Clinical Research Management 512 Leslie McIntosh [email protected] ) 314.747.7959 (office)
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Transcript of Clinical Research Management 512 Leslie McIntosh [email protected] ) 314.747.7959 (office)
![Page 2: Clinical Research Management 512 Leslie McIntosh lmcintosh@path.wustl.edu ) 314.747.7959 (office)](https://reader036.fdocuments.net/reader036/viewer/2022082422/56649e595503460f94b53b48/html5/thumbnails/2.jpg)
Agenda
Vocabulary
Levels of Measurement
Measures of Central Tendencies
Study design types (overview)
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Vocabulary Statistics
Levels of Measurement Continuous Discrete
(aka: Categorical) Dichotomous Nominal Ordinal
Measures of Central Tendencies Mean Median Mode Range
Confidence Interval
p-Value
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Statistics The study of inference – taking
information from a small amount of data (sample) and making generalizations to a larger setting (population)
Extrapolating from a sample to a population
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Levels of Measurement (Variable Types)
Continuous – variables that can take on any value in a given range
Discrete (aka: Categorical) – variables that have a limited number of values Dichotomous – two values Nominal – multiple values where order does
not matter Ordinal – multiple values where order does
matter
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Activity: Variable Types1. What is your gender?
2. What is your age?
3. What is the highest level of education you have completed?
4. What is your own yearly income?
5. What is your total household income, including all earners in your household?
6. What is your current marital status?
7. What is your religious affiliation?
8. What is your race?
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Measures of Central Tendencies
Mean Sum of all numbers divided by the total numbers within the
distribution
Median Midpoint of a distribution
Mode Most frequent number in the distribution
Range The spread of the distribution The smallest number to the largest number
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Activity: Central Tendencies
How much soda did you consume over the weekend?
Participant Amount Participant Amount
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Study Designs Descriptive
Analytic – hypothesis testing
1. Case reports
2. Case series
3. Ecologic (aka: correlational)
4. Cross-sectional
5. Case-control
6. Follow-up/cohort
7. Clinical trials