Chemical Basis for Life
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Transcript of Chemical Basis for Life
Chemical Basis for Life
And Biochemistry
Chemistry is important to biologists because all of the life activities in our cells that keep us alive are the result of chemical reactions.◦ Matter—anything that has mass and takes up
space.◦ Elements—found on Periodic Table. Cannot be
broken down into simpler kinds of matter.◦ HONC (Honk)—hydrogen, oxygen, nitrogen,
carbon. These are the most important elements in living things.
Chemistry of Life
Atom—simplest particle of an element that keeps all the properties of that element.
Parts of an atom◦ Protons—positive charge◦ Neutrons—no charge◦ Electrons—negative charge
Atoms
Inside Nucleus
Orbit Nucleus
The atomic number is the number of protons in an atom
The atomic mass is the number of protons plus the number of neutrons.
The number of electrons in an atom is the same as the number or protons giving it a net charge of zero.
Isotopes—atoms of the same element with different number of neutrons.
Isotopes
Compounds Compounds —atoms of two or more
elements joined by chemical bonds.◦ Examples: H2O NaCl C6H12O6◦ Three models below show a water molecule
http://www.lionden.com/graphics/AP/Water1.gif
Stick model Bohr model Electron Cloud model
Chemical bonds are attractive forces that hold atoms together. They form so that elements can become more stable by filling their outer energy levels.
Chemical Bonds
Covalent Bonds—two atoms SHARE electrons
Types of Chemical Bonds
Carbon has the ability to form multiple covalent bonds
Carbon has 4 electrons in its outer shell. The shell can hold 8. Carbon needs 4 more electrons to become stable. This can result in big biological molecules based around chains of carbon atoms.
http://www.chemistrydaily.com/chemistry/upload/d/d9/Covalent.png
http://t1.gstatic.com/images?q=tbn:ANd9GcTDsTGWMhdl6_3izM7K7RCw6b5ueLWXpacSg91FXY8Tt6PoObw&t=1&usg=__fkitOKpfQ768Lo6SF7eDzZ0qobs=
Many complex biological molecules will be formed using double and triple covalent bonds.
Double —share 2 pair of electrons Triple —share 3 pair of electrons
Ethane
Ethylene
Acetylene
Ionic Bonds—atoms LOSE or GAIN electrons creating charges that attract each other.◦ SALTS!!!!
Energy and Chemical Reactions Chemical reactions occur when one or
more substances change to produce one or more new substances.
Chemical equations show what happens during the reaction
Reactants on left Products on right 6CO2 + 6 H2O C6H12O6 + 6O2 +energy
Reaction Speed Most reactions need the
addition of energy before they will begin.
Activation Energy —energy required for a reaction to begin
Catalyst —speed up chemical reactions by lowering the activation energy required.◦ Enzymes are common catalysts
in living things◦ They remain unchanged
throughout the reaction.http://xnet.rrc.mb.ca/davidb/photogallery/activationenergy1.gif
Endothermic and Exothermic Reactions Endothermic reactions
result in a net absorption of energy
Exothermic reactions results in the net release of energy
Oxidation Reduction Reactions Also called Redox Reactions
◦ Electrons are transferred between atoms◦ Oxidation reaction —a reactant loses electrons
resulting in a positive charge Example—Na loses an electron to become more
stable creating a sodium ion (Na+)◦ Reduction reaction —a reactant gains
electrons resulting in a negative charge Example—Chlorine gains an electron to become
more stable creating a chlorine ion (Cl-)◦ The two always occur together. One reactant
gives up what the other needs.
Water and Solutions Water’s chemical structure is
important in its vital role in life.
http://www.lenntech.com/images/Water%20molecule.jpg http://www.ci.rockford.il.us/uploadedImages/government/PublicWorks/Water/willing
%20water%20color.jpg
Water is POLAR◦ Electrons in the covalent bond are not shared
equally. Results in a partial negative charge on the oxygen end and a partial positive charge on the hydrogen end.
Properties of Water
Being polar allows water to:◦ Dissolve many substances◦ Form hydrogen bonds with other water
molecules creating: Cohesion Surface Tension Adhesion Capillarity High heat capacity Less density when water freezes (ice floats!!)
Solutions Solution —mixture in which one or more
substances are uniformly distributed in another substance.◦ Solute —dissolved substance◦ Solvent —substance in which the solute is
dissolved◦ Concentration —amount of solute dissolved in a
fixed amount of solution◦ Saturated Solution —no more solute can be
dissolved
Ionization of Water Water molecules can collide and break each
other apart H2O H+ + OH-
OH- is known as the hydroxide ion
Free H+ ions react with water molecules: H+ + H2O H3O+
H3O+ is known as the hydronium ion
Acids and Bases Acid —solution in which the number of
hydronium ions is greater than the number of hydroxide ions◦ They have a value BELOW 7 on the pH scale.
Base —solution in which the number of hydroxide ions is greater than the number of hydronium ions (Alkaline)◦ They have a value ABOVE 7 on the pH scale
Carbon—element of life◦ Organic compounds—contain carbon (and
hydrogen)◦ Can form 4 covalent bonds with other elements
so it is the backbone of all organic compounds.
Biochemistry
Various functional groups can be attached to these carbon backbones. These groups determine how these molecules will react with other molecules.
Functional groups can be seen on the following chart:
Functional Groups
Hydroxyl(Alcohols)
Functional Group Structural Formula Example
-OH
Carbonyl (on end)(Aldehydes) - C=O
H
Carbonyl (in middle)(Ketone) C
O
Carboxyl(Organic Acids) COOH
Amino(Amino Acids) NH2
Phosphate(Nucleic Acids) PO4
3-
Large Carbon Molecules The building of large molecules occurs as follows:
◦ Monomers —small, simple carbon molecules
◦ Polymers —consists of repeated, linked monomers
◦ Macromolecules —large polymers: (Carbohydrates, lipids, proteins, nucleic acids)
http://kenpitts.net/bio/human_anat/monomer.jpg
Condensation Reactions Polymers form during condensation
reactions In these reactions; water is released
Example: Glucose and Fructose combine to form Sucrose
Hydrolysis Polymers break down by a hydrolysis
reaction In these reactions; water is used
http://imcurious.wikispaces.com/file/view/hydrolysis_reaction.jpg/113609729/hydrolysis_reaction.jpg
Adenosine Triphosphate (ATP ) —the most important energy currency molecule of cells.◦ Made of Adenine; Ribose (a sugar) and 3
phosphate groups
The Energy Molecule: ATP
The Hydrolysis of ATP is used by the cell to provide the energy needed to drive chemical reactions.
http://kentsimmons.uwinnipeg.ca/cm1504/atp.htm
-ATP can lose its end phosphate which releases the energy stored in it. and makes adenosine diphosphate (ADP).-This energy is used to do work in the cell.-Adding the phosphate back to make ATP requires that we add energy
The Molecules of Life Four main groups of organic
compounds:◦ Carbohydrates◦ Proteins◦ Lipids ◦ Nucleic Acids
http://ez002.k12.sd.us/Chapter%20One%20Science.htm
Used for energy Three types:
◦ Monosaccharides (glucose and fructose)
◦ Disaccharides (sucrose)
◦ Polysaccharides (glycogen, starch and cellulose)
Carbohydrates
Structure is too complex to show
Made of chains of amino acids held together by peptide bonds.◦ Dipeptides (two amino acids)◦ Polypeptides (long chains of amino acids) that
fold and bend into proteins.
Proteins
Typical amino acid
Form by condensationreactions.
Enzymes —special types of proteins that act as catalysts
Lipids are fats. Used for energy Nonpolar Fatty acids bonded to other molecules
Lipids
Saturated Fatty Acids —each carbon is covalently bonded to four atoms (NO DOUBLE BONDS)
Unsaturated Fatty Acids —not all carbons are bonded to four other atoms (HAS DOUBLE BONDS)
http://www.biology.lsu.edu/introbio/Link2/fatty%20acids.gif
Classes of Lipids Triglycerides (fats) —three molecules of fatty acid
joined to one molecule of glycerol.◦ Saturated triglycerides —the 3 fatty acids are saturated:
hard at room temp: found in butter and red meat: “bad fats”◦ Unsaturated triglycerides —the 3 fatty acids are
unsaturated: soft at room temp: found in plant seeds: “good fats”
Phospholipids —two fatty acids joined to glycerol. They also have a phosphate group.◦ Important part of all cell membranes
Waxes —fatty acid chain joined to an alcohol chain: waterproof: form protective layers in plants and animals
Steroids —four fused carbon rings with a functional group: include many hormones and cholesterol
Include DNA and RNA Information
molecules Made of repeating
monomers called nucleotides.◦ Phosphate, pentose
sugar, nitrogenous base.
Nucleic Acids