ChemInform Abstract: Bis(methylphosphonic acid) Derivatives of 1,4,8,11-Tetraazacyclotetradecane...

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2001 multi-membered N-heterocycles multi-membered N-heterocycles R 0690 05 - 133 Bis(methylphosphonic acid) Derivatives of 1,4,8,11- Tetraazacyclotetradecane (Cyclam). Synthesis, Crystal and Molec- ular Structures, and Solution Properties. A suitable route for the synthesis of mono- and bis(methylphosphonic acid) derivatives of cyclam by Mannich reaction followed by removal of the protecting groups is reported. Crystal and molecular structure investigations show strong hydrogen bonds even in aqueous solution. — (KOTEK, JAN; VOJTISEK, PAVEL; CISAROVA, IVANA; HERMANN, PETR; JURECKA, PETR; ROHOVEC, JAN; LUKES, IVAN; Collect. Czech. Chem. Commun. 65 (2000) 8, 1289-1316; Dep. Inorg. Chem., Charles Univ., CZ-128 40 Prague 2, Czech Republic; EN) 1

Transcript of ChemInform Abstract: Bis(methylphosphonic acid) Derivatives of 1,4,8,11-Tetraazacyclotetradecane...

Page 1: ChemInform Abstract: Bis(methylphosphonic acid) Derivatives of 1,4,8,11-Tetraazacyclotetradecane (Cyclam). Synthesis, Crystal and Molecular Structures, and Solution Properties.

2001 multi-membered N-heterocycles

multi-membered N-heterocyclesR 0690

05 - 133Bis(methylphosphonic acid) Derivatives of 1,4,8,11-Tetraazacyclotetradecane (Cyclam). Synthesis, Crystal and Molec-ular Structures, and Solution Properties. — A suitable route forthe synthesis of mono- and bis(methylphosphonic acid) derivatives of cyclamby Mannich reaction followed by removal of the protecting groups is reported.Crystal and molecular structure investigations show strong hydrogen bonds evenin aqueous solution. — (KOTEK, JAN; VOJTISEK, PAVEL; CISAROVA,IVANA; HERMANN, PETR; JURECKA, PETR; ROHOVEC, JAN; LUKES,IVAN; Collect. Czech. Chem. Commun. 65 (2000) 8, 1289-1316; Dep. Inorg.Chem., Charles Univ., CZ-128 40 Prague 2, Czech Republic; EN)

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