ChemInform Abstract: A Selective Method for the Preparation of Aliphatic Methyl Esters in the...
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1999 esterification, ester hydrolysis esterification, ester hydrolysis O 0310 07 - 074 A Selective Method for the Preparation of Aliphatic Methyl Esters in the Presence of Aromatic Carboxylic Acids. — A mixture of 2,2-dimethoxypropane and methanol in the presence of catalytic HCl, generated in situ from TmsCl, is found to be an efficient reagent for the selective monoes- terification of aliphatic carboxylic acids in the presence of aromatic ones. A successful application of the method to the synthesis of various aliphatic esters is presented. Aromatic and heteroaromatic acids [cf. (XVI)] remain nearly unchanged, thus proving the results obtained with dicarboxylic acids of type (I). — (RODRIGUEZ, A.; NOMEN, M.; SPUR, B. W.; GODFROID, J. J.; Tetrahedron Lett. 39 (1998) 47, 8563-8566; Dep. Cell Biol., Univ. Med. Dent., Stratford, NJ 08084, USA; EN) 1
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Transcript of ChemInform Abstract: A Selective Method for the Preparation of Aliphatic Methyl Esters in the...
1999 esterification, ester hydrolysis
esterification, ester hydrolysisO 0310
07 - 074A Selective Method for the Preparation of Aliphatic Methyl Estersin the Presence of Aromatic Carboxylic Acids. — A mixture of2,2-dimethoxypropane and methanol in the presence of catalytic HCl, generatedin situ from TmsCl, is found to be an efficient reagent for the selective monoes-terification of aliphatic carboxylic acids in the presence of aromatic ones. Asuccessful application of the method to the synthesis of various aliphatic estersis presented. Aromatic and heteroaromatic acids [cf. (XVI)] remain nearlyunchanged, thus proving the results obtained with dicarboxylic acids of type(I). — (RODRIGUEZ, A.; NOMEN, M.; SPUR, B. W.; GODFROID, J. J.;Tetrahedron Lett. 39 (1998) 47, 8563-8566; Dep. Cell Biol., Univ. Med. Dent.,Stratford, NJ 08084, USA; EN)
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1999 esterification, ester hydrolysis
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