ChemInform Abstract: Crystal Structures and Reactivity of 3a,5a,8a,10a-Tetraazaperhydropyrene...
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2000 multi-membered N-heterocycles multi-membered N-heterocycles R 0690 29 - 126 Crystal Structures and Reactivity of 3a,5a,8a,10a- Tetraazaperhydropyrene Derivatives. An Alternative Approach to Selective Nitrogen Alkylation of 1,4,8-11-Tetraazacyclotetradecane (Cyclam). — An alternative route for the synthesis of 1,8-disubstituted cyclam derivatives like (IV) and (VII) from the cis-aminal (I) is described. The trans-aminal (VIII) is also synthesized but cannot be used for the preparation of cyclam derivatives due to exceptional stability of the aminal bridge [X-ray structure determination for a series of cyclam derivatives]. — (KOTEK, JAN; HERMANN, PETR; VOJTISEK, PAVEL; ROHOVEC, JAN; LUKES, IVAN; Collect. Czech. Chem. Commun. 65 (2000) 2, 243-266; Dep. Inorg. Chem., Charles Univ., CZ-128 40 Prague 2, Czech Republic; EN) 1
Transcript of ChemInform Abstract: Crystal Structures and Reactivity of 3a,5a,8a,10a-Tetraazaperhydropyrene...
2000 multi-membered N-heterocycles
multi-membered N-heterocyclesR 0690
29 - 126Crystal Structures and Reactivity of 3a,5a,8a,10a-Tetraazaperhydropyrene Derivatives. An Alternative Approachto Selective Nitrogen Alkylation of 1,4,8-11-Tetraazacyclotetradecane(Cyclam). — An alternative route for the synthesis of 1,8-disubstitutedcyclam derivatives like (IV) and (VII) from the cis-aminal (I) is described. Thetrans-aminal (VIII) is also synthesized but cannot be used for the preparationof cyclam derivatives due to exceptional stability of the aminal bridge [X-raystructure determination for a series of cyclam derivatives]. — (KOTEK, JAN;HERMANN, PETR; VOJTISEK, PAVEL; ROHOVEC, JAN; LUKES, IVAN;Collect. Czech. Chem. Commun. 65 (2000) 2, 243-266; Dep. Inorg. Chem.,Charles Univ., CZ-128 40 Prague 2, Czech Republic; EN)
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