CHAPTER 7 DNA: Structure and Replication CHAPTER 7 DNA: Structure and Replication Copyright 2008 ©...

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CHAPTER 7 DNA: Structure and Replication Copyright 2008 © W H Freeman and Company

Transcript of CHAPTER 7 DNA: Structure and Replication CHAPTER 7 DNA: Structure and Replication Copyright 2008 ©...

Page 1: CHAPTER 7 DNA: Structure and Replication CHAPTER 7 DNA: Structure and Replication Copyright 2008 © W H Freeman and Company.

CHAPTER 7DNA: Structure and Replication

CHAPTER 7DNA: Structure and Replication

Copyright 2008 © W H Freeman and Company

Page 2: CHAPTER 7 DNA: Structure and Replication CHAPTER 7 DNA: Structure and Replication Copyright 2008 © W H Freeman and Company.

CHAPTER OUTLINE7.1 DNA: the genetic material

7.2 The DNA structure

7.3 Semiconservative replication

7.4 Overview of DNA replication

7.5 The replisome: a remarkable replication machine

7.6 Replication in eukaryotic organisms

7.7 Telomeres and telomerase: replication termination

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Computer model of DNA

Chapter 7 Opener

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A sculpture of DNA

Figure 7-1

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DNA: the genetic material

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Transforming R cells into S cells

Figure 7-2

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DNA is the transforming agent

Figure 7-3

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The phage genetic material is DNA

Figure 7-4

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The DNA structure

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Structures of the four DNA nucleotides

Figure 7-5

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Table 7-1

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Rosalind Franklin’s critical experimental result

Figure 7-6a

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Rosalind Franklin’s critical experimental result

Figure 7-6b

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The first model of DNA

Figure 7-7

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The structure of DNA

Figure 7-8

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Two representations of the DNA double helix

Figure 7-9

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Base pairing in DNA

Figure 7-10

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Semiconservative replication

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Semiconservative DNA replication

Figure 7-11

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Three alternative models for DNA replication

Figure 7-12

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DNA is copied by semiconservative replication

Figure 7-13a

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DNA is copied by semiconservative replication

Figure 7-13b

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DNA is copied by semiconservative replication

Figure 7-13c

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A replicating bacterial chromosome

Figure 7-14

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A replicating bacterial chromosome

Figure 7-14a

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A replicating bacterial chromosome

Figure 7-14b

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Reaction catalyzed by DNA polymerase

Figure 7-15

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Overview of DNA replication

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DNA replication at the growing fork

Figure 7-16

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Synthesizing the lagging strand

Figure 7-17

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Unnumbered figure pg 281

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The replisome: a remarkable replication machine

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Proteins at work at the replication fork

Figure 7-18

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DNA gyrase removes extra twists

Figure 7-19a

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DNA gyrase removes extra twists

Figure 7-19b

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Prokaryotic initiation of replication

Figure 7-20

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Replication in eukaryotic organisms

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Assembling nucleosomes during DNA replication

Figure 7-21

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DNA replication proceeds in two directions

Figure 7-22

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DNA replication proceeds in two directions

Figure 7-22a

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DNA replication proceeds in two directions

Figure 7-22b

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Stages of the cell cycle

Figure 7-23

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Eukaryotic initiation of replication

Figure 7-24

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Telomeres and telomerase: replication termination

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The replication problem at chromosome ends

Figure 7-25

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Telomere lengthening

Figure 7-26a

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Telomere lengthening

Figure 7-26b

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The telomeric cap structure

Figure 7-27