Clopidogrel Drug Study
2
Name of Drug General Action Specific Action Indications Contraindication s Adverse Reaction Nursing Responsibilities Clopidogrel 75 mg 1 tab PO OD Antiplatelet agents; Platelet aggregation inhibitors Inhibits platelet aggregation by irreversibly inhibiting the binding of ATP to platelet receptors. Therapeutic Effects: Decreased occurrence of atherosclerotic events in patients at risk. Reduction of atherosclerotic events (MI, stroke, vascular death) in patients at risk for such events including recent MI, acute coronary syndrome (unstable angina/non-Q-wave MI), stroke, or peripheral vascular disease. Contraindicated in: Hypersensitivity Pathologic bleeding (peptic ulcer, intracranial hemorrhage) Lactation. Use Cautiously in: Patients at risk for bleeding (trauma, surgery, or other pathologic conditions) History of GI bleeding/ulcer disease Severe hepatic impairment CNS: Depression, Dizziness, Fatigue, Headache. EENT: Epistaxis. Resp: Cough, Dyspnea. CV: Chest Pain, Edema, Hypertension. GI: GI Bleeding, Abdominal Pain, Diarrhea, Dyspepsia, Gastritis. Derm: Pruritus, Purpura, Rash. Hemat: Bleeding, Neutropenia, Thrombotic Thrombocytopenic Purpura. Metab: Hypercholesterolemi a. MS: Arthralgia, Back Pain. Misc: Fever, Hypersensitivity Reactions. Assessment Assess patient for symptoms of stroke, peripheral vascular disease, or MI periodically during therapy. Monitor patient for signs of thrombotic thrombocytic purpura (thrombocytopenia, microangiopathic hemolytic anemia, neurologic findings, renal dysfunction, fever). May rarely occur, even after short exposure (<2 wk). Requires prompt treatment. Implementation Discontinue clopidogrel 5-7 days before planned surgical procedures. PO: Administer once daily without regard to food. Patient/Family Teaching Instruct patient to take medication exactly as directed. Take missed doses as soon as possible unless almost time for next dose; do not double doses. Advise patient to notify health care professional promptly if fever, chills, sore throat, or unusual bleeding or bruising occurs. Advise patient to notify health care professional of medication regimen prior to treatment or surgery.
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A drug study on the drug Clopidogrel.
Transcript of Clopidogrel Drug Study
Name of Drug General Action Specific Action Indications Contraindications Adverse Reaction Nursing Responsibilities
Clopidogrel75 mg 1 tab PO OD
Antiplatelet agents;Platelet aggregation inhibitors
Inhibits platelet aggregation by irreversibly inhibiting the binding of ATP to platelet receptors.
Therapeutic Effects: Decreased occurrence of atherosclerotic events in patients at risk.
Reduction of atherosclerotic events (MI, stroke, vascular death) in patients at risk for such events including recent MI, acute coronary syndrome (unstable angina/non-Q-wave MI), stroke, or peripheral vascular disease.
Contraindicated in: Hypersensitivity Pathologic bleeding
(peptic ulcer, intracranial hemorrhage)
Lactation.Use Cautiously in:
Patients at risk for bleeding (trauma, surgery, or other pathologic conditions)
History of GI bleeding/ulcer disease
Severe hepatic impairment
CNS: Depression, Dizziness, Fatigue, Headache. EENT: Epistaxis. Resp: Cough, Dyspnea. CV: Chest Pain, Edema, Hypertension. GI: GI Bleeding, Abdominal Pain, Diarrhea, Dyspepsia, Gastritis. Derm: Pruritus, Purpura, Rash. Hemat: Bleeding, Neutropenia, Thrombotic Thrombocytopenic Purpura.Metab: Hypercholesterolemia. MS: Arthralgia, Back Pain.
Misc: Fever, Hypersensitivity Reactions.
AssessmentAssess patient for symptoms of stroke,
peripheral vascular disease, or MI periodically during therapy.
Monitor patient for signs of thrombotic
thrombocytic purpura (thrombocytopenia, microangiopathic hemolytic anemia, neurologic findings, renal dysfunction, fever). May rarely occur, even after short exposure (<2 wk). Requires prompt treatment.
ImplementationDiscontinue clopidogrel 5-7 days before
planned surgical procedures. PO: Administer once daily without regard to
food.
Patient/Family TeachingInstruct patient to take medication exactly
as directed. Take missed doses as soon as possible unless almost time for next dose; do not double doses.
Advise patient to notify health care
professional promptly if fever, chills, sore throat, or unusual bleeding or bruising occurs.
Advise patient to notify health care
professional of medication regimen prior to treatment or surgery.
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