CHAPTER 9 Therapeutic Agents - Avian...

102
Editors’ Disclaimer: Every attempt has been made to ensure accurate citation of dosages and references. However, the reader must assume ultimate responsibility for the use of any medica- tion. Indications and usage listed are as per the refer- ence(s) cited, and may not bear pharmacodynamic data verifying efficacy or safety. Dosages that vary significantly (by a factor of 50x or greater) from other empirical or pharmacokinetic stud- ies may be omitted from the table, but may be found in the references. No claims to efficacy or safety are intended or implied. See abbreviations key at the end. 9 Therapeutic Agents KEATH L. MARX, DVM CHAPTER

Transcript of CHAPTER 9 Therapeutic Agents - Avian...

Page 1: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Editors’ Disclaimer:

Every attempt has been made to ensure accurate citation

of dosages and references. However, the reader must

assume ultimate responsibility for the use of any medica-

tion. Indications and usage listed are as per the refer-

ence(s) cited, and may not bear pharmacodynamic data

verifying efficacy or safety.

Dosages that vary significantly (by a factor of 50x or

greater) from other empirical or pharmacokinetic stud-

ies may be omitted from the table, but may be found in

the references.

No claims to efficacy or safety are intended or implied.

See abbreviations key at the end.

9

TherapeuticAgentsKKEEAATTHH LL.. MMAARRXX,, DDVVMM

CHAPTER

Page 2: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I242

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Acep

rom

azin

e M

ale

ate

A

vian

0.

5-1

IM

Q

D

E

53, 7

04

Add k

etam

ine

Ace

pro

maz

ine

Mal

eate

C

asso

war

y, D

oub

le-w

attl

ed

0.63

IM

P

RN

G

44

7 A

dd e

torp

hin

e

Ace

pro

maz

ine

Mal

eate

H

awk

2.0

N

L

PR

N

D

1401

A

dd k

etam

ine

Ace

pro

maz

ine

Mal

eate

O

stri

ch

0.16

-0.1

9 IM

P

RN

B

44

7 A

dd e

torp

hin

e

Ace

pro

maz

ine

Mal

eate

O

stri

ch

25 M

G T

D

NL

P

RN

D

14

01

Add e

torp

hin

e +

xyl

azin

e

Ace

pro

maz

ine

Mal

eate

O

wl

2.0

NL

P

RN

D

14

01

Add k

etam

ine

Ace

pro

maz

ine

Mal

eate

R

apto

r 2.

2

IM

PR

N

E

1386

A

dd k

etam

ine

Ace

pro

maz

ine

Mal

eate

R

atit

e 0.

25-0

.5

IM

PR

N

G

418

Ace

pro

maz

ine

Mal

eate

R

atit

e 0.

1-0.

2 IV

P

RN

G

41

8

Acety

lcyst

ein

e

Am

azo

n, R

ed L

ore

d

22 m

g/m

l N

ebuliz

e Q

D

G

700

10%

co

nce

ntr

atio

n

Acti

vate

d C

harc

oal

Avi

an

52 P

O

On

ce

E

1526

G

ive

afte

r fi

rst

do

se o

f fl

uid

s fo

r o

iled b

irds

Act

ivat

ed C

har

coal

A

vian

2-

8 g/

kg

PO

N

L

E

1554

, 174

5

Act

ivat

ed C

har

coal

Psi

ttac

ine

2-8

g/kg

PO

PR

NE

1240

Ab

sorb

inge

sted

to

xin

s

Act

ivat

ed C

har

coal

Rap

tor

2-10

g/kg

PO

PR

NE

1400

An

tidia

rrh

eal,

abso

rbs

toxi

ns

Acyclo

vir

Avi

an1

g/L

wat

erD

rin

kN

LA

435

Acy

clo

vir

Avi

an

400

mg/

kg f

oo

d

Fee

d

On

ce

A

435

Acy

clo

vir

Avi

an

80

PO

T

ID

E

1470

, 147

3 F

or

her

pes

viru

s, (

also

ref

# 1

560,

165

0)

Acy

clo

vir

Avi

an

25

IM

NL

G

43

5

Acy

clo

vir

Avi

an

40

IM

TID

G

13

06

Fo

r P

ach

eco

's d

isea

se

Acy

clo

vir

Avi

an

80

PO

T

ID

G

1306

F

or

Pac

hec

o's

dis

ease

Acy

clo

vir

Avi

an

330

G

avag

e B

ID

G

1352

Acy

clo

vir

Avi

an

0.4

g/L

D

rin

k Q

D

G

1352

Acy

clo

vir

Ch

icke

n

10

IM

QD

B

43

5

Acy

clo

vir

Mac

aw

80

PO

T

ID

A

435

Acy

clo

vir

Par

akee

t, Q

uak

er

40

IM

TID

A

10

60

Acy

clo

vir

Par

akee

t, Q

uak

er1

g/L

fee

dF

eed

QD

A10

60C

han

ge f

eed B

ID

Acy

clo

vir

Psi

ttac

ine

0.4

g/L

wat

erD

rin

kN

LE

763

Acy

clo

vir

Psi

ttac

ine

80

PO

T

ID

E

1365

F

or

Pac

hec

o's

vir

us

Acy

clo

vir

Rap

tor

(Per

egri

ne

falc

on

) 80

PO

T

ID

G

Acy

clo

vir

Rap

tor

333

P

O

BID

G

94

Ju

ven

ile d

osa

ge

Alb

en

dazo

le

Avi

an

100

PO

O

nce

E

15

26

Fo

r n

emat

odes

an

d C

apilla

ria

Alb

endaz

ole

A

vian

50

PO

Q

D

E

1526

F

or

nem

ato

des

an

d C

apilla

ria

Alb

endaz

ole

B

ird, A

quat

ic

100

P

O

On

ce

E

1503

F

or

nem

ato

des

an

d C

apilla

ria

Alb

endaz

ole

B

ird, A

quat

ic 5

0 P

O

QD

E

15

03 F

or

nem

ato

des

an

d C

apilla

ria

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 3: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 243

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Alb

endaz

ole

C

ran

e 20

PO

Q

W

E

1361

F

or

trem

ato

des

Alb

endaz

ole

E

mu

10

NL

N

L

G

1471

F

or

fasc

iolia

sis

Alb

endaz

ole

P

engu

in

50

PO

Q

D

E

1478

F

or

nem

ato

des

an

d f

luke

s

Alb

endaz

ole

P

engu

in

100

PO

O

nce

E

14

78

Fo

r n

emat

odes

an

d f

luke

s

Alb

endaz

ole

R

atit

e 0.

264

P

O

BID

E

12

40

Rep

eat

in 2

wee

ks, a

nti

pro

tozo

al

Alf

axalo

ne +

Alf

ad

olo

ne

Avi

an

10-3

6 I

M-I

V-S

C

PR

N

E

704

Alf

axal

on

e +

Alf

ado

lon

e A

vian

5-

10

IV

PR

N

E

1181

Sh

ort

dura

tio

n, m

ay b

e ap

nea

Alf

axal

on

e +

Alf

ado

lon

e A

vian

36

IM-I

P

PR

N

E

1181

Sh

ort

dura

tio

n

Alf

axal

on

e +

Alf

ado

lon

e B

uzz

ard (

Augu

r, L

izza

rd)

10

IV

PR

N

B

1610

Alf

axal

on

e +

Alf

ado

lon

e C

hic

ken

10

IV

PR

N

B

1610

Alf

axal

on

e +

Alf

ado

lon

e C

ran

e 4-

8

IV

PR

N

E

1240

M

ay c

ause

tra

nsi

ent

apn

ea, s

urg

ical

an

esth

esia

fo

r 8

to 1

0 m

in

Alf

axal

on

e +

Alf

ado

lon

e E

agle

(A

fric

an F

ish

, Haw

k, T

awn

y)

and F

alco

ns

10

IV

PR

N

B

1610

Alf

axal

on

e +

Alf

ado

lon

e F

lam

ingo

4-

8

IV

PR

N

E

1240

Alf

axal

on

e +

Alf

ado

lon

e G

osh

awk,

Afr

ican

10

IV

PR

N

B

1610

Alf

axal

on

e +

Alf

ado

lon

eO

wl,

Gre

at-h

orn

ed6-

12IV

PR

NB

1174

Alf

axal

on

e +

Alf

ado

lon

eP

elic

an5.

4IV

PR

NG

595

Alf

axal

on

e +

Alf

ado

lon

eP

igeo

n5-

7IM

-IV

PR

NG

232

Alf

axal

on

e +

Alf

ado

lon

eP

sitt

acin

e5-

10IM

-IV

PR

NE

1240

Alf

axal

on

e +

Alf

ado

lon

eR

apto

r10

IVP

RN

B15

68F

or

wild

inju

red r

apto

rs a

nes

thes

ia in

duct

ion

All

op

uri

no

lA

vian

10-1

5IM

, PO

QD

G58

, 704

Allo

puri

no

lB

udge

riga

r0.

33 g

/L

Dri

nk

NL

G11

1

Allo

puri

no

lB

udge

riga

r0.

67 g

/L

Dri

nk

NL

E76

3F

or

gout

Allo

puri

no

lP

sitt

acin

e10

PO

QD

B10

35F

or

hyp

eruri

cem

ia

Allo

puri

no

lP

sitt

acin

e0.

33 g

/L

Dri

nk

NL

E12

40T

o t

reat

go

ut

Allo

puri

no

lP

sitt

acin

e10

-30

PO

BID

E17

56

Alo

e V

era

Avi

an16

ml/

LD

rin

kQ

DG

1682

Alo

e V

era

Avi

an30

ml/

LD

rin

kQ

DG

111

Am

an

tad

ine H

Cl

Avi

an0.

001

g/L

Dri

nk

NL

E16

50F

or

ort

ho

myx

ovi

ruse

s

Am

anta

din

e H

Cl

Avi

an25

PO

NL

E16

50F

or

ort

ho

myx

ovi

ruse

s

Am

anta

din

e H

Cl

Po

ult

ry2

PO

NL

G43

5

Am

anta

din

e H

Cl

Turk

ey10

PO

QD

G43

5

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 4: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I244

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Am

ikacin

Su

lfate

Am

azo

n, B

lue-

fro

nte

d10

-15

IMB

ID-T

IDA

697

Am

ikac

in S

ulf

ate

Am

azo

n, O

ran

ge-w

inge

d13

-20

IM/IV

BID

A73

6

Am

ikac

in S

ulf

ate

Avi

an10

-15

IM-I

V-S

CB

ID-T

IDA

1473

, 111

Am

ikac

in S

ulf

ate

Bir

d, A

quat

ic18

-20

IMB

IDE

1478

, 155

9

Am

ikac

in S

ulf

ate

Ch

icke

n20

IMT

IDA

1058

Fo

r h

ens

Am

ikac

in S

ulf

ate

Co

ckat

iel

15-2

0IM

BID

-TID

A32

, 697

, 879

Am

ikac

in S

ulf

ate

Co

ckat

oo

, Go

ffin

15-2

0IM

BID

-TID

A69

7

Am

ikac

in S

ulf

ate

Cra

ne

10IM

-SC

BID

E62

9

Am

ikac

in S

ulf

ate

Fo

wl,

Do

mes

tic

10-2

0IM

QD

-TID

A16

31F

or

salm

on

ello

sis

Am

ikac

in S

ulf

ate

Gull

15IM

BID

E13

57

Am

ikac

in S

ulf

ate

Ost

rich

7.6

IMT

IDA

747

Am

ikac

in S

ulf

ate

Par

rot,

Gre

y10

-20

IMB

ID-T

IDA

112,

692

Am

ikac

in S

ulf

ate

Pen

guin

, Afr

ican

15IM

BID

G13

53M

on

ito

r h

ydra

tio

n

Am

ikac

in S

ulf

ate

Pig

eon

15-2

0IM

-IV

BID

G59

0

Am

ikac

in S

ulf

ate

Psi

ttac

ine

15-4

0IM

QD

-BID

E56

5

Am

ikac

in S

ulf

ate

Rap

tor

15-2

0IM

QD

G13

14

Am

ikac

in S

ulf

ate

Rat

ite

7.6-

11IM

BID

G13

08

Am

ikac

in S

ulf

ate

Sto

rk, S

addle

-bill

ed10

IMB

IDG

1645

Am

ino

loid

Rap

tor

0.25

-0.7

5IM

q2w

E11

1In

duce

mo

ltin

g

Am

ino

nit

roth

iazo

leR

apto

r20

-40

PO

NL

E14

63F

or

tric

ho

mo

nia

sis

Am

ino

pen

tam

ide S

ulf

ate

Avi

an0.

05IM

-SC

BID

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1, 1

240.

147

3C

on

tro

l vo

mit

ion

Am

ino

ph

yll

ine

Avi

an

0.5

Neb

uliz

e B

ID-T

ID

G

1199

A

dd a

cety

lcys

tein

e, antibiotic, 5

ml N

aCl

Am

ino

ph

yllin

eA

vian

10IV

-PO

q3h

E11

51

Am

ino

pro

mazin

eA

vian

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IMN

LF

1209

Am

ino

thia

zo

leP

igeo

n5

ml/

LD

rin

kQ

DE

1240

Am

itri

pty

lin

e H

Cl

Psi

ttac

ine

1-5

PO

B-Q

IDD

1446

, 111

, 124

0F

or

beh

avio

ral f

eath

er p

icki

ng

Am

mo

nia

So

luti

on

Avi

an10

ml/

LT

op

ical

PR

NG

111

Add a

loe

vera

+ 4

dro

ps

sulf

on

ate

det

erge

nt,

con

tro

l ski

n p

ruri

tis

Am

ob

arb

ital

So

diu

mA

nse

rifo

rmes

2P

OP

RN

G4

Soak

fo

od in

so

luti

on

Am

ob

arb

ital

So

diu

mD

uck

, Mal

lard

3.6

g/L

fee

dF

eed

On

ceG

1398

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 5: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 245

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Am

oxic

illi

nA

vian

150-

175

PO

QD

-BID

E11

1

Am

oxi

cilli

nA

vian

250

IMQ

DE

704

Lo

ng-

last

ing

pre

par

atio

n

Am

oxi

cilli

nA

vian

0.2-

0.4

g/L

Dri

nk

QD

E70

4So

ft f

eed

Am

oxi

cilli

nA

vian

167

PO

QD

-BID

E74

1

Am

oxi

cilli

nA

vian

150

IM-P

ON

LE

924

Bro

ad s

pec

trum

Am

oxi

cilli

nA

vian

100

PO

BID

E14

31

Am

oxi

cilli

nA

vian

150-

175

PO

QD

-BID

E14

73

Am

oxi

cilli

nA

vian

100-

150

SCQ

DE

1526

Bro

ad s

pec

trum

Am

oxi

cilli

nA

vian

100-

150

IMN

LG

1618

Fo

r o

pen

fra

cture

s

Am

oxi

cilli

nB

ust

ard

100

IM-S

CB

IDE

1240

Am

oxi

cilli

nC

anar

y0.

3 g/

LD

rin

kN

LA

1139

Am

oxi

cilli

nC

anar

y0.

5 g/

kg f

eed

Fee

dO

nce

A11

39

Am

oxi

cilli

nC

hic

ken

16P

OQ

DB

1006

Am

oxi

cilli

nC

urr

awo

ng,

Pie

d25

-50

PO

BID

G16

09P

ost

-surg

ical

Am

oxi

cilli

nD

uck

20D

rin

kQ

DC

705

Am

oxi

cilli

nF

alco

n10

0P

aren

tera

lq2d

G11

28

Am

oxi

cilli

nG

allif

orm

es0.

17 g

/L

Dri

nk

QD

E70

4

Am

oxi

cilli

nG

osh

awk

10P

OB

IDG

127

Pre

cede

wit

h t

icar

cilli

n

Am

oxi

cilli

nG

ull

100

PO

QD

-BID

E13

57

Am

oxi

cilli

nP

engu

in, A

fric

an20

0P

OT

IDG

1353

Am

oxi

cilli

nP

igeo

n20

-90

PO

QD

-BID

A49

3U

se c

apsu

les

Am

oxi

cilli

nP

igeo

n10

0P

OQ

D-B

IDA

565

Gra

m n

egat

ive

bac

teri

a

Am

oxi

cilli

nP

igeo

n50

IMQ

D-B

IDA

565

Gra

m p

osi

tive

bac

teri

a

Am

oxi

cilli

nP

igeo

n18

-91

PO

QD

-BID

A73

3U

se h

igh

do

sage

fo

r E

nte

rob

acte

riac

eae

Am

oxi

cilli

nP

igeo

n1.

5 g/

LD

rin

kN

LA

800

Fo

r Str

epto

cocc

us b

ovis

Am

oxi

cilli

nP

igeo

n15

0IV

-PO

NL

A80

0F

or

Str

epto

cocc

us b

ovis

Am

oxi

cilli

nP

igeo

n0.

2 g/

LD

rin

kN

LA

993

Am

oxi

cilli

nP

igeo

n75

-100

PO

BID

A10

66

Am

oxi

cilli

nP

igeo

n20

Dri

nk

QD

C70

4

Am

oxi

cilli

nP

igeo

n25

-50

PO

QD

G47

Am

oxi

cilli

nP

oult

ry15

-20

Dri

nk

QD

C70

5

Am

oxi

cilli

nP

oult

ry55

-110

PO

BID

-TID

G58

5

Am

oxi

cilli

nP

sitt

acin

e15

0-17

5P

OQ

D-B

IDE

565

Am

oxi

cilli

nP

sitt

acin

e25

0IM

QD

E11

40

Am

oxi

cilli

nP

sitt

acin

e10

0SC

NL

G16

13

Am

oxi

cilli

nR

apto

r15

0IM

-PO

BID

E14

00B

acte

rial

infe

ctio

ns

Am

oxi

cilli

nR

apto

r50

IMB

IDE

1612

Am

oxi

cilli

nR

atit

e15

-22

PO

BID

G13

08

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 6: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I246

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Am

oxic

illi

n +

Tylo

sin

Avi

an10

g/L

Dri

nk

QD

E14

92F

or

flo

ck t

reat

men

t o

f b

acte

rial

an

d

myc

op

lasm

al in

fect

ion

s

Am

oxi

cilli

n +

Tyl

osi

nA

vian

3000

PO

QD

E14

92

Am

oxi

cilli

n +

Tyl

osi

nA

vian

10 g

/L

Dri

nk

QD

E16

50

Am

oxi

cilli

n +

Tyl

osi

nA

vian

3000

PO

QD

E16

50

Am

oxic

illi

n D

ep

ot

Bust

ard

100-

250

IM-S

Cq3-

7dA

1127

, 124

0

Am

oxi

cilli

n D

epo

tP

igeo

n15

0IM

q2d

A49

3L

on

g-la

stin

g fo

rmula

tio

n

Am

oxi

cilli

n D

epo

tP

igeo

n15

0-20

0SC

QD

A99

1L

on

g-la

stin

g o

il b

ased

susp

.

Am

oxic

illi

n S

od

ium

+

Cla

vu

lan

ate

Po

tass

ium

Am

azo

n P

arro

t12

5N

LT

IDA

1491

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Avi

an12

5P

OQ

IDE

704

Do

sage

bas

ed o

n a

mo

xici

llin

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Avi

an10

0P

O, I

MB

IDE

1431

Use

ful i

n y

oun

g b

irds

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Avi

an50

IMB

ID-Q

IDE

1470

Fo

r b

acte

rial

infe

ctio

n w

ith

live

r dis

ease

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Avi

an15

0-17

5IM

-PO

BID

E14

74F

or

neo

nat

al s

epti

cem

ia

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Bir

d, A

quat

ic12

5-15

0IM

, PO

BID

E14

78P

re-

and p

ost

-op

erat

ive

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Can

ary

125

Gav

age

BID

G11

39F

or

GI

infe

ctio

n

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Ch

icke

n0.

5 g/

LD

rin

kN

LA

801

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Haw

k, R

ed-t

aile

d50

PO

BID

G16

26P

ost

-op

erat

ive

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Ow

l, G

reat

-ho

rned

125

PO

BID

G17

3

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Pas

seri

ne

200

NL

TID

G14

89F

or

fro

stb

ite

asso

ciat

ed s

kin

infe

ctio

n

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Pig

eon

125

Gav

age

BID

B75

1F

or

loca

lized

gut

infe

ctio

n

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Psi

ttac

ine

100

PO

BID

D14

46F

or

stap

hyl

oco

ccal

der

mat

itis

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Rap

tor

150

PO

, IM

BID

E14

00, 1

433

Can

be

nep

hro

toxi

c

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Rap

tor

125

PO

BID

G23

4

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 7: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 247

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Am

oxi

cilli

n S

odiu

m +

Cla

vula

nat

e P

ota

ssiu

m

Rat

ite

11-1

5IV

-PO

TID

G13

08

Am

ph

ote

ricin

BA

maz

on

, Yel

low

-nap

ed50

-75

mg

TD

ITQ

DG

740

Am

ph

ote

rici

n B

Avi

an1

ITT

IDE

625

Add f

lucy

tosi

ne

+ I

V a

mp

ho

teri

cin

B,

asp

ergi

llosi

s th

erap

y

Am

ph

ote

rici

n B

A

vian

1.

5 IV

T

ID

E

625,

674

S

ee a

bo

ve

Am

ph

ote

rici

n B

Avi

an10

0P

OB

IDE

1492

Fo

r m

acro

rhab

do

sis

(fo

rmer

ly m

egab

acte

ria

or

avia

n g

astr

ic y

east

)

Am

ph

ote

rici

n B

Avi

an0.

83gL

Neb

uliz

eB

IDE

1526

Fo

r as

per

gillo

sis

ther

apy.

Must

use

ste

rile

wat

er -

NaC

l in

acti

vate

s A

mp

ho

teri

cin

Am

ph

ote

rici

n B

Avi

an1

IPQ

DG

861

Am

ph

ote

rici

n B

Bir

d, A

quat

ic10

0-20

0P

OT

ID-Q

IDE

1503

Fo

r G

I ca

ndid

iasi

s

Am

ph

ote

rici

n B

Bir

d, A

quat

ic1.

5IV

-SC

QD

E15

03F

or

asp

ergi

llosi

s th

erap

y

Am

ph

ote

rici

n B

Budge

riga

r10

9P

OB

IDB

589

Fo

r m

acro

rhab

do

sis

(fo

rmer

ly m

egab

acte

ria

or

avia

n g

astr

ic y

east

)

Am

ph

ote

rici

n B

Cra

ne

0.33

-0.6

7 g/

LN

ebuliz

eT

IDG

1361

Am

ph

ote

rici

n B

Gull

1IT

BID

E13

57

Am

ph

ote

rici

n B

Gull

1.5

IVT

IDE

1357

Am

ph

ote

rici

n B

Psi

ttac

ine

1.5

IVB

ID-T

IDE

111,

745

Am

ph

ote

rici

n B

Psi

ttac

ine

1IT

BID

-TID

E11

1, 7

41, 1

309

Am

ph

ote

rici

n B

Rap

tor

1.5

IVT

IDB

1178

Add I

T a

mp

ho

teri

cin

B +

flu

cyto

sin

e +

rifa

mp

in f

or

asp

ergi

llosi

s

Am

pic

illi

nA

maz

on

Par

rot

150-

200

PO

BID

-TID

A56

7M

ay g

ive

com

bin

atio

n o

f b

oth

ora

l an

d

par

ente

ral

Am

pic

illin

An

seri

form

es10

0IM

q4h

E13

18, 1

358

Am

pic

illin

Avi

an0.

25g/

kgF

eed

QD

E74

1

Am

pic

illin

Avi

an1.

041

g/L

Dri

nk

QD

E74

1

Am

pic

illin

Can

ary

1-2

g/L

Dri

nk

QD

G49

Am

pic

illin

Can

ary

2-3

g/kg

fo

od

Fee

dQ

DG

49In

so

ft f

oo

d

Am

pic

illin

Cra

ne

15-2

0IM

-SC

BID

A59

6

Am

pic

illin

Cra

ne,

Gre

ater

San

d H

ill20

IMB

IDA

847

Am

pic

illin

Em

u20

IMB

IDA

847

Am

pic

illin

Fal

con

100

IM-P

OB

IDE

1027

Am

pic

illin

P

arro

t, B

lue-

nap

ed

150-

200

PO

BID

-TID

A56

7M

ay g

ive

com

bin

atio

n o

f b

oth

ora

l an

d

par

ente

ral

Am

pic

illin

Pig

eon

25-1

20P

OQ

D-B

IDA

493

Use

cap

sule

s

Am

pic

illin

Pig

eon

100

IMq2d

A49

3L

on

g-la

stin

g fo

rmula

tio

n

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 8: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I248

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Am

pic

illin

Po

ult

ry55

-110

Par

ente

ral

BID

-TID

G58

5

Am

pic

illin

Psi

ttac

ine

100

IMq4h

E11

1

Am

pic

illin

Psi

ttac

ine

100-

200

PO

QID

E12

40P

oo

rly

abso

rbed

Am

pic

illin

Rap

tor

100-

250

IMN

LE

1463

Am

pic

illi

n S

od

ium

Am

azo

n P

arro

t50

-100

IMq4-

8hA

567

May

giv

e co

mb

inat

ion

of

bo

th o

ral a

nd

par

ente

ral

Am

pic

illin

So

diu

mP

igeo

n15

0IM

QD

-BID

A49

3

Am

pic

illin

So

diu

mP

igeo

n77

3IM

QD

-BID

A73

3F

or

Ent

erob

acte

riac

eae

Am

pic

illin

So

diu

mP

igeo

n15

5IM

QD

-BID

A73

3

Am

pic

illin

So

diu

mR

atit

e0.

1 -

0.2

g/L

Dri

nk

NL

G41

8C

lost

ridia

l tre

atm

ent

Am

pro

liu

mA

vian

0.04

8-0.

096g

/L

Dri

nk

QD

E11

1

Am

pro

lium

A

vian

0.

08 g

/L

D

rin

k Q

D

E

1492

C

occ

idio

stat

ic, o

verd

ose

rev

erse

d b

y

adm

inis

trat

ion

of

vita

min

B c

om

ple

x

Am

pro

lium

Ch

icke

n40

-250

mg/

kg f

oo

dF

eed

QD

E56

4N

o s

laugh

ter

wit

hdra

wal

Am

pro

lium

Cra

ne

0.06

g/L

Dri

nk

QD

E13

61F

or

cocc

idio

sis

Am

pro

lium

Pig

eon

0.2

g/L

Dri

nk

QD

G23

2

Am

pro

lium

Po

ult

ry1.

25 c

c/L

Dri

nk

QD

G58

5U

se 2

0% p

ow

der

fo

rmula

tio

n

Am

pro

lium

Psi

ttac

ine

0.25

g/L

Dri

nk

QD

E13

65F

or

sarc

ocy

sto

sis

Ap

ram

ycin

Ch

icke

n0.

5 g/

LD

rin

kQ

DB

881

Fo

r co

libac

illo

sis

Are

co

lin

e H

yd

rob

rom

ide

Pel

ican

, Bro

wn

1-1.

6P

OQ

HB

1089

Giv

e th

iab

endaz

ole

pre

vio

us

day

Ars

an

ilic

Acid

Po

ult

ry0.

1 g/

kg f

oo

dF

eed

QD

E56

4N

utr

itio

nal

use

, 5-d

ay s

laugh

ter

wit

hdra

wal

Asc

orb

ic A

cid

A

vian

20

-40

IM

QD

-QW

E

14

73

Asc

orb

ic A

cid

Avi

an20

-50

IM-P

ON

LE

924

Fo

r vi

ral i

nfe

ctio

n, l

iver

dis

ease

, str

ess

Asc

orb

ic A

cid

Avi

an20

-40

IMQ

D-Q

WE

1473

Asc

orb

ic A

cid

Ost

rich

20-5

0 m

g T

DIM

q2d

G40

1F

or

chic

ks

Asc

orb

ic A

cid

Rap

tor

250

PO

QD

E13

59A

nti

oxi

dan

t th

erap

y, a

dm

inis

ter

duri

ng

lead

chel

atio

n t

her

apy

Asp

ara

gin

ase

Avi

an0.

4 K

IU/kg

IMQ

WE

1470

Asp

arag

inas

eO

wl,

Gre

at-h

orn

ed1.

7 K

IU/kg

SCO

nce

F12

5

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 9: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 249

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Asp

irin

Am

azo

n, R

ed L

ore

d0.

5-1

PO

QD

-BID

G17

56A

dd f

atty

aci

d o

meg

a 6:

om

ega

3 <

6:1

rat

io,

use

un

til r

enal

his

tolo

gy n

orm

aliz

es f

or

ren

al

dis

ease

Asp

irin

Am

azo

n, Y

ello

w-n

aped

0.5-

1P

OB

IDG

1033

Asp

irin

Avi

an5

PO

TID

-QID

D15

33

Asp

irin

Avi

an1.

2 g/

LD

rin

kQ

DE

1650

Asp

irin

Avi

an5

PO

TID

G13

41, 1

671

Asp

irin

Psi

ttac

ine

0.5-

1P

OQ

D-B

IDE

1756

Asp

irin

Sto

rk, S

addle

-bill

ed1

PO

QD

G16

45

Ast

rag

alu

s A

vian

1

0 dro

ps/

kg P

O

TID

E

12

05

Ch

ron

ic G

I p

rob

lem

s an

d in

fect

ion

s

Ast

raga

lus

Avi

an33

-66

dro

ps/

kgP

OQ

DE

1435

Imm

un

e st

imula

nt

Ati

pam

ezo

le

Ati

pam

ezo

leA

nse

rifo

rmes

0.25

IVP

RN

D15

03A

dd f

lum

azen

il to

rev

erse

ket

amin

e +

med

eto

mid

ine

+ m

idaz

ola

m

Ati

pam

ezo

leA

vian

0.25

-0.3

8IM

PR

NE

1181

Rev

erse

ket

amin

e +

xyl

azin

e o

r ke

tam

ine

+

med

eto

mid

ine

Ati

pam

ezo

leD

uck

, Mal

lard

0.25

mg

TD

IVP

RN

B76

4A

dd f

lum

azen

il

Ati

pam

ezo

leP

igeo

n0.

5IM

PR

NB

1588

Rev

erse

med

eto

mid

ine

Ati

pam

ezo

leP

sitt

acin

e0.

25-0

.38

IMP

RN

E12

40R

ever

se x

ylaz

ine

or

med

eto

mid

ine

Atr

op

ine

An

seri

form

es0.

1IM

-IV

q3-

4hD

1150

Fo

r an

tich

olin

este

rase

po

iso

nin

g

Atr

op

ine

Avi

an0.

04-0

.1IM

-SC

On

ceG

1309

Pre

anes

thet

ic

Atr

op

ine

Avi

an0.

1-0.

2IM

-SC

q4h

E11

51F

or

cho

liner

gic

toxi

n

Atr

op

ine

Avi

an0.

2-0.

5IV

q3-

4hE

1554

Fo

r an

tich

olin

este

rase

to

xici

ty

Atr

op

ine

Avi

an0.

01-0

.02

Par

ente

ral

q3-

4hE

1650

Fo

r o

rgan

op

ho

sph

ate

toxi

city

Atr

op

ine

Avi

an0.

1-0.

2IM

-SC

PR

NG

1309

Fo

r o

rgan

op

ho

sph

ate

po

iso

nin

g

Atr

op

ine

Can

ary

0.2

Par

ente

ral

q4h

G17

14F

or

con

vuls

ion

s p

oss

ibly

cau

sed b

y

org

ano

ph

osp

hat

e to

xici

ty

Atr

op

ine

Pig

eon

0.27

IM-I

Vq4-

8hG

590

Atr

op

ine

Psi

ttac

ine

0.05

IM-S

CQ

HE

1240

Fo

r ac

etyl

cho

lines

tera

se p

ois

on

ing

Atr

op

ine

Psi

ttac

ine

0.5

IM-S

CN

LE

1688

Atr

op

ine

Rap

tor

0.5

IM-I

VP

RN

G61

[May

th

icke

n s

ecre

tio

ns

and in

crea

se r

isk

of

airw

ay o

bst

ruct

ion

- K

LM

]

Atr

op

ine

Rap

tor

0.1

IM-I

Vq3-

4hE

1240

, 140

0F

or

acet

ylch

olin

este

rase

po

iso

nin

g

Atr

op

ine

Rap

tor

0.02

-0.0

5IM

-IV

PR

NE

1359

Fo

r o

rgan

op

ho

sph

ate

toxi

city

Azam

eth

iph

os

Po

ult

ry5-

20 g

/L

To

pic

alN

LE

1479

Ap

ply

to

an

imal

fac

iliti

es, i

nse

ct s

pra

y

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 10: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I250

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Azap

ero

ne

Ost

rich

4-6

IMP

RN

B52

2A

dd m

eto

mid

ate,

ch

ick

do

sage

Aza

per

on

eO

stri

ch3.

3-6.

6IM

PR

NG

283

Add m

eto

mid

ate

Aza

per

on

eR

atit

e0.

5-2

IMO

nce

G12

26A

dd k

etam

ine

+ d

iaze

pam

aft

er 1

0 to

15

min

ute

s, s

edat

ion

Azit

hro

mycin

Avi

an50

-80

PO

QD

G70

2F

or

chla

myd

op

hilo

sis

Azi

thro

myc

inA

vian

43P

OQ

DG

1154

Add e

tham

buto

l + r

ifab

uti

n f

or

myc

ob

acte

rio

sis

Azi

thro

myc

inF

alco

n40

PO

QW

F11

57F

or

chla

myd

op

hilo

sis

Bach

flo

wer

Avi

an1

dro

pD

rin

kQ

IDG

912

Fo

r ca

lmin

g ef

fect

, als

o a

pp

ly t

op

ical

ly a

s

spra

y

Bac

h f

low

er

Avi

an

45-7

5 dro

ps/

L

PO

Q

ID

G

912

S

ee a

bo

ve

Bacit

racin

Po

ult

ry11

0-22

0 m

g/kg

fee

dF

eed

QD

E56

4N

utr

itio

nal

use

, no

sla

ugh

ter

wit

hdra

wal

Bac

itra

cin

Rat

ite

0.4

g/L

Dri

nk

NL

G41

8C

lost

ridia

l th

erap

y

Bam

berm

ycin

Ch

icke

n3.

3 m

g/kg

fee

dF

eed

On

ceB

400

Bam

ber

myc

inO

stri

ch0.

07 m

g/kg

fee

dF

eed

On

ceC

283

Gro

wth

pro

mo

tan

t

Bari

um

Su

lfate

Avi

an50

ml/

kgP

ON

LE

1151

G.I

. pro

tect

ant

and a

nti

infl

amm

ato

ry

Bar

ium

Sulf

ate

Avi

an10

-20

ml/

kgP

ON

LE

1482

Mix

50:

50 w

ith

han

d-f

eedin

g fo

rmula

fo

r G

I

con

tras

t ra

ds

Ben

zyl

Ben

zo

ate

Pig

eon

25%

so

luti

on

To

pic

alP

RN

E70

4A

pp

ly t

o le

sio

n

Ben

zyl B

enzo

ate

Rap

tor

10%

so

luti

on

To

pic

alQ

DE

1612

Fo

r K

nem

idoc

opte

s

Beta

meth

aso

ne

Avi

an0.

1IM

NL

D, E

,

G

201,

153

3, 1

573

Bet

amet

has

on

eB

ird, A

quat

ic0.

1IM

NL

E15

03

Bet

amet

has

on

eP

igeo

n1

IMO

nce

E70

4A

nap

hyl

axis

Bio

tin

Rap

tor

0.02

5P

OQ

DE

1068

Duri

ng

regr

ow

th o

f cl

aw

Bio

tin

Rap

tor

0.05

PO

QD

E12

40A

id in

bea

k an

d c

law

gro

wth

Bis

mu

th S

ub

sali

cyla

teA

vian

35P

OB

IDE

1240

May

hel

p r

emo

ve in

gest

ed t

oxi

ns

Bis

muth

Sub

salic

ylat

eA

vian

35-8

8P

OO

nce

E15

26E

nte

ric

coat

ing

for

oile

d b

irds

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 11: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 251

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Bre

wers

yeast

An

seri

form

es75

g/kg

fee

dF

eed

QD

E13

58F

or

nia

cin

def

icie

ncy

wit

h le

g def

orm

itie

s,

wea

knes

s, p

oo

r gr

ow

th

Bro

mh

exin

e H

Cl

Avi

an3-

6IM

NL

E70

4, 1

434

Bro

mh

exin

e H

Cl

Avi

an1.

5IM

QD

-BID

E15

26, 1

617

Liq

uef

y re

spir

ato

ry m

ucu

s

Bro

mh

exin

e H

Cl

Rap

tor

1.5

IMQ

DE

1612

Muco

lyti

c

Bu

nam

idin

e H

Cl

Rap

tor

25P

ON

LE

1463

An

thel

min

tic

Bu

piv

acain

e H

Cl

Par

rot,

Gre

y2

IMP

RN

A13

39M

ain

tain

pla

sma

con

cen

trat

ion

fo

r le

ss t

han

2

ho

urs

Bu

pre

no

rph

ine H

Cl

Avi

an0.

01-0

.05

IM-I

V-S

CB

IDE

1167

Bup

ren

orp

hin

e H

Cl

Pig

eon

0.5

IMq5h

B16

56

Bu

torp

han

ol

Tart

rate

Am

azo

n, H

isp

anio

lan

1-3

IMN

LA

1339

Buto

rph

ano

l Tar

trat

eC

ock

ato

o1

NL

PR

NB

1678

Iso

flura

ne

spar

ing

Buto

rph

ano

l Tar

trat

eP

arro

t, G

rey

1-2

IMN

LA

1339

Pla

sma

leve

ls m

ain

tain

ed le

ss t

han

2 h

ours

at

2 m

g/kg

Buto

rph

ano

l Tar

trat

eP

arro

t, G

rey

1IM

NL

B58

6, 1

339

Buto

rph

ano

l Tar

trat

eP

igeo

n4

IMq3h

B16

56

Buto

rph

ano

l Tar

trat

eP

sitt

acin

e3-

4IV

-PO

NL

E11

1, 1

249

Buto

rph

ano

l Tar

trat

eP

sitt

acin

e3-

4IV

-PO

TID

E12

40A

lso

an

alge

sic

Buto

rph

ano

l Tar

trat

eR

apto

r2-

4IM

-SC

QD

E13

59

Buto

rph

ano

l Tar

trat

eR

hea

0.7

IMP

RN

G16

28A

dd k

etam

ine

+ m

edet

om

idin

e

Buto

rph

ano

l Tar

trat

eT

ouca

n, T

oco

2IM

On

ceG

1379

Po

st-s

urg

ical

pai

n

Calc

itri

ol

Avi

an0.

0000

25 (

0.02

5ug/

kg)

Gav

age

QD

G11

83A

dd c

alci

um

so

urc

e to

gav

age

for

hyp

oca

lcae

mia

Calc

ium

Bo

rog

luco

nate

Avi

an20

0IM

-IV

QD

E14

31U

sed d

uri

ng

egg

layi

ng

pro

ble

ms,

oft

en w

ith

oxy

toci

n

Cal

cium

Bo

rogl

uco

nat

eA

vian

100-

500

IM-S

CN

LE

1434

Fo

r eg

g b

indin

g an

d h

ypo

calc

emic

tet

any

Cal

cium

Bo

rogl

uco

nat

eG

osh

awk

300

IVN

LG

234

Cal

cium

Bo

rogl

uco

nat

eP

igeo

n10

0-50

0IM

-SC

NL

E14

32F

or

egg

bin

din

g an

d h

ypo

calc

emic

tet

any

Cal

cium

Bo

rogl

uco

nat

eP

sitt

acin

e10

0-20

0IM

-IV

NL

E12

40

Cal

cium

Bo

rogl

uco

nat

eR

apto

r10

0-50

0IV

-SC

On

ceE

1240

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 12: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I252

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Cal

cium

Bo

rogl

uco

nat

eR

apto

r10

-50

IV-S

CO

nce

E14

00F

or

egg

bin

din

g o

r h

ypo

calc

aem

ia, g

ive

IV

slo

wly

Calc

ium

Carb

on

ate

Rap

tor

10 g

/kg

fo

od

Fee

dO

nce

D16

12F

or

ost

eodys

tro

ph

y

Calc

ium

Glu

bio

nate

Avi

an0.

44 g

/L

Dri

nk

NL

E14

92F

or

egg

bin

din

g an

d c

alci

um

def

icie

nci

es

Cal

cium

Glu

bio

nat

eA

vian

150

PO

BID

G54

Calc

ium

Glu

bio

nate

+

Calc

ium

Lacto

bio

nate

Avi

an36

3P

OQ

DE

1617

Calc

ium

Glu

co

nate

Avi

an10

0-30

0IM

-SC

NL

E14

80A

dd p

hyt

on

adio

ne

for

ble

edin

g sy

ndro

me

Cal

cium

Glu

con

ate

Avi

an5-

10IM

-SC

BID

E14

73

Cal

cium

Glu

con

ate

Avi

an50

-100

IVN

LE

1473

Slo

wly

to

eff

ect

Cal

cium

Glu

con

ate

Avi

an5-

10IM

NL

E14

74

Cal

cium

Glu

con

ate

Avi

an50

-100

IVN

LE

1474

Giv

e sl

ow

ly, f

ollo

w w

ith

oxy

toci

n o

r

din

op

rost

on

e fo

r eg

g b

indin

g, m

ay a

dd

vita

min

E +

sel

eniu

m

Cal

cium

Glu

con

ate

Avi

an10

0-30

0SC

NL

E14

81

Calc

ium

Gly

cero

ph

osp

hate

+

Calc

ium

Lacta

te

Avi

an5-

10IM

-SC

NL

E15

70F

or

egg

bin

din

g

Cal

cium

Gly

cero

ph

osp

hat

e

+ C

alci

um

Lac

tate

Avi

an0.

5-1

IMQ

WG

54

Cal

cium

Gly

cero

ph

osp

hat

e

+ C

alci

um

Lac

tate

Lo

ry, R

ed7

IMN

LG

1621

Add o

xyto

cin

fo

r eg

g b

indin

g

Cal

cium

Gly

cero

ph

osp

hat

e

+ C

alci

um

Lac

tate

Par

rot,

Gre

y5-

10IM

-SC

BID

G88

Acu

te t

her

apy

Cam

ben

dazo

leA

vian

60-1

00P

OQ

DG

57A

void

duri

ng

bre

edin

g se

aso

n

Cam

ben

daz

ole

Pig

eon

75P

OQ

DE

1051

Fo

r as

cari

ds

and c

apill

aria

Cap

ryli

c A

cid

Avi

an27

0P

ON

LE

111

Adju

nct

to

asp

ergi

llosi

s th

erap

y

Carb

ary

lA

vian

N/A

To

pic

alN

LE

111

5% m

ixtu

re, p

ow

der

fo

rmula

tio

n

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 13: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 253

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Car

bar

ylA

vian

N/A

To

pic

alN

LE

1240

5% m

ixtu

re, l

igh

tly

dust

fea

ther

s fo

r

ecto

par

asit

es

Carb

en

icil

lin

Dis

od

ium

Avi

an15

0IM

-PO

NL

E92

4G

ram

neg

ativ

e, P

seud

omon

as

Car

ben

icill

in D

iso

diu

mA

vian

100

IMT

IDG

55

Car

ben

icill

in D

iso

diu

mA

vian

100-

200

IMB

IDG

861

Fre

eze

smal

l po

rtio

ns

indef

init

ely

Car

ben

icill

in D

iso

diu

mC

ran

e10

0IM

-IV

BID

-TID

E62

9, 1

361

Car

ben

icill

in D

iso

diu

mO

wl,

Gre

at-h

orn

ed15

0P

OB

IDG

173

Car

ben

icill

in D

iso

diu

mP

igeo

n10

0IM

BID

-TID

G26

0

Car

ben

icill

in D

iso

diu

mP

sitt

acin

e10

0-20

0IM

TID

-QID

E56

5

Car

ben

icill

in D

iso

diu

mP

sitt

acin

e10

0IM

BID

E76

3

Car

ben

icill

in D

iso

diu

mR

apto

r10

0-20

0IM

TID

E12

40

Car

ben

icill

in D

iso

diu

mR

apto

r10

0IT

QD

E12

40F

or

Gra

m n

egat

ive

bac

teri

a, s

yner

gist

ic

w/am

ino

glyc

osi

des

Car

ben

icill

in D

iso

diu

mR

apto

r10

0-20

0IM

TID

E14

00

Carb

on

Dio

xid

e G

as

Avi

anN

/A

IHN

LE

1564

Euth

anas

ia

Carb

op

lati

n

Am

azo

n, Y

ello

w-n

aped

125

mg/

m3

I

V

q2-

3w

G

1033

D

ilute

wit

h 5

% d

extr

ose

Car

bo

pla

tin

B

udge

riga

r 5

IV

QM

G

12

59

Dilu

te 1

:10

wit

h s

teri

le w

ater

Carb

oxym

eth

ylc

ell

ulo

se

So

diu

m

Avi

an0.

1% s

olu

tio

nD

rin

kQ

DG

1457

Add a

mp

ho

teri

cin

B, m

ix f

resh

dai

ly, a

llow

to

stan

d o

vern

igh

t, d

isso

lve

dru

g in

th

e A

M

Carf

en

tan

il C

itra

teO

stri

ch3

mg

TD

IMP

RN

B52

1A

dd x

ylaz

ine

Car

fen

tan

il C

itra

teO

stri

ch0.

024

NL

PR

NG

465

Carn

idazo

leA

vian

33P

OO

nce

E15

26F

or

tric

ho

mo

nia

sis,

no

fo

od/w

ater

nig

ht

bef

ore

tre

atm

ent

plu

s n

o w

ater

2 t

o 3

ho

urs

afte

r tr

eatm

ent

Car

nid

azo

leA

vian

20-3

0P

OO

nce

E15

54F

or

tric

ho

mo

nia

sis

and g

iard

iasi

s

Car

nid

azo

leB

ird, A

quat

ic33

PO

On

ceE

1503

Car

nid

azo

leB

ust

ard

20-2

5P

OO

nce

E12

40

Car

nid

azo

leD

ove

30P

ON

LG

61

Car

nid

azo

leF

alco

n25

PO

On

ceB

1420

Fo

r T

tich

om

on

iasi

s, le

ss e

ffec

tive

th

an

mult

iday

dim

etri

daz

ole

Car

nid

azo

leF

inch

20-3

0P

OO

nce

E15

72

Car

nid

azo

leP

igeo

n20

-30

PO

On

ceD

1221

Fo

r tr

ich

om

on

iasi

s

Car

nid

azo

leP

igeo

n20

0P

OO

nce

E11

1, 1

473

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 14: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I254

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Car

nid

azo

leP

igeo

n12

.5-2

5P

OO

nce

E12

40U

se lo

wer

do

sage

fo

r ju

ven

iles

Car

nid

azo

leP

igeo

n20

-30

PO

QW

-q2w

E13

64

Car

nid

azo

leP

sitt

acin

e20

-30

PO

On

ceE

1240

Fo

r tr

ich

om

on

iasi

s, h

exam

itia

sis,

his

tom

on

iasi

s, u

se lo

wer

do

sage

fo

r ju

ven

iles

Car

nid

azo

leR

apto

r30

PO

QD

G61

Carp

rofe

nA

maz

on

, Ora

nge

-win

ged

4IM

BID

G13

77P

ost

-surg

ical

Car

pro

fen

An

seri

form

es4

SCQ

DE

1190

Car

pro

fen

An

seri

form

es5-

10IM

NL

G13

45

Car

pro

fen

Avi

an1-

2IM

-PO

BID

D15

33

Car

pro

fen

Avi

an4

IM-I

V-P

ON

LE

1167

Car

pro

fen

Avi

an5-

10IM

QD

E14

31P

re-o

per

ativ

e p

ain

kille

r

Car

pro

fen

Bir

d, A

quat

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BID

E15

03

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pro

fen

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eon

5-10

IMN

LG

1345

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pro

fen

Psi

ttac

ine

2-10

IM-I

V-S

CQ

DE

1240

Po

st-s

urg

ical

pai

n

Car

pro

fen

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tor

1-2

IM-I

V-P

OB

IDD

1400

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pro

fen

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tor

2-10

IM-I

V-S

CQ

DE

1240

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st-s

urg

ical

pai

n

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dro

xil

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eon

100

PO

BID

G26

0

Cefa

zo

lin

So

diu

mC

ran

e25

-30

IM-I

VT

IDE

629

Cef

azo

lin S

odiu

mP

oult

ry11

-55

NL

BID

-TID

G58

5

Cef

azo

lin S

odiu

mR

apto

r10

0IM

On

ceE

1359

Per

iop

erat

ive,

use

am

oxi

cilli

n/cl

avula

nat

e

po

st-o

per

ativ

e

Cefo

taxim

e S

od

ium

Am

azo

n P

arro

t75

-100

IMq4-

8hA

697

Cef

ota

xim

e So

diu

mA

maz

on

, Blu

e-fr

on

ted

100

IMT

IDA

748

Cef

ota

xim

e So

diu

mA

vian

75-1

00IM

-IV

TID

-QID

A14

73

Cef

ota

xim

e So

diu

mB

ird, A

quat

ic10

0IM

TID

-QID

E14

78F

or

ho

ck jo

int

pre

ssure

so

re in

fect

ion

s

Cef

ota

xim

e So

diu

mC

ran

e50

-100

IM-S

CT

IDE

629

Cef

ota

xim

e So

diu

mH

awk,

Red

-tai

led

100

IMN

LG

1626

Intr

a-o

per

ativ

e

Cef

ota

xim

e So

diu

mP

igeo

n10

0IM

BID

-TID

G26

0

Cef

ota

xim

e So

diu

mP

sitt

acin

e50

-100

IMT

IDE

565

Cef

ota

xim

e So

diu

mP

sitt

acin

e50

-100

SCT

IDE

632

Neo

nat

e do

sage

Cef

ota

xim

e So

diu

mP

sitt

acin

e10

0IM

BID

E76

3F

roze

n r

eco

nst

itute

d d

rugs

last

s 12

wee

ks in

free

zer,

10

day

s in

ref

rige

rato

r

Cef

ota

xim

e So

diu

mR

apto

r10

0IM

-IV

On

ceE

1359

Per

iop

erat

ive,

use

am

oxi

cilli

n/cl

avula

nat

e

po

st-o

per

ativ

e

Cef

ota

xim

e So

diu

mR

atit

e25

IMT

IDG

1308

Fo

r yo

un

g b

irds

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 15: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 255

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Ceft

azid

ime

Psi

ttac

ine

75-2

00IM

-IV

BID

-QID

E17

56F

or

bac

teri

al n

eph

riti

s

Ceft

iofu

r S

od

ium

Am

azo

n, O

ran

ge-w

inge

d10

IMB

ID-T

IDA

788

Cef

tio

fur

Sodiu

mA

vian

50-1

00IM

QID

E12

40

Cef

tio

fur

Sodiu

mC

hic

ken

0.16

mg

TD

IMQ

DA

788

Cef

tio

fur

Sodiu

mC

ock

atie

l10

IMq4h

A78

8

Cef

tio

fur

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mP

sitt

acin

e10

0IM

TID

E17

56F

or

bac

teri

al n

eph

riti

s

Cef

tio

fur

Sodiu

mR

atit

e10

-20

IMB

IDG

1308

Ceft

riaxo

ne S

od

ium

Am

azo

n P

arro

t75

-100

IMq4-

8hA

697

Cef

tria

xon

e So

diu

mA

vian

75-1

00IM

-IV

TID

-QID

E11

1

Cele

co

xib

Avi

an (

Mac

aw)

10P

OQ

DG

1750

Fo

r p

rove

ntr

icula

r dila

tati

on

dis

ease

sym

pto

ms

Cep

hale

xin

Avi

an35

-50

PO

q4-

6hE

111

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hal

exin

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an40

-100

IM-P

OT

ID-Q

IDE

1240

Fo

r E

. col

i an

d P

rote

us

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hal

exin

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an35

-50

PO

q4-

6hE

1473

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hal

exin

Avi

an35

-50

PO

QID

E14

92

Cep

hal

exin

Bir

d, A

quat

ic35

-50

PO

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E15

03

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exin

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ard

40-1

00IM

-PO

TID

-QID

E12

40F

or

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oli

and P

rote

us

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hal

exin

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ne

35-5

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IDA

596

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hal

exin

Cra

ne

100

IMQ

IDA

697

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hal

exin

Cra

ne

100

PO

q4-

6hE

111

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hal

exin

Cra

ne

35-5

0P

OQ

IDA

457,

847

Cep

hal

exin

Duck

35-5

0P

Oq2-

3hA

457

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hal

exin

Duck

100

IMB

ID-T

IDA

697

Cep

hal

exin

Duck

35-5

0P

OQ

IDA

847

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hal

exin

Em

u35

-50

PO

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A41

8, 4

57, 8

47

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Em

u10

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7

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exin

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eon

35-5

0P

OQ

IDA

847

Cep

hal

exin

Pig

eon

100

PO

BID

-TID

G26

0

Cep

hal

exin

Po

ult

ry55

-110

NL

BID

G58

5

Cep

hal

exin

Psi

ttac

ine

35-5

0P

OQ

IDE

763

Cep

hal

exin

Psi

ttac

ine

100

PO

TID

G69

7

Cep

hal

exin

Quai

l10

0IM

BID

-TID

A69

7

Cep

hal

exin

Quai

l, B

ob

wh

ite

35-5

0P

Oq2-

3hA

457

Cep

hal

exin

Quai

l, Ja

pan

ese

35-5

0P

OQ

IDA

847

Cep

hal

exin

Rap

tor

40-1

00IM

-PO

TID

-QID

E12

40

Cep

hal

exin

Rap

tor

50-1

00IM

-PO

TID

E14

00

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 16: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I256

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Cep

hal

exin

Rap

tor

50P

OQ

IDG

234

Cep

hal

exin

Rat

ite

15-2

2P

OT

IDG

1308

Cep

halo

thin

So

diu

mA

vian

100

IM-I

VQ

IDA

1473

Cep

hal

oth

in S

odiu

mA

vian

100

IM-I

VQ

IDE

111

Cep

hal

oth

in S

odiu

mA

vian

100

IMq2-

6hE

565

Cep

hal

oth

in S

odiu

mA

vian

100

IMQ

IDE

741

No

gas

tro

inte

stin

al a

bso

rpti

on

Cep

hal

oth

in S

odiu

mR

atit

e30

-40

IM-I

VQ

IDG

1308

Cep

hra

din

eA

vian

35-5

0P

Oq4-

6hE

111,

147

3

Cep

hra

din

eC

ran

e10

0P

Oq4-

6hE

111

Cep

hra

din

eE

mu, p

igeo

n10

0P

Oq4-

6hE

1473

Ch

ito

san

Avi

an<

50

To

pic

alq3d

-q2w

B16

33R

inse

an

d a

pp

ly s

par

ingl

y to

wo

un

d s

urf

ace

or

pac

k su

pp

ura

tin

g w

oun

d, p

rom

ote

wo

un

d

hea

ling

Ch

lora

l H

yd

rate

Avi

an (

budge

riga

r, c

anar

y, c

hic

ken

,

cro

w, c

ran

e)

106.

5IM

PR

NB

1084

Add m

agn

esiu

m s

ulf

ate

+ p

ento

bar

bit

al

sodiu

m, r

educe

do

se 1

5 to

20%

in d

ebili

tate

d

bir

ds

Ch

lora

l Hyd

rate

Eag

le, G

old

en80

.9IM

PR

NB

1086

Ch

lora

l Hyd

rate

Fal

con

, Pra

irie

64IM

PR

NB

1086

Ch

lora

l Hyd

rate

G

ull

(Cal

ifo

rnia

, Lau

ghin

g,

Her

rin

g)

106.

5IM

PR

NB

1084

Ch

lora

l Hyd

rate

H

awk

(Mar

sh, R

ed-t

aile

d,

Swai

nso

n's

)

64-6

8IM

PR

NB

1086

Ch

lora

l Hyd

rate

O

wl,

Saw

-wh

et

106.

5 IM

P

RN

B

10

84

Ch

lora

l Hyd

rate

Pea

Fo

wl,

ph

easa

nt

106.

5IM

PR

NB

1084

Ch

lora

l Hyd

rate

Pig

eon

, sp

arro

w, t

ouca

net

106.

5IM

PR

NB

1084

Ch

lora

l Hyd

rate

Rai

l, W

oo

d10

6.5

IMP

RN

B10

84

Ch

lora

lose

An

seri

form

es0.

4-0.

48g/

L b

ait

Fee

dO

nce

G12

30A

dd d

iaze

pam

fo

r an

esth

esia

Ch

lora

lose

Bir

d, S

eed-e

ater

2 g/

kg g

rain

Fee

dO

nce

E4

Ch

lora

lose

Bla

ckb

ird, R

ed-w

inge

d0.

02-0

.025

mg

TD

Fee

dO

nce

G12

30A

dd s

eco

bar

bit

al

Ch

lora

lose

Cra

ne

1.54

-1.7

9 g/

L c

orn

Fee

dO

nce

G13

61

Ch

lora

lose

Duck

0.4-

0.5

g/L

bai

tF

eed

On

ceG

1386

Add d

iaze

pam

Ch

lora

lose

Duck

, Mal

lard

15F

eed

On

ceB

1095

Ch

lora

lose

Duck

, Mal

lard

40P

OP

RN

D14

01

Ch

lora

lose

Turk

ey8

g/L

co

rnF

eed

On

ceE

1386

Sedat

ion

in 4

0-60

min

, 9%

mo

rtal

ity

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 17: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 257

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Ch

lora

mp

hen

ico

lA

vian

50-1

00P

OQ

DE

704

Ch

lora

mp

hen

ico

lA

vian

200

mg

Neb

uliz

eT

DE

704

Dilu

te in

15

ml 0

.9%

sal

ine

solu

tio

n

Ch

lora

mp

hen

ico

lA

vian

50-1

00P

aren

tera

lQ

DE

704

Ch

lora

mp

hen

ico

lB

udge

riga

r50

IMB

IDA

394

Ch

lora

mp

hen

ico

lC

anar

y0.

1-0.

15 g

/L

Fee

dQ

DE

695

In s

oft

fo

od

Ch

lora

mp

hen

ico

lC

hic

ken

50IM

BID

A39

4

Ch

lora

mp

hen

ico

l C

on

ure

(N

anday

, Sun

)

50

IM

QID

A

39

4

Ch

lora

mp

hen

ico

lC

ran

e10

0SC

TID

A59

6

Ch

lora

mp

hen

ico

lD

uck

, Ch

ines

e10

0IM

-IV

QID

A50

8

Ch

lora

mp

hen

ico

lD

uck

, Ch

ines

e25

IM-I

Vq3h

A50

8

Ch

lora

mp

hen

ico

lD

uck

, Ch

ines

e24

0IM

-IV

TID

A50

8

Ch

lora

mp

hen

ico

lD

uck

, Musc

ovy

50IM

BID

A39

4

Ch

lora

mp

hen

ico

lE

agle

50IM

QD

A39

4

Ch

lora

mp

hen

ico

lG

oo

se, E

gyp

tian

50IM

BID

A39

4

Ch

lora

mp

hen

ico

lH

awk

50IM

BID

A39

4

Ch

lora

mp

hen

ico

lM

acaw

50IM

QID

A39

4

Ch

lora

mp

hen

ico

lO

stri

ch10

IMB

IDG

401

Do

ub

le d

osa

ge f

or

bir

ds

bel

ow

5 k

g

Ch

lora

mp

hen

ico

lO

wl,

Bar

red

50IM

BID

A39

4

Ch

lora

mp

hen

ico

lP

ea F

ow

l50

IMQ

DA

394

Ch

lora

mp

hen

ico

lP

igeo

n95

PO

QID

E11

1W

ith

gri

t in

die

t

Ch

lora

mp

hen

ico

lP

igeo

n50

PO

TID

E70

4

Ch

lora

mp

hen

ico

lP

igeo

n30

PO

QID

E14

73W

ith

out

grit

in d

iet

Ch

lora

mp

hen

ico

lP

igeo

n80

IMB

IDE

1650

Fo

r sa

lmo

nel

losi

s

Ch

lora

mp

hen

ico

lP

sitt

acin

e50

IM-I

VT

ID-Q

IDE

111

Ch

lora

mp

hen

ico

lR

apto

r50

IMT

IDE

1240

Ch

lora

mp

hen

ico

lR

atit

e35

-50

IM-I

V-P

O-

SC

TID

G13

08N

ot

for

foo

d a

nim

als

Ch

lora

mp

hen

ico

l

Palm

itate

Avi

an80

-100

Gav

age

BID

E74

1

Ch

lora

mp

hen

ico

l Pal

mit

ate

Avi

an50

PO

TID

G55

Ch

lora

mp

hen

ico

l Pal

mit

ate

Avi

an15

0-20

0P

OT

ID-Q

IDG

739

Fo

r la

rge

bir

ds

Ch

lora

mp

hen

ico

l Pal

mit

ate

Psi

ttac

ine

100

PO

BID

-QID

E74

1

Ch

lora

mp

hen

ico

l Pal

mit

ate

Turk

ey50

PO

QID

E74

1

Ch

lord

iazep

oxid

e H

Cl

Co

wb

ird, q

uai

l15

0 g/

kg f

oo

dF

eed

On

ceB

1094

An

esth

esia

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 18: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I258

DR

UG

NA

ME

S

PE

CIE

S

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Ch

lorh

exid

ine G

luco

nate

Avi

an2.

5 m

l/L

of

2%

solu

tio

n/L

Dri

nk

NL

E74

1F

or

can

did

iasi

s o

r an

tim

icro

bia

l pro

ph

ylax

is

Ch

lorh

exid

ine

Glu

con

ate

Avi

an2.

5-7.

5 m

l of

2%

solu

tio

n/L

Dri

nk

NL

E12

40P

reve

nt

or

trea

t m

ild in

test

inal

can

did

iasi

s

Ch

lorh

exid

ine

Glu

con

ate

Avi

an0.

5% s

olu

tio

nF

lush

NL

E12

40W

oun

d f

lush

Ch

lorh

exid

ine

Glu

con

ate

Avi

an0.

005

g/L

Dri

nk

QD

E14

92F

or

can

did

iasi

s

Ch

loro

qu

ine

Avi

an0.

4 g/

LD

rin

kQ

DE

1180

Fo

r b

loo

d p

aras

ites

Ch

loro

quin

eA

vian

10P

OT

IDG

57U

sual

ly in

co

mb

inat

ion

wit

h p

rim

aquin

e

Ch

loro

quin

eA

vian

10P

OQ

DG

61A

dd p

rim

aquin

e p

ho

sph

ate

Ch

loro

quin

eF

alco

n10

PO

On

ceB

1177

Add p

rim

aquin

e, f

ollo

w 1

st d

ose

wit

h 5

mg/

kg a

t h

ours

6,1

8 an

d 2

4

Ch

loro

quin

eP

asse

rin

e, S

mal

l2.

1 g/

LD

rin

kN

LE

1187

Th

erap

euti

c b

ut

no

t cu

rati

ve f

or

Pla

smod

ium

Ch

loro

quin

eP

engu

in5

PO

QID

E11

1, 1

240

Lo

adin

g do

sage

10

mg/

kg

Ch

loro

quin

eP

engu

in, A

fric

an5

PO

QD

B26

2

Ch

loro

quin

eR

apto

r5

NL

NL

D16

12

Ch

loro

quin

eR

apto

r25

IMQ

DE

1400

Pla

smod

ium

an

d L

euco

cyto

zoon

Ch

loro

quin

eR

apto

r10

PO

QD

G61

, 94

Add p

rim

aquin

e p

ho

sph

ate

Ch

lorp

rom

azin

eA

vian

0.01

25 g

/L

Dri

nk

NL

E14

92, 1

650

Fo

r fe

ath

er p

icki

ng

and a

nxi

ety

Ch

lort

etr

acycli

ne H

Cl

Am

azo

n, B

lue-

fro

nte

d2.

5 g/

kg c

orn

Fee

dQ

DA

230

Fo

r th

erap

y le

ss t

han

2 w

eeks

dura

tio

n

Ch

lort

etra

cycl

ine

HC

lA

maz

on

, Gre

en-c

hee

ked

2.5

- 5.

0 g/

kg f

oo

dF

eed

On

ceB

1062

Fo

r C

hlam

ydop

hila

Ch

lort

etra

cycl

ine

HC

lA

maz

on

s5

g/kg

fo

od

Fee

dQ

DB

1079

Fo

r C

hlam

ydop

hila

Ch

lort

etra

cycl

ine

HC

lA

vian

1 g/

LD

rin

kQ

DE

704

Pro

ph

ylac

tic

do

sage

Ch

lort

etra

cycl

ine

HC

lA

vian

5 g/

LD

rin

kQ

DE

704

Th

erap

euti

c do

sage

Ch

lort

etra

cycl

ine

HC

lA

vian

100

PO

QID

E70

4

Ch

lort

etra

cycl

ine

HC

lA

vian

0.5

g/L

Dri

nk

QD

E74

1F

or

chla

myd

op

hilo

sis

init

ial t

her

apy

Ch

lort

etra

cycl

ine

HC

lA

vian

100

IM-P

ON

LE

924

Ch

lort

etra

cycl

ine

HC

lA

vian

34IV

NL

F12

09

Ch

lort

etra

cycl

ine

HC

lB

udge

riga

r5

g/kg

see

dF

eed

QD

A73

1H

ulle

d m

edic

ated

mill

et

Ch

lort

etra

cycl

ine

HC

lB

udge

riga

r50

0 m

g/kg

fo

od

Fee

dQ

DE

565

An

tich

lam

ydo

ph

ilial

Ch

lort

etra

cycl

ine

HC

lC

anar

y1.

5 g/

kg f

oo

dF

eed

QD

E69

5

Ch

lort

etra

cycl

ine

HC

lC

hic

ken

2.5

g/L

Dri

nk

NL

A80

2A

dd c

hlo

rtet

racy

clin

e fe

ed a

lso

Ch

lort

etra

cycl

ine

HC

l C

hic

ken

2.

5 g/

kg f

oo

d F

eed

On

ce

A

802

Add c

hlo

rtet

racy

clin

e dri

nki

ng

wat

er a

lso

Ch

lort

etra

cycl

ine

HC

lC

hic

ken

20-6

0P

ON

LC

705

Ch

lort

etra

cycl

ine

HC

lC

hic

ken

220

mg/

kg f

oo

dF

eed

QD

E56

4N

o s

laugh

ter

wit

hdra

wal

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 19: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 259

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Ch

lort

etra

cycl

ine

HC

lC

ock

atie

l2.

4 g/

kg f

oo

dF

eed

QD

A73

8H

ulle

d m

illet

+ o

ats

for

chla

myd

op

hilo

sis

Ch

lort

etra

cycl

ine

HC

l C

ock

ato

o, G

Sulf

ur-

cres

ted

4.4

g/kg

fo

od

Fee

d

QD

B

10

79

Fo

r ch

lam

ydo

ph

ilosi

s

Ch

lort

etra

cycl

ine

HC

l C

on

ure

(M

aro

on

-bel

lied, N

anday

) 2.

4 g/

kg f

oo

d

Fee

d

QD

A

73

8 H

ulle

d m

illet

+ o

ats

for

chla

myd

op

hilo

sis

Ch

lort

etra

cycl

ine

HC

lF

inch

1 -

1.5

g/L

Dri

nk

QD

E15

72

Ch

lort

etra

cycl

ine

HC

lF

inch

1.5

g/kg

fo

od

Fee

dQ

DE

1572

Ch

lort

etra

cycl

ine

HC

lG

allif

orm

es30

Dri

nk

QD

E70

4

Ch

lort

etra

cycl

ine

HC

l L

ori

keet

0.

5 g/

kg f

ruit

F

eed

QD

A

10

77

Fo

r ch

lam

ydo

ph

ilosi

s

Ch

lort

etra

cycl

ine

HC

l L

ori

keet

0.

5 g/

L li

quid

fo

od

Fee

d

On

ce

A

1077

F

or

chla

myd

op

hilo

sis

Ch

lort

etra

cycl

ine

HC

l L

ory

(O

rnat

e, p

urp

le-n

aped

)

0.5g

/kg

liquid

fo

od

Fee

d

On

ce

A

1077

F

or

chla

myd

op

hilo

sis

Ch

lort

etra

cycl

ine

HC

l L

ove

bir

d, A

bys

sin

ian

2.

4 g/

kg f

oo

d

Fee

d

QD

A

73

8

Ch

lort

etra

cycl

ine

HC

lM

acaw

, Buff

on

's10

-15

g/kg

Fee

dO

nce

A78

1

Ch

lort

etra

cycl

ine

HC

l P

arak

eet

(Bo

urk

e's,

red

-fro

nt,

rin

g-

nec

ked)

2.4

g/kg

fo

od

Fee

dQ

DA

738

Hulle

d m

illet

+ o

ats

for

chla

myd

op

hilo

sis

Ch

lort

etra

cycl

ine

HC

lP

asse

rin

e1.

5 g/

kg s

oft

fo

od

Fee

dQ

DE

1437

Add d

rug

to d

rin

k at

th

e sa

me

tim

e, u

se f

or

30 d

ays

for

chla

myd

op

hilo

sis

Ch

lort

etra

cycl

ine

HC

l P

asse

rin

e 1.

0 -

1.5

g/L

D

rin

k Q

D

E

1437

A

dd d

rug

to f

oo

d a

t th

e sa

me

tim

e, u

se f

or

30 d

ays

for

chla

myd

op

hilo

sis

Ch

lort

etra

cycl

ine

HC

lP

igeo

n40

-50

PO

B-T

IDA

565

Wit

ho

ut

grit

in d

iet

Ch

lort

etra

cycl

ine

HC

lP

igeo

n10

0IM

QD

G23

2

Ch

lort

etra

cycl

ine

HC

lP

igeo

n50

PO

TID

-QID

G26

0W

ith

or

wit

ho

ut

tylo

sin

Ch

lort

etra

cycl

ine

HC

lP

igeo

n0.

5 g/

LD

rin

kQ

DG

590

Ch

ange

dai

ly

Ch

lort

etra

cycl

ine

HC

lP

oult

ry0.

106-

0.26

4 g/

LF

eed

QD

C56

4P

rop

hyl

acti

c

Ch

lort

etra

cycl

ine

HC

lP

oult

ry11

0-55

0 m

g/kg

fee

dF

eed

QD

C56

4

Ch

lort

etra

cycl

ine

HC

lP

sitt

acin

e2.

5-10

g/kg

fo

od

Fee

dQ

DA

693

Do

sage

bas

ed o

n w

eigh

t o

f fo

od

Ch

lort

etra

cycl

ine

HC

lR

apto

r33

PO

TID

E16

12F

or

chla

myd

op

hilo

sis

Ch

lort

etra

cycl

ine

HC

lR

atit

e15

-20

PO

TID

G13

08

Ch

lort

etra

cycl

ine

HC

lT

urk

ey2.

5 g/

LD

rin

kN

LA

802

Add c

hlo

rtet

racy

clin

e fe

ed a

lso

Ch

lort

etra

cycl

ine

HC

lT

urk

ey10

-30

PO

NL

C70

5

Ch

oli

ne

Avi

an50

0-13

00F

eed

QD

E14

70F

or

hep

atic

lip

ido

sis

Ch

rom

ium

Pic

oli

nate

Avi

an10

dro

ps/

kgP

OQ

DE

1435

Sto

ck s

olu

tio

n 1

pill

per

30

ml l

actu

lose

fo

r

dia

bet

es

Ch

rom

ium

Pic

olin

ate

Avi

an0.

1P

OB

IDE

1205

Cim

eti

din

eP

engu

in, A

fric

an35

PO

QD

G12

8

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 20: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I260

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Cip

rofl

oxacin

HC

lA

vian

80P

OQ

DD

1470

, 157

1A

dd e

tham

buto

l + r

ifam

pin

fo

r liv

er

myc

ob

acte

rio

sis

Cip

rofl

oxa

cin

HC

lA

vian

20P

OB

IDD

1571

Add c

lofa

zim

ine

+ c

yclo

seri

ne

+ e

tham

buto

l

for

avia

n m

yco

bac

teri

osi

s

Cip

rofl

oxa

cin

HC

lA

vian

10-1

5P

OB

IDG

1319

Cip

rofl

oxa

cin

HC

lC

anar

y20

PO

BID

G48

Cip

rofl

oxa

cin

HC

lC

hic

ken

5P

ON

LA

797

Cip

rofl

oxa

cin

HC

lC

ock

atie

l30

PO

BID

G44

Cip

rofl

oxa

cin

HC

lG

ull

20P

OQ

DE

1357

Cip

rofl

oxa

cin

HC

lH

awk,

Red

-tai

led

50P

OB

IDA

168

Cip

rofl

oxa

cin

HC

lO

stri

ch20

NL

BID

E62

8F

or

ovi

duct

infe

ctio

n

Cip

rofl

oxa

cin

HC

lP

igeo

n0.

25 g

/L

Dri

nk

QD

G59

0C

han

ge d

aily

Cip

rofl

oxa

cin

HC

lP

igeo

n5-

20P

OB

IDG

590

Cip

rofl

oxa

cin

HC

lP

sitt

acin

e20

-40

PO

BID

E11

1

Cip

rofl

oxa

cin

HC

lT

ouca

n, T

oco

10P

OB

IDG

1379

Cis

ap

rid

eA

vian

0.5-

1P

OT

IDE

1151

To

imp

rove

G

I m

oti

lity

Cis

apri

de

Psi

ttac

ine

1N

LB

IDG

1263

Fo

r ile

us

Cis

apri

de

Rap

tor

0.25

PO

TID

E14

00In

crea

se g

ut

mo

tilit

y

Cis

pla

tin

Mac

aw, B

lue

and G

old

0.3

mg/

cm3

P

aren

tera

l Q

W

G

1369

In

tral

esio

nal

-fib

rosa

rco

ma

Cit

ric A

cid

Avi

an0.

5 g/

LD

rin

kQ

DE

704

Add o

xyte

trac

yclin

e

Cit

ric

Aci

dP

asse

rin

e, S

mal

l1.

0 g/

LD

rin

kN

LE

1187

Cla

no

bu

tin

Psi

ttac

ine

0.2

PO

QD

G17

22L

iver

sup

po

rt

Cla

rith

rom

ycin

Avi

an85

PO

QD

G11

54A

dd e

tham

buto

l + r

ifab

uti

n, d

ose

allo

met

rica

lly f

or

myc

ob

acte

rio

sis

Cla

zu

ril

An

seri

form

es5-

10P

Oq3d

D11

50F

or

cocc

idio

sis

Cla

zuri

lP

igeo

n5-

10P

OQ

DG

57R

epea

t af

ter

2 day

s

Cla

zuri

lP

igeo

n6.

5P

OO

nce

G10

9

Cla

zuri

lP

igeo

n5

PO

NL

G10

9

Cla

zuri

lP

oult

ry5-

10P

OQ

DG

57R

epea

t af

ter

2 day

s

Cla

zuri

lP

sitt

acin

e7

PO

QD

E12

40W

ait

2 day

s th

en r

epea

t fo

r co

ccid

iosi

s

Cla

zuri

lR

apto

r5-

10P

Oq3d

E12

40F

or

cocc

idio

sis

Cli

nd

am

ycin

HC

lA

vian

100

PO

QD

D12

21F

or

clo

stri

dio

sis

Clin

dam

ycin

HC

lA

vian

150

PO

QD

E14

31F

or

ost

eom

yelit

is

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 21: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 261

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Clin

dam

ycin

HC

lE

agle

, Lit

tle

40P

OB

IDG

1568

Fo

r p

ost

-op

erat

ive

ort

ho

ped

ic s

urg

ery

Clin

dam

ycin

HC

lG

osh

awk,

Bro

wn

40P

OB

IDG

1568

Clin

dam

ycin

HC

lG

ull

100-

150

PO

QD

E13

57

Clin

dam

ycin

HC

lO

wl,

Bar

n40

PO

BID

G15

68

Clin

dam

ycin

HC

lO

wl,

Gre

at-h

orn

ed12

.5P

OB

IDG

173

Add e

nro

flo

xaci

n

Clin

dam

ycin

HC

lP

igeo

n10

0P

OQ

DA

1473

Clin

dam

ycin

HC

lP

igeo

n10

0P

OQ

DE

111

Clin

dam

ycin

HC

lP

sitt

acin

e10

0P

OQ

DE

1240

Fo

r o

steo

mye

litis

an

d t

endo

n s

hea

th

infe

ctio

ns

Clin

dam

ycin

HC

lP

sitt

acin

e50

NL

BID

F11

70U

sed t

o t

reat

an

aero

bic

ost

eom

yelit

is

Clin

dam

ycin

HC

lP

sitt

acin

e25

NL

TID

F11

70

Clin

dam

ycin

HC

lR

apto

r30

-40

PO

BID

B15

68

Clo

fazim

ine

Avi

an6

PO

QD

D14

70A

dd e

tham

buto

l + r

ifam

pin

fo

r liv

er

myc

ob

acte

rio

sis

Clo

fazi

min

eA

vian

1.5

PO

QD

D15

71

Clo

fazi

min

eP

sitt

acin

e1.

5P

OQ

DE

1240

Fo

r m

yco

bac

teri

osi

s

Clo

fazi

min

eR

apto

r1-

5P

OQ

DE

1240

, 115

4

Clo

mip

ram

ine H

Cl

Avi

an0.

5-1

NL

QD

-BID

D14

75C

on

tro

l of

self

-muti

lati

on

, mix

ed r

esult

s

Clo

mip

ram

ine

HC

lC

ock

ato

o3

PO

BID

G12

78C

loac

al p

rola

pse

Clo

mip

ram

ine

HC

lP

sitt

acin

e0.

5-1

PO

BID

B43

Clo

mip

ram

ine

HC

lP

sitt

acin

e0.

5-1

PO

QD

-BID

E11

1G

radual

ly in

crea

se d

ose

ove

r 4

to 5

day

s

Clo

pid

ol

Ch

icke

n12

5-25

0 m

g/kg

fo

od

Fee

dQ

DE

564

5-day

sla

ugh

ter

wit

hdra

wal

, pro

ph

ylac

tic

Clo

pid

ol

Po

ult

ry0.

25 g

/kg

fo

od

Fee

dQ

DC

564

Pro

ph

ylac

tic

Clo

rsu

lon

An

seri

form

es20

PO

q2w

D11

50F

or

cest

odes

an

d n

emat

odes

Clo

rsulo

nA

vian

20P

Oq2w

G81

8F

or

tap

ewo

rms

Clo

rsulo

nP

sitt

acin

e20

PO

q2w

E11

1

Clo

rsulo

nR

apto

r20

PO

q2w

E12

40F

or

trem

ato

des

an

d c

esto

des

Clo

trim

azo

leC

ran

e10

g/L

Neb

uliz

eT

IDE

1361

An

tifu

nga

l

Clo

trim

azo

leR

apto

r70

-100

g/L

Neb

uliz

eB

IDE

1359

Clo

xacil

lin

So

diu

mA

vian

100-

200

IMQ

DE

565

Clo

xaci

llin

So

diu

mA

vian

250

PO

BID

E12

34F

or

bum

ble

foo

t

Clo

xaci

llin

So

diu

mA

vian

100

PO

QD

E14

70

Clo

xaci

llin

So

diu

mR

apto

r25

0P

OB

IDE

1240

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 22: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I262

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Clo

xaci

llin

So

diu

mR

apto

r10

0-25

0IM

NL

E14

63F

or

bac

teri

al in

fect

ion

s

Co

en

zym

e Q

10A

vian

1P

OQ

D-B

IDE

1205

, 143

5F

or

hea

rt, g

eria

tric

, dia

bet

ic, i

mm

un

e

def

icie

nt

bir

ds

Co

lch

icin

eA

vian

0.04

PO

QD

D14

70F

or

hep

atic

fib

rosi

s

Co

lch

icin

eM

acaw

0.01

PO

BID

G45

Co

lch

icin

eP

sitt

acin

e0.

2P

OB

IDE

111,

147

3

Co

lch

icin

eP

sitt

acin

e0.

04P

OQ

D-B

IDE

1756

Co

rtic

otr

op

inA

vian

16 I

U T

DIM

On

ceB

88, 5

32

Cro

tam

ito

nP

sitt

acin

e10

%T

op

ical

NL

E12

40F

or

knem

ido

cop

tic

mit

es

Cu

pri

c S

ulf

ate

Avi

an51

% p

ow

der

To

pic

alP

RN

E12

40F

or

ulc

erat

ive

der

mat

itis

Cup

ric

Sulf

ate

Ost

rich

0.5

g/L

Dri

nk

QD

G12

54, 2

83F

or

can

did

iasi

s, u

se a

cidif

ied c

op

per

sulf

ate

Cup

ric

Sulf

ate

Psi

ttac

ine

1:20

00 d

iluti

on

T

op

ical

q2w

D

14

46

Fo

r der

mat

om

yco

sis

Cyan

oco

bala

min

Avi

an0.

25-0

.5IM

QW

E11

1

Cyclo

ph

osp

ham

ide

**C

hec

k cu

rren

t lit

erat

ure

pri

or

to u

se

Cyc

lop

ho

sph

amid

eO

wl,

Gre

at-h

orn

ed25

PO

On

ceF

125

Max

imum

do

sage

list

ed

Cyc

lop

ho

sph

amid

eP

sitt

acin

e20

0 m

g/m

2

IO

Q

W

E

1470

L

ymp

ho

sarc

om

a

Cyclo

seri

ne

Avi

an5

PO

BID

D15

71A

dd c

ipro

flo

xaci

n o

r en

rofl

oxa

cin

+

clo

fazi

min

e +

eth

amb

uto

l fo

r av

ian

myc

ob

acte

rio

sis

Cyc

lose

rin

eR

apto

r5

PO

BID

E12

40, 1

154

Cyclo

spo

rin

eD

uck

, Pek

in60

IVQ

DA

835

Cyc

losp

ori

ne

Duck

, Pek

in10

IVT

ID-Q

IDA

835

Cyp

erm

eth

rin

Pig

eon

0.05

% s

olu

tio

nT

op

ical

QD

E70

4A

pp

ly a

s sp

ray

Cyp

erm

eth

rin

Psi

ttac

ine

2.0%

so

luti

on

NL

NL

E12

40Sp

ray

pre

mis

es f

or

Der

man

yssu

s, a

void

co

nta

ct

wit

h s

kin

Cyp

erm

eth

rin

Rap

tor

2% s

olu

tio

nN

LN

LE

1240

Dan

ofl

oxacin

Mesy

late

Ch

icke

n0.

05 g

/L

Dri

nk

NL

A83

7F

or

Myc

opla

sma

galli

sept

icum

Dan

ofl

oxa

cin

Mes

ylat

eC

hic

ken

5P

OQ

DB

893,

990

Fo

r co

lisep

tice

mia

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 23: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 263

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Deco

qu

inate

Ch

icke

n30

mg/

kg f

oo

dF

eed

QD

E56

4N

o s

laugh

ter

wit

hdra

wal

, pro

ph

ylac

tic

Dec

oquin

ate

Ph

easa

nt,

Rin

g-n

ecke

d0.

03 g

/kg

fo

od

Fee

dQ

DB

895

Fo

r co

ccid

iosi

s

Defe

rip

ron

eT

ouca

n50

PO

BID

G12

80F

or

iro

n s

tora

ge d

isea

se, z

inc

sup

ple

men

tati

on

may

be

requir

ed

Defe

roxam

ine M

esy

late

Avi

an10

0SC

QD

D14

70T

o r

educe

live

r ir

on

leve

ls

Def

ero

xam

ine

Mes

ylat

eA

vian

20P

OO

nce

G87

Co

nti

nue

IM q

4h a

s n

eeded

Def

ero

xam

ine

Mes

ylat

eM

ynah

40IM

QD

G34

0R

epea

t qo

w f

or

seri

es o

f 10

tre

atm

ents

Def

ero

xam

ine

Mes

ylat

eT

ouca

n10

0SC

QD

G12

80F

or

iro

n s

tora

ge d

isea

se

Def

ero

xam

ine

Mes

ylat

eT

ouca

n1.

28 m

g/kc

alIM

QD

E11

80Ir

on

ch

elat

ion

Delm

ad

ino

ne A

ceta

teA

vian

1IM

NL

E14

34

Del

mad

ino

ne

Ace

tate

Pig

eon

6.67

IMN

LE

1432

Deto

mid

ine H

Cl

Avi

an0.

3IM

NL

G13

20

Det

om

idin

e H

Cl

Ch

icke

n0.

3IM

PR

NE

1573

Sedat

ion

Det

om

idin

e H

Cl

Ost

rich

0.3

IMP

RN

E15

73Se

dat

ion

Dexam

eth

aso

ne

Avi

an1-

2IM

NL

D15

33

Dex

amet

has

on

eA

vian

2-4

IMQ

DE

1431

Use

sp

arin

gly

Dex

amet

has

on

eA

vian

N/A

To

pic

alN

LE

1151

Add d

imet

hyl

sulf

oxi

de

for

clo

acal

or

ute

rin

e

pro

lap

se

Dex

amet

has

on

eC

ran

e, S

arus

0.5

IVO

nce

G10

87

Dex

amet

has

on

eF

alco

n2

IM-I

VO

nce

E10

27F

or

sho

ck, t

raum

a, t

oxi

c co

ndit

ion

s

Dex

amet

has

on

eH

ero

n, G

reat

Blu

e0.

5IV

On

ceG

1087

Dex

amet

has

on

eP

igeo

n0.

15-1

.5IM

-IV

BID

E14

32

Dex

amet

has

on

eP

igeo

n0.

3-3

IM-I

VB

IDE

1432

Fo

r sh

ock

Dex

amet

has

on

eP

sitt

acin

e2-

4IM

QD

-BID

E12

40

Dex

amet

has

on

eP

sitt

acin

e4

IM-S

CN

LG

632

Neo

nat

e do

sage

, sh

ock

or

sep

sis

Dex

amet

has

on

eR

apto

r2-

4IM

QD

E14

33U

se w

ith

gre

at c

are

Dex

amet

has

on

eR

apto

r0.

3-3

IMq2d

E12

40L

on

g-la

stin

g fo

rmula

tio

n, r

educe

infl

amm

ato

ry r

esp

on

se a

nd s

ho

ck

Dexam

eth

aso

ne S

od

ium

Ph

osp

hate

Am

azo

n, Y

ello

w-n

aped

1IM

q3-

7dG

1033

Dex

amet

has

on

e So

diu

m

Ph

osp

hat

e

An

seri

form

es2

IMQ

DE

1240

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 24: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I264

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Dex

amet

has

on

e So

diu

m

Ph

osp

hat

e

Avi

an2

IM-I

VO

nce

E11

51

Dex

amet

has

on

e So

diu

m

Ph

osp

hat

e

Bust

ard

2IM

QD

E12

40

Dex

amet

has

on

e So

diu

m

Ph

osp

hat

e

Psi

ttac

ine

2-4

IM-I

VN

LE

1688

Dex

amet

has

on

e So

diu

m

Ph

osp

hat

e

Rap

tor

2IM

QD

E12

40

Dextr

ose

Avi

anN

/A

To

pic

alP

RN

E11

51F

or

flush

ing

wo

un

ds

Dex

tro

seA

vian

50IV

-PO

-SC

NL

E12

40Is

oto

nic

fo

r h

ypo

glyc

emia

an

d d

ehyd

rati

on

,

IV s

low

ly

Dex

tro

seA

vian

50-1

00IV

NL

E11

1G

ive

slo

wly

Dex

tro

seA

vian

50IV

-PO

-SC

NL

E12

40

Dex

tro

seA

vian

50-1

00IV

NL

E14

73G

ive

slo

wly

Dex

tro

seA

vian

1IV

NL

G13

11F

or

hyp

ogl

ycem

ia, 5

0% s

olu

tio

n, m

ay b

e

del

eted

Dex

tro

seP

sitt

acin

e2

ml/

kgIV

NL

G63

2N

eon

ate

do

sage

, use

50%

so

luti

on

, slo

w

bo

lus

Dex

tro

seR

apto

r50

0-10

00IV

On

ceE

1400

Giv

e sl

ow

ly f

or

hyp

ogl

ycem

ia

Dia

triz

oate

Meg

lum

ine

Budge

riga

r 0.

2 m

l TD

IP

N

L

G

95

Go

iter

th

erap

y

Dia

triz

oate

Meg

lum

ine +

Dia

triz

oate

So

diu

m

Am

azo

n, D

oub

le Y

ello

w-h

ead

400

IVO

nce

D17

56F

or

IV e

xcre

tory

uro

grap

hy

Dia

zep

am

An

seri

form

es1

NL

PR

ND

1403

Add k

etam

ine

Dia

zep

amA

nse

rifo

rmes

1.2-

1.6

g/L

bai

tF

eed

On

ceG

1230

Add c

hlo

ralo

se

Dia

zep

amA

nse

rifo

rmes

0.5-

1IM

-IV

BID

-TID

E12

40C

on

tro

l sei

zure

s

Dia

zep

amA

vian

0.5-

1IM

NL

E11

20, 1

492

Fo

r se

izure

s re

late

d t

o le

ad t

oxi

cose

s

Dia

zep

amB

ird, A

quat

ic0.

6IM

-IV

PR

NE

1503

Dia

zep

amB

ird, A

quat

ic0.

5-1

IM-I

VP

RN

E15

59F

or

lead

po

iso

nin

g to

co

ntr

ol c

on

vuls

ion

s

Dia

zep

amC

ran

e0.

5-1

NL

PR

NE

1189

Fo

r tr

anquili

zati

on

4 t

o 6

ho

urs

Dia

zep

amC

ran

e0.

2-0.

5N

LP

RN

E11

89A

dd k

etam

ine

for

anes

thes

ia

Dia

zep

amD

uck

1.3-

1.7

g/kg

bai

tF

eed

On

ceG

1386

Add c

hlo

ralo

se

Dia

zep

amE

mu

0.6

IVP

RN

G28

3A

dd p

ento

bar

bit

al a

fter

1 h

our

Dia

zep

amE

mu

5IV

NL

E4

Sedat

ion

Dia

zep

amF

alco

n1.

2IV

PR

ND

1401

Add k

etam

ine

Dia

zep

amH

awk,

Ro

ugh

-leg

ged

1-1.

5IV

PR

NG

1092

Co

mb

ine

wit

h k

etam

ine

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 25: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 265

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Dia

zep

amK

estr

el2.

2IV

PR

ND

1401

Add k

etam

ine

Dia

zep

amO

stri

ch1

IVP

RN

D14

01Sm

oo

th a

nes

thes

ia r

eco

very

Dia

zep

amO

stri

ch5

PO

PR

NE

4St

andin

g se

dat

ion

Dia

zep

amO

stri

ch1-

2IV

PR

NG

481

Giv

e ju

st p

rio

r to

rec

ove

ry f

rom

tile

tam

ine/

zola

zep

am

Dia

zep

amO

wl

1IV

PR

ND

1401

Add k

etam

ine

Dia

zep

amP

asse

rin

e0.

5P

ON

LE

1439

An

xio

lyti

c an

d h

yper

ph

agic

fo

r w

ild f

ract

ious

spec

ies

Dia

zep

amP

igeo

n2.

5IM

PR

NE

1432

Add k

etam

ine,

20

to 3

0 m

inute

s dee

p

sedat

ion

Dia

zep

amP

igeo

n0.

5-1

IM-I

VP

RN

G59

0A

dd k

etam

ine

Dia

zep

amP

sitt

acin

e2.

5-4

PO

PR

NE

1473

Dia

zep

amP

sitt

acin

e0.

5-1

IM-I

O-I

VP

RN

E16

88

Dia

zep

amP

sitt

acin

e1-

1.5

IM-I

VP

RN

G82

4

Dia

zep

amR

apto

r1

IMP

RN

D14

01A

dd k

etam

ine

Dia

zep

amR

apto

r1-

1.5

IVP

RN

D15

33A

dd k

etam

ine

Dia

zep

amR

atit

e1

NL

PR

ND

1403

Add k

etam

ine

Dia

zep

amR

atit

e0.

1IM

PR

NE

4A

dd k

etam

ine

Dia

zep

amR

atit

e0.

2-0.

3IV

PR

NE

243

Add k

etam

ine

Dia

zep

amR

atit

e0.

3IV

PR

NG

418

Tra

nquili

zati

on

par

ticu

larl

y duri

ng

anes

thes

ia

reco

very

Dia

zep

amR

hea

5IV

NL

E4

Sedat

ion

Dia

zep

amSw

an1.

3-1.

7 g/

kg b

ait

Fee

dO

nce

G13

86A

dd c

hlo

ralo

se

Dib

uty

ltin

Dil

au

rate

Ch

icke

n20

0 m

g/kg

fo

od

Fee

dQ

DE

564

10 d

ay s

laugh

ter

wit

hdra

wal

Dib

uty

ltin

Dila

ura

teP

oult

ry37

4 m

g/kg

fo

od

Fee

dQ

DC

564

Dic

hlo

rop

hen

Pig

eon

100

mg/

TD

PO

q10

dG

232

Dic

hlo

rvo

sA

vian

N/A

IHQ

DE

704

Imp

regn

ated

str

ip, 3

0 m

³ m

inim

um

Dic

hlo

rvo

s St

rip

Kak

arik

iN

/A

IHQ

DG

1609

Fo

r K

nem

idoc

opte

s

Dic

lazu

ril

Ch

icke

n0.

5-1.

0 m

g/kg

fo

od

Fee

dQ

DG

564

Dic

lazu

ril

Cro

w10

PO

QD

D14

38D

ose

on

day

s 0,

1, 2

, 4, 6

, 8 a

nd 1

0 fo

r

toxo

pla

smo

sis

Dic

lazu

ril

Par

trid

ge, E

uro

pea

n g

rey

0.36

6F

eed

QD

B89

1F

or

Eim

eria

Dic

lazu

ril

Pas

seri

ne

10P

OQ

DG

1334

Giv

e o

n d

ays

0, 1

, 2, 4

, 6, 8

an

d 1

0

Dic

lazu

ril

Ph

easa

nt,

Rin

g-n

ecke

d0.

369

Fee

dQ

DB

891

Fo

r E

imer

ia

Dic

lazu

ril

Quai

l, Ja

pan

ese

0.29

-0.5

6F

eed

QD

B89

1

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 26: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I266

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Dic

lofe

nac S

od

ium

Pig

eon

12.5

mg/

TD

PO

NL

E12

40F

or

arth

riti

s

Die

thylc

arb

am

azin

e

Cit

rate

Rap

tor

50P

ON

LE

1463

An

thel

min

tic

Die

thyls

tilb

est

rol

Avi

an0.

025-

0.07

5IM

NL

E11

1

Die

thyl

stilb

estr

ol

Avi

an0.

1-0.

3IM

NL

E14

73

Dig

oxin

Am

azo

n, Y

ello

w-n

aped

0.02

PO

BID

G10

33

Dig

oxi

nA

vian

0.02

NL

NL

D14

70

Dig

oxi

nA

vian

0.01

PO

QD

-BID

E11

52

Dig

oxi

nA

vian

0.02

-0.0

5P

OQ

D-B

IDE

1152

Dig

oxi

nA

vian

0.00

33 g

/L

Dri

nk

QD

G13

23C

han

ge d

aily

Dig

oxi

nB

udge

riga

r0.

02P

OQ

DA

882

Dig

oxi

n

Spar

row

0.

02 P

O

QD

A

88

2

Dim

erc

ap

rol

Avi

an

2.5

IM

q4h

E

11

20, 1

236

Co

nti

nue

BID

fo

r 10

day

s (o

r lo

nge

r if

nee

ded

) fo

r le

ad t

oxi

cose

s

Dim

erca

pro

lA

vian

25-3

5P

OQ

D-q

2dE

1240

, 147

3G

ive

5 day

s p

er w

eek

for

lead

to

xico

sis

Dim

eth

yl

Su

lfo

xid

eA

vian

Dim

eth

yl S

ulf

oxi

de

Avi

an5

ml

Neb

uliz

eN

LE

704

Add t

ylo

sin

+ 1

0 m

l 0.9

% s

alin

e so

luti

on

Dim

eth

yl S

ulf

oxi

de

Avi

an10

ml/

LN

ebuliz

eT

ID-Q

IDE

1650

Add a

pp

rop

riat

e an

tim

icro

bia

l, ad

jun

ct t

o

par

ente

ral t

her

apy

for

air

sacc

ulit

is

Dim

eth

yl S

ulf

oxi

de

Avi

anO

intm

ent

To

pic

alN

LE

1650

Fo

r p

rola

pse

d p

hal

lus

Dim

eth

yl S

ulf

oxi

de

Avi

an1

ml/

kg 5

0 %

so

luti

on

PO

NL

G17

17A

lso

ap

ply

to

pic

ally

Dim

eth

yl S

ulf

oxi

de

Avi

an20

IMB

ID-T

IDG

861

Fo

r h

eavy

met

al p

ois

on

ing

Dim

eth

yl S

ulf

oxi

de

Ch

icke

nM

ix 5

0:50

To

pic

alN

LB

1342

Add b

up

ivac

ain

e, p

rep

are

50:5

0 so

luti

on

Dim

eth

yl S

ulf

oxi

de

Rap

tor

N/A

To

pic

alN

LE

1240

Red

uce

sw

ellin

g, v

ehic

le t

o c

arry

dru

gs

thro

ugh

ski

n p

arti

cula

rly

on

legs

Dim

eth

ylg

lycin

eA

vian

5P

OT

IDE

1205

Bra

in d

iso

rder

s

Dim

eth

ylgl

ycin

e A

vian

2-

4 P

O

QD

-BID

E

14

35

Imm

un

e an

d e

ner

gy b

oo

ster

Dim

etr

idazo

leA

vian

50P

OQ

DE

704

Dim

etri

daz

ole

A

vian

1.

25lm

llpo

wder

/LlllllllllD

rin

k N

L

E

741

Fo

r tr

ich

om

on

iasi

s, g

iard

iasi

s an

d

his

tom

on

iasi

s

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 27: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 267

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Dim

etri

daz

ole

Avi

an50

PO

NL

E92

4F

or

pro

tozo

a

Dim

etri

daz

ole

Avi

an30

Gav

age

On

ceE

1650

Fo

r tr

ich

om

on

iasi

s, g

iard

iasi

s an

d

his

tom

on

iasi

s

Dim

etri

daz

ole

Fin

ch0.

1 g/

LD

rin

kQ

DG

1334

Fo

r co

chlo

som

iasi

s

Dim

etri

daz

ole

Lo

rike

et0.

1 g/

LD

rin

kQ

DE

1479

Dim

etri

daz

ole

Pig

eon

0.4

g/L

Dri

nk

NL

A79

1

Dim

etri

daz

ole

Pig

eon

50P

OQ

WE

1432

Dim

etri

daz

ole

Pig

eon

20P

OQ

DG

232

Dim

etri

daz

ole

Po

ult

ry50

0 m

g/kg

fo

od

Fee

dQ

DC

564

Pro

ph

ylac

tic

Dim

etri

daz

ole

Po

ult

ry0.

5-1.

0 g/

LD

rin

kQ

DG

585

Dim

etri

daz

ole

Rap

tor

125

PO

NL

D16

12F

or

tric

ho

mo

nia

sis

Dim

etri

daz

ole

Rap

tor

100

PO

NL

E14

63F

or

tric

ho

mo

nia

sis

Din

ito

lmid

eC

hic

ken

40-1

87 m

g/kg

fo

od

Fee

dQ

DE

564

No

sla

ugh

ter

wit

hdra

wal

, pro

ph

ylac

tic

Din

op

rost

Tro

meth

am

ine

(Pro

stag

lan

din

F-2

a)

An

seri

form

es0.

02-0

.1IM

-To

pic

alO

nce

D11

50A

pp

ly t

o c

loac

al m

uco

sa t

op

ical

ly, e

gg

bin

din

g

Din

op

rost

Tro

met

ham

ine

An

seri

form

es0.

02-0

.1IM

On

ceE

1240

Fo

r eg

g b

indin

g

Din

op

rost

Tro

met

ham

ine

Avi

an0.

02-0

.1IM

On

ceE

1473

Als

o in

trac

loac

al

Din

op

rost

Tro

met

ham

ine

Ost

rich

5 m

g T

DP

aren

tera

lO

nce

G12

24F

or

case

ous

salp

ingi

tis,

add a

pp

rop

riat

e

anti

mic

rob

ials

fo

r 1

wee

k

Din

op

rost

Tro

met

ham

ine

Psi

ttac

ine

0.02

-0.1

Ven

tO

nce

E12

40A

pp

ly t

o c

loac

al m

uco

sa f

or

egg

bin

din

g

Din

op

rost

Tro

met

ham

ine

Psi

ttac

ine

0.02

-0.1

IMO

nce

E12

40F

or

egg

bin

din

g

Din

op

rost

Tro

met

ham

ine

Rap

tor

0.02

-0.1

Ven

tO

nce

E12

40

Din

op

rost

on

e

(Pro

stag

lan

din

E)

Avi

an0.

2V

ent

NL

E14

74P

rece

de

wit

h c

alci

um

glu

con

ate

for

egg

bin

din

g, a

pp

ly in

to c

loac

a, m

ay a

dd v

itam

in E

+ s

elen

ium

Din

op

rost

on

eC

ock

atie

l0.

02V

ent

On

ceG

1699

Fo

r eg

g b

indin

g

Dip

hen

hyd

ram

ine H

Cl

Avi

an2

ION

LE

1470

Giv

e b

efo

re a

spar

agin

ase

and d

oxo

rub

icin

to

min

imiz

e an

aph

ylax

is

Dip

hen

hyd

ram

ine

HC

lA

vian

4IM

TID

E15

54F

or

anti

cho

lines

tera

se t

oxi

city

Dip

hen

hyd

ram

ine

HC

lA

vian

2-4

PO

BID

D14

75C

on

tro

l of

self

-muti

lati

on

Dip

hen

hyd

ram

ine

HC

lA

vian

2-4

NL

BID

E14

77F

or

feat

her

, sutu

re a

nd b

andag

e p

icki

ng

Dip

hen

hyd

ram

ine

HC

lP

sitt

acin

e2-

4P

OB

IDE

1473

Dip

hen

hyd

ram

ine

HC

lR

apto

r4

IMT

IDG

50

Dip

ren

orp

hin

eC

asso

war

y, D

oub

le-w

attl

ed2

mg/

mg

eto

rph

ine

NL

PR

ND

1401

Eto

rph

ine

anta

gon

ist

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 28: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I268

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Dip

ren

orp

hin

eO

stri

ch0.

05-0

.06

IVP

RN

B44

7O

pio

id a

nta

gon

ist

Dip

ren

orp

hin

eO

stri

ch4.

5-24

mg

TD

IMP

RN

G48

1R

ever

se e

torp

hin

e

Do

cu

sate

So

diu

mP

sitt

acin

e0.

3 g/

LD

rin

kN

LE

763

To

aid

in e

xpel

ling

lead

or

pre

ven

t

con

stip

atio

n f

ollo

win

g cl

oac

al s

urg

ery

Do

xap

ram

HC

lA

nse

rifo

rmes

10IV

On

ceD

1150

Stim

ula

nt

Do

xap

ram

HC

lA

vian

5-10

IM-I

VO

nce

E11

1, 1

473

Do

xap

ram

HC

lA

vian

5IM

-IO

-IV

NL

E24

3

Do

xap

ram

HC

lA

vian

6IV

NL

G49

6

Do

xap

ram

HC

lA

vian

20IM

-IO

-IV

NL

E11

83A

lso

dro

p o

nto

to

ngu

e fo

r ca

rdia

c ar

rest

Do

xap

ram

HC

lF

alco

n10

IM-I

VO

nce

E10

27

Do

xap

ram

HC

lO

stri

ch0.

5-1.

5IV

PR

NG

522

Do

xap

ram

HC

lP

sitt

acin

e20

IM-I

O-I

VN

LE

1688

Do

xap

ram

HC

lR

apto

r10

IM-I

VO

nce

E12

40

Do

xap

ram

HC

lR

apto

r5-

20IT

-IV

On

ceE

1359

Fo

r an

esth

etic

em

erge

nci

es

Do

xep

in H

Cl

Avi

an0.

5-1

PO

BID

E11

1C

on

tro

l fea

ther

pic

kin

g

Do

xep

in H

Cl

Avi

an0.

5P

OB

IDE

704

Or

add t

o d

rin

kin

g w

ater

Do

xo

rub

icin

**C

hec

k cu

rren

t lit

erat

ure

pri

or

to u

se

Do

xoru

bic

inA

vian

30 m

g/m

2IO

q3w

E14

70G

ive

30 m

g/m

² o

f b

ody

surf

ace

for

lym

ph

osa

rco

ma

Do

xycycli

ne

Am

azo

n P

arro

t1

g/kg

fo

od

Fee

dQ

DA

693

Do

xycycli

ne** R

efe

ren

ces

foll

ow

ed

by *

* a

re b

ase

d

on

th

e l

on

g a

cti

ng

form

ula

)

Avi

an10

0IM

QW

A55

Euro

pea

n f

orm

ula

tio

n.

Fo

r

chla

myd

op

hilo

sis,

may

be

spac

ed 5

to

7 d

ays

for

firs

t 4

wee

ks

Do

xycy

clin

eA

maz

on

Par

rot

40-5

0P

OQ

D-B

IDE

111

Do

xycy

clin

e**

Am

azo

n P

arro

t 10

0IM

q5d

-QW

A23

0F

or

chla

myd

op

hilo

sis

Do

xycy

clin

e**

Am

azo

n50

IMq4-

5dB

1062

Do

xycy

clin

eA

nse

rifo

rmes

0.24

g/kg

fo

od

Fee

dQ

DD

1150

Do

xycy

clin

eA

nse

rifo

rmes

50P

OB

IDD

1150

Fo

r ch

lam

ydo

ph

ilosi

s

Do

xycy

clin

e**

Avi

an10

0IM

q10

dB

583

Do

xycy

clin

eA

vian

15D

rin

kQ

DC

705

Do

xycy

clin

e**

Avi

an75

-100

IM-S

Cq5d

-QW

E56

5A

nti

chla

myd

op

hili

al

Do

xycy

clin

e**

Avi

an75

-100

IMq5d

E70

3F

or

chla

myd

op

hilo

sis,

may

be

spac

ed 5

to

7

day

s fo

r fi

rst

4 w

eeks

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 29: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 269

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Do

xycy

clin

eB

ird, A

quat

ic25

-50

PO

QD

E15

03B

road

sp

ectr

um

, fo

od f

or

resp

irat

ory

infe

ctio

ns,

tre

at f

or

45 d

ays

for

chla

myd

op

hila

Do

xycy

clin

e B

ird, A

quat

ic

10 g

/L

D

rin

k Q

D

E

1503

S

ee a

bo

ve

Do

xycy

clin

e**

Bir

d, A

quat

ic

75-1

00

IM

QW

E

15

03 S

ee a

bo

ve

Do

xycy

clin

e**

Bust

ard, H

oub

ara

100

IM

QW

A

12

40 S

ee a

bo

ve

Do

xycy

clin

eB

ust

ard, H

oub

ara

22-4

4IV

On

ceA

1240

Co

nti

nue

ther

apy

wit

h I

M o

r P

O d

osa

ge f

or

seve

re c

hla

myd

op

hilo

sis

Do

xycy

clin

eC

hic

ken

20P

OQ

DA

762

Do

xycy

clin

eC

hic

ken

0.1

g/L

Dri

nk

NL

A80

3

Do

xycy

clin

eC

hic

ken

10D

rin

kQ

DB

1009

Fo

r fo

wl c

ho

lera

Do

xycy

clin

eC

ock

atie

l0.

83 g

/L

Dri

nk

QD

A16

38F

or

chla

myd

op

hilo

sis

Do

xycy

clin

eC

ock

atie

l0.

5 g/

kg s

eed

Fee

dQ

DA

1638

Fo

r ch

lam

ydo

ph

ilosi

s, m

ay c

ause

to

xico

sis

Do

xycy

clin

eC

ock

atie

l1

g/kg

mas

hF

eed

QD

A16

38F

or

chla

myd

op

hilo

sis

Do

xycy

clin

e**

Co

ckat

iel

100

IMq10

dA

1638

Fo

r ch

lam

ydo

ph

ilosi

s, m

ay n

ot

mai

nta

in

adeq

uat

e dru

g p

lasm

a le

vels

Do

xycy

clin

e C

ock

atie

l 40

-50

PO

Q

D

E

111,

703

F

or

chla

myd

op

hilo

sis

Do

xycy

clin

eC

ock

ato

o1

g/kg

fo

od

Fee

dQ

DA

693

Do

xycy

clin

eC

ock

ato

o, G

off

in25

PO

BID

A69

7

Do

xycy

clin

eC

ock

ato

o, G

off

in0.

4 g/

LD

rin

kN

LA

749

Do

xycy

clin

eC

ock

ato

o, G

off

in1

g/kg

mas

hF

eed

QD

A16

39

Do

xycy

clin

eM

acaw

25P

OB

IDA

697

Do

xycy

clin

eM

acaw

, Blu

e an

d G

old

1 g/

kg c

orn

mas

hF

eed

QD

A73

0E

ach

bir

d f

ed 1

00 g

mas

h

Do

xycy

clin

eO

stri

ch10

NL

BID

E62

8O

viduct

al in

fect

ion

th

erap

y

Do

xycy

clin

eP

arro

t, G

rey

25P

OB

IDA

697

Do

xycy

clin

eP

arro

t, G

rey

0.4

g/L

Dri

nk

NL

A74

9

Do

xycy

clin

eP

arro

t, G

rey

1 g/

kg f

oo

dF

eed

QD

A16

39

Do

xycy

clin

eP

asse

rin

e0.

25 g

/L

Dri

nk

QD

E14

37A

dd d

rug

to f

oo

d a

t th

e sa

me

tim

e, u

se f

or

30 d

ays

for

chla

myd

op

hilo

sis

Do

xycy

clin

eP

asse

rin

e1

g/kg

fo

od

Fee

dQ

DE

1437

Add d

rug

to d

rin

k at

th

e sa

me

tim

e, u

se f

or

30 d

ays

for

chla

myd

op

hilo

sis

Do

xycy

clin

eP

engu

in10

NL

QD

G13

53F

or

bab

esio

sis

Do

xycy

clin

eP

engu

in, A

fric

an20

PO

BID

G13

53

Do

xycy

clin

e **

Pig

eon

75IM

On

ceA

379

Do

xycy

clin

e**

Pig

eon

75-1

00IM

-SC

q5d

-QW

A56

5

Do

xycy

clin

eP

igeo

n25

PO

BID

A56

5W

ith

gri

t in

die

t

Do

xycy

clin

eP

igeo

n15

Dri

nk

QD

C70

4

Do

xycy

clin

eP

oult

ry0.

05 g

/L

Dri

nk

QD

C56

4

Do

xycy

clin

eP

oult

ry0.

25-0

.5 g

/L

Dri

nk

QD

G58

5A

dd t

ylo

sin

, an

tim

yco

pla

smal

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 30: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I270

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Do

xycy

clin

eP

sitt

acin

e25

-50

IVN

LE

111

Do

xycy

clin

e**

Psi

ttac

ine

100

IMQ

WE

632

Neo

nat

e do

sage

Do

xycy

clin

eP

sitt

acin

e50

PO

QD

E63

2N

eon

ate

do

sage

Do

xycy

clin

e **

Psi

ttac

ine

20IV

On

ceE

632

Neo

nat

e do

sage

Do

xycy

clin

eR

apto

r50

IMN

LB

1568

Do

xycy

clin

eR

apto

r25

PO

BID

G94

Juve

nile

do

sage

Do

xycy

clin

eR

atit

e2-

3.5

PO

BID

G13

08F

or

chla

myd

op

hilo

sis

Do

xycy

clin

e H

ycla

teA

vian

0.4

g/L

Dri

nk

QD

A70

3F

or

chla

myd

op

hilo

sis

Do

xycy

clin

e H

ycla

teA

vian

200-

400

mg/

kg f

oo

dF

eed

QD

E56

5A

nti

chla

myd

op

hili

al

Do

xycy

clin

e H

ycla

teC

ock

atie

l0.

2-0.

4 g/

LD

rin

kQ

DA

703

Fo

r ch

lam

ydo

ph

ilosi

s

Do

xycy

clin

e H

ycla

teC

ock

ato

o, G

off

in0.

8 g/

LD

rin

kQ

DA

703

Do

xycy

clin

e H

ycla

teP

arro

t, G

rey

0.8

g/L

Dri

nk

QD

A70

3

Do

xycy

clin

e H

ycla

teP

igeo

n55

PO

BID

G47

Ed

eta

te C

alc

ium

Dis

od

ium

An

seri

form

es10

-40

IM-I

VB

IDD

1150

Fo

r le

ad p

ois

on

ing

Edet

ate

Cal

cium

Dis

odiu

mA

vian

30-5

0IM

-IV

QID

D12

21F

or

lead

or

zin

c to

xico

sis,

may

use

in

con

jun

ctio

n w

ith

pen

icill

amin

e

Edet

ate

Cal

cium

Dis

odiu

mA

vian

20-4

0IM

-IV

BID

D14

70T

o r

educe

live

r le

ad a

nd z

inc

Edet

ate

Cal

cium

Dis

odiu

mA

vian

20-4

0IM

BID

-TID

E11

1

Edet

ate

Cal

cium

Dis

odiu

mB

ird, A

quat

ic35

IMB

IDD

1478

Giv

e 3

to 4

day

s p

er w

eek

for

lead

po

iso

nin

g

Edet

ate

Cal

cium

Dis

odiu

mC

ran

e, S

and H

ill35

IMB

IDB

1088

Rep

eat

4 day

s la

ter

for

lead

po

iso

nin

g

Edet

ate

Cal

cium

Dis

odiu

mL

ory

, Ch

atte

rin

g30

SCB

IDG

42

Edet

ate

Cal

cium

Dis

odiu

mM

acaw

35IM

BID

G40

Edet

ate

Cal

cium

Dis

odiu

mP

igeo

n30

IMB

IDG

590

Edet

ate

Cal

cium

Dis

odiu

mP

sitt

acin

e10

-40

IVB

IDE

1240

Lea

d a

nd h

eavy

met

al p

ois

on

ing

Edet

ate

Cal

cium

Dis

odiu

mR

apto

r35

-50

NL

BID

E11

88F

or

lead

to

xici

ty

Edet

ate

Cal

cium

Dis

odiu

mR

apto

r10

-40

IM-I

VB

IDE

1240

Lea

d a

nd h

eavy

met

al p

ois

on

ing

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 31: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 271

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

En

ilco

nazo

leA

vian

2 g/

L N

aCl

To

pic

alN

LE

924

Fo

r sk

in m

yco

sis

En

ilco

naz

ole

Psi

ttac

ine

2 g/

L N

aCl

Neb

uliz

eB

IDG

1034

Dilu

te 1

00 m

g/m

l 1:5

0 in

no

rmal

sal

ine

En

ilco

naz

ole

Psi

ttac

ine

0.1-

1% s

olu

tio

nIT

NL

E12

40

En

ilco

naz

ole

Rap

tor

5IT

QD

E12

40D

ilute

1:1

0

En

ilco

naz

ole

Rap

tor

0.2%

so

luti

on

To

pic

alB

IDE

1240

En

ilco

naz

ole

Rat

ite

10%

so

luti

on

Flu

shN

LG

1224

Fo

r m

yco

tic

der

mat

osi

s

En

rofl

oxacin

Am

azo

n P

arro

t7.

5-15

IM-P

OQ

D-B

IDA

1473

En

rofl

oxa

cin

Am

azo

n15

IMQ

DA

749

En

rofl

oxa

cin

Am

azo

n, B

lue-

fro

nte

d0.

5 m

g/kg

fo

od

Fee

dO

nce

A85

8F

or

chla

myd

op

hila

En

rofl

oxa

cin

Am

azo

n, R

ed L

ore

d10

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700

2.5%

co

nce

ntr

atio

n

En

rofl

oxa

cin

An

seri

form

es10

-15

IM-P

OB

IDD

1150

, 135

8

En

rofl

oxa

cin

Ara

cari

, Bla

ck-n

ecke

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BID

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re-s

urg

ical

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rofl

oxa

cin

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15IM

-PO

-SC

QD

-BID

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6

En

rofl

oxa

cin

Avi

an30

PO

NL

E14

92F

or

Myc

opla

sma,

Chl

amyd

ophi

la

En

rofl

oxa

cin

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an10

g/L

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uliz

eT

ID-Q

IDE

1650

Add d

imet

hyl

sulf

oxi

de,

adju

nct

to

par

ente

ral

ther

apy

for

air

sacc

ulit

is

En

rofl

oxa

cin

Avi

an0.

25-1

g/kg

fo

od

Fee

dQ

DF

916

En

rofl

oxa

cin

A

vian

0.

05-0

.5 g

/L

D

rin

k N

L

F

916

En

rofl

oxa

cin

Avi

an15

PO

QD

G58

0A

dd e

tham

buto

l + r

ifam

pin

,

anti

myc

ob

acte

rial

En

rofl

oxa

cin

Bir

d, A

quat

ic30

IMB

IDE

1478

Po

st-t

raum

a in

fect

ion

s

En

rofl

oxa

cin

Budge

riga

r30

Fee

dO

nce

A92

0F

or

chla

myd

op

hilo

sis

En

rofl

oxa

cin

Bust

ard, H

oub

ara

15-3

0IM

-IV

-PO

BID

A79

0

En

rofl

oxa

cin

Ch

icke

n10

Dri

nk

NL

A81

1

En

rofl

oxa

cin

Duck

, Musc

ovy

15D

rin

kQ

DB

842

Puls

e do

se f

or

4 h

ours

eac

h d

ay

En

rofl

oxa

cin

Duck

, Pek

in10

Dri

nk

QD

A85

4F

or

Pas

teur

ella

an

d c

olif

orm

s

En

rofl

oxa

cin

Gull

10IM

BID

E13

57

En

rofl

oxa

cin

Haw

k, R

ed-t

aile

d5

IVQ

DA

978

En

rofl

oxa

cin

Ho

rnb

ill, G

reat

10-2

0P

OB

IDG

1587

En

rofl

oxa

cin

Lo

ry, R

ed15

PO

BID

G16

21

En

rofl

oxa

cin

Ost

rich

PO

TID

G41

8

En

rofl

oxa

cin

Ow

l, G

reat

-ho

rned

5IM

-PO

BID

G17

3A

dd c

lindam

ycin

or

cep

hal

oth

in

En

rofl

oxa

cin

Par

rot,

Gre

y0.

5 g/

LD

rin

kQ

DA

921

Fo

r sa

lmo

nel

losi

s

En

rofl

oxa

cin

Par

rot,

Gre

y0.

5 g/

kg f

oo

dF

eed

On

ceA

921

Hig

her

blo

od le

vels

in n

eon

ates

En

rofl

oxa

cin

Pen

guin

, Ro

ckh

op

per

9P

OQ

DG

1646

En

rofl

oxa

cin

Ph

easa

nt

20IM

-PO

NL

G67

8

En

rofl

oxa

cin

Ph

easa

nt,

Ch

ines

e R

ingn

eck

7.5

IMQ

DG

1296

Co

nti

nue

ther

apy

ora

lly

En

rofl

oxa

cin

Pig

eon

15IM

-SC

QD

A17

9

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 32: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I272

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

En

rofl

oxa

cin

Pig

eon

10P

OQ

DA

179

En

rofl

oxa

cin

Pig

eon

5-10

IM-I

V-P

O-

SC

QD

-BID

A86

6

En

rofl

oxa

cin

Pig

eon

10-2

0IM

-PO

-SC

QD

-BID

A91

9

En

rofl

oxa

cin

Pig

eon

5D

rin

kQ

DA

919

En

rofl

oxa

cin

Pig

eon

5P

OB

IDA

1473

En

rofl

oxa

cin

Po

ult

ry15

NL

BID

G58

5

En

rofl

oxa

cin

Psi

ttac

ine

2.5-

20P

OQ

DA

179

En

rofl

oxa

cin

Psi

ttac

ine

11-1

7.5

Dri

nk

NL

B75

0

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rofl

oxa

cin

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ttac

ine

10-2

0IM

NL

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2N

eon

ate

do

sage

, may

cau

se jo

int

def

ects

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oxa

cin

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tor

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-PO

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road

sp

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um

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g P

seud

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as,

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a

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cin

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ite

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or

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m n

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ive

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ctio

ns

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hri

ne

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an0.

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-IP

-IT

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NL

E14

73

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oeti

n A

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r an

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on

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e M

ale

ate

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an0.

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ceE

111,

147

3, 1

650

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r w

ith

out

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ium

glu

con

ate

for

egg

bin

din

g

Ery

thro

mycin

Avi

an0.

125

g/L

Dri

nk

NL

E11

1

Ery

thro

myc

inA

vian

25IM

QD

E56

5

Ery

thro

myc

inA

vian

100

PO

NL

E70

4

Ery

thro

myc

inA

vian

200

mg/

kgF

eed

QD

E70

4So

ft f

oo

d

Ery

thro

myc

inA

vian

10-2

0 g/

LN

ebuliz

eT

DE

704

Dilu

ted in

15

ml 0

.9%

sal

ine

solu

tio

n

Ery

thro

myc

inC

hic

ken

0.10

2 g/

LD

rin

kQ

DA

544

Ch

ick

do

sage

Ery

thro

myc

inF

inch

0.2

g/kg

fo

od

Fee

dQ

DE

1572

Ery

thro

myc

inF

inch

0.12

5 g

/L

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nk

QD

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72

Ery

thro

myc

inP

igeo

n10

0P

ON

LA

1055

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thro

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n2.

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LD

rin

kQ

DE

704

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thro

cin

So

lub

le®

, 5 g

per

tea

spo

on

Ery

thro

myc

inP

oult

ry0.

25 g

/L

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dQ

DC

564

Ery

thro

myc

inP

oult

ry10

-20

Dri

nk

QD

C70

5

Ery

thro

myc

inP

oult

ry50

-100

NL

BID

G58

5

Ery

thro

myc

inP

sitt

acin

e44

-88

PO

BID

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1F

or

sin

usi

tis

Ery

thro

myc

inP

sitt

acin

e10

-20

PO

BID

E12

40F

or

myc

op

lasm

al s

inusi

tis

and a

ir s

accu

litis

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thro

myc

inP

sitt

acin

e10

-20

Par

ente

ral-

PO

BID

E14

73

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 33: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 273

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Ery

thro

myc

inR

atit

e5-

10P

OT

IDG

1308

Est

rad

iol

Avi

an10

-15

IMQ

WB

677

Induce

mo

ltin

g X

4 w

eeks

Eth

am

bu

tol

HC

lA

maz

on

, Yel

low

-ch

eeke

d30

NL

QD

G71

3A

dd r

ifam

pin

+ is

on

iazi

d

Eth

amb

uto

l HC

lA

vian

30P

OQ

DD

1470

Eth

amb

uto

l HC

lA

vian

15P

OB

IDE

1473

Eth

amb

uto

l HC

lA

vian

30P

OQ

DE

1650

Add e

nro

flo

xaci

n +

rif

abuti

n f

or

myc

ob

acte

rio

sis

Eth

amb

uto

l HC

lA

vian

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OB

IDG

55A

dd r

ifam

pin

+ s

trep

tom

ycin

fo

r

myc

ob

acte

rio

sis

Eth

amb

uto

l HC

lC

ran

e, W

ho

op

ing

30P

OQ

DG

207

Add r

ifam

pin

Eth

amb

uto

l HC

lP

sitt

acin

e15

-20

PO

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40F

or

myc

ob

acte

rio

sis

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amb

uto

l HC

lR

apto

r20

PO

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40

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ine

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ub

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azin

e

Eto

rph

ine

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rich

0.04

-0.0

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Add a

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e

Eto

rph

ine

Ost

rich

0.04

IMP

RN

B44

7A

dd a

cep

rom

azin

e +

xyl

azin

e

F10

Avi

an1:

250

dilu

tio

nN

ebuliz

eQ

D-B

IDG

1197

Neb

uliz

e as

an

tifu

nga

l, an

tich

lam

ydo

ph

ilial

and a

nti

bac

teri

al

F10

Avi

an1:

200

dilu

tio

nT

op

ical

QD

G13

02D

aily

sp

ray

on

to f

eath

ers

for

yeas

t an

d

sup

ple

men

t to

fea

ther

pic

kin

g th

erap

y

F10

Avi

an1:

125

dilu

tio

nN

ebuliz

eT

IDB

1465

F10

Avi

an1:

125

Dilu

tio

nN

ebuliz

eB

IDG

1268

Add o

meg

a in

terf

ero

n, p

reve

nts

sec

on

dar

y

infe

ctio

n

F10

Rap

tor

1:25

0 D

iluti

on

Neb

uliz

eB

ID-T

IDG

742

Add it

raco

naz

ole

, 15

to 3

0 m

inute

s p

er d

ay

for

mild

asp

ergi

llosi

s

Fatt

y A

cid

s, O

meg

aP

sitt

acin

e0.

22 m

l/kg

PO

NL

E17

56A

dd a

spir

in, u

se <

6:1

rat

io o

meg

a 6:

om

ega

3, u

se u

nti

l ren

al h

isto

logy

no

rmal

izes

fo

r

ren

al d

isea

se

Fat

ty A

cids,

Om

ega

Psi

ttac

ine

0.11

ml/

kgP

OQ

DG

1263

Mix

5:1

N-6

:N-3

om

ega

fatt

y ac

ids

for

glo

mer

ulo

nep

hri

tis

or

acute

pan

crea

titi

s

Feb

an

tel

Ost

rich

20N

LN

LC

283

Feb

ante

lO

stri

ch5

PO

NL

G48

1

Feb

ante

lP

igeo

n30

PO

q3w

A88

8F

or

asca

rids

and c

apill

aria

Fen

ben

dazo

leA

nse

rifo

rmes

20P

OO

nce

D11

50C

on

tro

l nem

ato

des

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 34: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I274

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Fen

ben

daz

ole

An

seri

form

es5-

10P

OQ

DE

111,

147

3

Fen

ben

daz

ole

Avi

an25

NL

QD

D12

21R

epea

t in

2 w

eeks

fo

r ca

pill

aria

sis

Fen

ben

daz

ole

Avi

an10

0N

Lq2w

D12

21F

or

cap

illar

iasi

s

Fen

ben

daz

ole

Avi

an2

PO

QD

D14

70F

or

liver

par

asit

ic d

isea

se

Fen

ben

daz

ole

Avi

an20

-50

PO

q10

dE

111

Fo

r as

cari

ds

Fen

ben

daz

ole

Avi

an20

-50

PO

QD

E11

1F

or

fluke

s an

d c

apill

aria

Fen

ben

daz

ole

Avi

an50

PO

QD

E16

17F

or

asca

rids,

may

nee

d 5

-day

tre

atm

ent

for

cap

illar

ia, r

epea

t in

2 w

eeks

,

Fen

ben

daz

ole

Avi

an20

-100

PO

On

ceG

57A

void

duri

ng

bre

edin

g se

aso

n a

nd m

olt

ing

Fen

ben

daz

ole

Bir

d, A

quat

ic22

NL

NL

E14

78

Fen

ben

daz

ole

Bir

d, A

quat

ic50

PO

QD

E15

03R

epea

t in

2 w

eeks

fo

r as

cari

ds

Fen

ben

daz

ole

Bir

d, A

quat

ic10

0P

Oq2w

E15

03

Fen

ben

daz

ole

Bust

ard

30P

OO

nce

E12

40

Fen

ben

daz

ole

Bust

ard, H

oub

ara

25P

OO

nce

G93

2P

rop

hyl

axis

fo

r ro

un

d w

orm

s

Fen

den

daz

ole

Co

ckat

iels

N/A

GM

ay h

ave

leth

al r

eact

ion

Fen

ben

daz

ole

Cra

ne

100

PO

QD

E62

9R

epea

t q2w

as

nee

ded

Fen

ben

daz

ole

Cra

ne

50-1

00P

OQ

DE

1361

Rep

eat

in 2

wee

ks f

or

gap

ewo

rms

and

cap

illar

ids

Fen

ben

daz

ole

Fal

con

20P

OQ

DE

1240

Fo

r Ser

rato

spicul

um

Fen

ben

daz

ole

Fin

ch10

-25

PO

QD

E15

72

Fen

ben

daz

ole

Gro

use

0.5-

0.7

Fee

dQ

DC

704

Fo

r T

rich

ostr

ongy

lus

Fen

ben

daz

ole

Gull

50P

OQ

DE

1357

Fo

r ca

pill

aria

sis

Fen

ben

daz

ole

Gull

25P

Oq2w

E13

57F

or

asca

ridia

sis

Fen

ben

daz

ole

Ost

rich

15P

ON

LB

524

Wit

h o

r w

ith

out

reso

ran

tel

Fen

ben

daz

ole

Ost

rich

30P

ON

LB

526

Add r

eso

ran

tel

Fen

ben

daz

ole

Ost

rich

15P

ON

LG

481

Fen

ben

daz

ole

Par

akee

t, A

ust

ralia

n50

Gav

age

On

ceE

1186

Fo

r ro

un

dw

orm

s

Fen

ben

daz

ole

Par

trid

ge8

Fee

dQ

DC

704

Fo

r C

apill

aria

Fen

ben

daz

ole

Par

trid

ge12

Fee

dO

nce

C70

4F

or

Syn

gam

us, H

eter

akis

, asc

arid

s

Fen

ben

daz

ole

Pen

guin

50P

ON

LE

1478

Fo

r n

emat

odes

an

d f

luke

s

Fen

ben

daz

ole

Ph

easa

nt

12P

OO

nce

C70

6

Fen

ben

daz

ole

Ph

easa

nt

8P

OQ

DC

706

Fen

ben

daz

ole

Pig

eon

16P

OO

nce

C70

4

Fen

ben

daz

ole

Pig

eon

20P

OQ

DC

706

Fo

r ga

stro

inte

stin

al r

oun

dw

orm

s

Fen

ben

daz

ole

Pig

eon

20-5

0P

OQ

DE

1240

Fo

r ca

pill

aria

sis

Fen

ben

daz

ole

Pig

eon

8P

OO

nce

E12

40A

t 8

wee

ks o

f ag

e

Fen

ben

daz

ole

Pig

eon

7.5

PO

On

ceE

1432

Fen

ben

daz

ole

Pig

eon

7.5-

20P

OO

nce

G23

2

Fen

ben

daz

ole

Pig

eon

10-1

2P

OQ

DG

260

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 35: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 275

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Fen

ben

daz

ole

Pig

eon

50P

OQ

DG

590

Fen

ben

daz

ole

Pig

eon

15P

Oq10

dG

1208

Fo

r as

cari

ds

or

Cap

illar

ia,

no

t fo

r use

duri

ng

mo

ltin

g

Fen

ben

daz

ole

Psi

ttac

ine

20-5

0P

Or2

wE

763

Fen

ben

daz

ole

Psi

ttac

ine

15P

OQ

DE

1240

May

med

icat

e fe

ed f

or

7 day

s

Fen

ben

daz

ole

Psi

ttac

ine

100

PO

q2w

E16

13F

or

asca

ridia

sis

Fen

ben

daz

ole

Psi

ttac

ine

50P

OQ

DE

1613

Fo

r ca

pill

aria

sis

Fen

ben

daz

ole

Rap

tor

10-5

0N

Lq10

dE

1132

Fo

r as

cari

dia

sis

Fen

ben

daz

ole

Rap

tor

30-5

0N

LO

nce

E11

32F

or

fluke

s

Fen

ben

daz

ole

Rap

tor

25P

OQ

DE

1159

Fo

r n

emat

odes

Fen

ben

daz

ole

Rat

ite

15P

ON

LG

418

Wit

h o

r w

ith

out

reso

ran

tel

Fen

tan

yl

Cit

rate

Avi

an0.

2SC

NL

B13

41So

me

hyp

erac

tivi

ty f

or

firs

t 15

to

30

min

ute

s

Ferr

ic S

ub

sulf

ate

Avi

anN

/A

To

pic

alP

RN

E14

73F

or

hem

orr

hag

e

Fip

ron

ilA

vian

7.5-

15N

LO

nce

G17

29F

or

larg

er b

irds

Fip

ron

ilC

anar

yN

/A

To

pic

alO

nce

G17

29Sp

ray

on

glo

ved f

inge

r an

d r

ub

un

der

win

gs

and o

n d

ors

al a

nd v

entr

al s

urf

aces

of

bo

dy

for

red m

ites

Fip

ron

ilD

ove

, Duck

7.5-

15N

LO

nce

G17

29

Fip

ron

ilR

apto

rL

igh

t Sp

ray

To

pic

alO

nce

B15

68F

or

wild

inju

red r

apto

rs w

ith

ect

op

aras

ites

Fip

ron

ilR

apto

rN

/A

To

pic

alO

nce

E13

59F

or

ecto

par

asit

es

Fla

x S

eed

Oil

Am

azo

n, Y

ello

w-n

aped

0.02

2 m

l/kg

bo

dy

wt.

Fee

dQ

DG

1033

Dilu

te 1

:4 w

ith

co

rn o

il

Fla

x Se

ed O

ilA

vian

0.1-

0.2

ml/

kgP

ON

LG

1682

Mix

1:4

wit

h c

orn

oil

pri

or

to d

osi

ng

for

ren

al

dis

ease

Flo

xacil

lin

Haw

k12

5P

OB

IDG

1110

Flo

xaci

llin

Rap

tor

250

PO

NL

E14

63F

or

bac

teri

al in

fect

ion

s

Flu

ben

dazo

leA

nse

rifo

rmes

0.24

mg/

kg f

eed

Fee

dQ

DD

1150

Co

ntr

ol n

emat

odes

Flu

ben

daz

ole

Gal

lifo

rmes

30-6

0 g/

ton

fee

dF

eed

QD

C70

4, 7

06F

or

gast

roin

test

inal

ro

un

dw

orm

s, g

apew

orm

s

and t

apew

orm

s

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 36: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I276

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Flu

co

nazo

leA

maz

on

Par

rot

20IV

-PO

q2d

D13

30F

or

keto

con

azo

le-r

esis

tan

t C

andi

da, t

issu

e-

bas

ed y

east

s, e

ye, c

ereb

ral s

pin

al, l

on

g-te

rm

Asp

ergi

llus

Flu

con

azo

leA

vian

8N

LQ

DD

1221

Fo

r cr

ypto

cocc

osi

s

Flu

con

azo

leA

vian

20P

Oq2d

D12

21F

or

can

did

iasi

s

Flu

con

azo

leA

vian

5IV

-PO

QD

D13

30

Flu

con

azo

leA

vian

20IV

-PO

q2d

D13

30A

dult

do

ase

Flu

con

azo

leA

vian

4-6

IV-P

OB

IDD

1330

Juve

nile

do

se

Flu

con

azo

leB

ird, A

quat

ic15

PO

QD

E14

78F

or

pre

ven

tio

n o

f as

per

gillo

sis,

may

als

o

neb

uliz

e

Flu

con

azo

leB

ird, A

quat

ic8

PO

BID

E15

03

Flu

con

azo

leB

ird, A

quat

ic15

PO

BID

E15

59

Flu

con

azo

leC

hic

ken

100

Gav

age

BID

G13

48F

or

mac

rorh

abdo

sis

(fo

rmer

ly m

egab

acte

ria

or

avia

n g

astr

ic y

east

), t

oxi

c to

budge

riga

rs

Flu

con

azo

leP

engu

in, A

fric

an30

PO

BID

G12

8

Flu

con

azo

leP

igeo

n5-

10P

OB

IDG

56P

rop

hyl

axis

Flu

con

azo

leP

sitt

acin

e5-

15P

OB

IDD

1446

Flu

con

azo

leP

sitt

acin

e2-

5P

OQ

DG

697

Flu

con

azo

leR

apto

r2-

5P

OQ

DE

1240

Fo

r ge

ner

aliz

ed a

sper

gillo

sis

Flu

con

azo

leR

apto

r5

PO

QD

E13

59F

or

can

did

iasi

s

Flu

con

azo

leR

apto

r2-

5P

OQ

DE

1400

Asp

ergi

llosi

s

Flu

cyto

sin

eA

vian

250

PO

BID

D12

21F

or

can

did

iasi

s

Flu

cyto

sin

eA

vian

50-1

00P

OB

IDD

674,

133

0F

or

Asp

ergi

llus

or

Can

dida

pro

ph

ylax

is, a

dd

amp

ho

teri

cin

B o

r az

ole

s fo

r th

erap

y

Flu

cyto

sin

eA

vian

40-5

0P

OT

IDE

626

Add I

V a

nd I

T a

mp

ho

teri

cin

B f

or

asp

ergi

llosi

s th

erap

y

Flu

cyto

sin

eA

vian

50-6

0P

OB

IDE

626

Asp

ergi

llus

pro

ph

ylax

is

Flu

cyto

sin

eA

vian

20-5

0P

OB

IDE

1492

Flu

cyto

sin

eB

ird, A

quat

ic50

-60

NL

BID

E15

03A

sper

gillo

sis

pro

ph

ylax

is

Flu

cyto

sin

eB

ird, A

quat

ic10

0P

OT

IDE

1503

Fo

r as

per

gillo

sis

adju

nct

th

erap

y

Flu

cyto

sin

eH

orn

bill

, Gre

at25

0P

OB

IDG

1587

Flu

cyto

sin

eP

engu

in, A

fric

an25

0P

OB

IDG

1353

May

giv

e lo

ng-

term

Flu

cyto

sin

eP

sitt

acin

e75

-120

PO

BID

D13

30F

or

Asp

ergi

llus

or

Can

dida

pro

ph

ylax

is, a

dd

amp

ho

teri

cin

B o

r az

ole

s fo

r th

erap

y

Flu

cyto

sin

eP

sitt

acin

e10

0-25

0P

OB

IDD

1330

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 37: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 277

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Flu

cyto

sin

eR

apto

r12

0P

OB

IDB

1178

Add I

T a

nd I

V a

mp

ho

teri

cin

B +

rif

amp

in

for

asp

ergi

llosi

s

Flu

cyto

sin

eR

apto

r60

PO

BID

D13

30F

or

asp

ergi

llus

or

Can

dida

pro

ph

ylax

is b

irds

> 5

00 g

, add H

1176

amp

ho

teri

cin

B o

r az

ole

s

for

ther

apy

Flu

cyto

sin

eR

atit

e80

-100

PO

BID

G13

08

Flu

cyto

sin

eSw

an50

-75

PO

BID

G86

, 697

Flu

mazen

ilA

nse

rifo

rmes

0.05

IVP

RN

D15

03, 1

533

Add a

tip

amez

ole

to

rev

erse

ket

amin

e +

med

eto

mid

ine

+ m

idaz

ola

m

Flu

maz

enil

Avi

an0.

1N

LP

RN

E14

81R

ever

se b

enzo

dia

zep

ines

Flu

maz

enil

Avi

an0.

05IV

PR

NE

1533

Flu

maz

enil

Pig

eon

0.04

IMP

RN

G16

44R

ever

se m

idaz

ola

m

Flu

nix

in M

eg

lum

ine

An

seri

form

es1

SCQ

DE

1190

Flu

nix

in M

eglu

min

eA

nse

rifo

rmes

1-10

IMN

LE

1150

Fo

r jo

int

lam

enes

s

Flu

nix

in M

eglu

min

eA

vian

1-10

IMQ

DD

1533

May

cau

se r

enal

isch

emia

at

hig

her

do

sage

s

Flu

nix

in M

eglu

min

eB

ird, A

quat

ic1-

10IM

QD

E15

03M

ay c

ause

ren

al is

chem

ia a

t h

igh

er d

osa

ges

Flu

nix

in M

eglu

min

eB

ust

ard, H

oub

ara

2N

LN

LG

1594

Swel

ling

in f

oo

t def

orm

ity

of

neo

nat

e

Flu

nix

in M

eglu

min

eD

uck

, Mal

lard

5N

LN

LA

1339

Res

idual

ph

ysio

logi

cal e

ffec

t 12

ho

urs

Flu

nix

in M

eglu

min

eD

uck

, Mal

lard

5IM

BID

A14

90F

or

fro

stb

ite

Flu

nix

in M

eglu

min

eP

igeo

n1-

10IM

-IV

QD

E14

32

Flu

nix

in M

eglu

min

eP

sitt

acin

e1-

10IM

NL

E12

40

Flu

nix

in M

eglu

min

eR

apto

r2-

10IM

QD

D14

00

Flu

oxeti

ne H

Cl

Avi

an1

NL

NL

E11

86F

or

beh

avio

ral p

rob

lem

s su

ch a

s fe

ath

er

pic

kin

g

Flu

oxe

tin

e H

Cl

Avi

an1

NL

QD

E14

77F

or

feat

her

pic

kin

g

Flu

oxe

tin

e H

Cl

Psi

ttac

ine

0.4

PO

QD

D14

46F

or

beh

avio

ral f

eath

er p

icki

ng

Fu

ralt

ad

on

e

Avi

an

0.47

mg.

/kc

al P

O

QD

E

11

80

Fura

ltad

on

e P

igeo

n

15-2

0 P

O

QD

E

56

5

Fura

ltad

on

eP

igeo

n0.

125

g/L

Dri

nk

QD

E14

92, 1

650

Fo

r sa

lmo

nel

losi

s

Fura

ltad

on

eP

igeo

n0.

4 g/

LD

rin

kQ

DE

1240

Add t

etra

cycl

ine

for

tric

ho

mo

nia

sis

and

hex

amit

iasi

s, n

ot

for

adult

s fe

edin

g yo

un

g <

10 d

ays

old

Fu

razo

lid

on

e +

Fu

ralt

ad

on

e

Pig

eon

15-2

0P

OQ

DF

1061

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 38: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I278

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Fu

rose

mid

eA

maz

on

, Yel

low

-nap

ed0.

15P

OB

IDG

1033

Furo

sem

ide

Avi

an0.

165

IMB

IDG

1309

Diu

reti

c, lo

ries

sen

siti

ve

Furo

sem

ide

Avi

an0.

1-0.

2IM

-PO

QD

-BID

E11

52F

or

diu

resi

s, r

isk

of

toxi

cosi

s es

pec

ially

in

smal

l bir

ds

Furo

sem

ide

Avi

an0.

15-2

IMQ

D-B

IDE

1650

Fo

r as

cite

s an

d e

dem

a, n

ot

for

lori

keet

s

Furo

sem

ide

Avi

an0.

15-2

IM-S

CQ

D-B

IDE

111,

147

0

Furo

sem

ide

Avi

an0.

1-0.

2IM

BID

E14

31

Furo

sem

ide

Avi

an1-

2N

LQ

D-B

IDE

1470

Fo

r co

nge

stiv

e h

eart

fai

lure

wit

h li

ver

dis

ease

Furo

sem

ide

Pig

eon

0.5-

3P

OB

ID-T

IDG

590

Furo

sem

ide

Pig

eon

2.2

IM-I

V-P

OB

IDG

590

Furo

sem

ide

Psi

ttac

ine

0.15

-2IM

-SC

QD

-BID

E12

40

Furo

sem

ide

Rap

tor

1.5

IMQ

IDE

1240

Furo

sem

ide

Rap

tor

1IM

-IV

PR

NE

1359

Furo

sem

ide

Rap

tor

1.5

IMT

ID-Q

IDE

1400

Furo

sem

ide

Rap

tor

1.5

IMP

RN

G23

4

Furo

sem

ide

Secr

etar

y B

ird

2.2

IMB

IDG

41

Fu

sid

ate

So

diu

mA

vian

2% o

intm

ent

To

pic

alB

IDE

1240

Fo

r m

ild/ea

rly

bum

ble

foo

t an

d o

ther

ski

n

lesi

on

s, m

ay p

enet

rate

inta

ct s

kin

, eff

ecti

ve

agai

nst

Sta

ph a

ureu

s

Gad

op

en

teta

te

Dim

eg

lum

ine

Avi

an0.

25 m

mo

l/kg

IVO

nce

G17

54F

or

hea

d m

agn

etic

res

on

ance

imag

ing

studie

s

Gen

tam

icin

Su

lfate

Avi

an10

ITQ

DE

704

Gen

tam

icin

Sulf

ate

Avi

an5-

10IM

BID

-TID

E70

4

Gen

tam

icin

Sulf

ate

Avi

an5

g/L

Neb

uliz

eT

IDE

741,

924

Fo

r si

nusi

tis

or

airs

accu

litis

Gen

tam

icin

Sulf

ate

Avi

an4

IMN

LE

924

Fo

r P

seud

omon

as, n

eph

roto

xic

Gen

tam

icin

Sulf

ate

Avi

an5-

10N

LQ

DE

1170

Rel

ativ

ely

ren

al t

oxi

c p

arti

cula

rly

if

deh

ydra

ted

Gen

tam

icin

Sulf

ate

Avi

an5

g/L

Flu

shB

IDE

1183

Nas

al o

r si

nus

Gen

tam

icin

Sulf

ate

Avi

an2.

5IM

BID

E14

34

Gen

tam

icin

Sulf

ate

Avi

an3-

5IM

QD

-BID

E14

92

Gen

tam

icin

Sulf

ate

Avi

an3-

5IM

QD

-BID

E16

50F

or

resi

stan

t o

rgan

ism

s

Gen

tam

icin

Sulf

ate

Bust

ard

5IM

QD

-BID

E12

40F

or

firs

t 3

day

s o

f lif

e to

pre

ven

t yo

lk s

ac

infe

ctio

ns

afte

r as

sist

ed h

atch

Gen

tam

icin

Sulf

ate

Ch

icke

n1.

5IM

TID

A71

5

Gen

tam

icin

Sulf

ate

Ch

icke

n2

IMB

IDA

1056

Fo

r ro

ost

ers

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 39: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 279

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Gen

tam

icin

Sulf

ate

Ch

icke

n10

IMB

ID-Q

IDA

1143

Gen

tam

icin

Sulf

ate

Cra

ne

5IM

TID

A45

8

Gen

tam

icin

Sulf

ate

Duck

5IM

QID

A84

7

Gen

tam

icin

Sulf

ate

Duck

, Eag

le, M

acaw

, Ow

l10

IMB

ID-Q

IDA

1143

Gen

tam

icin

Sulf

ate

Em

u5

IMT

IDA

418

Gen

tam

icin

Sulf

ate

Em

u2.

5IM

BID

A84

7

Gen

tam

icin

Sulf

ate

Haw

k, R

ed-t

aile

d2.

5IM

TID

A71

4

Gen

tam

icin

Sulf

ate

Ow

l, G

reat

-ho

rned

2.5

IMT

IDA

714

Gen

tam

icin

Sulf

ate

Ph

easa

nt

5IM

TID

A45

8

Gen

tam

icin

Sulf

ate

Pig

eon

10IM

QID

A84

7

Gen

tam

icin

Sulf

ate

Pig

eon

20IM

BID

-QID

A11

43

Gen

tam

icin

Sulf

ate

Psi

ttac

ine

10IM

BID

-TID

E56

5

Gen

tam

icin

Sulf

ate

Psi

ttac

ine

5-10

ITQ

DE

741

Add c

arb

enic

illin

fo

r p

neu

mo

nia

Gen

tam

icin

Sulf

ate

Quai

l10

IMQ

IDA

458

Gen

tam

icin

Sulf

ate

Rap

tor

2.5

IMT

IDA

565,

714

Gen

tam

icin

Sulf

ate

Rat

ite

5IM

QD

G13

08M

ay c

ause

vis

cera

l go

ut

Gen

tam

icin

Sulf

ate

Turk

ey3

IMB

IDA

880

Gen

tian

Vio

let

Mac

aw, H

yaci

nth

N/A

To

pic

alN

LE

1240

Exc

elle

nt

for

cro

p o

r sk

in f

old

can

did

iasi

s in

chic

ks

Gli

piz

ide

Co

ckat

oo

, Ro

se-b

reas

ted

0.05

g/L

Dri

nk

QD

G17

26C

rush

tab

let

into

wat

er f

or

dia

bet

es m

ellit

us

Glu

co

sam

ine S

ulf

ate

Avi

an10

dro

ps/

kgP

OT

IDE

1205

Fo

r jo

int

dis

ease

Gly

bu

rid

eC

ock

atie

l0.

0012

5-0.

0025

g/L

Dri

nk

QD

G17

20F

or

po

lyuri

a/p

oly

dip

sia

Gly

ceri

nR

apto

r<

5 m

l/kg

PO

NL

E14

63F

or

imp

acti

on

, may

giv

e cl

oac

ally

Gly

co

pyrr

ola

teP

igeo

n0.

01IM

PR

NG

1644

Add m

idaz

ola

m f

or

anes

thes

ia p

rem

ed

Go

nad

otr

op

in,

Ch

ori

on

icA

vian

500-

1000

ug/

kgIM

QD

E14

74T

reat

ch

ron

ic e

gg la

yin

g, in

ject

day

on

e, o

n

day

3 if

egg

, on

day

7 if

sec

on

d e

gg, u

se u

p t

o

3-6

w

Go

nad

otr

op

in, C

ho

rio

nic

Go

ose

0.5

mg

TD

Par

ente

ral

q3-

4dB

894

Incr

ease

sp

erm

iati

on

an

d e

arly

pub

erty

in

gan

der

s

Gri

seo

fulv

inO

stri

ch30

-50

Dri

nk

QD

G53

1, 1

308

Gri

seo

fulv

inP

igeo

n10

PO

QD

E12

40F

or

der

mat

op

hyt

osi

s

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 40: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I280

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Halo

fug

ino

n H

Br

Po

ult

ryF

eed

QD

C70

5F

or

cocc

idia

l pro

ph

ylax

is

Hal

ofu

gin

on

HB

r C

hic

ken

3

g/to

n f

oo

d

Fee

d

QD

E

56

4 Se

ven

day

sla

ugh

ter

wit

hdra

wal

Halo

peri

do

lA

vian

0.1

PO

BID

D14

75

Hal

op

erid

ol

Avi

an

0.17

D

rin

k Q

D

E

704

Bo

dy

wei

ght

less

th

an 1

kg,

gra

dual

ly in

crea

se

do

sage

to

0.9

mg/

kg

Hal

op

erid

ol

Avi

an0.

2D

rin

kQ

DE

704

Hal

op

erid

ol

Avi

an0.

4D

rin

kQ

DE

704

Mai

nte

nan

ce d

ose

Hal

op

erid

ol

Avi

an0.

4N

LN

LE

1186

Fo

r b

ehav

iora

l pro

ble

ms

such

as

feat

her

pic

kin

g

Hal

op

erid

ol

Avi

an1-

2IM

q2-

3wE

1431

Hal

op

erid

ol

Avi

an0.

2-0.

4P

OQ

DE

1431

Hal

op

erid

ol

Avi

an0.

1-0.

15N

LN

LE

1477

Fo

r se

lf-m

uti

lati

on

Hal

op

erid

ol

Avi

an0.

2P

OB

IDE

1492

Fo

r b

irds

< 1

kg

for

feat

her

pic

kin

g an

d s

elf-

muti

lati

on

, mo

st e

ffec

tive

in c

ock

ato

os

Hal

op

erid

ol

Par

rot,

Quak

er0.

08P

OB

IDE

1492

Fo

r fe

ath

er p

icki

ng

and s

elf-

muti

lati

on

Hal

op

erid

ol

Psi

ttac

ine

0.15

PO

BID

E11

1C

on

tro

l fea

ther

pic

kin

g an

d m

uti

lati

on

, bir

ds

ove

r 1

kg

Hal

op

erid

ol

Psi

ttac

ine

1-2

IMq2-

3wE

111

Co

ntr

ol f

eath

er p

icki

ng

and m

uti

lati

on

Hal

op

erid

ol

Psi

ttac

ine

0.2

PO

BID

E11

1

Hal

op

erid

ol

Psi

ttac

ine

0.4

PO

QD

E12

40F

or

feat

her

pic

kin

g

Halo

than

eA

vian

N/A

IHP

RN

E16

17In

duct

ion

, mai

nta

in w

ith

1-1

.5%

Hal

oth

ane

Pig

eon

N/A

IHP

RN

E14

321.

5-3%

mai

nte

nan

ce

Hep

ari

n S

od

ium

Avi

an40

-50

U/kg

IVO

nce

E11

51A

dd a

min

op

hyl

line,

dex

amet

has

on

e N

a

ph

osp

hat

e, f

luid

s, o

xyge

n f

or

po

lyte

traf

louro

eth

ylen

e ga

s p

ois

on

Hep

arin

So

diu

mA

vian

0.1

ml o

f 10

00U

/m

lN

ebuliz

eQ

DG

1705

Add t

o 6

.5 m

l sal

ine

Hep

arin

So

diu

mA

vian

1.0

ml o

f 10

00U

/m

l T

op

ical

QD

G17

05A

dd a

loe

vera

Hep

arin

So

diu

mSw

an55

IVO

nce

G17

07E

mac

iate

d n

ear

dea

th

Hep

asa

nA

vian

1 m

l/kg

PO

QD

G10

35F

or

liver

dis

ease

Hep

asan

Psi

ttac

ine

1 m

l/kg

PO

QD

G17

22L

iver

sup

po

rt

Heta

starc

hA

vian

10-1

5 m

l/kg

IVT

IDE

1650

Fo

r em

erge

ncy

car

e, r

educe

cry

stal

loid

flu

ids

Het

asta

rch

Avi

an10

-15

ml/

kgIV

TID

E11

51F

or

hyp

op

rote

inem

ia

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 41: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 281

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Het

asta

rch

Haw

k, R

ed-t

aile

d10

ml/

kgIV

NL

G16

26Su

pp

ort

ive

ther

apy

po

st-t

raum

a

Hexyl

Pyro

ph

eo

bo

rbid

e-a

Ho

rnb

ill, G

reat

0.3

IVq2m

G15

87F

or

squam

ous

cell

carc

ino

ma

Hyalu

ron

idase

Avi

an15

0 U

/L

flu

ids

SCN

LG

1103

Mix

wit

h f

luid

s to

aid

in a

bso

rpti

on

Hya

luro

nid

ase

Avi

an1.

5 K

IU/L

Flu

shN

LG

1719

Mix

into

nas

al a

nd s

inus

flush

es

Hya

luro

nid

ase

Avi

an1.

5 K

IU/L

Neb

uliz

eN

LG

1719

Mix

into

neb

uliz

atio

n f

luid

Hya

luro

nid

ase

Avi

an1.

5 K

IU/L

IVN

LG

1719

Fo

r eg

g yo

lk s

tro

ke

Hyd

roco

rtis

on

e S

od

ium

Su

ccin

ate

Avi

an10

IVN

LE

1470

Fo

r le

ad t

oxi

city

an

d s

ever

e in

fect

ion

wit

h

liver

dis

ease

Hyd

roxych

loro

qu

ine

Su

lfate

Pig

eon

4 ta

ble

ts/L

Dri

nk

NL

G59

0C

han

ge d

aily

Hyd

roxyzin

e H

Cl

Avi

an2

PO

TID

G13

24F

or

pru

riti

s

Hyd

roxy

zin

e H

Cl

Psi

ttac

ine

2P

OT

IDD

1446

Fo

r h

yper

sen

siti

vity

-tri

gger

ed f

eath

er p

icki

ng

Hyp

eri

cu

mA

vian

10 d

rop

s/kg

PO

TID

E12

05F

or

feat

her

pic

kin

g, a

nxi

ety

Imid

aclo

pri

dR

apto

r7

IT-I

VN

LE

1359

Fo

r b

abes

iosi

s

Imid

ocarb

HC

lR

apto

r7

NL

q3w

E13

59F

or

bab

esio

sis

Imiq

uim

od

Am

azo

n, B

lue-

fro

nte

dcr

eam

Ven

tq2-

3dB

1281

Fo

r cl

oac

al p

apill

om

ato

sis,

ap

ply

to

clo

acal

surf

ace

Ind

om

eth

acin

Avi

an0.

4IM

NL

E12

32

Indo

met

hac

inC

hic

ken

2P

ON

LA

772

Eff

ecti

ve f

or

8-10

ho

urs

Indo

met

hac

in, C

op

per

Avi

an0.

4IM

QD

E14

92F

or

acute

/ch

ron

ic in

flam

mat

ion

fro

m

trau

ma,

infe

ctio

n o

r o

rgan

dys

fun

ctio

n

Insu

lin

, N

PH

Avi

an0.

01-0

.1 U

TD

Par

ente

ral

NL

E16

50F

or

dia

bet

es m

ellit

us

in b

irds

larg

er t

han

budge

riga

r

Insu

lin, N

PH

Avi

an0.

07 U

/kg

IMQ

DG

1325

Fo

r dia

bet

es, m

on

ito

r b

loo

d g

luco

se

Insu

lin, N

PH

Budge

riga

r0.

067-

3.3

U/kg

IMB

IDE

1326

Fo

r dia

bet

es

Insu

lin, N

PH

Budge

riga

r0.

002

U T

DIM

PR

NG

58

Insu

lin, N

PH

Psi

ttac

ine

0.01

-0.1

U T

DIM

PR

NG

58, 8

8

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 42: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I282

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Insu

lin, R

egula

rA

vian

0.00

13 m

g/kc

alIM

QD

E11

80

Insu

lin, Z

inc

Susp

ensi

on

To

uca

n, T

oco

0.1-

0.5

U T

DIM

PR

NG

58

Inte

rfero

n,

Alp

ha

Avi

an15

KIU

/m

²SC

q2d

E14

70G

ive

15, 0

00 U

nit

s/m

² o

f b

ody

surf

ace

for

lym

ph

osa

rco

ma

Inte

rfer

on

, Om

ega

Avi

an10

00 K

IU T

DIM

q2d

B14

65A

dd F

10®

fo

r ci

rco

viru

s p

reve

nti

on

an

d

limit

ed e

ffec

tive

nes

s th

erap

y o

f 90

day

s

Inte

rfer

on

, Om

ega

Avi

an10

00 K

IU T

DP

aren

tera

lQ

D-B

IDG

1268

Add F

10®

fo

r ci

rco

viru

s th

erap

y

Iod

ine,

Lu

go

l's

Avi

an4

dro

ps

solu

tio

n/L

Dri

nk

NL

E11

86U

sed t

o k

eep

dri

nki

ng

wat

er u

nco

nta

min

ated

Iodin

e, L

ugo

l'sR

apto

r4

dro

ps/

L 7

% s

oln

Dri

nk

QD

E16

12

Iod

op

ho

rA

vian

N/A

To

pic

alP

RN

E11

51U

se 0

.5-1

% s

olu

tio

n f

or

wo

un

d d

ebri

dem

ent

and f

lush

ing

Iodo

ph

or

Avi

anN

/A

To

pic

alN

LE

1240

Fo

r w

oun

ds,

ap

ply

an

d w

ash

off

aft

er 3

min

ute

s, v

ery

safe

Iodo

ph

or

Rap

tor

N/A

To

pic

alN

LE

1400

Fo

r w

oun

ds,

was

h o

ff w

ith

in 5

min

ute

s

Ioh

exo

lA

vian

700-

800

IVN

LE

1182

Use

70-

80%

iodin

e co

nce

ntr

atio

n f

or

uro

grap

hy

Ioh

exo

lC

ock

atie

l24

0P

ON

LG

1623

Iop

am

ido

lA

vian

0.8-

1.2

INN

LG

1270

Use

20%

co

nce

ntr

atio

n, s

inus

con

tras

t st

udy,

flush

wit

h s

alin

e w

hen

co

mp

lete

d

Ipro

nid

azo

leA

vian

0.12

5 g/

LD

rin

kQ

DE

111,

741

Ipro

nid

azo

leP

igeo

n0.

250

g/L

Dri

nk

QD

G59

0C

han

ge d

aily

Ipro

nid

azo

leP

sitt

acin

e0.

232

g/L

PO

NL

E11

1

Iro

n D

extr

an

An

seri

form

es10

IMQ

WD

1150

Fo

r h

emo

po

iesi

s

Iro

n D

extr

anA

vian

10IM

QW

G62

Iro

n D

extr

anP

sitt

acin

e10

IMQ

W-q

10d

E12

40H

emo

po

iesi

s

Iro

n D

extr

anR

apto

r10

IMO

nce

E14

00F

or

iro

n-d

efic

ien

cy a

nem

ia

Iso

flu

ran

eA

vian

N/A

IHP

RN

E14

83M

ain

tain

1.5

-3%

Iso

nia

zid

A

maz

on

, Yel

low

-ch

eeke

d

30

NL

Q

D

G

713

Add e

tham

buto

l + r

ifam

pin

, an

tib

acte

rial

Iso

nia

zid

Avi

an

30

PO

Q

D

D

1470

A

dd e

tham

buto

l +

rif

amp

in, an

tib

acte

rial

Iso

nia

zid

Avi

an

15

PO

B

ID

E

1473 A

nti

par

asit

ic

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 43: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 283

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Iso

xu

pri

ne H

Cl

Rap

tor

5-10

PO

QD

E13

59, 1

400

Fo

r w

ing

tip

edem

a

Itra

co

nazo

leA

maz

on

Par

rot

10P

OQ

DA

16D

isso

lve

in 0

.1N

HC

l, dilu

te w

ith

ora

nge

juic

e to

tub

e fe

ed

Itra

con

azo

leA

maz

on

, Blu

e-fr

on

ted

5-10

PO

BID

A17

39C

on

tin

ue

on

ce d

aily

fo

r dura

tio

n o

f th

erap

y

Itra

con

azo

leA

nse

rifo

rmes

5-10

PO

BID

E14

73

Itra

con

azo

leA

nse

rifo

rmes

10P

OQ

DG

708

Itra

con

azo

leA

vian

10P

OQ

DA

577

Itra

con

azo

leA

vian

5-10

NL

BID

E12

39

Itra

con

azo

leB

ird, A

quat

ic20

PO

QD

E15

03F

or

asp

ergi

llosi

s p

rop

hyl

axis

Itra

con

azo

leB

ird, A

quat

ic15

PO

QD

E15

59F

or

asp

ergi

llosi

s p

rop

hyl

axis

Itra

con

azo

leC

hic

ken

10P

OB

IDA

1376

Add m

ico

naz

ole

fo

r ep

ider

mal

Asp

ergi

llus

and

Alte

rnar

ia c

ysts

aft

er s

urg

ical

rem

ova

l

Itra

con

azo

leC

ock

atie

l5

PO

QD

D13

30D

isso

lve

100

mg

cap

sule

2 m

l HC

l + 1

8 m

l

ora

nge

juic

e fo

r ca

ndid

iasi

s

Itra

con

azo

leC

ran

e10

PO

BID

B11

89A

dd e

nro

flo

xaci

n +

clo

trim

azo

le f

or

asp

ergi

llosi

s

Itra

con

azo

leC

ran

e5-

10P

OB

IDE

1361

Itra

con

azo

leE

mu

5-10

PO

QD

G16

Itra

con

azo

leF

alco

n10

-20

PO

QD

G74

6F

or

asp

ergi

llosi

s

Itra

con

azo

leG

ull

5P

OQ

DE

1357

Itra

con

azo

leP

engu

in10

NL

BID

G13

53A

sper

gillo

sis

ther

apy

lon

g-te

rm

Itra

con

azo

leP

igeo

n6

PO

BID

A70

9

Itra

con

azo

leP

igeo

n26

PO

BID

A70

9F

or

resp

irat

ory

dis

ease

, th

is d

osa

ge m

ay b

e

toxi

c

Itra

con

azo

leP

sitt

acin

e10

NL

QD

A14

24F

or

asp

ergi

llosi

s

Itra

con

azo

leP

sitt

acin

e5-

10P

OB

IDD

1446

Fo

r cu

tan

eous

cryp

toco

cco

sis

or

asp

ergi

llosi

s

Itra

con

azo

leR

apto

r5-

10N

LB

IDE

1188

Co

nti

nue

QD

fo

r 4

mo

nth

s fo

r

asym

pto

mat

ic c

ases

of

asp

ergi

llosi

s

Itra

con

azo

leR

apto

r10

PO

BID

G74

2A

dd a

mp

ho

teri

cin

B o

r en

ilco

naz

ole

+ F

10®

for

mild

asp

ergi

llosi

s

Itra

con

azo

leR

atit

e6-

10P

OQ

DG

1308

Red

uce

do

sage

if n

euro

logi

c si

gns

occ

ur

Iverm

ecti

nA

nse

rifo

rmes

0.2

PO

-SC

On

ceD

1150

, 119

0, 1

240

Co

ntr

ol n

emat

odes

an

d n

asal

or

duck

leec

hes

Iver

mec

tin

Avi

an0.

2IM

r10d

E74

1, 9

24

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 44: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I284

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Iver

mec

tin

Bir

d, A

quat

ic0.

4-0.

8N

LN

LE

1559

Fo

r p

aras

ites

Iver

mec

tin

Budge

riga

r0.

2T

op

ical

NL

E12

40In

ject

able

fo

rm m

ay b

e to

xic

Iver

mec

tin

Budge

riga

r0.

4IM

-PO

q10

dG

1309

Iver

mec

tin

Bust

ard, H

oub

ara

0.3

PO

On

ceG

932

Iver

mec

tin

Can

ary

0.2

PO

QW

G86

1F

or

air

sac

mit

es a

nd s

caly

leg

mit

es

Iver

mec

tin

Cra

ne

0.2

IM-P

Oq2w

E62

9N

emat

odes

an

d m

ites

Iver

mec

tin

Em

u0.

2SC

NL

G13

08E

ffec

tive

aga

inst

ch

andle

rello

sis

Iver

mec

tin

Fal

con

2-3

IMO

nce

B14

27F

or

serr

ato

s pic

ulia

sis

Iver

mec

tin

Fal

con

1SC

On

ceB

1585

Fo

r ca

pill

aria

sis

Iver

mec

tin

Pas

seri

ne

0.2-

0.4

PO

-To

pic

alQ

WE

1438

Fo

r m

ites

Iver

mec

tin

Pen

guin

0.4-

1P

ON

LE

1478

Fo

r n

emat

odes

Iver

mec

tin

Pig

eon

0.3

SCN

LG

57

Iver

mec

tin

Pig

eon

0.2

PO

NL

G23

2

Iver

mec

tin

Pig

eon

0.5-

1P

aren

tera

l-

PO

NL

G26

0

Iver

mec

tin

Psi

ttac

ine

0.2

IM-P

O-S

Cq2-

4wD

1446

Iver

mec

tin

Rap

tor

0.4

SCN

LG

57

Iver

mec

tin

Rap

tor

0.2

SCO

nce

G23

4

Iver

mec

tin

Rap

tor

0.2

IMN

LG

1409

Fo

r ca

pill

aria

sis

Iver

mec

tin

Rat

ite

0.2

SCN

LG

1308

Iver

mec

tin

Sto

rk, S

addle

-bill

ed0.

2P

OQ

DG

1645

Fo

r m

icro

fila

ria

Kan

am

ycin

Su

lfate

An

seri

form

es20

-40

IMB

IDG

739

Fo

r la

rge

wat

erfo

wl

Kan

amyc

in S

ulf

ate

Avi

an10

-20

IMB

IDE

565

Kan

amyc

in S

ulf

ate

Rat

ite

20-4

0IM

BID

G73

9

Kao

lin

+ P

ecti

nP

sitt

acin

e2

ml/

kgP

OB

ID-Q

IDG

632

Neo

nat

e do

sage

Kao

lin +

Pec

tin

Rap

tor

67 d

rop

s/kg

PO

TID

E16

12F

or

dia

rrh

ea

Keta

min

e H

Cl

Am

azo

n P

arro

t10

-20

IMP

RN

E24

3A

dd x

ylaz

ine

Ket

amin

e H

Cl

An

seri

form

es25

NL

PR

ND

1403

Add d

iaze

pam

, sup

ple

men

t at

15

mg/

kg

PR

N

Ket

amin

e H

Cl

An

seri

form

es10

IVP

RN

D15

03A

dd m

edet

om

idin

e +

mid

azo

lam

,

atip

amez

ole

+ f

lum

azen

il re

vers

es, g

oo

d

anes

thes

ia 3

0 m

inute

s

Ket

amin

e H

Cl

Avi

an5-

25N

LP

RN

C13

92

Ket

amin

e H

Cl

Avi

an10

-30

IMP

RN

E24

3A

dd d

iaze

pam

, hig

her

do

sage

fo

r sm

alle

r b

ird

Ket

amin

e H

Cl

Avi

an20

IMP

RN

E70

4A

dd m

idaz

ola

m

Ket

amin

e H

Cl

Avi

an5-

10IM

PR

NE

704

Add m

edet

om

idin

e

Ket

amin

e H

Cl

Avi

an10

-25

IMP

RN

G53

Add m

idaz

ola

m

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 45: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 285

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Ket

amin

e H

Cl

Avi

an10

-50

IMP

RN

G53

Add d

iaze

pam

Ket

amin

e H

Cl

Bir

d, A

quat

ic3-

8IM

PR

NE

1503

Add m

edet

om

idin

eK

etam

ine

HC

lB

ird, A

quat

ic2.

5-5

IVP

RN

E15

03A

dd x

ylaz

ine

Ket

amin

e H

Cl

Can

ary

100-

200

IMP

RN

G13

28

Ket

amin

e H

Cl

Cas

sow

ary

2.2

IVP

RN

E15

33A

dd x

ylaz

ine

Ket

amin

e H

Cl

Ch

icke

n20

-100

IMP

RN

G13

28

Ket

amin

e H

Cl

Ch

icke

n4-

5P

aren

tera

lP

RN

G17

18A

dd b

uto

rph

ano

l + m

edet

om

idin

e,

pre

anes

thet

ic f

or

iso

flura

ne

Ket

amin

e H

Cl

Co

ckat

iel

25IM

PR

NE

243

Add x

ylaz

ine

Ket

amin

e H

Cl

Co

ckat

oo

, Pal

m5

IM-S

CP

RN

E92

4Se

dat

ive

Ket

amin

e H

Cl

Duck

, Mal

lard

8.8

IMP

RN

B76

4A

dd m

edet

om

idin

e +

mid

azo

lam

, 33%

mo

rtal

ity

Ket

amin

e H

Cl

Duck

, Pek

in20

IVO

nce

B71

8

Ket

amin

e H

Cl

Em

u3

NL

PR

NC

1392

Tra

nquili

zati

on

Ket

amin

e H

Cl

Em

u2.

2IV

PR

NE

1533

Add x

ylaz

ine

Ket

amin

e H

Cl

Fal

con

, Per

egri

ne

30IV

PR

ND

1401

Add d

iaze

pam

, sup

ple

men

t at

5 m

g/kg

IV

PR

N

Ket

amin

e H

Cl

Fin

ch10

0-20

0IM

PR

NG

1328

Ket

amin

e H

Cl

Gal

lifo

rmes

3P

aren

tera

lP

RN

G17

18A

dd b

uto

rph

ano

l + m

edet

om

idin

e,

pre

anes

thet

ic f

or

iso

flura

ne

Ket

amin

e H

Cl

Go

ose

5-10

IM-I

VP

RN

B15

77A

dd m

edet

om

idin

e

Ket

amin

e H

Cl

Go

ose

20-5

0IM

PR

NG

1328

Ket

amin

e H

Cl

Guin

ea F

ow

l25

IMP

RN

B55

3A

dd x

ylaz

ine

Ket

amin

e H

Cl

Haw

k25

-30

IMP

RN

E24

3A

dd x

ylaz

ine

Ket

amin

e H

Cl

Haw

k4-

5P

aren

tera

lP

RN

G17

18A

dd b

uto

rph

ano

l + m

edet

om

idin

e,

pre

anes

thet

ic f

or

iso

flura

ne,

imp

rove

s qual

ity

of

anes

thes

ia

Ket

amin

e H

Cl

Haw

k, B

road

-win

ged

30-4

0IV

PR

NB

1092

Co

mb

ine

wit

h d

iaze

pam

Ket

amin

e H

Cl

Her

on

20N

LP

RN

G13

56

Ket

amin

e H

Cl

Ost

rich

5IV

PR

NB

555

Add x

ylaz

ine

+ a

lph

axal

on

e/al

ph

ado

lon

e

Ket

amin

e H

Cl

Ost

rich

2IM

PR

NB

1628

Add m

edet

om

idin

e

Ket

amin

e H

Cl

Ow

l10

IM-S

CP

RN

E92

4Se

dat

ive

Ket

amin

e H

Cl

Pel

ican

7IM

PR

NG

595

Ket

amin

e H

Cl

Pig

eon

20IM

PR

NB

779

Fo

llow

wit

h p

rop

ofo

l

Ket

amin

e H

Cl

Pig

eon

5IM

PR

NB

1588

Add m

edet

om

idin

e, u

sual

ly m

oder

ate

to

hea

vy s

edat

ion

Ket

amin

e H

Cl

Po

ult

ry50

IMP

RN

E4

Ket

amin

e H

Cl

Po

ult

ry30

IM-S

CP

RN

E92

4Se

dat

ive

Ket

amin

e H

Cl

Psi

ttac

ine

3-7

IMP

RN

B15

77A

dd m

edet

om

idin

e

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 46: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I286

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Ket

amin

e H

Cl

Psi

ttac

ine

2-5

IVP

RN

B15

77A

dd m

edet

om

idin

e

Ket

amin

e H

Cl

Psi

ttac

ine

10N

LP

RN

D14

01A

dd d

iaze

pam

, sup

ple

men

t at

5 m

g/kg

PR

N

Ket

amin

e H

Cl

Psi

ttac

ine

3-7

IMP

RN

E64

9A

dd m

edet

om

idin

e

Ket

amin

e H

Cl

Psi

ttac

ine

2.5-

7IV

PR

NE

649

Add m

edet

om

idin

e

Ket

amin

e H

Cl

Psi

ttac

ine

20IM

-SC

PR

NE

924

Sedat

ive

Ket

amin

e H

Cl

Rap

tor

25-3

5IM

PR

NB

1176

Fo

r la

par

osc

op

y

Ket

amin

e H

Cl

Rap

tor

2-4

IVP

RN

B15

77A

dd m

edet

om

idin

e

Ket

amin

e H

Cl

Rap

tor

3-5

IMP

RN

B15

77A

dd m

edet

om

idin

e

Ket

amin

e H

Cl

Rat

ite

3-7

IMP

RN

E4

Add m

edet

om

idin

e

Ket

amin

e H

Cl

Rat

ite

2-4

IVP

RN

E24

3P

roce

ed w

ith

xyl

azin

e

Ket

amin

e H

Cl

Rat

ite

3-20

NL

PR

NE

1386

May

add d

iaze

pam

or

xyla

zin

e if

des

ired

Ket

amin

e H

Cl

Rh

ea6.

6IM

PR

NG

1628

Add b

uto

rph

ano

l + m

edet

om

idin

e

Ket

amin

e H

Cl

Spo

on

bill

20N

LP

RN

G13

56

Ket

amin

e H

Cl

Sto

rk20

NL

PR

NG

1356

Ket

amin

e H

Cl

Swan

4IV

PR

NG

1291

Add m

edet

om

idin

e, g

as a

nes

thes

ia p

rem

ed

Ket

amin

e H

Cl

Swan

, Mute

12.5

IVP

RN

E11

90A

dd x

ylaz

ine

Ket

amin

e H

Cl

Vult

ure

10IM

PR

NB

568

Add x

ylaz

ine

Keto

co

nazo

leA

maz

on

Par

rot

30P

OB

IDB

68

Ket

oco

naz

ole

Am

azo

n, Y

ello

w-n

aped

12.5

PO

BID

G74

0

Ket

oco

naz

ole

Avi

an10

-30

PO

BID

D13

30D

isso

lve

50 m

g ta

ble

t 0.

2 m

l HC

l + 0

.8 m

l

wat

er, m

ix w

ith

aci

d ju

ice,

lact

ulo

se,

met

hyl

cellu

lose

Ket

oco

naz

ole

Avi

an10

-30

PO

BID

D17

43F

or

syst

emic

yea

st

Ket

oco

naz

ole

Bir

d, A

quat

ic25

PO

BID

E15

03F

or

can

did

iasi

s an

d a

sper

gillo

sis

ther

apy

no

t

resp

on

din

g to

nys

tati

n

Ket

oco

naz

ole

Can

ary

0.2

g/kg

so

ft f

oo

dF

eed

QD

D13

30

Ket

oco

naz

ole

Can

ary

0.2

g/L

Dri

nk

QD

E69

5

Ket

oco

naz

ole

Ost

rich

10P

OQ

DG

401

Ket

oco

naz

ole

Pas

seri

ne,

Sm

all

1 g/

LD

rin

kN

LE

1187

Ket

oco

naz

ole

Pas

seri

ne,

Sm

all

0.2

g/kg

fo

od

Fee

dO

nce

E11

87

Ket

oco

naz

ole

Pig

eon

30P

OB

IDA

68

Ket

oco

naz

ole

Pig

eon

3P

OQ

DE

704

Tab

les

crush

ed a

nd w

ater

susp

ensi

on

Ket

oco

naz

ole

Pig

eon

3G

avag

eQ

DE

1240

Fo

r re

sist

ant

can

did

iasi

s, M

ucor

an

d

Pen

icill

ium

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 47: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 287

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Ket

oco

naz

ole

Psi

ttac

ine

25P

OB

IDE

763

Fo

r ca

ndid

iasi

s o

r ad

jun

ct f

or

asp

ergi

llosi

s

ther

apy,

dis

guis

e ta

ste

in f

oo

d

Ket

oco

naz

ole

Psi

ttac

ine

10P

OB

IDE

1240

Fo

r re

sist

ant

can

did

iasi

s, M

ucor

an

d

Pen

icill

ium

Ket

oco

naz

ole

Rap

tor

15P

OB

IDE

1132

Ket

oco

naz

ole

Rap

tor

25IM

BID

E12

40F

or

resi

stan

t ca

ndid

iasi

s, M

ucor

an

d

Pen

icill

ium

Ket

oco

naz

ole

R

apto

r 60

P

O

BID

E

12

40

"

Ket

oco

naz

ole

Rap

tor

25P

OB

IDE

1359

Ket

oco

naz

ole

Rat

ite

5-10

PO

QD

G13

09

Ket

oco

naz

ole

Swan

12.5

PO

BID

D13

30D

isso

lve

50 m

g ta

ble

t 0.

2 m

l HC

l + 0

.8 m

l

wat

er, m

ix w

ith

aci

d ju

ice,

lact

ulo

se,

met

hyl

cellu

lose

Keto

pro

fen

An

seri

form

es1

IMQ

DD

1150

Fo

r p

ain

rel

ief

or

arth

riti

s

Ket

op

rofe

nA

vian

2IM

NL

D12

40, 1

533

Ket

op

rofe

nA

vian

1-4

IMN

LE

1167

Ket

op

rofe

nD

uck

5IM

NL

B13

39E

ffec

tive

30

to 7

0 m

inute

s, g

iven

duri

ng

iso

flura

ne

anes

thes

ia

Ket

op

rofe

nP

igeo

n1

mg

TD

IM-S

CQ

D-B

IDE

1240

Pai

n r

elie

f, a

rth

riti

s, a

nti

infl

amm

ato

ry

Ket

op

rofe

n

Psi

ttac

ine

2 IM

N

L

E

1240

"

Ket

op

rofe

nQ

uai

l2

PO

NL

B16

74

Lactu

lose

Am

azo

n P

arro

t0.

.07

g T

DP

OB

ID-T

IDG

1309

Fo

r h

epat

ic e

nce

ph

alo

pat

hy

Lac

tulo

seA

vian

0.3

ml/

kgP

ON

LE

1492

Fo

r liv

er d

isea

se

Lac

tulo

seP

sitt

acin

e20

0P

OB

ID-T

IDG

632

Neo

nat

e do

sage

Lasa

locid

Ch

icke

n75

Fee

dQ

DB

958

Fo

r co

ccid

ial p

rop

hyl

axis

Las

alo

cid

Gal

lifo

rmes

90-1

20 g

/to

nF

eed

QD

C70

5F

or

cocc

idia

l pro

ph

ylax

is

Leu

pro

lid

e A

ceta

teA

maz

on

, Yel

low

-nap

ed0.

75-1

Par

ente

ral

q2-

3wG

1033

Dep

ot

form

ula

tio

n

Leu

pro

lide

Ace

tate

Avi

an0.

1IM

NL

D14

75F

or

feat

her

pic

kin

g tr

igge

rin

g b

y ex

cess

ive

beh

avio

r

Leu

pro

lide

Ace

tate

Avi

an0.

5-1

IMq2w

E11

51A

fter

egg

bin

din

g

Leu

pro

lide

Ace

tate

Avi

an0.

1-0.

14P

aren

tera

lN

LE

1474

Tre

at c

hro

nic

egg

layi

ng

Leu

pro

lide

Ace

tate

Avi

an0.

052-

0.15

6IM

NL

E15

70U

se 3

0-day

dep

ot

form

ula

tio

n f

or

egg

chro

nic

egg

layi

ng

Leu

pro

lide

Ace

tate

Avi

an0.

75IM

q2w

G99

4F

or

bir

ds

300

g o

r le

ss

Leu

pro

lide

Ace

tate

Avi

an0.

5IM

q2w

G99

4F

or

bir

ds

mo

re t

han

300

g

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 48: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I288

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Leu

pro

lide

Ace

tate

Avi

an0.

75IM

q2w

G12

78In

duce

mo

lt

Leu

pro

lide

Ace

tate

Psi

ttac

ine

0.1

IMQ

DD

1446

Fo

r se

xual

ly-t

rigg

ered

fea

ther

pic

kin

g

Leu

pro

lide

Ace

tate

Rap

tor

0.25

IMq2-

3wE

1359

Fo

r cy

stic

ova

ries

Levam

iso

le H

Cl

An

seri

form

es25

-50

SCO

nce

D11

50, 1

190

Co

ntr

ol n

emat

odes

Lev

amis

ole

HC

lA

vian

2P

OQ

DD

1470

Fo

r liv

er p

aras

itic

dis

ease

Lev

amis

ole

HC

lA

vian

2IM

-SC

q2w

E11

1

Lev

amis

ole

HC

lA

vian

10-2

0P

Oq2w

E70

4

Lev

amis

ole

HC

lA

vian

8IM

-SC

r10d

E74

1N

ot

for

deb

ilita

ted b

irds

or

lori

es, u

se

13.6

5% in

ject

able

Lev

amis

ole

HC

lA

vian

10-2

0P

O-S

Cq2w

E14

34

Lev

amis

ole

HC

lA

vian

5IM

-SC

q2w

E14

73

Lev

amis

ole

HC

lA

vian

0.8

g/L

Dri

nk

QD

E14

79F

or

roun

dw

orm

s, c

ecal

wo

rms

and h

air

wo

rms

Lev

amis

ole

HC

lA

vian

40-5

0P

ON

LE

1492

Fo

r m

ost

wo

rms

Lev

amis

ole

HC

lC

ran

e25

PO

q2w

E13

61C

hic

k do

sage

fo

r in

test

inal

str

on

gyle

s, a

cari

ds

and c

apill

arid

s

Lev

amis

ole

HC

lC

ran

e40

PO

q2w

E13

61F

or

inte

stin

al s

tro

ngy

les,

asc

arid

s an

d

cap

illar

ids

Lev

amis

ole

HC

lF

inch

40-5

0P

ON

LE

1650

Fo

r m

ost

wo

rms

exce

pt

tap

ewo

rm,

par

ticu

larl

y ef

fect

ive

on

acu

aria

in A

ust

ralia

n

fin

ch

Lev

amis

ole

HC

lG

allif

orm

es40

PO

On

ceE

1503

Lev

amis

ole

HC

lG

allif

orm

es40

PO

On

ceE

1526

Lev

amis

ole

HC

lM

agp

ie30

SCN

LG

1609

Lev

amis

ole

HC

lO

stri

ch30

PO

NL

B52

6A

dd r

eso

ran

tel

Lev

amis

ole

HC

lP

arak

eet,

Aust

ralia

n15

Gav

age

q10

dG

1309

Fo

r in

test

inal

nem

ato

des

, use

inje

ctab

le

Lev

amis

ole

HC

lP

hea

san

t25

SCN

LG

678

His

tom

on

iasi

s th

erap

y

Lev

amis

ole

HC

lP

igeo

n15

IMQ

DE

704

Lev

amis

ole

HC

lP

igeo

n0.

18 g

/L

Dri

nk

QD

E70

4

Lev

amis

ole

HC

lP

igeo

n40

PO

On

ceE

1503

Lev

amis

ole

HC

lP

igeo

n40

PO

On

ceE

1526

Lev

amis

ole

HC

lP

igeo

n10

-20

PO

On

ceG

232

Rep

eat

in 2

wee

ks if

nee

ded

Lev

amis

ole

HC

lP

igeo

n40

PO

On

ceG

260

Lev

amis

ole

HC

lP

oult

ry18

-36

PO

On

ceG

1332

Lev

amis

ole

HC

lP

oult

ry1.

25-2

.5P

O-S

CN

LE

111

Lev

amis

ole

HC

lP

sitt

acin

e20

IMr2

wE

763

Em

esis

co

mm

on

Lev

amis

ole

HC

lP

sitt

acin

e20

-50

PO

QD

E12

40L

oft

tre

atm

ent

for

cap

illar

iasi

s an

d a

scar

iasi

s,

follo

w u

p w

ith

par

ente

ral t

her

apy

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 49: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 289

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Lev

amis

ole

HC

lP

sitt

acin

e2-

5IM

-SC

q10

dE

1240

Imm

un

ost

imula

nt,

low

th

erap

euti

c in

dex

Lev

amis

ole

HC

lQ

uai

l25

SCN

LG

678

His

tom

on

iasi

s th

erap

y

Lev

amis

ole

HC

lQ

uai

l20

SCN

LG

678

An

thel

min

tic

Lev

amis

ole

HC

lR

apto

r10

-20

PO

-SC

QD

E14

00N

arro

w t

her

apeu

tic

mar

gin

Lev

amis

ole

HC

lR

apto

r15

PO

-SC

NL

E14

63A

nth

elm

inti

c

Lev

amis

ole

HC

lR

apto

r2

SCq4-

6dD

1612

Imm

un

e st

imula

nt

Lev

amis

ole

HC

lR

atit

e30

IM-P

OQ

MG

1308

Beg

in a

t 1

mo

nth

of

age,

juve

nile

do

se f

or

Lib

yast

rong

ylus

dou

glas

si

Lev

amis

ole

HC

lR

atit

e30

IM-P

Oq3m

G13

08A

dult

do

se f

or

Lib

yast

rong

ylus

dou

glas

si

Levo

thyro

xin

e S

od

ium

Avi

an20

ug/

kgP

OQ

D-B

IDE

111

Lev

oth

yro

xin

e So

diu

mA

vian

1IM

-PO

NL

E92

4F

or

seve

re f

eath

er d

iso

rder

s an

d li

po

mas

Lev

oth

yro

xin

e So

diu

mA

vian

20-1

00 u

g/kg

PO

BID

E14

31M

on

ito

r le

vels

to

avo

id t

hyr

oto

xico

sis

Lev

oth

yro

xin

e So

diu

mA

vian

20 u

g/kg

PO

QD

-BID

E14

73

Lev

oth

yro

xin

e So

diu

mA

vian

0.00

08-0

.002

5 g/

LD

rin

kQ

DE

1492

Fo

r go

iter

an

d h

ypo

thyr

oid

ism

Lev

oth

yro

xin

e So

diu

mA

vian

0.02

-0.0

4P

OQ

DG

58

Lev

oth

yro

xin

e So

diu

mA

vian

0.02

PO

QD

-BID

G88

Lev

oth

yro

xin

e So

diu

mB

udge

riga

r0.

004-

0.00

8 g/

LD

rin

kQ

DD

1446

Fo

r lip

om

ato

us

gro

wth

an

d x

anth

om

as

Lev

oth

yro

xin

e So

diu

mB

udge

riga

r0.

003

g/L

Dri

nk

QD

G13

09F

or

hyp

oth

yro

idis

m, s

tir

wat

er a

nd o

ffer

fo

r

15 m

inute

s, r

epea

t dai

ly

Lev

oth

yro

xin

e So

diu

mP

sitt

acin

e0.

020-

0.1

PO

BID

E12

40F

or

hyp

oth

yro

idis

m

Lev

oth

yro

xin

e So

diu

mR

apto

r1

PO

QD

E11

60T

o in

duce

mo

ltin

g

Lid

ocain

eA

vian

2-3

SCN

LB

1346

Lo

cal i

nfi

ltra

tio

n

Lid

oca

ine

Rap

tor

2SC

NL

E14

00D

ilute

to

0.4

%, i

nfu

se lo

cally

, use

wit

h

cauti

on

in s

mal

l bir

ds

Lid

oca

ine

Rap

tor

10SC

NL

E14

63D

ilute

to

0.2

% f

or

larg

e b

ird lo

cal a

nal

gesi

a

Lin

co

mycin

HC

lA

maz

on

Par

rot

75P

OB

IDE

111,

143

1

Lin

com

ycin

HC

lA

vian

50P

OB

IDE

1234

Fo

r b

um

ble

foo

t

Lin

com

ycin

HC

lA

vian

0.2

g/L

Dri

nk

QD

E14

31F

or

infe

cted

fo

ot

lesi

on

s

Lin

com

ycin

HC

lA

vian

100

IMB

IDE

1431

Fo

r in

fect

ed f

oo

t le

sio

ns

Lin

com

ycin

HC

lH

awk

50P

OB

IDG

1110

Th

erap

y p

rio

r to

ten

do

n s

urg

ical

rep

air

Lin

com

ycin

HC

lP

igeo

n25

-50

IMN

LG

260

Lin

com

ycin

HC

lP

igeo

n35

-50

PO

QD

G59

0

Lin

com

ycin

HC

lP

oult

ry2.

2 m

g/kg

fo

od

Fee

dQ

DC

564

Lin

com

ycin

HC

lP

oult

ry0.

017

g/L

Dri

nk

QD

C56

4

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 50: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I290

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Lin

com

ycin

HC

lP

sitt

acin

e10

0IM

BID

E12

40F

or

Gra

m p

osi

tive

bum

ble

foo

t, d

erm

atit

is

and m

yco

pla

smal

res

pir

ato

ry in

fect

ion

.

Lin

com

ycin

HC

lR

apto

r11

0P

OQ

DE

741

Fo

r sk

in d

isea

se

Lin

co

mycin

HC

l +

Sp

ecti

no

mycin

HC

l

Avi

an50

PO

QD

E56

5

Lin

com

ycin

HC

l +

Spec

tin

om

ycin

HC

l

Ch

icke

n50

PO

QD

B10

65

Lin

com

ycin

HC

l +

Spec

tin

om

ycin

HC

l

Fal

con

30IM

TID

E10

27B

road

sp

ectr

um

fo

r m

yco

pla

sma

and

salm

on

ella

Lin

com

ycin

HC

l +

Spec

tin

om

ycin

HC

l

Pig

eon

50P

OQ

DF

1061

Lit

hiu

m C

arb

on

ate

Avi

an6-

25N

LB

IDE

1477

Fo

r av

ian

beh

avio

r p

rob

lem

s, m

oo

d s

tab

ilize

r

and a

nti

psy

cho

tic,

no

lon

ger

use

d in

bir

ds

LL

-E19

020

Po

ult

ry0.

01-5

0F

eed

QD

G56

4Im

pro

ves

feed

eff

icie

ncy

Mad

ura

mic

inA

vian

7.5

PO

QD

E16

50F

or

Pla

smod

ium

Mad

ura

mic

inC

hic

ken

5F

eed

QD

B95

8F

or

cocc

idia

l pro

ph

ylax

is

Mag

nesi

um

Su

lfate

An

seri

form

es50

0-10

00P

OQ

DE

1240

Incr

ease

gut

mo

tilit

y an

d a

id p

assa

ge o

f le

ad

Mag

nes

ium

Sulf

ate

Bir

d, A

quat

ic50

0-10

00P

ON

LE

1503

Pre

cip

itat

es le

ad a

nd c

ath

arti

c

Mag

nes

ium

Sulf

ate

Budge

riga

r 53

IM

P

RN

B

10

84

Add c

hlo

ral h

ydra

te +

pen

tob

arb

ital

so

diu

m,

reduce

do

se 1

5 to

20%

in d

ebili

tate

d b

irds

Mag

nes

ium

Sulf

ate

Can

ary

53

IM

PR

N

B

1084

S

ee a

bo

ve

Mag

nes

ium

Sulf

ate

Ch

icke

n

53

IM

PR

N

B

1084

S

ee a

bo

ve

Mag

nes

ium

Sulf

ate

Cro

w, E

aste

rn

53

IM

PR

N

B

1084

S

ee a

bo

ve

Mag

nes

ium

Sulf

ate

Eag

le, G

old

en

40.3

IM

P

RN

B

10

86 S

ee a

bo

ve

Mag

nes

ium

Sulf

ate

Gull

(Her

rin

g, la

ugh

ing) 5

3 IM

P

RN

B

10

84 S

ee a

bo

ve

Mag

nes

ium

Sulf

ate

Haw

k, M

arsh

32

.4

IM

PR

N

B

1086

S

ee a

bo

ve

Mag

nes

ium

Sulf

ate

Ost

rich

1.25

-30

ml T

DP

ON

LG

401

Mag

nes

ium

Sulf

ate

Pig

eon

53IM

PR

NB

1084

Add c

hlo

ral h

ydra

te +

pen

tob

arb

ital

so

diu

m,

reduce

do

se 1

5 to

20%

in d

ebili

tate

d b

irds

Mag

nes

ium

Sulf

ate

Rap

tor

250-

1000

PO

QD

E14

00F

or

ora

l hea

vy m

etal

po

iso

nin

g

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 51: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 291

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Mag

nes

ium

Sulf

ate

Rap

tor

500-

1000

PO

QD

E12

40In

crea

se g

ut

mo

tilit

y an

d a

id p

assa

ge o

f le

ad

Mala

thio

nA

vian

1 g/

LT

op

ical

NL

E14

79R

emo

ve b

irds

and t

reat

en

viro

nm

ent

for

flea

,

lice,

man

ge a

nd m

ite

trea

tmen

t an

d a

id in

tic

k

con

tro

l

Mal

ath

ion

Avi

an1

g/L

Dip

NL

E14

79F

or

flea

, lic

e, m

ange

an

d m

ite

trea

tmen

t an

d

aid in

tic

k co

ntr

ol

Mal

ath

ion

Rap

tor

5% m

ixtu

reT

op

ical

q10

dG

1411

Fo

r ch

ewin

g lic

e

Man

nit

ol

Avi

an0.

5IV

QD

E11

1G

ive

slo

wly

Marb

ofl

oxacin

Buzz

ard, C

om

mo

n2

IVB

IDA

778,

142

8

Mar

bo

flo

xaci

nB

uzz

ard, C

om

mo

n10

PO

QD

A97

9

Mar

bo

flo

xaci

nC

hic

ken

2P

OQ

DA

765

Mar

bo

flo

xaci

nR

apto

r10

IM-P

OQ

DE

1433

Mar

bo

flo

xaci

nR

apto

r15

-20

IM-P

OQ

DG

1068

Fo

r si

nusi

tis

Meb

en

dazo

leA

nse

rifo

rmes

5-15

PO

QD

D1,

150,

111

Co

ntr

ol Syn

gam

us

Meb

endaz

ole

Avi

an25

PO

QD

E14

92, 1

650

Fo

r al

l in

test

inal

wo

rms

Meb

endaz

ole

Can

ary

10P

OB

IDG

57A

void

duri

ng

bre

edin

g se

aso

n

Meb

endaz

ole

Fo

wl,

Do

mes

tic

0.06

g/kg

fo

od

Fee

dQ

DE

1051

Meb

endaz

ole

Pig

eon

5-6

PO

QD

G26

0

Meb

endaz

ole

Psi

ttac

ine

25P

OB

IDE

111,

147

3

Meb

endaz

ole

Rap

tor

25P

OB

IDE

111

Meclo

fen

am

ic A

cid

Avi

an2.

2P

OQ

DD

1533

Mec

lofe

nam

ic A

cid

Avi

an2.

2P

OQ

DG

201,

132

0

Mec

lofe

nam

ic A

cid

Avi

an2.

2P

OQ

DE

1573

Mec

lofe

nam

ic A

cid

Bir

d, A

quat

ic2.

2P

OQ

DE

1503

Med

eto

mid

ine H

Cl

Am

azo

n, Y

ello

w-c

row

ned

2IM

PR

NB

1629

Sedat

ion

pro

duce

d n

ot

relia

ble

, rev

erse

wit

h

atip

amez

ole

Med

eto

mid

ine

HC

lA

nse

rifo

rmes

0.05

IVP

RN

D15

03A

dd k

etam

ine

+ m

idaz

ola

m

Med

eto

mid

ine

HC

lA

nse

rifo

rmes

0.6-

0.85

IMP

RN

E12

31A

dd k

etam

ine

Med

eto

mid

ine

HC

lA

nse

rifo

rmes

0.06

Par

ente

ral

PR

NG

1718

Add b

uto

rph

ano

l + k

etam

ine,

pre

anes

thet

ic

for

iso

flura

ne

Med

eto

mid

ine

HC

lA

vian

0.1

IMN

LG

704,

132

0

Med

eto

mid

ine

HC

lB

ird, A

quat

ic0.

025-

0.07

5IV

PR

NE

1503

Add k

etam

ine,

rev

erse

wit

h a

tip

amez

ole

Med

eto

mid

ine

HC

lB

ird, A

quat

ic0.

05-0

.1IM

PR

NE

1503

Add k

etam

ine,

rev

erse

wit

h a

tip

amez

ole

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 52: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I292

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Med

eto

mid

ine

HC

lC

asso

war

y, D

oub

le-w

attl

ed0.

26-0

.31

IMP

RN

B12

29F

or

rest

rain

t o

f ca

pti

ve b

irds

Med

eto

mid

ine

HC

lC

hic

ken

0.1

IMP

RN

E15

73Se

dat

ion

Med

eto

mid

ine

HC

lC

hic

ken

0.06

-0.0

8P

aren

tera

lP

RN

G17

18A

dd b

uto

rph

ano

l + k

etam

ine,

pre

anes

thet

ic

for

iso

flura

ne

Med

eto

mid

ine

HC

lD

uck

, Mal

lard

0.44

IMP

RN

B76

4A

dd k

etam

ine

+ m

idaz

ola

m, 3

3% m

ort

alit

y

Med

eto

mid

ine

HC

lG

oo

se0.

1-0.

2IM

-IV

PR

NB

1577

Add k

etam

ine

Med

eto

mid

ine

HC

lH

awk

0.06

-0.0

8P

aren

tera

lP

RN

G17

18A

dd b

uto

rph

ano

l + k

etam

ine

Med

eto

mid

ine

HC

lO

stri

ch0.

08IM

PR

NB

1628

Add k

etam

ine

Med

eto

mid

ine

HC

lO

stri

ch0.

1IM

PR

NE

1573

Sedat

ion

Med

eto

mid

ine

HC

lP

igeo

n0.

.08

IMP

RN

B15

88A

dd k

etam

ine,

usu

ally

mo

der

ate

to h

eavy

sedat

ion

Med

eto

mid

ine

HC

lP

igeo

n0.

2IM

PR

NB

1588

Var

iab

le li

ght

sedat

ion

Med

eto

mid

ine

HC

lP

sitt

acin

e0.

075-

0.15

IMP

RN

B15

77A

dd k

etam

ine

Med

eto

mid

ine

HC

lP

sitt

acin

e0.

05-0

.1IV

PR

NB

1577

Add k

etam

ine

Med

eto

mid

ine

HC

lP

sitt

acin

e0.

06-0

.085

IMP

RN

E12

40A

dd k

etam

ine

Med

eto

mid

ine

HC

lR

apto

r0.

1-0.

3IM

NL

E14

00C

an b

e re

vers

ed, c

om

bin

ed w

ith

ket

amin

e fo

r

anes

thes

ia

Med

eto

mid

ine

HC

lR

apto

r0.

025-

0.07

5IV

PR

NB

1577

Add k

etam

ine

Med

eto

mid

ine

HC

lR

apto

r0.

05-0

.1IM

PR

NB

1577

Add k

etam

ine

Med

eto

mid

ine

HC

lR

apto

r0.

15-0

.35

IMP

RN

E12

40A

dd k

etam

ine

Med

eto

mid

ine

HC

lR

apto

r0.

2N

LP

RN

E14

33A

dd k

etam

ine,

rev

erse

wit

h a

tip

amez

ole

Med

eto

mid

ine

HC

lR

atit

e0.

05-0

.15

IMP

RN

E4

Add k

etam

ine

Med

eto

mid

ine

HC

lR

hea

0.73

IMP

RN

G16

28A

dd b

uto

rph

ano

l + k

etam

ine

Med

eto

mid

ine

HC

lSw

an0.

15IV

PR

NG

1291

Add k

etam

ine,

gas

an

esth

esia

pre

med

Med

roxyp

rog

est

ero

ne

Aceta

te

Lo

wer

do

se f

or

larg

er b

irds.

Si

de

effe

cts:

leth

argy

, in

app

etan

ce, p

oly

dip

sia,

fat

ty li

ver

Med

roxy

pro

gest

ero

ne

Ace

tate

Avi

an25

IM-S

CQ

DE

111

Fo

r 70

0 g

bir

d

Med

roxy

pro

gest

ero

ne

Ace

tate

Avi

an40

IM-S

CQ

DE

111

Fo

r 15

0 to

300

g b

ird

Med

roxy

pro

gest

ero

ne

Ace

tate

Avi

an50

IM-S

CQ

DE

111

Fo

r <

150

g b

ird

Med

roxy

pro

gest

ero

ne

Ace

tate

Avi

an30

IM-S

CQ

DE

111

Fo

r 30

0 to

700

g b

ird

Med

roxy

pro

gest

ero

ne

Ace

tate

Avi

an5-

25IM

-SC

QD

E11

1

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 53: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 293

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Med

roxy

pro

gest

ero

ne

Ace

tate

Avi

an5-

10IM

-SC

NL

E70

4F

or

per

sist

ent

egg

layi

ng

Med

roxy

pro

gest

ero

ne

Ace

tate

Avi

an2-

10P

O-S

CQ

WE

924

Rep

eat

afte

r 4

mo

nth

s fo

r o

vula

tio

n

sup

pre

ssio

n

Med

roxy

pro

gest

ero

ne

Ace

tate

Psi

ttac

ine

25-5

0IM

-SC

q4-

6wE

1240

Lo

wer

do

se f

or

larg

er b

irds.

Si

de

effe

cts:

leth

argy

, in

app

etan

ce, p

oly

dip

sia,

fat

ty li

ver

Mefl

oq

uin

e H

Cl

Pas

seri

ne

30P

OP

RN

E14

38G

ive

BID

on

day

1, g

ive

dai

ly o

n d

ays

2 an

d

3 an

d o

nce

per

wee

k

Meg

est

rol

Aceta

teA

vian

2.5

NL

QD

E14

31T

hen

co

nti

nue

q3-

4d f

or

feat

her

pic

kin

g w

ith

ho

rmo

nal

eti

olo

gy

Meg

estr

ol A

ceta

teC

ock

ato

o, R

ose

-bre

aste

d0.

2 g/

LD

rin

kN

LG

1609

Fo

r se

lf-m

uti

lati

on

Meg

estr

ol A

ceta

teC

ock

ato

o, R

ose

-bre

aste

d0.

2 g/

kg f

oo

dF

eed

On

ceG

1609

Fo

r se

lf-m

uti

lati

on

Melo

xic

am

Avi

an0.

1IM

-PO

QD

E11

67, 1

431

Mel

oxi

cam

Avi

an0.

1-0.

2IM

QD

E14

31L

on

g co

urs

e w

ell t

ole

rate

d

Mel

oxi

cam

Avi

an0.

1 -

1.0

PO

QD

G13

41

Mel

oxi

cam

Avi

an0.

1N

LQ

DG

1484

Mel

oxi

cam

Avi

an0.

1P

OQ

DG

1671

, 167

5

Mel

oxi

cam

Avi

an0.

1P

OQ

DE

1431

Lo

ng

cours

e w

ell t

ole

rate

d

Mel

oxi

cam

Cra

ne

0.5

PO

BID

G13

41

Mel

oxi

cam

Rap

tor

0.1-

0.2

IM-P

OQ

DE

1400

Fo

r ar

thri

tis

and o

ther

pai

nfu

l co

ndit

ion

s

Mel

oxi

cam

Rap

tor

0.1

IM-P

OQ

DE

1359

, 143

3

Mep

eri

din

e H

Cl

Rap

tor

3-5

NL

QID

G14

81

Mep

erid

ine

HC

lR

apto

r3-

5N

LN

LG

1483

, 148

4

Metf

orm

in (

glu

co

ph

ag

e)

Avi

an

100

mg/

L w

ater

D

rin

k Q

D

G

T. L

igh

tfo

ot,

2005 H

yper

glyc

emia

Meth

ocarb

am

ol

Avi

an50

IVN

LG

201

Meth

oh

exit

al

So

diu

mC

hic

ken

5-10

IVP

RN

G49

7

Met

ho

hex

ital

So

diu

mD

ove

5 g/

L b

ait

Fee

dO

nce

G17

63C

orn

is u

sual

bai

t

Met

ho

hex

ital

So

diu

mD

uck

5-10

IVP

RN

G49

8

Met

ho

hex

ital

So

diu

mG

oo

se5-

10IV

PR

NG

498

Met

ho

hex

ital

So

diu

mP

oult

ry4-

8IV

PR

NG

496

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 54: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I294

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Meth

op

ren

eR

apto

r0.

02 g

/L

To

pic

alN

LE

1068

Add p

erm

eth

rin

+ p

iper

on

yl b

uto

xide

for

ecto

par

asit

es

Meth

ylp

red

nis

olo

ne

Aceta

te

Avi

an0.

5-1

IA-I

MN

LD

1533

Met

hyl

pre

dn

iso

lon

e A

ceta

teB

ird, A

quat

ic0.

5-1

IA-I

MN

LE

1503

Met

hyl

pre

dn

iso

lon

e A

ceta

teR

apto

r5

IMQ

WE

1463

Meth

ylp

red

nis

olo

ne

So

diu

m S

uccin

ate

Avi

an0.

5-1

IM-I

VN

LD

1554

Fo

r sh

ock

Meto

clo

pra

mid

e H

Cl

Avi

an0.

3IM

-IV

-PO

NL

E11

1

Met

ocl

op

ram

ide

HC

lA

vian

0.5

IMB

ID-T

IDE

1151

To

imp

rove

mo

tilit

y, t

his

do

sage

no

t fo

r

mac

aws

Met

ocl

op

ram

ide

HC

lA

vian

0.5

IM-I

V-P

ON

LE

1473

Met

ocl

op

ram

ide

HC

lA

vian

0.5

Par

ente

ral

NL

E16

50In

crea

se g

astr

ic m

oti

lity

Met

ocl

op

ram

ide

HC

lH

awk,

Red

-tai

led

0.5

IMN

LG

1626

Sup

po

rtiv

e th

erap

y p

ost

-tra

um

a

Met

ocl

op

ram

ide

HC

lL

ori

keet

, Rai

nb

ow

0.5

SCB

IDG

1620

Fo

r vo

mit

ing

Met

ocl

op

ram

ide

HC

lM

acaw

0.1

IM-P

ON

LE

1151

To

imp

rove

mo

tilit

y- U

se lo

w d

ose

Met

ocl

op

ram

ide

HC

lO

stri

ch0.

1IV

NL

G12

55A

dd p

sylli

um

fo

r p

rove

ntr

icula

r o

bst

ruct

ion

Met

ocl

op

ram

ide

HC

lP

sitt

acin

e0.

5IM

-IV

-PO

TID

E12

40A

nti

emet

ic a

nd f

or

gut

stas

is

Met

ocl

op

ram

ide

HC

lP

sitt

acin

e0.

5N

LB

IDG

1263

Fo

r ile

us

Met

ocl

op

ram

ide

HC

lR

apto

r0.

5-2

IM-S

Cq4-

6hE

1359

Fo

r ga

stro

inte

stin

al s

tasi

s

Meto

mid

ate

HC

lA

vian

10IM

PR

NE

1130

Met

om

idat

e H

Cl

Duck

, Mal

lard

17P

OP

RN

B10

95

Met

om

idat

e H

Cl

Eag

le, A

fric

an H

awk

15.2

IMP

RN

G16

11

Met

om

idat

e H

Cl

Eag

le, T

awn

y9.

6IM

PR

NG

1611

Met

om

idat

e H

Cl

Haw

k, A

fric

an H

arri

er14

.4-1

6IM

PR

NG

1611

Met

om

idat

e H

Cl

Ost

rich

15-2

0IM

PR

NG

481

Wit

h o

r w

ith

out

azap

ero

ne

for

cap

tive

an

imal

Met

om

idat

e H

Cl

Ow

l, B

arn

10.2

IMP

RN

G16

11

Met

om

idat

e H

Cl

Rap

tor

10IM

PR

NE

1463

Smal

ler

do

sage

s fo

r vu

lture

s

Met

om

idat

e H

Cl

Rap

tor

5IM

PR

NE

1463

Fo

r se

dat

ion

Met

om

idat

e H

Cl

Turk

ey17

g/L

wh

ole

co

rnF

eed

On

ceE

1386

Safe

r th

an c

hlo

ralo

se

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 55: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 295

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Metr

on

idazo

leA

vian

25P

OB

IDD

1221

Fo

r cl

ost

ridio

sis

Met

ron

idaz

ole

Avi

an25

-50

PO

QD

E70

4, 9

24

Met

ron

idaz

ole

Avi

an0.

2 g/

LD

rin

kN

LE

1180

Met

ron

idaz

ole

Avi

an50

PO

NL

E14

34

Met

ron

idaz

ole

Avi

an5

IMB

IDE

1434

Met

ron

idaz

ole

Avi

an10

-30

PO

BID

E16

50F

or

anae

rob

ic in

fect

ion

s

Met

ron

idaz

ole

Avi

an10

IMQ

DE

1650

Fo

r an

aero

bic

infe

ctio

ns

Met

ron

idaz

ole

Avi

an50

PO

QD

G55

Met

ron

idaz

ole

Avi

an20

PO

-SC

QD

C70

5F

or

tric

ho

mo

nia

sis

Met

ron

idaz

ole

Avi

an10

-30

PO

BID

D14

70F

or

liver

par

asit

ic d

isea

se

Met

ron

idaz

ole

Avi

an10

IMQ

DD

1470

Fo

r liv

er p

aras

itic

dis

ease

Met

ron

idaz

ole

Can

ary

0.1

g/kg

fo

od

Fee

dO

nce

E11

87

Met

ron

idaz

ole

Ch

icke

n30

PO

BID

A79

5

Met

ron

idaz

ole

Fal

con

50P

OQ

DE

1027

Fo

r tr

ich

om

on

iasi

s

Met

ron

idaz

ole

Ost

rich

1.25

g/L

Dri

nk

QD

E62

7A

nti

his

tom

on

iasi

s

Met

ron

idaz

ole

Pas

seri

ne

0.1

g/L

Dri

nk

QD

E14

37A

dd d

rug

to f

oo

d a

t th

e sa

me

tim

e

Met

ron

idaz

ole

Pas

seri

ne

0.1

g/kg

so

ft f

oo

dF

eed

QD

E14

37A

dd d

rug

to d

rin

k at

th

e sa

me

tim

e

Met

ron

idaz

ole

Pig

eon

200

PO

QD

E70

4

Met

ron

idaz

ole

Pig

eon

200-

250

PO

QD

G26

0

Met

ron

idaz

ole

Po

ult

ry20

Dri

nk

QD

C70

5

Met

ron

idaz

ole

Po

ult

ry11

0P

OB

IDG

585

Met

ron

idaz

ole

Psi

ttac

ine

10-3

0P

OB

IDE

111,

147

3

Met

ron

idaz

ole

Psi

ttac

ine

25P

OB

IDE

763

Met

ron

idaz

ole

Rap

tor

30-5

0P

OQ

DE

1359

Fo

r tr

ich

om

on

iasi

s, m

ay in

crea

se d

osa

ge t

o

100

mg/

kg

Met

ron

idaz

ole

Rap

tor

50P

OQ

DE

1400

, 143

3F

or

tric

ho

mo

nia

sis

Met

ron

idaz

ole

Rap

tor

100

PO

NL

E14

63F

or

tric

ho

mo

nia

sis

Met

ron

idaz

ole

Rap

tor

50P

OQ

DG

61, 2

34

Met

ron

idaz

ole

Rap

tor

10-4

0P

OQ

DG

94Ju

ven

ile d

osa

ge

Met

ron

idaz

ole

Rap

tor

100

PO

QD

G10

68

Met

ron

idaz

ole

Rap

tor

30-6

5P

OQ

DG

1409

Fo

r tr

ich

om

on

iasi

s

Met

ron

idaz

ole

Rat

ite

20-2

5P

OB

IDG

1308

Fo

r an

aero

bic

infe

ctio

ns

Met

ron

idaz

ole

Sto

rk, S

addle

-bill

ed42

PO

BID

G16

45A

dd a

mik

acin

+ e

nro

flo

xaci

n

Mic

on

azo

le N

itra

teA

maz

on

, Red

Lo

red

2 m

gN

ebuliz

eQ

DG

700

Add a

cety

lcys

tein

e

Mic

on

azo

le N

itra

teA

vian

20IV

TID

D13

30

Mic

on

azo

le N

itra

teA

vian

10-2

0IM

QD

E56

5

Mic

on

azo

le N

itra

teA

vian

20IM

NL

E92

4F

or

can

did

iasi

s, A

sper

gillu

s, M

ucor

an

d

Pen

icill

ium

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 56: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I296

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Mic

on

azo

le N

itra

teA

vian

40IV

NL

E92

4F

or

can

did

iasi

s, A

sper

gillu

s, M

ucor

and

Pen

icill

ium

Mic

on

azo

le N

itra

teF

alco

ncr

eam

To

pic

alB

IDG

1589

Mic

on

azo

le N

itra

teP

sitt

acin

e20

IM-I

VQ

DE

704

Mic

on

azo

le N

itra

teR

apto

r10

IM-I

VQ

DE

704

Mid

azo

lam

HC

lA

nse

rifo

rmes

2IV

PR

ND

1503

, 153

3A

dd k

etam

ine

+ m

edet

om

idin

e

Mid

azo

lam

HC

l A

nse

rifo

rmes

1-

2 IV

P

RN

E

15

03

"

Mid

azo

lam

HC

l A

vian

1-

2 IM

-IV

N

L

E

1573

"

Mid

azo

lam

HC

lA

vian

1IM

NL

G20

1

Mid

azo

lam

HC

lA

vian

1-2

IM-I

VN

LG

1320

Use

wit

h a

n a

nal

gesi

c fo

r p

ain

co

ntr

ol

Mid

azo

lam

HC

lA

vian

4IM

PR

NE

704

Add k

etam

ine

Mid

azo

lam

HC

lA

vian

0.2

IMP

RN

E11

81, 1

231

Add k

etam

ine,

sm

oo

th in

duct

ion

an

d

reco

very

Mid

azo

lam

HC

lD

uck

, Mal

lard

4IM

On

ceG

1468

Pre

-gas

an

esth

esia

Mid

azo

lam

HC

lE

mu

0.4

IVP

RN

G41

8

Mid

azo

lam

HC

lO

stri

ch0.

15IV

PR

NG

418

Mid

azo

lam

HC

lP

hea

san

t, R

ing-

nec

ked

1IM

PR

NG

1644

An

esth

esia

pre

med

Mid

azo

lam

HC

lP

igeo

n0.

5IM

PR

NB

1588

Add m

edet

om

idin

e, u

sual

ly m

oder

ate

to

hea

vy s

edat

ion

Mid

azo

lam

HC

lP

igeo

n2

IMP

RN

G16

44A

dd g

lyco

pyr

rola

te f

or

anes

thes

ia p

rem

ed,

reve

rse

wit

h f

lum

azen

il

Mid

azo

lam

HC

lP

sitt

acin

e0.

2IM

-SC

PR

NE

1240

Use

in c

om

bin

atio

n w

ith

ket

amin

e

Mid

azo

lam

HC

lR

apto

r0.

5-1

IM-I

VT

IDE

1240

, 140

0C

on

tro

l sei

zure

s

Mid

azo

lam

HC

lSw

an0.

1-1

NL

PR

NG

1291

May

add b

uto

rph

ano

l, p

rem

ed f

or

gas

anes

thes

ia, l

ow

er d

osa

ge if

add b

uto

rph

ano

l

Mid

azo

lam

HC

l T

urk

ey

0.1-

1 N

L

PR

N

G

1291

"

Mil

bem

ycin

Oxim

eG

allif

orm

es2

PO

QM

B58

8

Milb

emyc

in O

xim

eG

allif

orm

es2

PO

NL

E14

92, 1

650

Fo

r H

eter

akis

, C

apill

aria

an

d a

scar

ids

Mil

k T

his

tle

Am

azo

n P

arro

t2

dro

ps

mix

ture

TD

PO

BID

G14

88M

ixtu

re is

5 d

rop

s ex

trac

t p

er 7

.5 m

l

lact

ulo

se, u

sefu

l fo

r tr

eati

ng

bir

ds

on

all

seed

die

t

Min

era

l O

ilA

vian

5 m

l/kg

Gav

age

On

ceE

1309

, 155

4T

o f

lush

GI

- la

xati

ve

Min

ocycli

ne H

Cl

Budge

riga

r5.

5 g/

kg s

eed

Fee

dQ

DA

731

Hulle

d m

edic

ated

mill

et,

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 57: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 297

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Min

ocy

clin

e H

Cl

Haw

k, R

ed-s

ho

uld

ered

5P

OB

IDG

1179

Add le

vam

iso

le +

Sta

phyl

ococ

cus

toxo

id f

or

bum

ble

foo

t

Mip

ora

mic

inP

oult

ry0.

1 g/

kgF

eed

QD

G56

4

Mo

nen

sin

So

diu

mC

hic

ken

0.1

g/kg

Fee

dQ

DB

869

Pre

ven

tive

fo

r co

ccid

iosi

s

Mo

nen

sin

So

diu

mC

hic

ken

100

Fee

dQ

DB

958

Fo

r co

ccid

ial p

rop

hyl

axis

Mo

nen

sin

So

diu

mC

hic

ken

100-

120

g/to

nF

eed

QD

C70

5F

or

cocc

idio

sis

Mo

nen

sin

So

diu

mC

ran

e0.

099

g/kg

fo

od

Fee

dO

nce

E11

1

Mo

nen

sin

So

diu

mG

allif

orm

es0.

099

g/kg

fo

od

Fee

dQ

DE

1473

Mo

nen

sin

So

diu

mP

igeo

n1-

1.2

g/kg

fee

dF

eed

On

ceE

1492

Fo

r co

ccid

iosi

s

Mo

nen

sin

So

diu

mP

igeo

n1-

1.2

g/kg

fo

od

Fee

dQ

DE

1650

Fo

r co

ccid

ia

Mo

nen

sin

So

diu

mT

urk

ey90

-100

g/to

nF

eed

QD

C70

5F

or

cocc

idio

sis

Mo

rph

ine S

ulf

ate

Gal

lifo

rmes

2.5-

3IM

-SC

NL

E11

1, 1

473

Mo

xid

ecti

nA

vian

0.2-

0.8

NL

On

ceD

1221

Fo

r ca

pill

aria

sis

Mo

xidec

tin

Car

din

al, R

ed-c

rest

ed0.

2P

ON

LG

1585

Fo

r ca

pill

aria

sis

Mo

xidec

tin

Fal

con

1P

OQ

WG

1068

Fo

r Ser

rato

spicul

um, C

apill

aria

, Phy

slao

pter

a an

d

Aca

ntho

ceph

alae

Mo

xidec

tin

Fin

ch2

PO

NL

E14

79F

or

lice,

mit

es a

nd n

emat

odes

Mo

xidec

tin

Pen

guin

0.2

PO

NL

E14

78F

or

nem

ato

des

Mo

xidec

tin

Pig

eon

0.25

mg

TD

PO

NL

D14

79F

or

lice,

mit

es a

nd n

emat

odes

Mo

xidec

tin

Psi

ttac

ine

0.2

Gav

age

On

ceD

1479

Fo

r lic

e, m

ites

an

d n

emat

odes

Mo

xidec

tin

Rap

tor

0.2

PO

QD

E13

59F

or

cap

illar

iasi

s

Mo

xidec

tin

Spar

row

haw

k0.

2SC

NL

G15

85F

or

nem

ato

dia

sis

Mu

llein

Avi

an10

dro

ps/

kgP

OT

IDE

1205

Res

pir

ato

ry, w

oun

d s

up

po

rt

Myco

bacte

riu

m V

accae

Vaccin

e

Cra

ne,

Wh

oo

pin

g0.

05 m

l TD

IDq2m

G20

7

Nalb

up

hin

e H

Cl

Guin

ea F

ow

l1-

2IM

q3h

G25

2

Nalo

xo

ne H

Cl

Avi

an0.

05-0

.25

IM-I

VP

RN

E15

73

Nal

oxo

ne

HC

lP

sitt

acin

e0.

05-0

.25

IM-I

VN

LG

1320

Use

slo

w I

V

Nal

oxo

ne

HC

lR

atit

e0.

05-0

.067

NL

PR

NG

418

Nalt

rexo

ne H

Cl

Avi

an1.

5D

rin

kN

LE

704

Beh

avio

r m

odif

icat

ion

, fea

ther

pic

kin

g

Nal

trex

on

e H

Cl

Ost

rich

300

mg

TD

IVP

RN

B52

1R

ever

se c

arfe

nta

nil

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 58: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I298

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Nal

trex

on

e H

Cl

Psi

ttac

ine

1.5

PO

BID

E12

40P

reve

nt

self

-muti

lati

on

Nan

dro

lon

eP

sitt

acin

e0.

4IM

-SC

q3w

E12

40F

or

chro

nic

an

d d

ebili

tati

ng

dis

ease

, may

cause

live

r dis

ease

Nan

dro

lon

e R

apto

r 0.

4 IM

-SC

q3w

E

12

40

"

Nara

sin

Ch

icke

n70

Fee

dQ

DB

958

Fo

r co

ccid

ial p

rop

hyl

axis

Nar

asin

Ch

icke

n60

-80

mg/

kg f

oo

dF

eed

QD

E56

4A

dd n

icar

baz

in, 5

-day

sla

ugh

ter

wit

hdra

wal

,

pro

ph

ylac

tic

Neo

mycin

Su

lfate

Avi

an1.

25 g

/L

Dri

nk

NL

E11

1

Neo

myc

in S

ulf

ate

Avi

an10

PO

QD

E56

5

Neo

myc

in S

ulf

ate

Avi

an20

PO

NL

E92

4G

ram

neg

ativ

e, p

oo

r ab

sorp

tio

n

Neo

myc

in S

ulf

ate

Ch

icke

n11

Dri

nk

BID

C13

07F

or

bac

teri

al e

nte

riti

s

Neo

myc

in S

ulf

ate

Ch

icke

n.0

77-.

154

g/kg

fo

od

Fee

dQ

DC

1307

Fo

r b

acte

rial

en

teri

tis

Neo

myc

in S

ulf

ate

Duck

.077

-.15

4 g/

kg f

oo

dF

eed

QD

C13

07F

or

bac

teri

al e

nte

riti

s

Neo

myc

in S

ulf

ate

Duck

11D

rin

kB

IDG

1307

Fo

r b

acte

rial

en

teri

tis

Neo

myc

in S

ulf

ate

Pas

seri

ne

0.2

g/kg

so

ft f

oo

dF

eed

QD

E14

37A

dd d

rug

to d

rin

k at

th

e sa

me

tim

e

Neo

myc

in S

ulf

ate

Pas

seri

ne

0.2

g/L

Dri

nk

QD

E14

37A

dd d

rug

to f

oo

d a

t th

e sa

me

tim

e

Neo

myc

in S

ulf

ate

Po

ult

ry0.

035-

0.08

g/L

Dri

nk

QD

C56

4P

rop

hyl

acti

c

Neo

myc

in S

ulf

ate

Po

ult

ry38

.5-1

54 m

g/kg

fo

od

Fee

dQ

DC

564

Neo

myc

in S

ulf

ate

Po

ult

ry11

PO

QD

C56

4

Neo

myc

in S

ulf

ate

Rap

tor

15P

ON

LE

1463

Fo

r b

acte

rial

infe

ctio

ns

Neto

bim

inA

vian

0.03

5-0.

08 g

/L

Dri

nk

QD

E14

92F

or

tap

ewo

rms,

asc

arid

s an

d H

eter

akis

Net

ob

imin

Bir

d, A

quat

ic0.

35 g

/L

Dri

nk

QD

E15

03

Net

ob

imin

Rap

tor

20P

OQ

DB

1568

Nic

arb

azin

Ch

icke

n20

-50

mg/

kg f

oo

dF

eed

QD

E56

4A

dd n

aras

in, 5

-day

sla

ugh

ter

wit

hdra

wal

,

pro

ph

ylac

tic

Nic

losa

mid

eA

vian

50P

Oq2w

E11

1

Nic

losa

mid

eA

vian

150-

250

PO

NL

G57

Nic

losa

mid

eA

vian

5 g/

kg f

oo

dF

eed

QD

G57

Nic

losa

mid

eC

ran

e25

0N

Lq2w

G59

6

Nic

losa

mid

eF

alco

n20

0P

OO

nce

E10

27F

or

tap

ewo

rms

Nic

losa

mid

eF

inch

500

Fee

dQ

WE

111

Nic

losa

mid

eO

stri

ch10

0P

Oq6w

G40

1

Nic

losa

mid

eO

stri

ch50

PO

NL

G48

1

Nic

losa

mid

eP

elic

an, B

row

n10

3-16

0P

OO

nce

B10

89

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 59: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 299

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Nic

losa

mid

eP

igeo

n75

PO

NL

G57

Nic

losa

mid

eR

apto

r15

6P

OO

nce

D16

12F

or

cest

odia

sis

Nic

losa

mid

eR

apto

r12

5P

ON

LE

1068

Fo

r ce

sto

des

Nif

urs

ol

Po

ult

ry77

mg/

kg f

oo

dF

eed

QD

C56

4P

rop

hyl

acti

c

Nif

urs

ol

Turk

ey75

mg/

kg f

oo

dF

eed

QD

E56

4N

utr

itio

nal

use

, 5-d

ay s

laugh

ter

wit

hdra

wal

Nif

urs

ol

Turk

ey50

g/to

nF

eed

QD

C70

5F

or

his

tom

on

iasi

s

Nit

hia

mid

eR

apto

r40

PO

NL

E14

63F

or

tric

ho

mo

nia

sis

Nit

rofu

razo

ne

Avi

an1.

25 m

l/L

Dri

nk

QD

E74

1F

or

cocc

idia

l in

fect

ion

s

Nit

rofu

razo

ne

Ch

icke

n55

mg/

kg f

oo

dF

eed

QD

E56

45-

day

sla

ugh

ter

wit

hdra

wal

, pro

ph

ylac

tic

Nit

rofu

razo

ne

Lo

rike

et

0.62

5 cc

/L

D

rin

k N

L

E

111

Do

sage

bas

ed o

n 9

.2%

po

wder

Nit

rofu

razo

ne

Po

ult

ry

55 m

g/kg

fo

od

Fee

d

QD

C

56

4

Nit

rofu

razo

ne

Psi

ttac

ine

1.25

cc/

LD

rin

kN

LE

111

Do

sage

bas

ed o

n 9

.2%

po

wder

Nit

rom

ide

Ch

icke

n25

0 m

g/kg

fo

od

Fee

dQ

DE

564

Add s

ulf

anit

ran

+ r

oxa

rso

ne,

5-d

ay s

laugh

ter

wit

hdra

wal

Nit

roxin

ilG

allif

orm

es24

Dri

nk

QD

C70

6F

or

gap

ewo

rms

No

rdih

yd

roq

uaia

reti

cA

vian

2 dro

ps/

kgP

OB

IDE

1205

Use

wit

h c

auti

on

in e

gg la

yers

or

w/ h

epat

ic

dis

ease

No

rflo

xacin

Ch

icke

n10

PO

BID

A78

9

No

rflo

xaci

nC

hic

ken

8P

OQ

DA

830

No

rflo

xaci

nC

hic

ken

20-4

0D

rin

kN

LA

840

Fo

r H

emop

hilu

s pa

raga

llina

rum

in

fect

ion

.

No

rflo

xaci

nG

oo

se10

PO

BID

A78

9

No

rflo

xaci

nO

stri

ch30

Dri

nk

QD

G56

2

No

rflo

xaci

nP

oult

ry8

PO

QD

G56

4

No

rflo

xaci

nT

urk

ey10

PO

QID

A78

9

No

rflo

xaci

nT

urk

ey10

SCQ

DA

1020

No

rtri

pty

lin

e H

Cl

Psi

ttac

ine

0.01

6 g/

LD

rin

kN

LE

111

Co

ntr

ol f

eath

er p

icki

ng

No

sih

ep

tid

eC

hic

ken

5-10

mg/

kgF

eed

QD

G56

4Im

pro

ves

feed

eff

icie

ncy

No

vo

bio

cin

So

diu

mA

nse

rifo

rmes

385

mg/

kg f

oo

dF

eed

On

ceG

597

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 60: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I300

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

No

vob

ioci

n S

odiu

mD

uck

, Pek

in0.

3 g/

kg f

oo

dF

eed

On

ceB

984

Pro

ph

ylax

is f

or

Pas

teur

ella

mul

tocida

in

duck

lings

.

Nyst

ati

nA

nse

rifo

rmes

300

KIU

/kg

PO

BID

D11

50F

or

can

did

iasi

s

Nys

tati

n

Avi

an

200

KIU

/kg

F

eed

QD

E

70

4 So

ft f

oo

d

Nys

tati

n

Avi

an

0.05

g/kg

fo

od

PO

N

L

E

924

Fo

r ca

ndid

iasi

s

Nys

tati

n

Avi

an

300

KIU

/kg

P

O

BID

E

12

21 F

or

can

did

iasis

Nys

tati

n

Avi

an

200-

300

KIU

/kg

P

O

BID

G

13

73 F

or

can

did

iasis

Nys

tati

n

Avi

an

100

KIU

/L

D

rin

k Q

D

G

1744

F

or

can

did

iasis

Nys

tati

n

Fin

ch

333

KIU

/kg

P

O

QD

E

15

72 F

or

can

did

iasis

Nys

tati

nH

um

min

gbir

d10

0 K

IU/m

lT

op

ical

q4-

6hG

599

Fo

r m

outh

lesi

on

s

Nys

tati

nH

um

min

gbir

d25

KIU

/L

Nec

tar

Dri

nk

QD

G59

9

Nys

tati

nO

stri

ch25

00 K

IU/kg

fo

od

Fee

dO

nce

G28

3

Nys

tati

nO

stri

ch12

.5 K

IU/kg

PO

QD

G40

1

Nys

tati

nO

stri

ch0.

24 g

/kg

fee

dF

eed

QD

G12

54F

or

can

did

iasi

s

Nys

tati

nO

stri

ch20

-50

KIU

/kg

PO

QD

G12

54

Nys

tati

nP

asse

rin

e10

0 K

IU/L

Dri

nk

QD

D13

30A

dd t

o f

oo

d a

lso

, up

per

GI

Can

did

iasi

s

Nys

tati

nP

igeo

n20

-100

KIU

PO

QD

E70

4

Nys

tati

nP

igeo

n10

0-15

0 K

IU/kg

PO

BID

G59

0

Nys

tati

nP

oult

ry11

0 m

g/kg

fo

od

Fee

dQ

DC

564

Hal

f do

sage

is p

rop

hyl

acti

c

Nys

tati

nP

sitt

acin

e30

0 K

IU/kg

PO

-To

pic

alB

ID-T

IDD

1330

Up

per

GI

can

did

iasi

s

Nys

tati

nP

sitt

acin

e33

3 K

IU/kg

PO

TID

E76

3F

or

can

did

iasi

s, u

se le

sser

do

sage

to

die

t fo

r

neo

nat

es o

n a

nti

bio

tic

ther

apy

Nys

tati

nR

apto

r10

0 K

IU/kg

PO

TID

D16

12

Nys

tati

nR

apto

r1

KIU

/kg

PO

BID

E11

32

Nys

tati

nR

apto

r20

KIU

/kg

PO

BID

E11

88

Nys

tati

nR

atit

e30

0 K

IU/kg

PO

NL

G41

8

Nys

tati

nR

atit

e10

0 K

IU T

DP

OT

IDG

594

Nys

tati

n

Turk

ey

0.05

5-0.1

1 g/

kg f

ood F

eed

QD

C

13

07

Ole

an

do

mycin

Ph

osp

hate

Avi

an1.

17 m

g/kc

alP

OQ

DE

1180

Ole

ando

myc

in P

ho

sph

ate

Avi

an0.

58 m

g/kc

alIM

QD

E11

80

Ole

ando

myc

in P

ho

sph

ate

Pig

eon

25IM

QD

E56

5

Ole

ando

myc

in P

ho

sph

ate

Pig

eon

50P

OQ

DE

565

Orm

eto

pri

m +

Su

lfad

imeth

oxin

e

Ch

icke

n0.

2 g/

kg f

oo

dF

eed

QD

E56

45-

day

sla

ugh

ter

wit

hdra

wal

, pro

ph

ylac

tic

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 61: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 301

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Orm

eto

pri

m +

Sulf

adim

eth

oxi

ne

Cra

ne

0.41

g/kg

fo

od

Fee

dQ

DE

1361

Fo

r co

ccid

iosi

s

Orm

eto

pri

m +

Sulf

adim

eth

oxi

ne

Duck

0.22

g/kg

Fee

dO

nce

B82

5F

or

Pas

teur

ella

mul

tocida

in d

uck

lings

Orm

eto

pri

m +

Sulf

adim

eth

oxi

ne

Duck

0.2-

0.8

g/kg

fo

od

Fee

dO

nce

B86

0F

or

riem

erel

losi

s an

d c

olib

acill

osi

s

Orm

eto

pri

m +

Sulf

adim

eth

oxi

ne

Po

ult

ry0.

3-0.

5 g/

LD

rin

kQ

DG

585

Orm

eto

pri

m +

Sulf

adim

eth

oxi

ne

Turk

ey0.

44 g

/kg

Fee

dO

nce

B84

6P

rop

hyl

axis

fo

r P

aste

urel

la m

ulto

cida

Orm

eto

pri

m +

Sulf

adim

eth

oxi

ne

Turk

ey0.

1 g/

kg f

oo

dF

eed

QD

E56

45-

day

sla

ugh

ter

wit

hdra

wal

, pro

ph

ylac

tic

Oxacil

lin

So

diu

mP

sitt

acin

e10

0P

OT

IDD

1446

Fo

r st

aph

ylo

cocc

al d

erm

atit

is

Oxfe

nd

azo

leA

vian

10N

Lq2w

D12

21F

or

cap

illar

iasi

s

Oxf

endaz

ole

Avi

an40

PO

QD

D14

70F

or

liver

par

asit

ic d

isea

se

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ole

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an4

PO

QD

D14

79F

or

mo

st in

test

inal

wo

rms

incl

udin

g

tap

ewo

rms

Oxf

endaz

ole

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an0.

1-0.

2 g/

LD

rin

kQ

DD

1479

Fo

r m

ost

inte

stin

al w

orm

s in

cludin

g

tap

ewo

rms

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ole

A

vian

10

P

O

QD

E

16

50

Fo

r m

ost

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al w

orm

s

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ole

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an0.

1-0.

2 g/

LD

rin

kQ

DE

1650

Fo

r m

ost

inte

stin

al w

orm

s

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endaz

ole

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rich

5P

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egin

at

age

4 m

on

ths,

alt

ern

ate

ther

apeu

tic

agen

t

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endaz

ole

Pig

eon

10-4

0P

OO

nce

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0

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ole

Rap

tor

10P

OQ

WG

1068

Oxyte

tracycli

ne

Am

azo

n P

arro

t22

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IMQ

D-B

IDA

266

Oxy

tetr

acyc

line

An

seri

form

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5 g/

LD

rin

kQ

DE

1240

Fo

r ch

lam

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ph

ilosi

s

Oxy

tetr

acyc

line

An

seri

form

es50

mg

TD

PO

QD

E12

40

Oxy

tetr

acyc

line

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an50

00 m

g/kg

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dQ

DE

704

Add c

itri

c ac

id, t

her

apeu

tic

do

sage

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tetr

acyc

line

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an50

-100

IMQ

DE

1431

Oxy

tetr

acyc

line

Avi

an50

IMQ

D-B

IDE

1492

Oxy

tetr

acyc

line

Avi

an10

0P

OQ

D-B

IDE

1492

Oxy

tetr

acyc

line

Bir

d, A

quat

ic10

0SC

QD

E15

03F

or

resp

irat

ory

infe

ctio

ns

Oxy

tetr

acyc

line

Budge

riga

r2

g/L

Neb

uliz

eq4-

6hA

876

Fo

r re

spir

ato

ry d

isea

se

Oxy

tetr

acyc

line

Ch

icke

n2.

5 g/

LD

rin

kN

LA

802

Add o

xyte

trac

yclin

e fe

ed a

lso

Oxy

tetr

acyc

line

Ost

rich

10IM

QD

G40

1D

oub

le d

osa

ge f

or

bir

ds

bel

ow

5 k

g

Oxy

tetr

acyc

line

Ow

l16

IMQ

DA

55

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 62: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I302

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Oxy

tetr

acyc

line

Ph

easa

nt

43IM

QD

A55

Oxy

tetr

acyc

line

Pig

eon

50IM

-SC

QD

A10

67

Oxy

tetr

acyc

line

Pig

eon

0.13

3-0.

444

g/L

Dri

nk

QD

E70

4

Oxy

tetr

acyc

line

Pig

eon

100

IMq2d

E70

4

Oxy

tetr

acyc

line

Pig

eon

20IM

q2d

E12

40A

dd t

etra

cycl

ine

for

bir

ds

ove

r 70

0 g

Oxy

tetr

acyc

line

Pig

eon

80IM

q2d

E12

40A

dd t

etra

cycl

ine

for

bir

ds

un

der

400

g

Oxy

tetr

acyc

line

Po

ult

ry0.

0265

-0.1

06 g

/L

Dri

nk

QD

C56

4

Oxy

tetr

acyc

line

Po

ult

ry6.

25-2

00 m

g T

DP

OQ

DC

564

Oxy

tetr

acyc

line

Po

ult

ry11

0-22

0 m

g/kg

fo

od

Fee

dQ

DC

564

Add n

eom

ycin

Oxy

tetr

acyc

line

Po

ult

ry0.

06-0

.25

g/L

Dri

nk

QD

C70

5

Oxy

tetr

acyc

line

Psi

ttac

ine

58IM

QD

A55

Oxy

tetr

acyc

line

Psi

ttac

ine

50IM

QD

E12

40

Oxy

tetr

acyc

line

Psi

ttac

ine

50-1

00SC

q2-

3dE

1365

Fo

r ch

lam

ydo

ph

ilosi

s

Oxy

tetr

acyc

line

Rap

tor

25-5

0IM

-PO

TD

E12

40IM

inje

ctio

n m

ay c

ause

musc

le n

ecro

sis

Oxy

tetr

acyc

line

Turk

ey2.

5 g/

LD

rin

kN

LA

802

Add o

xyte

trac

yclin

e fe

ed a

lso

Oxy

tetr

acyc

line

Turk

ey25

00 p

pm

Fee

dO

nce

A80

2A

dd o

xyte

trac

yclin

e dri

nki

ng

wat

er a

lso

Oxy

tetr

acyc

line

Turk

ey22

0 m

g/kg

fo

od

Fee

dQ

DE

564

3-day

sla

ugh

ter

wit

hdra

wal

, pro

ph

ylac

tic

Oxyte

tracycli

ne

Am

ph

ote

ric

Am

azo

n P

arro

t60

IMQ

DA

847

Oxy

tetr

acyc

line

Am

ph

ote

ric

Am

azo

n, B

lue-

fro

nte

d75

SCq3d

E70

3F

or

chla

myd

op

hilo

sis

Oxy

tetr

acyc

line

Am

ph

ote

ric

An

seri

form

es20

0IM

QD

D11

50F

or

pas

teure

llosi

s an

d o

ther

bac

teri

a

Oxy

tetr

acyc

line

Am

ph

ote

ric

Avi

an50

SCq3-

5dE

1648

Fo

r re

spir

ato

ry in

fect

ion

s, m

ay c

ause

musc

le

nec

rosi

s

Oxy

tetr

acyc

line

Am

ph

ote

ric

Bir

d, A

quat

ic50

SCq3-

5dE

1503

Fo

r re

spir

ato

ry in

fect

ion

s

Oxy

tetr

acyc

line

Am

ph

ote

ric

Co

ckat

oo

, Go

ffin

50-1

00IM

-SC

q3d

A38

0

Oxy

tetr

acyc

line

Am

ph

ote

ric

Mac

aw, B

lue

and G

old

50-7

5SC

q2-

3dE

1170

Cau

ses

irri

tati

on

at

inje

ctio

n s

ite

Oxy

tetr

acyc

line

Am

ph

ote

ric

Ost

rich

20IM

q3d

G40

1D

oub

le d

osa

ge f

or

bir

ds

bel

ow

5 k

g

Oxy

tetr

acyc

line

Am

ph

ote

ric

Psi

ttac

ine

50-1

00IM

-SC

q2-

3dE

565

Oxy

tetr

acyc

line

Am

ph

ote

ric

Rap

tor

50-2

00IM

q3-

5dE

1240

Fo

r p

aste

ure

llosi

s

Oxy

tetr

acyc

line

Am

ph

ote

ric

Turk

ey15

0SC

q3d

A72

7L

on

g-la

stin

g fo

rmula

tio

n

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 63: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 303

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Oxyto

cin

An

seri

form

es3-

5 IU

/kg

IMN

LD

1150

Egg

bin

din

g

Oxy

toci

nA

vian

0.5-

1 IU

TD

IMN

LE

924

Use

wit

h c

alci

um

an

d v

itam

in A

fo

r eg

g

exp

uls

ion

Oxy

toci

nA

vian

5 U

/kg

IV-S

CO

nce

E11

51T

o h

elp

wit

h e

gg e

xpuls

ion

, add c

alci

um

,

fluid

s an

d h

eat

Oxy

toci

nA

vian

2 IU

/kg

NL

NL

E14

31F

or

egg

bin

din

g, g

ive

calc

ium

bo

rogl

uco

nat

e

also

Oxy

toci

nO

stri

ch5

IU T

DIV

On

ceB

1257

Giv

e 2

to 4

min

ute

s b

efo

re s

emen

co

llect

ion

Paro

mo

mycin

Su

lfate

Avi

an10

0P

OB

IDE

1474

Fo

r n

eon

ate

wit

h c

ryp

tosp

ori

dio

sis

Pen

etr

an

Avi

anT

op

ical

NL

G14

86F

or

rash

es, u

lcer

atio

n, l

oca

l irr

itat

ion

, tra

um

a,

bit

es, b

urn

s, e

tc.

Pen

etra

nA

vian

2.5

ml/

L s

pra

yT

op

ical

NL

G11

03F

or

pic

kin

g o

r it

chin

g

Pen

icil

lam

ine

An

seri

form

es55

PO

BID

D11

50F

or

hea

vy m

etal

po

iso

nin

g

Pen

icill

amin

eA

vian

55P

OB

IDD

1221

Fo

r le

ad o

r zi

nc

toxi

cosi

s, m

ay u

se in

con

jun

ctio

n w

ith

edet

ate

calc

ium

dis

odiu

m

Pen

icill

amin

eA

vian

52P

OQ

DF

1236

Fo

r co

pp

er t

oxi

cosi

s

Pen

icill

amin

eA

vian

55P

OB

IDG

87R

epea

t af

ter

3 to

5 d

ays

Pen

icill

amin

eP

sitt

acin

e50

-55

PO

BID

E12

40C

hel

atio

n a

gen

t fo

r co

pp

er, z

inc,

mer

cury

and le

ad

Pen

icill

amin

eR

apto

r55

PO

BID

E12

40F

or

hea

vy m

etal

po

iso

nin

g

Pen

icil

lin

An

seri

form

es50

KIU

/kg

Par

ente

ral

NL

G59

7

Pen

icill

inP

oult

ry44

KIU

/kg

PO

QD

C56

4A

dd s

trep

tom

ycin

Pen

icill

inP

oult

ry55

-110

mg/

kg f

oo

dF

eed

QD

C56

4P

rop

hyl

acti

c

Pen

icill

inP

oult

ry37

5 K

IU/L

Dri

nk

QD

C56

4

Pen

icill

inP

oult

ry11

0 m

g/kg

fo

od

Fee

dQ

DC

564

Pen

icill

inP

oult

ry2.

65 m

g/kg

fo

od

Fee

dQ

DE

564

Add s

trep

tom

ycin

, nutr

itio

nal

use

, no

slau

ghte

r w

ith

dra

wal

Pen

icill

inR

apto

r<

100

KIU

/kg

IM-I

VN

LE

1463

Use

cry

stal

line

form

ula

tio

n f

or

bac

teri

al

infe

ctio

ns

Pen

icil

lin

G B

en

zath

ine

Rh

ea10

0 K

IU T

DSC

QD

G58

2A

dd t

ylo

sin

Pen

icill

in G

Ben

zath

ine

Turk

ey 100 IM

Q

D

A

385

Add p

enic

illin

G p

roca

ine

for

Pas

teur

ella

mul

tocida

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 64: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I304

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Pen

icil

lin

G P

ota

ssiu

mA

vian

66-1

33 K

IU/kg

IMN

LF

1209

Pen

icill

in G

Po

tass

ium

Fal

con

, Lan

ner

20 K

IU/kg

IMQ

IDB

1175

Po

st-s

urg

ical

tre

atm

ent

of

bum

ble

foo

t

Pen

icill

in G

Pro

cain

eG

allif

orm

es10

0IM

q2d

E11

1, 1

473

Pen

icill

in G

Pro

cain

e T

urk

ey

100

IM

On

ce

A

385

Lo

adin

g do

se, a

dd p

enic

illin

G w

ith

pro

cain

e

ben

zath

ine

for

Pas

teur

ella

mul

tocida

Pen

tob

arb

ital

+ C

hlo

ral

Hyd

rate

+ M

ag

nesi

um

Su

lfat

Avi

an16

0-18

0IM

PR

NF

1209

Do

sage

bas

e o

n c

om

bin

ed m

g o

f

pen

tob

arb

ital

/ch

lora

l hyd

rate

/m

agn

esiu

m

sulf

ate

Pen

tob

arb

ital

So

diu

mA

vian

5IM

PR

NE

1130

Pen

tob

arb

ital

So

diu

mA

vian

50IM

PR

NF

1209

Pen

tob

arb

ital

So

diu

mB

udge

riga

r24

IMP

RN

B10

84A

dd c

hlo

ral h

ydra

te +

mag

nes

ium

sulf

ate,

reduce

do

se 1

5 to

20%

in d

ebili

tate

d b

irds

Pen

tob

arb

ital

So

diu

m

Can

ary

24

IM

PR

N

B

1084

S

ee a

bo

ve

Pen

tob

arb

ital

So

diu

mC

hic

ken

16.2

IMP

RN

B10

80A

dd t

hio

pen

tal s

odiu

m

Pen

tob

arb

ital

So

diu

mC

ock

ato

o, M

ajo

r M

itch

ell's

100

mg

TD

IVN

LG

1590

Pen

tob

arb

ital

So

diu

mC

ow

bir

d10

0-15

0 g/

kg f

oo

dF

eed

On

ceB

1094

Pen

tob

arb

ital

So

diu

mC

ran

e, E

uro

pea

n24

IMP

RN

B10

84A

dd c

hlo

ral h

ydra

te +

mag

nes

ium

sulf

ate,

reduce

do

se 1

5 to

20%

in d

ebili

tate

d b

irds

Pen

tob

arb

ital

So

diu

mD

uck

, Mal

lard

22P

OP

RN

B10

95

Pen

tob

arb

ital

So

diu

mD

uck

, No

rth

ern

Pin

tail

390

IVO

nce

B15

93P

rece

de

wit

h k

etam

ine

by

15 m

inute

s

Pen

tob

arb

ital

So

diu

mE

agle

, Go

lden

18.2

IMP

RN

B10

86A

dd c

hlo

ral h

ydra

te +

mag

nes

ium

sulf

ate,

reduce

do

se 1

5 to

20%

in d

ebili

tate

d b

irds,

fled

glin

g

Pen

tob

arb

ital

So

diu

mE

mu

13.3

IVP

RN

G28

3P

rem

edic

ate

wit

h d

iaze

pam

Pen

tob

arb

ital

So

diu

mG

allif

orm

es50

-100

PO

PR

NE

1130

Use

tab

lets

Pen

tob

arb

ital

So

diu

mG

oo

se50

-100

PO

PR

NE

1130

Use

tab

lets

Pen

tob

arb

ital

So

diu

mG

ull,

Cal

ifo

rnia

24IM

PR

NB

1084

Add c

hlo

ral h

ydra

te +

mag

nes

ium

sulf

ate,

reduce

do

se 1

5 to

20%

in d

ebili

tate

d b

irds

Pen

tob

arb

ital

So

diu

mH

awk

14.7

IMP

RN

B10

86"

Pen

tob

arb

ital

So

diu

mP

engu

in33

NL

On

ceG

595

Pen

tob

arb

ital

So

diu

mP

igeo

n24

IMP

RN

B10

84A

dd c

hlo

ral h

ydra

te +

mag

nes

ium

sulf

ate,

reduce

do

se 1

5 to

20%

in d

ebili

tate

d b

irds

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

e

Page 65: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 305

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Pen

tob

arb

ital

So

diu

mQ

uai

l, Ja

pan

ese

25-5

0 g/

kg f

oo

dF

eed

On

ceB

1094

Pen

tob

arb

ital

So

diu

mR

apto

r<

20

PO

PR

NE

1463

Fo

r se

dat

ion

Pen

tob

arb

ital

So

diu

mR

apto

r30

IM-I

VP

RN

E14

63N

ot

usu

ally

rec

om

men

ded

Pen

tob

arb

ital

So

diu

mSk

ua,

McC

orm

ick'

s47

IM-I

VP

RN

B10

75

Pen

tob

arb

ital

So

diu

mSw

an, M

ute

25 m

g T

DIV

PR

NG

1074

Adult

Pen

tob

arb

ital

So

diu

mT

urk

ey16

.2IM

PR

NB

1080

Add t

hio

pen

tal s

odiu

m

Pen

toxif

yll

ine

Avi

an15

PO

BID

-TID

G14

89A

dd a

loe

vera

fo

r fr

ost

bit

e, v

aso

dila

tor

Perm

eth

rin

Pig

eon

dust

ing

To

pic

alN

LE

1240

Fo

r fl

eas

and li

ce

Per

met

hri

nP

sitt

acin

edust

ing

To

pic

alN

LE

1240

Ect

op

aras

ite

con

tro

l

Ph

en

ob

arb

ital

Avi

an1-

5P

OB

IDE

111,

147

3

Ph

eno

bar

bit

alA

vian

3.5-

7N

LB

IDD

1475

Co

ntr

ol o

f se

izure

s

Ph

eno

bar

bit

alA

vian

0.04

8-0.

080

g/L

Dri

nk

PR

NG

58

Ph

eno

bar

bit

alP

sitt

acin

e3

PO

BID

E12

40F

or

feat

her

pic

kin

g, m

ay c

ause

dee

p s

edat

ion

and in

abili

ty t

o p

erch

Ph

eno

bar

bit

alR

apto

r<

30

PO

PR

NE

1463

Fo

r se

dat

ion

Ph

eno

bar

bit

alR

apto

r20

PO

NL

D16

12F

or

neu

rolo

gic

sign

s w

ith

org

ano

chlo

rin

e

toxi

city

Ph

en

ylb

uta

zo

ne

Ost

rich

2.2

PO

QD

G71

0

Ph

enyl

buta

zon

eP

sitt

acin

e3.

5-7

PO

BID

-TID

E14

73

Ph

enyl

buta

zon

eR

apto

r3.

5-7

PO

BID

-TID

E11

1

Ph

yto

nad

ion

eA

vian

2.5-

5P

aren

tera

lB

ID-Q

IDE

1492

Fo

r an

tico

agula

nt

roden

tici

de

Ph

yto

nad

ion

eR

apto

r0.

2-2.

5IM

-PO

QD

E14

33F

or

anti

coag

ula

nt

po

iso

nin

g

Pip

era

cil

lin

So

diu

mA

maz

on

Par

rot

75-1

00IM

q4-

6hA

1473

Pip

erac

illin

So

diu

mA

vian

4.31

mg/

kcal

IM-I

VT

ID-Q

IDE

1180

Syn

ergi

stic

wit

h a

min

ogl

yco

sides

Pip

erac

illin

So

diu

mA

vian

2.55

mg/

kcal

IM-I

Vq4-

6hE

1180

Syn

ergi

stic

wit

h a

min

ogl

yco

sides

Pip

erac

illin

So

diu

mA

vian

10 g

/L

sal

ine

Flu

shB

ID-Q

IDE

1183

Nas

al o

r si

nus

Pip

erac

illin

So

diu

mA

vian

10 g

/L

sal

ine

Neb

uliz

eB

ID-Q

IDE

1185

10 t

o 3

0 m

inute

s

Pip

erac

illin

So

diu

mA

vian

100-

200

IMT

ID-Q

IDE

1650

Syn

ergi

stic

wit

h a

min

ogl

yco

sides

Pip

erac

illin

So

diu

mA

vian

150

IMB

IDG

55

Pip

erac

illin

So

diu

mB

ird, A

quat

ic10

0-20

0IM

BID

E14

78P

ost

-tra

um

a in

fect

ion

s

Pip

erac

illin

So

diu

mB

udge

riga

r20

0IM

TID

A41

1

Pip

erac

illin

So

diu

mC

ock

ato

o, C

itro

n-c

rest

ed90

Par

ente

ral

BID

G74

0A

dd a

mik

acin

Pip

erac

illin

So

diu

mC

ran

e10

0IM

-IV

-SC

BID

E62

9

Pip

erac

illin

So

diu

mD

uck

, Ruddy

100

IMB

IDG

1468

Beg

in p

re-o

per

ativ

ely

for

ten

do

n s

urg

ery

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 66: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I306

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Pip

erac

illin

So

diu

mF

alco

n20

0IM

TID

-QID

E10

27B

road

sp

ectr

um

Pip

erac

illin

So

diu

mG

ull

100

IMB

IDE

1357

Pip

erac

illin

So

diu

mL

ori

keet

, Rai

nb

ow

100

IMB

IDG

1620

Pip

erac

illin

So

diu

mM

acaw

4 m

g T

D p

er e

ggP

aren

tera

lq4d

G82

0F

or

emb

ryo

nic

dea

th, b

egin

fir

st d

ose

at

day

14, u

se 2

6 ga

nee

dle

Pip

erac

illin

So

diu

mP

igeo

n10

0IM

BID

-TID

G26

0

Pip

erac

illin

So

diu

mP

igeo

n10

0-20

0IM

BID

G59

0

Pip

erac

illin

So

diu

mP

sitt

acin

e10

0IM

BID

A41

1

Pip

erac

illin

So

diu

mP

sitt

acin

e50

-100

SCT

IDE

632

Neo

nat

e do

sage

Pip

erac

illin

So

diu

mP

sitt

acin

e10

0-20

0IM

-IV

BID

-TID

E12

40, 1

756

Pip

erac

illin

So

diu

mR

apto

r10

0IM

-IV

BID

E14

33

Pip

era

cil

lin

So

diu

m +

Tazo

bacta

m S

od

ium

Avi

an15

0-20

0IM

-IV

QD

-BID

G12

79Su

bst

itute

fo

r p

iper

acill

in s

odiu

m, D

O N

OT

use

am

ino

glyc

osi

des

co

ncu

rren

tly

Pip

erac

illin

So

diu

m +

Taz

ob

acta

m S

odiu

m

Fal

con

, Per

egri

ne

200

IMB

IDG

1426

Pip

era

zin

eA

nse

rifo

rmes

45-2

00P

ON

LE

111

Pip

eraz

ine

Avi

an10

0-50

0P

Oq2w

E16

50F

or

roun

dw

orm

s

Pip

eraz

ine

Cra

ne

4-5.

26 g

/L

Dri

nk

QD

G59

6R

epea

t in

2 w

eeks

Pip

eraz

ine

Fin

ch0.

3 g/

LD

rin

kN

LE

1572

Pip

eraz

ine

Gal

lifo

rmes

100-

500

PO

q2w

E11

1

Pip

eraz

ine

Pig

eon

1.9

g/L

Dri

nk

QD

C70

4F

or

30 b

irds

Pip

eraz

ine

Pig

eon

500

mg

Dri

nk

TD

C70

6F

or

cap

illar

ia

Pip

eraz

ine

Pig

eon

250

mg

Dri

nk

TD

C70

6F

or

asca

ridia

sis

Pip

eraz

ine

Pig

eon

12.5

Dri

nk

QD

E12

40R

epea

t ev

ery

10 t

o 1

4 day

s

Pip

eraz

ine

Pig

eon

35P

OQ

DG

260

Pip

eraz

ine

Po

ult

ry1

g/L

Dri

nk

QD

G57

Pip

eraz

ine

Po

ult

ry10

0-50

0P

Oq10

dG

1309

Fo

r as

cari

ds

Pip

eraz

ine

Psi

ttac

ine

250

PO

NL

G57

Pip

eraz

ine

Quai

l30

-50

mg

TD

PO

NL

G67

8A

nth

elm

inti

c

Pip

eraz

ine

Rap

tor

100

PO

NL

E57

, 146

3A

nth

elm

inti

c

Pip

ero

nyl

Bu

toxid

eR

apto

r6.

25 g

/L

To

pic

alN

LE

1068

Add p

erm

eth

rin

+ m

eth

op

ren

e fo

r

ecto

par

asit

es

Pir

oxic

am

Cra

ne

0.5

PO

BID

G16

71

Po

lico

san

ol

Am

azo

n P

arro

t1

mg

TD

PO

BID

G12

73F

or

hyp

erlip

idem

ia o

r h

yper

cho

lest

ero

lem

ia

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 67: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 307

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Po

lico

san

ol

Am

azo

n, Y

ello

w-n

aped

2P

OQ

DG

1466

Mix

wit

h la

ctulo

se f

or

hyp

erlip

idem

ia o

f

trig

lyce

ride

and c

ho

lest

ero

l

Po

lym

yxin

B S

ulf

ate

Avi

an10

-15

IM-P

ON

LE

924

Po

lym

yxin

B S

ulf

ate

Avi

an10

00 m

g/kc

alP

OB

IDE

1180

Po

lym

yxin

B S

ulf

ate

Avi

an30

00 K

IU/L

Dri

nk

NL

E11

80

Po

lym

yxin

B S

ulf

ate

Avi

an50

KIU

/kg

PO

BID

E56

5

Po

lym

yxin

B S

ulf

ate

Can

ary

50 K

IU/L

Dri

nk

QD

E69

5

Po

lym

yxin

B S

ulf

ate

Can

ary

50 K

IU/kg

fo

od

Fee

dQ

DE

695

Po

lym

yxin

B S

ulf

ate

Can

ary

500

KIU

/L

Dri

nk

NL

E11

87

Po

lym

yxin

B S

ulf

ate

Can

ary

500

KIU

/kg

fo

od

Fee

dO

nce

E11

87

Po

lym

yxin

B S

ulf

ate

Pas

seri

ne

100

KIU

/kg

fo

od

Fee

dQ

DE

1437

Add d

rug

to d

rin

k at

th

e sa

me

tim

e

Po

lym

yxin

B S

ulf

ate

Pas

seri

ne

100

KIU

/L

Dri

nk

QD

E14

37A

dd d

rug

to f

oo

d a

t th

e sa

me

tim

e

Po

lym

yxin

B S

ulf

ate

Pas

seri

ne,

Sm

all

500

KIU

/L

Dri

nk

NL

E11

87

Po

lym

yxin

B S

ulf

ate

Pas

seri

ne,

Sm

all

500

KIU

/kg

fo

od

Fee

dO

nce

E11

87

Po

lysu

lfate

d

Gly

co

sam

ino

gly

can

Cra

ne,

Dem

ois

elle

50 m

g T

DIA

On

ceG

579

Musc

ulo

sket

al jo

int

ther

apy

Po

lysu

lfat

ed

Gly

cosa

min

ogl

ycan

Ph

easa

nt,

Pea

cock

12.5

mg

TD

IMO

nce

G57

9M

usc

ulo

sket

al jo

int

ther

apy

Po

lysu

lfat

ed

Gly

cosa

min

ogl

ycan

Vult

ure

, Kin

g20

mg

TD

IMQ

WG

579

Musc

ulo

sket

al jo

int

ther

apy

Po

tass

ium

Bro

mid

eC

ock

ato

o, U

mb

rella

80P

OQ

DG

1691

Fo

r co

ntr

ol o

f se

izure

s

Po

tass

ium

Bro

mid

eP

arro

t, G

rey

80P

OQ

DG

1274

Seiz

ure

co

ntr

ol

Po

tass

ium

Bro

mid

eP

igeo

n80

PO

QD

G12

74Se

izure

co

ntr

ol

Po

tass

ium

Ch

lori

de

Avi

an0.

3IV

NL

E14

73

Po

tass

ium

Ch

lori

de

Avi

an0.

1-0.

3IV

NL

E11

1

Po

tass

ium

Perm

an

gan

ate

Fal

con

14 g

/m

³N

LO

nce

G10

29A

dd f

orm

aldeh

yde

for

fum

igat

ion

TO

XIC

Pra

lid

oxim

e C

hlo

rid

eA

vian

10-3

0IM

QD

E11

1

Pra

lido

xim

e C

hlo

ride

Rap

tor

100

NL

BID

-QID

E14

00F

or

org

ano

ph

osp

hat

e p

ois

on

ing

Pra

lido

xim

e C

hlo

ride

Rap

tor

20IM

PR

NG

50C

on

tin

ue

on

ly if

fir

st d

ose

pro

duce

s re

spo

nse

Pra

lid

oxim

e I

od

ide

Avi

an10

-100

Par

ente

ral

NL

E14

92R

educe

do

sage

if u

sed w

ith

atr

op

ine

for

org

ano

ph

osp

hat

es

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 68: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I308

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Pra

lido

xim

e Io

did

eA

vian

10-1

00P

aren

tera

lB

ID-T

IDE

1650

Use

low

er d

osa

ge if

use

d w

ith

atr

op

ine

for

org

ano

ph

osp

hat

e to

xici

ty

Pra

lido

xim

e Io

did

eR

apto

rs10

0IM

On

ceB

1093

Fo

r m

on

ocr

oto

ph

os

toxi

city

Pra

lid

oxim

e M

esy

late

An

seri

form

es10

0IM

QID

D11

50F

or

org

ano

ph

osp

hat

e to

xici

ty

Pra

lido

xim

e M

esyl

ate

Psi

ttac

ine

100

IMQ

IDE

1240

Pra

ziq

uan

tel

An

seri

form

es10

-20

PO

-SC

q10

dD

1150

Co

ntr

ol c

esto

des

Pra

ziquan

tel

Avi

an10

-20

PO

QD

D14

70F

or

liver

par

asit

ic d

isea

se

Pra

ziquan

tel

Avi

an9

IMQ

DD

1470

Co

nti

nue

PO

fo

r 11

day

s fo

r liv

er p

aras

itic

dis

ease

Pra

ziquan

tel

Avi

an10

PO

NL

E16

48F

or

tap

ewo

rms

Pra

ziquan

tel

Bir

d, A

quat

ic10

PO

NL

E15

03F

or

tap

ewo

rms

Pra

ziquan

tel

Bust

ard

10P

O-S

CO

nce

E12

40F

or

cest

odes

an

d t

rem

ato

des

Pra

ziquan

tel

Fin

ch10

-20

PO

q10

-14d

E15

72

Pra

ziquan

tel

Fin

ch12

mg/

kg

Fee

dO

nce

E16

17C

rush

tab

let

and m

ix w

ith

en

ough

fo

od f

or

1

day

, sca

tter

th

rough

out

avia

ry

Pra

ziquan

tel

Ost

rich

7.5

PO

NL

C28

3

Pra

ziquan

tel

Ost

rich

5P

ON

LG

481

Pra

ziquan

tel

Pas

seri

ne,

Sm

all

10N

LN

LE

1187

Fo

r tr

emat

odes

Pra

ziquan

tel

Pen

guin

10-2

0P

ON

LE

1478

Fo

r ce

sto

des

Pra

ziquan

tel

Pig

eon

11.4

SCQ

ME

704

Pra

ziquan

tel

Pig

eon

10-2

0P

Oq2w

E70

4T

able

t cr

ush

ed in

wat

er s

usp

ensi

on

Pra

ziquan

tel

Pig

eon

10P

ON

LE

1192

Fo

r ce

sto

des

Pra

ziquan

tel

Psi

ttac

ine

9IM

NL

E76

3F

or

tap

ewo

rms

Pra

ziquan

tel

Psi

ttac

ine

10-2

0P

OO

nce

E12

40F

or

tap

ewo

rms

rep

eat

afte

r 10

day

s

Pra

ziquan

tel

Rap

tor

50P

O-S

CN

LE

1068

Fo

r tr

emat

odes

an

d c

esto

des

Pra

ziquan

tel

Rap

tor

30N

Lq10

dE

1132

Fo

r ta

pew

orm

s an

d f

luke

s

Pra

ziquan

tel

Rap

tor

5-10

PO

-SC

QD

E12

40

Pra

ziquan

tel

Rap

tor

10-5

0P

Oq2w

E13

59F

or

tap

ewo

rms

Pre

dn

iso

lon

eA

vian

2P

OB

IDE

1431

May

pre

dis

po

se t

o m

yco

tic

infe

ctio

n

Pre

dn

iso

lon

eA

vian

6.7

PO

NL

E15

26U

se d

ecre

asin

g do

sage

fo

r lo

ng-

term

th

erap

y

Pre

dn

iso

lon

eP

sitt

acin

e2

PO

BID

E12

40A

lso

an

alge

sic

Pre

dn

iso

lon

eR

apto

r0.

5-1

IMO

nce

E14

00

Pre

dn

iso

lon

eR

apto

r2-

4IM

-IV

On

ceE

1400

Fo

r sh

ock

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 69: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 309

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Pre

dn

iso

lon

e S

od

ium

Ph

osp

hate

Avi

an0.

5-1

IM-I

VN

LE

111

Pre

dn

iso

lon

e So

diu

m

Ph

osp

hat

e

Avi

an2-

4IM

-IV

NL

E11

1Im

mun

osu

pp

ress

ive

Pre

dn

iso

lon

e So

diu

m

Ph

osp

hat

e

Rap

tor

10-3

0IM

-IV

PR

NG

234

Pre

dn

iso

lon

e S

od

ium

Su

ccin

ate

Avi

an0.

5-1

IM-I

VO

nce

E11

51F

or

neu

rolo

gic

emer

gen

cies

Pre

dn

iso

lon

e So

diu

m

Succ

inat

e

Avi

an10

-20

IM-I

VN

LD

1554

Fo

r sh

ock

Pri

maq

uin

e P

ho

sph

ate

Avi

an0.

03P

OQ

DD

1470

Fo

r liv

er p

aras

itic

dis

ease

Pri

maq

uin

e P

ho

sph

ate

Avi

an1

PO

QW

E14

79

Pri

maq

uin

e P

ho

sph

ate

Avi

an1

PO

QW

E14

92A

dd c

hlo

roquin

e fo

r P

lasm

odiu

m

Pri

maq

uin

e P

ho

sph

ate

Avi

an0.

3-1

PO

TID

G57

Usu

ally

in c

om

bin

atio

n w

ith

ch

loro

quin

e

Pri

maq

uin

e P

ho

sph

ate

Fal

con

0.75

NL

On

ceE

1177

Add c

hlo

roquin

e

Pri

maq

uin

e P

ho

sph

ate

Pen

guin

0.03

PO

QW

D14

70F

or

liver

par

asit

ic d

isea

se p

rop

hyl

axis

Pri

maq

uin

e P

ho

sph

ate

Pen

guin

0.03

PO

QD

E11

1, 1

473

Pri

maq

uin

e P

ho

sph

ate

Pen

guin

1P

OQ

DB

262

Add c

hlo

roquin

e p

ho

sph

ate

Pri

maq

uin

e P

ho

sph

ate

Psi

ttac

ine

1P

OQ

DE

1365

Fo

r sa

rco

cyst

osi

s

Pri

maq

uin

e P

ho

sph

ate

Rap

tor

1P

OQ

DG

61A

dd c

hlo

roquin

e

Pri

maq

uin

e P

ho

sph

ate

Rap

tor

1P

OQ

WG

94A

dd c

hlo

roquin

e p

ho

sph

ate,

juve

nile

do

sage

Pri

mid

on

eA

maz

on

Par

rot

125

mg

TD

Dri

nk

QD

G17

53L

on

g-te

rm s

eizu

re c

on

tro

l

Pri

mid

on

eR

apto

r12

5P

OP

RN

E14

63F

or

sedat

ion

Pro

ben

ecid

Avi

an20

0N

Lq2d

E70

4F

or

bo

dy

wei

ght

> 2

00g,

to

dec

reas

e

excr

etio

n r

ate

of

pen

icill

in/ce

ph

alo

spo

rin

duri

ng

ther

apy

Pro

ben

ecid

Mac

aw12

5P

OQ

IDG

45U

rico

siuri

c

Pro

bio

tic

An

seri

form

es21

ml/

kg f

oo

dF

eed

On

ceE

1240

Fo

r h

and-r

eari

ng

(6 h

ours

old

) an

d

con

vale

scin

g b

irds,

Avi

pro

Ped

iatr

ic®

Pro

bio

tic

An

seri

form

es5

sco

op

s/L

Dri

nk

NL

E12

40D

oub

le d

osa

ge f

or

stre

ssed

bir

d, A

vip

ro®

Pro

bio

tic

Avi

an5

cc/L

Fee

dO

nce

E11

1A

dd t

o h

and f

eedin

g fo

rmula

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 70: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I310

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Pro

bio

tic

Avi

an1

pin

ch T

DF

eed

QD

E11

1

Pro

bio

tic

Psi

ttac

ine

21 m

l/kg

fo

od

Fee

dO

nce

E12

40F

or

han

d-r

eari

ng

(6 h

ours

old

) an

d

con

vale

scin

g b

irds,

Avi

pro

Ped

iatr

ic®

Pro

bio

tic

Psi

ttac

ine

5 sc

oo

ps/

LD

rin

kN

LE

1240

Do

ub

le d

osa

ge f

or

stre

ssed

bir

d, A

vip

ro®

Pro

bio

tic

Psi

ttac

ine

5 m

l/L

fo

od

Fee

dO

nce

E14

73H

and f

eedin

g fo

rmula

Pro

bio

tic

Psi

ttac

ine

pin

ch T

DP

OQ

DE

1473

Pro

bio

tic

Rat

ite

PO

NL

G41

8

Pro

flavin

eA

vian

30 m

g T

DT

op

ical

QD

-BID

E12

40F

or

wo

un

ds,

sti

mula

te g

ran

ula

tio

n

Pro

pen

tofy

llin

eA

vian

5P

OQ

DG

1240

Vas

odila

tor

for

win

g ti

p e

dem

a o

r dry

gan

gren

e

Pro

pen

tofy

llin

eR

apto

r5

PO

BID

E14

00Im

pro

ve c

ircu

lati

on

(w

ing

tip

edem

a)

Pro

po

fol

Am

azo

n, H

isp

anio

lan

5IV

PR

NB

1436

Mai

nta

in a

nes

thes

ia b

y co

nti

nuo

us

infu

sio

n a

t

1 m

g/kg

per

min

ute

Pro

po

fol

An

seri

form

es8

IVP

RN

E11

90In

duct

ion

age

nt

Pro

po

fol

Avi

an1.

33-1

4IV

PR

NE

1181

Sho

rt d

ura

tio

n, s

mo

oth

induct

ion

, hig

h s

afet

y

mar

gin

Pro

po

fol

Duck

, Mal

lard

10IV

PR

NB

1358

Adm

inis

ter

ove

r 1

min

ute

, fo

llow

wit

h 4

mg/

kg, r

esp

irat

ory

dep

ress

ion

Pro

po

fol

Ost

rich

3IV

PR

NB

1628

Mai

nta

in w

ith

0.2

mg/

kg/m

in c

on

stan

t ra

te

infu

sio

n

Pro

po

fol

Pig

eon

4.1-

8.6

IVP

RN

B77

9F

ollo

ws

keta

min

e

Pro

po

fol

Pig

eon

14IV

PR

NB

779

Pre

limin

ary

to in

hal

atio

n a

nes

thes

ia

Pro

po

fol

Psi

ttac

ine

1.33

IVP

RN

E12

40F

or

anes

thes

ia in

duct

ion

Pro

po

fol

Swan

6IV

On

ceG

1695

Induct

ion

fo

r is

ofl

ura

ne

Pro

po

fol

Swan

(B

lack

, Mute)

10

IV

PR

N

B

1291

G

as a

nes

thes

ia p

rem

ed

Pro

po

lis

Ch

icke

n30

mg

TD

On

ceB

1632

Imm

un

e an

d g

row

th s

tim

ula

nt

Pro

pra

no

lol

HC

lA

vian

0.2

IMN

LE

111

Pro

pra

no

lol H

Cl

Avi

an0.

04IV

NL

E11

1

Pro

stag

lan

din

E (

See

Din

op

rost

on

e)

Rap

tor

N/A

To

pic

alP

RN

E14

00F

or

egg

bin

din

g, u

se g

el f

orm

ula

tio

n

Psy

lliu

m H

yd

rop

hil

ic

Mu

cil

loid

Avi

an2.

5 m

l/kg

PO

NL

G87

Mix

wit

h s

yrin

geab

le f

oo

d, b

ulk

ing

agen

t to

rem

ove

GI

mat

eria

ls

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 71: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 311

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Psy

llium

Hyd

rop

hili

c

Muci

lloid

Bir

d, A

quat

ic40

ml/

L s

oft

fo

od

Fee

dO

nce

E14

78A

dd s

odiu

m +

mag

nes

ium

sulf

ate

+ m

iner

al

oil

for

lead

po

iso

nin

g, a

dd b

ran

Pyra

nte

l P

am

oate

An

seri

form

es7

PO

q2w

E13

58F

or

nem

ato

des

Pyr

ante

l Pam

oat

eA

vian

4.5-

25P

Oq2w

D11

1,12

21, 1

473

Fo

r n

emat

odia

sis

Pyr

ante

l Pam

oat

eC

ran

e4.

5P

Oq10

dE

1361

Fo

r in

test

inal

nem

ato

des

Pyr

ante

l Pam

oat

eF

inch

4.5

PO

q10

-14d

E15

72

Pyr

ante

l Pam

oat

eP

asse

rin

e10

0P

OO

nce

G13

35F

or

inte

stin

al n

emat

odes

Pyr

ante

l Pam

oat

eP

igeo

n20

-25

PO

QW

-q2w

E13

64

Pyr

ante

l Pam

oat

eP

sitt

acin

e4.

5P

Oq10

dE

1240

Fo

r n

emat

odes

Pyr

ante

l Pam

oat

eP

sitt

acin

e10

0P

ON

LG

57, 1

335

Pyr

ante

l Pam

oat

eR

apto

r20

PO

On

ceE

1240

, 140

0F

or

nem

ato

des

Pyr

ante

l Pam

oat

eR

apto

r4.

5P

Oq2w

G94

Juve

nile

do

sage

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ante

l Pam

oat

eR

atit

e5-

7P

ON

LG

418

Pyre

thri

nC

ran

e0.

1% p

ow

der

To

pic

alQ

W-q

2wE

1361

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r ec

top

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ites

, ap

ply

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tly

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eth

rin

Fin

chT

op

ical

QD

E15

72D

ust

fea

ther

s

Pyr

eth

rin

Rap

tor

0.5-

2% m

ixtu

reT

op

ical

q10

dG

1411

Fo

r ch

ewin

g lic

e

Pyri

meth

am

ine

An

seri

form

es0.

25-0

.5P

OB

IDD

1150

Fo

r sa

rco

cyst

osi

s an

d t

oxo

pla

smo

sis

Pyr

imet

ham

ine

Avi

an0.

5P

OB

IDD

1470

Pyr

imet

ham

ine

Avi

an0.

3P

ON

LE

1650

Fo

r L

euco

cyto

zoo,

Pla

smod

ium

Pyr

imet

ham

ine

Rap

tor

0.25

-0.5

PO

BID

E14

00F

or

sarc

ocy

sto

sis,

to

xop

lasm

osi

s an

d o

ther

pro

tozo

al in

fect

ion

s

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imet

ham

ine

Rap

tor

0.5

PO

BID

E14

33F

or

leuco

cyto

zoo

no

sis

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meth

am

ine +

Su

lfaq

uin

oxali

ne

An

seri

form

es0.

06 g

/L

Dri

nk

QD

D11

502

day

s o

ff, t

hen

rep

eat

for

cocc

idio

sis

Pyr

imet

ham

ine

+

Sulf

aquin

oxa

line

Psi

ttac

ine

0.06

g/L

Dri

nk

QD

E12

40W

ait

2 day

s th

en r

epea

t fo

r co

ccid

iosi

s

Qu

inacri

ne H

Cl

Avi

an5-

10P

OQ

DE

111

Quin

acri

ne

HC

lA

vian

240

NL

QD

E14

79F

or

Pla

smod

ium

Quin

acri

ne

HC

lA

vian

7.5

PO

QD

E16

50F

or

Pla

smod

ium

Quin

acri

ne

HC

lC

anar

y24

0P

OB

IDG

57

Quin

acri

ne

HC

lP

igeo

n10

mg

TD

PO

QD

G47

Quin

acri

ne

HC

lP

sitt

acin

e5-

10P

OQ

DE

1473

Red

Clo

ver

Avi

an10

dro

ps/

kgP

OQ

DE

1435

Use

low

alc

oh

ol f

orm

ula

tio

n f

or

soft

sh

elle

d

egg

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 72: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I312

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Red

Palm

Oil

Avi

an10

-60

dro

ps/

kgP

OQ

DG

1727

May

giv

e o

ver

foo

d

Resc

ue R

em

ed

yF

inch

2 dro

ps

TD

PO

On

ceG

1723

Fo

r st

ress

of

han

dlin

g o

r m

ino

r p

roce

dure

s

Rese

rpin

eR

apto

r2-

4P

OP

RN

E14

63F

or

pro

lon

ged s

edat

ion

Reso

ran

tel

Ost

rich

130

PO

NL

B28

3,40

1, 5

24A

dd f

enb

endaz

ole

or

leva

mis

ole

Rif

ab

uti

nA

vian

15P

OQ

DD

1470

Add e

tham

buto

l + e

nro

flo

xaci

n f

or

myc

ob

acte

rio

sis

Rif

abuti

nA

vian

1.15

mg/

kcal

PO

QD

E11

80A

dd e

tham

buto

l + a

zith

rom

ycin

or

clar

ith

rom

ycin

fo

r m

yco

bac

teri

osi

s

Rif

am

pin

Am

azo

n, Y

ello

w-c

hee

ked

45N

LQ

DG

713

Add e

tham

buto

l + is

on

iazi

d

Rif

amp

inA

vian

10-2

0P

OB

IDE

111,

147

3

Rif

amp

inA

vian

15P

OQ

DG

1154

Add c

ipro

flo

xaci

n +

eth

amb

uto

l fo

r

myc

ob

acte

rio

sis

Rif

amp

inB

ust

ard, H

oub

ara

20P

OB

IDG

932

Fo

r b

acte

rial

dia

rrh

ea

Rif

amp

inC

ran

e, W

ho

op

ing

45P

OQ

DG

207

Add e

tham

buto

l

Rif

amp

inP

sitt

acin

e15

PO

BID

E12

40F

or

avia

n t

ub

ercu

losi

s

Rif

amp

inR

apto

r30

PO

TID

B11

78A

dd I

T a

nd I

V a

mp

ho

teri

cin

B +

flu

cyto

sin

e

for

asp

ergi

llosi

s

Rim

an

tad

ine H

Cl

Po

ult

ry0.

1 g/

LD

rin

kN

LG

435

Ro

ben

idin

e H

Cl

Ch

icke

n33

mg/

kg f

oo

dF

eed

QD

E56

47-

day

sla

ugh

ter

wit

hdra

wal

, pro

ph

ylac

tic

Ro

ben

idin

e H

Cl

Ph

easa

nt,

Rin

g-n

ecke

d0.

033

g/kg

Fee

dQ

DB

895

Fo

r co

ccid

iosi

s

Ro

nid

azo

leA

vian

0.32

3 m

g/kc

alP

OQ

DE

1180

Fo

r fl

agel

late

s

Ro

nid

azo

leA

vian

0.65

g/L

Dri

nk

NL

E11

80

Ro

nid

azo

leA

vian

1 g/

LD

rin

kQ

DE

1479

Tre

at 4

tim

es y

earl

y fo

r T

rich

om

on

iasi

s

Ro

nid

azo

leA

vian

6-10

PO

QD

G57

Ro

nid

azo

leB

udge

riga

r1

g/L

Dri

nk

QD

E14

79T

reat

4 t

imes

yea

rly

for

Tri

cho

mo

nia

sis

Ro

nid

azo

leC

anar

y0.

4 g/

LD

rin

kQ

DE

695

Ro

nid

azo

leC

anar

y0.

4 g/

kg f

oo

dF

eed

On

ceE

1187

Ro

nid

azo

leF

inch

0.1

g/L

Dri

nk

QD

E15

72

Ro

nid

azo

leF

inch

6-10

PO

QD

E15

72

Ro

nid

azo

leF

inch

0.05

g/kg

fo

od

Fee

dQ

DG

1334

Fo

r co

chlo

som

iasi

s

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 73: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 313

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Ro

nid

azo

leF

inch

0.05

g/L

Dri

nk

QD

G13

34F

or

coch

loso

mia

sis

Ro

nid

azo

leP

asse

rin

e0.

04 g

/L

Dri

nk

QD

D14

38F

or

tric

ho

mo

nia

sis,

gia

rdia

sis

and

coch

loso

mia

sis

Ro

nid

azo

leP

igeo

n6-

10N

LQ

DD

1221

Fo

r tr

ich

om

on

iasi

s

Ro

nid

azo

leP

igeo

n0.

1 g/

LD

rin

kQ

DE

1192

Fo

r h

exam

itia

sis,

add t

rim

eth

op

rim

or

enro

flo

xaci

n in

sev

ere

infe

ctio

ns

Ro

nid

azo

leP

igeo

n0.

1-0.

2 g/

LD

rin

kN

LE

1192

Fo

r tr

eatm

ent

of

tric

ho

mo

nia

sis,

giv

e

per

iodic

ally

fo

r 2

to 3

day

s fo

r p

rop

hyl

axis

Ro

nid

azo

leP

igeo

n12

.5D

rin

kQ

DE

1240

Fo

r tr

ich

om

on

iasi

s tr

eatm

ent

Ro

nid

azo

le

Pig

eon

10

P

O

NL

E

14

32

"

Ro

nid

azo

le

Pig

eon

0.

1 g/

L

Dri

nk

NL

E

14

32

"

Ro

xars

on

eP

oult

ry25

-50

mg/

kg f

oo

dF

eed

QD

E56

4N

utr

itio

nal

use

, no

sla

ugh

ter

wit

hdra

wal

Sali

cyli

c A

cid

Psi

ttac

ine

To

pic

alq2w

D14

46A

dd 3

g t

ann

ic a

cid +

3 g

sal

icyl

ic a

cid +

eth

yl a

lco

ho

l fo

r 10

0 m

l of

solu

tio

n f

or

der

mat

om

yco

sis

Sali

no

mycin

Ch

icke

n0.

06 g

/kg

Fee

dQ

DB

869

Pre

ven

tive

fo

r co

ccid

iosi

s

Salin

om

ycin

Ch

icke

n0.

075

g/kg

Fee

dQ

DB

869

Pre

ven

tive

fo

r co

ccid

iosi

s

Salin

om

ycin

Ch

icke

n60

Fee

dQ

DB

958

Fo

r co

ccid

ial p

rop

hyl

axis

Salin

om

ycin

Ch

icke

n44

-66

mg/

kg f

oo

dF

eed

QD

E56

4N

o s

laugh

ter

wit

hdra

wal

, pro

ph

ylac

tic

Salin

om

ycin

Ph

easa

nt,

Rin

g-n

ecke

d60

pp

mF

eed

On

ceB

783

Fo

r co

ccid

iosi

s

Salin

om

ycin

Po

ult

ry60

g/to

nF

eed

QD

C70

5F

or

cocc

idio

sis

Sara

flo

xacin

HC

lC

hic

ken

10P

OB

ID-T

IDA

787

Sara

flo

xaci

n H

Cl

Ch

icke

n8

Dri

nk

QD

B85

5C

on

tin

uo

us

or

4-h

our

puls

e do

se

Sara

flo

xaci

n H

Cl

Ch

icke

n0.

02 g

/L

Dri

nk

QD

B86

4F

or

Esc

heri

chia

col

i in

fect

ion

s

Sara

flo

xaci

n H

Cl

Turk

ey0.

05 g

/L

Dri

nk

NL

A80

5

Seco

barb

ital

So

diu

mB

lack

bir

d, R

ed-w

inge

d0.

025-

0.03

PO

PR

NG

1769

Add c

hlo

ralo

se

Seco

bar

bit

al S

odiu

mD

ove

5 g/

L b

ait

Fee

dO

nce

G17

63B

ait

is u

sual

ly c

orn

Seco

bar

bit

al S

odiu

mD

uck

, Mal

lard

25P

OP

RN

B10

95

Sele

niu

mP

sitt

acin

e0.

06N

Lq3d

-q2w

G16

13

Sem

du

ram

ycin

Ch

icke

nP

OQ

DG

564

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 74: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I314

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Sero

mycin

Avi

an10

PO

BID

G11

54A

dd la

mp

ren

e +

eth

amb

uto

l HC

l, ad

d

cip

rofl

oxa

cin

or

enro

flo

xaci

n o

r st

rep

tom

ycin

for

adva

nce

d c

ases

Sil

ver

Nit

rate

Avi

anT

op

ical

q10

dE

1650

Fo

r ca

ute

ry o

f p

apill

om

as

Sil

ver,

Co

llo

idal

Avi

an2

dro

ps/

kgP

OQ

DE

1435

Bro

ad s

pec

trum

Silv

er, C

ollo

idal

Avi

an40

dro

ps/

LD

rin

kQ

DE

1435

Bro

ad s

pec

trum

So

diu

m B

icarb

on

ate

Avi

an1

mE

q/kg

IV-S

CP

RN

G13

09F

irst

do

se I

V, r

emai

nder

SC

, max

imum

to

tal

do

se 4

mE

q/kg

fo

r m

etab

olic

aci

do

sis

Sodiu

m B

icar

bo

nat

eA

vian

1-4

mE

q/kg

IVN

LE

1473

Giv

e sl

ow

ly o

ver

15 t

o 3

0 m

inute

s, d

o n

ot

exce

ed 4

mE

q/kg

Sodiu

m B

icar

bo

nat

eA

vian

5 m

Eq/kg

IO-I

VO

nce

G13

11F

or

card

iop

ulm

on

ary

resu

scit

atio

n

So

diu

m C

hlo

rid

e

Avi

an

30 m

l/kg

P

O T

ID-Q

ID E

11

51 U

se 0

.9%

so

luti

on

Sodiu

m C

hlo

ride

Bir

d, A

quat

ic10

g/L

Gav

age

QD

D15

59T

o m

ain

tain

act

ivit

y o

f sa

lt g

lan

d o

f m

arin

e

bir

ds

kep

t o

n f

resh

wat

er

Sodiu

m C

hlo

ride

Bir

d, A

quat

ic10

0F

eed

QD

E15

01F

or

pel

agic

sea

bir

ds

kep

t in

fre

sh w

ater

Sodiu

m C

hlo

ride

Bir

d, A

quat

ic10

0P

ON

LE

1503

Fo

r p

roce

llifo

rm b

irds

kep

t in

fre

sh w

ater

Sodiu

m C

hlo

ride

Pen

guin

150-

1667

PO

QD

G13

53Su

pp

lem

ent

fish

die

t

Sodiu

m C

hlo

ride

Psi

ttac

ine

50 m

l/kg

IM-I

V-S

C

Q

D E

1240

Use

0.9

% s

olu

tio

n

Sodiu

m C

hlo

ride

Rap

tor

1-2%

so

luti

on

T

op

ical

N

L

E

1400

1-

2% s

olu

tio

n f

or

wo

un

ds,

was

h o

ff w

ith

in 5

min

ute

s

So

diu

m H

yp

och

lori

teF

inch

30 m

l/L

To

pic

alN

LE

1572

Fo

r sa

lmo

nel

losi

s en

viro

nm

enta

l cle

anup

, use

ho

use

ho

ld b

leac

h

So

diu

m I

od

ide

Avi

an60

IMP

RN

G54

Sodiu

m I

odid

eA

vian

67-2

00IM

NL

F12

09

Sodiu

m I

odid

eB

udge

riga

r2

mg

TD

IMP

RN

G85

Sodiu

m I

odid

eB

udge

riga

r13

4-20

0IM

QD

G12

12F

or

acute

th

yro

id h

yper

pla

sia

Sodiu

m I

odid

eB

udge

riga

r67

IMQ

DG

1212

Fo

r ch

ron

ic t

hyr

oid

hyp

erp

lasi

a

So

diu

m L

acta

te S

olu

tio

nA

vian

50 m

l/kg

IVN

LE

111

Mai

nte

nan

ce f

luid

s

Sodiu

m L

acta

te S

olu

tio

nA

vian

10-3

0 m

l/kg

IVN

LE

1650

Em

erge

ncy

car

e, g

ive

slo

wly

, war

m f

luid

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 75: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 315

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Sodiu

m L

acta

te S

olu

tio

nA

vian

25 m

l/kg

IO-I

V-S

CN

LG

1311

Sodiu

m L

acta

te S

olu

tio

nA

vian

50-1

00 m

l/kg

IO-I

V-S

CB

IDG

1756

Fo

r h

yper

uri

cem

ia, g

ive

un

til l

evel

dro

ps

to

no

rmal

Sodiu

m L

acta

te S

olu

tio

nH

awk,

Red

-tai

led

20 m

l/kg

IVN

LG

1626

Sup

po

rtiv

e th

erap

y p

ost

-tra

um

a

Sodiu

m L

acta

te S

olu

tio

nL

ory

, Red

50 m

l/kg

SCN

LG

1621

Intr

a-o

per

ativ

e fl

uid

s

Sodiu

m L

acta

te S

olu

tio

nP

sitt

acin

e50

-100

ml/

kgIO

-IP

-IV

-SC

NL

E16

88

So

diu

m S

ulf

ate

Avi

an20

00P

OQ

DE

111

Lar

ge b

irds,

giv

e sl

urr

y

Sodiu

m S

ulf

ate

Avi

an50

0-10

00P

ON

LE

1554

Fo

r b

otu

lism

to

flu

sh g

astr

oin

test

inal

tra

ct

Sodiu

m S

ulf

ate

Avi

an12

5-25

0P

ON

LG

1746

Fo

r re

mo

val o

f m

etal

s fr

om

GI

trac

t

So

mato

stati

nT

ouca

n, S

ulf

ur-

bre

aste

d0.

003

SCB

IDG

589

Sp

ecti

no

mycin

HC

lA

vian

30P

OQ

DE

565

Spec

tin

om

ycin

HC

lA

vian

1 g/

LD

rin

kQ

DE

704

Spec

tin

om

ycin

HC

lA

vian

10-4

5IM

NL

E70

4

Spec

tin

om

ycin

HC

lA

vian

0.58

mg/

kcal

IM-S

CT

IDE

1180

Spec

tin

om

ycin

HC

lA

vian

1 g/

LD

rin

kN

LE

1180

Spec

tin

om

ycin

HC

lC

anar

y0.

2-0.

4 g/

LD

rin

kN

LE

1187

Spec

tin

om

ycin

HC

lC

hic

ken

5 m

g T

DSC

On

ceB

848

Day

-old

neo

nat

es

Spec

tin

om

ycin

HC

lC

hic

ken

2 g/

LD

rin

kN

LC

1307

Fo

r M

ycop

lasm

a ga

llise

pticum

in b

roile

rs

Spec

tin

om

ycin

HC

lC

hic

ken

0.5

g/L

Dri

nk

NL

C13

07F

or

imp

rove

d w

eigh

t ga

in in

bro

ilers

Spec

tin

om

ycin

HC

lD

uck

5SC

On

ceB

841

Fo

r E

. col

i an

d S

alm

onel

la

Spec

tin

om

ycin

HC

lF

inch

0.2-

0.4

g/L

Dri

nk

QD

E15

72

Spec

tin

om

ycin

HC

lF

inch

0.4

g/kg

fo

od

Fee

dQ

DE

1572

Spec

tin

om

ycin

HC

lP

asse

rin

e0.

2-0.

4 g/

LD

rin

kQ

DE

1437

Add d

rug

to f

oo

d a

t th

e sa

me

tim

e

Spec

tin

om

ycin

HC

lP

asse

rin

e0.

4 g/

kg s

oft

fo

od

Fee

dQ

DE

1437

Add d

rug

to d

rin

k at

th

e sa

me

tim

e

Spec

tin

om

ycin

HC

lP

asse

rin

e, S

mal

l0.

4 g/

kg f

oo

dF

eed

On

ceE

1187

Spec

tin

om

ycin

HC

lP

asse

rin

e, S

mal

l0.

2-0.

4 g/

LD

rin

kN

LE

1187

Spec

tin

om

ycin

HC

lP

igeo

n25

IM-S

CT

IDE

565,

106

1

Spec

tin

om

ycin

HC

lP

igeo

n30

PO

QD

F10

61

Spec

tin

om

ycin

HC

lP

igeo

n0.

15-0

.25

g/L

Dri

nk

NL

G26

0

Spec

tin

om

ycin

HC

lP

oult

ry0.

264-

0.53

g/L

Dri

nk

QD

C56

4

Spec

tin

om

ycin

HC

lP

oult

ry0.

132

g/L

Dri

nk

QD

C56

4P

rop

hyl

acti

c

Spec

tin

om

ycin

HC

lP

oult

ry2.

5-20

mg

TD

SCQ

DC

564

Ch

ick

do

sage

Spec

tin

om

ycin

HC

lP

sitt

acin

e10

-30

IMB

ID-T

IDE

1240

Gra

m n

egat

ive

ente

riti

s

Spec

tin

om

ycin

HC

lP

sitt

acin

e35

INN

LE

1240

Giv

e 1/

3 ea

ch n

are,

rem

ain

der

IM

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 76: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I316

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Spec

tin

om

ycin

HC

lR

apto

r50

IMB

IDG

234

Spec

tin

om

ycin

HC

lT

urk

ey12

.5-2

5 m

g T

DSC

NL

C13

07D

ilute

1:4

no

rmal

sal

ine

for

new

ly h

atch

ed

chic

ks

Spec

tin

om

ycin

HC

lT

urk

ey10

mg

TD

SCN

LC

1307

Inje

ct in

bas

e o

f th

e n

eck

of

1 to

3-d

ay-o

ld

po

ult

s fo

r ai

rsac

culit

is

Sp

iram

ycin

Avi

an25

0P

OQ

DE

565

Spir

amyc

inA

vian

100

IM-P

ON

LE

924

Spir

amyc

inA

vian

2 g/

LD

rin

kN

LE

1180

Spir

amyc

inA

vian

0.58

mg/

kcal

IMQ

DE

1180

Spir

amyc

inA

vian

1.08

mg/

kcal

PO

QD

E11

80

Spir

amyc

inC

anar

y0.

2-0.

4 g/

LD

rin

kQ

DE

695

Spir

amyc

inC

anar

y40

0 m

g/kg

fo

od

Fee

dQ

DE

695

Spir

amyc

inP

asse

rin

e, S

mal

l0.

2-0.

4 g/

LD

rin

kN

LE

1187

Spir

amyc

inP

asse

rin

e, S

mal

l0.

4 g/

kg f

oo

dF

eed

On

ceE

1187

Spir

amyc

inP

igeo

n25

IMQ

DE

565,

106

1

Spir

amyc

inP

igeo

n50

PO

QD

F10

61

Spir

amyc

inP

oult

ry0.

4 g/

LD

rin

kQ

DC

564

Spir

amyc

inR

apto

r20

IMN

LE

1463

Fo

r b

acte

rial

infe

ctio

ns

Sta

no

zo

lol

Avi

an25

-50

IMq3d

-QW

E11

1, 1

209,

124

0

Stan

ozo

lol

Avi

an25

-50

IMq3-

4dE

1473

Stan

ozo

lol

Avi

an25

-50

IMq3d

-QW

G13

09A

nab

olic

age

nt

Stan

ozo

lol

Psi

ttac

ine

0.01

6 g/

LD

rin

kN

LE

763

Fo

r deb

ilita

tio

n, a

no

rexi

a an

d a

nem

ia

Stan

ozo

lol

Psi

ttac

ine

0.5-

1P

aren

tera

lN

LE

763

Fo

r deb

ilita

tio

n, a

no

rexi

a an

d a

nem

ia

Str

ep

tom

ycin

Su

lfate

Avi

an10

-30

IMB

ID-T

IDE

111

Stre

pto

myc

in S

ulf

ate

Avi

an33

IMB

ID-T

IDE

741

Use

d in

larg

e b

irds

and p

oult

ry

Stre

pto

myc

in S

ulf

ate

Avi

an15

IM-P

ON

LE

924

Po

or

spec

trum

Stre

pto

myc

in S

ulf

ate

Avi

an0.

65 m

g/kc

alIM

BID

-TID

E11

80

Stre

pto

myc

in S

ulf

ate

Avi

an1.

28-4

.67

mg/

kcal

PO

QD

E11

80

Stre

pto

myc

in S

ulf

ate

Avi

an10

-30

IMB

ID-T

IDE

1470

Stre

pto

myc

in S

ulf

ate

Avi

an30

IMB

IDG

55, 1

154

Add e

tham

buto

l + r

ifam

pin

fo

r

myc

ob

acte

rio

sis

Stre

pto

myc

in S

ulf

ate

Avi

an10

IMB

IDG

819

Add r

ifam

pin

+ e

tham

buto

l fo

r av

ian

tub

ercu

losi

s

Stre

pto

myc

in S

ulf

ate

Ch

icke

n25

-50

IMQ

DA

320

Stre

pto

myc

in S

ulf

ate

Ch

icke

n50

-100

PO

QD

E56

5

Stre

pto

myc

in S

ulf

ate

Ph

easa

nt

220

mg/

kg f

oo

dF

eed

QD

G67

8

Stre

pto

myc

in S

ulf

ate

Ph

easa

nt

55-1

10 m

g/kg

fo

od

Fee

dQ

DG

678

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 77: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 317

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Stre

pto

myc

in S

ulf

ate

Pig

eon

100-

200

PO

QD

E56

5, 1

061

Stre

pto

myc

in S

ulf

ate

Pig

eon

25-5

0IM

QD

F10

61

Stre

pto

myc

in S

ulf

ate

Po

ult

ry55

PO

QD

C56

4

Stre

pto

myc

in S

ulf

ate

Po

ult

ry0.

068-

0.1

g/L

Dri

nk

QD

C56

4

Stre

pto

myc

in S

ulf

ate

Po

ult

ry13

.2 m

g/kg

fo

od

Fee

dQ

DE

564

Add p

enic

illin

, nutr

itio

nal

use

, no

sla

ugh

ter

wit

hdra

wal

Stre

pto

myc

in S

ulf

ate

Quai

l55

-110

mg/

kg f

oo

dF

eed

QD

G67

8

Stre

pto

myc

in S

ulf

ate

Rap

tor

15P

ON

LE

1463

May

giv

e w

ith

kao

lin o

r su

lfo

nam

ide

for

bac

teri

al in

fect

ion

s

Su

ccim

er

Avi

an25

-35

PO

BID

D12

21, 1

470

Pre

ferr

ed o

ral d

rug

for

lead

to

xico

sis

Succ

imer

Avi

an30

PO

QD

E11

20F

or

zin

c to

xico

ses

Succ

imer

Avi

an30

PO

BID

E11

51M

etal

ch

elat

ing

agen

t

Succ

imer

Avi

an25

-35

PO

BID

E12

36G

ive

5 day

s p

er w

eek

for

lead

to

xico

sis

Succ

imer

Avi

an15

-35

PO

BID

G13

37F

or

lead

po

iso

nin

g

Succ

imer

Bir

d, A

quat

ic25

-35

PO

BID

D14

78

Succ

imer

Psi

ttac

ine

30N

LN

LG

1710

Fo

r zi

nc

toxi

city

Succ

imer

R

apto

r 25

P

O

BID

E

13

59

Aft

er 2

day

s o

ff, r

epea

t o

ver

3-5

wee

ks f

or

lead

to

xici

ty

Su

cra

lfate

Avi

an25

PO

TID

E14

92M

ix w

ith

wat

er f

or

GI

ble

edin

g

Sucr

alfa

teL

ori

keet

, Rai

nb

ow

24P

OB

IDG

1620

Fo

r in

test

inal

ulc

ers

Sucr

alfa

te

Psi

ttac

ine

25

PO

T

ID

E

111

Su

cro

seR

apto

r<

5 m

l/kg

5%

so

lnP

OP

RN

E14

00M

ild p

urg

ativ

e, m

ay s

tim

ula

te a

pp

etit

e

Su

lfach

lorp

yri

dazin

e

Avi

an

0.17

5 g/

L

Dri

nk

QD

E

12

40 A

nti

bac

teri

al,*

use

5-1

0 day

s

Sulf

ach

lorp

yrid

azin

e A

vian

0.

125

ml p

ow

der

D

rin

k Q

Dlll

llll

G

1309

A

nti

bac

teri

al*

*

Vet

isulid

Ora

l Po

wder

® is

560

mg/

ml

vo

lum

e fo

r fl

ock

tre

atm

ent

for

E. c

oli

Sulf

ach

lorp

yrid

azin

e A

vian

5

9 g/

L D

rin

k Q

D

E

1479

U

se 5

day

s p

er w

eek,

red

uce

s sh

eddin

g o

f

Ato

xop

lasm

a

Sulf

ach

lorp

yrid

azin

e A

vian

0.

4 g/

L

Dri

nk

QD

G

57

R

epea

t af

ter

2 day

s, a

nti

par

asit

ic

Sulf

ach

lorp

yrid

azin

eC

anar

y0.

15 g

/L

Dri

nk

QD

-q2d

E11

87G

ive

5 day

s p

er w

eek

un

til m

olt

ing

com

ple

te

in ju

ven

iles

wit

h a

toxo

pas

mo

sis

Sulf

ach

lorp

yrid

azin

eC

anar

y0.

3 g/

LD

rin

kQ

D-q

2dE

1187

Giv

e 5

day

s p

er w

eek

for

cocc

idio

sis

Sulf

ach

lorp

yrid

azin

eC

anar

y0.

15-.

0.3

g/L

Dri

nk

NL

E11

87

Sulf

ach

lorp

yrid

azin

eP

asse

rin

e0.

15 g

/L

Dri

nk

QD

G13

34G

ive

5 day

s o

f ea

ch w

eek,

co

nti

nue

un

til a

fter

mo

ltin

g

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 78: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I318

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Sulf

ach

lorp

yrid

azin

eP

asse

rin

e, S

mal

l0.

15-.

0.3

g/L

Dri

nk

NL

E11

87

Sulf

ach

lorp

yrid

azin

eP

igeo

n0.

3 g/

LD

rin

kQ

DG

260

Sulf

ach

lorp

yrid

azin

eP

igeo

n0.

3 g/

LD

rin

kQ

DG

260

Su

lfad

iazin

e,

Sil

ver

Psi

ttac

ine

1% c

ream

fo

rmula

To

pic

alN

LD

1448

Po

st-s

urg

ical

wo

un

d c

are

Su

lfad

iazin

e,

Su

lfam

era

zin

e,

Su

lfam

eth

azin

e

Pen

guin

, Afr

ican

300-

400

Fee

dB

IDD

1614

Pre

cede

wit

h s

ulf

amet

haz

ine

inje

ctab

le, g

ive

do

se in

fis

h f

or

mal

aria

Su

lfad

imeth

oxin

eA

vian

24IM

NL

F12

09

Sulf

adim

eth

oxi

ne

Avi

an25

IM-P

ON

LE

924

Sulf

adim

eth

oxi

ne

Ch

icke

n0.

5 g/

LD

rin

kN

LB

826

Fo

r P

aste

urel

la m

ulto

cida

an

d H

emop

hilu

s

galli

naru

m

Sulf

adim

eth

oxi

ne

Cra

ne

50P

OQ

DE

1361

Fo

r co

ccid

iosi

s

Sulf

adim

eth

oxi

ne

Fal

con

25 (

50 lo

adin

g do

se)

PO

QD

E10

27F

or

cocc

idio

sis,

do

no

t dep

rive

of

wat

er

Sulf

adim

eth

oxi

ne

Gull

25P

OB

IDE

1357

cocc

idio

sis

Sulf

adim

eth

oxi

ne

Pig

eon

25P

OB

IDG

590

Sulf

adim

eth

oxi

ne

Pig

eon

250

IMB

IDA

992

Fo

r co

ccid

iosi

s

Sulf

adim

eth

oxi

ne

Pig

eon

0.

5 g/

L

Dri

nk

QD

E

14

32

Fo

r co

ccid

iosi

s an

d a

toxo

pla

smo

sis

Sulf

adim

eth

oxi

ne

Pig

eon

0.19

-0.2

5 g/

LD

rin

kQ

DG

260

Lo

adin

g do

se 3

75 m

g/L

Sulf

adim

eth

oxi

ne

Po

ult

ry0.

25-0

.5 g

/L

Dri

nk

QD

C56

4

Sulf

adim

eth

oxi

ne

Rap

tor

25N

LQ

DE

1132

Do

ub

le d

ose

fo

r fi

rst

day

fo

r co

ccid

iosi

s

Sulf

adim

eth

oxi

ne

Rap

tor

25-5

0P

OQ

DG

94Ju

ven

ile d

osa

ge, r

epea

t af

ter

2 day

s

Su

lfad

oxin

e +

Pyri

meth

am

ine

Avi

an1

PO

QW

E14

79

Sulf

ado

xin

e +

Pyr

imet

ham

ine

Avi

an0.

3P

ON

LE

1650

Do

sage

bas

ed o

n p

yrim

eth

amin

e fo

r

Leu

cocy

tozo

on a

nd P

lasm

odiu

m

Sulf

ado

xin

e +

Pyr

imet

ham

ine

Psi

ttac

ine

0.5

PO

BID

E13

65F

or

sarc

ocy

sto

sis

Sulf

amer

azin

eA

vian

2 g/

LD

rin

kQ

DE

924

Rep

eat

afte

r 2

day

s fo

r co

ccid

iosi

s

Su

lfam

eth

azin

eA

vian

30IM

-SC

NL

E70

4

Sulf

amet

haz

ine

Avi

an0.

2 g/

LD

rin

kQ

DE

704

Rep

eat

afte

r 2

day

s

Sulf

amet

haz

ine

Avi

an50

PO

NL

E70

4

Sulf

amet

haz

ine

Avi

an1

g/L

Dri

nk

NL

E74

1F

or

cocc

idio

sis

plu

s m

ild r

esp

irat

ory

an

d

ente

ric

dis

ease

s

Sulf

amet

haz

ine

Avi

an1

g/L

Dri

nk

NL

E74

1F

or

cocc

idio

sis

plu

s m

ild r

esp

irat

ory

an

d

ente

ric

dis

ease

s

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 79: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 319

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Sulf

amet

haz

ine

Avi

an0.

15 g

/L

Dri

nk

NL

E11

80

Sulf

amet

haz

ine

Avi

an0.

125

g/L

Dri

nk

QD

G57

Use

liquid

fo

rmula

tio

n, w

ait

2 day

s th

en

rep

eat

Sulf

amet

haz

ine

Budge

riga

r7

PO

QD

G57

Wai

t 2

day

s th

en r

epea

t

Sulf

amet

haz

ine

Can

ary

0.15

g/L

Dri

nk

NL

E11

87

Sulf

amet

haz

ine

Can

ary

0.15

g/L

Dri

nk

QD

E69

5

Sulf

amet

haz

ine

Ch

icke

n1

g/L

Dri

nk

QD

E56

412

-day

sla

ugh

ter

wit

hdra

wal

Sulf

amet

haz

ine

Pas

seri

ne

0.15

g/L

Dri

nk

QD

E14

37

Sulf

amet

haz

ine

Pas

seri

ne,

Sm

all

0.15

g/L

Dri

nk

NL

E11

87

Sulf

amet

haz

ine

Pen

guin

, Afr

ican

83-1

25IM

BID

D16

14Sw

itch

to

sulf

adia

zin

e +

sulf

amer

azin

e +

sulf

amet

haz

ine

wh

en a

ble

to

giv

e o

rally

fo

r

mal

aria

Sulf

amet

haz

ine

Pig

eon

2

g/L

D

rin

k Q

D

E

704

Rep

eat

1 to

2 t

imes

at

2-day

inte

rval

s

Sulf

amet

haz

ine

Pig

eon

2

g/L

D

rin

k Q

D

E

704

Rep

eat

afte

r 5

day

s

Sulf

amet

haz

ine

Pig

eon

2 g/

LD

rin

kQ

DE

1240

Wai

t 2

day

s th

en r

epea

t fo

r 3

trea

tmen

t cy

cles

for

cocc

idio

sis,

per

hap

s to

xop

lasm

osi

s

Sulf

amet

haz

ine

Pig

eon

3.33

-6.6

6 g/

LD

rin

kQ

DE

1240

Fo

r co

ccid

iosi

s, p

erh

aps

To

xop

lasm

osi

s

Sulf

amet

haz

ine

Pig

eon

3.33

-6.6

6 g/

LD

rin

kQ

DE

1432

Sulf

amet

haz

ine

Pig

eon

1.1

g/L

Dri

nk

QD

G23

2

Sulf

amet

haz

ine

Pig

eon

1.1

g/L

Dri

nk

QD

G26

0L

oad

ing

do

se 3

75 m

g/L

, tre

at w

ith

B

vita

min

s fo

r 5

day

s th

en r

epea

t

Sulf

amet

haz

ine

Po

ult

ry0.

19-0

.25

g/L

PO

QD

C56

4

Sulf

amet

haz

ine

Po

ult

ry1

g/L

Dri

nk

QD

C56

4

Sulf

amet

haz

ine

Rap

tor

1 g/

LD

rin

kQ

DE

1612

Rep

eat

afte

r 2

day

s

Su

lfan

itra

nC

hic

ken

300

mg/

kg f

oo

dF

eed

QD

E56

4A

dd n

itro

mid

e +

ro

xars

on

e, 5

-day

sla

ugh

ter

wit

hdra

wal

, pro

ph

ylac

tic

Sulf

anit

ran

Po

ult

ry30

0 m

g/kg

fo

od

Fee

dQ

DE

564

Add n

itro

mid

e +

ro

xars

on

e, n

utr

itio

nal

use

,

no

sla

ugh

ter

wit

hdra

wal

Su

lfaq

uin

oxali

ne

An

seri

form

es50

0 m

g/kg

fo

od

Fee

dO

nce

G59

7

Sulf

aquin

oxa

line

Ch

icke

n0.

17 g

/L

Dri

nk

QD

E56

410

-day

sla

ugh

ter

wit

hdra

wal

Sulf

aquin

oxa

line

Duck

0.25

g/kg

Fee

dO

nce

B82

5F

or

Rie

mer

ella

ana

tipe

stife

r in

duck

lings

Sulf

aquin

oxa

line

Lo

ry10

0P

OQ

DG

57

Sulf

aquin

oxa

line

Pig

eon

100

PO

QD

G57

Sulf

aquin

oxa

line

Po

ult

ry0.

397

g/L

Dri

nk

QD

C56

4

Sulf

aquin

oxa

line

Rap

tor

0.03

4 g/

LD

rin

kQ

DE

1612

Rep

eat

afte

r 2

day

s

Sulf

aquin

oxa

line

Turk

ey0.

17 g

/L

Dri

nk

QD

E56

410

-day

sla

ugh

ter

wit

hdra

wal

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 80: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I320

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Su

lfaq

uin

oxali

ne +

Dia

veri

din

e

Avi

an0.

1 g/

kg f

eed

Fee

dQ

DE

1492

Fo

r co

ccid

iosi

s

Sulf

aquin

oxa

line

+

Dia

veri

din

e

Avi

an0.

1 g/

LD

rin

kQ

DE

1492

Fo

r co

ccid

iosi

s

Sulf

aquin

oxa

line

+

Dia

veri

din

e

Avi

an0.

1 g/

kg f

oo

dF

eed

QD

E16

50F

or

cocc

idio

sis

Sulf

aquin

oxa

line

+

Dia

veri

din

e

Avi

an0.

1 g/

LD

rin

kQ

DE

1650

Fo

r co

ccid

iosi

s

Sulf

aquin

oxa

line

+

Dia

veri

din

e

Ch

icke

n0.

5 g/

kg f

eed

Fee

dq4d

E14

79C

occ

idia

l pre

ven

tive

fo

r m

arke

t b

roile

rs

Sulf

aquin

oxa

line

+

Dia

veri

din

e

Ch

icke

n0.

55 g

/kg

fee

dF

eed

QD

E14

79C

occ

idia

l pre

ven

tive

fo

r re

pla

cem

ent/

bre

eder

0 to

8-w

eek

old

bro

ilers

Sulf

aquin

oxa

line

+

Dia

veri

din

e

Ch

icke

n0.

33 g

/kg

fee

dF

eed

QD

E14

79C

occ

idia

l pre

ven

tive

fo

r re

pla

cem

ent/

bre

eder

8 to

12-

wee

k o

ld b

roile

rs

Sulf

aquin

oxa

line

+

Dia

veri

din

e

Po

ult

ry0.

56 g

/L

Dri

nk

QD

E14

79R

epea

t af

ter

3 day

s, c

occ

idio

sis

ther

apy

Sulf

aquin

oxa

line

+

Dia

veri

din

e

Po

ult

ry0.

56 g

/L

Dri

nk

q4d

E14

79C

occ

idia

l pre

ven

tive

Su

lfath

iazo

le S

od

ium

Po

ult

ry1

g/L

Dri

nk

QD

C56

4

Su

lfatr

oxazo

leP

igeo

n50

PO

BID

A56

5A

dd t

rim

eth

op

rim

Su

lfo

nam

ide

Avi

an0.

045

g/L

Dri

nk

QD

E92

4R

epea

t af

ter

2 day

s fo

r co

ccid

iosi

s

Tam

oxif

en

Cit

rate

Gal

lifo

rmes

40N

LN

LB

677

Induce

mo

ltin

g

Tan

nic

Acid

Avi

an3

gT

op

ical

PR

NE

1240

Add a

spir

in +

eth

yl a

lco

ho

l to

pre

par

e 10

0

ml f

or

fun

gal d

erm

atit

is

Tan

nic

Aci

dP

sitt

acin

eT

op

ical

q2w

D14

46A

dd 3

g t

ann

ic a

cid +

3 g

sal

icyl

ic a

cid +

eth

yl a

lco

ho

l fo

r 10

0 m

l of

solu

tio

n f

or

der

mat

om

yco

sis

Tea

Ram

ph

asti

dD

ilute

so

luti

on

Dri

nk

QD

G14

70P

reve

nt

hem

och

rom

ato

sis

by

limit

ing

iro

n

up

take

, no

cit

rus

in d

iet

Terb

inafi

ne

Avi

an10

-15

PO

QD

-BID

E16

68M

ay c

om

bin

e w

ith

itra

con

azo

le f

or

syst

emic

myc

osi

s

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 81: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 321

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Ter

bin

afin

eA

vian

10-1

5P

OQ

D-B

IDG

1338

Fo

r m

yco

sis

Ter

bin

afin

eP

arro

t, G

rey

Co

ngo

1g/L

aqueo

us

Neb

uliz

eT

IDG

1743

Fo

r re

spir

ato

ry a

sper

gillo

sis

Ter

bin

afin

eR

apto

r30

PO

QD

E13

59P

rop

hyl

acti

c

Test

ost

ero

ne

Avi

an10

IMQ

WE

924

Fo

r fe

ath

er d

iso

rder

s

Tes

tost

ero

ne

Avi

an8

IMQ

WE

1473

Tes

tost

ero

ne

Can

ary

2.5

IMQ

WD

1441

Fo

r b

aldn

ess

Tes

tost

ero

ne

Cyp

ion

ate

Psi

ttac

ine

8IM

QW

E12

40U

se w

ith

gre

at c

are

Teta

nu

s A

nti

toxin

Fal

con

, Sak

er25

0 IU

IMQ

DG

822

Lo

adin

g do

se o

f 12

5 IU

eac

h I

V a

nd I

M in

lesi

on

fo

r lo

caliz

ed t

etan

us

Tetr

acycli

ne

Avi

an0.

031-

0.12

4 g/

LD

rin

kN

LE

111

Tet

racy

clin

eA

vian

200-

250

PO

BID

E11

1

Tet

racy

clin

eA

vian

1.25

ml/

LD

rin

kN

LE

741

Tet

racy

clin

eG

allif

orm

es30

-60

Dri

nk

QD

E70

4

Tet

racy

clin

eP

hea

san

t0.

04-0

.12

g/L

Fee

dQ

DG

678

Tet

racy

clin

eP

hea

san

t55

-110

mg/

kg f

oo

dF

eed

QD

G67

8

Tet

racy

clin

eP

igeo

n22

0 m

g/kg

fo

od

Dri

nk

QD

E70

450

%, 2

.5 g

per

tea

spo

on

Tet

racy

clin

eP

igeo

n0.

549

g/L

Dri

nk

QD

E12

40F

or

chla

myd

op

hilo

sis

Tet

racy

clin

eP

igeo

n50

mg

TD

PO

QD

G47

Rem

ove

gri

t fr

om

die

t duri

ng

trea

tmen

t

Tet

racy

clin

eP

oult

ry60

Dri

nk

QD

C70

5

Tet

racy

clin

eP

sitt

acin

e50

PO

TID

E56

5

Tet

racy

clin

eP

sitt

acin

e1

g/L

so

ft f

oo

dF

eed

On

ceE

763

May

add lo

ng-

last

ing

oxy

tetr

acyc

line

Tet

racy

clin

eQ

uai

l22

0 m

g/kg

fo

od

Fee

dQ

DG

678

Tet

racy

clin

eQ

uai

l55

-110

mg/

kg f

oo

dF

eed

QD

G67

8

Th

iab

en

dazo

leA

nse

rifo

rmes

550

NL

NL

G13

25F

or

tho

rny

hea

ded

wo

rms

Th

iab

endaz

ole

Avi

an10

0P

OQ

DE

111

Fo

r Syn

gam

us

Th

iab

endaz

ole

Avi

an25

0-50

0P

Oq2w

E11

1F

or

asca

rids

Th

iab

endaz

ole

Avi

an20

0P

Oq10

dE

924

Fo

r Syn

gam

us, A

mid

osto

mum

Th

iab

endaz

ole

Avi

an10

0P

OQ

DG

1309

Fo

r Syn

gam

us tra

chei

Th

iab

endaz

ole

Avi

an25

0-50

0P

Oq10

dG

1309

Fo

r as

cari

ds

Th

iab

endaz

ole

Ch

icke

n5

g/kg

fo

od

Fee

dQ

DG

1325

Fo

r as

cari

ds,

Cap

illar

ia a

nd g

apew

orm

s

Th

iab

endaz

ole

Ch

icke

n44

PO

On

ceG

1325

Fo

r A

scar

ids,

Cap

illar

ia a

nd g

apew

orm

s

Th

iab

endaz

ole

Cra

ne

100

PO

QW

-q2w

E13

61F

or

inte

stin

al s

tro

ngy

les,

asc

arid

s

Th

iab

endaz

ole

Fal

con

100

PO

On

ceG

1325

Fo

r as

cari

ds,

Cap

illar

ia a

nd g

apew

orm

s

Th

iab

endaz

ole

Pig

eon

44P

OO

nce

G13

25F

or

Asc

arid

s, C

apill

aria

an

d g

apew

orm

s

Th

iab

endaz

ole

Rap

tor

100-

200

PO

BID

E14

00C

on

tro

l of

nem

ato

des

, may

inte

rfer

e w

ith

egg

layi

ng

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 82: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I322

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Th

iab

endaz

ole

Rat

ite

50N

LN

LG

418

Th

iab

endaz

ole

Turk

ey44

PO

On

ceG

1325

Fo

r as

cari

ds,

Cap

illar

ia a

nd g

apew

orm

s

Th

iam

ine

An

seri

form

es25

mg/

kg f

ish

Fee

dO

nce

E11

90

Th

iam

ine

An

seri

form

es25

Fee

dQ

DG

46Su

pp

lem

ent

for

fish

eat

ers

Th

iam

ine

Avi

an1-

2IM

-PO

On

ceE

1650

Fo

r h

ypo

vita

min

osi

s B1

Th

iam

ine

Bir

d, P

isci

voro

us

0.2

g/kg

fis

hF

eed

QD

E15

54F

or

fish

die

t

Th

iam

ine

Bir

d, P

isci

voro

us

1-2

PO

QD

E15

54F

or

fish

die

t

Th

iam

ine

Cra

ne

1-2

PO

QD

E11

1

Th

iam

ine

Duck

100

µg/

LD

rin

kQ

DE

1358

Fo

r st

arga

zin

g an

d w

eigh

t lo

ss in

duck

lings

Th

iam

ine

Eag

le, B

ald

1-3

NL

QW

E11

88If

eat

ing

fro

zen

fis

h

Th

iam

ine

Osp

rey

1-3

NL

QW

E11

88If

eat

ing

fro

zen

fis

h

Th

iam

ine

Rap

tor

1-2

PO

QD

E11

1

Th

iam

ine

Rap

tor

2P

OQ

WE

1068

Wh

ile f

eedin

g fr

oze

n f

ish

Th

iam

ine

Rap

tor

0.2-

0.25

g/kg

fis

hF

eed

QD

E11

32F

or

fish

die

ts

Th

iam

ine

Rap

tor

25IM

NL

E14

33

Th

iam

ine

Rap

tor

1IM

NL

E14

63

Th

iop

en

tal

So

diu

mC

hic

ken

16.2

IMP

RN

B10

80A

dd p

ento

bar

bit

al s

odiu

m

Th

iop

enta

l So

diu

mC

hic

ken

10-1

2.5

NL

PR

NB

1126

Th

iop

enta

l So

diu

mD

uck

, Mal

lard

54P

OP

RN

B10

95

Th

iop

enta

l So

diu

m

Turk

ey

16.2

IM

P

RN

B

10

80

Add p

ento

bar

bit

al s

odiu

m

Th

yro

id S

tim

ula

tin

g

Ho

rmo

ne

Am

azo

n P

arro

t1

IU T

DIM

On

ceB

88

Th

yro

id S

tim

ula

tin

g

Ho

rmo

ne

Co

ckat

iel

0.1

U T

DIM

On

ceB

88

Th

yro

id S

tim

ula

tin

g

Ho

rmo

ne

Par

rot,

Gre

y1

U T

DIM

NL

B53

3

Th

yro

id S

tim

ula

tin

g

Ho

rmo

ne

Pig

eon

1 U

TD

IMO

nce

B88

Th

yro

id S

tim

ula

tin

g

Ho

rmo

ne

Psi

ttac

ine

1-2

IU/kg

IMN

LE

1473

Tia

mu

lin

Avi

an25

-50

PO

QD

E56

5

Tia

mulin

Avi

an1.

08 m

g/kc

alP

OQ

DE

1180

Tia

mulin

Avi

an25

PO

QD

E14

92F

or

myc

op

lasm

osi

s

Tia

mulin

Ch

icke

n0.

25 g

/L

Dri

nk

NL

B85

7F

or

Myc

opla

sma

Tia

mulin

Gal

lifo

rmes

25-3

0D

rin

kQ

DE

704

Use

1/2

stre

ngt

h f

or

pro

ph

ylax

is

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 83: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 323

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Tia

mulin

Pig

eon

0.22

5 g/

LD

rin

kQ

DE

704

Tic

arc

illi

nA

vian

150-

200

IM-I

VT

ID-Q

IDE

111

Tic

arci

llin

Avi

an5.

1 m

g/kc

alIM

-IV

q2-

4hE

1180

Syn

ergi

stic

wit

h a

min

ogl

yco

sides

Tic

arci

llin

Rap

tors

200

IMT

IDE

1027

Tic

arci

llin

Pig

eon

200

IM-I

VB

ID-T

IDG

590

Tic

arci

llin

Psi

ttac

ine

200

IMB

ID-Q

IDE

565

Til

eta

min

e +

Zo

lazep

am

Alb

atro

ss2

IVP

RN

E16

17In

duct

ion

fo

r ga

s an

esth

esia

Tile

tam

ine

+ Z

ola

zep

amA

vian

5-10

IMP

RN

E11

81, 1

231

Go

od im

mo

bili

zati

on

Tile

tam

ine

+ Z

ola

zep

amA

vian

2IV

PR

NE

1617

Induct

ion

fo

r ga

s an

esth

esia

Tile

tam

ine

+ Z

ola

zep

amB

udge

riga

r15

-20

IMP

RN

E24

3

Tile

tam

ine

+ Z

ola

zep

amB

udge

riga

r20

-22

IMP

RN

G51

8

Tile

tam

ine

+ Z

ola

zep

amC

asso

war

y2-

3IV

PR

NE

1533

Tile

tam

ine

+ Z

ola

zep

amC

hic

ken

30IM

On

ceB

1737

Tile

tam

ine

+ Z

ola

zep

amC

ock

ato

o, G

Sulf

ur-

cres

ted

2.64

-25.

2IM

PR

NG

518

Tile

tam

ine

+ Z

ola

zep

amD

ove

, Rin

g-n

ecke

d50

-75

IMP

RN

B13

93

Tile

tam

ine

+ Z

ola

zep

amD

uck

5-10

IMP

RN

E24

3

Tile

tam

ine

+ Z

ola

zep

amE

agle

, Bal

d15

NL

PR

ND

1401

Sup

ple

men

t w

ith

15

mg/

kg k

etam

ine

Tile

tam

ine

+ Z

ola

zep

amE

gret

, Cat

tle

2IV

PR

NE

1617

Induct

ion

fo

r ga

s an

esth

esia

Tile

tam

ine

+ Z

ola

zep

amE

mu

2-3

IVP

RN

E15

33

Tile

tam

ine

+ Z

ola

zep

amE

mu

5-10

IMP

RN

E16

17In

duct

ion

fo

r ga

s an

esth

esia

Tile

tam

ine

+ Z

ola

zep

amF

lam

ingo

22IM

PR

NG

518

Tile

tam

ine

+ Z

ola

zep

amF

lam

ingo

, Ch

ilean

6.6

IMP

RN

B13

93

Tile

tam

ine

+ Z

ola

zep

amG

ann

et2

IVP

RN

E16

17In

duct

ion

fo

r ga

s an

esth

esia

Tile

tam

ine

+ Z

ola

zep

amG

oo

se, L

esse

r M

agel

lan

6.6-

8.8

IMP

RN

B13

93

Tile

tam

ine

+ Z

ola

zep

amG

oo

se, W

hit

e-fr

on

ted

2.7

IMP

RN

B13

93

Tile

tam

ine

+ Z

ola

zep

amH

awk

15N

LP

RN

D14

01M

ay c

ause

sal

ivat

ion

an

d p

oo

r

imm

ob

iliza

tio

n

Tile

tam

ine

+ Z

ola

zep

amH

orn

bill

, Rh

ino

cero

s28

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PR

NG

518

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tam

ine

+ Z

ola

zep

amIb

is, W

oo

d11

IMP

RN

G51

8

Tile

tam

ine

+ Z

ola

zep

amJa

bir

us

2IV

PR

NE

1617

Induct

ion

fo

r ga

s an

esth

esia

Tile

tam

ine

+ Z

ola

zep

amM

acaw

, Sca

rlet

4.4-

11IM

PR

NB

1393

Tile

tam

ine

+ Z

ola

zep

amO

spre

y9.

26-1

7.6

IMP

RN

G51

8

Tile

tam

ine

+ Z

ola

zep

amO

stri

ch5-

20IM

PR

NB

522

Ch

ick

do

sage

Tile

tam

ine

+ Z

ola

zep

amO

stri

ch4-

5IM

PR

NB

1393

Tile

tam

ine

+ Z

ola

zep

amO

stri

ch5-

10IM

PR

NG

481

Add d

iaze

pam

just

pri

or

to r

eco

very

fo

r

cap

tive

an

imal

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 84: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I324

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Tile

tam

ine

+ Z

ola

zep

amO

wl

10N

LP

RN

D14

01Su

pp

lem

ent

wit

h 1

0 m

g/kg

ket

amin

e P

RN

Tile

tam

ine

+ Z

ola

zep

amP

arak

eet,

Rin

g-n

ecke

d26

IMP

RN

B13

93

Tile

tam

ine

+ Z

ola

zep

amP

arro

t, P

atag

on

ian

11IM

PR

NG

518

Tile

tam

ine

+ Z

ola

zep

amP

artr

idge

, Cre

sted

Wo

od

10IM

PR

NB

1393

Tile

tam

ine

+ Z

ola

zep

amP

ea F

ow

l11

.3IM

PR

NG

518

Tile

tam

ine

+ Z

ola

zep

amP

elic

an2

IVP

RN

E16

17In

duct

ion

fo

r ga

s an

esth

esia

Tile

tam

ine

+ Z

ola

zep

amP

hea

san

t, G

old

en16

.6IM

PR

NB

1393

Tile

tam

ine

+ Z

ola

zep

amP

igeo

n40

-60

IMP

RN

B13

93

Tile

tam

ine

+ Z

ola

zep

amP

igeo

n30

-60

IMO

nce

B17

37

Tile

tam

ine

+ Z

ola

zep

amP

love

r17

.6IM

PR

NG

518

Tile

tam

ine

+ Z

ola

zep

amP

sitt

acin

e10

NL

PR

ND

1401

Tile

tam

ine

+ Z

ola

zep

amP

sitt

acin

e5-

10IM

PR

NE

1240

Pro

vides

go

od im

mo

bili

zati

on

Tile

tam

ine

+ Z

ola

zep

amR

apto

r10

-20

IMN

LD

1400

Tile

tam

ine

+ Z

ola

zep

amR

atit

e2-

5IM

PR

NG

418

Sup

ple

men

t w

ith

ket

amin

e P

RN

Tile

tam

ine

+ Z

ola

zep

amSt

ork

2-5

IMN

LE

243

Sedat

ion

Tile

tam

ine

+ Z

ola

zep

amSw

an, B

lack

6.6

NL

PR

ND

1401

Sup

ple

men

t w

ith

6.6

mg/

kg k

etam

ine

PR

N

Tile

tam

ine

+ Z

ola

zep

amT

eal,

Blu

e-w

inge

d22

-35

IMP

RN

B13

93

Tile

tam

ine

+ Z

ola

zep

amW

oo

dco

ck44

IMP

RN

G51

8

Til

mic

osi

nC

hic

ken

0.07

5 g/

LD

rin

kN

LA

804

Fo

r M

ycop

lasm

a

Tilm

ico

sin

Ch

icke

n0.

25-0

.5 g

/L

Dri

nk

NL

B76

8F

or

Myc

opla

sma

Tilm

ico

sin

Ch

icke

n0.

1-0.

3 g/

LD

rin

kN

LB

798

Tin

idaz

ole

Avi

an50

PO

NL

G57

To

bra

mycin

Avi

an10

IMB

ID-T

IDE

565

To

bra

myc

inA

vian

5IM

BID

-TID

E70

4

To

bra

myc

inA

vian

5 g/

LN

ebuliz

eT

IDE

741

Fo

r si

nusi

tis

or

airs

accu

litis

To

bra

myc

inC

ran

e2.

5-5

IMB

IDE

1473

To

bra

myc

inP

arro

t, G

rey

10IM

TID

E74

1P

oss

ible

po

lyuri

a

To

bra

myc

inP

hea

san

t2.

5-5

IMB

IDE

1473

To

bra

myc

inP

sitt

acin

e2.

5-5

IMB

IDE

111

To

bra

myc

inP

sitt

acin

e5-

10IT

QD

E74

1A

dd c

arb

enic

illin

fo

r p

neu

mo

nia

To

bra

myc

inR

apto

r2.

5-5

IMB

IDE

1240

Fo

r re

sist

ant

Pse

udom

onas

To

bra

myc

inR

apto

r5-

10IM

-IV

BID

E14

00L

ess

nep

hro

toxi

c th

an o

ther

am

ino

glyc

osi

des

To

bra

myc

inR

apto

r10

IMB

IDG

234

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 85: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 325

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

To

lazo

lin

e H

Cl

Avi

an15

IVP

RN

E13

20R

ever

se x

ylaz

ine

+det

om

idin

e +

med

eto

mid

ine

To

lazo

line

HC

lO

stri

ch1

IVP

RN

G48

1R

ever

se x

ylaz

ine

To

lazo

line

HC

lR

apto

r15

IVP

RN

G20

1

To

ltra

zu

ril

An

seri

form

es0.

0125

g/L

Dri

nk

QD

D11

50F

or

cocc

idio

sis

To

ltra

zuri

lA

vian

7P

OQ

DD

1221

An

tip

roto

zoal

To

ltra

zuri

lA

vian

0.15

g/L

Dri

nk

NL

E11

80

To

ltra

zuri

lA

vian

0.09

0 m

g/kc

alP

OQ

DE

1180

Co

ccid

iost

atic

To

ltra

zuri

lA

vian

7-10

PO

QD

E15

54F

or

cocc

idio

sis

To

ltra

zuri

lC

hic

ken

6P

OQ

DE

1479

May

rep

eat

afte

r 5

day

s fo

r tr

eatm

ent

and

con

tro

l of

Eim

eria

co

ccid

iosi

s

To

ltra

zuri

lC

hic

ken

25P

OQ

DG

564

To

ltra

zuri

lF

alco

n25

PO

QW

B11

34F

or

Car

yosp

ora

infe

stat

ion

To

ltra

zuri

lK

estr

el, E

uro

pea

n25

PO

QD

B11

31F

or

Car

yosp

ora

infe

ctio

n

To

ltra

zuri

lK

iwi

25P

OO

nce

G12

23F

or

cocc

idio

sis

To

ltra

zuri

lM

ynah

, Bal

i12

.5P

OQ

DD

1438

Fo

r co

ccid

iosi

s

To

ltra

zuri

lT

urk

ey0.

025

g/L

Dri

nk

QD

B10

25

Tri

bro

mo

eth

an

ol

Bir

d, S

eed-e

ater

2 g/

kg g

rain

Fee

dO

nce

E4

Add c

hlo

ralo

se

Tri

bro

mo

eth

ano

lB

ird, S

eed-e

ater

0.02

5 g/

LF

eed

On

ceE

4

Tri

bro

mo

eth

ano

lB

oo

by

125

PO

PR

NB

1081

Add a

myl

ene

hyd

rate

Tri

bro

mo

eth

ano

lC

orm

ora

nt

125

PO

PR

NB

1081

Add a

myl

ene

hyd

rate

Tri

bro

mo

eth

ano

lD

uck

, Mal

lard

100-

158

PO

PR

NB

1095

Tri

bro

mo

eth

ano

lF

riga

teb

ird, M

agn

ific

ent

125

PO

PR

NB

1081

Add a

myl

ene

hyd

rate

Tri

bro

mo

eth

ano

lT

urk

ey40

-44

g/L

bai

tF

eed

On

ceG

1767

Co

rn is

usu

al b

ait

Tri

ch

lorf

on

Rap

tors

1.5

g/L

(0.

15%

)T

op

ical

NL

G14

08Sp

ray

for

mit

es

Tri

cid

eA

vian

5 g/

LT

op

ical

NL

G12

78Sp

ray

on

wo

un

ds

and d

erm

atit

is

Tri

cide

Avi

an5

g/L

Flu

shN

LG

1278

Sin

us

flush

, add a

nti

bio

tic

to s

olu

tio

n,

po

ten

tiat

es a

nti

bio

tics

am

ikac

in, n

eom

ycin

,

enro

flo

xaci

n

Tri

meth

op

rim

+ S

ulf

aA

nse

rifo

rmes

0.04

8 g/

LD

rin

kQ

DE

1240

Fo

r n

eph

riti

s, s

epti

cem

ia, h

epat

itis

. Fo

r E

.

coli,

Pas

teur

ella

, Pro

teus

, Sal

mon

ella

, L

iste

ria

Tri

met

ho

pri

m +

Sulf

aA

vian

25IM

BID

E14

34

Tri

met

ho

pri

m +

Sulf

aA

vian

50IM

QD

E14

34

Tri

met

ho

pri

m +

Sulf

aA

vian

30-6

0P

O-S

CB

IDE

1483

Em

erge

ncy

th

erap

y

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 86: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I326

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Tri

met

ho

pri

m +

Sulf

aA

vian

50-1

00P

OB

IDG

1319

Tri

met

ho

pri

m +

Sulf

aA

vian

0.15

-0.4

g/L

Dri

nk

NL

E11

80D

osa

ge b

ased

on

tri

met

ho

pri

m

Tri

met

ho

pri

m +

Sulf

aA

vian

20-5

0P

OB

IDE

1431

Fo

r co

ccid

iosi

s

Tri

met

ho

pri

m +

Sulf

aA

vian

1 g/

LD

rin

kQ

DE

1431

Fo

r co

ccid

iosi

s

Tri

met

ho

pri

m +

Sulf

aA

vian

10IM

BID

E14

31F

or

cocc

idio

sis

Tri

met

ho

pri

m +

Sulf

aB

ust

ard

8-30

IMB

IDE

1240

Fo

r n

eph

riti

s, s

epti

cem

ia, h

epat

itis

. Fo

r E

.

coli,

Pas

teur

ella

, Pro

teus

, Sal

mon

ella

, Lis

teri

a

Tri

met

ho

pri

m +

Sulf

aC

anar

y0.

05-0

.1 g

/L

Dri

nk

QD

E69

5D

osa

ge b

ased

on

tri

met

ho

pri

m

Tri

met

ho

pri

m +

Sulf

aC

anar

y0.

1 g/

kg f

oo

dF

eed

QD

E69

5D

osa

ge b

ased

on

tri

met

ho

pri

m

Tri

met

ho

pri

m +

Sulf

aC

anar

y0.

2 g/

kg f

oo

dF

eed

On

ceE

1187

Do

sage

bas

ed o

n t

rim

eth

op

rim

on

ly

Tri

met

ho

pri

m +

Sulf

aC

anar

y0.

15-0

.4 g

/L

Dri

nk

NL

E11

87D

osa

ge b

ased

on

tri

met

ho

pri

m o

nly

Tri

met

ho

pri

m +

Sulf

adia

zin

e

Ch

icke

n46

-62

Dri

nk

QD

A10

23

Tri

met

ho

pri

m +

Sulf

ach

lorp

yrid

azin

e

Go

ose

0.3-

0.7

g/kg

Fee

dO

nce

A77

6F

or

Pas

teur

ella

mul

tocida

,tr

imet

ho

pri

m t

o s

ulf

a

rati

o 1

:5

Tri

met

ho

pri

m +

Sulf

aO

stri

ch15

IMQ

DG

401

Tri

met

ho

pri

m +

Sulf

aP

asse

rin

e0.

2 g/

LD

rin

kQ

DE

1437

Do

sage

bas

ed o

n t

rim

eth

op

rim

, add d

rug

to

foo

d a

t th

e sa

me

tim

e

Tri

met

ho

pri

m +

Sulf

aP

asse

rin

e0.

2 g/

kgF

eed

QD

E14

37D

osa

ge b

ased

on

tri

met

ho

pri

m, a

dd d

rug

to

dri

nk

at t

he

sam

e ti

me

Tri

met

ho

pri

m +

Sulf

aP

engu

in, A

fric

an11

0P

OB

IDG

128

Tri

met

ho

pri

m +

Sulf

aP

igeo

n12

0P

OQ

DE

704

Tri

met

ho

pri

m +

Sulf

aP

oult

ry55

PO

BID

G58

5

Tri

met

ho

pri

m +

Sulf

aP

oult

ry0.

3-0.

5 g/

LD

rin

kQ

DG

585

Tri

met

ho

pri

m +

Sulf

aP

sitt

acin

e20

PO

BID

-TID

E12

40F

or

nep

hri

tis,

sep

tice

mia

, hep

atit

is. F

or

E.

coli,

Pas

teur

ella

, Pro

teus

, Sal

mon

ella

, Lis

teri

a

Tri

met

ho

pri

m +

Sulf

aP

sitt

acin

e8

IMB

IDE

1240

Fo

r n

eph

riti

s, s

epti

cem

ia, h

epat

itis

. Fo

r E

.

coli,

Pas

teur

ella

, Pro

teus

, Sal

mon

ella

, Lis

teri

a

Tri

met

ho

pri

m +

Sulf

aP

sitt

acin

e16

-100

PO

BID

-TID

E17

56U

se lo

wer

do

sage

fo

r b

irds

un

der

300

g f

or

bac

teri

al n

eph

riti

s

Tri

met

ho

pri

m +

Sulf

aP

sitt

acin

e52

.8IM

QD

-BID

G13

09F

or

resp

irat

ory

an

d e

nte

ric

infe

ctio

ns

Tri

met

ho

pri

m +

Sulf

aR

apto

r30

SCB

IDE

1240

Fo

r n

eph

riti

s, s

epti

cem

ia, h

epat

itis

. F

or E

.

coli,

Pas

teur

ella

, Pro

teus

, Sal

mon

ella

, Lis

teri

a

Tri

met

ho

pri

m +

Sulf

aR

apto

r20

-50

PO

BID

E14

33D

o n

ot

use

on

deh

ydra

ted b

irds

Tri

met

ho

pri

m +

Sulf

aR

apto

r60

PO

BID

E14

00F

or

cocc

idio

sis,

rep

eat

afte

r 2

day

s

Tri

met

ho

pri

m +

Sulf

aR

apto

r17

.5P

OQ

DG

94Ju

ven

ile d

osa

ge

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 87: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 327

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Tri

met

ho

pri

m +

Sulf

aR

apto

r50

IMB

IDG

234

Tri

met

ho

pri

m +

Sulf

aR

atit

e30

-50

IMB

IDG

1308

Fo

r to

xop

lasm

osi

s

Tri

met

ho

pri

m +

Sulf

amet

ho

xazo

le

Pig

eon

60P

OQ

DA

968

Tri

met

ho

pri

m +

Sulf

amet

ho

xazo

le

Psi

ttac

ine

16-2

4P

OB

ID-T

IDA

1473

Tri

met

ho

pri

m +

Sulf

amet

ho

xazo

le

Psi

ttac

ine

8IM

BID

A14

73

Tri

met

ho

pri

m +

Sulf

atro

xazo

le

Pig

eon

60P

OB

IDA

968

Tu

bo

cu

rari

ne C

lR

apto

r3

g/L

Op

hth

alm

icN

LE

111

Eve

ry 5

min

ute

s

Tylo

sin

An

seri

form

es20

-30

IMT

IDD

1150

Fo

r m

yco

pla

smo

sis

Tyl

osi

nA

nse

rifo

rmes

20P

OT

IDD

1150

Fo

r m

yco

pla

smo

sis

Tyl

osi

nA

nse

rifo

rmes

10 g

/L

Flu

shQ

DD

1150

Fo

r m

yco

pla

smo

sis,

use

10

ml p

er b

ird

Tyl

osi

nA

vian

0.75

g/L

Dri

nk

NL

E11

80

Tyl

osi

nA

vian

0.86

mg/

kcal

IMT

ID-Q

IDE

1180

Tyl

osi

nA

vian

1.08

mg/

kcal

PO

QD

E11

80

Tyl

osi

nA

vian

10 g

/L

sal

ine

Flu

shB

IDE

1183

Nas

al o

r si

nus

Tyl

osi

nA

vian

10 g

/L

sal

ine

Neb

uliz

eB

IDE

1185

10 t

o 6

0 m

inute

s

Tyl

osi

nA

vian

15IM

TID

E12

40F

or

bir

ds

> 1

kg

for

up

per

res

pir

ato

ry

infe

ctio

n f

or

Myc

opla

sma,

Pas

teur

ella

,

Chl

amyd

ophi

la

Tyl

osi

nA

vian

10IM

BID

E16

17F

or

Myc

op

lasm

a

Tyl

osi

nA

vian

10 g

/L

Neb

uliz

eT

ID-Q

IDE

1650

Add d

imet

hyl

sulf

oxi

de,

adju

nct

to

par

ente

ral

ther

apy

for

air

sacc

ulit

is

Tyl

osi

nA

vian

10-4

0IM

BID

E16

50M

ay u

se w

ith

lin

com

ycin

+ s

pec

tin

om

ycin

for

myc

op

lasm

osi

s

Tyl

osi

nB

ird, A

quat

ic10

IMB

IDE

1503

Fo

r M

ycop

lasm

a

Tyl

osi

nB

ust

ard, H

oub

ara

20IM

TID

G93

2F

or

Myc

opla

sma

Tyl

osi

nC

anar

y0.

25-0

.4 g

/L

Dri

nk

QD

E69

5

Tyl

osi

nC

anar

y0.

4 g/

kg f

oo

dF

eed

On

ceE

1187

Tyl

osi

nC

hic

ken

0.5

g/L

Dri

nk

NL

A83

8F

or

Myc

opla

sma

galli

sept

icum

, les

s ef

fect

ive

than

dan

ofl

oxa

cin

Tyl

osi

nC

hic

ken

0.25

g/L

Dri

nk

QD

B10

16A

dd c

olis

tin

fo

r ch

ron

ic r

esp

irat

ory

dis

ease

wit

h E

. co

li

Tyl

osi

nC

ock

atie

lM

ix p

ow

der

1:1

0O

ph

thal

mic

BID

-TID

E11

1M

ix p

ow

der

wit

h s

teri

le w

ater

1 t

o 1

0

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 88: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I328

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Tyl

osi

nC

ock

atie

l1:

10 d

iluti

on

wat

erT

op

ical

QD

-TID

E74

1E

ye s

pra

y, p

ow

der

250

g/8.

8 o

z,

con

jun

ctiv

itis

, may

use

wit

h t

ylo

sin

in w

ater

Tyl

osi

nC

ran

e15

SCT

IDA

596

Tyl

osi

nE

mu

15-2

5IM

TID

-QID

E14

73

Tyl

osi

nF

alco

n30

IMT

IDE

1027

Fo

r M

ycop

lasm

a

Tyl

osi

nF

inch

0.4

g/kg

fo

od

Fee

dQ

DE

1572

Tyl

osi

nF

inch

0.25

-0.4

g/L

Dri

nk

QD

E15

72

Tyl

osi

nF

inch

, Ho

use

1 g/

LD

rin

kQ

DD

1439

Add c

ipro

flo

xaci

n f

or

myc

op

lasm

osi

s

Tyl

osi

nF

inch

, Ho

use

0.3

g/L

Dri

nk

QD

D14

39P

reve

nti

ve f

or

myc

op

lasm

osi

s

Tyl

osi

nO

stri

ch11

.4P

OT

IDG

467

Tyl

osi

nP

asse

rin

e0.

25-0

.4 g

/L

Dri

nk

QD

E14

37A

dd d

rug

to f

oo

d a

t th

e sa

me

tim

e

Tyl

osi

nP

asse

rin

e, S

mal

l0.

25-0

.4 g

/L

Dri

nk

NL

E11

87

Tyl

osi

nP

igeo

n25

IMQ

IDA

847

Tyl

osi

nP

igeo

n15

-25

IMT

ID-Q

IDE

111

Tyl

osi

nP

igeo

n50

PO

QD

E70

4

Tyl

osi

nP

igeo

n0.

5 g/

LD

rin

kQ

DE

704

Tyl

osi

nP

igeo

n15

-25

IMT

ID-Q

IDE

1473

Tyl

osi

nP

sitt

acin

eM

ix p

ow

der

1:1

0O

ph

thal

mic

BID

-TID

E11

1M

ix p

ow

der

wit

h s

teri

le w

ater

1 t

o 1

0

Tyl

osi

nP

sitt

acin

e40

IMN

LE

763

Init

ial M

ycop

lasm

a th

erap

y, u

sed in

com

bin

atio

n w

ith

am

ino

glyc

osi

des

Tyl

osi

nP

sitt

acin

e20

-40

IMT

IDE

1240

Tyl

osi

nQ

uai

l15

-25

IMT

ID-Q

IDE

1473

Tyl

osi

nR

apto

r15

IMQ

DD

1612

Fo

r ch

ron

ic a

ir s

accu

litis

Tyl

osi

nR

apto

r20

IMB

IDG

234

Tyl

osi

nR

hea

12.5

mg

TD

Par

ente

ral

On

ceG

582

Into

dis

ten

ded

sin

us

Tyl

osi

nR

hea

50 m

g T

DSC

QD

G58

2A

dd p

enic

illin

G b

enza

thin

e

Ura

te O

xid

ase

Haw

k, R

ed-t

aile

d10

0-20

0 K

IU/kg

NL

NL

A17

61U

rico

lyti

c

Ura

te O

xidas

eP

igeo

n20

-600

KIU

/kg

NL

NL

A17

61U

rico

lyti

c

Valn

em

uli

nC

hic

ken

0.5

g/L

Dri

nk

QD

B87

3F

or

Myc

opla

sma

Vaso

tocin

, A

rgin

ine

Spar

row

, Ho

use

0.00

04-0

.001

6IV

PR

NB

1759

Do

sage

is d

osa

ge p

er m

inute

, use

d f

or

anti

diu

resi

s

Vecu

ron

ium

Bro

mid

eA

vian

1 dro

p 4

mg/

ml s

oln

Op

hth

alm

icq15

min

E12

33

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 89: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 329

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Vec

uro

niu

m B

rom

ide

Co

ckat

oo

0.8

g/L

Op

hth

alm

icN

LG

218

Vin

cri

stin

e S

ulf

ate

Avi

an0.

75 m

g/m

2 surf

ace

IO

QW

E

14

70

Fo

r ly

mp

ho

sarc

om

a -

Ch

eck

cure

nt

liter

ature

Vin

eg

ar,

Ap

ple

Cid

er

Avi

an15

ml/

LD

rin

kQ

DD

1330

Fo

r lo

w-g

rade

can

did

iasi

s

Vin

egar

, Ap

ple

Cid

erA

vian

60-1

20 m

l/L

Dri

nk

QD

E12

05F

or

dys

bio

sis,

Clo

stri

dium

, GI

trac

t b

acte

rio

sis

Vin

egar

, Ap

ple

Cid

erA

vian

60-1

20 m

l/L

Dri

nk

QD

E14

87F

or

dys

bio

sis,

can

did

iasi

s, c

hro

nic

bac

teri

al

dia

rrh

ea, G

ram

neg

ativ

e in

fect

ion

s, f

oul s

mel

l

fece

s

Vir

gin

iam

ycin

Po

ult

ry22

mg/

kg f

oo

dF

eed

QD

C56

4

Vit

am

in A

Am

azo

n, R

ed L

ore

d20

KIU

/kg

IMO

nce

G70

0

Vit

amin

AA

vian

< 5

0 K

IU/kg

NL

On

ceE

1481

Fo

r cl

inic

al d

efic

ien

cy

Vit

amin

AR

apto

r<

20

KIU

/kg

IMQ

WE

1400

Fo

r h

ypo

vita

min

osi

s A

an

d e

pit

hel

ial

rege

ner

atio

n (

bum

ble

foo

t)

Vit

am

in B

Co

mp

lex

Am

azo

n, Y

ello

w-n

aped

1P

aren

tera

lN

LG

1697

Do

sage

bas

ed o

n t

hia

min

e

Vit

amin

B C

om

ple

xA

vian

1-3

IMQ

WE

1470

Aft

er h

emo

rrh

age

wit

h li

ver

dis

ease

Vit

amin

B C

om

ple

xA

vian

10IM

NL

E16

50D

osa

ge b

ased

on

th

iam

ine

for

emer

gen

cy

care

Vit

amin

B C

om

ple

xB

ird, A

quat

ic10

-30

IM-S

CQ

WE

1503

Fo

r deb

ilita

tio

n, a

nem

ia, a

pp

etit

e st

imula

nt,

neu

rolo

gica

l dis

ord

ers

Vit

amin

B C

om

ple

xH

awk,

Red

-tai

led

10P

OO

nce

G16

44D

osa

ge b

ased

on

th

iam

ine

for

deb

ilita

tio

n

Vit

amin

B C

om

ple

xP

sitt

acin

e10

-30

(th

iam

ine

do

se)

IMq2d

E12

40D

osa

ge b

ased

on

th

iam

ine,

neu

rom

usc

ula

r

dis

ease

, hep

atic

dis

ord

ers,

th

iam

ine-

resp

on

sive

sei

zure

s

Vit

amin

B C

om

ple

xR

apto

r10

-30

IMQ

WE

1240

Do

sage

bas

ed o

n t

hia

min

e, s

tim

ula

te a

pp

etit

e

Vit

am

in D

Avi

an6.

6 K

IU/kg

IMO

nce

G58

Add c

alci

um

glu

con

ate

+ o

xyto

cin

Vit

am

in E

Avi

an40

IM-P

ON

LE

924

An

tio

xidan

t, m

etal

to

xici

ty

Vit

amin

EA

vian

0.05

-0.1

Par

ente

ral

QW

E16

50F

or

hyp

ovi

tam

ino

sis

E

Vit

amin

EB

ird, A

quat

ic0.

1 K

IU/kg

oil

fish

Fee

dO

nce

E14

78

Vit

amin

EO

stri

ch0.

2-0.

3 K

IU/kg

IMN

LG

93Ju

ven

ile d

ose

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 90: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I330

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Vit

am

in E

+ S

ele

niu

m

Am

azo

n, R

ed L

ore

d

1 m

g Se

, 25

mg

E

IM

On

ce

G

700

Vit

amin

E +

Sel

eniu

mA

vian

0.05

-0.1

IMq2w

E11

1

Vit

amin

E +

Sel

eniu

mO

stri

ch4-

100

KIU

TD

IMQ

MG

401

Vit

amin

E +

Sel

eniu

mR

apto

rSC

q3d

E12

400.

05 m

g se

len

ium

+ 3

.4 I

U v

itam

in E

to

tal

do

se f

or

musc

ula

r w

eakn

ess,

cap

ture

myo

pat

hy,

def

icie

ncy

Vit

am

in K

Am

azo

n, Y

ello

w-n

aped

0.2

Par

ente

ral

NL

G16

97

Vit

amin

KA

vian

0.2-

2.2

IMq4-

8hG

87F

ollo

w w

ith

dai

ly d

ose

fo

r 1

to 4

wee

ks

Vit

amin

KA

vian

0.2-

2.5

IMP

RN

E11

51F

or

hem

ato

chez

ia

Vit

amin

KA

vian

0.02

5-2.

5N

LB

IDF

58G

ive

ever

y 2

to 3

wee

ks

Vit

amin

KA

vian

0.2-

2.5

Par

ente

ral

NL

G24

6

Vit

amin

KL

ory

, Ch

atte

rin

g0.

2IM

BID

G42

Vit

amin

KP

sitt

acin

e0.

25-0

.5IM

q2d

-QW

E63

2N

eon

ate

do

sage

Vit

am

ins

A,

D,

EA

vian

36.3

KIU

/kg

IMQ

WE

111

Giv

e 33

KIU

vit

amin

A +

3.3

KIU

vit

amin

D p

er k

g

Vit

amin

s A

, D, E

Pig

eon

33 K

IU V

it A

/kg

IMQ

WG

590

Do

sage

bas

ed o

n V

itam

in A

Vit

amin

s A

, D, E

Psi

ttac

ine

33-6

6 K

IU/kg

IMQ

WE

1240

Fo

r def

icie

nci

es, r

epro

duct

ive

dis

ord

ers

and

bo

ne

hea

ling

Xyla

zin

e H

Cl

Am

azo

n P

arro

t1-

2IM

PR

NE

243

Add k

etam

ine

Xyl

azin

e H

Cl

Am

azo

n P

arro

t1-

2 m

g T

DIV

PR

NG

1609

Add k

etam

ine,

mix

to

geth

er in

syr

inge

, may

star

t w

ith

hal

f do

se

Xyl

azin

e H

Cl

Avi

an4

IMP

RN

E70

4A

dd k

etam

ine

Xyl

azin

e H

Cl

Avi

an2.

2IM

PR

NE

1181

Add k

etam

ine,

rev

erse

wit

h a

tip

amez

ole

,

pro

lon

ged r

eco

very

if n

ot

reve

rsed

Xyl

azin

e H

Cl

Avi

an2.

2IV

PR

NE

1431

Add k

etam

ine,

go

od f

or

sho

rt s

urg

ical

pro

cedure

s, m

ust

rev

erse

Xyl

azin

e H

Cl

Budge

riga

r6.

5IM

PR

NE

243

Add k

etam

ine

Xyl

azin

e H

Cl

Cas

sow

ary

0.25

IVP

RN

E16

17A

dd k

etam

ine,

use

yo

him

bin

e to

sh

ort

en

reco

very

Xyl

azin

e H

Cl

Cas

sow

ary

1IM

PR

NE

1617

Add k

etam

ine,

use

yo

him

bin

e to

sh

ort

en

reco

very

Xyl

azin

e H

Cl

Co

ckat

iel

2.5

IMP

RN

E24

3A

dd k

etam

ine

Xyl

azin

e H

Cl

Cra

ne

1N

LP

RN

E11

89A

dd k

etam

ine

for

anes

thes

ia

Xyl

azin

e H

Cl

Em

u0.

25IV

PR

NE

1617

Add k

etam

ine,

use

yo

him

bin

e to

sh

ort

en

reco

very

Xyl

azin

e H

Cl

Fal

con

2IM

PR

NE

243

Add k

etam

ine

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 91: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Chapter 9 | T H E R A P E U T I C A G E N T S 331

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Xyl

azin

e H

Cl

Haw

k2.

2N

LP

RN

G13

88A

dd k

etam

ine

Xyl

azin

e H

Cl

Ost

rich

0.66

IMP

RN

B44

7A

dd a

cep

rom

azin

e +

eto

rph

ine

Xyl

azin

e H

Cl

Ost

rich

150

mg

TD

IMP

RN

G28

3A

dd c

arfe

nta

nil

Xyl

azin

e H

Cl

Par

rot,

Gre

y1.

5IM

PR

NE

243

Add k

etam

ine

Xyl

azin

e H

Cl

Pig

eon

10IM

PR

NG

1481

Add b

uto

rph

ano

l + k

etam

ine

for

surg

ery

Xyl

azin

e H

Cl

Psi

ttac

ine

1-2.

2IM

-IV

PR

NE

1240

Use

in c

om

bin

atio

n w

ith

ket

amin

e 1:

3 o

r 1:

5,

reve

rse

wit

h y

oh

imb

ine

Xyl

azin

e H

Cl

Psi

ttac

ine

1-10

IMP

RN

E15

73Se

dat

ion

fo

r sm

all b

irds

at h

igh

do

sage

s

Xyl

azin

e H

Cl

Psi

ttac

ine

1-10

IMP

RN

G20

1Se

dat

ion

, sm

all p

sitt

acin

e

Xyl

azin

e H

Cl

Rap

tor

0.5

IVP

RN

D14

01A

dd k

etam

ine

Xyl

azin

e H

Cl

Rap

tor

3IM

PR

NE

4A

dd k

etam

ine

Xyl

azin

e H

Cl

Rap

tor

1-2.

2IM

-IV

PR

NE

1240

Use

in c

om

bin

atio

n w

ith

ket

amin

e 1:

3 o

r 1:

5,

reve

rse

wit

h y

oh

imb

ine

Xyl

azin

e H

Cl

Rap

tor

2IV

PR

NG

1174

Add k

etam

ine

for

diu

rnal

rap

tors

, las

ts 1

ho

ur

Xyl

azin

e H

Cl

Rap

tor

0.25

-0.5

IVP

RN

G11

74A

dd k

etam

ine,

low

er d

osa

ge r

egim

en

pro

duce

s le

ss r

esp

irat

ory

dis

turb

ance

Xyl

azin

e H

Cl

Rat

ite

2.2

IMP

RN

E4

Add k

etam

ine

Xyl

azin

e H

Cl

Rat

ite

1-2.

2IM

PR

NE

4Im

mo

bili

zati

on

Xyl

azin

e H

Cl

Rat

ite

0.5-

1IM

PR

NE

243

Add k

etam

ine

afte

r 15

min

ute

s

Xyl

azin

e H

Cl

Rat

ite

1-2.

2P

aren

tera

lP

RN

G41

8H

eavy

sed

atio

n

Xyl

azin

e H

Cl

Sto

rk0.

2-0.

4IM

PR

NE

243

Sedat

ion

Xyl

azin

e H

Cl

Swan

(B

lack

, Mute

) 2

mg

TD

IV

P

RN

G

12

91

Add k

etam

ine,

giv

e 3/

4 do

se in

itia

lly,

rem

ain

der

if n

eeded

, gas

an

esth

esia

pre

med

Xyl

azin

e H

Cl

Swan

, Mute

0.28

IVP

RN

E11

90A

dd k

etam

ine

Yeast

Cell

Deri

vati

ves

Avi

anN

/A

To

pic

alP

RN

E11

1P

rom

ote

ski

n h

ealin

g, P

rep

arat

ion

Yo

him

bin

e H

Cl

Avi

an1

IO-I

VP

RN

E24

3

Yo

him

bin

e H

Cl

Avi

an0.

1-0.

2IV

PR

NE

1181

Rev

erse

xyl

azin

e

Yo

him

bin

e H

Cl

Avi

an0.

1N

LP

RN

E12

31R

ever

sal o

f xy

lazi

ne

Yo

him

bin

e H

Cl

Avi

an0.

125-

1N

LP

RN

E14

81R

ever

se x

ylaz

ine

Yo

him

bin

e H

Cl

Budge

riga

r0.

11-0

.27

IMO

nce

G83

Yo

him

bin

e H

Cl

Cas

sow

ary

0.2

IVP

RN

E15

33Sh

ort

en k

etam

ine

+ x

ylaz

ine

anes

thes

ia

Yo

him

bin

e H

Cl

Em

u0.

2IV

PR

NE

1617

To

sh

ort

en x

ylaz

ine

reco

very

Yo

him

bin

e H

Cl

Guin

ea F

ow

l1

IVP

RN

B55

3

Yo

him

bin

e H

Cl

Guin

ea F

ow

l0.

15N

LP

RN

D14

01A

nta

gon

ize

keta

min

e/xy

lazi

ne

anes

thes

ia

**A

= P

harm

acok

inet

ic r

esea

rch;

B=

Clin

ical

eff

icac

y tr

ial;

C=

Man

ufac

ture

r’s

reco

mm

enda

tion;

D=

Pub

lishe

d w

ith r

efer

ence

; E

= P

ublis

hed

with

out

refe

renc

e; F

= E

xtra

pola

tion

from

oth

er s

peci

es;

G=

Ane

cdot

al

Page 92: CHAPTER 9 Therapeutic Agents - Avian Medicineavianmedicine.net/wp-content/uploads/2013/03/09_therapeutic_agents.pdfChapter 9| THERAPEUTIC AGENTS 243 DRUG NAME SPECIES DOSAGE (mg/kg

Cl inica l Avian Medic ine - Volume I332

DR

UG

NA

ME

SP

EC

IES

DO

SA

GE

(m

g/

kg

un

less

oth

erw

ise

state

d)

RO

UT

ED

OS

AG

E

INT

ER

VA

L

C.I

.**

RE

FE

RE

NC

EC

OM

ME

NT

S (

see r

efe

ren

ces

for

du

rati

on

, p

recau

tio

ns

an

d

co

ntr

ain

dic

ati

on

s)

Yo

him

bin

e H

Cl

Haw

k, R

ed-t

aile

d0.

1N

LP

RN

D14

01A

nta

gon

ize

keta

min

e/xy

lazi

ne

anes

thes

ia

Yo

him

bin

e H

Cl

Ost

rich

0.12

5N

LP

RN

D14

01A

nta

gon

ist

for

xyla

zin

e

Yo

him

bin

e H

Cl

Ost

rich

12.5

mg

TD

IVP

RN

G28

3

Yo

him

bin

e H

Cl

Ost

rich

0.12

5IV

PR

NG

481

Rev

erse

xyl

azin

e

Yo

him

bin

e H

Cl

Psi

ttac

ine

0.1-

0.2

IVP

RN

E12

40R

ever

se x

ylaz

ine

Yo

him

bin

e H

Cl

Rap

tor

0.1-

0.2

IVP

RN

E12

40R

ever

se x

ylaz

ine

Yo

him

bin

e H

Cl

Rap

tor

0.1

IVP

RN

G20

1

Yo

him

bin

e H

Cl

Rat

ite

0.12

5IV

PR

NG

418

Yu

nn

an

Paiy

ao

Avi

an1

ml/

kgP

OQ

DE

1435

Sto

ck s

olu

tio

n 2

cap

sule

s p

er 1

5 m

l lac

tulo

se

Yun

nan

Pai

yao

Avi

an1.

25-2

.5 m

l TD

PO

BID

G11

12M

ix w

ith

3 (

cock

atie

l) t

o 1

0 (m

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Chapter 9 | T H E R A P E U T I C A G E N T S 333

AAbbbbrreevviiaattiioonnssAbbreviation Translation

< less than

> greater than

>= greater than or equal

Bath 1 day or more in therapeutic liquid

BID two times daily

BID-q2d two times daily to every two days

BID-QID two to four times daily

BID-TID two to three times daily

cm² square centimeter

cm³ cubic centimeter

d day

d>w days to weeks

Dip less than 1 day in therapeutic liquid

doses number of doses to give

Drink drinking water

Epidural epidural injection

Feed include in feed

Flow constant flow

Flush flush

Fog fog the environment

g gram

ga gauge

GI gastrointestinal

gr grain

h hour

IA intraarticular

IA-IM intraarticular or intramuscular

ICa intracardiac

ICa-IP-IV intracardiac or intraperitoneal or intravenous

ICr intracranial

ID intradermal

IH inhalation

IM intramuscular

IM-IN-IO-IV intramuscular or intranasal or intraosseous or intravenous

IM-IN-IV intramuscular or intranasal or intravenous

IM-IO-IT-IV intramuscular or intraosseous or intratracheal or intravenous

IM-IO-IV intramuscular or intraosseous or intravenous

IM-IP intramuscular or intraperitoneal

IM-IP-IV intramuscular or intraperitoneal or intravenous

IM-IP-IV-SC intramuscular or intravenous or intraperitoneal or subcutaneous

IM-IP-PO intramuscular or intraperitoneal or by mouth

IM-IP-PO-SC intramuscular or intraperitoneal or by mouth or subcutaneous

IM-IP-SC intramuscular or intraperitoneal or subcutaneous

IM-IV intramuscular or intravenous

IM-IV-PO intramuscular or intravenous or by mouth

IM-IV-PO-SC intramuscular or intravenous or by mouth or subcutaneous

IM-IV-SC intramuscular or intravenous or subcutaneous

IM-PO intramuscular or by mouth

IM-PO-SC intramuscular or by mouth or subcutaneous

IM-SC intramuscular or subcutaneous

IM-Topical intramuscular or topical

Abbreviation Translation

IN intranasal

indef indefinite

IO intraosseous

IO-IP-IT-IV intraosseous or intraperitoneal or intratracheal or intravenous

IO-IP-IV-SC intraosseous or intraperitoneal or intravenous or subcutaneous

IO-IT-IV intraosseous or intratracheal or intravenous

IO-IV intraosseous or intravenous

IO-IV-SC intraosseous or intravenous or subcutaneous

IP intraperitoneal or intracoelomic or intrapleuroperitoneal

IP-IM intraperitoneal or intramuscular

IP-IV intraperitoneal or intravenous

IP-IV-PO intraperitoneal or intravenous or by mouth

IP-IV-SC intraperitoneal or intravenous or subcutaneous

IP-PO intraperitoneal or by mouth

IP-SC intraperitoneal or subcutaneous

IT intratracheal

IT-IV intratracheal or intravenous

IT-IV-PO intratracheal, intravenous and orally

IU International Units

IUt intrauterine

IV intravenous

IV-PO intravenous or by mouth

IV-PO-SC intravenous or by mouth or subcutaneous

IV-SC intravenous or subcutaneous

kcal kilocalories

kg kilogram

KHz kilohertz

KIU thousand International Units

L liter

life lifelong therapy

long long therapy regimen

m month

m² square meter

m³ cubic meter

MD maximum dose

mEq milliequivalent

mg milligram

min minute

MIU million International Units

ml milliliter

mm² square millimeter

mmol millimoles

mol molar solution

months for several months

N normal solution

nebulize nebulization

NL not listed

once give single dose

ophthalmic in the eye

oz ounce

Parenteral-PO parenteral or by mouth

PO by mouth

PO-SC by mouth or subcutaneous

PO-SC-Topical by mouth or subcutaneous or topical

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Cl inica l Avian Medic ine - Volume I334

Abbreviation Translation

PO-Topical by mouth or apply topically

ppm parts per million

ppt parts per thousand

PRN as needed

q10-14d every ten to fourteen days

q10d every ten days

q1-2h every one to two hours

q1-4h every one to four hours

q15min every fifteen minutes

q2-3d every two days to three days

q2-3h every two to three hours

q2-3w every two to three weeks

q2-4d every two days to four days

q2-4h every two to four hours

q2-4w every two weeks to four weeks

q2-5d every two days to five days

q2-6h every two to six hours

q2d every two days

q2d-QW every two days to every week

q2h every two hours

q2m every two months

q2w every two weeks

q30min every thirty minutes

q33h every thirty three hours

q3-4d every three to four days

q3-4h every three to four hours

q3-4w every three to four weeks

q3-5d every three to five days

q36h every thirty six hours

q3-6h every three to six hours

q3-6w every three to six weeks

q3-7d every three to seven days

q3-8h every three to eight hours

q3d every three days

q3d-q2w every 3 days to two weeks

q3d-QW every three days to every week

q3h every three hours

q3m every three months

q3w every three weeks

q4-5d every four to five days

q4-5h every four to five hours

q4-6d every four to six days

q4-6h every four to six hours

q4-6m every four to six months

q4-6w every four to six weeks

q4-8h every four to eight hours

q4d every four days

q4d-QW every four days to weekly

q4h every four hours

q4m every four months

q5d every five days

q5d-QW every five days to every week

Abbreviation Translation

q5h every five hours

q5min every five minutes

q60h every sixty hours

q6d every six days

q6m every six months

q6m-QA every six months to every year

q6w every six weeks

q7w every seven weeks

QA every year

QD every day

QD-BID every day to two times daily

QD-q2d every day or every two days

QD-q3d every day to every three days

QD-QID every day to four times daily

QD-QW every day to every week

QD-TID every day to three times daily

QH every hour

QID four times daily

QM every month

QM-q2m every month to every two months

qow every other week

QS add sufficient quantity

QW every week

QW-q10d every week to ten days

QW-q2w ever week to every two weeks

QW-q3w every week to every three weeks

r10d repeat in ten days

r2m repeat in two months

r2w repeat in two weeks

r6m repeat in six months

r7-10d repeat in seven to ten days

ra repeat annually

rm repeat in one month

rw repeat in one week

SC subcutaneous

SCJ subconjunctival

SC-Topical subcutaneous or topical

sec second

short short therapy regimen

slowly administer slowly

soln solution

TD total dose

TID three times daily

TID-q2d three times daily to every two days

TID-QID three to four times daily

topical apply topically

vapor vapor in enclosure

vent anus, rectum or cloaca

w week

weeks for several weeks

y year

µg microgram

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1691. Bowles HL: Management withpotassium bromide of seizuresof an undetermined origin inan umbrella cockatoo, ExoticDVM 5.4 7-8 2003.

1694. Levine BS: Review of antibiotic-impregnated polymethylmetha-crylate beads in avian an exoticpets, Exotic DVM 5.4 11-42003.

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1697. Harrison GJ: Amazon upperrespiratory case report, AvianExaminer 1-12 3-4 1998.

1698. Hudelson S: Use of Spartrix,Avian Examiner 1-12 4 1998.

1699. Hudelson S: Comment onprostaglandins, Avian Examiner1-12 6 1998.

1700. Cornelissen H: Treatment ofhemochromatosis, AvianExaminer 1-12 11 1998.

1702. Lightfoot T: HCG for featherpicking, Avian Examiner 1-1216 1998.

1703. Harrison GJ: Suspected poly-omavirus in finches, AvianExaminer 1-12 16 1998.

1704. McCluggage D: Nutritionaltherapy for African greys, AvianExaminer 1-12 23 1998.

1705. Harrison GJ: Home remedies,Avian Examiner 1-12 25 1998.

1707. Harrison GJ: More on heparin,Avian Examiner 1-12 27 1998.

1708. Harrison GJ: Results withHetastarch, Avian Examiner 1-12 27 1998.

1714. Flinchum G: Convulsing cock-atiels, canary, Avian Examiner1-12 35 1998.

1715. Zantop D: Cisapride use inbirds, Avian Examiner 1-12 351998.

1716. Gerlach H: Immune stimulatorsin birds, Avian Examiner 1-1236 1998.

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1721. Zantop D: Using leuprolideacetate to manage commonavian reproductive problems,Avian Examiner 18 2 1999.

1722. Hochleithner C, HochleithnerM: Treatment of liver disease inpsittacine birds, AvianExaminer 18 2-3 1999.

1723. Graham H, Vlamis G: Bachflower remedies for birds,Avian Examiner 18 4 1999.

1724. Flinchum G: Corticosteroid usein birds, Avian Examiner 20 22001.

1725. Harrison G: Uses of Avizyme,Avian Examiner 21 2 2002.

1726 Doneley B: Treatment of dia-betes mellitus in a galah, AvianExaminer 21 7 2002.

1727. What’s new, Avian Examiner 235 2003.

1728. Kramer MH: Diagnosing aviancryptosporidium, AvianExaminer 24 4 2003.

1729. Sandmeier P: Use of fipronil incanaries, Avian Examiner 25 32003.

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