ChemInform Abstract: The Nitro-Mannich Reaction and Its Application to the Stereoselective Synthesis...

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1999 addition reactions addition reactions O 0060 25 - 036 The Nitro-Mannich Reaction and Its Application to the Stereos- elective Synthesis of 1,2-Diamines. — Alkyl nitronate anions react with Pmb-imines (II) in the presence of Broensted acid to give β-nitro amines. In most cases, a high anti-selectivity up to 10:1 is observed. The moderately stable products (III) can be easily reduced and then deprotected with CAN to yield the diamines (VI) without erosion of diastereoselectivity. — (ADAMS, HARRY; ANDERSON, JAMES C.; PEACE, SIMON; PENNELL, ANDREW M. K.; J. Org. Chem. 63 (1998) 26, 9932-9934; Dep. Chem., Univ. Sheffield, Sheffield S3 7HF, UK; EN) 1

Transcript of ChemInform Abstract: The Nitro-Mannich Reaction and Its Application to the Stereoselective Synthesis...

Page 1: ChemInform Abstract: The Nitro-Mannich Reaction and Its Application to the Stereoselective Synthesis of 1,2-Diamines.

1999 addition reactions

addition reactionsO 0060

25 - 036The Nitro-Mannich Reaction and Its Application to the Stereos-elective Synthesis of 1,2-Diamines. — Alkyl nitronate anions reactwith Pmb-imines (II) in the presence of Broensted acid to give β-nitro amines.In most cases, a high anti-selectivity up to 10:1 is observed. The moderatelystable products (III) can be easily reduced and then deprotected with CAN toyield the diamines (VI) without erosion of diastereoselectivity. — (ADAMS,HARRY; ANDERSON, JAMES C.; PEACE, SIMON; PENNELL, ANDREWM. K.; J. Org. Chem. 63 (1998) 26, 9932-9934; Dep. Chem., Univ. Sheffield,Sheffield S3 7HF, UK; EN)

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The Boronic Acid Mannich Reaction

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ChemInform RxnFinder

ChemInform RxnFinder

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PROLINE CATALYZED ALDOL, MANNICH, AND MICHAEL …Sanyal.pdf · proline catalyzed aldol, mannich, and michael reactions: application of asymmetric organocatalysis sanjit sanyal department

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ChemInform Sheet A4 · 2013. 9. 13. · The ChemInform Reaction Library (CIRX) helps to deal with the enormous number of published reactions as it does not cover all information available

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Direct enantio- and diastereoselective Mannich …1 Direct enantio- and diastereoselective Mannich reactions of malonate and β-keto esters with N-Boc andN-Cbz aldimines catalysed

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tm Aromatic and Mannich polyols from Cardanol

tm Aromatic and Mannich polyols from Cardanol

l,3-Diphenylpropane-l,3-diamines, V1 2 1H-NMR- and IR … · 2013. 7. 13. · J SA 1,3-Diphenylpropane-1,3-diamines l,3-Diphenylpropane-l,3-diamines, V1'2^ 1H-NMR- and IR-Spectroscopic

l,3-Diphenylpropane-l,3-diamines, V1 2 1H-NMR- and IR … · 2013. 7. 13. · J SA 1,3-Diphenylpropane-1,3-diamines l,3-Diphenylpropane-l,3-diamines, V1'2^ 1H-NMR- and IR-Spectroscopic

Mannich Reaction

Mannich Reaction

DIAMINES AND CHEMICALS LIMITED CODE OF INTERNAL … and Conduct for... · 2019-12-27 · 1.4 “Company” means Diamines and Chemicals Limited. 1.5 "Compliance Officer" means Company

DIAMINES AND CHEMICALS LIMITED CODE OF INTERNAL … and Conduct for... · 2019-12-27 · 1.4 “Company” means Diamines and Chemicals Limited. 1.5 "Compliance Officer" means Company

Diastereoselective Regiodivergent Mannich Versus Tandem ...

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