ChemInform Abstract: Synthesis of Hydantoin Analogues of (2S,3R,4S)-4-Hydroxyisoleucine with...

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ChemInform 2008, 39, issue 48 ©WlLEY-VCH Verlag GmbH & Co. KGaA, Weinheim www.cheminform.wiley-vch.de Hydantoin derivatives R 0210 Synthesis of Hydantoin Analogues of (2S,3R,4S)-4-Hydroxyisoleucine with Insuli- notropic Properties. — The first synthesis of optically pure hydantoin (V), an ana- logue of (2R,3R,4S)-4-hydroxyisoleucine, is described. Compound (V) is stable in acidic environment and stimulates the insulin secretion. — (SERGENT, D.; WANG, Q.; SASAKI, N. A.; OUAZZANI*, J.; Bioorg. Med. Chem. Lett. 18 (2008) 15, 4332-4335; Inst. Chim. Subst. Nat., CNRS, F-91198 Gif-sur-Yvette, Fr.; Eng.) — H. Toeppel 48- 123

Transcript of ChemInform Abstract: Synthesis of Hydantoin Analogues of (2S,3R,4S)-4-Hydroxyisoleucine with...

Page 1: ChemInform Abstract: Synthesis of Hydantoin Analogues of (2S,3R,4S)-4-Hydroxyisoleucine with Insulinotropic Properties.

www.cheminform.wiley-vch.de

Hydantoin derivativesR 0210 Synthesis of Hydantoin Analogues of (2S,3R,4S)-4-Hydroxyisoleucine with Insuli-

notropic Properties. — The first synthesis of optically pure hydantoin (V), an ana-logue of (2R,3R,4S)-4-hydroxyisoleucine, is described. Compound (V) is stable in acidic environment and stimulates the insulin secretion. — (SERGENT, D.; WANG, Q.; SASAKI, N. A.; OUAZZANI*, J.; Bioorg. Med. Chem. Lett. 18 (2008) 15, 4332-4335; Inst. Chim. Subst. Nat., CNRS, F-91198 Gif-sur-Yvette, Fr.; Eng.) — H. Toeppel

48- 123

ChemInform 2008, 39, issue 48 ©WlLEY-VCH Verlag GmbH & Co. KGaA, Weinheim

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Biological activity of well defined hydantoin …...Biological activity of well defined hydantoin derivatives on efflux pump systems of bacteria and cancer cells Miguel José Simas

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Tổng hợp và thử hoạt tính kháng tế bào ung thư của 5 -(4''-bromobenzyliden) hydantoin và một số dẫn chất base mannich.pdf

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Enteroendocrine K and L cells in healthy and type 2 …...hormones: glucose-dependent insulinotropic polypeptide (GIP) from enteroendocrine K cells, and glucagon-like peptide-1 (GLP-1)

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FASD: DIAGNOSIS INFORMED CARE · injury, delirium, dementia), another known teratogen (e.g., fetal hydantoin syndrome), a genetic condition (e.g., Williams syndrome, Down syndrome,

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Revised Form-1 Finalenvironmentclearance.nic.in/writereaddata/Online/... · Charge Hydantoin, Glycine, Acetone, Sodium hydroxide and DM water in SS Reactor, Heat the reaction mass

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Lipolytic, Energy Expenditure, and Insulinotropic Effects of HM12525A: A Novel Long-Acting GLP-1/Glucagon Dual Agonist SY Jung 1,, YJ Park 1, JK Kim 1,

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DMDM Hydantoin (DMDMH) Product-type 13 (Metalworking Fluids) - Public/Library... · Directive 98/8/EC concerning the placing biocidal . products on the market . Inclusion of active

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