ChemInform Abstract: Highly N2-Selective Palladium-Catalyzed Arylation of 1,2,3-Triazoles.
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ChemInform 2012, 43, issue 07 © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Triazole derivatives R 0280 DOI: 10.1002/chin.201207114 Highly N 2 -Selective Palladium-Catalyzed Arylation of 1,2,3-Triazoles. — Aryla- tion of 1,2,3-triazoles with aryl halides is achieved with excellent N2-selectivity in the in the presence of a novel Pd—biphenylphosphine catalyst. The reaction tolerates var- ious functional groups on the aromatic ring and even triazoles bearing various substi- tuents at the 4-position can be employed. Regioselectivity is lost for 4,5-disubstituted triazole (VII). — (UEDA, S.; SU, M.; BUCHWALD*, S. L.; Angew. Chem., Int. Ed. 50 (2011) 38, 8944-8947, http://dx.doi.org/10.1002/anie.201103882 ; Dep. Chem., MIT, Cambridge, MA 02139, USA; Eng.) — S. Adam 07- 114
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Transcript of ChemInform Abstract: Highly N2-Selective Palladium-Catalyzed Arylation of 1,2,3-Triazoles.
Triazole derivativesR 0280 DOI: 10.1002/chin.201207114
Highly N2-Selective Palladium-Catalyzed Arylation of 1,2,3-Triazoles. — Aryla-tion of 1,2,3-triazoles with aryl halides is achieved with excellent N2-selectivity in the in the presence of a novel Pd—biphenylphosphine catalyst. The reaction tolerates var-ious functional groups on the aromatic ring and even triazoles bearing various substi-tuents at the 4-position can be employed. Regioselectivity is lost for 4,5-disubstituted triazole (VII). — (UEDA, S.; SU, M.; BUCHWALD*, S. L.; Angew. Chem., Int. Ed. 50 (2011) 38, 8944-8947, http://dx.doi.org/10.1002/anie.201103882 ; Dep. Chem., MIT, Cambridge, MA 02139, USA; Eng.) — S. Adam
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ChemInform 2012, 43, issue 07 © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
