ChemInform Abstract: Phosphodiesterase 4 Isoenzyme Inhibitory Activity of 3-Phenylxanthines and...

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2001 purine derivatives purine derivatives R 0540 28 - 159 Phosphodiesterase 4 Isoenzyme Inhibitory Activity of 3- Phenylxanthines and 4-Phenyl[i]condensed-purines. — Based on known structure–activity relationship investigations, the title novel com- pounds such as (V), (IX), and (X) are synthesized. Some of them exhibit potent and selective PDE 4 inhibitory activity. — (SUZUKI, HIROKAZU; SAWANISHI, HIROYUKI; YAMAMOTO, KENJI; YOKOGAWA, KOICHI; MIYAMOTO, KEN-ICHI; Chem. Pharm. Bull. 49 (2001) 2, 188-191; Dep. Synth. Chem., Fac. Pharm. Sci., Hokuriku Univ., Kanazawa 920, Japan; EN) 1

Transcript of ChemInform Abstract: Phosphodiesterase 4 Isoenzyme Inhibitory Activity of 3-Phenylxanthines and...

Page 1: ChemInform Abstract: Phosphodiesterase 4 Isoenzyme Inhibitory Activity of 3-Phenylxanthines and 4-Phenyl[i]condensed-purines.

2001 purine derivatives

purine derivativesR 0540

28 - 159Phosphodiesterase 4 Isoenzyme Inhibitory Activity of 3-Phenylxanthines and 4-Phenyl[i]condensed-purines. — Basedon known structure–activity relationship investigations, the title novel com-pounds such as (V), (IX), and (X) are synthesized. Some of them exhibitpotent and selective PDE 4 inhibitory activity. — (SUZUKI, HIROKAZU;SAWANISHI, HIROYUKI; YAMAMOTO, KENJI; YOKOGAWA, KOICHI;MIYAMOTO, KEN-ICHI; Chem. Pharm. Bull. 49 (2001) 2, 188-191; Dep.Synth. Chem., Fac. Pharm. Sci., Hokuriku Univ., Kanazawa 920, Japan; EN)

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ภาพนิ่ง 1 - thaipedlung.org fileEvidence of myocardial damage • Creatinine kinase–MB isoenzyme (CK-MB) • Lactate dehydrogenase isoenzyme 1 • Troponin I, Troponin

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Cyclic AMP-specific phosphodiesterase, PDE8A1, is activated by …eprints.gla.ac.uk/65849/1/65849.pdf · 2014. 7. 24. · Cyclic AMP-specific phosphodiesterase, PDE8A1, is activated

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Title: Aortic Stenosis and PhosphodiEsterase Type 5 ...€¦ · Aortic Stenosis and PhosphodiEsterase Type 5 InhibitioN (ASPEN) PI: Lindman, Brian R. Washington University School

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Phosphodiesterase-8A binds to and regulates Raf-1 kinase

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Effects of Rolipram (a New Selective Phosphodiesterase 4

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ChemInform Sheet A4 · 2013. 9. 13. · The ChemInform Reaction Library (CIRX) helps to deal with the enormous number of published reactions as it does not cover all information available

ChemInform Sheet A4 · 2013. 9. 13. · The ChemInform Reaction Library (CIRX) helps to deal with the enormous number of published reactions as it does not cover all information available

Effects of phosphodiesterase 3A modulation on murine ......RESEARCH Open Access Effects of phosphodiesterase 3A modulation on murine cerebral microhemorrhages Rachita K. Sumbria1,2,

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Effects of Phosphodiesterase Type 5 Inhibition on …circ.ahajournals.org/content/suppl/2012/03/20/... · Effects of Phosphodiesterase Type 5 Inhibition on ... (mL/min/1.73m2)* 55

Effects of Phosphodiesterase Type 5 Inhibition on …circ.ahajournals.org/content/suppl/2012/03/20/... · Effects of Phosphodiesterase Type 5 Inhibition on ... (mL/min/1.73m2)* 55