Cluster Biomedizintechnik Kooperationsmodell und ......MedTech Training Center: part of the...
Transcript of Cluster Biomedizintechnik Kooperationsmodell und ......MedTech Training Center: part of the...
Vision. Konzept. Realisierung Februar 2015
Cluster Biomedizintechnik
Kooperationsmodell und Forschungstrends
RWTH Aachen Campus Seite 2
Die RWTH Aachen University:
Eine der stärksten MINT-Universitäten Deutschlands
Quellen: RWTH Aachen Dezernat 6.0 Abteilung 6.3 (2014), Rankingreport der RWTH 2014
Studierende nach Wissenschaftsbereichen
7%
57%
23%
Natur-
wissenschaften
Ingenieur-
wissenschaften Medizin
Geistes-,
Gesellschafts-
und Wirtschafts-
wissenschaften
Finanzvolumen 2013: 894 Mio. €
davon Drittmittel: 354 Mio. €
An-Institute: 66 Mio. €
Studierende: >42 Tsd.
Professuren: 512
Institute, davon 260
Großinstitute 22
Fraunhofer 4
Graduiertenprogramme 25
Wirtschaftswoche 2014
2. Platz Maschinenbau
1. Platz Elektrotechnik
2. Platz Wirtschaftsingenieure
1. Platz Naturwissenschaften
2. Platz Informatik
Wettbewerber:
Karlsruhe, Darmstadt, München
DFG-Förderranking
2012 (€ Mio.)
Hochschulrankings Statistik
278 264 251
RWTHAachen
LMUMünchen
FU Berlin
13%
RWTH Aachen Campus Seite 3
Die Maßnahme: Ein zusammenhängender Campus für
Forschen. Lernen. Entwickeln. Leben.
Campus West
Campus Mitte
Campus Melaten
Existierender Campus Campus-Erweiterung
AC Zentrum
Uniklinik
Das Campus-Projekt sichert das
weitere Wachstum der RWTH
Aachen University
Es folgt dem Leitsatz
„Forschung braucht Fläche“
Ein zusammenhängender
Campus entsteht, der in das
öffentliche Leben integriert ist
Die Fläche wächst um
800.000 m² auf 2,5 km²
Das Investitionsvolumen
beträgt ca. 2 Mrd. €
10.000 Arbeitsplätze werden
direkt und indirekt geschaffen © StädteRegion Aachen/RWTH Aachen Campus GmbH
RWTH Aachen Campus Seite 4
Der Fokus: Relevante Fragen in 19 Forschungsclustern
Nachhaltige
Entergie
n.n.
Biomedizin-
technik
Logistik
Verfahrens-
technik
Photonik
Produktions-
technik
Molekulare
Technologie
& Katalyse
Kfz-Antriebs-
stränge
Schwerlast-
antriebe
Kunststoff-
technik
Alternative
Kraftstoffe
Faser-
verbundwerk-
stoffe
n.n.
Georessour-
cen/
Advanced
Metals and
Processes
Informations-
&
Kommunika-
tionstechno-
logie
n.n.
Weiße &
Grüne Bio-
technologie
Ultra High
Speed Mobile
Information &
Communi-
cation Geplantes Cluster
Startcluster
RWTH Aachen Campus Seite 5
Der Anspruch:
Relevante Themen schnell mit visionären Ideen angehen
© Shutterstock
RWTH Aachen Campus Seite 6
RWTH Aachen Campus:
catalyst for research and trigger for innovation
Research today • Long development times
• Narrow scope for solution
Solution Space
time
Knowing,
who knows
what.
Research yesterday • Long development times
• Narrow scope for solutions
Solution Space
time
Knowing,
where it
is written.
Research tomorrow • Shortened development times
• Ample room for solutions
Solution Space
time
Knowing,
where
knowledge
is created.
RWTH Aachen Campus Seite 7
“Enrollment of companies“: Cooperation model
to strengthen cooperation between industry and university
Research & Development
Advanced (vocational)
training
Industry
Research questions, resources, qualified staff
Research results,
resources, qualified staff
Development
RWTH
Lecturers, visiting professors, cases, resources
Qualified staff, certificates,
masters, doctorates
Enrollment
As a precondition for the constant and sustainable generation of third-party funds, there need to be
enough space for research and development.
Integrated and systemic research
Integration of competences and
disciplines in line with demand
Attractive range of services on
offer
Stabilize cooperation
Clear assignment of roles and
responsibilities
Access to resources and
technologies
Exploitation of synergistic effects
and economies of scale
RWTH Aachen Campus Symbiosis of science and
industry
RWTH Aachen Campus Seite 8
RWTH Aachen Campus: Aktuelle Entwicklungen
Cluster
Logistik
eLab – Fertigstellung
Sommer 2015
© LP12
Cluster
Nachhaltige Energie
E.ON Energy
Research Center
Cluster
Photonik
Fertigstellung
Herbst 2015
© KPF
Bilinguale
Kindertagesstätte
Bezug
Dezember 2014
© Campus GmbH
Cluster
Schwerlastantriebe
CWD – Bezug
Frühjahr 2015
© BLB NRW
Cluster
Produktionstechnik
Fertigstellung
Herbst 2016
© Henn
1 2
3
4
5
6
© RWTH Campus/Peter Winandy
Cluster
Biomedizintechnik
CBMS – Baubeginn
Frühjahr 2015
© C&P © RKW
7
1 2 3 4 5 6 7
RWTH Aachen Campus Seite 9
Cluster Biomedizintechnik: Erweiterung 2015 bis 2017
CBMS
ZBMT
C+P
Helmholtz Institute Biomedical Engineering
NGP2
University Hospital
ZBMT II
Leibniz
Institute Interactive
Materials
MTZ MedTech
Training
Center
© AME/RWTH
RWTH Aachen Campus Seite 10
ZMBT is a cornerstone of the
Campus activities.
The ZMBT is a joint project of
the City of Aachen, AGIT and
Campus GmbH.
GFA : 4.100 m²
- 25% of the space for newly
founded companies
- 75% of the space for
Campus companies
Tenants: 10 companies with a
total of 120 employees
The Center for Bio-Medical Engineering (ZBMT)
was the first new Campus building to be completed in July 2011
Source: Carpus + Partner AG, Aachen
RWTH Aachen Campus Seite 11
The first company moved into a second building on Biomedical
Engineering Cluster in 2011
This building for a planning and consultancy company specializing in life sciences is embedded in the
Bio-Medical Engineering Cluster
Headquarters of the firm of
Carpus + Partner AG with
around 200 employees
Specialization in Life
Sciences and High-Tech
Industries
Internationally operative
planning and consultancy
company
Open space office with more
than 3.700 square meters of
gross floor area for around
140 employees
Source: Carpus + Partner AG, Aachen
Source: Carpus + Partner AG, Aachen
RWTH Aachen Campus Seite 12
Biohybrid Implants (Cardiovascular and Lung)
Biohybrid Nanocarriers (Tumor Therapy)
System Labs: Prototype Production Lines
Experimental Imaging Facility
Completed by Feb. 2017
Center for Biohybrid Medical Systems - CBMS
RWTH Aachen Campus Seite 14
sketch: rha reicher haase + associierte, Aachen
MedTech Training Center: part of the Biomedical Engineering Cluster
University Hospital
BME Cluster
MedTech
Training Center
Lehrgebäude
2.500 m² (brutto)
Dienstleister
500 m² (brutto)
Fort- und Weiterbildung
500 m² (brutto)
Multifunktionssaal
500 m² (brutto)
RWTH Aachen Campus Seite 15
Cluster Biomedizintechnik: Forschungsthemen
• Medizinische Bildgebung & Bildgeführte Therapie
• Organunterstützung & Intelligente Implantate
• Biohybride Systeme & Tissue Engineering
• Personal Health Care & Telemonitoring
26.02.2
015
Folie Nr.
16
I3-Assist
Individual, Interactive & Integrated
Cardiopulmonary Assist
• Tailored gas exchanger by
modularity of components
• Adaption to individual disease-
specific course
MRI-safe guide wire
Marker Technology
Coating Technology
Micro-Pullwinding Technology
MiGi – Multifunctional Image Guided Interventions
0
10
20
30
40
0 10 20 30 40 50
Young's
modulu
s [G
Pa
]
Winding angle [°]
Adaptation of mechanical properties
in continuous process
Optimization
of marker setup
(different marker
materials,
concentrations
and distances)
Coeff
icie
nt of
slid
e f
rictio
n
Cycle no.
Evaluation of optimum
coating process
(pretreatment, friction
coefficient, wear
resistance)
Successful
in-vivo
testing with
real-time MRI
sequence
Soft tip Rigid shaft
Hydrophilic
coating MRI markers
3-layered
body
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HyTher
Interventionelle Hybridtherapie
HyTher
Image-guided interventional
hybrid therapy
Planning / Navigation Software, 3D-Visualization
3D Beschleunigungssensor
Auflagefläche
3D Beschleunigungssensor
3D Beschleunigungssensor
aufgespannte Ebene
w/o breathing detection with breathing detection
Movement / Breathing Compensation
Navigated placement of ballon-mounted stent
into right renal artery
Electromagnetically navigated in-situ fenestration
BioMon - HF
Biomonitoring in heart failure
• Detection of heart insufficiency and
concomittant diseases (hypertension,
atrial fibrillation, sleep apnea)
• Solution: Multisensor approach
Telemedizinisches Rettungsassistenzsystem
Realisierung einer umfassenden, nahtlosen und situationsgerechten
Versorgungskette kardiovaskulärer Notfälle durch Telemedizin
Tissue Eng Part A 2009, Biomaterials 2010
GoreTex Graft Biohybrid Implant
subtotal stenosis
Ovine Model, Carotid Artery, Explantation after 6 Month
technical:
textile scaffold
biological:
fibrin gel + cells
Biohybrid Vascular Graft - In Vivo Study
Imaging of Patient Customized Biohybrid Implants
Integration of biomarkers
In vivo monitoring of implants
Hemocompatibility
Inflammation
„Fate“ of implanted cells:
Integration
Remodelling
Degradation
PET-MRI
RWTH Aachen Campus Seite 28
Products & Spin-off Companies
Medos HIA VAD
Medos DeltaStream Impella® Recover® Circulite Synergy
28
RWTH Aachen Campus Seite 29
Vielen Dank für Ihre Aufmerksamkeit
© rha
Prof. Dr. Thomas Schmitz-Rode
Clusterleiter Biomedizintechnik
Institut für Angewandte Medizintechnik
RWTH Aachen University
Pauwelsstraße 20
52074 Aachen
Tel. 0241 – 80 87111
E-Mail [email protected]
URL www.rwth-campus.com
www.ame-hia.de