CHEST PAIN AND SHORTNESS OF BREATHrfs.sirweb.org/wp-content/uploads/20150401_Abdul-Rahim... ·...
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CHEST PAIN AND SHORTNESS OF BREATH
Originally Posted: April 01, 2015
Resident(s): Osama Abdul-Rahim
Attending(s): Jeffrey Weinstein, Stephen Leschak, Paul Brady
Program/Dept(s): Einstein Healthcare Network, Philadelphia, PA
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CHIEF COMPLAINT & HPI
Chief Complaint and/or reason for consultation Acute onset chest pain and shortness of breath
History of Present Illness
36 y/o female initially presented with left lower extremity and groin pain after sensing a “pop”
Lower extremity US showed a left thigh mass found to be high grade sarcoma on biopsy with associated DVT extending from the CFV to the popliteal vein
Further workup revealed bilateral pulmonary emboli and mediastinal metastases with invasion of the pulmonary artery on the left
She is currently 1 week out from her 3rd cycle of chemotherapy
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RELEVANT HISTORY
Past Medical History Hypertension controlled with medication
Past Surgical History C-section
Family & Social History DM (grandmother) No tobacco, no EtOH, no other substance use
Medications Lisinopril
Allergies NKDA
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DIAGNOSTIC WORKUP
Previous chest CT (pre chemotherapy) Current chest CT (post chemotherapy)
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QUESTION 1
1) Where is the abnormality? (Answer on next slide)
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ANSWER TO QUESTION 1
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DIAGNOSIS
Left pulmonary artery pseudoaneurysm (PSA) Measures 1 cm across the base and 1 cm in depth No active hemorrhage
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INTERVENTION
Coiling was considered but the neck of the PSA was considered too wide for safe coil placement
No covered stent was available with the appropriate length and diameter
Therefore, a Wallstent was used as a flow diverter
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INTERVENTION
PSA
PE
Initial pulmonary angiogram Post Wallstent placement
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CLINICAL FOLLOW UP
Chest CTA three days after stenting showed the PSA had thrombosed
After one month the patient reported decreased chest pain and shortness of breath
She had no adverse events from stenting
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SUMMARY & TEACHING POINTS
36 y/o female with left thigh sarcoma and mediastinal metastases which eroded into the left main pulmonary artery
Chemotherapy induced regression of the metastasis resulted in a pseudoaneurysm of the left main pulmonary artery
Placement of a Wallstent wall stent to exclude the PSA allowed for adequate flow diversion and PSA thrombosis
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QUESTION 2
2) What are some of the treatment approaches for pseudoaneurysms?
A: Coil embolization
B: Stent placement
C: Thrombin injection
D: Ultrasound probe compression
E: All of the above
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CORRECT!
2) What are some of the treatment approaches for pseudoaneurysms?
A: Coil embolization (If the neck of the pseudoaneurysm is appropriately narrow then coiling the aneurysm sac is a good option)
B: Stent placement (Stent placement, as in this case will help redirect flow away from the aneurysm sac, more so if a covered stent is available)
C: Thrombin injection (This can be done with more superficial aneurysms, such as the femoral artery, but care must be taken that the thrombin does not travel systemically)
D: Ultrasound probe compression (Manual pressure with an ultrasound probe may be performed with more accessible pseudoaneurysms)
E: All of the above Continue with the Case
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SORRY, THAT’S INCORRECT.
2) What are some of the treatment approaches for pseudoaneurysms?
A: Coil embolization (If the neck of the pseudoaneurysm is appropriately narrow then coiling the aneurysm sac is a good option)
B: Stent placement (Stent placement, as in this case will help redirect flow away from the aneurysm sac, more so if a covered stent is available)
C: Thrombin injection (This can be done with more superficial aneurysms, such as the femoral artery, but care must be taken that the thrombin does not travel systemically)
D: Ultrasound probe compression (Manual pressure with an ultrasound probe may be performed with more accessible pseudoaneurysms)
E: All of the above
Continue with the Case
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QUESTION 3
3) Which of the following is NOT a cause of TRUE pulmonary artery pseudoaneurysms?
A: Chronic pulmonary hypertension
B: Behçet's disease
C: Birt-Hogg Dube syndrome
D: Marfan syndrome
E: Takayasu arteritis
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CORRECT!
3) Which of the following is NOT a cause of TRUE pulmonary artery pseudoaneurysms?
A: Chronic pulmonary hypertension
B: Behcet’s disease
C: Birt-Hogg Dube syndrome (An autosomal-dominant disorder that causes facial papules, bilateral renal tumors, and pulmonary cysts. Pulmonary pseudoaneurysms are not a characteristic of this syndrome)
D: Marfan syndrome
E: Takayasu arteritis
Continue with the Case
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SORRY, THAT’S INCORRECT.
3) Which of the following is NOT a cause of TRUE pulmonary artery pseudoaneurysms?
A: Chronic pulmonary hypertension
B: Behcet’s disease
C: Birt-Hogg Dube syndrome (An autosomal-dominant disorder that causes facial papules, bilateral renal tumors, and pulmonary cysts. Pulmonary pseudoaneurysms are not a characteristic of this syndrome)
D: Marfan syndrome
E: Takayasu arteritis
Continue with the Case
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REFERENCES & FURTHER READING
Lafita V, Borge MA, Demos TC. Pulmonary artery pseudoaneurysm: etiology, presentation, diagnosis, and treatment. Semin Intervent Radiol. 2007 Mar;24(1):119-23.
Dallaudière B, Hummel V, Pierre Laissy J. The use of covered stents for treatment of pulmonary artery pseudoaneurysms. J Vasc Interv Radiol. 2013 Feb;24(2):296-8.
Kaufman, J. and Lee, M. The Requisites: Vascular and Interventional Radiology, 2nd Ed. Philadelphia: Elsevier, 2014. Print.