiol. 2013 Feb 1.

748. Buitendijk GH, Rochtchina E, Myers C, van Duijn CM, Lee KE, Klein BE, Meuer SM, de Jong PT, Holliday EG, Tan AG, Uitterlinden AG, Sivakumaran TS, Attia J, Hofman A, Mitchell P, Vingerling JR, Iyengar SK, Janssens AC, Wang JJ, Klein R, Klaver CC. Prediction of Age-related Macular Degeneration in the General Population: The Three Continent AMD Consortium.Ophthalmology. 2013 Dec;120(12):2644-55.

749. Bullock JM, Medway C, Cortina-Borja M, Turton JC, Prince JA, Ibrahim-Verbaas CA, Schuur M, Breteler MM, van Duijn CM, Kehoe PG, Barber R, Coto E, Alvarez V, Deloukas P, Hammond N, Combarros O, Mateo I, Warden DR, Lehmann MG, Belbin O, Brown K, Wilcock GK, Heun R, Kölsch H, Smith AD, Lehmann DJ, Morgan K. Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease. Neurobiol Aging. 2013 Apr;34(4):1309.e1-7. 

750. Byrne EM, Gehrman PR, Medland SE, Nyholt DR, Heath AC, Madden PA, Hickie IB, Van Duijn CM, Henders AK, Montgomery GW, Martin NG, Wray NR; The Chronogen Consortium. A genome-wide association study of sleep habits and insomnia.Am J Med Genet B Neuropsychiatr Genet. 2013 May 31. 

751. Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, Macgregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, Timpson NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, van Leeuwen EM, Wilson JF, Pennell CE, van Duijn CM, de Jong PT, Vingerling JR, Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M; Consortium for Refractive Error and Myopia, Burdon KP, Craig JE, Iyengar SK, Igo RP Jr, Lass JH Jr; The Fuchs’ Genetics Multi-Center Study Group, Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, Höhn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ; Wellcome Trust Case Control Consortium 2, Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions, and Complications Research Group, Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MK, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E, Tai ES, Fan Q, Xu L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, Pärssinen O, Mitchell P,

Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CC, Wong TY, Saw SM, Baird PN. Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error.Am J Hum Genet. 2013 Aug 8;93(2):264-77.

752. Codd V, Nelson CP, Albrecht E, Mangino M, Deelen J, Buxton JL, Hottenga JJ, Fischer K, Esko T, Surakka I, Broer L, Nyholt DR, Mateo Leach I, Salo P, Hägg S, Matthews MK, Palmen J, Norata GD, O'Reilly PF, Saleheen D, Amin N, Balmforth AJ, Beekman M, de Boer RA, Böhringer S, Braund PS, Burton PR, Craen AJ, Denniff M, Dong Y, Douroudis K, Dubinina E, Eriksson JG, Garlaschelli K, Guo D, Hartikainen AL, Henders AK, Houwing-Duistermaat JJ, Kananen L, Karssen LC, Kettunen J, Klopp N, Lagou V, van Leeuwen EM, Madden PA, Mägi R, Magnusson PK, Männistö S, McCarthy MI, Medland SE, Mihailov E, Montgomery GW, Oostra BA, Palotie A, Peters A, Pollard H, Pouta A, Prokopenko I, Ripatti S, Salomaa V, Suchiman HE, Valdes AM, Verweij N, Viñuela A, Wang X, Wichmann HE, Widen E, Willemsen G, Wright MJ, Xia K, Xiao X, van Veldhuisen DJ, Catapano AL, Tobin MD, Hall AS, Blakemore AI, van Gilst WH, Zhu H, Consortium C, Erdmann J, Reilly MP, Kathiresan S, Schunkert H, Talmud PJ, Pedersen NL, Perola M, Ouwehand W, Kaprio J, Martin NG, van Duijn CM, Hovatta I, Gieger C, Metspalu A, Boomsma DI, Jarvelin MR, Slagboom PE, Thompson JR, Spector TD, van der Harst P, Samani NJ. Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet. 2013 Apr;45(4):422-7.

753. Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Mook-Kanamori DO, Coker LH, Longstreth WT Jr, Niessen WJ, Destefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CR Jr, Rivadeneira F, Uitterlinden AG, Knopman DS, Hartikainen AL, Pennell CE, Thiering E, Steegers EA, Hakonarson H, Heinrich J, Palmer LJ, Jarvelin MR, McCarthy MI, Grant SF, Pourcain BS, Timpson NJ, Smith GD, Sovio U; Early Growth Genetics (EGG) Consortium, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Jaddoe VW, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley TH Jr, Schmidt H, Launer LJ, Breteler MM, Decarli C; Early Growth Genetics (EGG) Consortium, Adair LS, Ang W, Atalay M, van Beijsterveldt T, Bergen N, Benke K, Berry D, Coin L, Davis OS, Elliott P, Flexeder C, Frayling T, Gaillard R, Groen-Blokhuis M, Goh LK, Haworth CM, Hadley D, Hedebrand J, Hinney A, Hirschhorn JN, Holloway JW, Holst C, Jan Hottenga J, Horikoshi M, Huikari V, Hypponen E, Kilpeläinen TO, Kirin M, Kowgier M, Lakka HM, Lange LA, Lawlor DA, Lehtimäki T, Lewin A, Lindgren C, Lindi V, Maggi R, Marsh J, Middeldorp C, Millwood I, Murray JC, Nivard M, Nohr EA, Ntalla I, Oken E, Panoutsopoulou K, Pararajasingham J, Rodriguez A, Salem RM, Sebert S, Siitonen N, Strachan DP, Teo YY, Valcárcel B, Willemsen G, Zeggini E, Boomsma DI, Cooper C, Gillman M, Hocher B, Lakka TA, Mohlke KL, Dedoussis GV, Ong KK, Pearson ER, Price TS, Power C, Raitakari OT, Saw SM, Scherag A, Simell O, Wilson JF. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet. 2013 May 29;45(6):713.

754. Cousminer DL, Berry DJ, Timpson NJ, Ang W, Thiering E, Byrne EM, Taal HR, Huikari V, Bradfield JP, Kerkhof M, Groen-Blokhuis MM, Kreiner-Møller E, Marinelli M, Holst C, Leinonen JT, Perry JR, Surakka I, Pietiläinen O, Kettunen J, Anttila V, Kaakinen M, Sovio U, Pouta A, Das S, Lagou V, Power C, Prokopenko I, Evans DM, Kemp JP, St Pourcain B, Ring S, Palotie A, Kajantie E, Osmond C, Lehtimäki T, Viikari JS, Kähönen M, Warrington NM, Lye SJ, Palmer LJ, Tiesler CM, Flexeder C, Montgomery GW, Medland SE, Hofman A, Hakonarson H,

Guxens M, Bartels M, Salomaa V; ReproGen Consortium, Murabito JM, Kaprio J, Sørensen TI, Ballester F, Bisgaard H, Boomsma DI, Koppelman GH, Grant SF, Jaddoe VW, Martin NG, Heinrich J, Pennell CE, Raitakari OT, Eriksson JG, Smith GD, Hyppönen E, Järvelin MR, McCarthy MI, Ripatti S, Widén E; Early Growth Genetics (EGG) Consortium. Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.Hum Mol Genet. 2013 Jul 1;22(13):2735-47.

755. Crosslin DR, McDavid A, Weston N, Zheng X, Hart E, de Andrade M, Kullo IJ, McCarty CA, Doheny KF, Pugh E, Kho A, Hayes MG, Ritchie MD, Saip A, Crawford DC, Crane PK, Newton K, Carrell DS, Gallego CJ, Nalls MA, Li R, Mirel DB, Crenshaw A, Couper DJ, Tanaka T, van Rooij FJ, Chen MH, Smith AV, Zakai NA, Yango Q, Garcia M, Liu Y, Lumley T, Folsom AR, Reiner AP, Felix JF, Dehghan A, Wilson JG, Bis JC, Fox CS, Glazer NL, Cupples LA, Coresh J, Eiriksdottir G, Gudnason V, Bandinelli S, Frayling TM, Chakravarti A, van Duijn CM, Melzer D, Levy D, Boerwinkle E, Singleton AB, Hernandez DG, Longo DL, Witteman JC, Psaty BM, Ferrucci L, Harris TB, O'Donnell CJ, Ganesh SK; CHARGE Hematology Working Group, Larson EB, Carlson CS, Jarvik GP; The electronic Medical Records and Genomics (eMERGE) Network. Genetic variation associated with circulating monocyte count in the eMERGE Network. Hum Mol Genet. 2013 Jan 12.

756. Dastani Z, Johnson T, Kronenberg F, Nelson CP, Assimes TL, März W; CARDIoGRAM Consortium; ADIPOGen Consortium, Richards JB. The shared allelic architecture of adiponectin levels and coronary artery disease.Atherosclerosis. 2013 Jul;229(1):145-8.

757. Demirkan A, Isaacs A, Ugocsai P, Liebisch G, Struchalin M, Rudan I, Wilson JF, Pramstaller PP, Gyllensten U, Campbell H, Schmitz G, Oostra BA, van Duijn CM. Plasma phosphatidylcholine and sphingomyelin concentrations are associated with depression and anxiety symptoms in a Dutch family-based lipidomics study. J Psychiatr Res. 2013 Mar;47(3):357-62. 

758. den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, van der Harst P, Hayward C, den Heijer M, Igl W, Jackson AU, Kutalik Z, Luan J, Kemp JP, Kristiansson K, Ladenvall C, Lorentzon M, Montasser ME, Njajou OT, O'Reilly PF, Padmanabhan S, St Pourcain B, Rankinen T, Salo P, Tanaka T, Timpson NJ, Vitart V, Waite L, Wheeler W, Zhang W, Draisma HH, Feitosa MF, Kerr KF, Lind PA, Mihailov E, Onland-Moret NC, Song C, Weedon MN, Xie W, Yengo L, Absher D, Albert CM, Alonso A, Arking DE, de Bakker PI, Balkau B, Barlassina C, Benaglio P, Bis JC, Bouatia-Naji N, Brage S, Chanock SJ, Chines PS, Chung M, Darbar D, Dina C, Dörr M, Elliott P, Felix SB, Fischer K, Fuchsberger C, de Geus EJ, Goyette P, Gudnason V, Harris TB, Hartikainen AL, Havulinna AS, Heckbert SR, Hicks AA, Hofman A, Holewijn S, Hoogstra-Berends F, Hottenga JJ, Jensen MK, Johansson A, Junttila J, Kääb S, Kanon B, Ketkar S, Khaw KT, Knowles JW, Kooner AS, Kors JA, Kumari M, Milani L, Laiho P, Lakatta EG, Langenberg C, Leusink M, Liu Y, Luben RN, Lunetta KL, Lynch SN, Markus MR, Marques-Vidal P, Leach IM, McArdle WL, McCarroll SA, Medland SE, Miller KA, Montgomery GW, Morrison AC, M Vuml Ller-Nurasyid M, Navarro P, Nelis M, O'Connell JR, O'Donnell CJ, Ong KK, Newman AB, Peters A, Polasek O, Pouta A, Pramstaller PP, Psaty BM, Rao DC, Ring SM, Rossin EJ, Rudan D, Sanna S, Scott RA, Sehmi JS, Sharp S, Shin JT, Singleton AB, Smith AV, Soranzo N, Spector TD, Stewart C, Stringham HM, Tarasov KV, Uitterlinden AG, Vandenput L, Hwang SJ, Whitfield JB, Wijmenga C, Wild SH, Willemsen G, Wilson JF, Witteman JC, Wong A, Wong Q, Jamshidi Y, Zitting P, Boer JM, Boomsma DI, Borecki IB, van Duijn CM, Ekelund U, Forouhi NG, Froguel P, Hingorani A, Ingelsson E, Kivimaki M, Kronmal RA, Kuh D, Lind L, Martin NG, Oostra BA, Pedersen NL, Quertermous T,

Rotter JI, van der Schouw YT, Verschuren WM, Walker M, Albanes D, Arnar DO, Assimes TL, Bandinelli S, Boehnke M, de Boer RA, Bouchard C, Caulfield WL, Chambers JC, Curhan G, Cusi D, Eriksson J, Ferrucci L, van Gilst WH, Glorioso N, de Graaf J, Groop L, Gyllensten U, Hsueh WC, Hu FB, Huikuri HV, Hunter DJ, Iribarren C, Isomaa B, Jarvelin MR, Jula A, Kähönen M, Kiemeney LA, van der Klauw MM, Kooner JS, Kraft P, Iacoviello L, Lehtimäki T, Lokki ML, Mitchell BD, Navis G, Nieminen MS, Ohlsson C, Poulter NR, Qi L, Raitakari OT, Rimm EB, Rioux JD, Rizzi F, Rudan I, Salomaa V, Sever PS, Shields DC, Shuldiner AR, Sinisalo J, Stanton AV, Stolk RP, Strachan DP, Tardif JC, Thorsteinsdottir U, Tuomilehto J, van Veldhuisen DJ, Virtamo J, Viikari J, Vollenweider P, Waeber G, Widen E, Cho YS, Olsen JV, Visscher PM, Willer C, Franke L; Global BPgen Consortium; CARDIoGRAM Consortium, Erdmann J, Thompson JR; PR GWAS Consortium, Pfeufer A; QRS GWAS Consortium, Sotoodehnia N; QT-IGC Consortium, Newton-Cheh C; CHARGE-AF Consortium, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet. 2013 Apr 14

759. Dharuri H, Henneman P, Demirkan A, van Klinken JB, Mook-Kanamori DO, Wang-Sattler R, Gieger C, Adamski J, Hettne K, Roos M, Suhre K, Van Duijn CM; EUROSPAN consortia, van Dijk KW, 't Hoen PA. Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles.BMC Genomics. 2013 Dec 9;14:865.

760. Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Donnelly LA, Ehret GB, Esko T, Feitosa MF, Ferreira T, Fischer K, Fontanillas P, Fraser RM, Freitag DF, Gurdasani D, Heikkilä K, Hyppönen E, Isaacs A, Jackson AU, Johansson A, Johnson T, Kaakinen M, Kettunen J, Kleber ME, Li X, Luan J, Lyytikäinen LP, Magnusson PK, Mangino M, Mihailov E, Montasser ME, Müller-Nurasyid M, Nolte IM, O'Connell JR, Palmer CD, Perola M, Petersen AK, Sanna S, Saxena R, Service SK, Shah S, Shungin D, Sidore C, Song C, Strawbridge RJ, Surakka I, Tanaka T, Teslovich TM, Thorleifsson G, Van den Herik EG, Voight BF, Volcik KA, Waite LL, Wong A, Wu Y, Zhang W, Absher D, Asiki G, Barroso I, Been LF, Bolton JL, Bonnycastle LL, Brambilla P, Burnett MS, Cesana G, Dimitriou M, Doney AS, Döring A, Elliott P, Epstein SE, Eyjolfsson GI, Gigante B, Goodarzi MO, Grallert H, Gravito ML, Groves CJ, Hallmans G, Hartikainen AL, Hayward C, Hernandez D, Hicks AA, Holm H, Hung YJ, Illig T, Jones MR, Kaleebu P, Kastelein JJ, Khaw KT, Kim E, Klopp N, Komulainen P, Kumari M, Langenberg C, Lehtimäki T, Lin SY, Lindström J, Loos RJ, Mach F, McArdle WL, Meisinger C, Mitchell BD, Müller G, Nagaraja R, Narisu N, Nieminen TV, Nsubuga RN, Olafsson I, Ong KK, Palotie A, Papamarkou T, Pomilla C, Pouta A, Rader DJ, Reilly MP, Ridker PM, Rivadeneira F, Rudan I, Ruokonen A, Samani N, Scharnagl H, Seeley J, Silander K, Stančáková A, Stirrups K, Swift AJ, Tiret L, Uitterlinden AG, van Pelt LJ, Vedantam S, Wainwright N, Wijmenga C, Wild SH, Willemsen G, Wilsgaard T, Wilson JF, Young EH, Zhao JH, Adair LS, Arveiler D, Assimes TL, Bandinelli S, Bennett F, Bochud M, Boehm BO, Boomsma DI, Borecki IB, Bornstein SR, Bovet P, Burnier M, Campbell H, Chakravarti A, Chambers JC, Chen YD, Collins FS, Cooper RS, Danesh J, Dedoussis G, de Faire U, Feranil AB, Ferrières J, Ferrucci L, Freimer NB, Gieger C, Groop LC, Gudnason V, Gyllensten U, Hamsten A, Harris TB, Hingorani A, Hirschhorn JN, Hofman A, Hovingh GK, Hsiung CA, Humphries SE, Hunt SC, Hveem K, Iribarren C, Järvelin MR, Jula A, Kähönen M, Kaprio J, Kesäniemi A, Kivimaki M, Kooner JS, Koudstaal PJ, Krauss RM, Kuh D, Kuusisto J, Kyvik KO, Laakso M, Lakka TA, Lind L, Lindgren CM, Martin NG, März W, McCarthy MI, McKenzie CA, Meneton P, Metspalu A, Moilanen L, Morris AD, Munroe PB, Njølstad I, Pedersen NL, Power C, Pramstaller PP, Price JF, Psaty BM, Quertermous T, Rauramaa R, Saleheen D, Salomaa V,

Sanghera DK, Saramies J, Schwarz PE, Sheu WH, Shuldiner AR, Siegbahn A, Spector TD, Stefansson K, Strachan DP, Tayo BO, Tremoli E, Tuomilehto J, Uusitupa M, van Duijn CM, Vollenweider P, Wallentin L, Wareham NJ, Whitfield JB, Wolffenbuttel BH, Altshuler D, Ordovas JM, Boerwinkle E, Palmer CN, Thorsteinsdottir U, Chasman DI, Rotter JI, Franks PW, Ripatti S, Cupples LA, Sandhu MS, Rich SS, Boehnke M, Deloukas P, Mohlke KL, Ingelsson E, Abecasis GR, Daly MJ, Neale BM, Kathiresan S. Common variants associated with plasma triglycerides and risk for coronary artery disease.Nat Genet. 2013 Nov;45(11):1345-52.

761. Erdmann J, Stark K, Esslinger UB, Rumpf PM, Koesling D, de Wit C, Kaiser FJ, Braunholz D, Medack A, Fischer M, Zimmermann ME, Tennstedt S, Graf E, Eck S, Aherrahrou Z, Nahrstaedt J, Willenborg C, Bruse P, Brænne I, Nöthen MM, Hofmann P, Braund PS, Mergia E, Reinhard W, Burgdorf C, Schreiber S, Balmforth AJ, Hall AS, Bertram L, Steinhagen-Thiessen E, Li SC, März W, Reilly M, Kathiresan S, McPherson R, Walter U; CARDIoGRAM, Ott J, Samani NJ, Strom TM, Meitinger T, Hengstenberg C, Schunkert H, Assimes TL, Deloukas P, Holm H, König IR, Roberts R, Stewart AF. Dysfunctional nitric oxide signalling increases risk of myocardial infarction.Nature. 2013 Dec 19;504(7480):432-6.

762. Evans DM, Brion MJ, Paternoster L, Kemp JP, McMahon G, Munafò M, Whitfield JB, Medland SE, Montgomery GW; GIANT Consortium; CRP Consortium; TAG Consortium, Timpson NJ, St Pourcain B, Lawlor DA, Martin NG, Dehghan A, Hirschhorn J, Davey Smith G. Mining the human phenome using allelic scores that index biological intermediates.PLoS Genet. 2013 Oct;9(10):e1003919.

763. Fall T, Hägg S, Mägi R, Ploner A, Fischer K, Horikoshi M, Sarin AP, Thorleifsson G, Ladenvall C, Kals M, Kuningas M, Draisma HH, Ried JS, van Zuydam NR, Huikari V, Mangino M, Sonestedt E, Benyamin B, Nelson CP, Rivera NV, Kristiansson K, Shen HY, Havulinna AS, Dehghan A, Donnelly LA, Kaakinen M, Nuotio ML, Robertson N, de Bruijn RF, Ikram MA, Amin N, Balmforth AJ, Braund PS, Doney AS, Döring A, Elliott P, Esko T, Franco OH, Gretarsdottir S, Hartikainen AL, Heikkilä K, Herzig KH, Holm H, Hottenga JJ, Hyppönen E, Illig T, Isaacs A, Isomaa B, Karssen LC, Kettunen J, Koenig W, Kuulasmaa K, Laatikainen T, Laitinen J, Lindgren C, Lyssenko V, Läärä E, Rayner NW, Männistö S, Pouta A, Rathmann W, Rivadeneira F, Ruokonen A, Savolainen MJ, Sijbrands EJ, Small KS, Smit JH, Steinthorsdottir V, Syvänen AC, Taanila A, Tobin MD, Uitterlinden AG, Willems SM, Willemsen G, Witteman J, Perola M, Evans A, Ferrières J, Virtamo J, Kee F, Tregouet DA, Arveiler D, Amouyel P, Ferrario MM, Brambilla P, Hall AS, Heath AC, Madden PA, Martin NG, Montgomery GW, Whitfield JB, Jula A, Knekt P, Oostra B, van Duijn CM, Penninx BW, Davey Smith G, Kaprio J, Samani NJ, Gieger C, Peters A, Wichmann HE, Boomsma DI, de Geus EJ, Tuomi T, Power C, Hammond CJ, Spector TD, Lind L, Orho-Melander M, Palmer CN, Morris AD, Groop L, Järvelin MR, Salomaa V, Vartiainen E, Hofman A, Ripatti S, Metspalu A, Thorsteinsdottir U, Stefansson K, Pedersen NL, McCarthy MI, Ingelsson E, Prokopenko I; European Network for Genetic and Genomic Epidemiology (ENGAGE) consortium. The role of adiposity in cardiometabolic traits: a mendelian randomization analysis. PLoS Med. 2013 Jun;10(6):e1001474. 

764. Fernández-Rhodes L, Demerath EW, Cousminer DL, Tao R, Dreyfus JG, Esko T, Smith AV, Gudnason V, Harris TB, Launer L, McArdle PF, Yerges-Armstrong LM, Elks CE, Strachan DP, Kutalik Z, Vollenweider P, Feenstra B, Boyd HA, Metspalu A, Mihailov E, Broer L, Zillikens MC, Oostra B, van Duijn CM, Lunetta KL, Perry JR, Murray A, Koller DL, Lai D, Corre T, Toniolo D, Albrecht E, Stöckl D, Grallert H, Gieger C, Hayward C, Polasek O, Rudan I, Wilson JF, He C, Kraft P, Hu FB, Hunter DJ, Hottenga JJ, Willemsen G, Boomsma DI, Byrne EM, Martin NG, Montgomery GW, Warrington NM, Pennell CE, Stolk L, Visser JA, Hofman A, Uitterlinden AG, Rivadeneira F, Lin P, Fisher SL, Bierut LJ, Crisponi L, Porcu E, Mangino M,

Zhai G, Spector TD, Buring JE, Rose LM, Ridker PM, Poole C, Hirschhorn JN, Murabito JM, Chasman DI, Widen E, North KE, Ong KK, Franceschini N. Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent.Am J Epidemiol. 2013 Apr 4.

765. Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Franceschini N, Gaunt TR, Gho JM, Gieger C, Gong Y, Isaacs A, Kleber ME, Leach IM, McDonough CW, Meijs MF, Mellander O, Molony CM, Nolte IM, Padmanabhan S, Price TS, Rajagopalan R, Shaffer J, Shah S, Shen H, Soranzo N, van der Most PJ, Van Iperen EP, van Setten J, Vonk JM, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Boer JM, Boerwinkle E, Burkley B, Burt A, Chakravarti A, Chen W, Cooper-Dehoff RM, Curtis SP, Dreisbach A, Duggan D, Ehret GB, Fabsitz RR, Fornage M, Fox E, Furlong CE, Gansevoort RT, Hofker MH, Hovingh GK, Kirkland SA, Kottke-Marchant K, Kutlar A, Lacroix AZ, Langaee TY, Li YR, Lin H, Liu K, Maiwald S, Malik R; METASTROKE, Murugesan G, Newton-Cheh C, O'Connell JR, Onland-Moret NC, Ouwehand WH, Palmas W, Penninx BW, Pepine CJ, Pettinger M, Polak JF, Ramachandran VS, Ranchalis J, Redline S, Ridker PM, Rose LM, Scharnag H, Schork NJ, Shimbo D, Shuldiner AR, Srinivasan SR, Stolk RP, Taylor HA, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Winkelmann BR, Wyatt S, Young JH, Boehm BO, Caulfield MJ, Chasman DI, Davidson KW, Doevendans PA, Fitzgerald GA, Gums JG, Hakonarson H, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W; LifeLines Cohort Study, März W, Mitchell BD, Murray SS, Oldehinkel AJ, Rader DJ, Reilly MP, Reiner AP, Schadt EE, Silverstein RL, Snieder H, Stanton AV, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Johnson AD, Munroe PB, de Bakker PI, Zhu X, Levy D, Keating BJ, Asselbergs FW. Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet. 2013 Jan 8. 

766. Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.Diabetes. 2013 Mar;62(3):977-86

767. Global Lipids Genetics Consortium, Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Do R, Donnelly LA, Ehret GB, Esko T, Feitosa MF, Ferreira T, Fischer K, Fontanillas P, Fraser RM, Freitag DF, Gurdasani D, Heikkilä K, Hyppönen E, Isaacs A, Jackson AU, Johansson A, Johnson T, Kaakinen M, Kettunen J, Kleber ME, Li X, Luan J, Lyytikäinen LP, Magnusson PK, Mangino M, Mihailov E, Montasser ME, Müller-Nurasyid M, Nolte IM, O'Connell JR, Palmer CD, Perola M, Petersen AK, Sanna S, Saxena R, Service SK, Shah S, Shungin D, Sidore C, Song C, Strawbridge RJ, Surakka I, Tanaka T, Teslovich TM, Thorleifsson G, Van den Herik EG, Voight BF, Volcik KA, Waite LL, Wong A, Wu Y, Zhang W, Absher D, Asiki G, Barroso I, Been LF, Bolton JL, Bonnycastle LL, Brambilla P, Burnett MS, Cesana G, Dimitriou M, Doney AS, Döring A, Elliott P, Epstein SE, Eyjolfsson GI, Gigante B, Goodarzi MO, Grallert H, Gravito ML, Groves CJ, Hallmans G, Hartikainen AL, Hayward C, Hernandez D, Hicks AA, Holm H, Hung YJ, Illig T, Jones MR, Kaleebu P, Kastelein JJ, Khaw KT, Kim E, Klopp N, Komulainen P, Kumari M, Langenberg C, Lehtimäki T, Lin SY, Lindström J, Loos RJ, Mach F, McArdle WL, Meisinger C, Mitchell BD, Müller G, Nagaraja R, Narisu N, Nieminen TV, Nsubuga RN, Olafsson I, Ong KK, Palotie A, Papamarkou T, Pomilla C, Pouta A, Rader DJ, Reilly MP, Ridker PM, Rivadeneira F, Rudan I, Ruokonen A, Samani N, Scharnagl H, Seeley J, Silander K, Stancáková A, Stirrups K, Swift AJ, Tiret L, Uitterlinden AG, van Pelt LJ, Vedantam S, Wainwright N, Wijmenga C, Wild SH, Willemsen G, Wilsgaard T, Wilson JF, Young EH, Zhao JH, Adair LS, Arveiler D, Assimes TL, Bandinelli S, Bennett F, Bochud M, Boehm BO, Boomsma DI, Borecki IB, Bornstein SR, Bovet P, Burnier M, Campbell H, Chakravarti A, Chambers JC, Chen YD, Collins FS, Cooper RS, Danesh J, Dedoussis G, de Faire U, Feranil AB, Ferrières J, Ferrucci L, Freimer NB, Gieger C, Groop LC, Gudnason V, Gyllensten U, Hamsten A, Harris TB, Hingorani A, Hirschhorn JN, Hofman A, Hovingh GK,

Hsiung CA, Humphries SE, Hunt SC, Hveem K, Iribarren C, Järvelin MR, Jula A, Kähönen M, Kaprio J, Kesäniemi A, Kivimaki M, Kooner JS, Koudstaal PJ, Krauss RM, Kuh D, Kuusisto J, Kyvik KO, Laakso M, Lakka TA, Lind L, Lindgren CM, Martin NG, März W, McCarthy MI, McKenzie CA, Meneton P, Metspalu A, Moilanen L, Morris AD, Munroe PB, Njølstad I, Pedersen NL, Power C, Pramstaller PP, Price JF, Psaty BM, Quertermous T, Rauramaa R, Saleheen D, Salomaa V, Sanghera DK, Saramies J, Schwarz PE, Sheu WH, Shuldiner AR, Siegbahn A, Spector TD, Stefansson K, Strachan DP, Tayo BO, Tremoli E, Tuomilehto J, Uusitupa M, vanDuijn CM, Vollenweider P, Wallentin L, Wareham NJ, Whitfield JB, Wolffenbuttel BH, Ordovas JM, Boerwinkle E, Palmer CN, Thorsteinsdottir U, Chasman DI, Rotter JI, Franks PW, Ripatti S, Cupples LA, Sandhu MS, Rich SS, Boehnke M, Deloukas P, Kathiresan S, Mohlke KL, Ingelsson E, Abecasis GR. Discovery and refinement of loci associated with lipid levels.Nat Genet. 2013 Nov;45(11):1274-83. 

768. Graff M, Ngwa JS, Workalemahu T, Homuth G, Schipf S, Teumer A, Völzke H, Wallaschofski H, Abecasis GR, Edward L, Francesco C, Sanna S, Scheet P, Schlessinger D, Sidore C, Xiao X, Wang Z, Chanock SJ, Jacobs KB, Hayes RB, Hu F, Van Dam RM; The GIANT Consortium, Crout RJ, Marazita ML, Shaffer JR, Atwood LD, Fox CS, Heard-Costa NL, White C, Choh AC, Czerwinski SA, Demerath EW, Dyer TD, Towne B, Amin N, Oostra BA, Van Duijn CM, Zillikens MC, Esko T, Nelis M, Nikopensius T, Metspalu A, Strachan DP, Monda K, Qi L, North KE, Cupples LA, Gordon-Larsen P, Berndt SI. Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.Hum Mol Genet. 2013 Jun 5.

769. Grove ML, Yu B, Cochran BJ, Haritunians T, Bis JC, Taylor KD, Hansen M, Borecki IB, Cupples LA, Fornage M, Gudnason V, Harris TB, Kathiresan S, Kraaij R, Launer LJ, Levy D, Liu Y, Mosley T, Peloso GM, Psaty BM, Rich SS, Rivadeneira F, Siscovick DS, Smith AV, Uitterlinden A, van Duijn CM, Wilson JG, O'Donnell CJ, Rotter JI, Boerwinkle E. Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium.PLoS One. 2013 Jul 12;8(7)

770. Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D, Cannas A, Coker LH, de Geus E, De Jager PL, Diez-Roux AV, Purcell S, Hu FB, Rimm EB, Hunter DJ, Jensen MK, Curhan G, Rice K, Penman AD, Rotter JI, Sotoodehnia N, Emeny R, Eriksson JG, Evans DA, Ferrucci L, Fornage M, Gudnason V, Hofman A, Illig T, Kardia S, Kelly-Hayes M, Koenen K, Kraft P, Kuningas M, Massaro JM, Melzer D, Mulas A, Mulder CL, Murray A, Oostra BA, Palotie A, Penninx B, Petersmann A, Pilling LC, Psaty B, Rawal R, Reiman EM, Schulz A, Shulman JM, Singleton AB, Smith AV, Sutin AR, Uitterlinden AG, Völzke H, Widen E, Yaffe K, Zonderman AB, Cucca F, Harris T, Ladwig KH, Llewellyn DJ, Räikkönen K, Tanaka T, van Duijn CM, Grabe HJ, Launer LJ, Lunetta KL, Mosley TH Jr, Newman AB, Tiemeier H, Murabito J. A Genome-Wide Association Study of Depressive Symptoms. Biol Psychiatry. 2013 Jan 2.

771. Hofman A, Darwish Murad S, van Duijn CM, Franco OH, Goedegebure A, Ikram MA, Klaver CC, Nijsten TE, Peeters RP, Stricker BH, Tiemeier HW, Uitterlinden AG, Vernooij MW. The Rotterdam Study: 2014 objectives and design update.Eur J Epidemiol. 2013 Nov;28(11):889-926

772. Hofman A, Darwish Murad S, van Duijn CM, Franco OH, Goedegebure A, Ikram MA, Klaver CC, Nijsten TE, Peeters RP, Stricker BH, Tiemeier HW, Uitterlinden AG, Vernooij MW. The Rotterdam Study: 2014 objectives and design update.Eur J Epidemiol. 2013 Nov;28(11

773. Ho JE, Chen WY, Chen MH, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E,

Emilsson V, Johnson AD, Walter S, Franceschini N, O'Donnell CJ; CARDIoGRAM Consortium; CHARGE Inflammation Working Group, Dehghan A, Lu C, Levy D, Newton-Cheh C; CHARGE Heart Failure Working Group, Lin H, Felix JF, Schreiter ER, Vasan RS, Januzzi JL, Lee RT, Wang TJ, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF. Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling.J Clin Invest. 2013 Oct 1;123(10):4208-18.

774. Holliday EG, Smith AV, Cornes BK, Buitendijk GH, Jensen RA, Sim X, Aspelund T, Aung T, Baird PN, Boerwinkle E, Cheng CY, van Duijn CM, Eiriksdottir G, Gudnason V, Harris T, Hewitt AW, Inouye M, Jonasson F, Klein BE, Launer L, Li X, Liew G, Lumley T, McElduff P, McKnight B, Mitchell P, Psaty BM, Rochtchina E, Rotter JI, Scott RJ, Tay W, Taylor K, Teo YY, Uitterlinden AG, Viswanathan A, Xie S; Wellcome Trust Case Control Consortium 2, Vingerling JR, Klaver CC, Tai ES, Siscovick D, Klein R, Cotch MF, Wong TY, Attia J, Wang JJ. Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. PLoS One. 2013;8(1):e53830.

775. Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B, Evans DM, Charoen P, Kaakinen M, Cousminer DL, Lehtimäki T, Kreiner-Møller E, Warrington NM, Bustamante M, Feenstra B, Berry DJ, Thiering E, Pfab T, Barton SJ, Shields BM, Kerkhof M, van Leeuwen EM, Fulford AJ, Kutalik Z, Zhao JH, den Hoed M, Mahajan A, Lindi V, Goh LK, Hottenga JJ, Wu Y, Raitakari OT, Harder MN, Meirhaeghe A, Ntalla I, Salem RM, Jameson KA, Zhou K, Monies DM, Lagou V, Kirin M, Heikkinen J, Adair LS, Alkuraya FS, Al-Odaib A, Amouyel P, Andersson EA, Bennett AJ, Blakemore AI, Buxton JL, Dallongeville J, Das S, de Geus EJ, Estivill X, Flexeder C, Froguel P, Geller F, Godfrey KM, Gottrand F, Groves CJ, Hansen T, Hirschhorn JN, Hofman A, Hollegaard MV, Hougaard DM, Hyppönen E, Inskip HM, Isaacs A, Jørgensen T, Kanaka-Gantenbein C, Kemp JP, Kiess W, Kilpeläinen TO, Klopp N, Knight BA, Kuzawa CW, McMahon G, Newnham JP, Niinikoski H, Oostra BA, Pedersen L, Postma DS, Ring SM, Rivadeneira F, Robertson NR, Sebert S, Simell O, Slowinski T, Tiesler CM, Tönjes A, Vaag A, Viikari JS, Vink JM, Vissing NH, Wareham NJ, Willemsen G, Witte DR, Zhang H, Zhao J; Meta-Analyses of Glucose- and Insulin-related traits Consortium (MAGIC), Wilson JF, Stumvoll M, Prentice AM, Meyer BF, Pearson ER, Boreham CA, Cooper C, Gillman MW, Dedoussis GV, Moreno LA, Pedersen O, Saarinen M, Mohlke KL, Boomsma DI, Saw SM, Lakka TA, Körner A, Loos RJ, Ong KK, Vollenweider P, van Duijn CM, Koppelman GH, Hattersley AT, Holloway JW, Hocher B, Heinrich J, Power C, Melbye M, Guxens M, Pennell CE, Bønnelykke K, Bisgaard H, Eriksson JG, Widén E, Hakonarson H, Uitterlinden AG, Pouta A, Lawlor DA, Smith GD, Frayling TM, McCarthy MI, Grant SF, Jaddoe VW, Jarvelin MR, Timpson NJ, Prokopenko I, Freathy RM; Early Growth Genetics (EGG) Consortium. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet. 2013 Jan;45(1):76-82

776. Hu YJ, Berndt SI, Gustafsson S, Ganna A; Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Hirschhorn J, North KE, Ingelsson E, Lin DY. Meta-analysis of gene-level associations for rare variants based on single-variant statistics.Am J Hum Genet. 2013 Aug 8;93(2):236-48.

777. International Multiple Sclerosis Genetics Consortium (IMSGC), Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS, Spencer C, Booth D, Goris A, Oturai A, Saarela J, Fontaine B, Hemmer B, Martin C, Zipp F, D'Alfonso S, Martinelli-Boneschi F, Taylor B, Harbo HF, Kockum I, Hillert J, Olsson T, Ban M, Oksenberg JR, Hintzen R, Barcellos LF; Wellcome Trust Case Control Consortium 2 (WTCCC2); International IBD Genetics Consortium (IIBDGC), Agliardi C, Alfredsson L, Alizadeh M, Anderson C, Andrews R,

Søndergaard HB, Baker A, Band G, Baranzini SE, Barizzone N, Barrett J, Bellenguez C, Bergamaschi L, Bernardinelli L, Berthele A, Biberacher V, Binder TM, Blackburn H, Bomfim IL, Brambilla P, Broadley S, Brochet B, Brundin L, Buck D, Butzkueven H, Caillier SJ, Camu W, Carpentier W, Cavalla P, Celius EG, Coman I, Comi G, Corrado L, Cosemans L, Cournu-Rebeix I, Cree BA, Cusi D, Damotte V, Defer G, Delgado SR, Deloukas P, di Sapio A, Dilthey AT, Donnelly P, Dubois B, Duddy M, Edkins S, Elovaara I, Esposito F, Evangelou N, Fiddes B, Field J, Franke A, Freeman C, Frohlich IY, Galimberti D, Gieger C, Gourraud PA, Graetz C, Graham A, Grummel V, Guaschino C, Hadjixenofontos A, Hakonarson H, Halfpenny C, Hall G, Hall P, Hamsten A, Harley J, Harrower T, Hawkins C, Hellenthal G, Hillier C, Hobart J, Hoshi M, Hunt SE, Jagodic M, Jelčić I, Jochim A, Kendall B, Kermode A, Kilpatrick T, Koivisto K, Konidari I, Korn T, Kronsbein H, Langford C, Larsson M, Lathrop M, Lebrun-Frenay C, Lechner-Scott J, Lee MH, Leone MA, Leppä V, Liberatore G, Lie BA, Lill CM, Lindén M, Link J, Luessi F, Lycke J, Macciardi F, Männistö S, Manrique CP, Martin R, Martinelli V, Mason D, Mazibrada G, McCabe C, Mero IL, Mescheriakova J, Moutsianas L, Myhr KM, Nagels G, Nicholas R, Nilsson P, Piehl F, Pirinen M, Price SE, Quach H, Reunanen M, Robberecht W, Robertson NP, Rodegher M, Rog D, Salvetti M, Schnetz-Boutaud NC, Sellebjerg F, Selter RC, Schaefer C, Shaunak S, Shen L, Shields S, Siffrin V, Slee M, Sorensen PS, Sorosina M, Sospedra M, Spurkland A, Strange A, Sundqvist E, Thijs V, Thorpe J, Ticca A, Tienari P, van Duijn C, Visser EM, Vucic S, Westerlind H, Wiley JS, Wilkins A, Wilson JF, Winkelmann J, Zajicek J, Zindler E, Haines JL, Pericak-Vance MA, Ivinson AJ, Stewart G, Hafler D, Hauser SL, Compston A, McVean G, De Jager P, Sawcer SJ, McCauley JL. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.Nat Genet. 2013 Nov;45(11):1353-60.

778. International Multiple Sclerosis Genetics Consortium (IMSGC), Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS, Spencer C, Booth D, Goris A, Oturai A, Saarela J, Fontaine B, Hemmer B, Martin C, Zipp F, D'Alfonso S, Martinelli-Boneschi F, Taylor B, Harbo HF, Kockum I, Hillert J, Olsson T, Ban M, Oksenberg JR, Hintzen R, Barcellos LF; Wellcome Trust Case Control Consortium 2 (WTCCC2); International IBD Genetics Consortium (IIBDGC), Agliardi C, Alfredsson L, Alizadeh M, Anderson C, Andrews R, Søndergaard HB, Baker A, Band G, Baranzini SE, Barizzone N, Barrett J, Bellenguez C, Bergamaschi L, Bernardinelli L, Berthele A, Biberacher V, Binder TM, Blackburn H, Bomfim IL, Brambilla P, Broadley S, Brochet B, Brundin L, Buck D, Butzkueven H, Caillier SJ, Camu W, Carpentier W, Cavalla P, Celius EG, Coman I, Comi G, Corrado L, Cosemans L, Cournu-Rebeix I, Cree BA, Cusi D, Damotte V, Defer G, Delgado SR, Deloukas P, di Sapio A, Dilthey AT, Donnelly P, Dubois B, Duddy M, Edkins S, Elovaara I, Esposito F, Evangelou N, Fiddes B, Field J, Franke A, Freeman C, Frohlich IY, Galimberti D, Gieger C, Gourraud PA, Graetz C, Graham A, Grummel V, Guaschino C, Hadjixenofontos A, Hakonarson H, Halfpenny C, Hall G, Hall P, Hamsten A, Harley J, Harrower T, Hawkins C, Hellenthal G, Hillier C, Hobart J, Hoshi M, Hunt SE, Jagodic M, Jelčić I, Jochim A, Kendall B, Kermode A, Kilpatrick T, Koivisto K, Konidari I, Korn T, Kronsbein H, Langford C, Larsson M, Lathrop M, Lebrun-Frenay C, Lechner-Scott J, Lee MH, Leone MA, Leppä V, Liberatore G, Lie BA, Lill CM, Lindén M, Link J, Luessi F, Lycke J, Macciardi F, Männistö S, Manrique CP, Martin R, Martinelli V, Mason D, Mazibrada G, McCabe C, Mero IL, Mescheriakova J, Moutsianas L, Myhr KM, Nagels G, Nicholas R, Nilsson P, Piehl F, Pirinen M, Price SE, Quach H, Reunanen M, Robberecht W, Robertson NP, Rodegher M, Rog D, Salvetti M, Schnetz-Boutaud NC, Sellebjerg F, Selter RC, Schaefer C, Shaunak S, Shen L, Shields S, Siffrin V, Slee M, Sorensen PS, Sorosina M, Sospedra M, Spurkland A, Strange A, Sundqvist E, Thijs V, Thorpe J, Ticca A, Tienari P, van Duijn C, Visser EM, Vucic S, Westerlind H, Wiley JS, Wilkins A, Wilson JF, Winkelmann J, Zajicek J, Zindler E, Haines JL, Pericak-Vance MA, Ivinson AJ, Stewart G, Hafler D, Hauser SL, Compston A, McVean G, De Jager P, Sawcer SJ, McCauley JL. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.Nat Genet. 2013 Nov;45(11):1353-60

779. Isaacs A, Willems SM, Bos D, Dehghan A, Hofman A, Ikram MA, Uitterlinden AG, Oostra BA, Franco OH, Witteman JC, van Duijn CM. Risk Scores of Common Genetic Variants for Lipid Levels Influence Atherosclerosis and Incident Coronary Heart Disease. Arterioscler Thromb Vasc Biol. 2013 Jun 13.

780. Janssen SF, Gorgels TG, Ramdas WD, Klaver CC, van Duijn CM, Jansonius NM, Bergen AA. The vast complexity of primary open angle glaucoma: Disease genes, risks, molecular mechanisms and pathobiology.Prog Retin Eye Res. 2013 Nov;37:31-67.

781. Jensen RA, Sim X, Li X, Cotch MF, Ikram MK, Holliday EG, Eiriksdottir G, Harris TB, Jonasson F, Klein BE, Launer LJ, Smith AV, Boerwinkle E, Cheung N, Hewitt AW, Liew G, Mitchell P, Wang JJ, Attia J, Scott R, Glazer NL, Lumley T, McKnight B, Psaty BM, Taylor K, Hofman A, de Jong PT, Rivadeneira F, Uitterlinden AG, Tay WT, Teo YY, Seielstad M, Liu J, Cheng CY, Saw SM, Aung T, Ganesh SK, O'Donnell CJ, Nalls MA, Wiggins KL, Kuo JZ; Blue Mountains Eye Study GWAS team; CKDGen Consortium, van Duijn CM, Gudnason V, Klein R, Siscovick DS, Rotter JI, Tai ES, Vingerling J, Wong TY. Genome-Wide Association Study of Retinopathy in Individuals without Diabetes. PLoS One. 2013;8(2):e54232.

782. Jonsson T, Stefansson H, Steinberg S, Jonsdottir I, Jonsson PV, Snaedal J, Bjornsson S, Huttenlocher J, Levey AI, Lah JJ, Rujescu D, Hampel H, Giegling I, Andreassen OA, Engedal K, Ulstein I, Djurovic S, Ibrahim-Verbaas C, Hofman A, Ikram MA, van Duijn CM, Thorsteinsdottir U, Kong A, Stefansson K. Variant of TREM2 associated with the risk of Alzheimer's disease. N Engl J Med. 2013 Jan 10;368(2):107-16.

783. Kiezun A, Pulit SL, Francioli LC, van Dijk F, Swertz M, Boomsma DI, van Duijn CM, Slagboom PE, van Ommen GJ, Wijmenga C; Genome of the Netherlands Consortium, de Bakker PI, Sunyaev SR. Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency. PLoS Genet. 2013 Feb;9(2)

784. Klug GM, Wand H, Simpson M, Boyd A, Law M, Masters CL, Matej R, Howley R, Farrell M, Breithaupt M, Zerr I, van Duijn C, Ibrahim-Verbaas C, Mackenzie J, Will RG, Brandel JP, Alperovitch A, Budka H, Kovacs GG, Jansen GH, Coulthard M, Collins SJ. Intensity of human prion disease surveillance predicts observed disease incidence.J Neurol Neurosurg Psychiatry. 2013 Dec;84(12):1372-7.

785. Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, Destefano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Hollingworth P, Ramirez A, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F; European Alzheimer's Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer's Disease (GERAD); Alzheimer's Disease Genetic Consortium (ADGC); Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), Moebus

S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.Nat Genet. 2013 Dec;45(12):1452-8.

786. Lieb W, Jansen H, Loley C, Pencina MJ, Nelson CP, Newton-Cheh C, Kathiresan S, Reilly MP, Assimes TL, Boerwinkle E, Hall AS, Hengstenberg C, Laaksonen R, McPherson R, Thorsteinsdottir U, Ziegler A, Peters A, Thompson JR, König IR, Erdmann J, Samani NJ, Vasan RS, Schunkert H; CARDIoGRAM, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF. Genetic predisposition to higher blood pressure increases coronary artery disease risk.Hypertension. 2013 May;61(5):995-1001

787. Li H, Gan W, Lu L, Dong X, Han X, Hu C, Yang Z, Sun L, Bao W, Li P, He M, Sun L, Wang Y, Zhu J, Ning Q, Tang Y, Zhang R, Wen J, Wang D, Zhu X, Guo K, Zuo X, Guo X, Yang H, Zhou X; DIAGRAM Consortium; AGEN-T2D Consortium, Zhang X, Qi L, Loos RJ, Hu FB, Wu T, Liu Y, Liu L, Yang Z, Hu R, Jia W, Ji L, Li Y, Lin X. A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. Diabetes. 2013 Jan;62(1):291-8. 

788. Lopes MC, Hysi PG, Verhoeven VJ, Macgregor S, Hewitt AW, Montgomery G, Cumberland P, Vingerling JR, Young T, van Duijn CM, Oostra B, Uitterlinden AG, Rahi JS, Mackey DA, Klaver CC, Andrew T, Hammond CJ. Identification of a candidate gene for astigmatism. Invest Ophthalmol Vis Sci. 2013 Jan 15.

789. Lu Y, Vitart V, Burdon KP, Khor CC, Bykhovskaya Y, Mirshahi A, Hewitt AW, Koehn D, Hysi PG, Ramdas WD, Zeller T, Vithana EN, Cornes BK, Tay WT, Tai ES, Cheng CY, Liu J, Foo JN, Saw SM, Thorleifsson G, Stefansson K, Dimasi DP, Mills RA, Mountain J, Ang W, Hoehn R, Verhoeven VJ, Grus F, Wolfs R, Castagne R, Lackner KJ, Springelkamp H, Yang J, Jonasson F, Leung DY, Chen LJ, Tham CC, Rudan I, Vatavuk Z, Hayward C, Gibson J, Cree AJ, Macleod A, Ennis S, Polasek O, Campbell H, Wilson JF, Viswanathan AC, Fleck B, Li X, Siscovick D, Taylor KD, Rotter JI, Yazar S, Ulmer M, Li J, Yaspan BL, Ozel AB, Richards JE, Moroi SE, Haines JL, Kang JH, Pasquale LR, Allingham RR, Ashley-Koch A; NEIGHBOR Consortium, Mitchell P, Wang JJ, Wright AF, Pennell C, Spector TD, Young TL, Klaver CC, Martin NG, Montgomery GW, Anderson MG, Aung T, Willoughby CE, Wiggs JL, Pang CP, Thorsteinsdottir U, Lotery AJ, Hammond CJ, van Duijn CM, Hauser MA, Rabinowitz YS, Pfeiffer N, Mackey DA, Craig JE, Macgregor S, Wong TY. Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Nat Genet. 2013 Jan 6.

790. Mendelian Randomisation Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes.Diabetes. 2013 Jul 8.

791. Oldenbeuving AW, de Kort PL, Kappelle LJ, van Duijn CM, Roks G. Delirium in the acute phase

after stroke and the role of the apolipoprotein E gene.Am J Geriatr Psychiatry. 2013 Oct;21(10

792. Oosterveer DM, Versmissen J, Defesche JC, Sivapalaratnam S, Yazdanpanah M, Mulder M, van der Zee L, Uitterlinden AG, van Duijn CM, Hofman A, Kastelein JJ, Aulchenko YS, Sijbrands EJ. Low-density lipoprotein receptor mutations generate synthetic genome-wide associations.Eur J Hum Genet. 2013 May;21(5):563-6.

793. Parsa A, Fuchsberger C, Köttgen A, O'Seaghdha CM, Pattaro C, de Andrade M, Chasman DI, Teumer A, Endlich K, Olden M, Chen MH, Tin A, Kim YJ, Taliun D, Li M, Feitosa M, Gorski M, Yang Q, Hundertmark C, Foster MC, Glazer N, Isaacs A, Rao M, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Couraki V, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Hofer E, Hu F, Demirkan A, Oostra BA, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Döring A, Wichmann HE, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Colhoun H, Doney A, Robino A, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, van Duijn CM, Borecki I, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Bochud M, Heid IM, Siscovick DS, Fox CS, Kao WL, Böger CA. Common variants in mendelian kidney disease genes and their association with renal function.J Am Soc Nephrol. 2013 Dec;24(12):2105-17.

794. Patsopoulos NA, Barcellos LF, Hintzen RQ, Schaefer C, van Duijn CM, Noble JA, Raj T; IMSGC; ANZgene, Gourraud PA, Stranger BE, Oksenberg J, Olsson T, Taylor BV, Sawcer S, Hafler DA, Carrington M, De Jager PL, de Bakker PI. Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects.PLoS Genet. 2013 Nov;9(11)

795. Peters MJ, Broer L, Willemen HL, Eiriksdottir G, Hocking LJ, Holliday KL, Horan MA, Meulenbelt I, Neogi T, Popham M, Schmidt CO, Soni A, Valdes AM, Amin N, Dennison EM, Eijkelkamp N, Harris TB, Hart DJ, Hofman A, Huygen FJ, Jameson KA, Jones GT, Launer LJ, Kerkhof HJ, de Kruijf M, McBeth J, Kloppenburg M, Ollier WE, Oostra B, Payton A, Rivadeneira F, Smith BH, Smith AV, Stolk L, Teumer A, Thomson W, Uitterlinden AG, Wang K, van Wingerden SH, Arden NK, Cooper C, Felson D, Gudnason V, Macfarlane GJ, Pendleton N, Slagboom PE, Spector TD, Völzke H, Kavelaars A, van Duijn CM, Williams FM, van Meurs JB. Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region. Ann Rheum Dis. 2013 Mar;72(3):427-36.

796. Pichler I, Del Greco M F, Gögele M, Lill CM, Bertram L, Do CB, Eriksson N, Foroud T, Myers RH; PD GWAS Consortium, Nalls M, Keller MF; International Parkinson's Disease Genomics Consortium; Wellcome Trust Case Control Consortium 2, Benyamin B, Whitfield JB; Genetics of Iron Status Consortium, Pramstaller PP, Hicks AA, Thompson JR, Minelli C.

797. Pistis G, Okonkwo SU, Traglia M, Sala C, Shin SY, Masciullo C, Buetti I, Massacane R, Mangino M, Thein SL, Spector TD, Ganesh S; CHARGE Consortium Hematology Working, Pirastu N, Gasparini P, Soranzo N, Camaschella C, Hart D, Green MR, Toniolo D. ied Genome wide association analysis of a founder population identifTAF3 as a gene for MCHC in humans.PLoS One. 2013 Jul 31;8(7):e69206.

798. Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, Ferreira T, Gustafsson S, Locke AE, Mathieson I, Scherag A, Vedantam S, Wood AR, Liang L, Steinthorsdottir V, Thorleifsson G, Dermitzakis ET, Dimas AS, Karpe F, Min JL, Nicholson G, Clegg DJ, Person T, Krohn JP, Bauer S, Buechler C, Eisinger K; DIAGRAM Consortium, Bonnefond A, Froguel P; MAGIC Investigators, Hottenga JJ, Prokopenko I, Waite LL, Harris TB, Smith AV, Shuldiner AR, McArdle WL, Caulfield MJ, Munroe PB, Grönberg H, Chen YD, Li G, Beckmann JS, Johnson T, Thorsteinsdottir U, Teder-Laving M, Khaw KT, Wareham NJ, Zhao JH, Amin N, Oostra BA, Kraja AT, Province MA, Cupples LA, Heard-Costa NL, Kaprio J, Ripatti S, Surakka I, Collins FS, Saramies J, Tuomilehto J, Jula A, Salomaa V, Erdmann J, Hengstenberg C, Loley C, Schunkert H, Lamina C, Wichmann HE, Albrecht E, Gieger C, Hicks AA, Johansson A, Pramstaller PP, Kathiresan S, Speliotes EK, Penninx B, Hartikainen AL, Jarvelin MR, Gyllensten U, Boomsma DI, Campbell H, Wilson JF, Chanock SJ, Farrall M, Goel A, Medina-Gomez C, Rivadeneira F, Estrada K, Uitterlinden AG, Hofman A, Zillikens MC, den Heijer M, Kiemeney LA, Maschio A, Hall P, Tyrer J, Teumer A, Völzke H, Kovacs P, Tönjes A, Mangino M, Spector TD, Hayward C, Rudan I, Hall AS, Samani NJ, Attwood AP, Sambrook JG, Hung J, Palmer LJ, Lokki ML, Sinisalo J, Boucher G, Huikuri H, Lorentzon M, Ohlsson C, Eklund N, Eriksson JG, Barlassina C, Rivolta C, Nolte IM, Snieder H, Van der Klauw MM, Van Vliet-Ostaptchouk JV, Gejman PV, Shi J, Jacobs KB, Wang Z, Bakker SJ, Mateo Leach I, Navis G, van der Harst P, Martin NG, Medland SE, Montgomery GW, Yang J, Chasman DI, Ridker PM, Rose LM, Lehtimäki T, Raitakari O, Absher D, Iribarren C, Basart H, Hovingh KG, Hyppönen E, Power C, Anderson D, Beilby JP, Hui J, Jolley J, Sager H, Bornstein SR, Schwarz PE, Kristiansson K, Perola M, Lindström J, Swift AJ, Uusitupa M, Atalay M, Lakka TA, Rauramaa R, Bolton JL, Fowkes G, Fraser RM, Price JF, Fischer K, Krjutå Kov K, Metspalu A, Mihailov E, Langenberg C, Luan J, Ong KK, Chines PS, Keinanen-Kiukaanniemi SM, Saaristo TE, Edkins S, Franks PW, Hallmans G, Shungin D, Morris AD, Palmer CN, Erbel R, Moebus S, Nöthen MM, Pechlivanis S, Hveem K, Narisu N, Hamsten A, Humphries SE, Strawbridge RJ, Tremoli E, Grallert H, Thorand B, Illig T, Koenig W, Müller-Nurasyid M, Peters A, Boehm BO, Kleber ME, März W, Winkelmann BR, Kuusisto J, Laakso M, Arveiler D, Cesana G, Kuulasmaa K, Virtamo J, Yarnell JW, Kuh D, Wong A, Lind L, de Faire U, Gigante B, Magnusson PK, Pedersen NL, Dedoussis G, Dimitriou M, Kolovou G, Kanoni S, Stirrups K, Bonnycastle LL, Njølstad I, Wilsgaard T, Ganna A, Rehnberg E, Hingorani A, Kivimaki M, Kumari M, Assimes TL, Barroso I, Boehnke M, Borecki IB, Deloukas P, Fox CS, Frayling T, Groop LC, Haritunians T, Hunter D, Ingelsson E, Kaplan R, Mohlke KL, O'Connell JR, Schlessinger D, Strachan DP, Stefansson K, van Duijn CM, Abecasis GR, McCarthy MI, Hirschhorn JN, Qi L, Loos RJ, Lindgren CM, North KE, Heid IM. Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. PLoS Genet. 2013 Jun;9(6):e1003500.

799. Reiner AP, Hartiala J, Zeller T, Bis JC, Dupuis J, Fornage M, Baumert J, Kleber ME, Wild PS, Baldus S, Bielinski SJ, Fontes JD, Illig T, Keating BJ, Lange LA, Ojeda F, Müller-Nurasyid M, Munzel TF, Psaty BM, Rice K, Rotter JI, Schnabel RB, Tang WH, Thorand B, Erdmann J; CARDIoGRAM Consortium, Jacobs DR Jr, Wilson JG, Koenig W, Tracy RP, Blankenberg S, März W, Gross MD, Benjamin EJ, Hazen SL, Allayee H. Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia.Hum Mol Genet.

2013 Aug 15;22(16):3381-93.

800. Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, Barnard J, Baumeister SE, Benke KS, Bielak LF, Boatman JA, Boyle PA, Davies G, de Leeuw C, Eklund N, Evans DS, Ferhmann R, Fischer K, Gieger C, Gjessing HK, Hägg S, Harris JR, Hayward C, Holzapfel C, Ibrahim-Verbaas CA, Ingelsson E, Jacobsson B, Joshi PK, Jugessur A, Kaakinen M, Kanoni S, Karjalainen J, Kolcic I, Kristiansson K, Kutalik Z, Lahti J, Lee SH, Lin P, Lind PA, Liu Y, Lohman K, Loitfelder M, McMahon G, Vidal PM, Meirelles O, Milani L, Myhre R, Nuotio ML, Oldmeadow CJ, Petrovic KE, Peyrot WJ, Polasek O, Quaye L, Reinmaa E, Rice JP, Rizzi TS, Schmidt H, Schmidt R, Smith AV, Smith JA, Tanaka T, Terracciano A, van der Loos MJ, Vitart V, Völzke H, Wellmann J, Yu L, Zhao W, Allik J, Attia JR, Bandinelli S, Bastardot F, Beauchamp J, Bennett DA, Berger K, Bierut LJ, Boomsma DI, Bültmann U, Campbell H, Chabris CF, Cherkas L, Chung MK, Cucca F, de Andrade M, De Jager PL, De Neve JE, Deary IJ, Dedoussis GV, Deloukas P, Dimitriou M, Eiriksdottir G, Elderson MF, Eriksson JG, Evans DM, Faul JD, Ferrucci L, Garcia ME, Grönberg H, Gudnason V, Hall P, Harris JM, Harris TB, Hastie ND, Heath AC, Hernandez DG, Hoffmann W, Hofman A, Holle R, Holliday EG, Hottenga JJ, Iacono WG, Illig T, Järvelin MR, Kähönen M, Kaprio J, Kirkpatrick RM, Kowgier M, Latvala A, Launer LJ, Lawlor DA, Lehtimäki T, Li J, Lichtenstein P, Lichtner P, Liewald DC, Madden PA, Magnusson PK, Mäkinen TE, Masala M, McGue M, Metspalu A, Mielck A, Miller MB, Montgomery GW, Mukherjee S, Nyholt DR, Oostra BA, Palmer LJ, Palotie A, Penninx B, Perola M, Peyser PA, Preisig M, Räikkönen K, Raitakari OT, Realo A, Ring SM, Ripatti S, Rivadeneira F, Rudan I, Rustichini A, Salomaa V, Sarin AP, Schlessinger D, Scott RJ, Snieder H, St Pourcain B, Starr JM, Sul JH, Surakka I, Svento R, Teumer A; The LifeLines Cohort Study, Tiemeier H, van Rooij FJ, Van Wagoner DR, Vartiainen E, Viikari J, Vollenweider P, Vonk JM, Waeber G, Weir DR, Wichmann HE, Widen E, Willemsen G, Wilson JF, Wright AF, Conley D, Davey-Smith G, Franke L, Groenen PJ, Hofman A, Johannesson M, Kardia SL, Krueger RF, Laibson D, Martin NG, Meyer MN, Posthuma D, Thurik AR, Timpson NJ, Uitterlinden AG, van Duijn CM, Visscher PM, Benjamin DJ, Cesarini D, Koellinger PD. GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment. Science. 2013 May 30. 

801. Rivera NV, Carreras-Torres R, Roncarati R, Viviani-Anselmi C, De Micco F, Mezzelani A, Koch W, Hoppmann P, Kastrati A, Stewart AF, Chen L, Roberts R, Karssen LC, Amin N, Trimarco V, Izzo R, Iaccarino G, Condorelli G, Puca AA, Pagnotta P, Airoldi F, Trimarco B, van Duijn CM, Condorelli G, Briguori C. Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes. BMC Med Genet. 2013 Jan 23;14:11.

802. Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, Rudnicka AR, Trompet S, Mälarstig A, Baumert J, Bis JC, Guo X, Hottenga JJ, Shin SY, Lopez LM, Lahti J, Tanaka T, Yanek LR, Oudot-Mellakh T, Wilson JF, Navarro P, Huffman JE, Zemunik T, Redline S, Mehra R, Pulanic D, Rudan I, Wright AF, Kolcic I, Polasek O, Wild SH, Campbell H, Curb JD, Wallace R, Liu S, Eaton CB, Becker DM, Becker LC, Bandinelli S, Räikkönen K, Widen E, Palotie A, Fornage M, Green D, Gross M, Davies G, Harris SE, Liewald DC, Starr JM, Williams FM, Grant PJ, Spector TD, Strawbridge RJ, Silveira A, Sennblad B, Rivadeneira F, Uitterlinden AG, Franco OH, Hofman A, van Dongen J, Willemsen G, Boomsma DI, Yao J, Swords Jenny N, Haritunians T, McKnight B, Lumley T, Taylor KD, Rotter JI, Psaty BM, Peters A, Gieger C, Illig T, Grotevendt A, Homuth G, Völzke H, Kocher T, Goel A, Franzosi MG, Seedorf U, Clarke R, Steri M, Tarasov KV, Sanna S, Schlessinger D, Stott DJ, Sattar N, Buckley BM, Rumley A, Lowe GD, McArdle WL, Chen MH, Tofler GH, Song J, Boerwinkle E, Folsom AR, Rose LM, Franco-Cereceda A, Teichert M, Ikram MA, Mosley TH, Bevan S, Dichgans M, Rothwell PM, Sudlow CL, Hopewell JC, Chambers JC,

Saleheen D, Kooner JS, Danesh J, Nelson CP, Erdmann J, Reilly MP, Kathiresan S, Schunkert H, Morange PE, Ferrucci L, Eriksson JG, Jacobs D, Deary IJ, Soranzo N, Witteman JC, de Geus EJ, Tracy RP, Hayward C, Koenig W, Cucca F, Jukema JW, Eriksson P, Seshadri S, Markus HS, Watkins H, Samani NJ; VTE Consortium; STROKE Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2); C4D Consortium; CARDIoGRAM Consortium, Wallaschofski H, Smith NL, Tregouet D, Ridker PM, Tang W, Strachan DP, Hamsten A, O'Donnell CJ. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.Circulation. 2013 Sep 17;128(12):1310-24

803. Saxena R, Saleheen D, Been LF, Garavito ML, Braun T, Bjonnes A, Young R, Ho WK, Rasheed A, Frossard P, Sim X, Hassanali N, Radha V, Chidambaram M, Liju S, Rees SD, Ng DP, Wong TY, Yamauchi T, Hara K, Tanaka Y, Hirose H, McCarthy MI, Morris AP; DIAGRAM; MuTHER; AGEN, Basit A, Barnett AH, Katulanda P, Matthews D, Mohan V, Wander GS, Singh JR, Mehra NK, Ralhan S, Kamboh MI, Mulvihill JJ, Maegawa H, Tobe K, Maeda S, Cho YS, Tai ES, Kelly MA, Chambers JC, Kooner JS, Kadowaki T, Deloukas P, Rader DJ, Danesh J, Sanghera DK.Genome-widGee association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.Diabetes. 2013 May;62(5):1746-55.

804. Schork AJ, Thompson WK, Pham P, Torkamani A, Roddey JC, Sullivan PF, Kelsoe JR, O'Donovan MC, Furberg H; Tobacco and Genetics Consortium; Bipolar Disorder Psychiatric Genomics Consortium; Schizophrenia Psychiatric Genomics Consortium, Schork NJ, Andreassen OA, Dale AM. All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs.PLoS Genet. 2013 Apr;9(4):e1003449

805. Serum iron levels and the risk of Parkinson disease: a mendelian randomization study.PLoS Med. 2013 Jun;10(6):e1001462. doi: 10.1371/journal.pmed.1001462. Epub 2013 Jun 4. Erratum in: PLoS Med. 2013 Jun;10(6). doi:10.1371/annotation/c4d81646-0c0e-4a3e-9425-b220bae2d8b6.

806. Sim X, Jensen RA, Ikram MK, Cotch MF, Li X, Macgregor S, Xie J, Smith AV, Boerwinkle E, Mitchell P, Klein R, Klein BE, Glazer NL, Lumley T, McKnight B, Psaty BM, de Jong PT, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, Aspelund T, Eiriksdottir G, Harris TB, Jonasson F, Launer LJ; Wellcome Trust Case Control Consortium 2, Attia J, Baird PN, Harrap S, Holliday EG, Inouye M, Rochtchina E, Scott RJ, Viswanathan A; Global BPGen Consortium, Li G, Smith NL, Wiggins KL, Kuo JZ, Taylor KD, Hewitt AW, Martin NG, Montgomery GW, Sun C, Young TL, Mackey DA, van Zuydam NR, Doney AS, Palmer CN, Morris AD, Rotter JI, Tai ES, Gudnason V, Vingerling JR, Siscovick DS, Wang JJ, Wong TY. Genetic Loci for retinal arteriolar microcirculation. PLoS One. 2013 Jun 12;8(6):e65804.

807. Singaraja RR, Sivapalaratnam S, Hovingh K, Dubé MP, Castro-Perez J, Collins HL, Adelman SJ, Riwanto M, Manz J, Hubbard B, Tietjen I, Wong K, Mitnaul LJ, van Heek M, Lin L, Roddy TA, McEwen J, Dallinge-Thie G, van Vark-van der Zee L, Verwoert G, Winther M, van Duijn C, Hofman A, Trip MD, Marais AD, Asztalos B, Landmesser U, Sijbrands E, Kastelein JJ, Hayden MR. The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans.Circ Cardiovasc Genet. 2013 Feb 1;6(1):54-62.

808. Smith CE, Ngwa J, Tanaka T, Qi Q, Wojczynski MK, Lemaitre RN, Anderson JS, Manichaikul A, Mikkilä V, van Rooij FJ, Ye Z, Bandinelli S, Frazier-Wood AC, Houston DK, Hu F, Langenberg C, McKeown NM, Mozaffarian D, North KE, Viikari J, Zillikens MC, Djoussé L,

Hofman A, Kähönen M, Kabagambe EK, Loos RJ, Saylor GB, Forouhi NG, Liu Y, Mukamal KJ, Chen YD, Tsai MY, Uitterlinden AG, Raitakari O, van Duijn CM, Arnett DK, Borecki IB, Cupples LA, Ferrucci L, Kritchevsky SB, Lehtimäki T, Qi L, Rotter JI, Siscovick DS, Wareham NJ, Witteman JC, Ordovás JM, Nettleton JA. Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies. Int J Obes (Lond). 2013 Jan 29.

809. Stam AH, Weller CM, Janssens AC, Aulchenko YS, Oostra BA, Frants RR, van den Maagdenberg AM, Ferrari MD, van Duijn CM, Gisela MT. Migraine is not associated with enhanced atherosclerosis. Cephalalgia. 2013 Mar;33(4):228-235.

810. Stambolian D, Wojciechowski R, Oexle K, Pirastu M, Li X, Raffel L, Cotch MF, Chew E, Klein B, Klein R, Wong T, Simpson CL, Klaver C, van Duijn C, Verhoeven V, Baird P, Vitart V, Paterson A, Mitchell P, Saw SM, Fossarello M, Kazmierkiewicz K, Murgia F, Portas L, Schache M, Richardson A, Xie J, Wang JJ, Rochtchina E; DCCT/EDIC Research Group, Viswanathan A, Hayward C, Wright A, Polasek O, Campbell H, Rudan I, Oostra B, Uitterlinden A, Hofman A, Rivadeneira F, Amin N, Karssen L, Vingerling J, Hosseini SM, Döring A, Bettecken T, Vatavuk Z, Gieger C, Wichmann HE, Wilson J, Fleck B, Foster P, Topouzis F, McGuffin P, Sim X, Inouye M, Holliday E, Attia J, Scott R, Rotter J, Meitinger T, Bailey-Wilson J. Meta-Analysis of Genome-wide Association Studies in 5 cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error. Hum Mol Genet. 2013 Mar 7.

811. Taal HR, St Pourcain B, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, Kaakinen M, Kreiner-Møller E, Bradfield JP, Freathy RM, Geller F, Guxens M, Cousminer DL, Kerkhof M, Timpson NJ, Ikram MA, Beilin LJ, Bønnelykke K, Buxton JL, Charoen P, Chawes BL, Eriksson J, Evans DM, Hofman A, Kemp JP, Kim CE, Klopp N, Lahti J, Lye SJ, McMahon G, Mentch FD, Müller-Nurasyid M, O'Reilly PF, Prokopenko I, Rivadeneira F, Steegers EA, Sunyer J, Tiesler C, Yaghootkar H; Cohorts for Heart and Aging Research in Genetic Epidemiology (CHARGE) Consortium, Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Coker LH, Longstreth WT Jr, Niessen WJ, Destefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CR Jr, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley TH Jr, Schmidt H, Launer LJ, Breteler MM, Decarli C, Breteler MM, Debette S, Fornage M, Gudnason V, Launer LJ, van der Lugt A, Mosley TH Jr, Seshadri S, Smith AV, Vernooij MW; Early Genetics & Lifecourse Epidemiology (EAGLE) Consortium, Ang W, van Beijsterveldt T, Bergen N, Benke K, Berry D, Bradfield JP, Charoen P, Coin L, Cousminer DL, Das S, Elliott P, Evans DM, Frayling T, Freathy RM, Gaillard R, Groen-Blokhuis M, Guxens M, Hadley D, Hottenga JJ, Huikari V, Hypponen E, Kaakinen M, Kowgier M, Lawlor DA, Lewin A, Lindgren C, Marsh J, Middeldorp C, Millwood I, Mook-Kanamori DO, Nivard M, O'Reilly PF, Palmer LJ, Prokopenko I, Rodriguez A, Sebert S, Sovio U, St Pourcain B, Standl M, Strachan DP, Sunyer J, Taal HR, Thiering E, Tiesler C, Uitterlinden AG, Valcárcel B, Warrington NM, White S, Willemsen G, Yaghootkar H, Boomsma DI, Estivill X, Grant SF, Hakonarson H, Hattersley AT, Heinrich J, Jaddoe VW, Jarvelin MR, McCarthy MI, Pennell CE, Power C, Timpson NJ, Widen E, Blakemore AI, Chiavacci RM, Feenstra B, Fernandez-Banet J, Grant SF, Hartikainen AL, van der Heijden AJ, Iñiguez C, Lathrop M, McArdle WL, Mølgaard A, Newnham JP, Palmer LJ, Palotie A, Pouta A, Ring SM, Sovio U, Standl M, Uitterlinden AG, Wichmann HE, Vissing NH, Decarli C, van Duijn CM, McCarthy MI, Koppelman GH, Estivill X, Hattersley AT, Melbye M, Bisgaard H, Pennell CE, Widen E, Hakonarson H, Smith GD, Heinrich J, Jarvelin MR, Jaddoe VW; Early Growth Genetics (EGG) Consortium, Adair LS, Ang W, Atalay M, van Beijsterveldt T, Bergen N, Benke K, Berry D, Bradfield JP, Charoen P, Coin L, Cousminer DL, Das S, Davis OS, Elliott P, Evans

DM, Feenstra B, Flexeder C, Frayling T, Freathy RM, Gaillard R, Geller F, Groen-Blokhuis M, Goh LK, Guxens M, Haworth CM, Hadley D, Hedebrand J, Hinney A, Hirschhorn JN, Holloway JW, Holst C, Hottenga JJ, Horikoshi M, Huikari V, Hypponen E, Iñiguez C, Kaakinen M, Kilpeläinen TO, Kirin M, Kowgier M, Lakka HM, Lange LA, Lawlor DA, Lehtimäki T, Lewin A, Lindgren C, Lindi V, Maggi R, Marsh J, Middeldorp C, Millwood I, Mook-Kanamori DO, Murray JC, Nivard M, Nohr EA, Ntalla I, Oken E, O'Reilly PF, Palmer LJ, Panoutsopoulou K, Pararajasingham J, Prokopenko I, Rodriguez A, Salem RM, Sebert S, Siitonen N, Sovio U, St Pourcain B, Strachan DP, Sunyer J, Taal HR, Teo YY, Thiering E, Tiesler C, Uitterlinden AG, Valcárcel B, Warrington NM, White S, Willemsen G, Yaghootkar H, Zeggini E, Boomsma DI, Cooper C, Estivill X, Gillman M, Grant SF, Hakonarson H, Hattersley AT, Heinrich J, Hocher B, Jaddoe VW, Jarvelin MR, Lakka TA, McCarthy MI, Melbye M, Mohlke KL, Dedoussis GV, Ong KK, Pearson ER, Pennell CE, Price TS, Power C, Raitakari OT, Saw SM, Scherag A, Simell O, Timpson NJ, Widen E, Wilson JF. Common variants at 12q15 and 12q24 are associated with infant head circumference. Nat Genet. 2013 May 29;45(6):713.

812. Tabassum R, Chauhan G, Dwivedi OP, Mahajan A, Jaiswal A, Kaur I, Bandesh K, Singh T, Mathai BJ, Pandey Y, Chidambaram M, Sharma A, Chavali S, Sengupta S, Ramakrishnan L, Venkatesh P, Aggarwal SK, Ghosh S, Prabhakaran D, Srinath RK, Saxena M, Banerjee M, Mathur S, Bhansali A, Shah VN, Madhu SV, Marwaha RK, Basu A, Scaria V, McCarthy MI; DIAGRAM; INDICO, Venkatesan R, Mohan V, Tandon N, Bharadwaj D. Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.Diabetes. 2013 Mar;62(3):977-86.

813. The AMD Gene Consortium, Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP Jr, Buitendijk GH, Sim X, Weeks DE, Guymer RH, Merriam JE, Francis PJ, Hannum G, Agarwal A, Armbrecht AM, Audo I, Aung T, Barile GR, Benchaboune M, Bird AC, Bishop PN, Branham KE, Brooks M, Brucker AJ, Cade WH, Cain MS, Campochiaro PA, Chan CC, Cheng CY, Chew EY, Chin KA, Chowers I, Clayton DG, Cojocaru R, Conley YP, Cornes BK, Daly MJ, Dhillon B, Edwards AO, Evangelou E, Fagerness J, Ferreyra HA, Friedman JS, Geirsdottir A, George RJ, Gieger C, Gupta N, Hagstrom SA, Harding SP, Haritoglou C, Heckenlively JR, Holz FG, Hughes G, Ioannidis JP, Ishibashi T, Joseph P, Jun G, Kamatani Y, Katsanis N, N Keilhauer C, Khan JC, Kim IK, Kiyohara Y, Klein BE, Klein R, Kovach JL, Kozak I, Lee CJ, Lee KE, Lichtner P, Lotery AJ, Meitinger T, Mitchell P, Mohand-Saïd S, Moore AT, Morgan DJ, Morrison MA, Myers CE, Naj AC, Nakamura Y, Okada Y, Orlin A, Ortube MC, Othman MI, Pappas C, Park KH, Pauer GJ, Peachey NS, Poch O, Priya RR, Reynolds R, Richardson AJ, Ripp R, Rudolph G, Ryu E, Sahel JA, Schaumberg DA, Scholl HP, Schwartz SG, Scott WK, Shahid H, Sigurdsson H, Silvestri G, Sivakumaran TA, Smith RT, Sobrin L, Souied EH, Stambolian DE, Stefansson H, Sturgill-Short GM, Takahashi A, Tosakulwong N, Truitt BJ, Tsironi EE, Uitterlinden AG, van Duijn CM, Vijaya L, Vingerling JR, Vithana EN, Webster AR, Wichmann HE, Winkler TW, Wong TY, Wright AF, Zelenika D, Zhang M, Zhao L, Zhang K, Klein ML, Hageman GS, Lathrop GM, Stefansson K, Allikmets R, Baird PN, Gorin MB, Wang JJ, Klaver CC, Seddon JM, Pericak-Vance MA, Iyengar SK, Yates JR, Swaroop A, Weber BH, Kubo M, Deangelis MM, Léveillard T, Thorsteinsdottir U, Haines JL, Farrer LA, Heid IM, Abecasis GR. Seven new loci associated with age-related macular degeneration. Nat Genet. 2013 Mar 3.

814. The Blue Mountains Eye Study (BMES) and The Wellcome Trust Case Control Consortium 2 (WTCCC2). Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. Hum Mol Genet. 2013 Jul 7

815. Thorgeirsson TE, Gudbjartsson DF, Sulem P, Besenbacher S, Styrkarsdottir U, Thorleifsson G,

Walters GB; TAG Consortium; Oxford-GSK Consortium; ENGAGE consortium, Furberg H, Sullivan PF, Marchini J, McCarthy MI, Steinthorsdottir V, Thorsteinsdottir U, Stefansson K. A common biological basis of obesity and nicotine addiction.Transl Psychiatry. 2013 Oct 1;3:e308.

816. Tsepilov YA, Ried JS, Strauch K, Grallert H, van Duijn CM, Axenovich TI, Aulchenko YS. Development and application of genomic control methods for genome-wide association studies using non-additive models.PLoS One. 2013 Dec 16;8(12):e81431

817. van den Berg L, Henneman P, Willems van Dijk K, Delemarre-van de Waal HA, Oostra BA, van Duijn CM, Janssens AC. Heritability of dietary food intake patterns.Acta Diabetol. 2013 Oct;50(5):721-6.

818. van der Loos MJ, Rietveld CA, Eklund N, Koellinger PD, Rivadeneira F, Abecasis GR, Ankra-Badu GA, Baumeister SE, Benjamin DJ, Biffar R, Blankenberg S, Boomsma DI, Cesarini D, Cucca F, de Geus EJ, Dedoussis G, Deloukas P, Dimitriou M, Eiriksdottir G, Eriksson J, Gieger C, Gudnason V, Höhne B, Holle R, Hottenga JJ, Isaacs A, Järvelin MR, Johannesson M, Kaakinen M, Kähönen M, Kanoni S, Laaksonen MA, Lahti J, Launer LJ, Lehtimäki T, Loitfelder M, Magnusson PK, Naitza S, Oostra BA, Perola M, Petrovic K, Quaye L, Raitakari O, Ripatti S, Scheet P, Schlessinger D, Schmidt CO, Schmidt H, Schmidt R, Senft A, Smith AV, Spector TD, Surakka I, Svento R, Terracciano A, Tikkanen E, van Duijn CM, Viikari J, Völzke H, Wichmann HE, Wild PS, Willems SM, Willemsen G, van Rooij FJ, Groenen PJ, Uitterlinden AG, Hofman A, Thurik AR. The molecular genetic architecture of self-employment. PLoS One. 2013 Apr 4;8(4):e60542.

819. van Pelt ED, Mescheriakova JY, Makhani N, Ketelslegers IA, Neuteboom RF, Kundu S, Broer L, Janssens C, Catsman-Berrevoets CE, van Duijn CM, Banwell B, Bar-Or A, Hintzen RQ. Risk genes associated with pediatric-onset MS but not with monophasic acquired CNS demyelination.Neurology. 2013 Dec 3;81(23):1996-2001

820. Verhaaren BF, Vernooij MW, Koudstaal PJ, Uitterlinden AG, van Duijn CM, Hofman A, Breteler MM, Ikram MA. Alzheimer's disease genes and cognition in the nondemented general population. Biol Psychiatry. 2013 Mar 1;73(5):429-34.

821. Verhoeven VJ, Hysi PG, Wojciechowski R, Fan Q, Guggenheim JA, Höhn R, Macgregor S, Hewitt AW, Nag A, Cheng CY, Yonova-Doing E, Zhou X, Ikram MK, Buitendijk GH, McMahon G, Kemp JP, Pourcain BS, Simpson CL, Mäkelä KM, Lehtimäki T, Kähönen M, Paterson AD, Hosseini SM, Wong HS, Xu L, Jonas JB, Pärssinen O, Wedenoja J, Yip SP, Ho DW, Pang CP, Chen LJ, Burdon KP, Craig JE, Klein BE, Klein R, Haller T, Metspalu A, Khor CC, Tai ES, Aung T, Vithana E, Tay WT, Barathi VA; Consortium for Refractive Error and Myopia (CREAM), Chen P, Li R, Liao J, Zheng Y, Ong RT, Döring A; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Evans DM, Timpson NJ, Verkerk AJ, Meitinger T, Raitakari O, Hawthorne F, Spector TD, Karssen LC, Pirastu M, Murgia F, Ang W; Wellcome Trust Case Control Consortium 2 (WTCCC2), Mishra A, Montgomery GW, Pennell CE, Cumberland PM, Cotlarciuc I, Mitchell P, Wang JJ, Schache M, Janmahasatian S, Jr RP, Lass JH, Chew E, Iyengar SK; Fuchs' Genetics Multi-Center Study Group, Gorgels TG, Rudan I, Hayward C, Wright AF, Polasek O, Vatavuk Z, Wilson JF, Fleck B, Zeller T, Mirshahi A, Müller C, Uitterlinden AG, Rivadeneira F, Vingerling JR, Hofman A, Oostra BA, Amin N, Bergen AA, Teo YY, Rahi JS, Vitart V, Williams C, Baird PN, Wong TY, Oexle K, Pfeiffer N, Mackey DA, Young TL, van Duijn CM, Saw SM, Bailey-Wilson JE, Stambolian D, Klaver CC, Hammond CJ. Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and

myopia.Nat Genet. 2013 May 29;45(6):712. 

822. Verhoeven VJ, Hysi PG, Wojciechowski R, Fan Q, Guggenheim JA, Höhn R, Macgregor S, Hewitt AW, Nag A, Cheng CY, Yonova-Doing E, Zhou X, Ikram MK, Buitendijk GH, McMahon G, Kemp JP, Pourcain BS, Simpson CL, Mäkelä KM, Lehtimäki T, Kähönen M, Paterson AD, Hosseini SM, Wong HS, Xu L, Jonas JB, Pärssinen O, Wedenoja J, Yip SP, Ho DW, Pang CP, Chen LJ, Burdon KP, Craig JE, Klein BE, Klein R, Haller T, Metspalu A, Khor CC, Tai ES, Aung T, Vithana E, Tay WT, Barathi VA; Consortium for Refractive Error and Myopia (CREAM), Chen P, Li R, Liao J, Zheng Y, Ong RT, Döring A; The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Evans DM, Timpson NJ, Verkerk AJ, Meitinger T, Raitakari O, Hawthorne F, Spector TD, Karssen LC, Pirastu M, Murgia F, Ang W; Wellcome Trust Case Control Consortium 2 (WTCCC2), Mishra A, Montgomery GW, Pennell CE, Cumberland PM, Cotlarciuc I, Mitchell P, Wang JJ, Schache M, Janmahasathian S, Jr RP, Lass JH, Chew E, Iyengar SK; The Fuchs' Genetics Multi-Center Study Group, Gorgels TG, Rudan I, Hayward C, Wright AF, Polasek O, Vatavuk Z, Wilson JF, Fleck B, Zeller T, Mirshahi A, Müller C, Uitterlinden AG, Rivadeneira F, Vingerling JR, Hofman A, Oostra BA, Amin N, Bergen AA, Teo YY, Rahi JS, Vitart V, Williams C, Baird PN, Wong TY, Oexle K, Pfeiffer N, Mackey DA, Young TL, van Duijn CM, Saw SM, Bailey-Wilson JE, Stambolian D, Klaver CC, Hammond CJ. Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet. 2013 Feb 10.

823. Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Wood AR, Michaëlsson K, Vandenput L, Zgaga L, Yerges-Armstrong LM, McCarthy MI, Dupuis J, Kaakinen M, Kleber ME, Jameson K, Arden N, Raitakari O, Viikari J, Lohman KK, Ferrucci L, Melhus H, Ingelsson E, Byberg L, Lind L, Lorentzon M, Salomaa V, Campbell H, Dunlop M, Mitchell BD, Herzig KH, Pouta A, Hartikainen AL; Genetic Investigation of Anthropometric Traits-GIANT Consortium, Streeten EA, Theodoratou E, Jula A, Wareham NJ, Ohlsson C, Frayling TM, Kritchevsky SB, Spector TD, Richards JB, Lehtimäki T, Ouwehand WH, Kraft P, Cooper C, März W, Power C, Loos RJ, Wang TJ, Järvelin MR, Whittaker JC, Hingorani AD, Hyppönen E. Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med. 2013 Feb;10(2)

824. Wolffsohn JS, van der Worp E, de Brabander J; GP Consensus Group. Consensus on recording of gas permeable contact lens fit.Cont Lens Anterior Eye. 2013 Dec;36(6):299-303

825. Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancáková A, Buxbaum SG, Lyytikäinen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, Zhao JH, Ballantyne CM, Xie W, Bergman RN, Boehnke M, el Bouazzaoui F, Collins FS, Dunn SH, Dupuis J, Forouhi NG, Gillson C, Hattersley AT, Hong J, Kähönen M, Kuusisto J, Kedenko L, Kronenberg F, Doria A, Assimes TL, Ferrannini E, Hansen T, Hao K, Häring H, Knowles JW, Lindgren CM, Nolan JJ, Paananen J, Pedersen O, Quertermous T, Smith U; GENESIS Consortium; RISC Consortium, Lehtimäki T, Liu CT, Loos RJ, McCarthy MI, Morris AD, Vasan RS, Spector TD, Teslovich TM, Tuomilehto J, van Dijk KW, Viikari JS, Zhu N, Langenberg C, Ingelsson E, Semple RK, Sinaiko AR, Palmer CN, Walker M, Lam KS, Paulweber B, Mohlke KL, van Duijn C, Raitakari OT, Bidulescu A, Wareham NJ, Laakso M, Waterworth DM, Lawlor DA, Meigs JB, Richards JB, Frayling TM. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes.Diabetes. 2013 Oct;62(10):3589-98

826. Zhan X, Larson DE, Wang C, Koboldt DC, Sergeev YV, Fulton RS, Fulton LL, Fronick CC, Branham KE, Bragg-Gresham J, Jun G, Hu Y, Kang HM, Liu D, Othman M, Brooks M, Ratnapriya R, Boleda A, Grassmann F, von Strachwitz C, Olson LM, Buitendijk GH, Hofman A, van Duijn CM, Cipriani V, Moore AT, Shahid H, Jiang Y, Conley YP, Morgan DJ, Kim IK, Johnson MP, Cantsilieris S, Richardson AJ, Guymer RH, Luo H, Ouyang H, Licht C, Pluthero FG, Zhang MM, Zhang K, Baird PN, Blangero J, Klein ML, Farrer LA, Deangelis MM, Weeks DE, Gorin MB, Yates JR, Klaver CC, Pericak-Vance MA, Haines JL, Weber BH, Wilson RK, Heckenlively JR, Chew EY, Stambolian D, Mardis ER, Swaroop A, Abecasis GR. Identification of a rare coding variant in complement 3 associated with age-related macular degeneration.Nat Genet. 2013 Nov;45(11):1375-9.

2014

827. Adams HH, Verhaaren BF, Vrooman HA, Uitterlinden AG, Hofman A, van Duijn CM, van der Lugt A, Niessen WJ, Vernooij MW, Ikram MA. TMEM106B influences volume of left-sided temporal lobe and interhemispheric structures in the general population. Biol Psychiatry. 2014 Sep;76(6):503-8.

828. Albrecht E, Sillanpää E, Karrasch S, Alves AC, Codd V, Hovatta I, Buxton JL, Nelson CP, Broer L, Hägg S, Mangino M, Willemsen G, Surakka I, Ferreira MA, Amin N, Oostra BA, Bäckmand HM, Peltonen M, Sarna S, Rantanen T, Sipilä S, Korhonen T, Madden PA, Gieger C, Jörres RA, Heinrich J, Behr J, Huber RM, Peters A, Strauch K, Wichmann HE, Waldenberger M, Blakemore AI, de Geus EJ, Nyholt DR, Henders AK, Piirilä PL, Rissanen A, Magnusson PK, Viñuela A, Pietiläinen KH, Martin NG, Pedersen NL, Boomsma DI, Spector TD, van Duijn CM, Kaprio J, Samani NJ, Jarvelin MR, Schulz H. Telomere length in circulating leukocytes is associated with lung function and disease. Eur Respir J. 2014 Apr;43(4):983-92.

829. Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, Bradford Y, Tarasov KV, Dörr M, Müller-Nurasyid M, Lahtinen AM, Nolte IM, Smith AV, Bis JC, Isaacs A, Newhouse SJ, Evans DS, Post WS, Waggott D, Lyytikäinen LP, Hicks AA, Eisele L, Ellinghaus D, Hayward C, Navarro P, Ulivi S, Tanaka T, Tester DJ, Chatel S, Gustafsson S, Kumari M, Morris RW, Naluai ÅT, Padmanabhan S, Kluttig A, Strohmer B, Panayiotou AG, Torres M, Knoflach M, Hubacek JA, Slowikowski K, Raychaudhuri S, Kumar RD, Harris TB, Launer LJ, Shuldiner AR, Alonso A, Bader JS, Ehret G, Huang H, Kao WH, Strait JB, Macfarlane PW, Brown M, Caulfield MJ, Samani NJ, Kronenberg F, Willeit J; CARe Consortium; COGENT Consortium, Smith JG, Greiser KH, Meyer Zu Schwabedissen H, Werdan K, Carella M, Zelante L, Heckbert SR, Psaty BM, Rotter JI, Kolcic I, Polašek O, Wright AF, Griffin M, Daly MJ; DCCT/EDIC, Arnar DO, Hólm H, Thorsteinsdottir U; eMERGE Consortium, Denny JC, Roden DM, Zuvich RL, Emilsson V, Plump AS, Larson MG, O'Donnell CJ, Yin X, Bobbo M, D'Adamo AP, Iorio A, Sinagra G, Carracedo A, Cummings SR, Nalls MA, Jula A, Kontula KK, Marjamaa A, Oikarinen L, Perola M, Porthan K, Erbel R, Hoffmann P, Jöckel KH, Kälsch H, Nöthen MM; HRGEN Consortium, den Hoed M, Loos RJ, Thelle DS, Gieger C, Meitinger T, Perz S, Peters A, Prucha H, Sinner MF, Waldenberger M, de Boer RA, Franke L, van der Vleuten PA, Beckmann BM, Martens E, Bardai A, Hofman N, Wilde AA, Behr ER, Dalageorgou C, Giudicessi JR, Medeiros-Domingo A, Barc J, Kyndt F, Probst V, Ghidoni A, Insolia R, Hamilton RM, Scherer SW, Brandimarto J, Margulies K, Moravec CE, del Greco M F, Fuchsberger C, O'Connell JR, Lee WK, Watt GC, Campbell H, Wild SH, El Mokhtari NE, Frey

N, Asselbergs FW, Mateo Leach I, Navis G, van den Berg MP, van Veldhuisen DJ, Kellis M, Krijthe BP, Franco OH, Hofman A, Kors JA, Uitterlinden AG, Witteman JC, Kedenko L, Lamina C, Oostra BA, Abecasis GR, Lakatta EG, Mulas A, Orrú M, Schlessinger D, Uda M, Markus MR, Völker U, Snieder H, Spector TD, Ärnlöv J, Lind L, Sundström J, Syvänen AC, Kivimaki M, Kähönen M, Mononen N, Raitakari OT, Viikari JS, Adamkova V, Kiechl S, Brion M, Nicolaides AN, Paulweber B, Haerting J, Dominiczak AF, Nyberg F, Whincup PH, Hingorani AD, Schott JJ, Bezzina CR, Ingelsson E, Ferrucci L, Gasparini P, Wilson JF, Rudan I, Franke A, Mühleisen TW, Pramstaller PP, Lehtimäki TJ, Paterson AD, Parsa A, Liu Y, van Duijn CM, Siscovick DS, Gudnason V, Jamshidi Y, Salomaa V, Felix SB, Sanna S, Ritchie MD, Stricker BH, Stefansson K, Boyer LA, Cappola TP, Olsen JV, Lage K, Schwartz PJ, Kääb S, Chakravarti A, Ackerman MJ, Pfeufer A, de Bakker PI, Newton-Cheh C. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nat Genet. 2014 Aug;46(8):826-36.

830. Avery CL, Sitlani CM, Arking DE, Arnett DK, Bis JC, Boerwinkle E, et al. Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval. Pharmacogenomics J. 2014 Feb;14(1):6-13.

831. Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, Gögele M, Anderson D, Broer L, Podmore C, Luan J, Kutalik Z, Sanna S, van der Meer P, Tanaka T, Wang F, Westra HJ, Franke L, Mihailov E, Milani L, Häldin J, Winkelmann J, Meitinger T, Thiery J, Peters A, Waldenberger M, Rendon A, Jolley J, Sambrook J, Kiemeney LA, Sweep FC, Sala CF, Schwienbacher C, Pichler I, Hui J, Demirkan A, Isaacs A, Amin N, Steri M, Waeber G, Verweij N, Powell JE, Nyholt DR, Heath AC, Madden PA, Visscher PM, Wright MJ, Montgomery GW, Martin NG, Hernandez D, Bandinelli S, van der Harst P, Uda M, Vollenweider P, Scott RA, Langenberg C, Wareham NJ; InterAct Consortium, van Duijn C, Beilby J, Pramstaller PP, Hicks AA, Ouwehand WH, Oexle K, Gieger C, Metspalu A, Camaschella C, Toniolo D, Swinkels DW, Whitfield JB. Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nat Commun. 2014 Oct 29;5:4926.

832. van den Berg SM, de Moor MH, McGue M, Pettersson E, Terracciano A, Verweij KJ, Amin N, Derringer J, Esko T, van Grootheest G, Hansell NK, Huffman J, Konte B, Lahti J, Luciano M, Matteson LK, Viktorin A, Wouda J, Agrawal A, Allik J, Bierut L, Broms U, Campbell H, Smith GD, Eriksson JG, Ferrucci L, Franke B, Fox JP, de Geus EJ, Giegling I, Gow AJ, Grucza R, Hartmann AM, Heath AC, Heikkilä K, Iacono WG, Janzing J, Jokela M, Kiemeney L, Lehtimäki T, Madden PA, Magnusson PK, Northstone K, Nutile T, Ouwens KG, Palotie A, Pattie A, Pesonen AK, Polasek O, Pulkkinen L, Pulkki-Råback L, Raitakari OT, Realo A, Rose RJ, Ruggiero D, Seppälä I, Slutske WS, Smyth DC, Sorice R, Starr JM, Sutin AR, Tanaka T, Verhagen J, Vermeulen S, Vuoksimaa E, Widen E, Willemsen G, Wright MJ, Zgaga L, Rujescu D, Metspalu A, Wilson JF, Ciullo M, Hayward C, Rudan I, Deary IJ, Räikkönen K, Arias Vasquez A, Costa PT, Keltikangas-Järvinen L, van Duijn CM, Penninx BW, Krueger RF, Evans DM, Kaprio J, Pedersen NL, Martin NG, Boomsma DI. Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory. Behav Genet. 2014 Jul;44(4):295-313.

833. Bis JC, DeStefano A, Liu X, Brody JA, Choi SH, Verhaaren BF, Debette S, Ikram MA, Shahar E, Butler KR Jr, Gottesman RF, Muzny D, Kovar CL, Psaty BM, Hofman A, Lumley T, Gupta M, Wolf PA, van Duijn C, Gibbs RA, Mosley TH, Longstreth WT Jr, Boerwinkle E, Seshadri S, Fornage M. Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium. PLoS One. 2014 Jun

24;9(6):e99798.

834. Boada M, Antúnez C, Ramírez-Lorca R, DeStefano AL, González-Pérez A, Gayán J, López-Arrieta J, Ikram MA, Hernández I, Marín J, Galán JJ, Bis JC, Mauleón A, Rosende-Roca M, Moreno-Rey C, Gudnasson V, Morón FJ, Velasco J, Carrasco JM, Alegret M, Espinosa A, Vinyes G, Lafuente A, Vargas L, Fitzpatrick AL; Alzheimer’s Disease Neuroimaging Initiative, Launer LJ, Sáez ME, Vázquez E, Becker JT, López OL, Serrano-Ríos M, Tárraga L, van Duijn CM, Real LM, Seshadri S, Ruiz A. ATP5H/KCTD2 locus is associated with Alzheimer's disease risk. Mol Psychiatry. 2014 Jun;19(6):682-7.

835. Boccia S, Mc Kee M, Adany R, Boffetta P, Burton H, Cambon-Thomsen A, Cornel MC, Gray M, Jani A, Knoppers BM, Khoury MJ, Meslin EM, Van Duijn CM, Villari P, Zimmern R, Cesario A, Puggina A, Colotto M, Ricciardi W. Beyond public health genomics: proposals from an international working group. Eur J Public Health. 2014 Dec;24(6):877-9.

836. Boffetta P, Bobak M, Borsch-Supan A, Brenner H, Eriksson S, Grodstein F, Jansen E, Jenab M, Juerges H, Kampman E, Kee F, Kuulasmaa K, Park Y, Tjonneland A, van Duijn C, Wilsgaard T, Wolk A, Trichopoulos D, Bamia C, Trichopoulou A. The Consortium on Health and Ageing: Network of Cohorts in Europe and the United States (CHANCES) project-design, population and data harmonization of a large-scale, international study. Eur J Epidemiol. 2014 Dec;29(12):929-36.

837. Boomsma DI, Wijmenga C, Slagboom EP, Swertz MA, Karssen LC, Abdellaoui A, Ye K, Guryev V, Vermaat M, van Dijk F, Francioli LC, Hottenga JJ, Laros JF, Li Q, Li Y, Cao H, Chen R, Du Y, Li N, Cao S, van Setten J, Menelaou A, Pulit SL, Hehir-Kwa JY, Beekman M, Elbers CC, Byelas H, de Craen AJ, Deelen P, Dijkstra M, den Dunnen JT, de Knijff P, Houwing-Duistermaat J, Koval V, Estrada K, Hofman A, Kanterakis A, Enckevort Dv, Mai H, Kattenberg M, van Leeuwen EM, Neerincx PB, Oostra B, Rivadeneira F, Suchiman EH, Uitterlinden AG, Willemsen G, Wolffenbuttel BH, Wang J, de Bakker PI, van Ommen GJ, van Duijn CM. The Genome of the Netherlands: design, and project goals. Eur J Hum Genet. 2014 Feb;22(2):221-7.

838. Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA, Orwoll ES, Parimi N, Psaty BM, Rivadeneira F, Rotter JI, Seshadri S, Singleton A, Tiemeier H, Uitterlinden AG, Zhao W, Bandinelli S, Bennett DA, Ferrucci L, Gudnason V, Harris TB, Karasik D, Launer LJ, Perls TT, Slagboom PE, Tranah GJ, Weir DR, Newman AB, van Duijn CM, Murabito JM. GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):110-8.

839. Broer L, Raschenberger J, Deelen J, Mangino M, Codd V, Pietiläinen KH, Albrecht E, Amin N, Beekman M, de Craen AJ, Gieger C, Haun M, Henneman P, Herder C, Hovatta I, Laser A, Kedenko L, Koenig W, Kollerits B, Moilanen E, Oostra BA, Paulweber B, Quaye L, Rissanen A, Roden M, Surakka I, Valdes AM, Vuolteenaho K, Thorand B, van Dijk KW, Kaprio J, Spector TD, Slagboom PE, Samani NJ, Kronenberg F, van Duijn CM, Ladwig KH. Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants. Eur J Epidemiol. 2014 Sep;29(9):629-38.

840. Chouraki V, De Bruijn RF, Chapuis J, Bis JC, Reitz C, Schraen S, Ibrahim-Verbaas CA, Grenier-Boley B, Delay C, Rogers R, Demiautte F, Mounier A, Fitzpatrick AL; Alzheimer's Disease

Neuroimaging Initiative, Berr C, Dartigues JF, Uitterlinden AG, Hofman A, Breteler M, Becker JT, Lathrop M, Schupf N, Alpérovitch A, Mayeux R, van Duijn CM, Buée L, Amouyel P, Lopez OL, Ikram MA, Tzourio C, Lambert JC. A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly. Mol Psychiatry. 2014 Dec;19(12):1326-35.

841. de Bruijn RF, Janssen JA, Brugts MP, van Duijn CM, Hofman A, Koudstaal PJ, Ikram MA. Insulin-like growth factor-I receptor stimulating activity is associated with dementia. J Alzheimers Dis. 2014;42(1):137-42.

842. Buitendijk GH, Amin N, Hofman A, van Duijn CM, Vingerling JR, Klaver CC. Direct-to-Consumer Personal Genome Testing for Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2014 Aug 21;55(10):6167-74.

843. Chouraki V, De Bruijn RF, Chapuis J, Bis JC, Reitz C, Schraen S, Ibrahim-Verbaas CA, Grenier-Boley B, Delay C, Rogers R, Demiautte F, Mounier A, Fitzpatrick AL; Alzheimer's Disease Neuroimaging Initiative, Berr C, Dartigues JF, Uitterlinden AG, Hofman A, Breteler M, Becker JT, Lathrop M, Schupf N, Alpérovitch A, Mayeux R, van Duijn CM, Buée L, Amouyel P, Lopez OL, Ikram MA, Tzourio C, Lambert JC. A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly. Mol Psychiatry. 2014 Dec;19(12):1326-35.

844. Dane AD, Hendriks MM, Reijmers TH, Harms AC, Troost J, Vreeken RJ, Boomsma DI, van Duijn CM, Slagboom EP, Hankemeier T. Integrating metabolomics profiling measurements across multiple biobanks. Anal Chem. 2014 May 6;86(9):4110-4.

845. Deelen J, Beekman M, Codd V, Trompet S, Broer L, Hägg S, Fischer K, Thijssen PE, Suchiman HE, Postmus I, Uitterlinden AG, Hofman A, de Craen AJ, Metspalu A, Pedersen NL, van Duijn CM, Jukema JW, Houwing-Duistermaat JJ, Samani NJ, Slagboom PE. Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers. Int J Epidemiol. 2014 Jun;43(3):878-86.

846. Deelen J, Beekman M, Uh HW, Broer L, Ayers KL, Tan Q, Kamatani Y, Bennet AM, Tamm R, Trompet S, Guðbjartsson DF, Flachsbart F, Rose G, Viktorin A, Fischer K, Nygaard M, Cordell HJ, Crocco P, van den Akker EB, Böhringer S, Helmer Q, Nelson CP, Saunders GI, Alver M, Andersen-Ranberg K, Breen ME, van der Breggen R, Caliebe A, Capri M, Cevenini E, Collerton JC, Dato S, Davies K, Ford I, Gampe J, Garagnani P, de Geus EJ, Harrow J, van Heemst D, Heijmans BT, Heinsen FA, Hottenga JJ, Hofman A, Jeune B, Jonsson PV, Lathrop M, Lechner D, Martin-Ruiz C, Mcnerlan SE, Mihailov E, Montesanto A, Mooijaart SP, Murphy A, Nohr EA, Paternoster L, Postmus I, Rivadeneira F, Ross OA, Salvioli S, Sattar N, Schreiber S, Stefánsson H, Stott DJ, Tiemeier H, Uitterlinden AG, Westendorp RG, Willemsen G, Samani NJ, Galan P, Sørensen TI, Boomsma DI, Jukema JW, Rea IM, Passarino G, de Craen AJ, Christensen K, Nebel A, Stefánsson K, Metspalu A, Magnusson P, Blanché H, Christiansen L, Kirkwood TB, van Duijn CM, Franceschi C, Houwing-Duistermaat JJ, Slagboom PE. Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. Hum Mol Genet. 2014 Aug 15;23(16):4420-32.

847. Deelen P, Menelaou A, van Leeuwen EM, Kanterakis A, van Dijk F, Medina-Gomez C, Francioli LC, Hottenga JJ, Karssen LC, Estrada K, Kreiner-Møller E, Rivadeneira F, van Setten J, Gutierrez-Achury J, Westra HJ, Franke L, van Enckevort D, Dijkstra M, Byelas H, van Duijn CM; Genome of the Netherlands Consortium, de Bakker PI, Wijmenga C, Swertz MA; Genome of the Netherlands Consortium. Improved imputation quality of low-frequency and rare variants

in European samples using the 'Genome of The Netherlands'. Eur J Hum Genet. 2014 Nov;22(11):1321-6.

848. Dharuri H, Demirkan A, van Klinken JB, Mook-Kanamori DO, van Duijn CM, 't Hoen PA, Willems van Dijk K. Genetics of the human metabolome, what is next? Biochim Biophys Acta. 2014 Oct;1842(10):1923-1931.

849. DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium; Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium; Mexican American Type 2 Diabetes (MAT2D) Consortium; Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium, Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, Saleheen D, Wang X, Zeggini E, Abecasis GR, Adair LS, Almgren P, Atalay M, Aung T, Baldassarre D, Balkau B, Bao Y, Barnett AH, Barroso I, Basit A, Been LF, Beilby J, Bell GI, Benediktsson R, Bergman RN, Boehm BO, Boerwinkle E, Bonnycastle LL, Burtt N, Cai Q, Campbell H, Carey J, Cauchi S, Caulfield M, Chan JC, Chang LC, Chang TJ, Chang YC, Charpentier G, Chen CH, Chen H, Chen YT, Chia KS, Chidambaram M, Chines PS, Cho NH, Cho YM, Chuang LM, Collins FS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Danesh J, Das D, de Faire U, Dedoussis G, Deloukas P, Dimas AS, Dina C, Doney AS, Donnelly PJ, Dorkhan M, van Duijn C, Dupuis J, Edkins S, Elliott P, Emilsson V, Erbel R, Eriksson JG, Escobedo J, Esko T, Eury E, Florez JC, Fontanillas P, Forouhi NG, Forsen T, Fox C, Fraser RM, Frayling TM, Froguel P, Frossard P, Gao Y, Gertow K, Gieger C, Gigante B, Grallert H, Grant GB, Grrop LC, Groves CJ, Grundberg E, Guiducci C, Hamsten A, Han BG, Hara K, Hassanali N, Hattersley AT, Hayward C, Hedman AK, Herder C, Hofman A, Holmen OL, Hovingh K, Hreidarsson AB, Hu C, Hu FB, Hui J, Humphries SE, Hunt SE, Hunter DJ, Hveem K, Hydrie ZI, Ikegami H, Illig T, Ingelsson E, Islam M, Isomaa B, Jackson AU, Jafar T, James A, Jia W, Jöckel KH, Jonsson A, Jowett JB, Kadowaki T, Kang HM, Kanoni S, Kao WH, Kathiresan S, Kato N, Katulanda P, Keinanen-Kiukaanniemi KM, Kelly AM, Khan H, Khaw KT, Khor CC, Kim HL, Kim S, Kim YJ, Kinnunen L, Klopp N, Kong A, Korpi-Hyövälti E, Kowlessur S, Kraft P, Kravic J, Kristensen MM, Krithika S, Kumar A, Kumate J, Kuusisto J, Kwak SH, Laakso M, Lagou V, Lakka TA, Langenberg C, Langford C, Lawrence R, Leander K, Lee JM, Lee NR, Li M, Li X, Li Y, Liang J, Liju S, Lim WY, Lind L, Lindgren CM, Lindholm E, Liu CT, Liu JJ, Lobbens S, Long J, Loos RJ, Lu W, Luan J, Lyssenko V, Ma RC, Maeda S, Mägi R, Männisto S, Matthews DR, Meigs JB, Melander O, Metspalu A, Meyer J, Mirza G, Mihailov E, Moebus S, Mohan V, Mohlke KL, Morris AD, Mühleisen TW, Müller-Nurasyid M, Musk B, Nakamura J, Nakashima E, Navarro P, Ng PK, Nica AC, Nilsson PM, Njølstad I, Nöthen MM, Ohnaka K, Ong TH, Owen KR, Palmer CN, Pankow JS, Park KS, Parkin M, Pechlivanis S, Pedersen NL, Peltonen L, Perry JR, Peters A, Pinidiyapathirage JM, Platou CG, Potter S, Price JF, Qi L, Radha V, Rallidis L, Rasheed A, Rathman W, Rauramaa R, Raychaudhuri S, Rayner NW, Rees SD, Rehnberg E, Ripatti S, Robertson N, Roden M, Rossin EJ, Rudan I, Rybin D, Saaristo TE, Salomaa V, Saltevo J, Samuel M, Sanghera DK, Saramies J, Scott J, Scott LJ, Scott RA, Segrè AV, Sehmi J, Sennblad B, Shah N, Shah S, Shera AS, Shu XO, Shuldiner AR, Sigurđsson G, Sijbrands E, Silveira A, Sim X, Sivapalaratnam S, Small KS, So WY, Stančáková A, Stefansson K, Steinbach G, Steinthorsdottir V, Stirrups K, Strawbridge RJ, Stringham HM, Sun Q, Suo C, Syvänen AC, Takayanagi R, Takeuchi F, Tay WT, Teslovich TM, Thorand B, Thorleifsson G, Thorsteinsdottir U, Tikkanen E, Trakalo J, Tremoli E, Trip MD, Tsai FJ, Tuomi T, Tuomilehto J, Uitterlinden AG, Valladares-Salgado A, Vedantam S, Veglia F, Voight BF, Wang C, Wareham NJ, Wennauer R, Wickremasinghe AR, Wilsgaard T, Wilson JF, Wiltshire S, Winckler W, Wong TY, Wood AR, Wu JY, Wu Y, Yamamoto K, Yamauchi T, Yang M, Yengo L, Yokota M, Young R, Zabaneh D, Zhang F, Zhang R, Zheng W, Zimmet PZ, Altshuler D, Bowden DW, Cho YS, Cox NJ, Cruz M, Hanis CL, Kooner J, Lee JY, Seielstad M,

Teo YY, Boehnke M, Parra EJ, Chambers JC, Tai ES, McCarthy MI, Morris AP. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014 Mar;46(3):234-44.

850. Dijkstra AE, Smolonska J, van den Berge M, Wijmenga C, Zanen P, Luinge MA, Platteel M, Lammers JW, Dahlback M, Tosh K, Hiemstra PS, Sterk PJ, Spira A, Vestbo J, Nordestgaard BG, Benn M, Nielsen SF, Dahl M, Verschuren WM, Picavet HS, Smit HA, Owsijewitsch M, Kauczor HU, de Koning HJ, Nizankowska-Mogilnicka E, Mejza F, Nastalek P, van Diemen CC, Cho MH, Silverman EK, Crapo JD, Beaty TH, Lomas DA, Bakke P, Gulsvik A, Bossé Y, Obeidat MA, Loth DW, Lahousse L, Rivadeneira F, Uitterlinden AG, Hofman A, Stricker BH, Brusselle GG, van Duijn CM, Brouwer U, Koppelman GH, Vonk JM, Nawijn MC, Groen HJ, Timens W, Boezen HM, Postma DS; LifeLines Cohort study. Susceptibility to chronic mucus hypersecretion, a genome wide association study. PLoS One. 2014 Apr 8;9(4):e91621.

851. Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M; United Kingdom Brain Expression Consortium, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Hernández I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-García A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams J. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. PLoS One. 2014 Jun 12;9(6):e94661.

852. Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Gu X, Smith AV, Yang ML, Zhang Y, Ehret G, Rose LM, Hwang SJ, Papanicolau GJ, Sijbrands EJ, Rice K, Eiriksdottir G, Pihur V, Ridker PM, Vasan RS, Newton-Cheh C; Global Blood Pressure Genetics Consortium, Raffel LJ, Amin N, Rotter JI, Liu K, Launer LJ, Xu M, Caulfield M, Morrison AC, Johnson AD, Vaidya D, Dehghan A, Li G, Bouchard C, Harris TB, Zhang H, Boerwinkle E, Siscovick DS, Gao W, Uitterlinden AG, Rivadeneira F, Hofman A, Willer CJ, Franco OH, Huo Y, Witteman JC, Munroe PB, Gudnason V, Palmas W, van Duijn C, Fornage M, Levy D, Psaty BM, Chakravarti A. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet. 2014 Jul 3;95(1):49-65.

853. Hessel EV, de Wit M, Wolterink-Donselaar IG, Karst H, de Graaff E, van Lith HA, de Bruijn E, de Sonnaville S, Verbeek NE, Lindhout D, de Kovel CG, Koeleman BP, van Kempen M, Brilstra E, Cuppen E, Loos M, Spijker SS, Kan AA, Baars SE, van Rijen PC, Gosselaar PH, Groot Koerkamp MJ, Holstege FC, van Duijn C, Vergeer J, Moll HA, Taubøll E, Heuser K, Ramakers GM, Pasterkamp RJ, van Nieuwenhuizen O, Hoogenraad CC, Kas MJ, de Graan PN. Identification of Srp9 as a febrile seizure susceptibility gene. Ann Clin Transl Neurol. 2014 Apr;1(4):239-50.

854. Hysi PG, Cheng CY, Springelkamp H, Macgregor S, Bailey JN, Wojciechowski R, Vitart V, Nag A, Hewitt AW, Höhn R, Venturini C, Mirshahi A, Ramdas WD, Thorleifsson G, Vithana E, Khor CC, Stefansson AB, Liao J, Haines JL, Amin N, Wang YX, Wild PS, Ozel AB, Li JZ, Fleck BW, Zeller T, Staffieri SE, Teo YY, Cuellar-Partida G, Luo X, Allingham RR, Richards JE, Senft A, Karssen LC, Zheng Y, Bellenguez C, Xu L, Iglesias AI, Wilson JF, Kang JH, van Leeuwen EM, Jonsson V, Thorsteinsdottir U, Despriet DD, Ennis S, Moroi SE, Martin NG, Jansonius NM, Yazar S, Tai ES, Amouyel P, Kirwan J, van Koolwijk LM, Hauser MA, Jonasson F, Leo P, Loomis SJ, Fogarty R, Rivadeneira F, Kearns L, Lackner KJ, de Jong PT, Simpson CL, Pennell CE, Oostra BA, Uitterlinden AG, Saw SM, Lotery AJ, Bailey-Wilson JE, Hofman A, Vingerling JR, Maubaret C, Pfeiffer N, Wolfs RC, Lemij HG, Young TL, Pasquale LR, Delcourt C, Spector TD, Klaver CC, Small KS, Burdon KP, Stefansson K, Wong TY; BMES GWAS Group; NEIGHBORHOOD Consortium; Wellcome Trust Case Control Consortium 2, Viswanathan A, Mackey DA, Craig JE, Wiggs JL, van Duijn CM, Hammond CJ, Aung T. Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. Nat Genet. 2014 Oct;46(10):1126-30.

855. Ibrahim-Verbaas CA, Fornage M, Bis JC, Choi SH, Psaty BM, Meigs JB, Rao M, Nalls M, Fontes JD, O'Donnell CJ, Kathiresan S, Ehret GB, Fox CS, Malik R, Dichgans M, Schmidt H, Lahti J, Heckbert SR, Lumley T, Rice K, Rotter JI, Taylor KD, Folsom AR, Boerwinkle E, Rosamond WD, Shahar E, Gottesman RF, Koudstaal PJ, Amin N, Wieberdink RG, Dehghan A, Hofman A, Uitterlinden AG, Destefano AL, Debette S, Xue L, Beiser A, Wolf PA, Decarli C, Ikram MA, Seshadri S, Mosley TH Jr, Longstreth WT Jr, van Duijn CM, Launer LJ. Predicting stroke through genetic risk functions: the CHARGE Risk Score Project. Stroke. 2014 Feb;45(2):403-12.

856. Iglesias AI, Mihaescu R, Ioannidis JP, Khoury MJ, Little J, van Duijn CM, Janssens AC. Scientific reporting is suboptimal for aspects that characterize genetic risk prediction studies: a review of published articles based on the Genetic RIsk Prediction Studies statement. J Clin Epidemiol. 2014 May;67(5):487-99.

857. Iglesias AI, Springelkamp H, van der Linde H, Severijnen LA, Amin N, Oostra B, Kockx CE, van den Hout MC, van Ijcken WF, Hofman A, Uitterlinden AG, Verdijk RM, Klaver CC, Willemsen R, van Duijn CM. Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation-differentiation balance early in life and optic nerve degeneration at old age. Hum Mol Genet. 2014 Mar 1;23(5):1320-32.

858. Janssen SF, Gorgels TG, Ramdas WD, Klaver CC, van Duijn CM, Jansonius NM, Bergen AA. Alzheimer's disease and glaucoma-reply. Prog Retin Eye Res. 2014 Mar;39:108-10. No abstract available.

859. Keller MF, Reiner AP, Okada Y, van Rooij FJ, Johnson AD, Chen MH, Smith AV, Morris AP,

Tanaka T, Ferrucci L, Zonderman AB, Lettre G, Harris T, Garcia M, Bandinelli S, Qayyum R, Yanek LR, Becker DM, Becker LC, Kooperberg C, Keating B, Reis J, Tang H, Boerwinkle E, Kamatani Y, Matsuda K, Kamatani N, Nakamura Y, Kubo M, Liu S, Dehghan A, Felix JF, Hofman A, Uitterlinden AG, van Duijn CM, Franco OH, Longo DL, Singleton AB, Psaty BM, Evans MK, Cupples LA, Rotter JI, O'Donnell CJ, Takahashi A, Wilson JG, Ganesh SK, Nalls MA; CHARGE Hematology, COGENT, and BioBank Japan Project (RIKEN) Working Groups. Trans-ethnic meta-analysis of white blood cell phenotypes. Hum Mol Genet. 2014 Dec 20;23(25):6944-60.

860. Kruithof CJ, Kooijman MN, van Duijn CM, Franco OH, de Jongste JC, Klaver CC, Mackenbach JP, Moll HA, Raat H, Rings EH, Rivadeneira F, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, Wolvius EB, Hofman A, Jaddoe VW. The Generation R Study: Biobank update 2015. Eur J Epidemiol. 2014 Dec;29(12):911-27.

861. Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, Bizon C, Lange EM, Smith JD, Turner EH, Jun G, Kang HM, Peloso G, Auer P, Li KP, Flannick J, Zhang J, Fuchsberger C, Gaulton K, Lindgren C, Locke A, Manning A, Sim X, Rivas MA, Holmen OL, Gottesman O, Lu Y, Ruderfer D, Stahl EA, Duan Q, Li Y, Durda P, Jiao S, Isaacs A, Hofman A, Bis JC, Correa A, Griswold ME, Jakobsdottir J, Smith AV, Schreiner PJ, Feitosa MF, Zhang Q, Huffman JE, Crosby J, Wassel CL, Do R, Franceschini N, Martin LW, Robinson JG, Assimes TL, Crosslin DR, Rosenthal EA, Tsai M, Rieder MJ, Farlow DN, Folsom AR, Lumley T, Fox ER, Carlson CS, Peters U, Jackson RD, van Duijn CM, Uitterlinden AG, Levy D, Rotter JI, Taylor HA, Gudnason V Jr, Siscovick DS, Fornage M, Borecki IB, Hayward C, Rudan I, Chen YE, Bottinger EP, Loos RJ, Sætrom P, Hveem K, Boehnke M, Groop L, McCarthy M, Meitinger T, Ballantyne CM, Gabriel SB, O'Donnell CJ, Post WS, North KE, Reiner AP, Boerwinkle E, Psaty BM, Altshuler D, Kathiresan S, Lin DY, Jarvik GP, Cupples LA, Kooperberg C, Wilson JG, Nickerson DA, Abecasis GR, Rich SS, Tracy RP, Willer CJ; NHLBI Grand Opportunity Exome Sequencing Project. Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. Am J Hum Genet. 2014 Feb 6;94(2):233-45.

862. van Leeuwen EM, Smouter FA, Kam-Thong T, Karbalai N, Smith AV, Harris TB, Launer LJ, Sitlani CM, Li G, Brody JA, Bis JC, White CC, Jaiswal A, Oostra BA, Hofman A, Rivadeneira F, Uitterlinden AG, Boerwinkle E, Ballantyne CM, Gudnason V, Psaty BM, Cupples LA, Järvelin MR, Ripatti S, Isaacs A, Müller-Myhsok B, Karssen LC, van Duijn CM. The Challenges of Genome-Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels. PLoS One. 2014 Oct 20;9(10):e109290.

863. Li Q, Wojciechowski R, Simpson CL, Hysi PG, Verhoeven VJ, Ikram MK, Höhn R, Vitart V, Hewitt AW, Oexle K, Mäkelä KM, MacGregor S, Pirastu M, Fan Q, Cheng CY, St Pourcain B, McMahon G, Kemp JP, Northstone K, Rahi JS, Cumberland PM, Martin NG, Sanfilippo PG, Lu Y, Wang YX, Hayward C, Polašek O, Campbell H, Bencic G, Wright AF, Wedenoja J, Zeller T, Schillert A, Mirshahi A, Lackner K, Yip SP, Yap MK, Ried JS, Gieger C, Murgia F, Wilson JF, Fleck B, Yazar S, Vingerling JR, Hofman A, Uitterlinden A, Rivadeneira F, Amin N, Karssen L, Oostra BA, Zhou X, Teo YY, Tai ES, Vithana E, Barathi V, Zheng Y, Siantar RG, Neelam K, Shin Y, Lam J, Yonova-Doing E, Venturini C, Hosseini SM, Wong HS, Lehtimäki T, Kähönen M, Raitakari O, Timpson NJ, Evans DM, Khor CC, Aung T, Young TL, Mitchell P, Klein B, van Duijn CM, Meitinger T, Jonas JB, Baird PN, Mackey DA, Wong TY, Saw SM, Pärssinen O, Stambolian D, Hammond CJ, Klaver CC, Williams C, Paterson AD, Bailey-Wilson JE, Guggenheim JA; CREAM Consortium. Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the

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864. Ling Y, van Herpt TT, van Hoek M, Dehghan A, Hofman A, Uitterlinden AG, Jiang S, Lieverse AG, Bravenboer B, Lu D, van Duijn CM, Gao X, Sijbrands EJ. A genetic variant in SLC6A20 is associated with Type 2 diabetes in white-European and Chinese populations. Diabet Med. 2014 Nov;31(11):1350-6.

865. Liu F, Hendriks AE, Ralf A, Boot AM, Benyi E, Sävendahl L, Oostra BA, van Duijn C, Hofman A, Rivadeneira F, Uitterlinden AG, Drop SL, Kayser M. Common DNA variants predict tall stature in Europeans. Hum Genet. 2014 May;133(5):587-97.

866. Lubke GH, Laurin C, Amin N, Hottenga JJ, Willemsen G, van Grootheest G, Abdellaoui A, Karssen LC, Oostra BA, van Duijn CM, Penninx BW, Boomsma DI. Genome-wide analyses of borderline personality features. Mol Psychiatry. 2014 Aug;19(8):923-9.

867. Malik R, Bevan S, Nalls MA, Holliday EG, Devan WJ, Cheng YC, Ibrahim-Verbaas CA, Verhaaren BF, Bis JC, Joon AY, de Stefano AL, Fornage M, Psaty BM, Ikram MA, Launer LJ, van Duijn CM, Sharma P, Mitchell BD, Rosand J, Meschia JF, Levi C, Rothwell PM, Sudlow C, Markus HS, Seshadri S, Dichgans M; Wellcome Trust Case Control Consortium 2. Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies. Stroke. 2014 Feb;45(2):394-402.

868. Medway C, Combarros O, Cortina-Borja M, Butler HT, Ibrahim-Verbaas CA, de Bruijn RF, Koudstaal PJ, van Duijn CM, Ikram MA, Mateo I, Sánchez-Juan P, Lehmann MG, Heun R, Kölsch H, Deloukas P, Hammond N, Coto E, Alvarez V, Kehoe PG, Barber R, Wilcock GK, Brown K, Belbin O, Warden DR, Smith AD, Morgan K, Lehmann DJ. The sex-specific associations of the aromatase gene with Alzheimer's disease and its interaction with IL10 in the Epistasis Project. Eur J Hum Genet. 2014 Feb;22(2):216-20.

869. Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M, Isaacs A, Jakobsdottir J, Feitosa MF, Davies G, Huffman JE, Manichaikul A, Davis B, Lohman K, Joon AY, Smith AV, Grove ML, Zanoni P, Redon V, Demissie S, Lawson K, Peters U, Carlson C, Jackson RD, Ryckman KK, Mackey RH, Robinson JG, Siscovick DS, Schreiner PJ, Mychaleckyj JC, Pankow JS, Hofman A, Uitterlinden AG, Harris TB, Taylor KD, Stafford JM, Reynolds LM, Marioni RE, Dehghan A, Franco OH, Patel AP, Lu Y, Hindy G, Gottesman O, Bottinger EP, Melander O, Orho-Melander M, Loos RJ, Duga S, Merlini PA, Farrall M, Goel A, Asselta R, Girelli D, Martinelli N, Shah SH, Kraus WE, Li M, Rader DJ, Reilly MP, McPherson R, Watkins H, Ardissino D; NHLBI GO Exome Sequencing Project, Zhang Q, Wang J, Tsai MY, Taylor HA, Correa A, Griswold ME, Lange LA, Starr JM, Rudan I, Eiriksdottir G, Launer LJ, Ordovas JM, Levy D, Chen YD, Reiner AP, Hayward C, Polasek O, Deary IJ, Borecki IB, Liu Y, Gudnason V, Wilson JG, van Duijn CM, Kooperberg C, Rich SS, Psaty BM, Rotter JI, O'Donnell CJ, Rice K, Boerwinkle E, Kathiresan S, Cupples LA. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet. 2014 Feb 6;94(2):223-32.

870. Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, Franceschini N, Ganna A, Johnson AD, Kjellqvist S, Lunetta KL, McMahon G, Nolte IM, Paternoster L, Porcu E, Smith AV, Stolk L, Teumer A, Tšernikova N, Tikkanen E, Ulivi S, Wagner EK, Amin N, Bierut LJ, Byrne EM, Hottenga JJ, Koller DL, Mangino M, Pers TH, Yerges-Armstrong LM, Hua Zhao

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871. Pirastu N, Kooyman M, Traglia M, Robino A, Willems SM, Pistis G, d'Adamo P, Amin N, d'Eustacchio A, Navarini L, Sala C, Karssen LC, van Duijn C, Toniolo D, Gasparini P. Association analysis of bitter receptor genes in five isolated populations identifies a significant correlation between TAS2R43 variants and coffee liking. PLoS One. 2014 Mar 19;9(3):e92065.

872. Rietveld CA, Esko T, Davies G, Pers TH, Turley P, Benyamin B, Chabris CF, Emilsson V, Johnson AD, Lee JJ, Leeuw Cd, Marioni RE, Medland SE, Miller MB, Rostapshova O, van der Lee SJ, Vinkhuyzen AA, Amin N, Conley D, Derringer J, van Duijn CM, Fehrmann R, Franke L, Glaeser EL, Hansell NK, Hayward C, Iacono WG, Ibrahim-Verbaas C, Jaddoe V, Karjalainen J, Laibson D, Lichtenstein P, Liewald DC, Magnusson PK, Martin NG, McGue M, McMahon G, Pedersen NL, Pinker S, Porteous DJ, Posthuma D, Rivadeneira F, Smith BH, Starr JM, Tiemeier H, Timpson NJ, Trzaskowski M, Uitterlinden AG, Verhulst FC, Ward ME, Wright MJ, Davey Smith G, Deary IJ, Johannesson M, Plomin R, Visscher PM, Benjamin DJ, Cesarini D, Koellinger PD. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13790-4.

873. Ruiz A, Heilmann S, Becker T, Hernández I, Wagner H, Thelen M, Mauleón A, Rosende-Roca M, Bellenguez C, Bis JC, Harold D, Gerrish A, Sims R, Sotolongo-Grau O, Espinosa A, Alegret M, Arrieta JL, Lacour A, Leber M, Becker J, Lafuente A, Ruiz S, Vargas L, Rodríguez O, Ortega G, Dominguez MA; IGAP, Mayeux R, Haines JL, Pericak-Vance MA, Farrer LA, Schellenberg GD, Chouraki V, Launer LJ, van Duijn C, Seshadri S, Antúnez C, Breteler MM, Serrano-Ríos M, Jessen F, Tárraga L, Nöthen MM, Maier W, Boada M, Ramírez A. Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene. Transl Psychiatry. 2014 Feb 4;4:e358.

874. Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, Corre T, de Boer RA, Goel A, Johnson T, Khor CC; LifeLines Cohort Study, Lluís-Ganella C, Luan J, Lyytikäinen LP, Nolte IM, Sim X, Sõber S, van der Most PJ, Verweij N, Zhao JH, Amin N, Boerwinkle E, Bouchard C, Dehghan A, Eiriksdottir G, Elosua R, Franco OH, Gieger C, Harris TB, Hercberg S, Hofman A, James AL, Johnson AD, Kähönen M, Khaw KT, Kutalik Z, Larson MG, Launer LJ, Li G, Liu J, Liu K, Morrison AC, Navis G, Ong RT, Papanicolau GJ, Penninx BW, Psaty BM, Raffel LJ, Raitakari OT, Rice K, Rivadeneira F, Rose LM, Sanna S, Scott RA, Siscovick DS, Stolk RP, Uitterlinden AG, Vaidya D, van der Klauw MM, Vasan RS, Vithana EN, Völker U, Völzke H, Watkins H, Young TL, Aung T, Bochud M, Farrall M, Hartman CA, Laan M, Lakatta EG, Lehtimäki T, Loos RJ, Lucas G, Meneton P, Palmer LJ, Rettig R, Snieder H, Tai ES, Teo YY, van der Harst P, Wareham NJ, Wijmenga C, Wong TY, Fornage M, Gudnason V, Levy D, Palmas W, Ridker PM, Rotter JI, van Duijn CM, Witteman JC, Chakravarti A, Rao DC. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. Am J Hum Genet. 2014 Jul 3;95(1):24-38.

875. Simpson CL, Wojciechowski R, Oexle K, Murgia F, Portas L, Li X, Verhoeven VJ, Vitart V, Schache M, Hosseini SM, Hysi PG, Raffel LJ, Cotch MF, Chew E, Klein BE, Klein R, Wong TY, van Duijn CM, Mitchell P, Saw SM, Fossarello M, Wang JJ; DCCT/EDIC Research Group, Polašek O, Campbell H, Rudan I, Oostra BA, Uitterlinden AG, Hofman A, Rivadeneira F, Amin N, Karssen LC, Vingerling JR, Döring A, Bettecken T, Bencic G, Gieger C, Wichmann HE, Wilson JF, Venturini C, Fleck B, Cumberland PM, Rahi JS, Hammond CJ, Hayward C, Wright AF, Paterson AD, Baird PN, Klaver CC, Rotter JI, Pirastu M, Meitinger T, Bailey-Wilson JE, Stambolian D. Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 Loci. PLoS One. 2014 Sep 18;9(9):e107110.

876. Springelkamp H, Höhn R, Mishra A, Hysi PG, Khor CC, Loomis SJ, Bailey JN, Gibson J, Thorleifsson G, Janssen SF, Luo X, Ramdas WD, Vithana E, Nongpiur ME, Montgomery GW, Xu L, Mountain JE, Gharahkhani P, Lu Y, Amin N, Karssen LC, Sim KS, van Leeuwen EM, Iglesias AI, Verhoeven VJ, Hauser MA, Loon SC, Despriet DD, Nag A, Venturini C, Sanfilippo PG, Schillert A, Kang JH, Landers J, Jonasson F, Cree AJ, van Koolwijk LM, Rivadeneira F, Souzeau E, Jonsson V, Menon G; Blue Mountains Eye Study—GWAS group, Weinreb RN, de Jong PT, Oostra BA, Uitterlinden AG, Hofman A, Ennis S, Thorsteinsdottir U, Burdon KP; NEIGHBORHOOD Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2), Spector TD, Mirshahi A, Saw SM, Vingerling JR, Teo YY, Haines JL, Wolfs RC, Lemij HG, Tai ES, Jansonius NM, Jonas JB, Cheng CY, Aung T, Viswanathan AC, Klaver CC, Craig JE, Macgregor S, Mackey DA, Lotery AJ, Stefansson K, Bergen AA, Young TL, Wiggs JL, Pfeiffer N, Wong TY, Pasquale LR, Hewitt AW, van Duijn CM, Hammond CJ; Blue Mountains Eye Study-GWAS group; NEIGHBORHOOD Consortium; Wellcome Trust Case Control Consortium 2 WTCCC2. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process. Nat Commun. 2014 Sep 22;5:4883.

877. Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T, Holmes MV, Padmanabhan S, Karczewski KJ, Almoguera B, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Gaunt TR, Gho JM, Gieger C, Goel A, Gong Y, Isaacs A, Kleber ME, Mateo Leach I, McDonough CW, Meijs MF, Melander O, Nelson CP, Nolte IM, Pankratz N, Price TS, Shaffer J, Shah S, Tomaszewski M, van der Most PJ, Van Iperen EP, Vonk JM, Witkowska K, Wong CO, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Brown M, Burt A, Cooper-DeHoff RM, Connell JM, Cruickshanks KJ, Curtis SP, Davey-Smith G, Delles C,

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878. Vaarhorst AA, Verhoeven A, Weller CM, Böhringer S, Göraler S, Meissner A, Deelder AM, Henneman P, Gorgels AP, van den Brandt PA, Schouten LJ, van Greevenbroek MM, Merry AH, Verschuren WM, van den Maagdenberg AM, van Dijk KW, Isaacs A, Boomsma D, Oostra BA, van Duijn CM, Jukema JW, Boer JM, Feskens E, Heijmans BT, Slagboom PE. A metabolomic profile is associated with the risk of incident coronary heart disease. Am Heart J. 2014 Jul;168(1):45-52.e7.

879. van der Valk RJ, Duijts L, Timpson NJ, Salam MT, Standl M, Curtin JA, Genuneit J, Kerhof M, Kreiner-Møller E, Cáceres A, Gref A, Liang LL, Taal HR, Bouzigon E, Demenais F, Nadif R, Ober C, Thompson EE, Estrada K, Hofman A, Uitterlinden AG, van Duijn C, Rivadeneira F, Li X, Eckel SP, Berhane K, Gauderman WJ, Granell R, Evans DM, St Pourcain B, McArdle W, Kemp JP, Smith GD, Tiesler CM, Flexeder C, Simpson A, Murray CS, Fuchs O, Postma DS, Bønnelykke K, Torrent M, Andersson M, Sleiman P, Hakonarson H, Cookson WO, Moffatt MF, Paternoster L, Melén E, Sunyer J, Bisgaard H, Koppelman GH, Ege M, Custovic A, Heinrich J, Gilliland FD, Henderson AJ, Jaddoe VW, de Jongste JC; EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium. Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. J Allergy Clin Immunol. 2014 Jul;134(1):46-55.

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883. Verwoert GC, Hofland J, Amin N, Mattace-Raso FU, Sijbrands EJ, Hofman A, van den Meiracker AH, Uitterlinden AG, van Duijn CM, de Jong FH, Danser AH. Expression and Gene Variation Studies Deny Association of Human HSD3B1 Gene With Aldosterone Production or Blood Pressure. Am J Hypertens. 2015 Jan;28(1):113-20.

884. Wang JJ, Buitendijk GH, Rochtchina E, Lee KE, Klein BE, van Duijn CM, Flood VM, Meuer SM, Attia J, Myers C, Holliday EG, Tan AG, Smith WT, Iyengar SK, de Jong PT, Hofman A, Vingerling JR, Mitchell P, Klein R, Klaver CC. Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations. Ophthalmology. 2014 Mar;121(3):667-75.

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2015

886. Adams HH, de Bruijn RF, Hofman A, Uitterlinden AG, van Duijn CM, Vernooij MW, Koudstaal PJ, Ikram MA. Genetic risk of neurodegenerative diseases is associated with mild cognitive impairment and conversion to dementia. Alzheimers Dement. 2015;11(11):1277-85.

887. Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA, Orwoll ES, Parimi N, Psaty BM, Rivadeneira F, Rotter JI, Seshadri S, Singleton A, Tiemeier H, Uitterlinden AG, Zhao

W, Bandinelli S, Bennett DA, Ferrucci L, Gudnason V, Harris TB, Karasik D, Launer LJ, Perls TT, Slagboom PE, Tranah GJ, Weir DR, Newman AB, van Duijn CM, Murabito JM. Gwas of longevity in charge consortium confirms apoe and foxo3 candidacy. J Gerontol A Biol Sci Med Sci. 2015;70(1):110-8.

888. Broer L, van Duijn CM. Gwas and meta-analysis in aging/longevity. Adv Exp Med Biol. 2015;847:107-25.

889. Chauhan G, Adams HH, Bis JC, Weinstein G, Yu L, Toglhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikanth V, Knopman DS, Jack CR, Jr., Amouyel P, Hofman A, DeCarli C, Tzourio C, van Duijn CM, Bennett DA, Schmidt R, Longstreth WT, Jr., Mosley TH, Fornage M, Launer LJ, Seshadri S, Ikram MA, Debette S. Association of alzheimer's disease gwas loci with mri markers of brain aging. Neurobiol Aging. 2015;36(4):1765 e7-16.

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892. Cuellar-Partida G, Springelkamp H, Lucas SE, Yazar S, Hewitt AW, Iglesias AI, Montgomery GW, Martin NG, Pennell CE, van Leeuwen EM, Verhoeven VJ, Hofman A, Uitterlinden AG, Ramdas WD, Wolfs RC, Vingerling JR, Brown MA, Mills RA, Craig JE, Klaver CC, van Duijn CM, Burdon KP, MacGregor S, Mackey DA. Wnt10a exonic variant increases the risk of

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919. van Leeuwen EM, Karssen LC, Deelen J, Isaacs A, Medina-Gomez C, Mbarek H, Kanterakis A, Trompet S, Postmus I, Verweij N, van Enckevort DJ, Huffman JE, White CC, Feitosa MF, Bartz TM, Manichaikul A, Joshi PK, Peloso GM, Deelen P, van Dijk F, Willemsen G, de Geus EJ, Milaneschi Y, Penninx BW, Francioli LC, Menelaou A, Pulit SL, Rivadeneira F, Hofman A, Oostra BA, Franco OH, Mateo Leach I, Beekman M, de Craen AJ, Uh HW, Trochet H, Hocking LJ, Porteous DJ, Sattar N, Packard CJ, Buckley BM, Brody JA, Bis JC, Rotter JI, Mychaleckyj JC, Campbell H, Duan Q, Lange LA, Wilson JF, Hayward C, Polasek O, Vitart V, Rudan I, Wright AF, Rich SS, Psaty BM, Borecki IB, Kearney PM, Stott DJ, Adrienne Cupples L, Genome of the Netherlands C, Jukema JW, van der Harst P, Sijbrands EJ, Hottenga JJ, Uitterlinden AG, Swertz MA, van Ommen GJ, de Bakker PI, Eline Slagboom P, Boomsma DI, Wijmenga C, van Duijn CM. Genome of the netherlands population-specific imputations identify an abca6 variant associated with cholesterol levels. Nat Commun. 2015;6:6065.

920. Li Q, Wojciechowski R, Simpson CL, Hysi PG, Verhoeven VJ, Ikram MK, Hohn R, Vitart V, Hewitt AW, Oexle K, Makela KM, MacGregor S, Pirastu M, Fan Q, Cheng CY, St Pourcain B, McMahon G, Kemp JP, Northstone K, Rahi JS, Cumberland PM, Martin NG, Sanfilippo PG, Lu Y, Wang YX, Hayward C, Polasek O, Campbell H, Bencic G, Wright AF, Wedenoja J, Zeller T, Schillert A, Mirshahi A, Lackner K, Yip SP, Yap MK, Ried JS, Gieger C, Murgia F, Wilson JF, Fleck B, Yazar S, Vingerling JR, Hofman A, Uitterlinden A, Rivadeneira F, Amin N, Karssen L, Oostra BA, Zhou X, Teo YY, Tai ES, Vithana E, Barathi V, Zheng Y, Siantar RG, Neelam K, Shin Y, Lam J, Yonova-Doing E, Venturini C, Hosseini SM, Wong HS, Lehtimaki T, Kahonen M, Raitakari O, Timpson NJ, Evans DM, Khor CC, Aung T, Young TL, Mitchell P, Klein B, van Duijn CM, Meitinger T, Jonas JB, Baird PN, Mackey DA, Wong TY, Saw SM, Parssinen O, Stambolian D, Hammond CJ, Klaver CC, Williams C, Paterson AD, Bailey-Wilson JE, Guggenheim JA, Consortium C. Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: The cream consortium. Hum Genet. 2015;134(2):131-46.

921. Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan J, Magi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, Faul JD, Smith JA, Hua Zhao J, Zhao W, Chen J, Fehrmann R, Hedman AK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton JL, Bragg-Gresham JL, Buyske S, Demirkan A, Deng G, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Mateo Leach I, Medina-Gomez C, Medland SE, Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D, Stancakova A, Strawbridge RJ, Ju Sung Y, Tanaka T, Teumer A, Trompet S, van der Laan SW,

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922. Louter MA, Fernandez-Morales J, de Vries B, Winsvold B, Anttila V, Fernandez-Cadenas I, Vila-Pueyo M, Sintas C, van Duijn CM, Cormand B, Alvarez-Sabin J, Montaner J, Ferrari MD, van den Maagdenberg A, Palotie A, Zwart JA, Macaya A, Terwindt GM, Pozo-Rosich P. Candidate-gene association study searching for genetic factors involved in migraine chronification. Cephalalgia. 2015;35(6):500-7.

923. Maat P, de Beukelaar JW, Jansen C, Schuur M, van Duijn CM, van Coevorden MH, de Graaff E, Titulaer M, Rozemuller AJ, Sillevis Smitt P. Pathologically confirmed autoimmune encephalitis in suspected creutzfeldt-jakob disease. Neurol Neuroimmunol Neuroinflamm. 2015;2(6):e178.

924. Malik R, Freilinger T, Winsvold BS, Anttila V, Vander Heiden J, Traylor M, de Vries B, Holliday EG, Terwindt GM, Sturm J, Bis JC, Hopewell JC, Ferrari MD, Rannikmae K, Wessman M, Kallela M, Kubisch C, Fornage M, Meschia JF, Lehtimaki T, Sudlow C, Clarke R, Chasman DI, Mitchell BD, Maguire J, Kaprio J, Farrall M, Raitakari OT, Kurth T, Ikram MA, Reiner AP, Longstreth WT, Jr., Rothwell PM, Strachan DP, Sharma P, Seshadri S, Quaye L, Cherkas L, Schurks M, Rosand J, Ligthart L, Boncoraglio GB, Davey Smith G, van Duijn CM, Stefansson K, Worrall BB, Nyholt DR, Markus HS, van den Maagdenberg AM, Cotsapas C, Zwart JA, Palotie A, International Headache Genetics C, Dichgans M, Consortium MCotISG. Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants. Neurology. 2015;84(21):2132-45.

925. Medina-Gomez C, Felix JF, Estrada K, Peters MJ, Herrera L, Kruithof CJ, Duijts L, Hofman A, van Duijn CM, Uitterlinden AG, Jaddoe VW, Rivadeneira F. Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: The generation r study. Eur J Epidemiol. 2015;30(4):317-30.

926. Nalls MA, Bras J, Hernandez DG, Keller MF, Majounie E, Renton AE, Saad M, Jansen I, Guerreiro R, Lubbe S, Plagnol V, Gibbs JR, Schulte C, Pankratz N, Sutherland M, Bertram L, Lill CM, DeStefano AL, Faroud T, Eriksson N, Tung JY, Edsall C, Nichols N, Brooks J, Arepalli S, Pliner H, Letson C, Heutink P, Martinez M, Gasser T, Traynor BJ, Wood N, Hardy J, Singleton AB, International Parkinson's Disease Genomics C, Parkinson's Disease meta-analysis c. Neurox, a fast and efficient genotyping platform for investigation of neurodegenerative diseases. Neurobiol Aging. 2015;36(3):1605 e7-12.

927. Naude PJ, Dekker AD, Coppus AM, Vermeiren Y, Eisel UL, van Duijn CM, Van Dam D, De Deyn PP. Serum ngal is associated with distinct plasma amyloid-beta peptides according to the clinical diagnosis of dementia in down syndrome. J Alzheimers Dis. 2015;45(3):733-43.

928. Nyholt DR, International Headache Genetics C, Anttila V, Winsvold BS, Kurth T, Stefansson H, Kallela M, Malik R, Vries B, Terwindt GM, Ikram MA, Stam AH, Ligthart L, Freilinger T, Alexander M, Muller-Myhsok B, Schreiber S, Meitinger T, Aromaa A, Eriksson JG, Kaprio J, Boomsma DI, Duijn C, Raitakari O, Jarvelin MR, Zwart JA, Quaye L, Strachan DP, Kubisch C,

Ferrari MD, van den Maagdenberg AM, Dichgans M, Wessman M, Smith GD, Stefansson K, Chasman DI, Palotie A. Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies. Cephalalgia. 2015;35(6):489-99.

929. Pers TH, Karjalainen JM, Chan Y, Westra HJ, Wood AR, Yang J, Lui JC, Vedantam S, Gustafsson S, Esko T, Frayling T, Speliotes EK, Genetic Investigation of ATC, Boehnke M, Raychaudhuri S, Fehrmann RS, Hirschhorn JN, Franke L. Biological interpretation of genome-wide association studies using predicted gene functions. Nat Commun. 2015;6:5890.

930. Peymani A, Adams HH, Cremers LG, Krestin G, Hofman A, van Duijn CM, Uitterlinden AG, van der Lugt A, Vernooij MW, Ikram MA. Genetic determinants of unruptured intracranial aneurysms in the general population. Stroke. 2015;46(10):2961-4.

931. Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, de Geus EJ, Hemani G, Hottenga JJ, Kloiber S, Levinson DF, Lucae S, Major Depressive Disorder Working Group of the Psychiatric GC, Martin NG, Medland SE, Metspalu A, Milani L, Noethen MM, Potash JB, Rietschel M, Rietveld CA, Ripke S, Shi J, Social Science Genetic Association C, Willemsen G, Zhu Z, Boomsma DI, Wray NR, Penninx BW, Major Depressive Disorder Working Group of the Psychiatric GCCC, Social Science Genetic Association Consortium Corporate C. The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects. Mol Psychiatry. 2015;20(6):735-43.

932. Pirastu N, Kooyman M, Traglia M, Robino A, Willems SM, Pistis G, Amin N, Sala C, Karssen LC, van Duijn CM, Toniolo D, Gasparini P. Genome-wide association analysis on five isolated populations identifies variants of the hla-doa gene associated with white wine liking. Eur J Hum Genet. 2015;23(12):1717-22.

933. Plompen EP, Hansen BE, Schouten JN, Darwish Murad S, Loth DW, Brouwer WP, Isaacs A, Taimr P, Hofman A, van Duijn CM, Uitterlinden AG, Stricker BH, Leebeek FW, Janssen HL. Interferon gamma receptor 2 gene variants are associated with liver fibrosis in the general population: The rotterdam study. Gut. 2015;64(4):692-4.

934. Reinthaler EM, Dejanovic B, Lal D, Semtner M, Merkler Y, Reinhold A, Pittrich DA, Hotzy C, Feucht M, Steinbock H, Gruber-Sedlmayr U, Ronen GM, Neophytou B, Geldner J, Haberlandt E, Muhle H, Ikram MA, van Duijn CM, Uitterlinden AG, Hofman A, Altmuller J, Kawalia A, Toliat MR, Euro EC, Nurnberg P, Lerche H, Nothnagel M, Thiele H, Sander T, Meier JC, Schwarz G, Neubauer BA, Zimprich F. Rare variants in gamma-aminobutyric acid type a receptor genes in rolandic epilepsy and related syndromes. Ann Neurol. 2015;77(6):972-86.

935. Sanders YV, van der Bom JG, Isaacs A, Cnossen MH, de Maat MP, Laros-van Gorkom BA, Fijnvandraat K, Meijer K, van Duijn CM, Mauser-Bunschoten EP, Eikenboom J, Leebeek FW, Wi NSG. Clec4m and stxbp5 gene variations contribute to von willebrand factor level variation in von willebrand disease. J Thromb Haemost. 2015;13(6):956-66.

936. Shah S, Bonder MJ, Marioni RE, Zhu Z, McRae AF, Zhernakova A, Harris SE, Liewald D, Henders AK, Mendelson MM, Liu C, Joehanes R, Liang L, Consortium B, Levy D, Martin NG, Starr JM, Wijmenga C, Wray NR, Yang J, Montgomery GW, Franke L, Deary IJ, Visscher PM. Improving phenotypic prediction by combining genetic and epigenetic associations. Am J Hum Genet. 2015;97(1):75-85.

937. Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Magi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR, Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR, Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB, Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M, Mateo Leach I, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Stancakova A, Ju Sung Y, Tanaka T, Teumer A, Van Vliet-Ostaptchouk JV, Yengo L, Zhang W, Albrecht E, Arnlov J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Bluher M, Bohringer S, Bonnet F, Bottcher Y, Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E, Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Grassler J, Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heikkila K, Herzig KH, Helmer Q, Hillege HL, Holmen O, Hunt SC, Isaacs A, Ittermann T, James AL, Johansson I, Juliusdottir T, Kalafati IP, Kinnunen L, Koenig W, Kooner IK, Kratzer W, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindstrom J, Lobbens S, Lorentzon M, Mach F, Magnusson PK, Mahajan A, McArdle WL, Menni C, Merger S, Mihailov E, Milani L, Mills R, Moayyeri A, Monda KL, Mooijaart SP, Muhleisen TW, Mulas A, Muller G, Muller-Nurasyid M, Nagaraja R, Nalls MA, Narisu N, Glorioso N, Nolte IM, Olden M, Rayner NW, Renstrom F, Ried JS, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Sennblad B, Seufferlein T, Sitlani CM, Vernon Smith A, Stirrups K, Stringham HM, Sundstrom J, Swertz MA, Swift AJ, Syvanen AC, Tayo BO, Thorand B, Thorleifsson G, Tomaschitz A, Troffa C, van Oort FV, Verweij N, Vonk JM, Waite LL, Wennauer R, Wilsgaard T, Wojczynski MK, Wong A, Zhang Q, Hua Zhao J, Brennan EP, Choi M, Eriksson P, Folkersen L, Franco-Cereceda A, Gharavi AG, Hedman AK, Hivert MF, Huang J, Kanoni S, Karpe F, Keildson S, Kiryluk K, Liang L, Lifton RP, Ma B, McKnight AJ, McPherson R, Metspalu A, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Olsson C, Perry JR, Reinmaa E, Salem RM, Sandholm N, Schadt EE, Scott RA, Stolk L, Vallejo EE, Westra HJ, Zondervan KT, Consortium AD, Consortium CAD, Consortium CK, Consortium G, Consortium G, Glgc, Icbp, International Endogene C, LifeLines Cohort S, Investigators M, Mu TC, Consortium P, ReproGen C, Amouyel P, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Blangero J, Brown MJ, Burnier M, Campbell H, Chakravarti A, Chines PS, Claudi-Boehm S, Collins FS, Crawford DC, Danesh J, de Faire U, de Geus EJ, Dorr M, Erbel R, Eriksson JG, Farrall M, Ferrannini E, Ferrieres J, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gieger C, Gudnason V, Haiman CA, Harris TB, Hattersley AT, Heliovaara M, Hicks AA, Hingorani AD, Hoffmann W, Hofman A, Homuth G, Humphries SE, Hypponen E, Illig T, Jarvelin MR, Johansen B, Jousilahti P, Jula AM, Kaprio J, Kee F, Keinanen-Kiukaanniemi SM, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimaki T, Lyssenko V, Mannisto S, Marette A, Matise TC, McKenzie CA, McKnight B, Musk AW, Mohlenkamp S, Morris AD, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Palmer LJ, Penninx BW, Peters A, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ridker PM, Ritchie MD, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Shuldiner AR, Staessen JA, Steinthorsdottir V, Stolk RP, Strauch K, Tonjes A, Tremblay A, Tremoli E, Vohl MC, Volker U, Vollenweider P, Wilson JF, Witteman JC, Adair LS, Bochud M, Boehm BO, Bornstein SR, Bouchard C, Cauchi S, Caulfield MJ, Chambers JC, Chasman DI, Cooper RS, Dedoussis G, Ferrucci L, Froguel P, Grabe HJ, Hamsten A, Hui J, Hveem K, Jockel KH, Kivimaki M, Kuh D, Laakso M, Liu Y, Marz W, Munroe PB, Njolstad I, Oostra BA, Palmer CN, Pedersen NL, Perola M, Perusse L, Peters U, Power C, Quertermous T, Rauramaa R, Rivadeneira F, Saaristo TE, Saleheen D, Sinisalo J, Slagboom PE, Snieder H, Spector TD, Thorsteinsdottir U, Stumvoll M, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Veronesi G, Walker M, Wareham NJ, Watkins H,

Wichmann HE, Abecasis GR, Assimes TL, Berndt SI, Boehnke M, Borecki IB, Deloukas P, Franke L, Frayling TM, Groop LC, Hunter DJ, Kaplan RC, O'Connell JR, Qi L, Schlessinger D, Strachan DP, Stefansson K, van Duijn CM, Willer CJ, Visscher PM, Yang J, Hirschhorn JN, Zillikens MC, McCarthy MI, Speliotes EK, North KE, Fox CS, Barroso I, Franks PW, Ingelsson E, Heid IM, Loos RJ, Cupples LA, Morris AP, Lindgren CM, Mohlke KL. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015;518(7538):187-96.

938. Silva CT, Kors JA, Amin N, Dehghan A, Witteman JC, Willemsen R, Oostra BA, van Duijn CM, Isaacs A. Heritabilities, proportions of heritabilities explained by gwas findings, and implications of cross-phenotype effects on pr interval. Hum Genet. 2015;134(11-12):1211-9.

939. Springelkamp H, Iglesias AI, Cuellar-Partida G, Amin N, Burdon KP, van Leeuwen EM, Gharahkhani P, Mishra A, van der Lee SJ, Hewitt AW, Rivadeneira F, Viswanathan AC, Wolfs RC, Martin NG, Ramdas WD, van Koolwijk LM, Pennell CE, Vingerling JR, Mountain JE, Uitterlinden AG, Hofman A, Mitchell P, Lemij HG, Wang JJ, Klaver CC, Mackey DA, Craig JE, van Duijn CM, MacGregor S. Arhgef12 influences the risk of glaucoma by increasing intraocular pressure. Hum Mol Genet. 2015;24(9):2689-99.

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944. Verwoert GC, Hofland J, Amin N, Mattace-Raso FU, Sijbrands EJ, Hofman A, van den Meiracker AH, Uitterlinden AG, van Duijn CM, de Jong FH, Danser AH. Expression and gene variation studies deny association of human hsd3b1 gene with aldosterone production or blood pressure. Am J Hypertens. 2015;28(1):113-20.

945. Vojinovic D, Adams HH, van der Lee SJ, Ibrahim-Verbaas CA, Brouwer R, van den Hout MC, Oole E, van Rooij J, Uitterlinden A, Hofman A, van IWF, Aartsma-Rus A, van Ommen GB, Ikram MA, van Duijn CM, Amin N. The dystrophin gene and cognitive function in the general population. Eur J Hum Genet. 2015;23(6):837-43.

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2016

952. Adams HH, Ikram MA, Vernooij MW, van Dijk AC, Hofman A, Uitterlinden AG, van Duijn CM, Koudstaal PJ, Franco OH, van der Lugt A, Bos D. Heritability and Genome-Wide Association Analyses of Intracranial Carotid Artery Calcification: The Rotterdam Study. Stroke. 2016 47(4):912-7.

953. Akoudad S, Ikram MA, Portegies ML, Adams HH, Bos D, Hofman A, Koudstaal PJ, Uitterlinden AG, van der Lugt A, van Duijn CM, Vernooij MW. Genetic loci for serum lipid fractions and intracerebral hemorrhage. Atherosclerosis. 2016; 246:287-92.

954. Eising E, Huisman SM, Mahfouz A, Vijfhuizen LS, Anttila V, Winsvold BS, Kurth T, Ikram MA, Freilinger T, Kaprio J, Boomsma DI, van Duijn CM, Järvelin MR, Zwart JA, Quaye L, Strachan DP, Kubisch C, Dichgans M, Davey Smith G, Stefansson K, Palotie A, Chasman DI, Ferrari MD, Terwindt GM, de Vries B, Nyholt DR, Lelieveldt BP, van den Maagdenberg AM, Reinders MJ. Gene co-expression analysis identifies brain regions and cell types involved in migraine pathophysiology: a GWAS-based study using the Allen Human Brain Atlas.Hum Genet. 2016;135(4):425-39.

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956. Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL, Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl HP, Bala E, Lee KE, Hunter DJ, Sardell RJ, Mitchell P, Merriam JE, Cipriani V, Hoffman JD, Schick T, Lechanteur YT, Guymer RH, Johnson MP, Jiang Y, Stanton CM, Buitendijk GH, Zhan X, Kwong AM, Boleda A, Brooks M, Gieser L, Ratnapriya R, Branham KE, Foerster JR, Heckenlively JR, Othman MI, Vote BJ, Liang HH, Souzeau E, McAllister IL, Isaacs T, Hall J, Lake S, Mackey DA, Constable IJ, Craig JE, Kitchner TE, Yang Z, Su Z, Luo H, Chen D, Ouyang H, Flagg K, Lin D, Mao G, Ferreyra H, Stark K, von Strachwitz CN, Wolf A, Brandl C, Rudolph G, Olden M, Morrison MA, Morgan DJ, Schu M, Ahn J, Silvestri G, Tsironi EE, Park KH, Farrer LA, Orlin A, Brucker A, Li M, Curcio CA, Mohand-Saïd S, Sahel JA, Audo I, Benchaboune M, Cree AJ, Rennie CA, Goverdhan SV, Grunin M, Hagbi-Levi S, Campochiaro P, Katsanis N, Holz FG, Blond F, Blanché H, Deleuze JF, Igo RP Jr, Truitt B, Peachey NS, Meuer SM, Myers CE, Moore EL, Klein R, Hauser MA, Postel EA, Courtenay MD, Schwartz SG, Kovach JL, Scott WK, Liew G, Tan AG, Gopinath B, Merriam JC, Smith RT, Khan JC, Shahid H, Moore AT, McGrath JA, Laux R, Brantley MA Jr, Agarwal A, Ersoy L, Caramoy A, Langmann T, Saksens NT, de Jong EK, Hoyng CB, Cain MS, Richardson AJ, Martin TM, Blangero J, Weeks DE, Dhillon B, van Duijn CM, Doheny KF, Romm J, Klaver CC, Hayward C, Gorin MB, Klein ML, Baird PN, den Hollander AI, Fauser S, Yates JR, Allikmets R, Wang JJ, Schaumberg DA, Klein BE, Hagstrom SA, Chowers I, Lotery AJ, Léveillard T, Zhang K, Brilliant MH, Hewitt AW, Swaroop A, Chew EY, Pericak-Vance MA, DeAngelis M, Stambolian D, Haines JL, Iyengar SK, Weber BH, Abecasis GR, Heid IM. A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nat Genet. 2016; 48(2):134-43.

957. Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ, Schmidt CO, Mather KA, Chouraki V, Sun Q, Resnick SM, Rose LM, Oldmeadow C, Stewart M, Smith BH, Gudnason V, Yang Q, Mirza SS, Jukema JW, deJager PL, Harris TB, Liewald DC, Amin N, Coker LH, Stegle O, Lopez OL, Schmidt R, Teumer A, Ford I, Karbalai N, Becker JT, Jonsdottir MK, Au R, Fehrmann RS, Herms S, Nalls M, Zhao W, Turner ST, Yaffe K, Lohman K, van Swieten JC,

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958. Jensen RA, Sim X, Smith AV, Li X, Jakobsdóttir J, Cheng CY, Brody JA, Cotch MF, Mcknight B, Klein R, Wang JJ, Kifley A, Harris TB, Launer LJ, Taylor KD, Klein BE, Raffel LJ, Li X, Ikram MA, Klaver CC, van der Lee SJ, Mutlu U, Hofman A, Uitterlinden AG, Liu C, Kraja AT; CHARGE Exome Chip Blood Pressure Consortium, Mitchell P, Gudnason V, Rotter JI, Boerwinkle E, van Duijn CM, Psaty BM, Wong TY. Novel Genetic Loci Associated With Retinal Microvascular Diameter. Circ Cardiovasc Genet. 2016;9(1):45-54.

959. Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH Jr, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L; IGAP Consortium, Haines JL, Psaty BM, Van Broeckhoven C, Holmans P, Launer LJ, Mayeux R, Lathrop M, Goate AM, Escott-Price V, Seshadri S, Pericak-Vance MA, Amouyel P, Williams J, van Duijn CM, Schellenberg GD, Farrer LA. A novel Alzheimer disease locus located near the gene encoding tau protein. Mol Psychiatry. 2016;21(1):108-17.

960. Kettunen J, Demirkan A, Würtz P, Draisma HH, Haller T, Rawal R, Vaarhorst A, Kangas AJ, Lyytikäinen LP, Pirinen M, Pool R, Sarin AP, Soininen P, Tukiainen T, Wang Q, Tiainen M, Tynkkynen T, Amin N, Zeller T, Beekman M, Deelen J, van Dijk KW, Esko T, Hottenga JJ, van Leeuwen EM, Lehtimäki T, Mihailov E, Rose RJ, de Craen AJ, Gieger C, Kähönen M, Perola M, Blankenberg S, Savolainen MJ, Verhoeven A, Viikari J, Willemsen G, Boomsma DI, van Duijn CM, Eriksson J, Jula A, Järvelin MR, Kaprio J, Metspalu A, Raitakari O, Salomaa V, Slagboom PE, Waldenberger M, Ripatti S, Ala-Korpela M. Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA. Nat Commun. 2016; 23;7:11122.

961. Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen LP, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Greco M FD, Pasko D, Renström F, Willems SM, Mahajan A, Rose LM, Guo X, Liu Y, Kleber ME, Pérusse L, Gaunt T, Ahluwalia TS, Ju Sung Y, Ramos YF, Amin N, Amuzu A, Barroso I,

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962. Lal D, Reinthaler EM, Dejanovic B, May P, Thiele H, Lehesjoki AE, Schwarz G, Riesch E, Ikram MA, Duijn CM, Uitterlinden AG, Hofman A, Steinböck H, Gruber-Sedlmayr U, Neophytou B, Zara F, Hahn A; Genetic Commission of the Italian League against Epilepsy; EuroEPINOMICS CoGIE Consortium, Gormley P, Becker F, Weber YG, Cilio MR, Kunz WS, Krause R, Zimprich F, Lemke JR, Nürnberg P, Sander T, Lerche H, Neubauer BA. Evaluation of Presumably Disease Causing SCN1A Variants in a Cohort of Common Epilepsy Syndromes.PLoS One. 2016;18;11(3):e0150426.

963. Li M, Rothwell R, Vermaat M, Wachsmuth M, Schröder R, Laros JF, van Oven M, de Bakker PI, Bovenberg JA, van Duijn CM, van Ommen GJ, Slagboom PE, Swertz MA, Wijmenga C; Genome of the Netherlands Consortium, Kayser M, Boomsma DI, Zöllner S, de Knijff P, Stoneking M. Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck. Genome Res. 2016;26(4):417-26. Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z, Drong AW, Esko T, Evans DM, Falchi M, Feitosa MF, Ferreira T, Hedman ÅK, Haring R, Hysi PG, Iles MM, Justice AE, Kanoni S, Lagou V, Li R, Li X, Locke A, Lu C, Mägi R, Perry JR, Pers TH, Qi Q, Sanna M, Schmidt EM, Scott WR, Shungin D, Teumer A, Vinkhuyzen AA, Walker RW, Westra HJ, Zhang M, Zhang W, Zhao JH, Zhu Z, Afzal U, Ahluwalia TS, Bakker SJ, Bellis C, Bonnefond A, Borodulin K, Buchman AS, Cederholm T, Choh AC, Choi HJ, Curran JE, de Groot LC, De Jager PL, Dhonukshe-Rutten RA, Enneman AW, Eury E, Evans DS, Forsen T, Friedrich N, Fumeron F, Garcia ME, Gärtner S, Han BG, Havulinna AS, Hayward C, Hernandez D, Hillege H, Ittermann T, Kent JW, Kolcic I, Laatikainen T, Lahti J, Mateo Leach I, Lee CG, Lee JY, Liu T, Liu Y, Lobbens S, Loh M, Lyytikäinen LP, Medina-Gomez C, Michaëlsson K, Nalls MA, Nielson CM, Oozageer L, Pascoe L, Paternoster L, Polašek O, Ripatti S, Sarzynski MA, Shin CS, Narančić NS, Spira D, Srikanth P, Steinhagen-Thiessen E, Sung YJ, Swart KM, Taittonen L, Tanaka T, Tikkanen E, van der Velde N, van Schoor NM, Verweij N, Wright AF, Yu L, Zmuda JM, Eklund N, Forrester T, Grarup N, Jackson AU, Kristiansson K, Kuulasmaa T, Kuusisto J, Lichtner P, Luan J, Mahajan A, Männistö S, Palmer CD, Ried JS, Scott RA, Stancáková A, Wagner PJ, Demirkan A, Döring A, Gudnason V, Kiel DP, Kühnel B, Mangino M, Mcknight B, Menni C, O'Connell JR, Oostra BA, Shuldiner AR, Song K, Vandenput L, van

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964. Minikel EV, Vallabh SM, Lek M, Estrada K, Samocha KE, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LP, Gambetti P, Blevins J, Zhang S, Cohen Y, Chen W, Yamada M, Hamaguchi T, Sanjo N, Mizusawa H, Nakamura Y, Kitamoto T, Collins SJ, Boyd A, Will RG, Knight R, Ponto C, Zerr I, Kraus TF, Eigenbrod S, Giese A, Calero M, de Pedro-Cuesta J, Haïk S, Laplanche JL, Bouaziz-Amar E, Brandel JP, Capellari S, Parchi P, Poleggi A, Ladogana A, O'Donnell-Luria AH, Karczewski KJ, Marshall JL, Boehnke M, Laakso M, Mohlke KL, Kähler A, Chambert K, McCarroll S, Sullivan PF, Hultman CM, Purcell SM, Sklar P, van der Lee SJ, Rozemuller A, Jansen C, Hofman A, Kraaij R, van Rooij JG, Ikram MA, Uitterlinden AG, van Duijn CM; Exome Aggregation Consortium (ExAC), Daly MJ, MacArthur DG. Quantifying prion disease penetrance using large population control cohorts. Sci Transl Med. 2016; 20;8(322):322ra9.

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966. Ricaño-Ponce I, Zhernakova DV, Deelen P, Luo O, Li X, Isaacs A, Karjalainen J, Di Tommaso J, Borek ZA, Zorro MM, Gutierrez-Achury J, Uitterlinden AG, Hofman A, van Meurs J; BIOS consortium; Lifelines Cohort Study, Netea MG, Jonkers IH, Withoff S, van Duijn CM, Li Y, Ruan Y, Franke L, Wijmenga C, Kumar V. Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs. J Autoimmun. 2016;68:62-74.

967. Spjuth O, Krestyaninova M, Hastings J, Shen HY, Heikkinen J, Waldenberger M, Langhammer A, Ladenvall C, Esko T, Persson MÅ, Heggland J, Dietrich J, Ose S, Gieger C, Ried JS, Peters A, Fortier I, de Geus EJ, Klovins J, Zaharenko L, Willemsen G, Hottenga JJ, Litton JE, Karvanen J, Boomsma DI, Groop L, Rung J, Palmgren J, Pedersen NL, McCarthy MI, van Duijn CM, Hveem K, Metspalu A, Ripatti S, Prokopenko I, Harris JR. Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research.Eur J Hum Genet. 2016;24(4):521-8.

968. van den Berg SM, de Moor MH, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Esko T, Amin N, Gordon SD, Hansell NK, Hart AB, Seppälä I, Huffman JE, Konte B, Lahti J, Lee M, Miller M, Nutile T, Tanaka T, Teumer A, Viktorin A, Wedenoja J, Abdellaoui A, Abecasis GR, Adkins DE, Agrawal A, Allik J, Appel K, Bigdeli TB, Busonero F, Campbell H, Costa PT, Smith GD, Davies G, de Wit H, Ding J, Engelhardt BE, Eriksson JG, Fedko IO, Ferrucci L, Franke B, Giegling I, Grucza R, Hartmann AM, Heath AC, Heinonen K, Henders AK, Homuth G, Hottenga JJ, Iacono WG, Janzing J, Jokela M, Karlsson R, Kemp JP, Kirkpatrick MG, Latvala A, Lehtimäki T, Liewald DC, Madden PA, Magri C, Magnusson PK, Marten J, Maschio A, Mbarek H, Medland SE, Mihailov E, Milaneschi Y, Montgomery GW, Nauck M, Nivard MG, Ouwens KG, Palotie A, Pettersson E, Polasek O, Qian Y, Pulkki-Råback L, Raitakari OT, Realo A, Rose RJ, Ruggiero D, Schmidt CO, Slutske WS, Sorice R, Starr JM, St Pourcain B, Sutin AR, Timpson NJ, Trochet H, Vermeulen S, Vuoksimaa E, Widen E, Wouda J, Wright MJ, Zgaga L; Generation Scotland, Porteous D, Minelli A, Palmer AA, Rujescu D, Ciullo M, Hayward C, Rudan I, Metspalu A, Kaprio J, Deary IJ, Räikkönen K, Wilson JF, Keltikangas-Järvinen L, Bierut LJ, Hettema JM, Grabe HJ, Penninx BW, van Duijn CM, Evans DM, Schlessinger D, Pedersen NL, Terracciano A, McGue M, Martin NG, Boomsma DI. Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium. Behav Genet. 2016;46(2):170-82.

969. van Dongen J, Nivard MG, Willemsen G, Hottenga JJ, Helmer Q, Dolan CV, Ehli EA, Davies GE, van Iterson M, Breeze CE, Beck S; BIOS Consortium, Suchiman HE, Jansen R, van Meurs JB, Heijmans BT, Slagboom PE, Boomsma DI. Genetic and environmental influences interact with age and sex in shaping the human methylome. Nat Commun. 2016; 7;7:11115.

970. Wolters FJ, Koudstaal PJ, Hofman A, Duijn CM, Ikram MA. Serum apolipoprotein E is associated with long-term risk of Alzheimer's disease: The Rotterdam Study.Neurosci Lett. 2016; 23;617:139-42.

971. Yu B, Pulit SL, Hwang SJ, Brody JA, Amin N, Auer PL, Bis JC, Boerwinkle E, Burke GL, Chakravarti A, Correa A, Dreisbach AW, Franco OH, Ehret GB, Franceschini N, Hofman A, Lin DY, Metcalf GA, Musani SK, Muzny D, Palmas W, Raffel L, Reiner A, Rice K, Rotter JI, Veeraraghavan N, Fox E, Guo X, North KE, Gibbs RA, van Duijn CM, Psaty BM, Levy D, Newton-Cheh C, Morrison AC; CHARGE Consortium and the National Heart, Lung, and Blood Institute GO ESP*.Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk. Circ Cardiovasc Genet. 2016;9(1):64-70.

972. Zanoni P, Khetarpal SA, Larach DB, Hancock-Cerutti WF, Millar JS, Cuchel M, DerOhannessian S, Kontush A, Surendran P, Saleheen D, Trompet S, Jukema JW, De Craen A, Deloukas P, Sattar N, Ford I, Packard C, Majumder Aa, Alam DS, Di Angelantonio E, Abecasis G, Chowdhury R, Erdmann J, Nordestgaard BG, Nielsen SF, Tybjærg-Hansen A, Schmidt RF, Kuulasmaa K, Liu DJ, Perola M, Blankenberg S, Salomaa V, Männistö S, Amouyel P, Arveiler D, Ferrieres J, Müller-Nurasyid M, Ferrario M, Kee F, Willer CJ, Samani N, Schunkert H, Butterworth AS, Howson JM, Peloso GM, Stitziel NO, Danesh J, Kathiresan S, Rader DJ; CHD Exome+ Consortium; CARDIoGRAM Exome Consortium; Global Lipids Genetics Consortium. Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease. Science. 2016;11;351(6278):1166-71.