ChemInform Abstract: Efficient Chemoenzymatic Synthesis of Sialyl Tn-Antigens and Derivatives.

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ChemInform 2011, 42, issue 49 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Carbohydrates U 0500 DOI: 10.1002/chin.201149190 Efficient Chemoenzymatic Synthesis of Sialyl Tn-Antigens and Derivatives. — N-terminal and C-terminal truncated recombinant α2↔6-sialyltransferase cloned from Photobacterium sp. JH-ISH-224, Psp2,6ST(15↔501)-His6, was shown to be an effi- cient catalyst for the one-pot three-enzyme synthesis of sialyl Tn (STn) antigens and derivatives containing natural and non-natural sialic acid forms. — (DING, L.; YU, H.; LAU, K.; LI, Y.; MUTHANA, S.; WANG, J.; CHEN*, X.; Chem. Commun. (Cambridge) 47 (2011) 30, 8691-8693, http://dx.doi.org/10.1039/c1cc12732b ; Coll. Sci., Northwest A & F Univ., Yangling 712100, Shaanxi, Peop. Rep. China; Eng.) — M. Paetzel 49- 190

Transcript of ChemInform Abstract: Efficient Chemoenzymatic Synthesis of Sialyl Tn-Antigens and Derivatives.

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CarbohydratesU 0500 DOI: 10.1002/chin.201149190

Efficient Chemoenzymatic Synthesis of Sialyl Tn-Antigens and Derivatives. — N-terminal and C-terminal truncated recombinant α2↔6-sialyltransferase cloned from Photobacterium sp. JH-ISH-224, Psp2,6ST(15↔501)-His6, was shown to be an effi-cient catalyst for the one-pot three-enzyme synthesis of sialyl Tn (STn) antigens and derivatives containing natural and non-natural sialic acid forms. — (DING, L.; YU, H.; LAU, K.; LI, Y.; MUTHANA, S.; WANG, J.; CHEN*, X.; Chem. Commun. (Cambridge) 47 (2011) 30, 8691-8693, http://dx.doi.org/10.1039/c1cc12732b ; Coll. Sci., Northwest A & F Univ., Yangling 712100, Shaanxi, Peop. Rep. China; Eng.) — M. Paetzel

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ChemInform 2011, 42, issue 49 © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

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