ChemInform Abstract: Synthesis of 1H-Imidazo[1,2-b]1,2,4-triazol-6-amines via Multicomponent...

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2008 Triazole derivatives R 0280 Synthesis of 1H-Imidazo[1,2-b]1,2,4-triazol-6-amines via Multicomponent Reac- tion. — A simple and efficient method for the synthesis of bioactive imidazotriazoles (32 examples) is reported. Compounds (IVa), (IVc), (IVd), and (IVe) display good cy- totoxic activities. Antibacterial effects are only observed for derivative (IVg). — (HUANG, Y.; HU, X.-Q.; SHEN, D.-P.; CHEN, Y.-F.; XU, P.-F.; Mol. Diversity 11 (2007) 2, 73-80; State Key Lab. Appl. Org. Chem., Lanzhou Univ., Lanzhou, Gansu 730000, Peop. Rep. China; Eng.) — Bartels 14- 151

Transcript of ChemInform Abstract: Synthesis of 1H-Imidazo[1,2-b]1,2,4-triazol-6-amines via Multicomponent...

2008

Triazole derivativesR 0280 Synthesis of 1H-Imidazo[1,2-b]1,2,4-triazol-6-amines via Multicomponent Reac-

tion. — A simple and efficient method for the synthesis of bioactive imidazotriazoles (32 examples) is reported. Compounds (IVa), (IVc), (IVd), and (IVe) display good cy-totoxic activities. Antibacterial effects are only observed for derivative (IVg). — (HUANG, Y.; HU, X.-Q.; SHEN, D.-P.; CHEN, Y.-F.; XU, P.-F.; Mol. Diversity 11 (2007) 2, 73-80; State Key Lab. Appl. Org. Chem., Lanzhou Univ., Lanzhou, Gansu 730000, Peop. Rep. China; Eng.) — Bartels

14- 151