Class I Class II Class Figures.pdf · PDF file • Galactose • Fructose SLC2A12/...

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Transcript of Class I Class II Class Figures.pdf · PDF file • Galactose • Fructose SLC2A12/...

  • Class I

    Class II

    Class III

  • NH2 COOH

    N

    1 2 3 4 5 7 8 6 12 11 10 9

    Extracellular

    Intracellular

    LL LL

    QLS

  • p m

    o l/

    o o

    cy te

    /m in

    0

    10

    20

    30

    40

    50

    60

    70

    NI

    GLUT12

    Na + buffer Na

    + - free

    ree

    buffer

  • A. Glucose 100 mM B. Glucose 100 mM

  • Related diseases

    • Obesity ? • Type II diabetes? • Cancer Physiological

    role

    Breast and Prostate Cancer

    Location

    Physiological role

    Adipose Tissue

    Skeletal Muscle

    Small intestine

    Unknown

    • Glucose • Galactose • Fructose

    Glucose SLC2A12/ GLUT12 Functional characteristics

    Equilibrative Concentrative

    Glucose H+

    or Na+ ?

    or

    Extracellular

    Intracellular Substrates

    Cytoplasmic Vesicles Translocation

    IRS-1

    PI3K PDKI

    GLUT4

    GLUT12

    Insulin response Glucose Insulin IR

    GLUT12 GLUT4

    Glucose Glycolytic metabolism

    Mitochondrion

    Pyruvate

    Lactate

    GLUT1 GLUT12 MCT1

    LDH-A Glycolysis

    H+

    Oxidative metabolism

    Glucose

disaccharides Sucrose: glucose+fructose (from suger cane or sugar beet), hydrolyzed by sucrase Lactose: galactose+glucose (from milk) hydrolyzed
disaccharides Sucrose: glucose+fructose (from suger cane or sugar beet), hydrolyzed by sucrase Lactose: galactose+glucose (from milk) hydrolyzed
Glucose Effect Galactose Enzymes of Escherichia ... three galenzymes, as well as fucose induction, is
Glucose Effect Galactose Enzymes of Escherichia ... three galenzymes, as well as fucose induction, is
Chemometrics and Intelligent Laboratory Systems lyze samples. D-glucose, D-xylose, mannose and galactose
Chemometrics and Intelligent Laboratory Systems lyze samples. D-glucose, D-xylose, mannose and galactose
Misfolding of galactose 1-phosphate uridylyltransferase ... Misfolding of galactose 1-phosphate uridylyltransferase
Misfolding of galactose 1-phosphate uridylyltransferase ... Misfolding of galactose 1-phosphate uridylyltransferase
PowerPoint-Pr¤ Skript 3__Enzyme_   Trypsin Fructose, Glucose Glucose Galactose,
PowerPoint-Pr¤ Skript 3__Enzyme_   Trypsin Fructose, Glucose Glucose Galactose,
21. Glucose is the major carbohydrate fuel for many cells. Galactose & Fructose are metabolized by conversion to a Glycolysis intermediate
21. Glucose is the major carbohydrate fuel for many cells. Galactose & Fructose are metabolized by conversion to a Glycolysis intermediate
Galactose conversion
Galactose conversion
Galactose-Depleted Xyloglucan Is Dysfunctional and Leads ... Galactose-Depleted Xyloglucan Is Dysfunctional
Galactose-Depleted Xyloglucan Is Dysfunctional and Leads ... Galactose-Depleted Xyloglucan Is Dysfunctional
Properties Mutants Galactose Taxis Transport galactose accumulatedontheordinate. Astraightline wasdrawnthroughthepoints
Properties Mutants Galactose Taxis Transport galactose accumulatedontheordinate. Astraightline wasdrawnthroughthepoints
Uridine Diphosphate Galactose-4-Epimerase - jbc. Diphosphate Galactose-4-Epimerase ... produced in this reaction can be reoxidized and ... Rate Law for UMP-dependent Reduction by Glucose
Uridine Diphosphate Galactose-4-Epimerase - jbc. Diphosphate Galactose-4-Epimerase ... produced in this reaction can be reoxidized and ... Rate Law for UMP-dependent Reduction by Glucose
BIOB111 SN11 Lecture Carbohydrates ¢â‚¬â€œ Examples: Glucose Two sugar unit compound Glucose Glucose Galactose
BIOB111 SN11 Lecture Carbohydrates ¢â‚¬â€œ Examples: Glucose Two sugar unit compound Glucose Glucose Galactose
Chemistry department/ third class Biochemistry/ Carbohydrates 10_26_35_PM.pdfCarbohydrates (like glucose)
Chemistry department/ third class Biochemistry/ Carbohydrates 10_26_35_PM.pdfCarbohydrates (like glucose)
ANNEX I SUMMARY OF PRODUCT 2010. 6. 3.¢  fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltase
ANNEX I SUMMARY OF PRODUCT 2010. 6. 3.¢  fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltase
DIABETES : THE GLUCOSE METABOLIC DISEASE Class 7 Dr. Pittler
DIABETES : THE GLUCOSE METABOLIC DISEASE Class 7 Dr. Pittler
ANNEX I SUMMARY OF PRODUCT fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltase
ANNEX I SUMMARY OF PRODUCT fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltase
1.5: Intro to Protein Networks. Lactase Lab Lactose sugar is composed of galactose and glucose Lactase enzyme breaks lactose into galactose and glucose
1.5: Intro to Protein Networks. Lactase Lab Lactose sugar is composed of galactose and glucose Lactase enzyme breaks lactose into galactose and glucose
SALMONELLAGALLINARUM PULLORUM' In arabinose, xylose, rhamnose, glucose, levulose, mannose, galactose
SALMONELLAGALLINARUM PULLORUM' In arabinose, xylose, rhamnose, glucose, levulose, mannose, galactose
Galactose metabolism disorders
Galactose metabolism disorders
ANEXO I RESUMO DAS CARACTER£†STICAS DO ... ... defici£¾ncia de lactase ou malabsor£§££o de glucose-galactose
ANEXO I RESUMO DAS CARACTER£†STICAS DO ... ... defici£¾ncia de lactase ou malabsor£§££o de glucose-galactose
Lactase Function: Enzyme that speeds up the breakdown of lactose (the main sugar found in milk) into glucose and galactose Polymer? Yes Subunits (monomers):
Lactase Function: Enzyme that speeds up the breakdown of lactose (the main sugar found in milk) into glucose and galactose Polymer? Yes Subunits (monomers):
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