Chapter 4 Genetic Disorders

By Mrs. Gabriel

Genetic Disorder

• Is an abnormal condition that a person inherits through genes or chromosomes.

• Caused by: mutations: forms during meiosis or already

present in a parent’s cells.

» or changes in a person's DNA.

Cystic Fibrosis

• Is a genetic disorder in which the body produces abnormally thick mucus in the lungs and intestines.

• The mucus fills the lungs making it hard to breathe.

• In the intestines it makes it difficult for digestion to take place.

• It is a recessive allele. Most common among people whose ancestors are from Northern Europe.

• No cure but drugs to prevent infection and physical therapy.

• Every day 4 babies are born with this.

Normal and Cystic Fibrosis Lung

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Sickle-Cell Disease

• Is a genetic disorder that affects the blood.

• Red blood cells become sickle –shaped.

• They cannot carry as much oxygen as normal red blood cells.

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Symptoms

• The "sickled" blood cells then are unable to squeeze through the smaller blood vessels (arterioles and capillaries). When the tissues are deprived of an adequate blood supply, painful symptoms occur. employment, and psychosocial development. 

• Complications can include stroke, bone pain, kidney damage and breathing problems. The recurrent pain caused by the disease can interfere with many aspects of the patients' lives including education,

How it is passed on.

• •

Hemophilia

•

Hemophilia is a genetic disorder in which a person’s blood clots very slowly or not at all.Caused by a recessive allele on the X chromosome.

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Down Syndrome

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Characteristics

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Karyotype and ChromosomeMapping

• •

Albinism.