Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... ·...

14
L L “The Digestive System” an excerpt from Cliffs AP Biology, 2nd Ed. vs. “Goodwork” by Julia Tsao julia_comm2_03.indd 1-2 julia_comm2_03.indd 1-2 4/16/08 2:34:38 AM 4/16/08 2:34:38 AM

Transcript of Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... ·...

Page 1: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

LL

“Th

e D

iges

tive

Sys

tem

” an

exc

erpt

fro

m

Clif

fs A

P B

iolo

gy,

2nd

Ed.

vs. “G

oodw

ork

” by

Ju

lia

Tsa

o

julia

_com

m2_

03.in

dd

1-2

julia

_com

m2_

03.in

dd

1-2

4/16

/08

2:3

4:38

AM

4/16

/08

2:3

4:38

AM

Page 2: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

Ms.

T w

aass m

y el

evenen

th g

rade

BBio

logy

teeac

ha

er.

She

S re

mai

nsns to

this

dayay o

ne o

f thhee

gre

ates

t dt es

igne

rs I’

vIe

ever

me

met

.

Whe

n I w

aw

as in

my

junni

or y

ear o

f hf hig

h sc

hoooo

l, M

s. T

hahad

grac

iousus

ly a

ccep

teded

the

ardu

ouous

task

of tf

each

ing

AAd-

vvanc

ed P

lacce

men

t Bioio

logy

to m

ym

y ov

erly

aanx

ious

and

sdlig

htly

nneu

re

otic

cla

sass

of o

verr-a-a

chie

vers

. I w

as d

ecid

eid

dly

outut o

f pla

ce. H. H

ard

ly a

n nov

erac

hieev

erv in

any

y se

nse

of tf t

he w

ord

, I wI

as a

lonne

lye d

rifttee

r in

the

mmid

st o

f a a se

a of

wwou

ld-b

e d

ocd

tors

aand

sur

geoeo

ns. T

o m

a

ke m

am

atte

rs w

ororse

,

I hhate

dd scc

iienc

ee.

12

julia

_com

m2_

03.in

dd

3-4

julia

_com

m2_

03.in

dd

3-4

4/16

/08

2:3

4:39

AM

4/16

/08

2:3

4:39

AM

Page 3: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

The

Dig

esti

ve S

yste

m

Dig

estio

n is

the

chem

ical

bre

akdo

wn

of f

ood

into

sm

alle

r m

olec

ules

. In

an in

divi

dual

cel

l, di

gest

ion

is a

ccom

plis

hed

by in

trac

ellu

lar

dige

stio

n w

hen

a ly

osom

e co

ntai

ning

dig

estiv

e en

zym

es m

erge

s w

ith a

foo

d va

cuol

e. I

n m

ost a

nim

als,

how

ever

, the

foo

d in

gest

ed is

too

larg

e to

be

engu

lfed

by

indi

vidu

al c

ells

. Thu

s, f

ood

is fi

rst d

iges

ted

in a

gas

trov

ascu

lar

cavi

ty b

y ex

trac

ellu

lar

dige

stio

n an

d th

en a

bsor

bed

by in

divi

dual

cel

ls.

Dur

ing

dige

stio

n, f

our

diff

eren

t gro

ups

of m

olec

ules

are

com

mon

ly e

ncou

nter

ed. E

ach

is b

ro-

ken

dow

n in

to it

mol

ecul

ar c

ompo

nent

s by

spe

cifi c

enz

ymes

, and

fol

low

s:

1. S

tarc

hes

are

brok

en d

own

into

glu

cose

mol

ecul

es.

2. P

rote

ins

are

brok

en d

own

into

am

ino

acid

s.

3. F

ats

(or

lipid

s) a

re b

roke

n do

wn

into

gly

cero

l and

fat

ty a

cids

.

4. N

ucle

ic a

cids

are

bro

ken

dow

n in

to n

ucle

otid

es.

In h

uman

s an

d ot

her

mam

mal

s, d

iges

tion

follo

ws

the

follo

win

g se

quen

ce o

f ev

ents

. In

part

icu-

lar,

note

whi

ch k

inds

of

mol

ecul

es a

re d

iges

ted

(bro

ken

dow

n) a

nd b

y w

hich

enz

ymes

. Sin

ce

enzy

mes

are

spe

cifi c

for

dif

fere

nt b

onds

, onl

y a

repr

esen

tativ

e fe

w o

f th

e nu

mer

ous

enzy

mes

ar

e gi

ven.

1.

Mou

th.

Saliv

ary

amyl

ase,

sec

rete

d in

to th

e m

outh

by

the

saliv

ary

glan

ds, b

egin

s

the

bre

akdo

wn

of s

tarc

h in

to m

alto

se (

a di

sacc

hari

de).

Che

win

g re

duce

s th

e si

ze

of

food

par

ticle

s, th

ereb

y in

crea

sing

the

surf

ace

area

upo

n w

hich

am

ylas

e an

d su

b

s

eque

nt e

nzym

es c

an o

pera

te. F

ood

is s

hape

d in

to a

bal

l, or

bol

us, a

nd th

en s

wal

-

l

owed

.

2.

Pha

rynx

. Whe

n fo

od is

sw

allo

wed

and

pas

sed

into

the

thro

at, o

r ph

aryn

x, a

fl ap

of

t

issu

e, th

e ep

iglo

ttis

, blo

cks

the

trac

hea

so th

at s

olid

and

liqu

id m

ater

ial e

nter

onl

y

the

eso

phag

us.

3.

Eso

phag

us. F

ood

mov

es th

roug

h th

e es

opha

gus,

a tu

be le

adin

g to

the

stom

ach,

by

m

uscu

lar

cont

ract

ions

cal

led

peri

stal

sis.

4.

Sto

mac

h. T

he s

tom

ach

secr

etes

gas

tric

jui

ce, a

mix

ture

of

dige

stiv

e en

zym

e an

d

hyd

roch

lori

c ac

id, (

HC

l), a

nd s

erve

s a

vari

ety

of f

unct

ions

, as

follo

ws:

• S

tora

ge. B

ecau

se o

f its

acc

ordi

onlik

e fo

lds,

the

wal

l of

the

stom

ach

can

e

xpan

d to

sto

re tw

o to

fou

r lit

ers

of m

ater

ial.

• M

ixin

g. T

he s

tom

ach

mix

es th

e fo

od w

ith w

ater

and

gas

tric

juic

e to

pro

duce

a c

ream

y m

ediu

m c

alle

d ch

yme.

• P

hysi

cal b

reak

dow

n. M

uscl

es c

hurn

the

cont

ents

of

the

stom

ach,

phy

sica

lly

b

reak

ing

food

dow

n in

to s

mal

ler

part

icle

s. I

n ad

ditio

n, H

Cl f

rom

the

gast

ric

jui

ce d

enat

ures

(or

unf

olds

) pr

otei

ns a

nd lo

osen

s th

e ce

men

ting

subs

tanc

es

b

etw

een

cells

of

the

food

. Als

o, th

e H

Cl k

ills

mos

t bac

teri

a th

at m

ay

a

ccom

pany

the

food

.

• C

hem

ical

bre

akdo

wn.

Pro

tein

s ar

e ch

emic

ally

bro

ken

dow

n (d

iges

ted)

by

the

enzy

me

peps

in. S

tom

ach

cells

pro

duci

ng p

epsi

n ar

e pr

otec

ted

from

sel

f -d

iges

tion

beca

use

they

pro

duce

and

sec

rete

an

inac

tive

form

, pep

sino

gen.

Pep

sion

ogen

is a

ctiv

ated

into

pep

sin

by H

Cl,

whi

ch is

pro

duce

d by

othe

r st

omac

h ce

lls. T

hus,

onl

y af

ter

peps

inog

en is

sec

rete

d in

to th

e st

omac

h

ca

vity

can

pro

tein

dig

estio

n be

gin.

Onc

e pr

otei

n di

gest

ion

begi

ns, t

he s

tom

ach

is p

rote

cted

by

a la

yer

of m

ucus

sec

rete

d by

stil

l oth

er c

ells

in th

e hu

man

linin

g. F

ailu

re o

f th

e m

ucus

to p

rote

ct th

e st

omac

h ca

n le

ad to

lesi

ons,

or

pept

ic u

lcer

s. L

ong

belie

ved

to b

e ca

used

by

stre

ss, d

iet,

or o

ther

fac

tors

,

mos

t ulc

ers

are

now

kno

wn

to b

e ca

used

by

bact

eria

and

can

be

succ

essf

ully

trea

ted

with

ant

ibio

tics.

• C

ontr

olle

d re

leas

e. M

ovem

ent o

f ch

yme

into

the

smal

l int

estin

e is

reg

ulat

ed

by

a v

alve

at t

he e

nd o

f th

e st

omac

h, th

e py

lori

c sp

hinc

ter.

Gas

trin

is p

rod-

uced

by

cells

in th

e st

omac

h lin

ing

whe

n fo

od r

each

es th

e st

omac

h or

whe

n

the

nerv

ous

syst

em, t

hrou

gh s

mel

l or

sigh

t, se

nses

the

avai

labi

lity

of f

ood.

Gas

trin

ent

ers

the

bloo

d st

ream

and

stim

ulat

es o

ther

cel

ls o

f th

e st

omac

h to

prod

uce

gast

ric

juic

es.

5.

Sm

all i

ntes

tine

. The

fi rs

t tw

enty

-fi v

e m

eter

s of

the

smal

l int

estin

e, th

e du

oden

um,

con

tinue

s th

e di

gest

ion

of s

tarc

hes

and

prot

eins

(w

hich

beg

an in

the

mou

th a

nd

sto

mac

h, r

espe

ctiv

ely)

as

wel

l as

all r

emai

ning

foo

d ty

pes

(inc

ludi

ng fa

ts a

nd

nuc

leot

ides

). S

ecre

tin is

pro

duce

d by

the

cells

lini

ng th

e du

odeu

m w

hen

food

e

nter

s. S

ecre

tin s

timul

ates

the

panc

reas

e to

pro

duce

bic

arbo

nate

whi

ch, w

hen

de

p

osite

d in

to th

e sm

all i

ntes

tine,

neu

tral

ize

the

acid

ity o

f th

e ch

yme.

Foo

d le

aves

t

he d

uode

num

and

ent

ers

the

jeju

num

and

then

the

ileum

(th

e fi n

al p

art o

f th

e sm

all

int

estin

e). E

nzym

es f

or th

ese

vari

ous

proc

esse

s or

igin

ate

from

the

follo

win

g

s

ourc

es.

• S

mal

l int

esti

ne. T

he w

all o

f th

e sm

all i

ntes

tine

is th

e so

urce

of

vari

ous

enz

ymes

, inc

ludi

ng p

rote

olyt

ic e

nzym

es (

or p

rote

ases

, enz

ymes

that

dig

est

pr

otei

ns, s

uch

as a

min

opep

tida

se),

mal

tase

and

lact

ase

(for

the

dige

stio

n

o

f di

sacc

hari

des)

, and

pho

spha

tase

s (f

or th

e di

gest

ion

of n

ucle

otid

es).

Cho

lecy

stok

inin

is p

rodu

ced

by th

e sm

all i

ntes

tine

to s

timul

ate

the

gallb

lad

d

er to

rel

ease

bile

and

the

panc

reas

to r

elea

se it

s en

zym

es.

• P

ancr

eas.

The

pan

crea

se p

rodu

ces

vari

ous

enzy

mes

, inc

ludi

ng t

ryps

in

a

nd c

hym

otry

psin

(pr

otea

ses)

, lip

ase

(dig

estio

n of

fat

s), a

nd p

ancr

eati

c

am

ylas

e (d

iges

tion

of s

tarc

h). T

hese

and

oth

er e

nzym

es, p

acka

ged

in a

n

al

kalin

e so

lutio

n th

at s

erve

s to

neu

tral

ize

the

HC

l in

the

chym

e, e

nter

the

duo

denu

m th

roug

h th

e pa

ncre

atic

duc

t.

• L

iver

. The

live

r pr

oduc

es b

ile, w

hich

fun

ctio

ns to

em

ulsi

fy f

ats.

Em

ulsifi c

a-

tion

is th

e br

eaki

ng u

p of

fat

glo

bule

s in

to s

mal

ler

fat d

ropl

ets,

incr

easi

ng

th

e su

rfac

e ar

ea u

pon

whi

ch f

at-d

iges

ting

enzy

mes

(lip

ase,

or

exam

ple)

can

oper

ate.

Sin

ce b

ile d

own

not c

hem

ical

ly c

hang

e an

ythi

ng, i

t is

not a

n en

-

34

julia

_com

m2_

03.in

dd

5-6

julia

_com

m2_

03.in

dd

5-6

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AM

4/16

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Page 4: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

zy

me.

Bile

is a

lso

alka

line,

ser

ving

to h

elp

neut

raliz

e th

e H

Cl i

n th

e ch

yme.

The

bile

is s

tore

d ad

jace

nt to

the

liver

in th

e ga

llbla

dder

and

fl ow

s th

roug

h

th

e bi

le d

uct w

here

it m

erge

s w

ith th

e pa

ncre

atic

duc

t.

The

rem

aind

er o

f th

e sm

all i

ntes

tine

(nea

rly

six

met

ers)

abs

orbs

the

brea

k-

do

wn

prod

ucts

of

food

. It i

s ch

arac

teri

zed

by v

illi a

nd m

icro

villi

, fi n

gerl

ike

proj

ectio

ns o

f th

e in

test

inal

wal

l tha

t inc

reas

e its

tota

l abs

orpt

ive

surf

ace

area

. Am

ino

acid

s an

d su

gars

are

abs

orbe

d in

to b

lood

cap

illar

ies,

whi

le m

ost

of

the

fatty

aci

ds a

nd g

lyce

rol a

re a

bsor

bed

into

the

lym

phat

ic s

yste

m.

6.

Lar

ge in

test

ine.

The

mai

n fu

nctio

n of

the

larg

e in

test

ine,

or

colo

n, is

the

reab

sorp

-

t

ion

of w

ater

to f

orm

sol

id w

aste

r, or

fec

es. V

ario

us h

arm

less

bac

teri

a liv

e in

the

l

arge

inte

stin

e, in

clud

ing

som

e th

at p

rodu

ce v

itam

in K

, whi

ch is

abs

orbe

d th

roug

h

the

inte

stin

al w

all.

At t

he b

egin

ning

of

the

larg

e in

test

ine,

ther

e is

a s

hort

bra

nch

to

a d

ead-

end

pouc

h w

hich

bea

rs a

fi ng

erlik

e pr

ojec

tion

calle

d th

e ap

pend

ix. O

ther

tha

n a

poss

ible

rol

e in

the

imm

une

resp

onse

, the

app

endi

x is

sig

nifi c

ant o

nly

whe

n

it b

ecom

es infl a

med

, cau

sing

app

endi

citis

. Foo

d th

en tr

avel

s up

war

d in

the

asce

nd-

ing

col

on. T

he f

ood

trav

els

acro

ss th

e ab

dom

en in

the

tran

sver

se c

olon

, goe

s ba

ck

dow

n th

e ot

her

side

of

the

body

in th

e de

scen

ding

col

on, a

nd th

en th

roug

h th

e si

g-

m

oid

colo

n.

7.

Fec

es a

re s

tore

d at

the

end

of th

e la

rge

inte

stin

e, in

the

rect

um, a

nd e

xcre

ted

thr

ough

the

anus

.

Too

mee,

B

ioolo

ggy

wwas

mm

errel

yy thh

e lee

sser

of tt

woo

evils

; 5

6ju

lia_c

omm

2_03

.indd

7-

8ju

lia_c

omm

2_03

.indd

7-

84/

16/0

8 2

:34:

40 A

M4/

16/0

8 2

:34:

40 A

M

Page 5: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

a w

eelco

mme

altte

r-na

tivve

to t

he pp

er-

pet

uual

head

aache

I

kknew

aw

aaite

d

me

in P

hhysi

cs..

Do

-in

g w

ell

in B

ioolo

gy,

th

ooug

h dd

esiraa

ble

too

m

ee in

the

abb

stra

ctt,

wass

ha

rdly

aa

hig

hh p

riiorit

y o

n mm

y si

xx-te

een y

eear-

oldd

ag

en-

daa.

MM

y p

lan

wwas

too

bre

eeze

bby

in tt

he

clas

s, g

et mm

y unn

its,

annd

get

thee

hel

l out

.

OOn

thhe

fi rrst

d

aay

of

cclas

s,

eacch

st

uuden

t ww

as

giv

enn

an

eig

ht--

ppo

unnd

te

xxtb

ooo

k an

dd

assi

ggne

d

four

ch

app-

tters

of

reead

ing

, d

uue

the

next

d

ay..

I w

as

aghaa

st——

my

“eass

y”

sciee

nce

class

s ww

as

turnn

ing

oout

too

be

wway

m

orre

woo

rk t

hhan

I ha

d

imaag

ined

. So

I d

id ww

hat

anyy

diss

inte

reest

ed

and

le

thar

gic

kid

wo

uld

do

:: I

dday

drre

ameed

m

yy w

ayy

thrro

ughh

clas

ss, to

sssed

the

boo

ok

in

myy

lockk

er

annd

w

eent t

oo g

o ww

atch

aa m

ovvi

e w

ith mm

y eq

ually

dis

intte

r-ess

ted

aand

letth

arg

ic fr

iennd

s.

TThhe

neextt

mmonn

th a

t sc

hoool

wwas

hel

l.MM

s.

TT’s

bbiw

eekkl

y ex

ams

hhad

me

teet

erin

g oo

n th

e eed

gee

of

ddis

astee

r—d

isas

terr

bei

ngg C

-mmin

us,

a m

ere

2%%

awayy

fro

mm th

e d

reaad

ed DD

. A

n dd I

waas

n’t aa

lonee

. Mo

re

thann

haa

lf oo

f m

yy cl

ass-

matt

es

wer

ee stt

rug

gllin

g

righht

thee

re ww

ith mm

e, s

oom

e fa

rinng

evve

n ww

ors

ee th

ann m

y ssh

ammef

ul

C-m

inuus

. So

me-

thin

gg h

add to

bbe

doo

ne. I

sw

oree

too

myys

elf t

hat I

wo

uuld

brrin

g u

pp

my

grra

de

beff

ore

the

midd

-see

mees

ter

grra

dinn

g pp

erio

d.

AAnd

sso

I fi

nnal

lyy u

neear

thhed

tth

e nee

glee

cteed

eei

ghht

-po

und

t ee

xtb

ooo

k aan

d d

raag

geed

it b

ackk

hoomm

e ww

ith m

ee. I

flfl ip

pped

it o

peen

, o

pptimm

isttic

aand

read

y too

read

, beef

ore

78

julia

_com

m2_

03.in

dd

9-10

julia

_com

m2_

03.in

dd

9-10

4/16

/08

2:3

4:41

AM

4/16

/08

2:3

4:41

AM

Page 6: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

slam

mmin

g i

t shh

uut a

fter

aa m

ere

155 m

inut

ess o

f ef

-fo

rt.

Thee

text

bo

okk,,

an

agedd

,, d

ecre

ppiitt

thin

g,

wwas

a

nnig

htm

are;

aa g

litte

riinngg

sym

boo

ll o

f ev

erryyt

hing

II h

at-

e dd aa

bo

ut b

iolloo

ggy

and

ssci

ence

iinn

gen

eraal

. It

lacc

kked

an

y dd

iisstin

gui

shabb

llee c

larit

y, aa

nd w

as fifi

lled

wiitthh

pag

e aaf

-te

r p

agee

of

bo

ringg

sc

ienc

e-tte

xt

andd

co

mp

liccaat

ed

ddiiaa

-gg

ram

s. I

fel

tt ch

eate

d,

aannd

ro

yalllyy

scr

ewedd

.. H

ow

wwaas

I s

upp--

poo

ssed

to

dig

mmyys

elf

out

off

mmy

hole

wwith

suc

hh aa

shit

teexxt

bo

ok??

I wen

t too

ssch

oo

l the

neex

t day

, irr

ittaate

d a

ndd oo

n th

e o

ffffeens

ive.

I nne

ed-

ed to

kno

w ww

hat I

was

supp

ppo

sed

to dd

o; g

iven

mmy

sco

reess

in th

e ccll

ass

and

lack

ing

tthhe

res

our

cess

I ne

ededd

tto

stu

ddyy

on

my

oow

n. WW

hheen

Ms.

T w

alke

d in

ttoo o

ur s

ixth

ppeer

iod

Bio

lloogg

y cl

asss,

for

the

fifi rst

tim

ee,,

I sat

uupp

a li

ttle

str

aiigg

hter

. I h

add a

pur

po

ssee t

hat

ddaayy

. Ms.

T cc

olle

ctt-

ed h

er nn

otes

and

maadd

e he

r waayy

up

to thh

ee ov

erhhee

ad p

roojjee

ct

o

r,fl i

pp

ed thh

ee sw

itch,

andd

beg

an tthh

at d

ay’s

lleect

uree

oon th

e

dd

igess

tt-iv

e sy

stem

. SShe

beg

ann tt

he le

ssoo

n, a

nd II

wat

chheed

,

amm

azedd

, as

I wen

t ho

mme

that

nig

ht a

nd re

aad o

ver

my

lect

urree

not

e

ss se

vera

l tim

ees. I

had

a fe

w u

n-an

sswwer

ed q

uest

ions

I nee

eeded

ans

wer

ed, ss

o

I fl

ipppp

ed t

hro

ugghh

my

text

bo

ok

in a

hhaal

f-he

arte

d a

ttem

ptt

to fi

ll in

the

blaa

n

ks. T

o mm

y su

rpri

se, I

foun

d m

ysel

f geett

tting

lost

in t

he b

ooo

k. Im

ages

of

in

test

inee

ss an

d e

n-

zym

es d

ance

d t

hroo

uugh

my

head

, pai

nttiinn

g a

cle

ar

p

ictu

re o

f thhee

func

-tio

nalit

y, fl

uid

ity, a

n dd iill

lust

rious

ness

of t

hhee h

uman

bb

ood

y. I

was

amm

az-

ed a

t th

e p

ow

er o

f Ms.

T’s

lect

ure,

its

visu

aall c

lari

ty

, anndd

ho

w it

hadd

b

een

able

to

act

as

such

aa s

tro

ng c

om

ple

meenn

t

to

the

vver

bo

se

910

julia

_com

m2_

03.in

dd

11-1

2ju

lia_c

omm

2_03

.indd

11

-12

4/16

/08

2:3

4:43

AM

4/16

/08

2:3

4:43

AM

Page 7: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

annd

onn

e-d

iime

siio

nal

te

xtbb

oo

k. H

er

teac

hin

g

mmet

hod

waas

so

absu

rdly

si mm

ple

: sshe

took

thee

fact

s la

id o

uut in

the

i

mpo

ssib

lee te

xt-

boo

ok

aand

ppre

seen

tedd

th

eem

in a

str

aig

htf

orr

ww

ard

, vis

uually

-co

mmp

eellin

gg w

ay.. I

hadd

nevv

er s

eeen

sciee

nce

in

tthi

s ki

nd o

f lig

ht,

andd

I w

aas in

trig

ued

andd

exc

itted

. Ms.

T’s

mmet

hod

s

wwe

re,

I q

uic

kly

learr

ned

, inv

aalua

ble

to

mmy

suucc

ess

in t

he c

our

se,,

aan

d in

lifee

. I

was

ins pp

iredd

. I w

aante

dd t

o lee

arn

eever

ythhi

ng I

ccoul

d a

bb

oout

the

lifee

sci

ence

s.

Latee

r thh

at y

eear,

aafte

r M

s. T

’s c

lass

, I s

eent

outt

mm

y un

iverr

sity

ap

plic

aa-tio

nns w

ith a

maj

oor in

BBio

logg

y. M

s. T

’s tee

achi

ngg

hhad

stir

reed

in m

e a

sens

e o

f pp

assii

on

ffor

thhe

sciie

ncees

tha

t I h

add n

ever

bb

efo

re k

no

wn

exi

ste

d.

Bio

log

y A

P ww

ith

Ms.

T t

auug

ht mm

e to

lloo

k foo

r

dd

esig

n in

the

mo

st uu

nexp

ecte

d o

f

pla

cces,

tto ta

ke ri

ggid

and

sttr

uctu

rred

exxp

erie

nc

ee

s an

d id

eeas,

and

imbb

ue in

them

a s

ense

Ms.

T11

12ju

lia_c

omm

2_03

.indd

13

-14

julia

_com

m2_

03.in

dd

13-1

44/

16/0

8 2

:34:

48 A

M4/

16/0

8 2

:34:

48 A

M

Page 8: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

The

Dig

esti

ve S

yste

m

Dig

edi

geen

zyto

be

extr

Dur

ike

n

In h

ula

r, n

enzy

are

g

o

f fo

od p

artic

les,

ther

eby

incr

easi

ng

seq

uent

enz

ymes

can

ope

rate

. Foo

d is

sha

ped

into

a b

all,

or b

olus

, and

then

sw

al-

l

owed

.

2. P

hary

nx. W

hen

food

is s

wal

low

ed a

nd p

asse

d in

to th

e th

roat

, or

phar

ynx,

a fl

ap o

f

tis

sue,

the

epig

lott

is, b

lock

s th

e tr

ache

a so

that

sol

id a

nd li

quid

mat

eria

l ent

er o

nly

the

eso

phag

us.

3. E

soph

agus

. Foo

d m

oves

thro

ugh

the

esop

hagu

s, a

tube

lead

ing

to th

e st

omac

h, b

y

m

uscu

lar

cont

ract

ions

cal

led

peri

stal

sis.

4. S

tom

ach.

The

sto

mac

h se

cret

es g

astr

ic j

uice

, a m

ixtu

re o

f di

gest

ive

enzy

me

and

h

ydro

chlo

ric

acid

, (H

Cl)

, and

ser

ves

a va

riet

y of

fun

ctio

ns, a

s fo

llow

s:

Sto

rage

. Bec

ause

of

its a

ccor

dion

like

fold

s, th

e w

all o

f th

e st

omac

h ca

n ex

pand

to s

tore

two

to f

our

liter

s of

mat

eria

l.

Mix

ing.

The

sto

mac

h m

ixes

the

food

with

wat

er a

nd g

astr

ic ju

ice

to p

rodu

ce

a c

ream

y m

ediu

m c

alle

d ch

yme.

•P

hysi

cal b

reak

dow

n. M

uscl

es c

hurn

the

cont

ents

of

the

stom

ach,

phy

sica

lly

bre

akin

g fo

od d

own

into

sm

alle

r pa

rtic

les.

In

addi

tion,

HC

l fro

m th

e ga

stri

c

juic

e de

natu

res

(or

unfo

lds)

pro

tein

s an

d lo

osen

s th

e ce

men

ting

subs

tanc

es

betw

een

cells

of

the

food

. Als

o, th

e H

Cl k

ills

mos

t bac

teri

a th

at m

ay

Dig

estio

n is

the

chem

ical

bre

akdo

wn

of f

ood

into

sm

alle

r m

olec

ules

. In

an in

divi

dual

cel

l,di

gest

ion

is a

ccom

plis

hed

by in

trac

ellu

lar

dige

stio

n w

hen

a ly

osom

e co

ntai

ning

dig

estiv

ege

stiv

een

zym

es m

erge

s w

ith a

foo

d va

cuol

e. I

n m

ost a

nim

als,

how

ever

, the

foo

d in

gest

ed is

too

larg

el

to b

e en

gulf

ed b

y in

divi

dual

cel

ls. T

hus,

foo

d is

fi rs

t dig

este

d in

aga

stro

vasc

ular

cavi

tyca

vity

by

by

extr

acel

lula

rdi

gest

ion

and

then

abs

orbe

d by

indi

vidu

al c

ells

.

Dur

ing

dige

stio

n, f

our

diff

eren

t gro

ups

of m

olec

ules

are

com

mon

ly e

ncou

nter

ed. E

ach

is b

ro-

ach

is b

roac

his

bro

ken

dow

n in

to it

mol

ecul

ar c

ompo

nent

s by

spe

cifi c

enz

ymes

, and

fol

low

s:

1. S

tarc

hes

are

brok

en d

own

into

glu

cose

mol

ecul

es.

ecul

es

2P

rote

ins

are

brok

endo

wn

into

amin

oac

idss

hyd

roch

lori

c ac

id, (

HC

l), a

nd s

erve

s a

vari

ety

of f

unct

ions

, as

follo

ws:

gp

yp

yd

ih

di

tb

llt

bl

dth

ld

thon

s, a

s fo

llow

s:tio

ns, a

s fo

llow

s:

• S

tora

ge. B

ecau

se o

f its

acc

ordi

onlik

e fo

lds,

the

wal

l of

the

stom

ach

can

hew

all

expa

nd to

sto

re tw

o to

fou

r lit

ers

of m

ater

ial.al

•ch

easo

that

solid

ad

Mix

ing

ndliq

uind

liqui

. The

sto

mac

h m

ixes

the

food

with

wat

er a

nd g

astr

ic ju

ice

to p

rodu

ce

,p

y,

pp

y,

pid

mat

eria

lent

eron

lyid

mat

eria

lent

eron

lyd

gast

ric

juic

e to

pro

er a

nd g

astr

ic ju

ice

to p

rodu

ce

er a

nd g

astr

ic ju

ice

to p

rodu

c a

cre

am y

med

ium

cal

led

qqch

yme

yy.

• P

hysi

cal b

reak

dow

nl

dit

tht

. Mus

cles

chu

rn th

e co

nten

ts o

f th

e st

omac

h, p

hysi

cally

h

bof

the

stom

ach,

phy

sica

llynt

ents

of

the

stom

ach,

phy

sica

lly

brea

king

foo

d do

wn

into

sm

alle

r pa

rtic

les.

In

addi

tion,

HC

l fro

m th

e ga

stri

c

e le

adin

g to

the

stom

ach,

by

e

lead

ing

to th

e st

omac

h, b

y

addi

tion,

HC

l fro

m th

e ga

stri

addi

tion,

HC

l fro

m th

e ga

stri

c

juic

e de

natu

res

(or

unfo

lds)

pro

tein

s an

d lo

osen

s th

e ce

men

ting

subs

tanc

es

astr

icju

ice

am

ixt

betw

een

cells

of

the

food

. Als

o, th

e H

Cl k

ills

mos

t bac

teri

a th

at m

ay

ure

ofdi

gest

ive

enzy

me

and

ure

ofdi

gest

ive

enzy

me

and

llsm

ostb

acte

ria

that

may

llsm

ostb

acte

ria

that

may

1314

est

sti

ym e e ac ing

do

uma

note

yme

give

offo

odpa

rtic

les,

ther

eby

incr

easi

ngth

esu

rfac

ear

eaup

onw

hich

amyl

ase

and

sub

2.P

rote

ins

are

brok

endo

wn

into

amin

oac

ids.s

ubub al-

p of

fp

of ff

nly

nly

nly by

by

mix

ture

of

dige

stiv

e en

zym

e an

d

ure

of d

iges

tive

enzy

me

and

i

tf

fti

fll

gth

esu

rfac

ear

eaup

onw

hich

amyl

ase

and

sub

ear

eaup

onw

hich

amyl

ase

an

c g

GE

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGEEEEEEEE

GGGGGE

GGGGGGticu-

icu

ticu-

ticu-cuc

nce

mes

m

es

s GC

HA

Nl b

reak

dow

n of

foo

d in

to s

mal

ler

mol

ecul

es. I

n an

indi

vidu

al c

ell,

com

plis

hed

by in

trac

ellu

lar

dige

stio

n w

hen

a ly

osom

e co

rges

with

a f

ood

vacu

ole.

In

mos

t ani

mal

s, h

owev

er, t

he f

oofe

d by

indi

vidu

al c

ells

. Thu

s, f

ood

is fi

rst d

iges

ted

in a

gas

tla

rdi

gest

ion

and

then

abs

orbe

d by

indi

vidu

estio

n, f

our

diff

eren

t gro

nto

it m

olec

ular

com

pon

tarc

hes

are

brok

en d

ow

are

brok

endo

wNN

GGGGGGN

GN

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omm

onl

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ules

.

GGGGGGGGGA

NGGGG

Ah is

bro NNNN

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cells

.

NNNNNAr

cavi

ty b

y

Ag di

gest

ive

di

tl

2. P

rote

ins

are

brok

en d

own

into

am

ino

acid

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gest

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Fat

sn

al

na

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cero

l and

fat

ty

rol a

nd f

atty

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en d

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gest

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gdi

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lipid

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som

eco

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som

eco

anim

alN

uce

cow

ever

, ow

ever

, de

s.eddes

oo

ed is

too

larg

eed

is to

o la

rgth

e fo

oth

e fo

nce

of e

vent

s. I

nnc

e of

eve

nts.

In

owin

g se

qow

ing

seq

and

othe

r m

amm

als,

dig

estio

n fo

lloce

lls.

ells

Inhu

mnd

ivid

und

ivid

ula

r, no

te w

hich

kin

ds o

f m

olec

ules

are

dig

este

d (b

roke

n do

wn)

and

by

whi

ch e

nzym

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Page 9: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

The Digestive System

Digestion is the chemical breakdown of food into smaller molecules. In an individual cell, digestion is accomplished by intracellular digestion when a lyosome containing digestive enzymes merges with a food vacuole. In most animals, however, the food ingested is too large to be engulfed by individual cells. Thus, food is fi rst digested in a gastrovascular cavity by extracellular digestion and then absorbed by individual cells.

1516

high

light

, and

you

will

suc

ceed

.

co

rnel

l sty

le n

otes

: fol

d th

e pa

ge in

to tw

o co

lum

ns.

voca

bula

ry w

ords

go

on th

e le

ft, d

efi n

itio

ns g

o on

the

righ

t.

fl

ash

card

s ar

e th

e be

st w

ay to

mem

oriz

e an

ythi

ng.

clus

ters

! whe

n yo

u th

ink

of in

form

atio

n du

ring

the

exam

, you

’ll im

agin

e an

imag

e of

the

clus

ter

in y

our

min

d. it

’s vi

sual

lear

ning

. if y

ou w

rite

it e

noug

h ti

mes

, you

’ll re

mem

ber

it.

the

fi rst

lett

er w

ill c

ue y

ou in

. tak

e al

l the

fi rs

t let

ters

and

mak

e a

sent

ence

out

of t

hem

. you

’ll re

mem

ber

it fo

reve

r.

julia

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-18

4/16

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4/16

/08

2:3

5:11

AM

Page 10: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

Dig

esti

on

Ext

race

llu

lar

dige

stio

n

Per

ista

lsis

Ch

yme

Intr

acel

lula

rdi

gest

ion

Sal

ivar

y am

ylas

e

Hyd

roch

lori

c ac

id

Pep

sin

1718

Diges

tion

Intr

acellu

lar

Diges

tion

Extr

acellu

lar

Diges

tion

4 gr

oups

of m

olec

ules

in d

igest

ion

Star

ches

Prot

eins

Fats

Nucle

ic Ac

ids

chem

ical b

reak

down

of f

ood

into

sm

aller

mol

ecul

es

indiv

idual c

ell

lyso

som

e m

erge

s with

a f

ood

vacu

ole

mos

t an

imals

food

mus

t be

bro

ken

down

food

f ir

st t

aken

into

gas

trov

ascu

lar

cavit

yth

en d

igest

ed a

nd a

bsor

bed

Each

is b

roke

n do

wn

into

it m

olec

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com

pone

nts

by s

pecif

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nzym

es

Brok

en d

own

into

glu

cose

mol

ecul

es.

Brok

en d

own

into

am

ino

acids

.

(Lipi

ds) B

roke

n do

wn

into

gly

cero

l and

fat

ty a

cids.

Brok

en d

own

into

nuc

leot

ides.

julia

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4/16

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Page 11: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

In a

n i

ndi

vidu

al c

ell,

dig

esti

on

is a

ccom

plis

hed

by

intr

acel

lula

r di

gest

ion

wh

en a

lyo

som

e co

nta

in-

ing

dige

stiv

e en

zym

es m

erge

s w

ith

a

food

vac

uol

e

secr

eted

in

to t

he

mou

th b

y th

e sa

liva

ry g

lan

ds, b

egin

s th

e br

eak

-do

wn

of

star

ch i

nto

mal

tose

Th

e st

omac

h s

ecre

tes

gast

ric

juic

e,

a m

ixtu

re o

f di

gest

ive

enzy

me

and

hyd

roch

lori

c ac

id, (

HC

l), a

nd

serv

es a

var

iety

of

fun

ctio

ns

the

chem

ical

bre

akdo

wn

of

food

in

to s

mal

ler

mol

ecu

les

the

chem

ical

bre

akdo

wn

of

food

in

to s

mal

ler

mol

ecu

les

In m

ost

anim

als,

how

ever

, th

e fo

od i

nge

sted

is

too

larg

e to

be

en-

gulf

ed b

y in

divi

dual

cel

ls. T

hu

s,

food

is

firs

t di

gest

ed i

n a

gas

tro-

vasc

ula

r ca

vity

by

extr

acel

lula

r di

gest

ion

an

d th

en a

bsor

bed

by

indi

vidu

al c

ells

.

Mu

scu

lar

con

trac

tion

s

Pro

tein

s ar

e ch

emic

ally

bro

ken

do

wn

(di

gest

ed)

by t

he

enzy

me

peps

in

Sm

all

Inte

stin

e

Du

oden

um

: con

tin

-u

es t

he

dige

stio

n o

f st

arch

es, p

rote

ins,

fat

s,

nu

cleo

tide

s.

Bic

arbo

nat

e:

neu

tral

ize

the

acid

-it

y of

th

e ch

yme

Sec

reti

n: p

rodu

ced

by t

he

cell

s li

nin

g th

e du

odeu

m w

hen

fo

od e

nte

rs

Pan

crea

s: p

rodu

ces

vari

ous

enzy

mes

, in

clu

din

g tr

ypsi

n a

nd

chym

otry

psin

, lip

ase,

an

d pa

ncr

eati

c am

y-la

se

Wal

l of

th

e sm

all

inte

stin

e:so

urc

e of

var

iou

s en

zym

es t

o di

gest

pr

otei

ns

Sec

reti

n:

stim

ula

tes

the

pan

-cr

ease

to

prod

uce

bi

carb

onat

e

1920

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03.in

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21

-22

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/08

2:3

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AM

4/16

/08

2:3

5:12

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Page 12: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

Saliv

ary

amyla

se: b

egins

the

brea

kdow

n of

sta

rch

into

malt

ose

Saliv

ary

amyla

se: b

egins

the

brea

kdow

n of

sta

rch

into

malt

ose

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ary

amyl

ase:

beg

ins th

e br

eakd

own

of s

tarc

h int

o m

altos

e

Saliv

ary

amyl

ase:

beg

ins

the

brea

kdow

n of

sta

rch

into

malt

ose

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ary

amyl

ase

Saliv

ary

amyl

ase

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ary

amyl

ase

Saliv

ary

amyl

ase

SALIV

ARY

AMYL

ASE

SALIV

ARY

AMYL

ASE

Saliv

ary

amyl

ase

Saliv

ary

amyla

se: b

egins

the

brea

kdow

n of

sta

rch

into

malt

ose

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ary

amyla

se: b

egins

the

brea

kdow

n of

sta

rch

into

malt

ose

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ary

amyla

se: b

egins

the

brea

kdow

n of

sta

rch

into

malt

ose

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ary

amyla

se: b

egins

the

brea

kdow

n of

sta

rch

into

malt

ose

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ary

amyla

se: b

egins

the

brea

kdow

n of

sta

rch

into

malt

ose

Saliv

ary

amyl

ase:

beg

ins

the

brea

kdow

n of

SALIV

ARY AMYL

ASE

Saliv

ary

amyl

ase

Saliv

ary

amyl

ase

begi

ns th

e br

eakd

own

of s

tarc

h in

to m

altos

e

begi

ns th

e br

eakd

own

of

star

ch in

to m

altos

e

begin

s

th

e

brea

kdow

n

o f st

arch

into

m

altos

e

star

ch in

to m

altos

e

begi

ns th

e br

eakd

own

of

star

ch in

to m

altos

e

BEGINS T

HE BRE

AKDOWN

O

F STA

RTCH

Int

o

MALT

OSE

Saliv

ary

amyl

ase:

beg

ins

the

brea

kdow

n of

sta

rch

into

malt

ose

Saliv

ary

amyl

ase:

beg

ins th

e br

eakd

own

of s

tarc

h int

o m

altos

e

Saliv

ary

amyl

ase:

beg

ins

the

brea

kdow

n of

star

ch in

to m

altos

e

Saliv

ary

amyl

ase

SALIV

ARY

AMYL

ASE

SALIV

ARY

AMYL

ASE

begi

ns

th

e br

eakd

own

of

sta

rch

into

m

altos

e

Saliv

ary

amyl

ase:

beg

ins

the

brea

kdow

n of

sta

rch

into

malt

ose

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ary

amyl

ase:

beg

ins

the

brea

kdow

n of

sta

rch

into

malt

ose

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ary

amyl

ase:

beg

ins

the

brea

kdow

n of

sta

rch

into

malt

ose

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ary

amyl

ase:

beg

ins

the

brin

to m

altos

eea

kdow

n of

sta

rch

SALIV

ARY

AMYL

ASE

Saliv

ary

amyla

se: b

egins

the

brea

kdow

n of

sta

rch

into

malt

ose

BEGIN

S The

brea

kdow

n of s

tarch

into

maltos

e

Begin

s the

break

down o

f star

ch in

to malto

se

begins

the b

reakdo

wn of s

tarch

into m

altose

BEGIN

S The

brea

kdow

n of s

tarch

into

maltos

e

BEGIN

S The

brea

kdow

n of s

tarch

into

maltos

e

Saliv

ary

amyla

se: b

egins

the

brea

kdow

n of

sST

ARCH

INTO

MAL

TOSE

Saliv

ary

amyl

ase:

beg

ins

the

brea

kdow

n of

sta

rch

into

malt

ose

2122

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03.in

dd

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-24

4/16

/08

2:3

5:12

AM

4/16

/08

2:3

5:12

AM

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OR

DE

R:

Mea

n

Pu

rple

Egg

plan

ts

Saw

Sal

ty

Lem

ons

OR

DE

R:

Mou

th

Ph

aryn

x

Eso

phag

us

Sto

mac

h

Sm

all

Inte

stin

e

Lar

ge I

nte

stin

e

M P E S S L

2324

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-26

4/16

/08

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AM

4/16

/08

2:3

5:12

AM

Page 14: Cliffs AP Biology, 2nd Ed. vs.people.artcenter.edu/~jtsao1/m2/content/comm2_response... · 2008-04-17 · Ms. T waa ss m y e lev enent h g rad e BB iol ogy tee acha er. esi SheS re

Mo

uth

Ch

ewin

g!

Sta

rch

Mal

tose

Fo

od

bec

om

es B

olu

s,

and

Sw

allo

wed

.

Sto

ma

chG

astr

ic J

uic

em

ixtu

re o

f d

iges

tive

en

zym

e an

d

hy

dro

chlo

ric

acid

.

OU

TR

ectu

mF

eces

are

sto

red

at

th

e en

d o

f th

e la

rge

inte

stin

e, i

n

the

rect

um

, an

d

excr

eted

th

rou

gh

th

e an

us.

La

rge

Inte

stin

eC

olo

nR

eabs

orp

tio

n o

f w

ater

to

fo

rm s

oli

d w

aste

, or

fece

s.

Sm

all

Inte

stin

eD

iges

tio

n o

f st

arch

es

and

pro

tein

s.S

ecre

tin

- to

neu

tral

ize

acid

.

Ph

ary

nx

Ep

iglo

ttis

Blo

cks

the

trac

hea

so

mat

eria

l en

ters

on

ly

the

Eso

ph

agu

s.

Eso

ph

ag

us

Tu

be l

ead

ing

to

th

e st

om

ach

.M

ove

s by

Per

ista

lsis

(m

usc

ula

r co

ntr

acti

on

s)

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